CN105343757A - Medicine for treating abdominal distention and preparation method of medicine - Google Patents
Medicine for treating abdominal distention and preparation method of medicine Download PDFInfo
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- CN105343757A CN105343757A CN201510950996.7A CN201510950996A CN105343757A CN 105343757 A CN105343757 A CN 105343757A CN 201510950996 A CN201510950996 A CN 201510950996A CN 105343757 A CN105343757 A CN 105343757A
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Abstract
The invention discloses a medicine for treating abdominal distention and a preparation method of the medicine. The medicine is mainly prepared from pinellia tuber, swordlike atractylodes rhizomes, officinal magnolia bark, tangerine peel, poria cocos, musk, villous amomum fruits, chicken's gizzard-membrane, liquorice, pilose asiabell roots, finger citron, virgate wormwood herb and the like by weight. The medicine has the functions of dampness elimination, depression removal, foulness repelling, qi depressing, heart calming and nerve soothing, takes effect quickly when used for treating abdominal distention, has a good curative effect and does not have side effects.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of abdominal distention and preparation method thereof, belong to the field of Chinese medicines.
Background technology
Abdominal distention is that a kind of abdominal part swells, the disease of color of the leather Rhizoma Curcumae Longae or distension and fullness of the chest and abdomen discomfort, and seemingly feeling of pressing is soft, and with QI rising in reverse order, belch, the symptoms such as tympanites.Many due to the pent-up of feelings will, gas imbalance reaches, and the injured or eating and drinking without temperance of liver spleen, be addicted to drink excessively, taste are injured, transformation failure of spleen, hinder caused by QI-blood circulation.Because Western medicine cannot effective fast treating abdominal distention, therefore there is great demand in the Chinese medicine of people to effective treatment abdominal distention, up to now, also do not find about relevant report of the present invention.
Summary of the invention
The present inventor, according to the research of theory of Chinese medical science and the checking repeatedly of clinical trial, finally have found the medicine of effectively treatment abdominal distention, thus completes the present invention.
Object of the present invention is just to provide a kind of Chinese medicine composition of more effective treatment abdominal distention.
Another object of the present invention just there is provided the preparation method of this Chinese medicine composition.
Medicine of the present invention selects the Rhizoma Pinelliae, Rhizoma Atractylodis, Cortex Magnoliae Officinalis, Pericarpium Citri Reticulatae, Poria, Herba Pogostemonis, Fructus Amomi, Endothelium Corneum Gigeriae Galli, Radix Glycyrrhizae, Radix Codonopsis, Fructus Citri Sarcodactylis, Herba Artemisiae Scopariae, Semen Persicae, Fructus Gardeniae, Fructus Forsythiae, Cortex Albiziae, Semen Coicis, Semen Phaseoli, Radix Bupleuri, the Radix Paeoniae Alba, Rhizoma Cyperi, Fructus Aurantii, Caulis Bambusae In Taenia, Radix Platycodonis, Radix Angelicae Sinensis, Cortex Moutan, Flos Carthami, the Radix Rehmanniae, Semen Alpiniae Katsumadai, Cortex Magnoliae Officinalis, Rhizoma Dioscoreae to carry out combination preparation, made by these drug regimens each efficacy of drugs produce synergism, thus effectively can treat abdominal distention.Wherein, select the Rhizoma Pinelliae to be because its nature and flavor are pungent, temperature, poisonous, enter spleen, stomach warp, have drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, the function of dissolving lump and resolving mass, control the vomiting of damp-phlegm cold drink, regurgitation, cough with asthma abundant expectoration, my diaphragm distension, syncope due to accumulation of phlegm is had a headache, dizzy sleeplessness, outer subduing inflammation.Rhizoma Atractylodis are selected to be that temperature, enters spleen, stomach warp, have spleen invigorating, dampness, resolving depression, ward off dirty function because its nature and flavor are worked hard, control wet Sheng and be stranded spleen, asthenia drowsiness, gastral cavity painful abdominal mass abdominal distention, inappetence, vomiting, has loose bowels, dysentery, malaria, phlegm retention, edema, seasonal epidemic pathogens is caught a cold, anemofrigid-damp arthralgia, flaccidity of the lower