CN103463449A - Traditional Chinese medicine composite used for treating haemorrhoids and preparation method and application thereof - Google Patents
Traditional Chinese medicine composite used for treating haemorrhoids and preparation method and application thereof Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine composite used for treating haemorrhoids and a preparation method and the application of the traditional Chinese medicine composite. The traditional Chinese medicine composite comprises, by weight, 10-20 parts of bletilla striata, 5-15 parts of dahurian patrinia herbs, 10-20 parts of honeysuckle, 10-20 parts of herba cepbalanoplosis segeti, 10-20 parts of flos carthami, 10-20 parts of sophora japonica, 10-20 parts of sanguisorba officinalis, 5-15 parts of radix glycyrrhizae, 2-10 parts of dandelion, 2-10 parts of stir-baked squama manitis, 5-15 parts of salviae miltiorrhizae, 5-15 parts of angelica sinensis, 10-20 parts of paeonia suffruticosa, 5-15 parts of resina draconis, 5-15 parts of fritillaria cirrhosa, 5-15 parts of radix rehmanniae recen, 5-15 parts of red peony roots, 10-20 parts of agrimonia pilosa ledeb, 10-20 parts of radix isatidis, 10-20 parts of uniflower swisscentaury roots, 10-20 parts of herba ecliptae, 10-20 parts of semen cassiae and 10-20 parts of shuteria pampaniniana.
Description
Technical field
The invention belongs to medical technical field, be specifically related to a kind of Chinese medicine composition that is used for the treatment of hemorrhoid and preparation method thereof and its application.
Background technology
Hemorrhoid are the distinctive anorectal disease of the mankind, are also one of commonly encountered diseases, frequently-occurring disease.Expansion occurs and flexing forms soft vein agglomerate in venous plexus under patient's anal orifice and rectal intestine end mucosa and under anal canal skin, main clinical manifestation for having blood in stool, pain, edema, falling inflation, pruritus, secretions increase, the symptom such as deviate from, and easily cause the systemic diseases such as anemia, incarceration, necrosis, infection, gynecological inflammation, anal eczema, autonomic nervous dysfunction, have blood in stool with the passing of time, can cause anemia in various degree, hemorrhagic shock even appears, threat to life; Hemorrhoid are downright bad, infect when serious, can cause systemic infection through the blood system, and consequence is serious, and it is improper to prevent and treat, and will have a strong impact on patient's life, work, study and health.
Reconnaissance information shows, the sickness rate of anorectal disease is 59.1%, and wherein, hemorrhoid occupy 87.25% of all anal and intestinal diseases, and internal hemorrhoid accounts for again 52.19% of all anal and intestinal diseases.The hemorrhoid sickness rate of female patient is 67%, and male patient's hemorrhoid sickness rate is 53.9%, and ill comparatively common with 20-40 year age bracket, and with advancing age and the hemorrhoid prevalence increases gradually and the state of an illness progressively increases the weight of.
According to the site of pathological change of hemorrhoid, hemorrhoid are divided into to internal hemorrhoid, external hemorrhoid and mixed hemorrhoids (or claiming mixed hemorrhoid) three types.
Internal hemorrhoid is born on the anus tooth trace, and that position has is shallow, have dark.According to pathological change and the evolution of internal hemorrhoid, internal hemorrhoid is divided into to three periods, comprise initial stage (first phase), mid-term (second phase) and later stage (three phases).The blood stasis at internal hemorrhoid initial stage is very little, the matter softness, and hemorrhoid face cerise or livid purple color, often hemorrhage because of when stool friction, a hemorrhage or line is as arrow, or drop is endlessly, pain without doubt, and blood stasis is not deviate from outside anus yet; The blood stasis in internal hemorrhoid mid-term is larger, during stool, can deviate from outside anus, can recover voluntarily after an action of the bowels, and how much indefinite the amount of having blood in stool is; The blood stasis in internal hemorrhoid later stage is deviate from anus when stool, very when coughing, walking or standing for a long time, also can deviate from, and after deviating from, can not reply voluntarily, must return with hand push, or could reply after flat crouching; And often deviate to be difficult for to reset, the blood stasis quality is harder, surperficial micro-band canescence, also, because blood stasis increases, cause dyschesia, dysuria; Or, because stool bleeds too much, cause deficiency of both QI and blood, and shallow complexion, spirit is tired; Or live anus because of the blood stasis embedding, and can not bounce back, form strangulation, swell and ache, fester, necrosis; Or because suppurating, thereby secondary anal fistula.
External hemorrhoid is positioned at below the anus tooth trace, and take pain, lump is cardinal symptom, around anus long have differ in size, skin tag that shape differs.According to its pathological characteristic difference, be divided into four kinds of varicosis external hemorrhoid, connective tissue external hemorrhoid, thrombosed external hemorrhoid and inflammatory external hemorrhoids.Wherein, the most common with inflammatory external hemorrhoid, main manifestations is anus edge skin fold projection, and red and swollen heat pain, edema, obviously congested, have tenderness, and during defecation, pain increases the weight of, and a small amount of secretions is arranged, or with general malaise and heating.
