CN103735889B - A kind of medicine for the treatment of pyelonephritis and preparation method thereof - Google Patents

A kind of medicine for the treatment of pyelonephritis and preparation method thereof Download PDF

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CN103735889B
CN103735889B CN201310678564.6A CN201310678564A CN103735889B CN 103735889 B CN103735889 B CN 103735889B CN 201310678564 A CN201310678564 A CN 201310678564A CN 103735889 B CN103735889 B CN 103735889B
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郑明立
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Abstract

The invention discloses a kind of medicine for the treatment of pyelonephritis and preparation method thereof, it is mainly prepared from according to a certain weight ratio by medicines such as Rhizoma Imperatae, Herba Cirsii, Cortex Lycii, Radix Serissae, Folium Pyrrosiae, Herba Duchesneae Indicae, Fructus Foeniculi, Lumbricus, Radix Paeoniae Rubra, medicine of the present invention has heat-clearing and toxic substances removing, relieving stranguria by diuresis, the function that lung heat clearing expels the heat-evil, be used for the treatment of pyelonephritis instant effect, good effect, have no side effect.

Description

A kind of medicine for the treatment of pyelonephritis and preparation method thereof
Technical field
The present invention relates to a kind of medicine being used for the treatment of pyelonephritis and preparation method thereof, belong to the field of Chinese medicines.
Technical background
Pyelonephritis refers to renal pelvis inflammation, is mostly caused by bacteriological infection, and pyelonephritis is also known as upper urinary tract infection, and general companion's lower urinary tract inflammation, not easily strictly distinguishes clinically.According to clinical disease course and disease, pyelonephritis can be divided into acute and chronic two phases, and chronic pyelonephritis is the major reason causing chronic renal insufficiency.The multiple women being born in the childbearing age of acute pyelonephritis, patient often has lumbago, kidney district tenderness, kowtows pain, accompanies shiver with cold, generates heat, the General Symptomies such as headache, nausea and vomiting, and the bladder irritation such as urine urgency-frequency and dysurea is levied, and the visible leukocyte of blood count increases.General without hypertension or azotemia.Patient urine is muddy, and can have gross hematuria, routine urinalysis microscopy has volume leukocyte or pus cell, can have a little erythrocyte and cast, and albumen is a little to moderate.At present, western medicine pyelonephritis poor effect, and long-term taking Western medicine has more side effect, therefore, there is very large demand to the Chinese medicine of effectively treating pyelonephritis in people.
Summary of the invention
The present inventor, according to the research of theory of Chinese medical science and clinical test repeatedly and checking, finally have found the medicine of effectively treatment pyelonephritis, thus completes the present invention.
Object of the present invention is just to provide a kind of composition of medicine effectively can treating pyelonephritis.
Another object of the present invention just there is provided the preparation method of this composition of medicine.
Medicine of the present invention selects Rhizoma Imperatae, Herba Cirsii, Cortex Lycii, Radix Serissae, Folium Pyrrosiae, Herba Duchesneae Indicae, Fructus Foeniculi, Lumbricus, Radix Paeoniae Rubra, Folium Bambusae, Folium Nelumbinis, Radix Phytolaccae, Radix Arnebiae (Radix Lithospermi), Semen Phaseoli, Talcum, Caulis Lonicerae, Semen Armeniacae Amarum, Bombyx Batryticatus, Radix Carpesii, Herba Violae, Rhizoma Phragmitis, Stigma Maydis, Herba Pogostemonis, Ganoderma, Endothelium Corneum Gigeriae Galli, Rhizoma Cibotii, Rhizoma Paridis, Spora Lygodii, Fructus Psoraleae, Polyporus, Cortex Moutan, Gypsum Fibrosum medicine to combine, each efficacy of drugs is made by these drug regimens to produce synergism, thus can the recurrence of fast treating pyelonephritis.Wherein select Rhizoma Imperatae to be sweet because of its nature and flavor, cold, enter lung, stomach, small intestine meridian, have removing heat from blood, hemostasis, heat clearing away, the function of diuresis, controls calentura excessive thirst, spits blood, epistaxis, lung-heat dyspnea with rapid respiration, gastric