CN102293975A - Medicine for treating phthisis and preparation method thereof - Google Patents

Abstract

The invention discloses a medicine for treating phthisis, and a preparation method thereof. The medicine is mainly prepared from donkeyhide glue, natural indigo, flaccid aster herb, common bletilla pseudobulb, root of Szechwan-Yunnan sanicle, platycodon grandiflorus, ladybell root, Japanese metaplexis pericarp, stauntonvine and dwarf lilyturf tuber in a certain weight ratio. The medicine for treating phthisis can be prepared into any common oral formulation. The medicine has the effects of clearing heat and cooling blood, promoting pus discharge and regenerating tissue and invigorating the circulation of blood and removing blood stasis, a good effect of treating phthisis and quick response; and phthisis does not relapse.

Description

Phthisical medicine of a kind of treatment and preparation method thereof

Technical field

The present invention relates to the phthisical medicine of a kind of treatment, belong to the field of Chinese medicines.

Background technology

Pulmonary tuberculosis is commonly called as pulmonary tuberculosis, being to invade the pulmonary infection that causes in the human body by tubercule bacillus, also is a kind of chronic and deferred infectious disease that youngster is suffered from easily, and 16-40 years old is the age occurred frequently lungy, all can fall ill throughout the year, be 4-8 weeks incubation period after infecting.During outbreak, pale complexion, health is become thin, and violent cough seriously influences life and sleep, and western medical treatment is many based on antiinflammatory, antiviral Western medicine symptomatic treatment at present, but doctor trained in Western medicine drug cost height, the course of treatment is long, and effect is undesirable.

Summary of the invention

Therefore people to curative effect preferably Chinese medicine have great demand, up to now, also do not find to the purpose of this invention is to provide the Chinese medicine composition medicine that a kind of curative effect is treated pulmonary tuberculosis preferably about relevant report of the present invention.

Another object of the present invention has just provided the preparation method of this composition of medicine.

