CN102772780B - Medicament for treating ahypnosis and preparation method thereof - Google Patents
Medicament for treating ahypnosis and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a medicament for treating ahypnosis and a preparation method thereof. The medicament is mainly prepared from pinellia ternate, immature orange fruit, liquorice, ginger, Chinese date, dwarf lilyturf tuber, ladybell root, honeysuckle, uncaria rhynchophylla, tuber fleeceflower stem, fossil fragment and pearl in a certain weight proportion. The medicament has the functions of tonifying yin and nourishing blood, invigorating spleen and moistening dryness, and calming and tranquilizing mind, and has the advantages of quick response, short treatment course and high heal rate in treating ahypnosis.
Description
Technical field
The present invention relates to medicine of a kind of Cure for insomnia and preparation method thereof, belong to the field of Chinese medicines.
Technical background
Insomnia refers to fall asleep and maybe cannot keep sleep state, causes not having enough sleep, has a sleepless night also known as DIMS (DlMS), be a kind of commonly encountered diseases, show as difficulty falling asleep, intermittently discontinuous, and wake up prematurely, can not continue again to sleep after waking up, malaise, asthenia is felt, pain, do not feel like oneself, circadian rhythm is upset, and insomnia have impact on people's daily life and work.At present, Western medicine cannot effective Cure for insomnia, and long-term taking Western medicine has a lot of side effect, and therefore, people exist very large demand to the Chinese medicine of effective Cure for insomnia.
Summary of the invention
The present inventor, according to the research of theory of Chinese medical science and clinical test repeatedly and checking, finally have found the medicine of effective Cure for insomnia, thus completes the present invention.
Object of the present invention be just to provide a kind of can the composition of medicine of Cure for insomnia.
Another object of the present invention just there is provided the preparation method of this composition of medicine.
Medicine of the present invention selects the Rhizoma Pinelliae, Pericarpium Citri Reticulatae, Caulis Bambusae In Taenia, Poria, Fructus Aurantii Immaturus, Radix Glycyrrhizae, Rhizoma Zingiberis Recens, Fructus Jujubae, Radix Ophiopogonis, Radix Adenophorae, Flos Lonicerae, Radix Rehmanniae, the Rhizoma Atractylodis Macrocephalae, Pericarpium Citri Reticulatae, Radix Codonopsis, Rhizoma Cimicifugae, Radix Bupleuri, Ramulus Uncariae Cum Uncis, Radix Salviae Miltiorrhizae, Spica Prunellae, Cortex Albiziae, Caulis Polygoni Multiflori, Os Draconis and Concha Margaritifera crude drug to combine, each efficacy of drugs is made by these drug regimens to produce synergism, thus can effective Cure for insomnia.Wherein select the Rhizoma Pinelliae to be because its nature and flavor are pungent, temperature, poisonous, enter spleen, stomach warp, have drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, the function of clear painful abdominal mass eliminating stagnation, control the vomiting of damp-phlegm cold drink, regurgitation, cough with asthma abundant expectoration, my diaphragm distension, syncope due to accumulation of phlegm is had a headache, dizzy sleeplessness, outer subduing inflammation.Pericarpium Citri Reticulatae is selected to be that temperature, return lung, spleen channel, have regulating qi-flowing for strengthening spleen, the function of drying dampness to eliminate phlegm, controls fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm because its nature and flavor are bitter, pungent.Select Caulis Bambusae In Taenia to be because its nature and flavor are sweet, cool, enter stomach, gallbladder meridian, have heat clearing away, removing heat from blood, reduce phlegm, the function of emesis, control dysphoria with smothery sensation vomiting, singultus, expectorant heat syndrome cough is breathed heavily, and spits blood, epistaxis, metrorrhagia, malignant histocytosis, fetal movement ， Jing Epilepsy.Select Poria to be because its property slightly sweet flavor, flat, enter the heart, spleen, lung meridian, have eliminating dampness and diuresis, strengthening the spleen stomach function regulating, the function of mind tranquilizing and the heart calming, control dysuria edema distending