heat hiccup, gonorrhea, dysuria, edema, jaundice.Select Herba Cirsii to be because its nature and flavor are pungent, temperature, enter spleen, stomach two warp, have warming middle-JIAO, the therapeutic method to keep the adverse QI flowing downwards, rapid digestion of food, the function of parasite killing, controls vomiting and diarrhoea, trusted subordinate's distending pain, furuncle toxic swelling skin ulcer, and poisonous insect flood dragon hinders.Optionally Cortex Lycii is because its nature and flavor are sweet, cold, and enter lung, liver, kidney channel, have heat clearing away, the function of removing heat from blood, control asthenia hectic fever night sweat, lung-heat cough with asthma, spit blood, epistaxis, stranguria with blood, quenches one's thirst, hypertension, carbuncle, malignant boil.Radix Serissae is selected to be because its nature and flavor toil, cool, dispel the wind, dampness removing, heat clearing away, the function of removing toxic substances, dispelling the wind and dampness pathogens lumbago and skelalgia, dysentery, edema, conjunctival congestion and swelling pain, laryngalgia, toothache, women leucorrhea, carbuncle subcutaneous ulcer, scrofula.Select Folium Pyrrosiae to be because its property bitter but sweet flavor, cool, enter lung, urinary bladder channel, have relieving stranguria by diuresis, the function that lung heat clearing expels the heat-evil, control and drench pain, hematuria, lithangiuria, kidney is, metrorrhagia, dysentery, cough due to lung-heat, chronic tracheitis, incised wound, carbuncle.Select Herba Duchesneae Indicae to be because its nature and flavor sweetness and bitterness, cold, poisonous, have heat clearing away, removing heat from blood, detumescence, the function of removing toxic substances, controls calentura , Jing Epilepsy, and cough is spitted blood, laryngopharynx swelling and pain, dysentery, carbuncle, furuncle, snake bite and insect sting, burn.Select Fructus Foeniculi to be that temperature, returns liver,kidney,spleen, stomach warp, have dispersing cold for relieving pain, the function of regulating qi-flowing for harmonizing stomach because its nature and flavor are pungent, control colic of cold type stomachache, the testis swelling and hanging down of either of the testes, dysmenorrhea, few abdomen cold type of pain, distension and fullness in the abdomen, lack of appetite and vomiting, hydrocele of testis.Lumbricus is selected to be because its nature and flavor are salty, cold, enter liver, spleen, lung meridian, have heat clearing away, suppressing the hyperactive liver, Zhichuan, the function of dredging collateral, control high fanatical hot-tempered, convulsion with spasms, headache due to pathogenic wind-heat, conjunctival congestion, apoplexy and hemiplegia, pants, sore throat, arthralgia, bleeding from the gum, urinary obstruction, scrofula, mumps, skin infection.Select Radix Paeoniae Rubra to be because its nature and flavor are bitter, be slightly cold, return Liver Channel, have clearing away heat and cooling blood, the function of eliminating stasis to stop pain, control warm poison and go mad, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea , Epilepsy abdominal mass is suffered from abdominal pain, injury from falling down, carbuncle skin infection.Select Folium Bambusae to be because its property slightly sweet flavor, cold, enter the heart, lung, gallbladder, stomach warp, have clearing heat and relieving fidgetness, the function of diuresis of promoting the production of body fluid, control that calentura is tired drinks, little youngster shies Epilepsy, and cough with dyspnea tells nosebleed, flushed complexion, oliguria with reddish urine, erosion of the oral mucosa tongue boil.Select Folium Nelumbinis to be because its nature and flavor are pained, flat, enter the heart, liver, spleen channel, have clearing away summer-heat and eliminating dampness, sending up the lucid YANG, the function of hemostasis, control diarrhea due to summer heat and dampness, dizzy, aqueous vapor edema, thunder-headache, spit blood, epistaxis, metrorrhagia, has blood in stool, puerperal blood faints.Radix Phytolaccae is selected to be because its nature and flavor are bitter, cold, poisonous, enter spleen, urinary bladder channel, have logical two just, removing water retention by purgation, the function of eliminating stagnation, harness the river swollen, distension, beriberi, sore throat, carbuncle, malignant