The present invention selects Colla Corii Asini, the Radix Astragali, Indigo Naturalis, Radix Glycyrrhizae, Radix Rehmanniae, Herba Asteris Flaccidi, Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Asparagi, Folium Mori, Cortex Moutan, Rhizoma Imperatae, Radix Codonopsis, the Rhizoma Pinelliae, Radix Gentianae, Radix Saniculae Astrantifoliae, Radix Dipsaci, the Radix Stemonae, Radix Gentianae Macrophyllae, Lignum Aquilariae Resinatum, Radix Platycodonis, Radix Scrophulariae, Radix Stellariae, Depositum urinae preparatum, Pericarpium Metaplexis, Caulis Bambusae In Taenia, Cordyceps, Radix Rehmanniae Preparata, Concha Haliotidis, Bulbus Fritillariae Cirrhosae, Radix Adenophorae, Poria, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Radix Et Rhizoma Rhei, Fructus Schisandrae Chinensis, Caulis et folium stauntoniae, Radix Ophiopogonis 30 seven flavor medicines make up, these drug regimens are made each drug regimen, make each efficacy of drugs produce synergism, thereby can effectively treat phthisical recurrence, wherein select for use Colla Corii Asini to be because its nature and flavor are sweet flat, go into lung, liver, kidney channel, nourishing YIN and supplementing blood is arranged, antiabortive function, control blood deficiency, cough due to consumptive disease, spit blood, epistaxis, have blood in stool, menoxenia, metrorrhagia is controlled leakage.Select for use the Radix Astragali to be because its nature and flavor are sweet, tepor is gone into lung, spleen channel, give birth to the useful consolidating superficial resistance of defending, and inducing diuresis to remove edema, poison holding, the function of granulation promoting is controlled spontaneous perspiration, night sweat, arthralgia due to stagnation of blood, edema, carbuncle are not burst or are burst and hold back for a long time; Process with the function that the invigorating middle warmer benefit is arranged, control the internal injury overstrain, diarrhea due to hypofunction of the spleen, proctoptosis, deficiency of vital energy blood prostration, the disease of metrorrhagia and leukorrhagia and all weakness of QI blood deficiency.Select for use Indigo Naturalis to be because its nature and flavor are salty, cold, go into liver, lung, stomach warp, heat clearing away is arranged, removing heat from blood, the antidotal function is controlled the epidemic febrile disease intenseness of heat, and macule is spitted blood, is spat blood, Xiao Jing Epilepsy, skin ulcer is swollen, erysipelas, snake bite and insect sting.Select for use Radix Glycyrrhizae to be because its nature and flavor are sweet flat, go into spleen, stomach, lung meridian, have and middle emergency, lung moistening, detoxifcation, the function of coordinating the actions of various ingredients in a prescription, process with controlling weakness of the spleen and stomach, lack of appetite, stomachache loose stool, the overstrain heating, consumptive lung disease cough, cardiopalmus, frightened carbuncle is given birth to controlling laryngopharynx swelling and pain, peptic ulcer, ulcer sores is separated poison of drug and alimentary toxicosis.Select for use Radix Rehmanniae to be because its nature and flavor are sweet, cold, GUIXIN, liver, kidney channel have clearing away heat and cooling blood, yin nourishing, and the function of promoting the production of body fluid is controlled the calentura excessive thirst, interior-heat caused by deficiency of YIN, the hectic fever due to YIN-deficiency consumptive fever, interior-heat is quenched one's thirst, and spits blood, and epistaxis is sent out the speckle dermexanthesis.Selecting Herba Asteris Flaccidi for use is that little suffering, cold have heat-clearing and toxic substances removing because of its nature and flavor hardship, and the function that cough-relieving makes eye bright is controlled lung abscess, pneumonia, pulmonary tuberculosis.Selecting Pseudobulbus Bletillae (Rhizoma Bletillae) for use is that lung meridian is gone in cold, and tonifying the lung is arranged because of its property bitter but sweet flavor, hemostasis, and detumescence is given birth to and is seen, and holds back the function of skin ulcer, and control lung and hinder hemoptysis, epistaxis, incised wound is hemorrhage, swollen ulcer drug, ulcer pain, the soup fire is burnt, rhagadia manus et pedis.Select for use Radix Asparagi to be because its nature and flavor sweetness and bitterness is cold, go into lung, kidney channel, YIN nourishing is arranged, moisturize, lung heat clearing, the function of pathogenic fire reducing is controlled fever due to yin deficiency, and cough is spitted blood, consumptive lung disease, lung abscess, laryngopharynx swelling and pain is quenched one's thirst, constipation.Select for use Folium Mori to be because its property bitter but sweet flavor is cold, go into lung, Liver Channel, expelling wind and clearing away heat is arranged, the function of cooling blood for improving eyesight, the dispelling the wind and dampness pathogens heating, headache, conjunctival congestion, thirsty, cough due to lung-heat, migratory arthralgia, urticaria, lower limb elephatiasis.Select for use Cortex Moutan to be because its nature and flavor are arduous, the heart, liver, kidney channel are gone in cold, and heat clearing away is arranged, removing heat from blood, and blood, and the function of repercussive is controlled the pathogenic heat attacking blood system in febrile diseases, sends out speckle ， Jing Epilepsy, and tell, be defeated in battle, have blood in stool, the hectic fever due to YIN-deficiency consumptive fever, amenorrhea ， mass in the abdomen, carbuncle and ulcer is pounced on damage.It is sweet because of its nature and flavor, cold selecting Rhizoma Imperatae for use, goes into lung, stomach, small intestine meridian, and removing heat from blood is arranged, hemostasis, and heat clearing away, the diuretic function is controlled the calentura excessive thirst, spits blood epistaxis, lung-heat dyspnea with rapid respiration, gastric heat hiccup, gonorrhea, dysuria, edema, jaundice.Select for use Radix Codonopsis to be because its nature and flavor are sweet, flat, start with, the meridian of Foot-TAI YIN edema caused by disorder of QI, invigorating the spleen and replenishing QI is arranged, the function of promoting the production of body fluid is controlled weakness of the spleen and stomach, deficiency of both QI and blood, and fatigue and lack of strength, lack of appetite, thirsty, chronic diarrhea, proctoptosis.Selecting the Rhizoma Pinelliae for use is because of its nature and flavor suffering, and temperature is poisonous, goes into spleen, stomach warp, and drying dampness to eliminate phlegm is arranged, stopping nausea and vomiting by lowering the adverse flow of QI, and the function of dissolving lump and resolving mass is controlled the damp-phlegm cold drink, vomiting, regurgitation, cough with asthma abundant expectoration, chest and diaphragm distension, syncope due to accumulation of phlegm headache, dizzy sleeplessness, outer subduing inflammation.Select for use Radix Gentianae to be because its nature and flavor hardship is cold, go into liver, gallbladder meridian, the eliminating pathogen in the liver excess-fire is arranged, remove the function of damp-heat in lower-JIAO, treating the liver is manic through intenseness of heat ， Jing Epilepsy, encephalitis B, and headache, conjunctival congestion, pharyngalgia, jaundice, hematodiarrhoea, the carbuncle skin infection, scrotum swells and ache, the pudendum pruritus due to damp pathogen.Selecting Radix Saniculae Astrantifoliae for use is because of its property sweet and slightly bitter taste, and the function of invigorating the lung and the kidney is arranged, and controls pulmonary tuberculosis, lumbago due to renal deficiency.Selecting Radix Dipsaci for use is that tepor is gone into liver, kidney channel, and invigorating the liver and kidney is arranged because of its nature and flavor toil, reuniting the fractured tendons and bones, and the function of blood circulation regulating is controlled aching pain in waist and back, the foot and knee being feeble, vaginal bleeding during pregnancy, metrorrhagia, leukorrhagia, seminal emission, traumatic injury, incised wound, anal fistula, the carbuncle skin ulcer is swollen.Selecting the Radix Stemonae for use is that tepor is gone into lung meridian, and gentle lung qi is arranged because of its nature and flavor sweetness and bitterness, cough-relieving, and parasiticidal function is controlled the cough due to wind and cold, pertussis, pulmonary tuberculosis, old cough with asthma, ascarid, enterobiasis, skin scabies, eczema.Select for use Radix Gentianae Macrophyllae to be because its nature and flavor toil is flat, go into liver, stomach, gallbladder meridian, expelling wind and removing dampness and blood Shujin are arranged, the function of clearing away heat and