Mixed hemorrhoid has the mixed hemorrhoids double characteristic concurrently, clinically take mucous membrane of rectum and skin is deviate from, falling inflation, pain, repeated infection are cardinal symptom, and the internal hemorrhoid growth site often is connected with external hemorrhoid.
Chinese medicine is thought, hemorrhoid are that yin-Yang imbalance, internal organs QI and blood deficiently add that wind, cold, dry, heat and feelings will internal injury, daily life do not save again, due to the factor such as professional, cause patient's disorder of QI and blood, blockage of meridian, congestion to be made a bet, and take damp invasion of lower energizer as many, wet dimerization heat, the corruption of intenseness of heat meat, thermal resistance blood stasis, injury of blood collaterals by heat.
At present, the treatment for the treatment of hemorrhoid focuses on eliminating and relief of symptoms, and pays the utmost attention to expectant treatment.The method for the treatment of hemorrhoid comprises operative therapy, oral medicine therapy and topical medication.Wherein, operative therapy comprises operation, ultralow temperature therapy, superhigh temperature therapy and injection treatment etc., mainly for obstinate or formed larger mixed hemorrhoid or garland hemorrhoid patient, and exist the patient suffering, easily produce complication, treatment not thoroughly, the defects such as easily recurrence, somewhat expensive.Oral medicine therapy and topical medication comprise oral or external Western medicine or Chinese medicine, mainly by medicine, soften stool, the impact of stool to the anus blood stasis while reducing defecation, with the reduction of patient misery, as MAYINGLONG MUSK HEMORRHOID UNGUENTUM, anus are safe, the hemorrhoid infections disappears, hemorrhoid irrigation, anti-inflammatory anti-itch electuary etc., but oral medicine therapy and topical medication exist take effect slow, difficult eliminate focus, treatment not thoroughly, easily recurrence, the defects such as cure rate is low, curative effect is undesirable.
In addition, internal treatments' (as medicines such as removing heat from blood Dihuang Decoction, Herba Cistanches pill for smoothing intestines) and the external treatmenies (as Chinese medicine demibain, external-applied ointment, external medicinal liquid, suppository are received anus etc.) of adopting, to alleviate and to treat that hemorrhoid are postoperative to swell and ache, mainly realize aforementioned purpose by effects such as heat-clearing and toxic substances removing, QI invigorating dampness removing, loosening bowel to relieve constipation, blood circulation promoting and blood stasis dispelling, pain relievings more.
For this reason, be badly in need of a kind of determined curative effect of research, relapse rate is low, patient compliance is high hemorrhoid treating medicine.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine composition that is used for the treatment of hemorrhoid, raw material composition and the parts by weight thereof of making described Chinese medicine composition effective ingredient are: Pseudobulbus Bletillae (Rhizoma Bletillae) 10-20 part, Herba Patriniae 5-15 part, Flos Lonicerae 10-20 part, little Thistle 10-20 part, Flos Carthami 10-20 part, Flos Sophorae 10-20 part, Radix Sanguisorbae 10-20 part, Radix Glycyrrhizae 5-15 part, Herba Taraxaci 2-10 part, stir-baked SQUAMA MANITIS 2-10 part, Radix Salviae Miltiorrhizae 5-15 part, Radix Angelicae Sinensis 5-15 part, Cortex Moutan 10-20 part, Sanguis Draxonis 5-15 part, Bulbus Fritillariae Cirrhosae 5-15 part, Radix Rehmanniae 5-15 part, Radix Paeoniae Rubra 5-15 part, Herba Agrimoniae 10-20 part, Radix Isatidis 10-20 part, Radix Rhapontici root 10-20 part, Herba Ecliptae 10-20 part, Semen Cassiae 10-20 part, HERBA SHUTERIAE 10-20 part.
In the preferred technical solution of the present invention, raw material composition and the parts by weight thereof of making described Chinese medicine composition effective ingredient are: Pseudobulbus Bletillae (Rhizoma Bletillae) 12-18 part, Herba Patriniae 8-12 part, Flos Lonicerae 12-18 part, little Thistle 12-18 part, Flos Carthami 12-18 part, Flos Sophorae 12-18 part, Radix Sanguisorbae 12-18 part, Radix Glycyrrhizae 8-12 part, Herba Taraxaci 4-8 part, stir-baked SQUAMA MANITIS 4-8 part, Radix Salviae Miltiorrhizae 8-12 part, Radix Angelicae Sinensis 8-12 part, Cortex Moutan 12-18 part, Sanguis Draxonis 8-12 part, Bulbus Fritillariae Cirrhosae 8-12 part, Radix Rehmanniae 8-12 part, Radix Paeoniae Rubra 8-12 part, Herba Agrimoniae 12-18 part, Radix Isatidis 12-18 part, Radix Rhapontici root 12-18 part, Herba Ecliptae 12-18 part, Semen Cassiae 12-18 part, HERBA SHUTERIAE 12-18 part.