boil.Radix Arnebiae (Radix Lithospermi) is selected to be because its nature and flavor earnestly, are trembled with fear, entered percardium, Liver Channel, have removing heat from blood, invigorate blood circulation, the function of heat-clearing and toxic substances removing, control warm macule, jaundice due to damp-heat, purpura, tell, be defeated in battle, hematuria, stranguria with turbid discharge, dysentery, constipation with heat retention, burn, eczema, erysipelas, carbuncle and ulcer.Semen Phaseoli is selected to be because the sweet acid of its nature and flavor, flat, enter the heart, small intestine meridian, have diuretic to dehumidify, and blood evacuation of pus, the function of subduing swelling and detoxicating, harnesses the river swollen, beriberi, jaundice, and dysentery, has blood in stool, carbuncle.Talcum is selected to be because its nature and flavor are sweet, light, cold, return bladder, lung, stomach warp, have inducing diuresis for treating stranguria syndrome, heat-clearing and toxic substances removing, the function of damp eliminating expelling summer-heat, control hematodiarrhoea, gonorrhea, urinate hot puckery pain, heat-damp in summer excessive thirst, damp and hot watery diarrhea, external treatment eczema, eczema, miliaria.Caulis Lonicerae is selected to be because its nature and flavor are sweet, cold, enter the heart, lung meridian, have heat clearing away, removing toxic substances, the function of dredging collateral, control epidemic febrile disease heating, toxic-heat and blood stasis, infectious hepatitis, carbuncle sore tumefacting virus, bones and muscles pain.Semen Armeniacae Amarum is selected to be that temperature, poisonous, enter lung, large intestine channel, have expelling phlegm for arresting cough, relieving asthma, the function of intestine moistening, controls exogenous cough, dyspnea with fullness of the chest, sore throat, dryness of the intestine constipation because its nature and flavor are bitter.Bombyx Batryticatus is selected to be because its nature and flavor are pungent salty, flat, enter liver, lung, stomach warp, have expelling wind to relieve convulsion, the function of dissipating phlegm and resolving masses, control apoplectic aphasia , Jing Epilepsy, wind syndrome of head, acute throat trouble, sore throat, scrofula tuberculosis, wind skin ulcer urticaria, erysipelas, mastitis.Select Radix Carpesii to be because its nature and flavor are pungent, cold, enter liver, lung meridian, eliminate the phlegm, heat clearing away, removing blood stasis, hemostasis, removing toxic substances, the function of parasite killing, controls tonsillitis, sore throat, malaria, acute hepatitis, anxious chronic infantile convulsion, malnutrition due to parasitic infestation, abdominal mass due to blood stasis, epistaxis, stranguria with blood, and furuncle swells sore, itchy skin eruption.Select Herba Violae to be that GUIXIN, Liver Channel, have heat-clearing and toxic substances removing because its nature and flavor bitter, acrid, cold, the function of removing heat from blood detumescence, controls furuncle swelling toxin, carbuncle carbuncle on the back, erysipelas, venom.Rhizoma Phragmitis is selected to be that cold, enter lung, stomach warp, has heat clearing away, promotes the production of body fluid, relieving restlessness, and the function of preventing or arresting vomiting controls calentura excessive thirst, gastropyretic vomiting, dysphagic, regurgitation, consumptive lung disease, lung abscess, and separates Fugu ocellatus ichthyotoxin because its nature and flavor are sweet.Stigma Maydis is selected to be that flat, have diuresis, expel the heat-evil, suppressing the hyperactive liver, the function of function of gallbladder promoting, controls oedema due to nephritis, beriberi, icterohepatitis, hypertension, cholecystitis, cholelithiasis, diabetes, hematemesis and epistaxis, nasal sinusitis, acute mastitis because its nature and flavor are sweet.Herba Pogostemonis is selected to be that tepor, enters lung, spleen, stomach warp, have fast gas because its nature and flavor are pungent, and in, ward off dirty, the function of damp eliminating, cure cold heat-damp in summer, cold and heat, and headache, breast gastral cavity painful abdominal mass is vexed, and vomiting is had loose bowels, malaria, dysentery, halitosis.Ganoderma is selected to be that flat, GUIXIN, lung, liver, kidney channel, have invigorating