promoting diuresis, the dispelling the wind and dampness pathogens arthralgia pain, the muscles and bones contracture, jaundice is had blood in stool, osteopyrexia and fever, children's's infantile malnutrition with fever, dysuria.Select for use Lignum Aquilariae Resinatum to be because its nature and flavor are arduous, temperature is gone into kidney, spleen, stomach warp, and the sending down the abnormal ascending QI warming middle-JIAO is arranged, and the function of warming the kidney improving inspiration by invigorating kidney-QI is controlled QI rising in reverse order and panted, vomiting singultus, abdominal distention, waist lacquer cold caused by deficiency, asthenia-cool of the large intestine, urine qi stranguria, man's cold sperm.Select for use Radix Platycodonis to be because its nature and flavor toil is flat, go into lung, stomach warp, lung qi dispersing gas is arranged out, the function of the evacuation of pus of eliminating the phlegm is controlled the exogenous cough, laryngopharynx swelling and pain, lung abscess vomiting pus, fullness in the chest and hypochondriac pain, dysentery stomachache.Selecting Radix Scrophulariae for use is that salty, lung, kidney channel are gone in cold, and YIN nourishing is arranged because of its nature and flavor hardship, pathogenic fire reducing, and relieving restlessness, the antidotal function is controlled the calentura excessive thirst, sends out speckle, the hectic fever due to YIN-deficiency consumptive fever, it is not peaceful to sleep night, spontaneous sweating, constipation is hindered in Tianjin, hematemesis and epistaxis, laryngopharynx swelling and pain, carbuncle, scrofula.Selecting Radix Stellariae for use is that liver, stomach warp are gone in cold, and the function of clearing away heat and cooling blood is arranged, and control the asthenia hectic fever due to YIN-deficiency, deficiency of YIN chronic malaria, children's's infantile malnutrition with fever weakness and emaciation because of its nature and flavor sweetness and bitterness.Select for use Depositum urinae preparatum to be because its nature and flavor are salty, cold, go into lung, kidney channel, the function of nourishing YIN to lower pathogenic fire is arranged, control the hectic fever due to YIN-deficiency consumptive fever, cough, hemoptysis, laryngopharynx swelling and pain, the food regurgitation of choking, seminal emission, nebulousurine, stranguria marked by chyluria, women's leucorrhea with red and white discharge.Select for use Pericarpium Metaplexis to be because its nature and flavor are salty, put down, the function of removing heat from the lung and dissipating phlegm is arranged, control cough with copious phlegm, dyspnea and cough due to the lung-wind syndrome with phlegm, pertussis ， Jing Epilepsy, measles without adequate eruption.Select for use Caulis Bambusae In Taenia to be because its nature and flavor are sweet, stomach, gallbladder meridian are gone in cold, and heat clearing away is arranged, and removing heat from blood reduces phlegm, and the antiemetic function is controlled dysphoria with smothery sensation vomiting, singultus, and the expectorant heat syndrome cough is breathed heavily, and spits blood epistaxis, metrorrhagia, malignant histocytosis, fetal movement ， Jing Epilepsy.Select for use Cordyceps to be because its nature and flavor are sweet, temperature is gone into lung, kidney two warps, and tonifying deficiency is arranged, and the function of beneficial vital essence is controlled phlegm retention and breathed heavily and cough, dyspnea due to deficiency, and consumptive disease is coughed, spitting of blood, spontaneous sweating, impotence and seminal emission, soreness of waist and knee joint, prolonged deficiency is multiple after being ill.Select for use Radix Rehmanniae Preparata to be because its nature and flavor are sweet, tepor is gone into liver, kidney channel, and YIN nourishing is arranged, and the function of enriching blood is controlled deficiency of YIN insufficiency of blood, the waist knee flaccidity, and the chronic cough hectic fever due to YIN-deficiency, seminal emission, metrorrhagia, menoxenia is quenched one's thirst, frequency of micturition, deafness, blurred vision.Select for use Concha Haliotidis to be because its nature and flavor are salty, flat, go into liver, kidney channel, suppressing the hyperactive liver and subsiding YANG is arranged, heat extraction, the function that makes eye bright is controlled wind-yang and up-boring, headache is dizzy, frightenedly jerks hectic fever due to YIN-deficiency consumptive fever, optic atrophy.Selecting Bulbus Fritillariae Cirrhosae for use is that lung meridian is gone in cold, and the lung moistening eliminating stagnation is arranged because of its property bitter but sweet flavor, and antitussive expectorant function is controlled cough due to consumptive disease, the spitting of blood of spitting, ambition pent-up, consumptive lung disease, lung abscess, goiter, scrofula, sore throat, acute mastitis.Select for use Radix Adenophorae to be because its nature and flavor are sweet, be slightly cold, attach to the lung and stomach meridians, nourishing YIN and clearing away lung-heat is arranged, reduce phlegm, the function of QI invigorating is controlled lung-heat type cough, deficiency of YIN phthisical cough, and dry cough expectorant is glutinous, deficiency of both vital energy and Yin, restlessness and fever with thirst.Select for use Poria to be because its property slightly sweet flavor is flat, go into the heart, spleen, lung meridian, eliminating dampness and diuresis is arranged, the strengthening the spleen stomach function regulating, the function of mind tranquilizing and the heart calming is controlled dysuria edema distending pain, the phlegm retention cough with dyspnea, the sound of vomiting of vomitting is had loose bowels, seminal emission, stranguria with turbid discharge, palpitation with fear, forgetful.Selecting Radix Angelicae Sinensis for use is that temperature is gone into the heart, liver, spleen channel, and benefiting blood and regulating blood circulation is arranged, menstruction regulating and pain relieving, the function of moisturizing laxation because of the sweet suffering of its nature and flavor, control menoxenia, amenorrhea stomachache ， mass in the abdomen knot is poly-, metrorrhagia, and headache due to deficiency of blood, dizzy, flaccidity syndrome and arthralgia syndrome, dryness of the intestine difficulty are just, and be heavy after the bloody dysentery, ulcer sores, incised wound, injury from falling down.Selecting the Radix Paeoniae Alba for use is that liver, spleen channel are gone in cold, and nourishing blood to suppress the hyperactive liver is arranged because of its nature and flavor picric acid, slow middle pain relieving, and yin fluid astringing is received the function of antiperspirant, controls the breast abdomen pain over the hypochondriac region, dysentery stomachache, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia.Select for use Radix Et Rhizoma Rhei to be because its nature and flavor hardship, cold is gone into stomach, large intestine, liver footpath, the poison of purging heat is arranged, removing mass stagnates, the function of clots absorbing blood is controlled the excess-heat constipation, and delirium is gone mad, the food stagnation feeling of fullness, dysentery from the beginning of, tenesmus, stasis of blood menolipsis Bi ， lumps in the chest and abdomen, the time row epidemic disease due to heat pathogen, sudden and violent swelling ophthalmalgia is spitted blood epistaxis, YANG jaundice, edema, stranguria with turbid discharge, it is red to urinate, the carbuncle and ulcer toxic swelling, furuncle, burn.Selecting Fructus Schisandrae Chinensis for use is that temperature is gone into lung, kidney channel, astringes the lung because of its nature and flavor acid, and nourishing kidney is promoted the production of body fluid, and receives antiperspirant, and the function of arresting seminal emission is controlled the deficiency of the lung and breathed with cough, and xerostomia is done thirsty, spontaneous perspiration, night sweat, impairment caused by overstrain weakness and emaciation, emission, chronic diarrhea chronic dysentery.Select for use Caulis et folium stauntoniae to be because it has heart tonifying, diuresis, analgesic function.Select for use Radix Ophiopogonis to be because its property sweet and slightly bitter taste is cold, go into lung, stomach, heart channel, nourishing YIN and moistening the lung is arranged, the relieving restlessness that clears away heart-fire, the function of reinforcing stomach reg fluid is controlled dryness of the lung dry cough, spits blood, spitting of blood, consumptive lung disease, lung abscess, the asthenia dysphoria with smothery sensation, clear thirsty, hinder in calentura Tianjin, dry mouth and throat, constipation.