In the preferred technical solution of the present invention, raw material composition and the parts by weight thereof of making described Chinese medicine composition effective ingredient are: 15 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 10 parts of Herba Patriniae, 15 parts of 15 parts of ， little Thistle of Flos Lonicerae, 15 parts, Flos Carthami, 15 parts, Flos Sophorae, 15 parts of Radix Sanguisorbaes, 10 parts, Radix Glycyrrhizae, 5 parts of Herba Taraxacis, 5 parts of stir-baked SQUAMA MANITISs, 10 parts of Radix Salviae Miltiorrhizaes, 10 parts of Radix Angelicae Sinensis, 15 parts of Cortex Moutans, 10 parts of Sanguis Draxonis, 10 parts of Bulbus Fritillariae Cirrhosaes, 10 parts of Radix Rehmanniae, 10 parts of Radix Paeoniae Rubra, 15 parts of Herba Agrimoniaes, 15 parts of Radix Isatidis, 15 parts of Radix Rhapontici roots, 15 parts of Herba Ecliptaes, 15 parts of Semen Cassiaes, 15 parts of HERBA SHUTERIAEs.
In the preferred technical solution of the present invention, Chinese medicine composition of the present invention is selected from any or its combination of oral formulations, external preparation.
In the preferred technical solution of the present invention, described oral formulations is selected from any of oral liquid, tablet, capsule, granule, pill, powder, syrup, mixture, spray, distillate medicinal water, medicinal tea.
In the preferred technical solution of the present invention, described external preparation is selected from any of gel, unguentum, liniment, lotion, suppository, liniment, fumigant, emplastrum, solidifying unguentum, ointment.
In the preferred technical solution of the present invention, described Chinese medicine composition is selected from any of oral liquid, tablet, capsule, granule, pill, powder, syrup, mixture, spray, distillate medicinal water, medicinal tea, gel, unguentum, liniment, lotion, liniment, fumigant, suppository, emplastrum, solidifying unguentum, ointment.
Can adopt preparation technique means well known in the art to prepare Chinese medicine composition of the present invention.
In case of necessity, also comprise pharmaceutically acceptable carrier in the present composition, the consumption of described pharmaceutically acceptable carrier, kind are determined according to physicochemical property and the factors such as content, preparation type of effective ingredient in Chinese medicine composition.
Pharmaceutically acceptable carrier of the present invention is the conventional excipients for the preparation of above-mentioned preparation well known in the art or adjuvant.The excipient that oral formulations or external preparation are commonly used or adjuvant include but are not limited to filler (diluent), lubricant (fluidizer or antitack agent), dispersant, wetting agent, binding agent, regulator, solubilizing agent, antioxidant, antibacterial, emulsifying agent etc.Wherein, binding agent, for example syrup, arabic gum, gelatin, sorbitol, tragacanth, cellulose or derivatives thereof, gelatine size, starch slurry or polyvinylpyrrolidone, the preferred cellulose derivant is selected from any of microcrystalline Cellulose, sodium carboxymethyl cellulose, ethyl cellulose or hydroxypropyl methylcellulose, and the preferred starch derivant is selected from any or its combination of carboxymethyl starch sodium, Explotab, pregelatinized Starch, modified starch, hydroxypropyl starch, corn starch; Filler, such as lactose, Icing Sugar, dextrin, starch or derivatives thereof, cellulose or derivatives thereof, inorganic calcium salt, sorbitol or glycine etc., preferably inorganic calcium salt is selected from calcium sulfate, calcium phosphate, calcium hydrogen phosphate, precipitated calcium carbonate, the preferred cellulose derivant is selected from any of microcrystalline Cellulose, sodium carboxymethyl cellulose, ethyl cellulose or hydroxypropyl methylcellulose, and the preferred starch derivant is selected from any or its combination of carboxymethyl starch sodium, Explotab, pregelatinized Starch, modified starch, hydroxypropyl starch, corn starch; Lubricant, such as micropowder silica gel, magnesium stearate, Pulvis Talci, aluminium hydroxide, boric acid, hydrogenated vegetable oil, Polyethylene Glycol etc.; Disintegrating agent, for example starch or derivatives thereof, polyvinylpyrrolidone or microcrystalline Cellulose, the preferred starch derivant is selected from any or its combination of carboxymethyl starch sodium, Explotab, pregelatinized Starch, modified starch, hydroxypropyl starch, corn starch; Wetting agent, such as sodium lauryl sulphate, water or alcohol etc.; Antioxidant, such as sodium sulfite, sodium sulfite, sodium pyrosulfite, dibutyl benzoic acid etc.; Press down the mattress agent, such as 0.5% phenol, 0.3% cresol, 0.5% chlorobutanol etc.; Acid-base modifier, such as hydrochloric acid, citric acid, potassium hydroxide (sodium), sodium citrate, sodium dihydrogen phosphate, sodium hydrogen phosphate etc.; Emulsifying agent, for example Tween-80, do not have that sour Pyrusussuriensis is smooth, pluronic gram F-68, lecithin, fabaceous lecithin etc.; Solubilizing agent, such as tween 80, bile, glycerol etc.