QI and tranquilization, the function of relieving cough and asthma, controls dizzy sleeplessness, shortness of breath and palpitation, asthenia cough with asthma because its nature and flavor are sweet.Select Endothelium Corneum Gigeriae Galli to be because its nature and flavor are sweet, flat, enter spleen, stomach warp, control stagnant, the function of strengthening the spleen and stomach, control food stagnation distension, vomiting regurgitation, dysentery, infantile malnutrition, quenches one's thirst, incontinence of urine, sore throat tonsillitis, ulcerative gingivitis aphtha.Select Rhizoma Cibotii to be because its property bitter but sweet flavor, temperature, enters liver, kidney channel, has invigorating the liver and kidney, and except rheumatism, strong waist foot, the function in sharp joint, controls back ache, gonalgia flaccidity of the lower limbs, cold-damp general arthralgia, loses and drowns, frequent micturition, seminal emission, leucorrhea.Select Rhizoma Paridis to be because its nature and flavor are bitter, be slightly cold, slightly poisonous, return Liver Channel, have heat-clearing and toxic substances removing, reducing swelling and alleviating pain, the function of cool liver arresting convulsion, controls furuncle carbuncle, laryngopharynx swelling and pain, venom, falls and flutter the pain of injury, convulsion with spasms.Select Spora Lygodii to be because its property slightly sweet flavor, cold, enter small intestinal, urinary bladder channel, have heat-clearing and toxic substances removing, the function of relieving stranguria by diuresis, controls urinary tract infection, lithangiuria, nebulousurine, leucorrhea, hepatitis, oedema due to nephritis, laryngopharynx swelling and pain, mumps, enteritis, dysentery, skin eczema, herpes zoster.Fructus Psoraleae is selected to be that temperature, enter kidney channel, have the function of reinforcing the kidney and supporting YANG, control cold diarrhea of suffering from a deficiency of the kidney, the enuresis, spermatorrhea, frequent micturition, sexual impotence, chills and pain of the waist and kness, deficiency and coldness is breathed heavily and coughed, external curing vitiligo because its nature and flavor are pungent.Select Polyporus to be because its property slightly sweet flavor, flat, enter spleen, kidney, urinary bladder channel, have the function of diuresis eliminating dampness by diuresis, control dysuria, edema distension, beriberi, has loose bowels, and drenches, turbid, leukorrhagia.Cortex Moutan is selected to be because its nature and flavor are worked hard, cool, enter the heart, liver, kidney channel, have heat clearing away, removing heat from blood, and blood, the function of repercussive, controls the pathogenic heat attacking blood system in febrile diseases, and send out speckle , Jing Epilepsy, tell, be defeated in battle, have blood in stool, hectic fever due to YIN-deficiency consumptive fever, amenorrhea , mass in the abdomen, carbuncle and ulcer, flutters damage.Gypsum Fibrosum is selected to be because its property acrid-sweet flavor, cold, enter lung, stomach warp, raw with there being expelling pathogenic factors from muscles for clearing heat, the function that relieving restlessness is quenched the thirst, controls calentura high fever and does not move back, vexed coma, delirium is gone mad, thirsty and dry pharynx, lung-heat dyspnea with rapid respiration, heatstroke spontaneous perspiration, stomach-fire headache, toothache, hyperactivity of toxic heat, send out speckle dermexanthesis, aphtha of the mouth and tongue, forges deposited promoting tissue regeneration and ulcer healing, external treatment ulcer sores, bursts and does not regain, the burning hot wound of soup.
Detailed description of the invention
The drug dose of instant component is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good therapeutic effect within the scope of following weight
Rhizoma Imperatae 10-20 gram of Herba Cirsii 10-20 gram of Cortex Lycii 5-15 gram
Radix Serissae 10-20 gram of Folium Pyrrosiae 10-20 gram of Herba Duchesneae Indicae 5-15 gram
Fructus Foeniculi 10-20 gram of Lumbricus 10-20 gram of Radix Paeoniae Rubra 5-15 gram
Folium Bambusae 10-20 gram of Folium Nelumbinis 10-20 gram of Radix Phytolaccae 5-15 gram
Radix Arnebiae (Radix Lithospermi) 10-20 gram of Semen Phaseoli 10-20 gram of Talcum 5-15 gram
Caulis Lonicerae 10-20 gram of Semen Armeniacae Amarum 10-20 gram of Bombyx Batryticatus 5-15 gram