pain, phlegm retention cough with dyspnea, the sound of vomiting of vomitting, has loose bowels, seminal emission, stranguria with turbid discharge, and palpitation with fear is forgetful.Select Fructus Aurantii Immaturus to be because its nature and flavor are bitter, cold, enter spleen, stomach warp, have dispelling the stagnated QI, loose painful abdominal mass, rush down expectorant, the function of removing food stagnancy, controls chest and abdomen swelling and pain, the thoracic obstruction, painful abdominal mass pain, accumulation of phlegm in the hypochondrium, edema, food stagnation, constipation, gastroptosis, uterine prolapse, proctoptosis.Radix Glycyrrhizae is selected to be because its nature and flavor are sweet, flat, enter spleen, stomach, lung meridian, have and middle emergency, lung moistening, removing toxic substances, the function of coordinating the actions of various ingredients in a prescription; Process use, control taste lack of appetite, stomachache loose stool, overstrain generates heat, and consumptive lung disease is coughed, cardiopalmus ， Jing Epilepsy; Raw use, controls laryngopharynx swelling and pain, peptic ulcer, carbuncle subcutaneous ulcer skin infection, separates poison of drug and alimentary toxicosis.Select Rhizoma Zingiberis Recens to be because its nature and flavor are pungent, temperature, enter lung, stomach, spleen channel, deliver, cold expelling, preventing or arresting vomiting, open the function of expectorant, cure cold wind and cold, vomiting, and phlegm retention, breathes with cough, and distension is had loose bowels, and separates the Rhizoma Pinelliae, Rhizoma Arisaematis and fish Eriocheir sinensis, birds and beasts meat poisoning.Select Fructus Jujubae to be that temperature, enters spleen, stomach warp, have spleen reinforcing stomach function regulating, supplementing QI for promoting the production of body fluid because its nature and flavor are sweet, adjust battalion to defend, separate the function of poison of drug, control insufficiency of stomach lack of appetite, the weak loose stool of spleen, qi-blood-body fluid is not enough, disharmony of nutrient QI with defensive QI, severe palpitation, woman hysteria.Select be because its property sweet and slightly bitter taste Radix Ophiopogonis, cold, enter lung, stomach, heart channel, have nourishing YIN and moistening the lung, clear away heart-fire relieving restlessness, and the function of reinforcing stomach reg fluid controls dryness of the lung dry cough, spits blood, spitting of blood, consumptive lung disease, lung abscess, asthenia dysphoria with smothery sensation, and clearly yearningly, calentura Tianjin is hindered, dry mouth and throat, constipation.Select Radix Adenophorae to be that be slightly cold, attach to the lung and stomach meridians, have nourishing YIN and clearing away lung-heat, reduce phlegm, the function of QI invigorating, controls lung-heat type cough, deficiency of YIN phthisical cough because its nature and flavor are sweet, dry cough expectorant sticks, deficiency of both vital energy and Yin, restlessness and fever with thirst.Flos Lonicerae is selected to be because its nature and flavor are sweet, cold, enter lung, stomach warp, have heat clearing away, the function of removing toxic substances, control epidemic febrile disease heating, toxic-heat and blood stasis, carbuncle and ulcer, toxic swelling, scrofula, anal fistula.Select Radix Rehmanniae to be that cold, GUIXIN, liver, kidney channel, have clearing away heat and cooling blood, yin nourishing, the function of promoting the production of body fluid, and controls calentura excessive thirst, yin asthenia generating intrinsic heat, hectic fever due to YIN-deficiency consumptive fever, and interior-heat is quenched one's thirst because its nature and flavor are sweet, spit blood, epistaxis, sends out speckle dermexanthesis.Select the Rhizoma Atractylodis Macrocephalae to be because its property bitter but sweet flavor, temperature, enters spleen, stomach warp, has spleen reinforcing, stomach reinforcing, dampness, and in function, control deficient QI of the spleen and stomach, anorexia, asthenia weak breath, deficiency-distension, has loose bowels, phlegm retention, edema, jaundice, arthralgia chiefly caused by damp pathogen, dysuria, dizzy, spontaneous perspiration, and nausea is uneasy.Pericarpium Citri Reticulatae is selected