The Pseudobulbus Bletillae (Rhizoma Bletillae) in Chinese medicine composition of the present invention claims again Pseudobulbus Bletillae (Rhizoma Bletillae), Bletilla striata (Thunb.ex A.Murray)Rchb.f., Pseudobulbus Bletillae (Rhizoma Bletillae), Cold boiled chicken, Cold boiled chicken baby, Lian Jicao, YANGJIAOQI, sweet, pleionebulbocodioides rolfe, white black youngster's head, monarch's ball, is the dry tuber of orchid Pseudobulbus Bletillae (Rhizoma Bletillae) [Bletilla striata (Thunb.) Reichb.f.].Property is bitter, sweet, puckery, is slightly cold.Return lung, liver, stomach warp.There is tonifying the lung, hemostasis, detumescence, granulation promoting, the effects such as sore, hinder hemoptysis for lung, epistaxis, incised wound is hemorrhage, swollen ulcer drug, ulcer pain, the soup fire is burnt, the diseases such as rhagadia manus et pedis.
Herba Patriniae in Chinese medicine composition of the present invention claims again Herba Sonchi Oleracei, Jie Tuolian, little Herba Lactucae versicoloris dish, Herba Ixeritis chinensis, Herba Patriniae, Ixeris denticulata, ground squirrel grass, little Herba Lactucae versicoloris, HUOXUECAO, falls into XUEDAN, little gutweed, Herba Lactucae formosanae dish, Herba Ixeritis Sonchifoliae, light leaf Herba Ixeritis Denticulatae, swallow clothing, Herba Ixeritis chinensis.Nature and flavor are hot, bitter, are slightly cold.Return liver, stomach, large intestine channel.There is heat-clearing and toxic substances removing, removing heat from blood, eliminating carbuncle evacuation of pus, the effects such as stasis-dispelling and pain-killing.For acute appendicitis, the high heat of lung abscess, cough vomiting bloody pus, pyretic toxicity skin ulcer furuncle, and furuncle is bitterly swollen, breast abdomen pain, appendicitis, enteritis, dysentery, puerperal abdonimal pain, the diseases such as dysmenorrhea.
Flos Lonicerae in Chinese medicine composition of the present invention claims again Radix Ophiopogonis, Caulis Lonicerae, silvernine, two color flower rattans, two precious rattans, right-hand rotation rattan, sub-Radix seu Caulis fici Martinii, Aicis galericulata rattan, the dry flower of caprifoliaceae plant Radix Ophiopogonis (Lonicera japonica Thunb) for multiselect.All there is distribution in China Three Eastern Provinces, Guangdong, Hainan, Shandong, the Himalayas, are the good medicine of heat-clearing and toxic substances removing.The sweet cold fragrance of property, clearing away heat with drugs sweet in flavor and cold in nature and not injuring one's stomach, fragrance thoroughly reaches and can be eliminating evil.Can dispelling wind-heat, kind removing summer-heat blood poison also, for epidemic febrile disease heating, toxic-heat and blood stasis, carbuncle furuncle, sore throat and multi-infection disease, as fever of the body, dermexanthesis, send out the diseases such as speckle, laryngopharynx swelling and pain, and effect is remarkable.
Herba Cirsii in Chinese medicine composition of the present invention claims again wild Flos Carthami, spinule lid, thorn dish, cat Ji, blue or green field thistle, thousand needle grass, field thistle dish, field thistle (Cirsium setosum), blue and green dish, luxuriant dish, rifle cutter dish, wild Flos Carthami, Cai,Ci angle, thorn angle bud, wood thorn Chinese mugwort, thorn stick dish, thorn spinoblast, thorn herbicide, shepherd's purse shepherd's purse hair, little evil hen, Ci Luobu, Herba Cirsii nurse, oriental dodartia herb, cattle to jab, sting tip grass, thorn tooth dish (the northern call in Henan Province).Plant for the Compositae Cirsium.Be distributed in the most of China area, Central Europe, Eastern Europe, Russian east, Japan, Korea etc.The property sweet, bitter, cold.GUIXIN, Liver Channel.Have cooling blood for hemostasis, the effects such as removing blood stasis to reduce swelling, for epistaxis, spit blood, and hematuria, have blood in stool, metrostaxis, traumatic hemorrhage, the diseases such as carbuncle sore tumefacting virus.
Flos Carthami in Chinese medicine composition of the present invention claims again shuteria pampaniniana, thorn Flos Carthami, Flos Carthami, golden red flower.The ground such as main product Henan, Zhejiang, Sichuan.The property suffering, temperature.GUIXIN, Liver Channel.Tubular corolla for feverfew Flos Carthami (Carthamus tinctorius L.).The fragrant row of gas is loose, enters blood system and has promoting blood circulation to restore menstrual flow, the effect of stasis-dispelling and pain-killing.For dysmenorrhea, amenorrhea, lochia, lump in the abdomen mass in the abdomen, puerperal blood faints, the stagnant stomachache of the stasis of blood, obstruction of qi in the chest and cardialgia, accumulation of blood, traumatic injury congestive edema, arthralgia, paralysis due to windstroke, the diseases such as macular eruption being dark-purple.