Radix Carpesii 25-35 gram of Herba Violae 15-25 gram of Rhizoma Phragmitis 15-25 gram
Stigma Maydis 25-35 gram of Herba Pogostemonis 15-25 kairine sesame 15-25 gram
Endothelium Corneum Gigeriae Galli 25-35 gram of Rhizoma Cibotii 15-25 grammes per square metre building 15-25 gram
Spora Lygodii 10-20 gram of Fructus Psoraleae 10-20 gram of Polyporus 5-15 gram
Cortex Moutan 5-15 gram of Gypsum Fibrosum 15-25 gram
Preferable amount is
Rhizoma Imperatae 15 grams of Herba Cirsiis 15 grams of Cortex Lycii 10 grams
Radix Serissae 15 grams of Folium Pyrrosiaes 15 grams of Herba Duchesneae Indicaes 10 grams
Fructus Foeniculi 15 grams of Lumbricuss 15 grams of Radix Paeoniae Rubra 10 grams
Folium Bambusae 15 grams of Folium Nelumbinis 15 grams of Radix Phytolaccaes 10 grams
10 grams, Radix Arnebiae (Radix Lithospermi) 15 grams of Semen Phaseolis 15 grams of Talcums
Caulis Lonicerae 15 grams of Semen Armeniacae Amarums 15 grams of Bombyx Batryticatus 10 grams
Radix Carpesii 30 grams of Herba Violaes 20 grams of Rhizoma Phragmitiss 20 grams
Stigma Maydis 30 grams of Herba Pogostemonis 20 kairine sesames 20 grams
20 grams, Endothelium Corneum Gigeriae Galli 30 grams of Rhizoma Cibotii 20 grammes per square metre buildings
Spora Lygodii 15 grams of Fructus Psoraleaes 15 grams of Polyporus 10 grams
20 grams, Cortex Moutan 10 grams of Gypsum Fibrosum
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, Rhizoma Imperatae: pick clean impurity, clean, micro-profit, cutting, dries, clean chip of winnowing with a dustpan;
2, Herba Cirsii: pick clean impurity, remove root, washing runs through, tangent plane dries;
3, Cortex Lycii: pick decontamination and core, slightly wash, cutting, dry;
4, Radix Serissae: removing impurity, cleans, runs through, cutting, dry;
5, Folium Pyrrosiae: pick clean impurity, clean silt, outwash fine hair, cutting is dried;
6, Herba Duchesneae Indicae: pick clean impurity, dry;
7, Fructus Foeniculi: get crude drug, removing impurity;
8, Lumbricus: pick decontamination, rinses with water, pulls out in time, dries, cutting;
9, Radix Paeoniae Rubra: get crude drug, removing impurity, size stepping, cleans, runs through, shave, dry, and sieve removes chip;
10, Folium Bambusae: pick clean impurity, except destemming leaf, dries;
11, Folium Nelumbinis: clean with water, cut off the base of a fruit and edge, shredding, dry;
12, Radix Phytolaccae: clean, slightly soak, run through, section, dries;
13, Radix Arnebiae (Radix Lithospermi): clean, run through, section, dries;
14, Semen Phaseoli: get crude drug, removing impurity, the used time smashs to pieces;
15, Talcum: get crude drug, removing impurity, cleaning, drying;
16, Caulis Lonicerae: pick decontamination, is soaked in water, and runs through, and section, dries;
17, Semen Armeniacae Amarum: pick clean impurity, put in boiling water and slightly boil, the Pi Wei that waits purses up and pulls out, in leaching cold water, sloughs seed coat, dries, and winnows with a dustpan clean;
18, Bombyx Batryticatus: pick silk hair, cleans dirt, dries;
19, Radix Carpesii: pick clean impurity, dry;
20, Herba Violae: get crude drug, removing impurity, cleans, slightly dries in the air, cutting, dry;
21, Rhizoma Phragmitis: pick decontamination and root, cutting, dry;
22, Stigma Maydis: get crude drug, removing impurity, sieve dedust bits;
23, Herba Pogostemonis: pick decontamination, removing undesirable root and old stem, first taken by leaf and separately put, stem water runs through, and cutting is dried, then with leaf and even;
24, Ganoderma: removing impurity, cleans, softens, cut sheet, and dry, sieve removes chip;
25, Endothelium Corneum Gigeriae Galli: pick decontamination, rinses and dries;
26, Rhizoma Cibotii: get sand and put the interior stir-fry of pot to easily, add and pick clean Rhizoma Cibotii, fry to heaving and showing buff with high heat, take out, screen out sand, after wind dries in the air, hits or scraping Huang floss hair;
27, Rhizoma Paridis: removing fibrous root, cleaning, drying;
28, Spora Lygodii: get crude drug, crosses dusting cover, and sieve gets spore, removing impurity;
29, Fructus Psoraleae: clean impurity of winnowing with a dustpan, cleans, dries;
30, Polyporus: clean silt particle, soften section, dry;
31, Cortex Moutan: pick decontamination, removing core, cleans, runs through, and section, dries;
32, Gypsum Fibrosum: remove assorted stone, cleans earth, is broken into fritter.
