CN103623288B - A kind of medicine for the treatment of chronic nephritis and preparation method thereof - Google Patents

A kind of medicine for the treatment of chronic nephritis and preparation method thereof Download PDF

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CN103623288B
CN103623288B CN201310647609.3A CN201310647609A CN103623288B CN 103623288 B CN103623288 B CN 103623288B CN 201310647609 A CN201310647609 A CN 201310647609A CN 103623288 B CN103623288 B CN 103623288B
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侯青兰
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Abstract

The invention discloses a kind of medicine for the treatment of chronic nephritis and preparation method thereof, it is mainly prepared from according to a certain weight ratio by medicines such as the Radix Astragali, Herba Leonuri, Radix Salviae Miltiorrhizae, Radix Codonopsis, Semen Cuscutae, the Rhizoma Atractylodis Macrocephalae, Rhizoma Dioscoreae, Fructus Corni, Cortex Moutans, medicine of the present invention has heat-clearing and toxic substances removing, eliminating dampness and diuresis, the function of strengthening the spleen stomach function regulating, be used for the treatment of chronic nephritis instant effect, short treating period, cure rate is high.

Description

A kind of medicine for the treatment of chronic nephritis and preparation method thereof
Technical field
The present invention relates to a kind of medicine for the treatment of chronic nephritis and preparation method thereof, belong to the field of Chinese medicines.
Technical background
Chronic glomerulonephritis is referred to as chronic nephritis, and mean that albuminuria, hematuria, edema are basic clinical, mode of onset is had nothing in common with each other, protracted inflammation; pathological changes is slowly in progress, can renal hypofunction in various degree, develops into one group of glomerulopathy of chronic renal failure the most at last.Due to histological type and the stadium difference of this group disease, main clinical manifestation is different, and disease indicia is in variation.At present, western medicine chronic nephritis poor effect, and long-term taking Western medicine has more side effect, therefore, there is very large demand to the Chinese medicine of effectively treating chronic nephritis in people.
Summary of the invention
The present inventor, according to the research of theory of Chinese medical science and clinical test repeatedly and checking, finally have found the medicine of effectively treatment chronic nephritis, thus completes the present invention.
Object of the present invention is just to provide a kind of composition of medicine effectively can treating chronic nephritis.
Another object of the present invention just there is provided the preparation method of this composition of medicine.
Medicine of the present invention selects the Radix Astragali, Herba Leonuri, Radix Salviae Miltiorrhizae, Radix Codonopsis, Semen Cuscutae, the Rhizoma Atractylodis Macrocephalae, Rhizoma Dioscoreae, Fructus Corni, Cortex Moutan, the Cortex Eucommiae, Radix Aconiti Lateralis Preparata, the Rhizoma Anemarrhenae, Semen Coicis, Herba Taxilli, Radix Achyranthis Bidentatae, Semen Plantaginis, Semen Nelumbinis, Fructus Jujubae medicine to combine, made by these drug regimens each efficacy of drugs produce synergism, thus effectively can treat the recurrence of chronic nephritis.Wherein select the Radix Astragali to be that tepor, enters lung, spleen channel because its nature and flavor are sweet, life defends consolidating superficial resistance with useful, inducing diuresis to remove edema, poison holding, and the function of granulation promoting, controls spontaneous perspiration, night sweat, arthralgia due to stagnation of blood, edema, and carbuncle is not burst or burst and holds back for a long time; Processing the function with there being invigorating middle warmer benefit, controlling internal injury overstrain, diarrhea due to hypofunction of the spleen, proctoptosis, deficiency of vital energy blood prostration, the disease of metrorrhagia and leukorrhagia and all weakness of QI blood deficiency.Select Herba Leonuri to be that cool, enter pericardium, Liver Channel, invigorate blood circulation, blood stasis dispelling, regulating menstruation, the function of the water that disappears, controls menoxenia because its nature and flavor are worked hard, control and Lou have difficult labour, retention of placenta, puerperal blood faints, abdominal pain due to blood stasis, metrorrhagia and metrostaxis, hematuria, rushes down blood, carbuncle skin infection.Radix Salviae Miltiorrhizae is selected to be that tepor, enters the heart, Liver Channel, have activating blood circulation and dissipating phlegm, calming heart and tranquilizing mind, evacuation of pus, and the function of pain relieving, controls angina pectoris, menoxenia, dysmenorrhea, amenorrhea, and metrorrhagia leukorrhagia , mass in the abdomen, gathers, abdominal pain due to blood stasis, arthralgia because its nature and flavor are bitter, palpitation with fear sleeplessness, malignant boil toxic swelling.Select