Flos Sophorae nature and flavor in Chinese medicine composition of the present invention are bitter, be slightly cold, and return liver, lung, the heart, large intestine channel; Enter blood and hold back and fall, body is slightly loose; There is cooling blood for hemostasis, the effects such as liver heat removing and eyesight improving pathogenic fire purging.For discharging fresh blood stool, hemorrhoidal bleeding, dysentery, hematuria, stranguria with blood, metrorrhagia, spit blood, epistaxis, liver-fire headache, conjunctival congestion and swelling pain, sore throat, aphonia, the diseases such as ulcer sores." book on Chinese herbal medicine just " carries: " cool large intestine kills the infantile malnutrition worm.Control skin sore, erosion of vulva pruritus due to damp pathogen, anal fistula, separate the Fructus Myricae rubrae malignant boil, primary sore volt poison." modern medicine study confirms, the contained globulariacitrin of Flos Sophorae can strengthen capillary resistance, improves blood vessel wall fragility, reduces blood pressure, edema, hypertension is had to the effect that prevents rupture of blood vessel in brain, also has antiinflammatory action.Flos Sophorae (is rutin, Rytub), the materials such as Quercetin (Quercetin), tannin, sophoradiol (sophoradiol), vitamin A containing rutin.Wherein, rutin has the blood capillary of improvement function, keep the normal resistance of blood capillary, prevent because of capillary fragility excessive, permeability too high and cause hemorrhage, but prophylaxis of hypertension or diabetics is hemorrhage, and be the treatment common medicine of having blood in stool, the hemorrhoid hemorrhage caused for damp-heat in the large intestine, have blood in stool, haematemesis, epistaxis that dysentery and heat in blood cause.
Radix Sanguisorbae in Chinese medicine composition of the present invention claims again Matteuccia struthiopteri, mountain region melon, pig ginseng, spouting bleeding from anus grass.Be widely distributed in Europe, north temperate zone, Asia, the ground such as China Dark Longjiang, Jilin, Liaoning, the Inner Mongol, Hebei, Shanxi, Shaanxi, Gansu, Qinghai, Xinjiang, Shandong, Henan, Jiangxi, Jiangsu, Zhejiang, Anhui, Hunan, Hubei, Guangxi, Sichuan, Guizhou, Yunnan, Tibet.Cold nature, bitter in the mouth, acid, puckery, nontoxic, enter Liver Channel, lung meridian, kidney channel, large intestine channel, there is cooling blood for hemostasis, heat-clearing and toxic substances removing, the effects such as detumescence sore, cure mainly: have blood in stool, hemorrhoidal bleeding, dysentery, metrorrhagia, burn due to hot liquid or fire, carbuncle sore tumefacting virus swells and ache, and spits blood, spitting of blood, epistaxis, hematuria, leucorrhea with red and white discharge, eczema, pudendal pruritus, snake bite and insect sting etc." not Lu " carries: " pus and blood only, all flaccidity, malignant boil, the wine that disappears, except quenching one's thirst, mend wound absolutely, and in puerperal, plug, can make incised wound cream, and main internal hemorrhage due to trauma is more than, insufficiency of blood.”。The modern medicine study confirmation, Radix Sanguisorbae contains a large amount of tannins, and stronger convergence is arranged, the energy vasoconstrictive, the permeability of reduction blood vessel, reduce inflammatory exudation, also has obvious bactericidal action, the antagonism charrin's disease.
Radix Glycyrrhizae in Chinese medicine composition of the present invention claims again that Glycyrrhizae, close sweet, close grass, state are old, Radix Glycyrrhizae, Herba Hedyotis cantonensis, sweet root, rod grass, be divided into eastern Radix Glycyrrhizae (east grass), western Radix Glycyrrhizae (Radix Rubiae), comprise the outer grass of fine strain of millet, Cao, Xinjiang, Cao, northeast, Cao, northwest, Cao, limit, Cao,Shang rivers and creeks, chieftain's DICAO ,Xi town grass, skin Radix Glycyrrhizae, Radix Glycyrrhizae, Radix Glycyrrhizae etc.Property is put down, and sweet in the mouth, return 12 warps.Select as dicotyledon pulse family (Leguminosae) Radix Glycyrrhizae (Glycyrrhiza uralensis Fisch.) Glycyrrhiza inflata Bat. (G.inflata Bat.), or the root and rhizome of Glycyrrhiza glabra L. (G.glabra L.).There is invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription, spasmolytic, the effect such as anticancer.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity or the disease such as strong.