Two, prepare
1, by the Rhizoma Imperatae of described weight, Herba Cirsii, Cortex Lycii, Radix Serissae, Folium Pyrrosiae, Herba Duchesneae Indicae, Fructus Foeniculi, Lumbricus, Radix Paeoniae Rubra, Folium Bambusae, Folium Nelumbinis, Radix Phytolaccae, Radix Arnebiae (Radix Lithospermi), Semen Phaseoli, Talcum, Caulis Lonicerae, Semen Armeniacae Amarum, Bombyx Batryticatus, Radix Carpesii, Herba Violae, Rhizoma Phragmitis, Stigma Maydis, Herba Pogostemonis, Ganoderma, Endothelium Corneum Gigeriae Galli, Rhizoma Cibotii, Rhizoma Paridis, Spora Lygodii, Fructus Psoraleae, Polyporus, Cortex Moutan, Gypsum Fibrosum medicine decocts with water secondary, add water 6 times amount for the first time, soak after 100 minutes, intense fire decocts boiling 10 minutes, use slow fire boiling again 40 minutes, filter first time decoction liquor, decoction liquor is poured in container.
2, add water the medicinal residues of filtration 4 times amount, and intense fire boils, then uses slow fire boiling 20 minutes, filters to obtain second time decoction liquor.
3, merge secondary decoction liquor, then with slow fire boiling 10 minutes and get final product, decoction liquor be divided into 4 doses to take.
Medicine of the present invention has relieving stranguria by diuresis, and lung heat clearing expels the heat-evil, and the function of heat-clearing and toxic substances removing, is used for the treatment of pyelonephritis, short treating period, instant effect, has no side effect.
Set forth the beneficial effect of medicine of the present invention further below by way of test example, these test examples include animal toxicity test report and the clinical observation material of medicine of the present invention.
The animal toxicity test report of [test example 1] medicine of the present invention
Get rabbit 30, male and female dual-purpose, body weight 2.0-2.4kg, divide two groups, often organize 15, wherein one group is overdose test group, and another group is normal amount test group.Super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is administration by gavage administration, every day 2 times, serve on 7 days, observes administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.
The observations of [test example 2] Drug therapy pyelonephritis of the present invention
1, physical data
Accept pyelonephritis patient totally 184 examples for medical treatment.
2, diagnostic criteria
Clinical manifestation:
Primary disease can betide the various age, but the most common with the women of child-bearing age, and onset is hurried, mainly contains following symptoms
(1) general symptom
High heat, shiver with cold, body temperature is many between 38 ~ 39 DEG C, also can up to 40 DEG C.Pattern of fever differs, general in tension and relaxation type, also in interval or can delay type.Companioned with headache, systemic pain, profuse sweating etc. when heat is moved back.
(2) urinary system symptom
Patient has lumbago, mostly is dull pain or aches, degree varies, minority has abdominal colic, radiate along defeated ureter to bladder direction, have tenderness during health check-up at upper ureter point (rectus abdominis m. outer rim and umbilicus horizontal line cross point) or costolumbar point (psoas major outer rim and 12 rib cross points), it is positive that kidney kowtows pain.Patient often has the irritations sign of bladder such as frequent micturition, urgent micturition, dysurea.The urinary system system symptom of child patient is often not obvious, during onset except the General Symptomies such as high heat, often has convulsions, convulsive seizure.
(3) gastrointestinal symptom
Can have inappetence, Nausea and vomiting, few patients can have middle upper abdomen or full abdomen pain.Acute pyelonephritis treatment not in time, can transfer chronic pyelonephritis to, the easy recurrent exerbation of chronic pyelonephritis, and comparatively acute stage gently, can show as silent urine to symptom sometimes.Patient more than half has acute pyelonephritis history of past illness, has thereafter weak, low grade fever, anorexia and soreness of waist lumbago shape, and with lower urinary tract irritations such as frequent micturition, urgent micturition, dysureas.Occur when acute attack shows also.The course of disease was exceeded half a year or 1 year person for chronic pyelonephritis, proposing renal pelvis renal calices in recent years has cicatrization in the past, and intravenous urography sees the distortion of renal pelvis renal calices, hydrops, kidney profile are rough, or two inequality in size of kidneys just claim chronic pyelonephritis.Can have renal tubulounterstitial function injure, as concentrating function goes down, hypotonic, low-gravity urine, nocturia increases and renal tubular acidosis etc.To late period, can occur that glomerular function damages, azotemia is until uremia.Renal hypertension is much caused by chronic pyelitis, it is generally acknowledged that the release of patient's high-renin mass formed by blood stasis and some vasoconstrictive polypeptide and sclerosis of blood vessels, the pathological changes such as narrow are relevant.After the sick kidney in small number of patients excision side, hypertension is improved.
3, Therapeutic Method
Select above-mentioned medicament, take to patient, each serving with 1 dose, every day is early, middle and late respectively takes 1 time, within 7 days, is a course for the treatment of, takes 8 courses for the treatment of continuously.