limbs, nyctalopia.Select Cortex Magnoliae Officinalis to be because its nature and flavor toil, temperature, enter spleen, stomach, large intestine channel, have warming middle-JIAO, the therapeutic method to keep the adverse QI flowing downwards, dampness, the function of expectorant, control breast abdomen feeling of fullness distending pain, regurgitation, vomiting, dyspepsia does not disappear, and phlegm retention is breathed with cough, cold-damp dysentery.Pericarpium Citri Reticulatae is selected to be that temperature, return lung, spleen channel, have regulating qi-flowing for strengthening spleen, the function of drying dampness to eliminate phlegm, controls fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm because its nature and flavor are bitter, pungent.Select Poria to be because its property slightly sweet flavor, flat, enter the heart, spleen, lung meridian, have eliminating dampness and diuresis, strengthening the spleen stomach function regulating, the function of mind tranquilizing and the heart calming, control dysuria edema distending pain, phlegm retention cough with dyspnea, the sound of vomiting of vomitting, has loose bowels, seminal emission, stranguria with turbid discharge, and palpitation with fear is forgetful.Herba Pogostemonis is selected to be that tepor, enters lung, spleen, stomach warp, have fast gas because its nature and flavor are pungent, and in, ward off dirty, the function of damp eliminating, cure cold heat-damp in summer, cold and heat, and headache, breast gastral cavity painful abdominal mass is vexed, and vomiting is had loose bowels, malaria, dysentery, halitosis.Select Fructus Amomi to be that temperature, enters spleen, stomach warp because its nature and flavor are pungent, in having circulation of qi promoting to adjust, stomach function regulating, the function of being amusing, control stomachache painful abdominal mass swollen, anorexia dyspepsia, chokes every vomiting, diarrhea due to cold pathogen cold-dysentery, pregnant fetal movement.Select Endothelium Corneum Gigeriae Galli to be because its nature and flavor are sweet, flat, enter spleen, stomach warp, control stagnant, the function of strengthening the spleen and stomach, control food stagnation distension, vomiting regurgitation, dysentery, infantile malnutrition, quenches one's thirst, incontinence of urine, sore throat tonsillitis, ulcerative gingivitis aphtha.Select Radix Glycyrrhizae to be because its nature and flavor are sweet flat, enter spleen, stomach, lung meridian, have and middle emergency, lung moistening, removing toxic substances, the function of coordinating the actions of various ingredients in a prescription, process with controlling weakness of the spleen and stomach, lack of appetite, stomachache loose stool, overstrain generates heat, and consumptive lung disease is coughed, cardiopalmus, frightened carbuncle, raw with controlling laryngopharynx swelling and pain, peptic ulcer, ulcer sores, separates poison of drug and alimentary toxicosis.Select Radix Codonopsis to be because its nature and flavor are sweet, flat, start with, meridian of Foot-TAI YIN edema caused by disorder of QI, have invigorating the spleen and replenishing QI, the function of promoting the production of body fluid, controls weakness of the spleen and stomach, deficiency of both QI and blood, fatigue and lack of strength, and lack of appetite is thirsty, chronic diarrhea, proctoptosis.Selecting Fructus Citri Sarcodactylis, different name Fructus Citri Sarcodactylis, Bergamot, is that temperature, enter liver, stomach warp, regulate the flow of vital energy, the function of reducing phlegm, treats for stomachache, and coerces swollen, vomiting, dysphagic, phlegm retention cough with asthma, and can relieve the effect of alcohol because the arduous acid of its nature and flavor.Herba Artemisiae Scopariae is selected to be because its nature and flavor toil, cool, enter liver, spleen, urinary bladder channel, have the function of clearing away heat-damp and promoting diuresis, control jaundice due to damp-heat, dysuria, pruritus due to wind pathogen skin ulcer scabies.Semen Persicae is selected to be because its property bitter but sweet flavor, flat, enter the heart, liver, large intestine channel, have blood stasis removing and clots absorbing, moisturize the function of sliding warp, control amenorrhea, mass in the abdomen, calentura blood-retention, arthralgia due to stagnation of blood, malaria, traumatic injury, swelling and pain due to blood stasis, the dry constipation of blood.Select Fructus Gardeniae to be because its nature and