Radix Codonopsis to be because its nature and flavor are sweet, flat, start with, meridian of Foot-TAI YIN edema caused by disorder of QI, have invigorating the spleen and replenishing QI, the function of promoting the production of body fluid, controls weakness of the spleen and stomach, deficiency of both QI and blood, fatigue and lack of strength, and lack of appetite is thirsty, chronic diarrhea, proctoptosis.Select Semen Cuscutae to be because its property acrid-sweet flavor, flat, enter liver, kidney channel, have invigorating the liver and kidney, beneficial marrow, the function of improving eyesight, controls soreness of waist and knee joint, and seminal emission, quench one's thirst, dripping urination, order is dark.Select the Rhizoma Atractylodis Macrocephalae to be because its property bitter but sweet flavor, temperature, enters spleen, stomach warp, has spleen reinforcing, stomach reinforcing, dampness, and in function, control deficient QI of the spleen and stomach, anorexia, asthenia weak breath, deficiency-distension, has loose bowels, phlegm retention, edema, jaundice, arthralgia chiefly caused by damp pathogen, dysuria, dizzy, spontaneous perspiration, and nausea is uneasy.Select Rhizoma Dioscoreae to be because its nature and flavor are sweet, flat, enter lung, spleen, kidney channel, have spleen invigorating, tonifying the lung, reinforce the kidney, the function of benefit essence, controls diarrhea due to hypofunction of the spleen, chronic dysentery, cough due to consumptive disease, quenches one's thirst, seminal emission, leukorrhagia, frequent micturition.Fructus Corni is selected to be that tepor, enters liver, kidney channel, have invigorating the liver and kidney, arresting seminal emission gas, Gu the function of collapse, controls soreness of waist and knee joint, dizzy, tinnitus, sexual impotence, and seminal emission, frequent micturition, deficiency of the liver cold and heat, incessant sweating due to debility, the heart shakes scattered pulse because its nature and flavor acid.Cortex Moutan is selected to be because its nature and flavor are worked hard, cool, enter the heart, liver, kidney channel, have heat clearing away, removing heat from blood, and blood, the function of repercussive, controls the pathogenic heat attacking blood system in febrile diseases, and send out speckle , Jing Epilepsy, tell, be defeated in battle, have blood in stool, hectic fever due to YIN-deficiency consumptive fever, amenorrhea , mass in the abdomen, carbuncle and ulcer, flutters damage.Select the Cortex Eucommiae be because its nature and flavor sweet micro-pungent, temperature, enter liver, kidney channel, have invigorating the liver and kidney, bone and muscle strengthening, antiabortive function, control spinal column ache, foot and knee flaccidity, dribbling urination, uncontrolled urination is itched, vaginal bleeding during pregnancy for falling, hypertension.Radix Aconiti Lateralis Preparata is selected to be because its property acrid-sweet flavor, heat, poisonous, enter the heart, spleen, kidney channel, have recuperating depleted YANG to mend fire, the function of dispelling cold and removing dampness, control excessive YIN keeping YANG externally, loss of YANG due to profuse perspiration, vomiting and diarrhea is fainted inverse, trusted subordinate's cold type of pain, the splenic diarrhea cold-dysentery, beriberi edema, children's's intermittent infantile convulsion, the contracture of anemofrigid-damp arthralgia , Wei lame, the disease of the leakage of carbuncle of yin nature skin ulcer and all chronic diseaseses.The Rhizoma Anemarrhenae is selected to be because its nature and flavor are bitter, cold, enter lung, stomach, kidney channel, have nourishing YIN to lower pathogenic fire, moisturize the function of laxation, control dysphoria with smothery sensation and quench one's thirst, hectic fever due to YIN-deficiency consumptive fever, cough due to lung-heat, constipation due to dry stool, dysuria.Semen Coicis is selected to be that cool, enter spleen, lung, kidney channel, have spleen invigorating, tonifying the lung, heat clearing away, the function of dampness removing, controls and have loose bowels, arthralgia chiefly caused by damp pathogen, the contracture of muscle arteries and veins, joint stuffiness, edema, beriberi, consumptive lung disease, lung abscess, acute appendicitis, stranguria with turbid discharge, leucorrhea because its property slightly sweet flavor.Select Herba Taxilli to be because its property bitter but sweet flavor, flat, enter liver, kidney channel, have invigorating the liver and kidney, bone and muscle strengthening, except rheumatism, the meridian dredging, beneficial blood, antiabortive function, controls soreness of waist and knee joint, and muscles and bones flaccidity is weak, hemiplegia, beriberi, anemofrigid-damp arthralgia, vaginal bleeding during pregnancy metrorrhagia, lack of lactation after delivery.Select Radix Achyranthis Bidentatae to be because its nature and flavor sweetness and bitterness acid, flat, enter liver, kidney channel, life uses dissipating blood stasis blood, subduing inflammation, controls