4, efficacy assessment standard
Effective: pyelonephritis transference cure, observe half a year without bounce-back person;
Take a turn for the better: pyelonephritis symptom is obviously improved, and body constitution progressively strengthens;
Invalid: pyelonephritis symptom, without change, does not reach improvement standard person.
5, therapeutic outcome (seeing the following form)
In above-mentioned treatment, by Drug therapy pyelonephritis patient 184 example of the present invention, effective 175 examples of result, obvious effective rate is 95.11%, and take a turn for the better 6 examples, and improvement rate is 3.26%, and invalid 3 examples, total effective rate is 98.37%.

Claims (3)

1. treat a medicine for pyelonephritis, it is characterized in that: it is made up of the crude drug in following weight range:
Rhizoma Imperatae 10-20 gram of Herba Cirsii 10-20 gram of Cortex Lycii 5-15 gram
Radix Serissae 10-20 gram of Folium Pyrrosiae 10-20 gram of Herba Duchesneae Indicae 5-15 gram
Fructus Foeniculi 10-20 gram of Lumbricus 10-20 gram of Radix Paeoniae Rubra 5-15 gram
Folium Bambusae 10-20 gram of Folium Nelumbinis 10-20 gram of Radix Phytolaccae 5-15 gram
Radix Arnebiae (Radix Lithospermi) 10-20 gram of Semen Phaseoli 10-20 gram of Talcum 5-15 gram
Caulis Lonicerae 10-20 gram of Semen Armeniacae Amarum 10-20 gram of Bombyx Batryticatus 5-15 gram
Radix Carpesii 25-35 gram of Herba Violae 15-25 gram of Rhizoma Phragmitis 15-25 gram
Stigma Maydis 25-35 gram of Herba Pogostemonis 15-25 kairine sesame 15-25 gram
Endothelium Corneum Gigeriae Galli 25-35 gram of Rhizoma Cibotii 15-25 grammes per square metre building 15-25 gram
Spora Lygodii 10-20 gram of Fructus Psoraleae 10-20 gram of Polyporus 5-15 gram
Cortex Moutan 5-15 gram of Gypsum Fibrosum 15-25 gram.
2. medicine according to claim 1, wherein the consumption of each crude drug is:
Rhizoma Imperatae 15 grams of Herba Cirsiis 15 grams of Cortex Lycii 10 grams
Radix Serissae 15 grams of Folium Pyrrosiaes 15 grams of Herba Duchesneae Indicaes 10 grams
Fructus Foeniculi 15 grams of Lumbricuss 15 grams of Radix Paeoniae Rubra 10 grams
Folium Bambusae 15 grams of Folium Nelumbinis 15 grams of Radix Phytolaccaes 10 grams
10 grams, Radix Arnebiae (Radix Lithospermi) 15 grams of Semen Phaseolis 15 grams of Talcums
Caulis Lonicerae 15 grams of Semen Armeniacae Amarums 15 grams of Bombyx Batryticatus 10 grams
Radix Carpesii 30 grams of Herba Violaes 20 grams of Rhizoma Phragmitiss 20 grams
Stigma Maydis 30 grams of Herba Pogostemonis 20 kairine sesames 20 grams
20 grams, Endothelium Corneum Gigeriae Galli 30 grams of Rhizoma Cibotii 20 grammes per square metre buildings
Spora Lygodii 15 grams of Fructus Psoraleaes 15 grams of Polyporus 10 grams
20 grams, Cortex Moutan 10 grams of Gypsum Fibrosum.