to be that temperature, return lung, spleen channel, have regulating qi-flowing for strengthening spleen, the function of drying dampness to eliminate phlegm, controls fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm because its nature and flavor are bitter, pungent.Select Radix Codonopsis to be because its nature and flavor are sweet, flat, start with, meridian of Foot-TAI YIN edema caused by disorder of QI, have invigorating the spleen and replenishing QI, the function of promoting the production of body fluid, controls weakness of the spleen and stomach, deficiency of both QI and blood, fatigue and lack of strength, and lack of appetite is thirsty, chronic diarrhea, proctoptosis.Rhizoma Cimicifugae is selected to be because the sweet pungent micro-hardship of its nature and flavor, cool, enter lung, spleen, stomach warp, have yang invigorating, deliver, rash, the function of removing toxic substances, controls seasonal epidemic pathogens epidemic disease labor, headache cold and heat, laryngalgia, aphtha scar, and macule is not saturating, sinking of QI of middle-JIAO, chronic diarrhea chronic dysentery, proctoptosis, women's metrorrhagia and leukorrhagia, uterus drops, carbuncle sore tumefacting virus.Select Radix Bupleuri to be that cool, enter liver, gallbladder meridian, have reconciling superficies and interior, soothing the liver, the function of yang invigorating, controls alternate attack of chill and fever, fullness in the chest and hypochondriac pain because its nature and flavor are bitter, bitter taste is deaf, headache and dizziness, malaria, lower sharp proctoptosis, menoxenia, uterine prolapse.Select Ramulus Uncariae Cum Uncis to be because its nature and flavor are bitter, cool, enter liver, heart channel, have heat clearing away suppressing the hyperactive liver, the function of the arresting convulsion that relieves dizziness, high fever, infantile convulsions, epilepsy, etc., controls little Jing Epilepsy Chi Zong, adult's slight Hypertension, dizzy, dizzy, married woman's eclampsia.Radix Salviae Miltiorrhizae is selected to be that tepor, enters the heart, Liver Channel, have blood circulation and promoting silt, calming heart and tranquilizing mind, evacuation of pus, and the function of pain relieving, controls angina cordis, menoxenia, dysmenorrhea, and to close, metrorrhagia leukorrhagia ， mass in the abdomen, gathers, abdominal pain due to blood stasis, arthralgia because its nature and flavor are bitter, palpitation with fear sleeplessness, malignant boil toxic swelling.Select Spica Prunellae to be because its nature and flavor toil, cold, enter liver, gallbladder meridian, have liver heat removing, the function of eliminating stagnation, controls scrofula, goiter, acute mastitis, breast carcinoma, order pearl nyctalgia, photophobia is shed tears, the vertigo, facial hemiparalysis, bones and muscles pain, pulmonary tuberculosis, acute icteric infectious hepatitis, metrorrhagia, leukorrhagia.Cortex Albiziae is selected to be because its nature and flavor are sweet, flat, enter the heart, Liver Channel, have resolving depression, and blood, mind calming, the function of subduing inflammation, controls irritability, melancholy insomnia, lung abscess, carbuncle, scrofula, injured bone.Select Caulis Polygoni Multiflori to be because its property sweet and slightly bitter taste, flat, enter the heart, Liver Channel, nourish heart, calm the nerves, dredging collateral, the function of dispeling the wind, controls insomnia, impairment caused by overstrain, hyperhidrosis, blood deficiency general pain, carbuncle, scrofula, wind skin ulcer scabies.Select Os Draconis to be because its property sweet-puckery flavor, flat, be included into the heart, liver, kidney, large intestine channel, have tranquillizing the mind by relieving convulsion, the function of arresting sweating controlling nocturnal emission with astringent drugs, control frightened Epilepsy demented, palpitation with a distress feeling is forgetful, insomnia and dreamful sleep, spontaneous sweating.Select Concha Margaritifera to be because its nature and flavor are salty, cool, enter the heart, liver two warp, have suppressing the hyperactive liver, YANG hyperactivity suppressing, arresting convulsion, the function of hemostasis, controls dizziness, tinnitus, cardiopalmus, insomnia, and demented ， Jing Epilepsy is spitted blood, epistaxis, metrorrhagia.