gonorrhea, hematuria, amenorrhea , mass in the abdomen, difficult labour, retention of placenta, postnatal blood stasis is suffered from abdominal pain, sore throat, carbuncle, traumatic injury, ripe invigorating the liver and kidney, bone and muscle strengthening, controls waist kneecap pain, four fertile contractures, flaccidity syndrome and arthralgia syndrome.Semen Plantaginis is selected to be that cold, enter kidney, urinary bladder channel, have diuretic, heat clearing away, improving eyesight, the function of eliminating the phlegm, controls urinary obstruction, stranguria with turbid discharge, leukorrhagia, hematuria, heat-damp in summer dysentery, cough ant phlegm, and arthralgia chiefly caused by damp pathogen, conjunctival congestion is hidden from view because its nature and flavor are sweet.Semen Nelumbinis are selected to be because its property sweet-puckery flavor, flat, enter the heart, spleen, kidney channel, nourish heart, kidney tonifying, spleen reinforcing, the function of astringing intestine to stop diarrhea, control dreaminess of sleeping night, seminal emission, stranguria with turbid discharge, chronic dysentery, diarrhea of deficiency type, married woman's bleeding not during menses.Select Fructus Jujubae to be that temperature, enters spleen, stomach warp, have spleen reinforcing stomach function regulating, supplementing QI for promoting the production of body fluid because its nature and flavor are sweet, adjust battalion to defend, separate the function of poison of drug, control insufficiency of stomach lack of appetite, the weak loose stool of spleen, qi-blood-body fluid is not enough, disharmony of nutrient QI with defensive QI, severe palpitation, woman hysteria.
Detailed description of the invention
The drug dose of instant component is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good therapeutic effect within the scope of following weight
Radix Astragali 15-25 gram of Herba Leonuri 15-25 gram of Radix Salviae Miltiorrhizae 10-20 gram
Radix Codonopsis 5-15 gram of Semen Cuscutae 5-15 gram of Rhizoma Atractylodis Macrocephalae 5-15 gram
Rhizoma Dioscoreae 15-25 Keshan Fructus Evodiae 10-20 gram of Cortex Moutan 5-15 gram
Cortex Eucommiae 5-15 gram of Radix Aconiti Lateralis Preparata 5-15 gram of Rhizoma Anemarrhenae 5-15 gram
Semen Coicis 15-25 gram of Herba Taxilli 5-15 gram of Radix Achyranthis Bidentatae 5-15 gram
Semen Plantaginis 5-15 gram of Semen Nelumbinis 10-20 gram of Fructus Jujubae 5-15 gram
Preferable amount is
The Radix Astragali 20 grams of Herba Leonuris 20 grams of Radix Salviae Miltiorrhizaes 15 grams
Radix Codonopsis 10 grams of Semen Cuscutae 10 grams of Rhizoma Atractylodis Macrocephalaes 10 grams
The Rhizoma Dioscoreae 20 Keshan Fructus Evodiae 15 grams of Cortex Moutans 10 grams
The Cortex Eucommiae 10 grams of Radix Aconiti Lateralis Preparatas 10 grams of Rhizoma Anemarrhenaes 10 grams
Semen Coicis 20 grams of Herba Taxillis 10 grams of Radix Achyranthis Bidentataes 10 grams
10 grams, Semen Plantaginis 10 grams of Semen Nelumbinis 15 grams of Fructus Jujubaes
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, the Radix Astragali: pick clean impurity, the root head that removing is residual and hollow larger root, be soaked in water, pull out, and section, dries;
2, Herba Leonuri: pick decontamination, cleans, runs through, cutting, dry;
3, Radix Salviae Miltiorrhizae: pick clean impurity, removing rhizome, cleans, pulls out, run through rear section, dry;
4, Radix Codonopsis: run through after cleaning silt impurity, section or cutting, dry;
5, Semen Cuscutae: sieve and remove impurity, cleans, dries;
6, the Rhizoma Atractylodis Macrocephalae: pick clean impurity, be soaked in water, pull out after bubble, run through, section, dries;
7, Rhizoma Dioscoreae: pick clean impurity, is soaked in water when softening to Rhizoma Dioscoreae central part, pulls out and slightly dry in the air, and section is dried or dried;
8, Fructus Corni: clean, except removal core and impurity, dry;
9, Cortex Moutan: pick decontamination, cleans, runs through, and section, dries;
10, the Cortex Eucommiae: removing rough bark, clean, run through, dice or strand, dry;
11, Radix Aconiti Lateralis Preparata: be soaked in water, pulls out, and section, dries;
12, the Rhizoma Anemarrhenae: pick clean impurity, hit with water and wash, pull out, soften, section is dried;
13, Semen Coicis: get crude drug, removing residual cot, impurity;
14, Herba Taxilli: wash, runs through, and cutting is dried;
15, Radix Achyranthis Bidentatae: pick decontamination, cleans, softens, cutting, dry;
16, Semen Plantaginis: pick decontamination, sieve removes spare, empty grain;
17, Semen Nelumbinis: pick most impurity, or smash, remove the peel, go the heart to use;
18, Fructus Jujubae: pick clean impurity, dry.
Two, prepare
1, the Radix Astragali of described weight, Herba Leonuri, Radix Salviae Miltiorrhizae, Radix Codonopsis, Semen Cuscutae, the Rhizoma Atractylodis Macrocephalae, Rhizoma Dioscoreae, Fructus Corni, Cortex Moutan, the Cortex Eucommiae, Radix Aconiti Lateralis Preparata, the Rhizoma Anemarrhenae, Semen Coicis, Herba Taxilli, Radix Achyranthis Bidentatae, Semen Plantaginis, Semen Nelumbinis, Fructus Jujubae medicine are decocted with water secondary, add water 6 times amount for the first time, soak after 150 minutes, intense fire decocts boiling 30 minutes, use slow fire boiling again 30 minutes, filter first time decoction liquor.