The specific embodiment

Drug dose in the invention combination also is that the inventor draws through groping in a large number to sum up, and the consumption of each component all has curative effect preferably in following weight range.

Colla Corii Asini 10-20 gram Radixs Astragali 10-20 gram Indigo Naturaliss 10-15 grams

Radix Glycyrrhizae 6-10 gram Radix Rehmanniae 10-20 gram Herba Asteris Flaccidies 10-20 grams

Pseudobulbus Bletillae (Rhizoma Bletillae) 10-20 gram Radix Asparagi 8-12 gram Folium Mori 10-20 grams

Cortex Moutan 10-15 gram Rhizoma Imperataes 10-15 gram Radix Codonopsis 10-20 grams

The Rhizoma Pinelliae 10-15 cron gallbladders 8-12 gram Radix Saniculae Astrantifoliae 8-12 grams

Radix Dipsaci 10-20 gram Radixs Stemonae 10-20 gram Radix Gentianae Macrophyllae 10-20 grams

Lignum Aquilariae Resinatum 8-12 gram Radix Platycodoniss 10-15 gram Radix Scrophulariaes 10-15 grams

Radix Stellariae 10-20 gram Depositum urinae preparatum 4-8 gram Pericarpium Metaplexis 8-12 grams

Caulis Bambusae In Taenia 8-12 gram Cordyceps 4-8 gram Radix Rehmanniae Preparata 8-12 grams

Concha Haliotidis 8-15 gram Bulbus Fritillariae Cirrhosaes 8-15 gram Radix Adenophoraes 10-20 grams

Poria 8-12 gram Radix Angelicae Sinensis 10-15 gram Radix Paeoniae Albas 10-15 grams

Radix Et Rhizoma Rhei 4-8 gram Fructus Schisandrae Chinensis 10-15 gram Caulis et folium stauntoniaes 8-12 grams

Radix Ophiopogonis 8-12 grams

Be preferably

The Colla Corii Asini 15 gram Radixs Astragali 15 gram Indigo Naturaliss 12 grams

Radix Glycyrrhizae 8 gram Radix Rehmanniae 15 gram Herba Asteris Flaccidies 15 grams

Pseudobulbus Bletillae (Rhizoma Bletillae) 15 gram Radix Asparagi 10 gram Folium Mori 15 grams

Cortex Moutan 12 gram Rhizoma Imperataes 12 gram Radix Codonopsis 15 grams

The Rhizoma Pinelliae 12 cron gallbladders 10 gram Radix Saniculae Astrantifoliae 10 grams

The Radix Dipsaci 15 gram Radixs Stemonae 15 gram Radix Gentianae Macrophyllae 15 grams

Lignum Aquilariae Resinatum 10 gram Radix Platycodoniss 12 gram Radix Scrophulariaes 12 grams

Radix Stellariae 15 gram Depositum urinae preparatum 6 gram Pericarpium Metaplexis 10 grams

Caulis Bambusae In Taenia 10 gram Cordyceps 6 gram Radix Rehmanniae Preparata 10 grams

Concha Haliotidis 12 gram Bulbus Fritillariae Cirrhosaes 12 gram Radix Adenophoraes 15 grams

The Poria 10 gram Radix Angelicae Sinensis 12 gram Radix Paeoniae Albas 12 grams

Radix Et Rhizoma Rhei 6 gram Fructus Schisandrae Chinensis 12 gram Caulis et folium stauntoniaes 10 grams

Radix Ophiopogonis 10 grams

Preparation method of the present invention is as follows

One, gets the raw materials ready

1, Colla Corii Asini: smash usefulness to pieces;

2, the Radix Astragali: choose clean impurity, remove residual root head and hollow the greater, be soaked in water, pull out, run through back section in time, dry;

3, Indigo Naturalis: choose decontamination, cross sieve;

4, Radix Glycyrrhizae: choose decontamination, clean, be soaked in water to eighty per cant when saturating, pull out, run through section, airing;

5, Radix Rehmanniae: get crude drug, remove impurity, clean, profit is cut sheet slightly, drying, and sieve removes chip;

6, Herba Asteris Flaccidi: all herbal medicine, Xia Qiu gathers, and dries in the shade;

7, Pseudobulbus Bletillae (Rhizoma Bletillae): choose decontamination, be soaked in water, pull out, it is suitable to humidity to dry in the air, section, drying;

8, Radix Asparagi: choose decontamination, washing is clean, and moistening is even to inside and outside humidity, cutting, drying;

9, Folium Mori: choose decontamination, rub with the hands brokenly, it is destemming to winnow with a dustpan, and sieve removes spare;

10, Cortex Moutan: choose decontamination, remove core, clean, run through, section is dried;

11, Rhizoma Imperatae: choose clean impurity, clean, little profit, cutting is dried, the clean chip of winnowing with a dustpan;

12, Radix Codonopsis: run through reed after cleaning silt, section or cutting are dried;

13, the Rhizoma Pinelliae: choose decontamination, sieve dedust bits;

14, Radix Gentianae: choose decontamination, remove residual stem, clean, run through the back cutting, dry;

15, Radix Saniculae Astrantifoliae: choose decontamination, moisten soft, the section, dry;

16, Radix Dipsaci: clean silt, remove the retained root head, run through the back section and dry, sieve anti-dandruff;

17, the Radix Stemonae: choose clean impurity, remove fibrous root, clean, run through the back cutting, dry;

18, Radix Gentianae Macrophyllae: choose decontamination, remove removing LU, soak slightly, run through section, dry;

19, Lignum Aquilariae Resinatum: outwash, be split into fritter, fine powder is smashed or be ground into to the time spent to pieces;

20, Radix Platycodonis: choose clean impurity, remove removing LU, clean and pull out, run through the back section, dry;

21, Radix Scrophulariae: choose clean impurity, remove removing LU, clean running through, section is dried;

22, Radix Stellariae: choose decontamination, go reed, wash, soak slightly and pull out, run through, section is dried;

23, Depositum urinae preparatum: remove impurity, break into fragment;

24, Pericarpium Metaplexis: cut off fruit stem, remove seed and floss hair;

25, Caulis Bambusae In Taenia: remove hard bamboo let, impurity, shake off the ash bits, rub Cheng Xiaotuan or cutting

26, Cordyceps: remove impurity;

27, Radix Rehmanniae Preparata: get Radix Rehmanniae and add yellow wine 30%, mix thoroughly in the steaming device, steam to inside and outside black profit, taking-up is dried;

28, Concha Haliotidis: clean and dry the knock fragment;

29, Bulbus Fritillariae Cirrhosae: choose decontamination, be soaked in water, pull out, moistening is peelled off the heart, dries;

30, Radix Adenophorae: remove fibrous root, clean, scrape off rough bark, drying;

31, Poria: be soaked in water, clean and to pull out, vexed after, cut into slices, dry;

32, Radix Angelicae Sinensis: choose roguing and sanction, clean, moistening dries in the air slightly to inside and outside humidity when suitable, and section is dried;

33, the Radix Paeoniae Alba: choose roguing and sanction, size separately is soaked in water to eighty per cant saturating, pulls out, and solarization is dried in the air, and profit is even to inside and outside humidity, section, drying;

34, Radix Et Rhizoma Rhei: choose clean impurity, big or small stepping, stewing profit is even to inside and outside humidity, cuts into slices or is cut into small pieces, dries;

35, Fructus Schisandrae Chinensis: sieve dedust bits, remove impurity, to put in the food steamer and steam thoroughly, taking-up is dried;

36, Caulis et folium stauntoniae: get rattan, the stem of Fructus Chaenomelis, remove impurity, soak, run through, section, drying;

37, Radix Ophiopogonis: choose clean impurity, be soaked in water, pull out, take out the heart after running through, clean again and dry.