Detailed description of the invention
The drug dose of the present invention's combination is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good therapeutic effect within the scope of following weight
Rhizoma Pinelliae 8-15 gram of Pericarpium Citri Reticulatae 10-20 gram of Caulis Bambusae In Taenia 6-10 gram
Poria 8-15 gram of Fructus Aurantii Immaturus 10-20 gram of Radix Glycyrrhizae 10-15 gram
Rhizoma Zingiberis Recens 6-10 gram Fructus Jujubae 15-25 gram Radix Ophiopogonis 8-15 gram
Radix Adenophorae 10-18 gram of Flos Lonicerae 8-12 gram of Radix Rehmanniae 8-12 gram
Rhizoma Atractylodis Macrocephalae 10-20 gram of Pericarpium Citri Reticulatae 10-20 gram of Radix Codonopsis 8-12 gram
Rhizoma Cimicifugae 10-20 gram of Radix Bupleuri 10-15 gram of Ramulus Uncariae Cum Uncis 10-20 gram
Radix Salviae Miltiorrhizae 8-12 gram of Spica Prunellae 10-15 gram of Cortex Albiziae 10-20 gram
Caulis Polygoni Multiflori 8-12 cron bone 8-12 gram of Concha Margaritifera 15-25 gram
Wherein, be preferably
The Rhizoma Pinelliae 10 grams of Pericarpium Citri Reticulataes 15 grams of Caulis Bambusae In Taenia 8 grams
12 grams, Poria 10 grams of Fructus Aurantii Immaturuss 15 grams of Radix Glycyrrhizaes
Rhizoma Zingiberis Recens 8 grams of Fructus Jujubaes 20 grams of Radix Ophiopogonis 12 grams
Radix Adenophorae 15 grams of Flos Loniceraes 10 grams of Radix Rehmanniae 10 grams
The Rhizoma Atractylodis Macrocephalae 15 grams of Pericarpium Citri Reticulataes 15 grams of Radix Codonopsis 10 grams
Rhizoma Cimicifugae 15 grams of Radix Bupleuri 12 grams of Ramulus Uncariae Cum Uncis 15 grams
Radix Salviae Miltiorrhizae 10 grams of Spica Prunellaes 12 grams of Cortex Albiziaes 15 grams
Caulis Polygoni Multiflori 10 cron bone 10 grams of Concha Margaritiferas 20 grams
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, the Rhizoma Pinelliae: pick decontamination, sieve dedust bits;
2, Pericarpium Citri Reticulatae: get crude drug, the peel of removing impurity and blackening, wash quickly is clean, softens, shredding, dries or cold drying, sieve dedust bits;
3, Caulis Bambusae In Taenia: remove hard bamboo let, impurity, shakes off ash bits, is kneaded into little group or cutting;
4, Poria: be soaked in water, cleans and pulls out, and after vexed, section, dries;
5, Fructus Aurantii Immaturus: pick clean impurity, be soaked in water to eighty per cant thoroughly, pull out, profit, to interior without hard-core, cut into slices, is dried;
6, Radix Glycyrrhizae: pick decontamination, cleans, and when being soaked in water saturating to eighty per cant, pulling out, runs through section, dry;
7, Rhizoma Zingiberis Recens: pick decontamination, cleans earth, and the used time cuts into slices;
8, Fructus Jujubae: pick clean impurity, dry;
9, Radix Ophiopogonis: pick clean impurity, be soaked in water, pull out, pump the heart after running through, then clean dry;
10, Radix Adenophorae: removing fibrous root, cleans, scrapes off rough bark, dry;
11, Flos Lonicerae: sieve removes silt, picks clean impurity;
12, Radix Rehmanniae: get crude drug, removing impurity, cleans, slightly moistens, cut sheet, dry, and sieve removes chip;
13, the Rhizoma Atractylodis Macrocephalae: pick clean impurity, be soaked in water, pull out after bubble, run through, section, dries;
14, Pericarpium Citri Reticulatae: get crude drug, the peel of removing impurity and blackening, wash quickly is clean, softens, shredding, dries or cold drying, sieve dedust bits;
15, Radix Codonopsis: run through reed after cleaning silt, section or cutting, dry;