flavor are bitter, cold, enter the heart, liver, lung, stomach warp, have heat clearing away, pathogenic fire purging, the function of removing heat from blood, control calentura restlessness of asrhenia type and insomnia, jaundice, gonorrhea, quench one's thirst, conjunctival congestion, pharyngalgia, spit blood, epistaxis, dysentery, hematuria, pathopyretic ulcer, sprains and swells and ache.Select Fructus Forsythiae to be because its nature and flavor are bitter, cool, enter the heart, liver, gallbladder meridian, have heat clearing away, removing toxic substances, eliminating stagnation, the function of detumescence, controls warm, erysipelas, macule, carbuncle and ulcer toxic swelling, scrofula, urine stranguria with urinary obstruction.Cortex Albiziae is selected to be because its nature and flavor are sweet, flat, enter the heart, Liver Channel, have resolving depression, and blood, mind calming, the function of subduing inflammation, controls irritability, melancholy insomnia, lung abscess, carbuncle, scrofula, injured bone.Semen Coicis is selected to be that cool, enter spleen, lung, kidney channel, have spleen invigorating, tonifying the lung, heat clearing away, the function of dampness removing, controls and have loose bowels, arthralgia chiefly caused by damp pathogen, the contracture of muscle arteries and veins, joint stuffiness, edema, beriberi, consumptive lung disease, lung abscess, acute appendicitis, stranguria with turbid discharge, leucorrhea because its property slightly sweet flavor.Semen Phaseoli is selected to be because the sweet acid of its nature and flavor, flat, enter the heart, small intestine meridian, have diuretic to dehumidify, and blood evacuation of pus, the function of subduing swelling and detoxicating, harnesses the river swollen, beriberi, jaundice, and dysentery, has blood in stool, carbuncle.Select Radix Bupleuri to be that cool, enter liver, gallbladder meridian, have reconciling superficies and interior, soothing the liver, the function of yang invigorating, controls alternate attack of chill and fever, fullness in the chest and hypochondriac pain because its nature and flavor are bitter, bitter taste is deaf, headache and dizziness, malaria, lower sharp proctoptosis, menoxenia, uterine prolapse.Select the Radix Paeoniae Alba to be because its nature and flavor picric acid, cool, enter liver, spleen channel, have nourishing blood to suppress the hyperactive liver, pain relieving in slow, yin fluid astringing receives the function of antiperspirant, controls the breast abdomen pain over the hypochondriac region, and dysentery is suffered from abdominal pain, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia.Rhizoma Cyperi is selected to be because the pungent micro-hard work of its nature and flavor, flat, enter liver, tri-jiao channel, resolving depression of regulating the flow of vital energy, the function of pain relieving regulating menstruation, treating the liver discomfort in the stomach, depression of QI, breast abdomen distending pain over the hypochondrium, phlegm retention feeling of fullness, menoxenia, bleeding not during menses.Fructus Aurantii is selected to be because its nature and flavor toil, cool.Enter lung, spleen, large intestine channel.Dispelling the stagnated QI, row expectorant, removing food stagnancy.Control chest and diaphragm expectorant stagnant, the feeling of stuffiness in chest, coerce swollen, food stagnation, eructation, vomiting, heavy after dysentery, proctoptosis, uterine prolapse.Select Caulis Bambusae In Taenia to be because its nature and flavor are sweet, cool, enter stomach, gallbladder meridian, have heat clearing away, removing heat from blood, reduce phlegm, the function of emesis, control dysphoria with smothery sensation vomiting, singultus, expectorant heat syndrome cough is breathed heavily, and spits blood, epistaxis, metrorrhagia, malignant histocytosis, fetal movement , Jing Epilepsy.Select Radix Platycodonis to be because its nature and flavor toil, flat, enter lung, stomach warp, have out lung qi dispersing gas, the function of evacuation of pus of eliminating the phlegm, controls exogenous cough, laryngopharynx swelling and pain, lung abscess vomiting pus, fullness in the chest and hypochondriac pain, and dysentery is suffered from abdominal pain.Select Radix Angelicae Sinensis to be because its nature and flavor sweet, acrid, warm, enter the heart, liver, spleen channel, have benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturize the function of laxation, control menoxenia, amenorrhea stomachache , mass in the abdomen knot