Two, preparation

1, the preparation of decocting liquid

(1) with the Colla Corii Asini of described weight, the Radix Astragali, Indigo Naturalis, Radix Glycyrrhizae, Radix Rehmanniae, Herba Asteris Flaccidi, Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Asparagi, Folium Mori, Cortex Moutan, Rhizoma Imperatae, Radix Codonopsis, the Rhizoma Pinelliae, Radix Gentianae, Radix Saniculae Astrantifoliae, Radix Dipsaci, the Radix Stemonae, Radix Gentianae Macrophyllae, Lignum Aquilariae Resinatum, Radix Platycodonis, Radix Scrophulariae, Radix Stellariae, Depositum urinae preparatum, Pericarpium Metaplexis, Caulis Bambusae In Taenia, Cordyceps, Radix Rehmanniae Preparata, Concha Haliotidis, Bulbus Fritillariae Cirrhosae, Radix Adenophorae, Poria, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Radix Et Rhizoma Rhei, Fructus Schisandrae Chinensis, Caulis et folium stauntoniae, Radix Ophiopogonis decocts with water, add for the first time 2 times of amounts that water is crude drug weight, intense fire decocts boiling 30 minutes, reuse slow fire boiling 20 minutes, filter time decoction liquor of promptly winning, for obeying liquid patient's morning.

(2) medicinal residues after the filtration for the first time add 1.5 times of amounts that water is medicinal residues weight, decoct boiling, and reuse slow fire boiling 20 minutes is filtered and promptly got decoction liquor for the second time, is the liquid of taking medicine patient's evening.

2, capsular preparation

Colla Corii Asini with described weight, the Radix Astragali, Indigo Naturalis, Radix Glycyrrhizae, Radix Rehmanniae, Herba Asteris Flaccidi, Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Asparagi, Folium Mori, Cortex Moutan, Rhizoma Imperatae, Radix Codonopsis, the Rhizoma Pinelliae, Radix Gentianae, Radix Saniculae Astrantifoliae, Radix Dipsaci, the Radix Stemonae, Radix Gentianae Macrophyllae, Lignum Aquilariae Resinatum, Radix Platycodonis, Radix Scrophulariae, Radix Stellariae, Depositum urinae preparatum, Pericarpium Metaplexis, Caulis Bambusae In Taenia, Cordyceps, Radix Rehmanniae Preparata, Concha Haliotidis, Bulbus Fritillariae Cirrhosae, Radix Adenophorae, Poria, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Radix Et Rhizoma Rhei, Fructus Schisandrae Chinensis, Caulis et folium stauntoniae, Radix Ophiopogonis adds decocting twice, each amount of water was for soaking powder, intense fire decocts boiling, slow fire boiling 20 minutes, merge decoction liquor twice, it is 1.35 extractum that filtering and concentrating becomes proportion, add 90-95% ethanol and carry out precipitate with ethanol, reclaim ethanol and be concentrated in 45-50 ℃ of dryings down, it is ground into powder, incapsulates.

3, the preparation of tablet

Colla Corii Asini with described weight, the Radix Astragali, Indigo Naturalis, Radix Glycyrrhizae, Radix Rehmanniae, Herba Asteris Flaccidi, Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Asparagi, Folium Mori, Cortex Moutan, Rhizoma Imperatae, Radix Codonopsis, the Rhizoma Pinelliae, Radix Gentianae, Radix Saniculae Astrantifoliae, Radix Dipsaci, the Radix Stemonae, Radix Gentianae Macrophyllae, Lignum Aquilariae Resinatum, Radix Platycodonis, Radix Scrophulariae, Radix Stellariae, Depositum urinae preparatum, Pericarpium Metaplexis, Caulis Bambusae In Taenia, Cordyceps, Radix Rehmanniae Preparata, Concha Haliotidis, Bulbus Fritillariae Cirrhosae, Radix Adenophorae, Poria, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Radix Et Rhizoma Rhei, Fructus Schisandrae Chinensis, Caulis et folium stauntoniae, Radix Ophiopogonis decocts with water twice, add for the first time 6 times of amounts that water is crude drug weight, decocted 1.5 hours, add for the second time 4 times of amounts that water is crude drug weight, decocted 1 hour, merging the secondary decoction liquor, to be condensed into proportion be 1.35 extractum, ethanol with extractum adding 90-95%, stir, precipitation, reclaim ethanol and concentrated, and it is dry down at 45-50 ℃, be ground into powder, add the adjuvant compacting in flakes.

4, particulate preparation

Colla Corii Asini with described weight, the Radix Astragali, Indigo Naturalis, Radix Glycyrrhizae, Radix Rehmanniae, Herba Asteris Flaccidi, Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Asparagi, Folium Mori, Cortex Moutan, Rhizoma Imperatae, Radix Codonopsis, the Rhizoma Pinelliae, Radix Gentianae, Radix Saniculae Astrantifoliae, Radix Dipsaci, the Radix Stemonae, Radix Gentianae Macrophyllae, Lignum Aquilariae Resinatum, Radix Platycodonis, Radix Scrophulariae, Radix Stellariae, Depositum urinae preparatum, Pericarpium Metaplexis, Caulis Bambusae In Taenia, Cordyceps, Radix Rehmanniae Preparata, Concha Haliotidis, Bulbus Fritillariae Cirrhosae, Radix Adenophorae, Poria, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Radix Et Rhizoma Rhei, Fructus Schisandrae Chinensis, Caulis et folium stauntoniae, Radix Ophiopogonis decocts with water twice, add for the first time 6 times of amounts that water is crude drug weight, decocted 1.5 hours, add for the second time 4 times of amounts that water is crude drug weight, decocted 1 hour, merging the secondary decoction liquor, to be condensed into proportion be 1.35 extractum, ethanol with extractum adding 90-95%, stir, precipitation, reclaim ethanol and concentrated, dry down at 45-50 ℃, add adjuvant, make granule.