16, Rhizoma Cimicifugae: pick decontamination, slightly foam washing is clean, pulls out, runs through, and section, dries;
17, Radix Bupleuri: pick decontamination, removes residual stem, cleans silt, pulls out, run through rear timely section, dry immediately;
18, Ramulus Uncariae Cum Uncis: pick old stalk, impurity, cleans, dries;
19, Radix Salviae Miltiorrhizae: pick clean impurity, removing rhizome, cleans, pulls out, run through rear section, dry;
20, Spica Prunellae: get crude drug, except discarding stalk, blade and impurity, sieve dedust bits;
21, Cortex Albiziae: clear water soaks to be cleaned, and pulls out, is first divided into equal greatly rectangular after moistening, then stripping and slicing or shredding, dry;
22, Caulis Polygoni Multiflori: clear water is cleaned, and slightly soak, pull out, after running through, cutting, dries;
23, Os Draconis: outwash earth, smash;
24, Concha Margaritifera: pick decontamination, knock fragment, sieve dedust bits.
Two, prepare
1, the Rhizoma Pinelliae of described weight, Pericarpium Citri Reticulatae, Caulis Bambusae In Taenia, Poria, Fructus Aurantii Immaturus, Radix Glycyrrhizae, Rhizoma Zingiberis Recens, Fructus Jujubae, Radix Ophiopogonis, Radix Adenophorae, Flos Lonicerae, Radix Rehmanniae, the Rhizoma Atractylodis Macrocephalae, Pericarpium Citri Reticulatae, Radix Codonopsis, Rhizoma Cimicifugae, Radix Bupleuri, Ramulus Uncariae Cum Uncis, Radix Salviae Miltiorrhizae, Spica Prunellae, Cortex Albiziae, Caulis Polygoni Multiflori, Os Draconis, Concha Margaritifera are decocted with water, add water 4 times amount for the first time, soak 60 minutes, intense fire decocts boiling, use slow fire boiling again 30 minutes, obtain first time decoction liquor.
2, add water medicinal residues after first time filtration 2 times amount, decocts boiling, then within 20 minutes, namely obtain second time decoction liquor with slow fire boiling.
3, by twice decoction liquor mixing, 3 doses are divided into take.
Medicine of the present invention has nourishing YIN and benefiting blood, and spleen reinforcing is moisturized, effect of mind tranquilizing and the heart calming, Cure for insomnia instant effect, and good effect, cure rate is high.
Set forth the beneficial effect of medicine of the present invention further below by way of test example, these tests comprise animal toxicity test and the clinical observation test of medicine of the present invention.
The animal toxicity test report of [test example 1] medicine of the present invention:
Get rabbit 40, male and female dual-purpose, body weight 2.0-2.5kg, divide two groups, often organize 20, wherein one group is overdose test group, and another group is normal amount test group.Super quantity group is 30ml/kg, and normal amount is 10ml/kg, and administering mode is administration by gavage administration, twice daily, serve on 7 days, observes administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.
The clinical observation material of [test example 2] medicine of the present invention
1, physical data
Accept out-patient 200 example for medical treatment, wherein 30-35 years old 60 age example, 36-40 years old 85 example, 41-50 years old 55 example.
2, diagnostic criteria
Insomnia clinical manifestation is:
1. the phase is slipped in sleep: time for falling asleep is no more than 30 minutes;
2. to sleep maintenance: number of times of awakening night more than 6 times or morning early awakening;
3. sleep quality: many bad dreams;
4. total length of one's sleep is less than 6 hours;
5. residual effect in the daytime: feel dizzy secondary morning, lassitude, drowsiness, weak etc.