is poly-, metrorrhagia, and headache due to deficiency of blood is dizzy, flaccidity syndrome and arthralgia syndrome, dryness of the intestine difficulty is just, heavy after bloody dysentery, ulcer sores, incised wound, injury from falling down.Cortex Moutan is selected to be because its nature and flavor are worked hard, cool, enter the heart, liver, kidney channel, have heat clearing away, removing heat from blood, and blood, the function of repercussive, controls the pathogenic heat attacking blood system in febrile diseases, and send out speckle , Jing Epilepsy, tell, be defeated in battle, have blood in stool, hectic fever due to YIN-deficiency consumptive fever, amenorrhea , mass in the abdomen, carbuncle and ulcer, flutters damage.Select Flos Carthami to be that temperature, enters the heart, Liver Channel, have promoting blood circulation to restore menstrual flow, the function of blood stasis removing pain relieving, control amenorrhea , mass in the abdomen because its nature and flavor are pungent, difficult labour, stillborn fetus, disease that postpartum lochia can't go, blood stasis is had a pain, carbuncle, injury from falling down.Select Radix Rehmanniae to be that cold, GUIXIN, liver, kidney channel, have clearing away heat and cooling blood, yin nourishing, the function of promoting the production of body fluid, and controls calentura excessive thirst, yin asthenia generating intrinsic heat, hectic fever due to YIN-deficiency consumptive fever, and interior-heat is quenched one's thirst because its nature and flavor are sweet, spit blood, epistaxis, sends out speckle dermexanthesis.Select Semen Alpiniae Katsumadai to be that temperature, enters spleen, stomach warp, have warming middle-JIAO, cold relieving, circulation of qi promoting, the function of dampness, control trusted subordinate's cold type of pain, feeling of fullness dyspepsia, dysphagia and regurgitation because its nature and flavor are pungent, cold-damp is vomited and diarrhoea, and phlegm retention is gathered.Select Cortex Magnoliae Officinalis to be because its nature and flavor toil, temperature, enter spleen, stomach, large intestine channel, have warming middle-JIAO, the therapeutic method to keep the adverse QI flowing downwards, dampness, the function of expectorant, control breast abdomen feeling of fullness distending pain, regurgitation, vomiting, dyspepsia does not disappear, and phlegm retention is breathed with cough, cold-damp dysentery.Select Rhizoma Dioscoreae to be because its nature and flavor are sweet, flat, enter lung, spleen, kidney channel, have spleen invigorating, tonifying the lung, reinforce the kidney, the function of benefit essence, controls diarrhea due to hypofunction of the spleen, chronic dysentery, cough due to consumptive disease, quenches one's thirst, seminal emission, leukorrhagia, frequent micturition.
Detailed description of the invention
The drug dose of instant component is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good curative effect within the scope of following weight:
Rhizoma Pinelliae 10-15 gram, Rhizoma Atractylodis 10-15 gram, Cortex Magnoliae Officinalis 10-15 gram, Pericarpium Citri Reticulatae 10-15 gram, Poria 10-15 gram, Herba Pogostemonis 10-15 gram, Fructus Amomi 6-9 gram, Endothelium Corneum Gigeriae Galli 10-15 gram, Radix Glycyrrhizae 4-8 gram, Radix Codonopsis 10-15 gram, Fructus Citri Sarcodactylis 10-15 gram, Herba Artemisiae Scopariae 5-15 gram, Semen Persicae 10-15 gram, Fructus Gardeniae 10-15 gram, Fructus Forsythiae 5-15 gram, Cortex Albiziae 10-15 gram, Semen Coicis 10-15 gram, Semen Phaseoli 20-30 gram, Radix Bupleuri 5-10 gram, Radix Paeoniae Alba 5-10 gram, Rhizoma Cyperi 8-10 gram, Fructus Aurantii 8-12 gram, Caulis Bambusae In Taenia 10-15 gram, Radix Platycodonis 5-15 gram, Radix Angelicae Sinensis 10-15 gram, Cortex Moutan 5-15 gram, Flos Carthami 4-8 gram, Radix Rehmanniae 10-15 gram, 4-6 gram, Semen Alpiniae Katsumadai 6-8 gram, Cortex Magnoliae Officinalis 5-15 gram, Rhizoma Dioscoreae 10-15 gram
Be preferably:
The Rhizoma Pinelliae 12 grams, Rhizoma Atractylodis 12 grams, Cortex Magnoliae Officinalis 12 grams, Pericarpium Citri Reticulatae 12 grams, 12 grams, Poria, Herba Pogostemonis 12 grams, Fructus Amomi 9 grams, Endothelium Corneum Gigeriae Galli 12 grams, 6 grams, Radix Glycyrrhizae, Radix Codonopsis 12 grams, Fructus Citri Sarcodactylis 15 grams, Herba Artemisiae Scopariae 10 grams, 12 grams, Semen Persicae, Fructus Gardeniae 15 grams, Fructus Forsythiae 10 grams, Cortex Albiziae 15 grams, Semen Coicis 12 grams, Semen Phaseoli 25 grams, Radix Bupleuri 9 grams, the Radix Paeoniae Alba 10 grams, Rhizoma Cyperi 10 grams, Fructus Aurantii 9 grams, Caulis Bambusae In Taenia 12 grams, Radix Platycodonis 9 grams, Radix Angelicae Sinensis 10 grams, Cortex Moutan 10 grams, 6 grams, Flos Carthami, Radix Rehmanniae 15 grams, 6 grams, Semen Alpiniae Katsumadai 8 grams, Cortex Magnoliae Officinalis 8 grams, Rhizoma Dioscoreae 8 grams