2, add water the medicinal residues of filtration 4 times amount, first boils with very hot oven, then use slow fire boiling 20 minutes, filters to obtain second time decoction liquor.
3, by twice decoction liquor mixing and stirring, be divided into 3 doses and take.
Medicine of the present invention has heat-clearing and toxic substances removing, eliminating dampness and diuresis, and the function of strengthening the spleen stomach function regulating, is used for the treatment of chronic nephritis, short treating period, instant effect, non-relapse after healing, has no side effect.
Detailed description of the invention
Set forth the beneficial effect of medicine of the present invention further below by way of test example, these test examples comprise animal toxicity test report and the clinical observation on the therapeutic effect data of medicine of the present invention.
The animal toxicity test report of [test example 1] medicine of the present invention
Get rabbit 30, male and female dual-purpose, body weight 2.0-2.4kg, divide two groups, often organize 15, wherein one group is overdose test group, and another group is normal amount test group.Super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is administration by gavage administration, every day 2 times, serve on 7 days, observes administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.
The clinical observation material of [test example 2] Drug therapy chronic nephritis of the present invention
1, physical data
Accept out-patient's totally 155 examples for medical treatment.
2, diagnostic criteria
Different according to clinical manifestation, be divided into following five hypotypes:
(1) plain edition
Comparatively common.The course of disease is delayed, and the state of an illness is relatively stable, shows as the slight edema to moderate, hypertension and renal function injury more.Urine protein (+) ~ (+++), microscopic hematuria and cylinderuria etc.Pathological change is with IgA nephropathy, and non-IgA mesangial proliferative nephritis, focal mesangial matrix * is more common, also shows in FSGS and (in early days) membranoproliferative nephritis etc.
(2) nephrotic High-grade Proteinuria
Except having medium-sized performance, some patients can show nephrotic High-grade Proteinuria, and pathological is common with minimal change nephropathy, membranous nephropathy, membranoproliferative nephritis, focal glomerular sclerosis etc.
(3) hypertension
Except the performance of above-mentioned plain edition, increase as main manifestations with the medium degree blood pressure of persistence, particularly diastolic pressure continues to increase, and often with eye ground tremulous pulse carefully narrow, tortuous and artery and vein crossing sign, minority can have cotton-shaped exudate and (or) hemorrhage.Pathology is common with Focal segmental glomerulosclerosis and diffusivity hypertrophy or late period can not shape or have more glomerular sclerosis to show.
(4) mixed type
The performance of existing Glomerulonephritis Nephropathy has again hypertension show clinically, with renal hypofunction sign in various degree simultaneously.Pathological change can be Focal segmental glomerulosclerosis and late period diffuse hyperplastic glomerulonephritis etc.
(5) acute attack type
In the state of an illness in relatively stable or continuing advances process, due to factors such as the infection such as antibacterial or virus or overwork, through shorter incubation period (1 ~ 5 day), and there is the clinical manifestation of similar acute nephritis, original maintenance level can be returned to or sb.'s illness took a turn for the worse through treatment with after having a rest, gradually uremia occur; Or recurrent exerbation repeatedly after, renal function sharply goes down and occurs uremia's series of clinical manifestations.Pathological change is diffusivity hypertrophy, glomerular sclerosis basis occurs crescent and (or) obvious interstitial nephritis.
3, Therapeutic Method
Select above-mentioned medicament, take to patient, each serving with 1 dose, every day 2 times 15 days is a course for the treatment of, takes 4 courses for the treatment of continuously.
4, efficacy assessment standard
Effective: chronic nephritis transference cure, body constitution recovers normal, observes half a year without recidivist;
Take a turn for the better: chronic nephritis symptom is clearly better, and body constitution is progressively recovered;
Invalid: not reach improvement standard person.
5, therapeutic outcome (seeing the following form)
In above-mentioned treatment, by Drug therapy patients with chronic glomerulonephritis 155 example of the present invention, effective 149 examples of result, obvious effective rate is 96.13%, and take a turn for the better 4 examples, and improvement rate is 2.58%, and invalid 2 examples, total effective rate is 98.71%.