3, Therapeutic Method
Select above-mentioned medicament, take to patient, each serving with 1 dose, every day is early, middle and late respectively takes 1 time, within 7 days, is a course for the treatment of, takes 5 courses for the treatment of continuously.
4, efficacy assessment standard
Effective: clinical symptom disappearance after treatment, sleep recovers normal, observes half a year without recidivist;
Take a turn for the better: clinical symptoms is obviously improved, and sleep quality progressively recovers;
Invalid: clinical part transference cure or without change, do not reach improvement standard person.
5, therapeutic outcome
In above-mentioned treatment, by Drug therapy insomniac 200 example of the present invention, effective 190 examples of result, obvious effective rate is 95%, and take a turn for the better 8 examples, and improvement rate is 4%, and invalid 2 examples, total effective rate is 99%.
Claims (3)
1. a medicine for Cure for insomnia, is characterized in that: it is made up of the crude drug within the scope of following weight:
Rhizoma Pinelliae 8-15 gram of Pericarpium Citri Reticulatae 10-20 gram of Caulis Bambusae In Taenia 6-10 gram
Poria 8-15 gram of Fructus Aurantii Immaturus 10-20 gram of Radix Glycyrrhizae 10-15 gram
Rhizoma Zingiberis Recens 6-10 gram Fructus Jujubae 15-25 gram Radix Ophiopogonis 8-15 gram
Radix Adenophorae 10-18 gram of Flos Lonicerae 8-12 gram of Radix Rehmanniae 8-12 gram
Rhizoma Atractylodis Macrocephalae 10-20 gram of Radix Codonopsis 8-12 gram liter fiber crops 10-20 gram
Radix Bupleuri 10-15 gram of Ramulus Uncariae Cum Uncis 10-20 gram of Radix Salviae Miltiorrhizae 8-12 gram
Spica Prunellae 10-15 gram of Cortex Albiziae 10-20 gram of Caulis Polygoni Multiflori 8-12 gram
Os Draconis 8-12 gram of Concha Margaritifera 15-25 gram of Pericarpium Citri Reticulatae 10-20 gram;
Preparation method is as follows:
(1) get the raw materials ready
(1) Rhizoma Pinelliae: pick decontamination, sieve dedust bits;
(2) Pericarpium Citri Reticulatae: get crude drug, the peel of removing impurity and blackening, wash quickly is clean, softens, shredding, dries or cold drying, sieve dedust bits;
(3) Caulis Bambusae In Taenia: remove hard bamboo let, impurity, shakes off ash bits, is kneaded into little group or cutting;
(4) Poria: be soaked in water, cleans and pulls out, and after vexed, section, dries;
(5) Fructus Aurantii Immaturus: pick clean impurity, be soaked in water to eighty per cant thoroughly, pull out, profit, to interior without hard-core, cut into slices, is dried;
(6) Radix Glycyrrhizae: pick decontamination, cleans, and when being soaked in water saturating to eighty per cant, pulling out, runs through section, dry;
(7) Rhizoma Zingiberis Recens: pick decontamination, cleans earth, and the used time cuts into slices;
(8) Fructus Jujubae: pick clean impurity, dry;
(9) Radix Ophiopogonis: pick clean impurity, be soaked in water, pull out, pump the heart after running through, then clean dry;
(10) Radix Adenophorae: removing fibrous root, cleans, scrapes off rough bark, dry;
(11) Flos Lonicerae: sieve removes silt, picks clean impurity;
(12) Radix Rehmanniae: get crude drug, removing impurity, cleans, slightly moistens, cut sheet, dry, and sieve removes chip;