5, the preparation of unguentum

Colla Corii Asini with described weight, the Radix Astragali, Indigo Naturalis, Radix Glycyrrhizae, Radix Rehmanniae, Herba Asteris Flaccidi, Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Asparagi, Folium Mori, Cortex Moutan, Rhizoma Imperatae, Radix Codonopsis, the Rhizoma Pinelliae, Radix Gentianae, Radix Saniculae Astrantifoliae, Radix Dipsaci, the Radix Stemonae, Radix Gentianae Macrophyllae, Lignum Aquilariae Resinatum, Radix Platycodonis, Radix Scrophulariae, Radix Stellariae, Depositum urinae preparatum, Pericarpium Metaplexis, Caulis Bambusae In Taenia, Cordyceps, Radix Rehmanniae Preparata, Concha Haliotidis, Bulbus Fritillariae Cirrhosae, Radix Adenophorae, Poria, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Radix Et Rhizoma Rhei, Fructus Schisandrae Chinensis, Caulis et folium stauntoniae, Radix Ophiopogonis decocts with water twice, add for the first time 6 times of amounts that water is crude drug weight, decocted 1.5 hours, add for the second time 4 times of amounts that water is crude drug, decocted 1 hour, merging the secondary decoction liquor, to be condensed into proportion be 1.35 extractum.

The active component of medicine of the present invention can add preparation required various conventional adjuvant during different dosage form, is prepared into any common peroral dosage form with the method for Chinese medicinal of routine, as tablet, capsule, granule, unguentum etc.

Medicine of the present invention has clearing away heat and cooling blood, the stasis of blood clearly of invigorating blood circulation, and the function of promoting pus discharge and tissue regeneration strengthening is used for the treatment of pulmonary tuberculosis, good effect, instant effect is difficult for recurrence.

Below further sets forth the beneficial effect of medicine of the present invention by testing example, these are tested and routinely comprise that the animal toxicity test of medicine of the present invention and clinical observation test.

The animal toxicity test data of [test example 1] medicine of the present invention:

1, get 40 of new zealand rabbits, body weight 2.0-2.5kg, male and female dual-purpose are divided into two groups, and 20 every, wherein one group is the overdose test group, and another group is the normal amount test group.

2, the overdose group is 15ml/kg, and the normal amount group is 10ml%, and administering mode is the administration by gavage administration, and every day is secondary sooner or later, serve on a week, observes the administration reaction every day, and the result shows that the movable diet of two groups of rabbit is normal, and medicine does not have bad toxic and side effects.

The clinical observation material of [test example 2] medicine of the present invention

1, physical data:

Accept out-patient's 360 examples for medical treatment, 15-20 years old 30 age example, 21-30 years old 96 example, 31-40 years old 79 example, 41-50 years old 72 example, 83 examples more than 50 years old.

2, diagnostic criteria:

Light shape pulmonary tuberculosis: the light-duty pulmonary tuberculosis in 1 year of fall ill, patient's cough is spat blood, hectic fever, night sweat, restlessness and thirst is breathed hard and is breathed with cough.

Heavy shape pulmonary tuberculosis: medical history is more than 1 year, patient's cough, and sputum mixed with blood, expectorant matter is thick dense, osteopyrexia and fever, insomnia and dreamful sleep chokes that it is out of breath to cough, tugging pain over the chest and hypochondrium, red tongue, thready and rapid pulse.

3, Therapeutic Method:

Decocting liquid: every day twice, herbal decoction decocts and to take routinely, sooner or later services once, and 20 days is a course of treatment, course of treatment of light shape, heavy three courses of treatment.

Capsule: every day three times, each 12,20 days is a course of treatment, light-duty two courses of treatment, heavy three courses of treatment.

Tablet: every day three times, each 10,20 days is a course of treatment, light-duty two courses of treatment, reopens three courses of treatment.

Granule: every day three times, each two bags of 15g, 20 days is a course of treatment, light-duty two courses of treatment, heavy three courses of treatment.

4, efficacy assessment standard:

Produce effects: the degree type pulmonary tuberculosis after treatment, patient's transference cure, it is normal that patient's body constitution is recovered, and follows up a case by regular visits to 1-2 years no recidivists.

Take a turn for the better: the degree type pulmonary tuberculosis is after treatment, and symptom obviously alleviates, and it is normal that patient's body constitution is recovered substantially.

Invalid: it is good not reach the improvement standard.

5, therapeutic outcome: see the following form

In the treatment of two courses of treatment, with light-duty pulmonary tuberculosis 228 examples of Drug therapy of the present invention, produce effects 213 is imitated, and total effective rate is 99.12%, and in the treatment of three courses of treatment, with heavy pulmonary tuberculosis 132 examples of Drug therapy of the present invention, produce effects 112 examples, total effective rate is 95.45%.

Claims (3)

1. treat phthisical medicine for one kind, it is characterized in that: it is made up of the crude drug in the following weight range:

Colla Corii Asini 10-20 gram Radixs Astragali 10-20 gram Indigo Naturaliss 10-15 grams

Radix Glycyrrhizae 6-10 gram Radix Rehmanniae 10-20 gram Herba Asteris Flaccidies 10-20 grams

Pseudobulbus Bletillae (Rhizoma Bletillae) 10-20 gram Radix Asparagi 8-12 gram Folium Mori 10-20 grams

Cortex Moutan 10-15 gram Rhizoma Imperataes 10-15 gram Radix Codonopsis 10-20 grams

The Rhizoma Pinelliae 10-15 cron gallbladders 8-12 gram Radix Saniculae Astrantifoliae 8-12 grams

Radix Dipsaci 10-20 gram Radixs Stemonae 10-20 gram Radix Gentianae Macrophyllae 10-20 grams

Lignum Aquilariae Resinatum 8-12 gram Radix Platycodoniss 10-15 gram Radix Scrophulariaes 10-15 grams

Radix Stellariae 10-20 gram Depositum urinae preparatum 4-8 gram Pericarpium Metaplexis 8-12 grams

Caulis Bambusae In Taenia 8-12 gram Cordyceps 4-8 gram Radix Rehmanniae Preparata 8-12 grams

Concha Haliotidis 8-15 gram Bulbus Fritillariae Cirrhosaes 8-15 gram Radix Adenophoraes 10-20 grams

Poria 8-12 gram Radix Angelicae Sinensis 10-15 gram Radix Paeoniae Albas 10-15 grams

Radix Et Rhizoma Rhei 4-8 gram Fructus Schisandrae Chinensis 10-15 gram Caulis et folium stauntoniaes 8-12 grams

Radix Ophiopogonis 8-12 grams.