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, the Rhizoma Pinelliae: pick decontamination, sieve dedust bits;
2, Rhizoma Atractylodis: pick decontamination, with blister to seven, most probably thoroughly, pull out, run through rear section, dry;
3, Cortex Magnoliae Officinalis: be soaked in water and pull out, scrapes off rough bark after running through, and clean, shredding, dries;
4, Pericarpium Citri Reticulatae: get crude drug, the peel of removing impurity and blackening, wash quickly is clean, softens, shredding, dries or cold drying, sieve dedust bits;
5, Poria: be soaked in water, cleans and pulls out, and after vexed, section, dries;
6, Herba Pogostemonis: pick decontamination, removing undesirable root and old stem, first taken by leaf and separately put, stem water runs through, and cutting is dried, then with leaf and even;
7, Fructus Amomi: pick decontamination and shell, smash to pieces;
8, Endothelium Corneum Gigeriae Galli: pick decontamination, rinses and dries;
9, Radix Glycyrrhizae: pick decontamination, cleans, and when being soaked in water saturating to eighty per cant, pulling out, run through, section, dries;
10, Radix Codonopsis: run through reed after cleaning silt, section or cutting, dry;
11, Fructus Citri Sarcodactylis: pick decontamination, after water spray profit, chopping, dries;
12, Herba Artemisiae Scopariae: sieve, picks decontamination, and removing undesirable root, pulverizes, remove spare after sieve;
13, Semen Persicae: removing duricrust impurity, puts in boiling water pot and boils to the micro-wrinkle of crust, pull out, immerse in cold water, rub with the hands and remove seed coat, dry, winnow with a dustpan clean;
14, Fructus Gardeniae: sieve dedust bits, pick decontamination, pulverize and sieve;
15, Fructus Forsythiae: pick clean impurity, stranding is opened, except discarding stalk;
16, Cortex Albiziae: clear water soaks to be cleaned, and pulls out, is first divided into equal greatly rectangular after moistening, then stripping and slicing or shredding, dry;
17, Semen Coicis: get crude drug, removing residual cot, impurity;
18, Semen Phaseoli: get crude drug, removing impurity, the used time smashs to pieces;
19, Radix Bupleuri: pick decontamination, removes residual stem, cleans silt, pulls out, run through rear timely section, dry immediately;
20, the Radix Paeoniae Alba: pick decontamination, separately size, be soaked in water to eighty per cant thoroughly, pull out, solarization is dried in the air, and profit is even to inside and outside humidity, and section is dry;
21, Rhizoma Cyperi: pick decontamination, is ground into particle, winnow with a dustpan fine, soft fur and smalls;
22, Fructus Aurantii: get wheat bran and be spread in hot pot, when yellow skin of waiting is smoldered, adds Fructus Aurantii sheet, and fry to faint yellow, take out, sieve removes wheat bran, cools, every Fructus Aurantii sheet 100 jin, with 10 jin, wheat bran;
23, Caulis Bambusae In Taenia: remove hard bamboo let, impurity, shakes off ash bits, is kneaded into little group or cutting
24, Radix Platycodonis: pick clean impurity, except removing LU, cleans and pulls out, run through rear section, dry;
25, Radix Angelicae Sinensis: pick decontamination, clean, moistening, slightly dries in the air, and section is dried;
26, Cortex Moutan: pick decontamination, removing core, cleans, runs through, and section, dries;
27, Flos Carthami: pick clean impurity, removing stem and leaf, base of a fruit head, dry;
28, Radix Rehmanniae: get crude drug, removing impurity, cleans, slightly moistens, cut sheet, dry, and sieve removes chip;
29, Semen Alpiniae Katsumadai: pick clean impurity, shell and get core, the used time smashs to pieces;
30, Cortex Magnoliae Officinalis: be soaked in water and pull out, scrapes off rough bark after running through, and clean, shredding, dries;
31, Rhizoma Dioscoreae: pick clean impurity, is soaked in water to Rhizoma Dioscoreae central part is softening, pulls out and slightly dry in the air, and section is dried or dried;
Two, prepare