Claims (3)

1. treat a medicine for chronic nephritis, it is characterized in that: it is made up of the crude drug in following weight range:
Radix Astragali 15-25 gram of Herba Leonuri 15-25 gram of Radix Salviae Miltiorrhizae 10-20 gram
Radix Codonopsis 5-15 gram of Semen Cuscutae 5-15 gram of Rhizoma Atractylodis Macrocephalae 5-15 gram
Rhizoma Dioscoreae 15-25 Keshan Fructus Evodiae 10-20 gram of Cortex Moutan 5-15 gram
Cortex Eucommiae 5-15 gram of Radix Aconiti Lateralis Preparata 5-15 gram of Rhizoma Anemarrhenae 5-15 gram
Semen Coicis 15-25 gram of Herba Taxilli 5-15 gram of Radix Achyranthis Bidentatae 5-15 gram
Semen Plantaginis 5-15 gram of Semen Nelumbinis 10-20 gram of Fructus Jujubae 5-15 gram.
2. medicine according to claim 1, wherein the consumption of each crude drug is:
The Radix Astragali 20 grams of Herba Leonuris 20 grams of Radix Salviae Miltiorrhizaes 15 grams
Radix Codonopsis 10 grams of Semen Cuscutae 10 grams of Rhizoma Atractylodis Macrocephalaes 10 grams
The Rhizoma Dioscoreae 20 Keshan Fructus Evodiae 15 grams of Cortex Moutans 10 grams
The Cortex Eucommiae 10 grams of Radix Aconiti Lateralis Preparatas 10 grams of Rhizoma Anemarrhenaes 10 grams
Semen Coicis 20 grams of Herba Taxillis 10 grams of Radix Achyranthis Bidentataes 10 grams
10 grams, Semen Plantaginis 10 grams of Semen Nelumbinis 15 grams of Fructus Jujubaes.
3. the preparation method of medicine according to claim 1 or 2, is characterized in that: it comprises the following steps:
(1) get the raw materials ready
(1) Radix Astragali: pick clean impurity, the root head that removing is residual and hollow larger root, be soaked in water, pull out, and section, dries;
(2) Herba Leonuri: pick decontamination, cleans, runs through, cutting, dry;
(3) Radix Salviae Miltiorrhizae: pick clean impurity, removing rhizome, cleans, pulls out, run through rear section, dry;
(4) Radix Codonopsis: run through after cleaning silt impurity, section or cutting, dry;
(5) Semen Cuscutae: sieve and remove impurity, cleans, dries;
(6) Rhizoma Atractylodis Macrocephalae: pick clean impurity, be soaked in water, pull out after bubble, run through, section, dries;
(7) Rhizoma Dioscoreae: pick clean impurity, is soaked in water when softening to Rhizoma Dioscoreae central part, pulls out and slightly dry in the air, and section is dried or dried;
(8) Fructus Corni: clean, except removal core and impurity, dry;
(9) Cortex Moutan: pick decontamination, cleans, runs through, and section, dries;
(10) Cortex Eucommiae: removing rough bark, clean, run through, dice or strand, dry;
(11) Radix Aconiti Lateralis Preparata: be soaked in water, pulls out, and section, dries;
(12) Rhizoma Anemarrhenae: pick clean impurity, hit with water and wash, pull out, soften, section is dried;
(13) Semen Coicis: get crude drug, removing residual cot, impurity;
(14) Herba Taxilli: wash, runs through, and cutting is dried;
(15) Radix Achyranthis Bidentatae: pick decontamination, cleans, softens, cutting, dry;
(16) Semen Plantaginis: pick decontamination, sieve removes spare, empty grain;
(17) Semen Nelumbinis: pick most impurity, or smash, remove the peel, go the heart to use;
(18) Fructus Jujubae: pick clean impurity, dry;
(2) prepare
(1) Radix Astragali of described weight, Herba Leonuri, Radix Salviae Miltiorrhizae, Radix Codonopsis, Semen Cuscutae, the Rhizoma Atractylodis Macrocephalae, Rhizoma Dioscoreae, Fructus Corni, Cortex Moutan, the Cortex Eucommiae, Radix Aconiti Lateralis Preparata, the Rhizoma Anemarrhenae, Semen Coicis, Herba Taxilli, Radix Achyranthis Bidentatae, Semen Plantaginis, Semen Nelumbinis, Fructus Jujubae medicine are decocted with water secondary, add water 6 times amount for the first time, soak after 150 minutes, intense fire decocts boiling 30 minutes, use slow fire boiling again 30 minutes, filter first time decoction liquor;
(2) add water the medicinal residues of filtration 4 times amount, first boils with very hot oven, then use slow fire boiling 20 minutes, filters to obtain second time decoction liquor;
(3) by twice decoction liquor mixing and stirring, be divided into 3 doses and take.
CN201310647609.3A 2013-12-06 2013-12-06 A kind of medicine for the treatment of chronic nephritis and preparation method thereof Expired - Fee Related CN103623288B (en)