2. medicine according to claim 1, wherein the consumption of each crude drug is:

The Colla Corii Asini 15 gram Radixs Astragali 15 gram Indigo Naturaliss 12 grams

Radix Glycyrrhizae 8 gram Radix Rehmanniae 15 gram Herba Asteris Flaccidies 15 grams

Pseudobulbus Bletillae (Rhizoma Bletillae) 15 gram Radix Asparagi 10 gram Folium Mori 15 grams

Cortex Moutan 12 gram Rhizoma Imperataes 12 gram Radix Codonopsis 15 grams

The Rhizoma Pinelliae 12 cron gallbladders 10 gram Radix Saniculae Astrantifoliae 10 grams

The Radix Dipsaci 15 gram Radixs Stemonae 15 gram Radix Gentianae Macrophyllae 15 grams

Lignum Aquilariae Resinatum 10 gram Radix Platycodoniss 12 gram Radix Scrophulariaes 12 grams

Radix Stellariae 15 gram Depositum urinae preparatum 6 gram Pericarpium Metaplexis 10 grams

Caulis Bambusae In Taenia 10 gram Cordyceps 6 gram Radix Rehmanniae Preparata 10 grams

Concha Haliotidis 12 gram Bulbus Fritillariae Cirrhosaes 12 gram Radix Adenophoraes 15 grams

The Poria 10 gram Radix Angelicae Sinensis 12 gram Radix Paeoniae Albas 12 grams

Radix Et Rhizoma Rhei 6 gram Fructus Schisandrae Chinensis 12 gram Caulis et folium stauntoniaes 10 grams

Radix Ophiopogonis 10 grams.

3. according to the preparation method of claim 1 or 2 described medicines, it is characterized in that: it comprises the following steps:

(1) gets the raw materials ready

(1) Colla Corii Asini: smash usefulness to pieces;

(2) Radix Astragali: choose clean impurity, remove residual root head and hollow the greater, be soaked in water, pull out, run through back section in time, dry;

(3) Indigo Naturalis: choose decontamination, cross sieve;

(4) Radix Glycyrrhizae: choose decontamination, clean, be soaked in water to eighty per cant when saturating, pull out, run through section, airing;

(5) Radix Rehmanniae: get crude drug, remove impurity, clean, profit is cut sheet slightly, drying, and sieve removes chip;

(6) Herba Asteris Flaccidi: all herbal medicine, Xia Qiu gathers, and dries in the shade;

(7) Pseudobulbus Bletillae (Rhizoma Bletillae): choose decontamination, be soaked in water, pull out, it is suitable to humidity to dry in the air, section, drying;

(8) Radix Asparagi: choose decontamination, washing is clean, and moistening is even to inside and outside humidity, cutting, drying;

(9) Folium Mori: choose decontamination, rub with the hands brokenly, it is destemming to winnow with a dustpan, and sieve removes spare;

(10) Cortex Moutan: choose decontamination, remove core, clean, run through, section is dried;

(11) Rhizoma Imperatae: choose clean impurity, clean, little profit, cutting is dried, the clean chip of winnowing with a dustpan;

(12) Radix Codonopsis: run through reed after cleaning silt, section or cutting are dried;

(13) Rhizoma Pinelliae: choose decontamination, sieve dedust bits;

(14) Radix Gentianae: choose decontamination, remove residual stem, clean, run through the back cutting, dry;

(15) Radix Saniculae Astrantifoliae: choose decontamination, moisten soft, the section, dry;

(16) Radix Dipsaci: clean silt, remove the retained root head, run through the back section and dry, sieve anti-dandruff;

(17) Radix Stemonae: choose clean impurity, remove fibrous root, clean, run through the back cutting, dry;

(18) Radix Gentianae Macrophyllae: choose decontamination, remove removing LU, soak slightly, run through section, dry;

(19) Lignum Aquilariae Resinatum: outwash, be split into fritter, fine powder is smashed or be ground into to the time spent to pieces;

(20) Radix Platycodonis: choose clean impurity, remove removing LU, clean and pull out, run through the back section, dry;

(21) Radix Scrophulariae: choose clean impurity, remove removing LU, clean running through, section is dried;

(22) Radix Stellariae: choose decontamination, go reed, wash, soak slightly and pull out, run through, section is dried;

(23) Depositum urinae preparatum: remove impurity, break into fragment;

(24) Pericarpium Metaplexis: cut off fruit stem, remove seed and floss hair;

(25) Caulis Bambusae In Taenia: remove hard bamboo let, impurity, shake off the ash bits, rub Cheng Xiaotuan or cutting

(26) Cordyceps: remove impurity;

(27) Radix Rehmanniae Preparata: get Radix Rehmanniae and add yellow wine 30%, mix thoroughly in the steaming device, steam to inside and outside black profit, taking-up is dried;

(28) Concha Haliotidis: clean and dry the knock fragment;

(29) Bulbus Fritillariae Cirrhosae: choose decontamination, be soaked in water, pull out, moistening is peelled off the heart, dries;

(30) Radix Adenophorae: remove fibrous root, clean, scrape off rough bark, drying;

(31) Poria: be soaked in water, clean and to pull out, vexed after, cut into slices, dry;

(32) Radix Angelicae Sinensis: choose roguing and sanction, clean, moistening dries in the air slightly to inside and outside humidity when suitable, and section is dried;

(33) Radix Paeoniae Alba: choose roguing and sanction, size separately is soaked in water to eighty per cant saturating, pulls out, and solarization is dried in the air, and profit is even to inside and outside humidity, section, drying;

(34) Radix Et Rhizoma Rhei: choose clean impurity, big or small stepping, stewing profit is even to inside and outside humidity, cuts into slices or is cut into small pieces, dries;

(35) Fructus Schisandrae Chinensis: sieve dedust bits, remove impurity, to put in the food steamer and steam thoroughly, taking-up is dried;

(36) Caulis et folium stauntoniae: get rattan, the stem of Fructus Chaenomelis, remove impurity, soak, run through, section, drying;

(37) Radix Ophiopogonis: choose clean impurity, be soaked in water, pull out, take out the heart after running through, clean again and dry;

(2) preparation

1, the preparation of decocting liquid

1. with the Colla Corii Asini of described weight, the Radix Astragali, Indigo Naturalis, Radix Glycyrrhizae, Radix Rehmanniae, Herba Asteris Flaccidi, Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Asparagi, Folium Mori, Cortex Moutan, Rhizoma Imperatae, Radix Codonopsis, the Rhizoma Pinelliae, Radix Gentianae, Radix Saniculae Astrantifoliae, Radix Dipsaci, the Radix Stemonae, Radix Gentianae Macrophyllae, Lignum Aquilariae Resinatum, Radix Platycodonis, Radix Scrophulariae, Radix Stellariae, Depositum urinae preparatum, Pericarpium Metaplexis, Caulis Bambusae In Taenia, Cordyceps, Radix Rehmanniae Preparata, Concha Haliotidis, Bulbus Fritillariae Cirrhosae, Radix Adenophorae, Poria, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Radix Et Rhizoma Rhei, Fructus Schisandrae Chinensis, Caulis et folium stauntoniae, Radix Ophiopogonis decocts with water, add for the first time 2 times of amounts that water is crude drug weight, intense fire decocts boiling 30 minutes, reuse slow fire boiling 20 minutes, filter time decoction liquor of promptly winning, for obeying liquid patient's morning;