Herba Taraxaci in Chinese medicine composition of the present invention claims again Pu Gongcao, edible Herba Taraxaci, wet the bed careless, the West Herba Taraxaci, wild duck Herba Taraxaci (" prescriptions worth thousand gold "), sow with a drill straw in a mattress (Tang Materia Medica), Herba Taraxaci (supplement to Thousand Golden Prescriptions) Herba Taraxaci (" Bencao Tujing "), Herba Violae (amplification on Canon of Materia Medica), Herba Taraxaci (" scholar Su Bencao "), comet comet fourth dish, the Hemerocallis citrina Baroni Seedling, Hemerocallis citrina Baroni youth (herbal for Relief of Famines), wood pigeon English (" hot beautiful volume in heptan "), grandmother's fourth (" the southern regions of the Yunnan Province book on Chinese herbal medicine "), white drum fourth (" wild herbs spectrum "), Herba crotalariae albidae, Pu Gongding, true expectorant grass, Canis familiaris L. silkweed (" detailed outline "), milk grass (" herbal classic is met former "), the residual pendant (" the SHENGCAO property of medicine is standby to be wanted ") that flies, yellow dog head (" Zhiwu Mingshi Tukao "), foretell DIWUGONG, bitter palpus, Herba Clerodendri fortunati (" vegetation is side just "), sheep milk Herba Euphorbiae Humifusae (" book on Chinese herbal medicine justice "), two English fore-tellings ground (" expensive > > side's medicine collection among the people "), Herba Malvastri Coromandeliani, Gu Guding (" will is planted in Jiangsu "), thatch Radix Raphani (" Traditional Chinese Medicine in Sichuan will "), Rhizoma Trillii Tschonoskii (" the Hangzhou medicine is planted will "), grandmother's fourth (Liaoning), the public small-mouthed jar (" Bencao Tujing collection ") of falling forward.The property sweet, micro-hardship, cold, enter liver and enter stomach.There is heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, the effects such as inducing diuresis for treating stranguria syndrome.For upper respiratory tract infection, eye conjunctivitis, mumps, hyperglycemia, acute mastitis swells and ache, gastritis, dysentery, hepatitis, gallbladder is assisted inflammation, acute appendicitis, urinary system infection, pelvic inflammatory disease, carbuncle furuncle furuncle, pharyngitis, acute mastitis, lymphadenitis, scrofula, the furuncle carbuncle toxin, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, urinary tract infection, scrofula, jaundice due to damp-heat, the puckery pain of pyretic stranguria, acute mastitis; Lung abscess; The intestinal carbuncle; Mumps; Conjunctival congestion and swelling pain; Cough; Laryngopharynx swelling and pain; Stomach-fire; The diseases such as enteritis." the southern regions of the Yunnan Province book on Chinese herbal medicine " carries: " control all pyogenic infections from tumour or sore, ruined tinea skin ulcer; Dispel the wind, all sores that disappears, loose scrofula tuberculosis; Stop little having blood in stool, control the five types of stranguria difficulty in urination, sharp bladder.”。Clinic study shows, the dandelion preparation has broad-spectrum antibiotic and antiviral effect.
The scale that stir-baked SQUAMA MANITIS in Chinese medicine composition of the present invention is Squama Manis(parched).Property one-tenth, be slightly cold.There is detumescence suppuration, scattered silt dredging collateral, stimulate the menstrual flow, the effects such as stimulating milk secretion, invigorating blood circulation analgesia., anemofrigid-damp arthralgia swollen for the carbuncle skin ulcer, amenorrhea, galactostasis, hemostasis, disease crust such as gather at the disease.
Radix Salviae Miltiorrhizae in Chinese medicine composition of the present invention claims again Radix Salviae Miltiorrhizae, SHANSHEN, Radix Salviae Miltiorrhizae, Arisaema balansae Engl., red warm medicine, purple Radix Codonopsis, Radix Ginseng Rubra, Herba Wedeliae Wallichii, Herba Wedeliae Wallichii root, Panax ginseng, RADIX SALVIAE MILTIORRHIZAE, Radix Salviae Miltiorrhizae, blood is taken root, the blood mountain root, wooden Lac caprae seu ovis, connect horse, the mountain Radix Dauci Sativae, Radix Salviae Miltiorrhizae, the backer is red, liquor kettle root, Pedicularis grandiflora root, the Herba Rabdosiae glaucocalycis root, Radix Campylotropis Hirtella (Herba Myrsines Africanae), honey jar head, Mel tank, a flower root, but Cicadae grass roots, galloping horse grass roots, long Salvia japonica Thunb. root, water Leymus chinensis (Trin.) Tzvel. root, Epicauta gorhami's daughter root.Dry root and rhizome for dicotyledon Labiatae (Labiatae) salvia Radix Salviae Miltiorrhizae (Salvia miltiorrhiza Bge.).The property hardship, be slightly cold.GUIXIN, Liver Channel.There is promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, the removing heat from blood eliminating carbuncle, the effects such as relieving restlessness, nourishing blood to tranquillize the mind clear away heart-fire.For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, the diseases such as angina pectoris.
Radix Angelicae Sinensis in Chinese medicine composition of the present invention claims again that Radix Angelicae Sinensis, cloud are returned, western Radix Angelicae Sinensis, Min Radix Angelicae Sinensis.Warm in nature, sweet, arduous.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effects such as loosening bowel to relieve constipation.For umbelliferae angelica (Angelica sinensis (Oliv.) D) iels) dry root.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores, mass in the abdomen knot, gather; Metrorrhagia; Flaccidity syndrome and arthralgia syndrome; Numbness of the skin; Heavily wait disease after bloody dysentery." book on Chinese herbal medicine is just " carries: " its sweet in the mouth and weigh, therefore specially can enrich blood, its gas is light and hot, thus again can promoting the circulation of blood, can support nutrition blood, QI invigorating spermatogenesis, settling five organs, body by force, beneficial mind.”。Modern medicine study confirms, antibiotic, antiinflammation that Radix Angelicae Sinensis has.