1, the Rhizoma Pinelliae of described weight, Rhizoma Atractylodis, Cortex Magnoliae Officinalis, Pericarpium Citri Reticulatae, Poria, Herba Pogostemonis, Fructus Amomi, Endothelium Corneum Gigeriae Galli, Radix Glycyrrhizae, Radix Codonopsis, Fructus Citri Sarcodactylis, Herba Artemisiae Scopariae, Semen Persicae, Fructus Gardeniae, Fructus Forsythiae, Cortex Albiziae, Semen Coicis, Semen Phaseoli, Radix Bupleuri, the Radix Paeoniae Alba, Rhizoma Cyperi, Fructus Aurantii, Caulis Bambusae In Taenia, Radix Platycodonis, Radix Angelicae Sinensis, Cortex Moutan, Flos Carthami, the Radix Rehmanniae, Semen Alpiniae Katsumadai, Cortex Magnoliae Officinalis, Rhizoma Dioscoreae are added in decocting container, add water 8 times amount for the first time, soak after 150 minutes, intense fire decocts boiling, use slow fire boiling again 30 minutes, filter first time decoction liquor, first time decoction liquor is poured in container.
2, add water the medicinal residues of filtration 6 times amount, first boils with high heat, then within 20 minutes, filter with slow fire boiling, second time decoction liquor poured in container.
3, by twice decoction liquor mixing and stirring, be divided into 4 doses and take.
In prescription, the Rhizoma Pinelliae has drying dampness to eliminate phlegm, and the function of dissolving lump and resolving mass is monarch drug; Rhizoma Atractylodis spleen invigorating, dampness, resolving depression, wards off dirty, Cortex Magnoliae Officinalis warming middle-JIAO, the therapeutic method to keep the adverse QI flowing downwards, dampness, and the two is ministerial drug, and three taste medicines play dampness resolving depression jointly, the effect of dissolving lump and resolving mass, and treatment abdominal distention effect is comprehensive; And with drying dampness to eliminate phlegm dissolving lump and resolving mass for master can be effected a permanent cure.Herba Pogostemonis has fast gas, and in, warding off dirty, the function of damp eliminating, is adjuvant drug; Radix Glycyrrhizae has and middle emergency, lung moistening, and removing toxic substances, the function of coordinating the actions of various ingredients in a prescription, all medicines take stopgap measures with being left.
Medicine of the present invention has dampness resolving depression, wards off the dirty therapeutic method to keep the adverse QI flowing downwards, and the function of dissolving lump and resolving mass, is used for the treatment of abdominal distention, short treating period, instant effect, non-relapse after healing, has no side effect.
Detailed description of the invention:
Set forth the beneficial effect of medicine of the present invention further below by way of test example, these test examples comprise animal toxicity test report and the clinical observation on the therapeutic effect data of medicine of the present invention.
The animal toxicity test report of [test example 1] medicine of the present invention:
Get rabbit 30, male and female dual-purpose, body weight 2.0-2.5kg, divide two groups, often organize 15, wherein one group is overdose test group, and another group is normal amount test group.Taking medicinal liquid super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is administration by gavage administration, twice daily, serve on 7 days, observes administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.
The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention
1, physical data
Accept abdominal distention out-patient totally 32 examples for medical treatment.
2, diagnostic criteria
Clinically, abdominal distention shows as uncomfortable in chest more, xerostomia, and the colour of skin is sallow, and sticky in mouth, the white or jaundice of the greasy color of thick fur, and limbs are tired heavy, and muscle is fertile and not hard etc.
3, Therapeutic Method
Select above-mentioned medicament, take to patient, each serving with 1 dose, every day early, evening respectively takes 1 time, within 7 days, is a course for the treatment of, takes 3 courses for the treatment of continuously.
4, efficacy assessment standard
Effective: abdominal distention transference cure, recovery from illness, body constitution recovers normal;
Take a turn for the better: abdominal distention symptom is clearly better, and body constitution is progressively recovered;
Invalid: not reach improvement standard person.
5, therapeutic outcome (seeing the following form)
In above-mentioned treatment, by Drug therapy abdominal distention patient 32 example of the present invention, effective 28 examples of result, obvious effective rate is 87.50%, and take a turn for the better 3 examples, and improvement rate is 9.37%, and invalid 1 example, total effective rate is 96.87%.