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CN104873834A (en) * 2015-05-26 2015-09-02 慕常松 Traditional Chinese medicine composition for treating chronic nephritis
CN105148107A (en) * 2015-08-21 2015-12-16 王莉 Medicine for treating nephrosis and preparation method of medicine
CN105126089A (en) * 2015-10-13 2015-12-09 贾金玲 Chinese and western medicine combined preparation for treating nephritis and preparing method thereof
CN105126090A (en) * 2015-10-13 2015-12-09 贾金玲 Multi-enzyme Chinese and western medicine composite preparation for treating chronic nephritis and preparing method
CN106237172A (en) * 2016-08-30 2016-12-21 山东中医药大学 A kind of compound medicine treating kidney region fibrosis
CN116850221B (en) * 2023-07-20 2024-06-11 山东省科学院菏泽分院 A peony stamen dodder complex and its preparation method and application

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CN1626185A (en) * 2003-12-08 2005-06-15 刘立全 Capsule for treating kidney disease
CN101095794A (en) * 2007-07-05 2008-01-02 北京艺信堂医药研究所 Chinese traditional medicine preparations for treating drug-induced nephritis
CN101284059A (en) * 2007-04-11 2008-10-15 西安芳草园医药科技有限公司 Chinese medicinal materials preparation for reinforcing the spleen and kidney and curing the chronic nephritis

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1626185A (en) * 2003-12-08 2005-06-15 刘立全 Capsule for treating kidney disease
CN101284059A (en) * 2007-04-11 2008-10-15 西安芳草园医药科技有限公司 Chinese medicinal materials preparation for reinforcing the spleen and kidney and curing the chronic nephritis
CN101095794A (en) * 2007-07-05 2008-01-02 北京艺信堂医药研究所 Chinese traditional medicine preparations for treating drug-induced nephritis

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