Cortex Moutan in Chinese medicine composition of the present invention claims again moutan root bark, Cortex Moutan, DANGEN.Main product Hunan, Hubei, Anhui, Sichuan, Gansu, Shaanxi, Shandong, Guizhou, Yunnan, zhejiang and other places.Cold in nature, bitter, cool.GUIXIN, liver, kidney, lung meridian.There is the effects such as clearing away heat and cooling blood, promoting blood circulation to remove blood stasis.For amenorrhea due to stagnation of blood; Dysmenorrhea; Carbuncle sore tumefacting virus; Fall and flutter the pain of injury; The diseases such as rheumatism pyretic arthralgia.
Sanguis Draxonis in Chinese medicine composition of the present invention claims again that black horse Lin exhausts, sea wax, dragon's blood, wooden Sanguis Draxonis.Resin in babassu Sanguis Draxonis fruit and rattan.The property sweet one-tenth, flat.Promoting blood circulation to remove blood stasis for oral administration, analgesic therapy, external hemostasia and promoting granulation, sore.For congestion amenorrhea, dysmenorrhea, postpartum stagnation, lump in the abdomen mass in the abdomen, breast ventral spine pain, traumatic injury, congestion swells and ache, traumatic hemorrhage, the diseases such as ulcer being unable to heal.
The dry bulb that Bulbus Fritillariae Cirrhosae in Chinese medicine composition of the present invention is liliaceous plant Bulbus Fritillariae Cirrhosae, dark violet Bulbus Fritillariae Uninbracteatae, Gansu Bulbus Fritillariae Uninbracteatae, Bulbus Fritillariae cirrhosae.First three kind is practised respectively and is called " loose shellfish " and " blue or green shellfish " by the character difference, and the latter practises title " lubei ".Cool in nature, sweet flat.Enter lung meridian, stomach warp.There is the effects such as nourishing the lung to arrest cough, resolving phlegm and relieving asthma, removing heat-phlegm.
Radix Rehmanniae in Chinese medicine composition of the present invention claims again that ground marrow (" herbal classic "), Proterozoic (" book on Chinese herbal medicine justice "), dry Radix Rehmanniae (" Chinese medicinal herbal "), benzyl (" elegant "), glutinous rehmannia (" not record "), Fructus Elaeagni Umbellatae (amplification on Canon of Materia Medica), grandmother's milk (herbal for Relief of Famines), Canis familiaris L. milk (" Zhiwu Mingshi Tukao "), mountain cigarette, Chinese cabbage, wine pot are colored, sweet wine, honey jar.Property sweetness and bitterness, cool.There is heat clearing away, the YIN nourishing of promoting the production of body fluid, the effect such as nourish blood.For fever due to yin deficiency, quench one's thirst, spit blood, epistaxis, metrorrhagia, menoxenia, frequent fetal movement, the moon is hindered the diseases such as constipation.
Radix Paeoniae Rubra in Chinese medicine composition of the present invention claims again wooden Radix Paeoniae (Cui leopard " annotating at all times "), red Radix Paeoniae (" Shengji Zonglu "), Radix Paeoniae Rubra (" medicine justice "), Radix clerodendri bungei (" Qinghai medical material ").Nature and flavor are bitter, be slightly cold.Return Liver Channel.There is the effects such as clearing away heat and cooling blood, eliminating stasis to stop pain.For maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, lump in the abdomen stomachache, injury from falling down, the diseases such as carbuncle skin infection.
Herba Agrimoniae in Chinese medicine composition of the present invention claims again Western Agrimony (" pseudo-medicated strip is distinguished "), Agrimony, execute state Agrimony (" Bencao Tujing "), melon Rhizoma et radix valerianae (herbal for Relief of Famines), HUANGLONG tail (" the southern regions of the Yunnan Province book on Chinese herbal medicine "), ferrum wasp, goldentop dragon bud (" BAICAO mirror "), old stork mouth, the primary and secondary grass, dry foot mattress (" Zhiwu Mingshi Tukao "), the HUANGLONG bud, the imperial bud of grass, Herba Thymi, Herba Malvastri Coromandeliani, Serpentis pimple (Heng Lishi " Chinese Plants register "), the tap grass, very little eight joints (" classification medical herbs "), Lysimachia christinae Hance, dry foot chicken (" Tian Bao book on Chinese herbal medicine "), the Jerry flower, line MAZIHUA (" plant name remittance "), Herba silenes fortunei (" the southern regions of the Yunnan Province book on Chinese herbal medicine collection of illustrative plates "), edge of a knife grass, Herba Blumeae Balsamiferae (" Guizhou side's medicine among the people collection "), ground Herba mesonae chinensis (" the northeast medicine is planted will "), Herba Lespedezae Cuneatae (" the southern regions of the Yunnan Province book on Chinese herbal medicine " arranges this), roadside chicken, radix euphorbiae, chicken feet sand, LUBIANHUANG, five hoof wind, ox head grass (" Hunan medicine will "), the dysentery grass, Folium seu radix sidae mysorensis, different wind neck grass (" east, Fujian medical herbs "), son is not from mother, father and son's grass, hair chicken grass (" Jiangxi traditional herbal medicine proved recipe "), the group orchid grass (Shandong) that relieves internal heat, Herba Agrimoniae grass (Liaoning).The property bitter, puckery, flat.Return lung, liver, spleen, heart channel.There is astringing to arrest bleeding, dysentery relieving, the effects such as parasite killing.For haematemesis, hematuria, have blood in stool, metrorrhagia, spitting of blood, epistaxis, dysentery, impairment caused by overstrain takes off power, carbuncle, traumatic injury, the diseases such as wound hemorrhage, bleeding not during menses." BAICAO mirror " carries: " therapeutic method to keep the adverse QI flowing downwards is invigorated blood circulation, reason all kinds of diseases and ailments, loose feeling of fullness; Fall and flutter haematemesis, metrorrhagia, dysentery, discharging fresh blood stool." modern medicine study confirms, Herba Agrimoniae is the epistasis astringent hemostatic, suppresses the activity of plasmin, heart tonifying is arranged, rises blood pressure, blood coagulation, hemostasis, removing heat from blood, the effect such as antibiotic.