(13) Rhizoma Atractylodis Macrocephalae: pick clean impurity, be soaked in water, pull out after bubble, run through, section, dries;
(14) Radix Codonopsis: run through reed after cleaning silt, section or cutting, dry;
(15) Rhizoma Cimicifugae: pick decontamination, slightly foam washing is clean, pulls out, runs through, and section, dries;
(16) Radix Bupleuri: pick decontamination, removes residual stem, cleans silt, pulls out, run through rear timely section, dry immediately;
(17) Ramulus Uncariae Cum Uncis: pick old stalk, impurity, cleans, dries;
(18) Radix Salviae Miltiorrhizae: pick clean impurity, removing rhizome, cleans, pulls out, run through rear section, dry;
(19) Spica Prunellae: get crude drug, except discarding stalk, blade and impurity, sieve dedust bits;
(20) Cortex Albiziae: clear water soaks to be cleaned, and pulls out, is first divided into equal greatly rectangular after moistening, then stripping and slicing or shredding, dry;
(21) Caulis Polygoni Multiflori: clear water is cleaned, and slightly soak, pull out, after running through, cutting, dries;
(22) Os Draconis: outwash earth, smash;
(23) Concha Margaritifera: pick decontamination, knock fragment, sieve dedust bits;
(24) Pericarpium Citri Reticulatae: get crude drug, the peel of removing impurity and blackening, wash quickly is clean, softens, shredding, dries or cold drying, sieve dedust bits;
(2) prepare
(1) Rhizoma Pinelliae of described weight, Pericarpium Citri Reticulatae, Caulis Bambusae In Taenia, Poria, Fructus Aurantii Immaturus, Radix Glycyrrhizae, Rhizoma Zingiberis Recens, Fructus Jujubae, Radix Ophiopogonis, Radix Adenophorae, Flos Lonicerae, Radix Rehmanniae, the Rhizoma Atractylodis Macrocephalae, Radix Codonopsis, Rhizoma Cimicifugae, Radix Bupleuri, Ramulus Uncariae Cum Uncis, Radix Salviae Miltiorrhizae, Spica Prunellae, Cortex Albiziae, Caulis Polygoni Multiflori, Os Draconis, Concha Margaritifera, Pericarpium Citri Reticulatae are decocted with water, add water 4 times amount for the first time, soak 60 minutes, intense fire decocts boiling, use slow fire boiling again 30 minutes, obtain first time decoction liquor;
(2) add water medicinal residues after first time filtration 2 times amount, decocts boiling, then within 20 minutes, namely obtain second time decoction liquor with slow fire boiling;
(3) by twice decoction liquor mixing, 3 doses are divided into take.
2. medicine according to claim 1, wherein the consumption of each crude drug is:
The Rhizoma Pinelliae 10 grams of Pericarpium Citri Reticulataes 15 grams of Caulis Bambusae In Taenia 8 grams
12 grams, Poria 10 grams of Fructus Aurantii Immaturuss 15 grams of Radix Glycyrrhizaes
Rhizoma Zingiberis Recens 8 grams of Fructus Jujubaes 20 grams of Radix Ophiopogonis 12 grams
Radix Adenophorae 15 grams of Flos Loniceraes 10 grams of Radix Rehmanniae 10 grams
The Rhizoma Atractylodis Macrocephalae 15 grams of Radix Codonopsis 10 gram liter fiber crops 15 grams
Radix Bupleuri 12 grams of Ramulus Uncariae Cum Uncis 15 grams of Radix Salviae Miltiorrhizaes 10 grams
Spica Prunellae 12 grams of Cortex Albiziaes 15 grams of Caulis Polygoni Multiflori 10 grams
Os Draconis 10 grams of Concha Margaritiferas 20 grams of Pericarpium Citri Reticulataes 15 grams.