Claims (3)
1. treat a medicine for abdominal distention, it is characterized in that: it is made up of the crude drug in following amount ranges:
Rhizoma Pinelliae 10-15 gram, Rhizoma Atractylodis 10-15 gram, Cortex Magnoliae Officinalis 10-15 gram, Pericarpium Citri Reticulatae 10-15 gram, Poria 10-15 gram, Herba Pogostemonis 10-15 gram, Fructus Amomi 6-9 gram, Endothelium Corneum Gigeriae Galli 10-15 gram, Radix Glycyrrhizae 4-8 gram, Radix Codonopsis 10-15 gram, Fructus Citri Sarcodactylis 10-15 gram, Herba Artemisiae Scopariae 5-15 gram, Semen Persicae 10-15 gram, Fructus Gardeniae 10-15 gram, Fructus Forsythiae 5-15 gram, Cortex Albiziae 10-15 gram, Semen Coicis 10-15 gram, Semen Phaseoli 20-30 gram, Radix Bupleuri 5-10 gram, Radix Paeoniae Alba 5-10 gram, Rhizoma Cyperi 8-10 gram, Fructus Aurantii 8-12 gram, Caulis Bambusae In Taenia 10-15 gram, Radix Platycodonis 5-15 gram, Radix Angelicae Sinensis 10-15 gram, Cortex Moutan 5-15 gram, Flos Carthami 4-8 gram, Radix Rehmanniae 10-15 gram, 4-6 gram, Semen Alpiniae Katsumadai 6-8 gram, Cortex Magnoliae Officinalis 5-15 gram, Rhizoma Dioscoreae 10-15 gram.
2. medicine according to claim 1, wherein the consumption of each crude drug is:
The Rhizoma Pinelliae 12 grams, Rhizoma Atractylodis 12 grams, Cortex Magnoliae Officinalis 12 grams, Pericarpium Citri Reticulatae 12 grams, 12 grams, Poria, Herba Pogostemonis 12 grams, Fructus Amomi 9 grams, Endothelium Corneum Gigeriae Galli 12 grams, 6 grams, Radix Glycyrrhizae, Radix Codonopsis 12 grams, Fructus Citri Sarcodactylis 15 grams, Herba Artemisiae Scopariae 10 grams, 12 grams, Semen Persicae, Fructus Gardeniae 15 grams, Fructus Forsythiae 10 grams, Cortex Albiziae 15 grams, Semen Coicis 12 grams, Semen Phaseoli 25 grams, Radix Bupleuri 9 grams, the Radix Paeoniae Alba 10 grams, Rhizoma Cyperi 10 grams, Fructus Aurantii 9 grams, Caulis Bambusae In Taenia 12 grams, Radix Platycodonis 9 grams, Radix Angelicae Sinensis 10 grams, Cortex Moutan 10 grams, 6 grams, Flos Carthami, Radix Rehmanniae 15 grams, 6 grams, Semen Alpiniae Katsumadai 8 grams, Cortex Magnoliae Officinalis 8 grams, Rhizoma Dioscoreae 8 grams.