3. the preparation method of medicine according to claim 1 or 2, is characterized in that: it comprises the following steps:
(1) get the raw materials ready
(1) Rhizoma Imperatae: pick clean impurity, clean, micro-profit, cutting, dries, clean chip of winnowing with a dustpan;
(2) Herba Cirsii: pick clean impurity, remove root, washing runs through, tangent plane dries;
(3) Cortex Lycii: pick decontamination and core, slightly wash, cutting, dry;
(4) Radix Serissae: removing impurity, cleans, runs through, cutting, dry;
(5) Folium Pyrrosiae: pick clean impurity, clean silt, outwash fine hair, cutting is dried;
(6) Herba Duchesneae Indicae: pick clean impurity, dry;
(7) Fructus Foeniculi: get crude drug, removing impurity;
(8) Lumbricus: pick decontamination, rinses with water, pulls out in time, dries, cutting;
(9) Radix Paeoniae Rubra: get crude drug, removing impurity, size stepping, cleans, runs through, shave, dry, and sieve removes chip;
(10) Folium Bambusae: pick clean impurity, except destemming leaf, dries;
(11) Folium Nelumbinis: clean with water, cut off the base of a fruit and edge, shredding, dry;
(12) Radix Phytolaccae: clean, slightly soak, run through, section, dries;
(13) Radix Arnebiae (Radix Lithospermi): clean, run through, section, dries;
(14) Semen Phaseoli: get crude drug, removing impurity, the used time smashs to pieces;
(15) Talcum: get crude drug, removing impurity, cleaning, drying;
(16) Caulis Lonicerae: pick decontamination, is soaked in water, and runs through, and section, dries;
(17) Semen Armeniacae Amarum: pick clean impurity, put in boiling water and slightly boil, the Pi Wei that waits purses up and pulls out, in leaching cold water, sloughs seed coat, dries, and winnows with a dustpan clean;
(18) Bombyx Batryticatus: pick silk hair, cleans dirt, dries;
(19) Radix Carpesii: pick clean impurity, dry;
(20) Herba Violae: get crude drug, removing impurity, cleans, slightly dries in the air, cutting, dry;
(21) Rhizoma Phragmitis: pick decontamination and root, cutting, dry;
(22) Stigma Maydis: get crude drug, removing impurity, sieve dedust bits;
(23) Herba Pogostemonis: pick decontamination, removing undesirable root and old stem, first taken by leaf and separately put, stem water runs through, and cutting is dried, then with leaf and even;
(24) Ganoderma: removing impurity, cleans, softens, cut sheet, and dry, sieve removes chip;
(25) Endothelium Corneum Gigeriae Galli: pick decontamination, rinses and dries;
(26) Rhizoma Cibotii: get sand and put the interior stir-fry of pot to easily, add and pick clean Rhizoma Cibotii, fry to heaving and showing buff with high heat, take out, screen out sand, after wind dries in the air, hits or scraping Huang floss hair;
(27) Rhizoma Paridis: removing fibrous root, cleaning, drying;
(28) Spora Lygodii: get crude drug, crosses dusting cover, and sieve gets spore, removing impurity;
(29) Fructus Psoraleae: clean impurity of winnowing with a dustpan, cleans, dries;
(30) Polyporus: clean silt particle, soften section, dry;
(31) Cortex Moutan: pick decontamination, removing core, cleans, runs through, and section, dries;
(32) Gypsum Fibrosum: remove assorted stone, cleans earth, is broken into fritter;
(2) prepare
(1) by the Rhizoma Imperatae of described weight, Herba Cirsii, Cortex Lycii, Radix Serissae, Folium Pyrrosiae, Herba Duchesneae Indicae, Fructus Foeniculi, Lumbricus, Radix Paeoniae Rubra, Folium Bambusae, Folium Nelumbinis, Radix Phytolaccae, Radix Arnebiae (Radix Lithospermi), Semen Phaseoli, Talcum, Caulis Lonicerae, Semen Armeniacae Amarum, Bombyx Batryticatus, Radix Carpesii, Herba Violae, Rhizoma Phragmitis, Stigma Maydis, Herba Pogostemonis, Ganoderma, Endothelium Corneum Gigeriae Galli, Rhizoma Cibotii, Rhizoma Paridis, Spora Lygodii, Fructus Psoraleae, Polyporus, Cortex Moutan, Gypsum Fibrosum medicine decocts with water secondary, add water 6 times amount for the first time, soak after 100 minutes, intense fire decocts boiling 10 minutes, use slow fire boiling again 40 minutes, filter first time decoction liquor, decoction liquor is poured in container,
(2) add water the medicinal residues of filtration 4 times amount, and intense fire boils, then uses slow fire boiling 20 minutes, filters to obtain second time decoction liquor;
(3) secondary decoction liquor is merged, then with slow fire boiling 10 minutes and get final product.
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CN101204481A (en) * 2007-12-17 2008-06-25 牟培超 Chinese traditional medicine for chronic nephritis
CN101670055A (en) * 2009-10-30 2010-03-17 泰一和浦(北京)中医药研究院有限公司 Traditional Chinese medicine composition for treating disease of pyelonephritis and preparation method

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CN101204481A (en) * 2007-12-17 2008-06-25 牟培超 Chinese traditional medicine for chronic nephritis
CN101670055A (en) * 2009-10-30 2010-03-17 泰一和浦(北京)中医药研究院有限公司 Traditional Chinese medicine composition for treating disease of pyelonephritis and preparation method

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