2. the medicinal residues after will filtering for the first time add 1.5 times of amounts that water is medicinal residues weight, decoct boiling, and reuse slow fire boiling 20 minutes is filtered and promptly got decoction liquor for the second time, is the liquid of taking medicine patient's evening;

(2) capsular preparation

Colla Corii Asini with described weight, the Radix Astragali, Indigo Naturalis, Radix Glycyrrhizae, Radix Rehmanniae, Herba Asteris Flaccidi, Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Asparagi, Folium Mori, Cortex Moutan, Rhizoma Imperatae, Radix Codonopsis, the Rhizoma Pinelliae, Radix Gentianae, Radix Saniculae Astrantifoliae, Radix Dipsaci, the Radix Stemonae, Radix Gentianae Macrophyllae, Lignum Aquilariae Resinatum, Radix Platycodonis, Radix Scrophulariae, Radix Stellariae, Depositum urinae preparatum, Pericarpium Metaplexis, Caulis Bambusae In Taenia, Cordyceps, Radix Rehmanniae Preparata, Concha Haliotidis, Bulbus Fritillariae Cirrhosae, Radix Adenophorae, Poria, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Radix Et Rhizoma Rhei, Fructus Schisandrae Chinensis, Caulis et folium stauntoniae, Radix Ophiopogonis adds decocting twice, each amount of water was for soaking powder, intense fire decocts boiling, slow fire boiling 20 minutes, merge decoction liquor twice, it is 1.35 extractum that filtering and concentrating becomes proportion, add 90-95% ethanol and carry out precipitate with ethanol, reclaim ethanol and be concentrated in 45-50 ℃ of dryings down, it is ground into powder, incapsulates;

(3) preparation of tablet

Colla Corii Asini with described weight, the Radix Astragali, Indigo Naturalis, Radix Glycyrrhizae, Radix Rehmanniae, Herba Asteris Flaccidi, Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Asparagi, Folium Mori, Cortex Moutan, Rhizoma Imperatae, Radix Codonopsis, the Rhizoma Pinelliae, Radix Gentianae, Radix Saniculae Astrantifoliae, Radix Dipsaci, the Radix Stemonae, Radix Gentianae Macrophyllae, Lignum Aquilariae Resinatum, Radix Platycodonis, Radix Scrophulariae, Radix Stellariae, Depositum urinae preparatum, Pericarpium Metaplexis, Caulis Bambusae In Taenia, Cordyceps, Radix Rehmanniae Preparata, Concha Haliotidis, Bulbus Fritillariae Cirrhosae, Radix Adenophorae, Poria, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Radix Et Rhizoma Rhei, Fructus Schisandrae Chinensis, Caulis et folium stauntoniae, Radix Ophiopogonis decocts with water twice, add for the first time 6 times of amounts that water is crude drug weight, decocted 1.5 hours, add for the second time 4 times of amounts that water is crude drug weight, decocted 1 hour, merging the secondary decoction liquor, to be condensed into proportion be 1.35 extractum, ethanol with extractum adding 90-95%, stir, precipitation, reclaim ethanol and concentrated, and it is dry down at 45-50 ℃, be ground into powder, add the adjuvant compacting in flakes;

(4) particulate preparation

Colla Corii Asini with described weight, the Radix Astragali, Indigo Naturalis, Radix Glycyrrhizae, Radix Rehmanniae, Herba Asteris Flaccidi, Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Asparagi, Folium Mori, Cortex Moutan, Rhizoma Imperatae, Radix Codonopsis, the Rhizoma Pinelliae, Radix Gentianae, Radix Saniculae Astrantifoliae, Radix Dipsaci, the Radix Stemonae, Radix Gentianae Macrophyllae, Lignum Aquilariae Resinatum, Radix Platycodonis, Radix Scrophulariae, Radix Stellariae, Depositum urinae preparatum, Pericarpium Metaplexis, Caulis Bambusae In Taenia, Cordyceps, Radix Rehmanniae Preparata, Concha Haliotidis, Bulbus Fritillariae Cirrhosae, Radix Adenophorae, Poria, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Radix Et Rhizoma Rhei, Fructus Schisandrae Chinensis, Caulis et folium stauntoniae, Radix Ophiopogonis decocts with water twice, add for the first time 6 times of amounts that water is crude drug weight, decocted 1.5 hours, add for the second time 4 times of amounts that water is crude drug weight, decocted 1 hour, merging the secondary decoction liquor, to be condensed into proportion be 1.35 extractum, ethanol with extractum adding 90-95%, stir, precipitation, reclaim ethanol and concentrated, dry down at 45-50 ℃, add adjuvant, make granule;

(5) preparation of unguentum

Colla Corii Asini with described weight, the Radix Astragali, Indigo Naturalis, Radix Glycyrrhizae, Radix Rehmanniae, Herba Asteris Flaccidi, Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Asparagi, Folium Mori, Cortex Moutan, Rhizoma Imperatae, Radix Codonopsis, the Rhizoma Pinelliae, Radix Gentianae, Radix Saniculae Astrantifoliae, Radix Dipsaci, the Radix Stemonae, Radix Gentianae Macrophyllae, Lignum Aquilariae Resinatum, Radix Platycodonis, Radix Scrophulariae, Radix Stellariae, Depositum urinae preparatum, Pericarpium Metaplexis, Caulis Bambusae In Taenia, Cordyceps, Radix Rehmanniae Preparata, Concha Haliotidis, Bulbus Fritillariae Cirrhosae, Radix Adenophorae, Poria, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Radix Et Rhizoma Rhei, Fructus Schisandrae Chinensis, Caulis et folium stauntoniae, Radix Ophiopogonis decocts with water twice, add for the first time 6 times of amounts that water is crude drug weight, decocted 1.5 hours, add for the second time 4 times of amounts that water is crude drug, decocted 1 hour, merging the secondary decoction liquor, to be condensed into proportion be 1.35 extractum.