3. the preparation method of medicine according to claim 1 or 2, it comprises the following steps:
(1) get the raw materials ready
(1) Rhizoma Pinelliae: pick decontamination, sieve dedust bits;
(2) Rhizoma Atractylodis: pick decontamination, with blister to seven, most probably thoroughly, pull out, run through rear section, dry;
(3) Cortex Magnoliae Officinalis: be soaked in water and pull out, scrapes off rough bark after running through, and clean, shredding, dries;
(4) Pericarpium Citri Reticulatae: get crude drug, the peel of removing impurity and blackening, wash quickly is clean, softens, shredding, dries or cold drying, sieve dedust bits;
(5) Poria: be soaked in water, cleans and pulls out, and after vexed, section, dries;
(6) Herba Pogostemonis: pick decontamination, removing undesirable root and old stem, first taken by leaf and separately put, stem water runs through, and cutting is dried, then with leaf and even;
(7) Fructus Amomi: pick decontamination and shell, smash to pieces;
(8) Endothelium Corneum Gigeriae Galli: pick decontamination, rinses and dries;
(9) Radix Glycyrrhizae: pick decontamination, cleans, and when being soaked in water saturating to eighty per cant, pulling out, run through, section, dries;
(10) Radix Codonopsis: run through reed after cleaning silt, section or cutting, dry;
(11) Fructus Citri Sarcodactylis: pick decontamination, after water spray profit, chopping, dries;
(12) Herba Artemisiae Scopariae: sieve, picks decontamination, and removing undesirable root, pulverizes, remove spare after sieve;
(13) Semen Persicae: removing duricrust impurity, puts in boiling water pot and boils to the micro-wrinkle of crust, pull out, immerse in cold water, rub with the hands and remove seed coat, dry, winnow with a dustpan clean;
(14) Fructus Gardeniae: sieve dedust bits, pick decontamination, pulverize and sieve;
(15) Fructus Forsythiae: pick clean impurity, stranding is opened, except discarding stalk;
(16) Cortex Albiziae: clear water soaks to be cleaned, and pulls out, is first divided into equal greatly rectangular after moistening, then stripping and slicing or shredding, dry;
(17) Semen Coicis: get crude drug, removing residual cot, impurity;
(18) Semen Phaseoli: get crude drug, removing impurity, the used time smashs to pieces;
(19) Radix Bupleuri: pick decontamination, removes residual stem, cleans silt, pulls out, run through rear timely section, dry immediately;
(20) Radix Paeoniae Alba: pick decontamination, separately size, be soaked in water to eighty per cant thoroughly, pull out, solarization is dried in the air, and profit is even to inside and outside humidity, and section is dry;
(21) Rhizoma Cyperi: pick decontamination, is ground into particle, winnow with a dustpan fine, soft fur and smalls;
(22) Fructus Aurantii: get wheat bran and be spread in hot pot, when yellow skin of waiting is smoldered, adds Fructus Aurantii sheet, and fry to faint yellow, take out, sieve removes wheat bran, cools, every Fructus Aurantii sheet 100 jin, with 10 jin, wheat bran;
(23) Caulis Bambusae In Taenia: remove hard bamboo let, impurity, shakes off ash bits, is kneaded into little group or cutting
(24) Radix Platycodonis: pick clean impurity, except removing LU, cleans and pulls out, run through rear section, dry;
(25) Radix Angelicae Sinensis: pick decontamination, clean, moistening, slightly dries in the air, and section is dried;
(26) Cortex Moutan: pick decontamination, removing core, cleans, runs through, and section, dries;
(27) Flos Carthami: pick clean impurity, removing stem and leaf, base of a fruit head, dry;
(28) Radix Rehmanniae: get crude drug, removing impurity, cleans, slightly moistens, cut sheet, dry, and sieve removes chip;
(29) Semen Alpiniae Katsumadai: pick clean impurity, shell and get core, the used time smashs to pieces;
(30) Cortex Magnoliae Officinalis: be soaked in water and pull out, scrapes off rough bark after running through, and clean, shredding, dries;
(31) Rhizoma Dioscoreae: pick clean impurity, is soaked in water to Rhizoma Dioscoreae central part is softening, pulls out and slightly dry in the air, and section is dried or dried;
(2) prepare
(1) Rhizoma Pinelliae of described weight, Rhizoma Atractylodis, Cortex Magnoliae Officinalis, Pericarpium Citri Reticulatae, Poria, Herba Pogostemonis, Fructus Amomi, Endothelium Corneum Gigeriae Galli, Radix Glycyrrhizae, Radix Codonopsis, Fructus Citri Sarcodactylis, Herba Artemisiae Scopariae, Semen Persicae, Fructus Gardeniae, Fructus Forsythiae, Cortex Albiziae, Semen Coicis, Semen Phaseoli, Radix Bupleuri, the Radix Paeoniae Alba, Rhizoma Cyperi, Fructus Aurantii, Caulis Bambusae In Taenia, Radix Platycodonis, Radix Angelicae Sinensis, Cortex Moutan, Flos Carthami, the Radix Rehmanniae, Semen Alpiniae Katsumadai, Cortex Magnoliae Officinalis, Rhizoma Dioscoreae are added in decocting container, add water 8 times amount for the first time, soak after 150 minutes, intense fire decocts boiling, use slow fire boiling again 30 minutes, filter first time decoction liquor, first time decoction liquor is poured in container;
(2) add water the medicinal residues of filtration 6 times amount, first boils with high heat, then within 20 minutes, filter with slow fire boiling, pours in container by second time decoction liquor;
(3) by twice decoction liquor mixing and stirring, be divided into 4 doses and take.
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