3. the preparation method of medicine according to claim 1 or 2, is characterized in that: it comprises the following steps:
(1) get the raw materials ready
(1) Rhizoma Pinelliae: pick decontamination, sieve dedust bits;
(2) Pericarpium Citri Reticulatae: get crude drug, the peel of removing impurity and blackening, wash quickly is clean, softens, shredding, dries or cold drying, sieve dedust bits;
(3) Caulis Bambusae In Taenia: remove hard bamboo let, impurity, shakes off ash bits, is kneaded into little group or cutting;
(4) Poria: be soaked in water, cleans and pulls out, and after vexed, section, dries;
(5) Fructus Aurantii Immaturus: pick clean impurity, be soaked in water to eighty per cant thoroughly, pull out, profit, to interior without hard-core, cut into slices, is dried;
(6) Radix Glycyrrhizae: pick decontamination, cleans, and when being soaked in water saturating to eighty per cant, pulling out, runs through section, dry;
(7) Rhizoma Zingiberis Recens: pick decontamination, cleans earth, and the used time cuts into slices;
(8) Fructus Jujubae: pick clean impurity, dry;
(9) Radix Ophiopogonis: pick clean impurity, be soaked in water, pull out, pump the heart after running through, then clean dry;
(10) Radix Adenophorae: removing fibrous root, cleans, scrapes off rough bark, dry;
(11) Flos Lonicerae: sieve removes silt, picks clean impurity;
(12) Radix Rehmanniae: get crude drug, removing impurity, cleans, slightly moistens, cut sheet, dry, and sieve removes chip;
(13) Rhizoma Atractylodis Macrocephalae: pick clean impurity, be soaked in water, pull out after bubble, run through, section, dries;
(14) Radix Codonopsis: run through reed after cleaning silt, section or cutting, dry;
(15) Rhizoma Cimicifugae: pick decontamination, slightly foam washing is clean, pulls out, runs through, and section, dries;
(16) Radix Bupleuri: pick decontamination, removes residual stem, cleans silt, pulls out, run through rear timely section, dry immediately;
(17) Ramulus Uncariae Cum Uncis: pick old stalk, impurity, cleans, dries;
(18) Radix Salviae Miltiorrhizae: pick clean impurity, removing rhizome, cleans, pulls out, run through rear section, dry;
(19) Spica Prunellae: get crude drug, except discarding stalk, blade and impurity, sieve dedust bits;
(20) Cortex Albiziae: clear water soaks to be cleaned, and pulls out, is first divided into equal greatly rectangular after moistening, then stripping and slicing or shredding, dry;
(21) Caulis Polygoni Multiflori: clear water is cleaned, and slightly soak, pull out, after running through, cutting, dries;
(22) Os Draconis: outwash earth, smash;
(23) Concha Margaritifera: pick decontamination, knock fragment, sieve dedust bits;
(24) Pericarpium Citri Reticulatae: get crude drug, the peel of removing impurity and blackening, wash quickly is clean, softens, shredding, dries or cold drying, sieve dedust bits;
(2) prepare
(1) Rhizoma Pinelliae of described weight, Pericarpium Citri Reticulatae, Caulis Bambusae In Taenia, Poria, Fructus Aurantii Immaturus, Radix Glycyrrhizae, Rhizoma Zingiberis Recens, Fructus Jujubae, Radix Ophiopogonis, Radix Adenophorae, Flos Lonicerae, Radix Rehmanniae, the Rhizoma Atractylodis Macrocephalae, Radix Codonopsis, Rhizoma Cimicifugae, Radix Bupleuri, Ramulus Uncariae Cum Uncis, Radix Salviae Miltiorrhizae, Spica Prunellae, Cortex Albiziae, Caulis Polygoni Multiflori, Os Draconis, Concha Margaritifera, Pericarpium Citri Reticulatae are decocted with water, add water 4 times amount for the first time, soak 60 minutes, intense fire decocts boiling, use slow fire boiling again 30 minutes, obtain first time decoction liquor;
(2) add water medicinal residues after first time filtration 2 times amount, decocts boiling, then within 20 minutes, namely obtain second time decoction liquor with slow fire boiling;
(3) by twice decoction liquor mixing, 3 doses are divided into take.
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| CN104435891A (en) * | 2014-12-08 | 2015-03-25 | 杨其义 | Traditional Chinese medicine composition for treating intractable insomnia |
| CN105343795A (en) * | 2015-12-13 | 2016-02-24 | 张朝兰 | Drug for treating insomnia and preparation method thereof |
| CN111529636A (en) * | 2020-06-12 | 2020-08-14 | 川北医学院附属医院 | Traditional Chinese medicine composition for treating chronic insomnia, traditional Chinese medicine preparation and preparation method thereof |
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| 史俊芳.名医治疗失眠验案浅析.《山西中医学院学报》.2006,第7卷(第06期),8-9. * |
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