Radix Isatidis in Chinese medicine composition of the present invention claims again indigo root, Isatis indigotica Fort (Indigofera tinctoria L, Baphicanthus cusia (nees) Brem. Polygonum tinctorium Ait) root, Isatis indigotica Fort., careless Folium Isatidis.The property hardship, cold.GUIXIN, stomach warp.There is heat-clearing and toxic substances removing, the effects such as removing heat from blood sore-throat relieving.For maculae caused by violent heat pathogen, crimson tongue is purple dark, mumps, sore throat, scarlet fever, major part pestilence, erysipelas, the diseases such as carbuncle.
Radix Rhapontici root hardship in Chinese medicine composition of the present invention, cold.Return the stomach warp.There is heat-clearing and toxic substances removing, eliminating carbuncle, stimulating milk secretion, the relaxing muscles and tendons effect such as promote blood circulation.For acute mastitis, swell and ache, carbuncle carbuncle on the back, scrofula sore, galactostasis, the diseases such as arthralgia chiefly caused by damp pathogen contracture.
Herba Ecliptae in Chinese medicine composition of the present invention claims again Herba Ecliptae.Aerial parts for catananche's Eclipta prostrata.The property sweet, sour, cold.Return liver, kidney channel.There is the effects such as liver and kidney tonifying, cooling blood for hemostasis., early whitening of beard and hair loosening for the teeth of the hepatic and renal YIN deficiency, vertigo and tinnitus, soreness of the waist and knees, and the haematemesis of YinXuXueRe, epistaxis, hematuria, have blood in stool, metrostaxis, the diseases such as traumatic hemorrhage.
Semen Cassiae in Chinese medicine composition of the present invention claims again Semen Cassiae, the Horse hoof Semen Cassiae, and false Semen phaseoli radiati, go back gb 1.The property sweet, bitter, become, be slightly cold.Return liver, large intestine channel.There is clearing away heat to improve acuity of vision, the effects such as loosening bowel to relieve constipation.For the puckery pain of conjunctival congestion, the many tear of photophobia, the diseases such as dizzy, poor vision, constipation of having a headache.
HERBA SHUTERIAE in Chinese medicine composition of the present invention claims again Caulis Sargentodoxae [Chengdu, Sichuan], Hemerocallis citrina Baroni horsebean, Shuteria pampaniniana Hand.-Mazz., HUDIECAO, boundary Serpentis to lead to.Herb for pulse family Shuteria vegetable hair place bud bean (Shuteria pampaniniana Hand.-Mazz.).Xia Qiu gathers, and clean cutting is dried.The property hardship, cold, cool.Return liver, large intestine channel, there is heat-clearing and toxic substances removing, the effects such as detumescence, for appendicitis, mastitis, parotitis, the diseases such as hemoptysis of pulmonary tuberculosis.
The prescription of Chinese medicine composition of the present invention is rationally unique, there is removing damp-heat, loosening bowel to relieve constipation, dispersing swelling and dissipating binds, detoxifying and relieving itching, the pathogenic fire purging softening the hard mass, eliminating stasis to stop pain, bowel relieving is by hemorrhoid, the sore hemostasis, treat the hemorrhoid blood stasis dispelling, the effects such as removing heat from blood expels the heat-evil, characteristics with treating both the principal and secondary aspects of a disease, significantly improve the local blood circulation of hemorrhoid patients, make its blood cool and without staying the fraud of the stasis of blood, blood is lived and not absurd row, the heat of lung gastrointestinal clears away heart-fire, blood circulation promoting, the acceleration Inflammatory substances absorbs, obviously alleviate and alleviate various hemorrhoid and (comprise internal hemorrhoid, external hemorrhoid, mixed hemorrhoid) clinical symptoms, the disappearance of short its pain and the symptom of having blood in stool, free movement of the bowels, can be used for preventing and treating various hemorrhoid and (comprise internal hemorrhoid, external hemorrhoid or mixed hemorrhoid), acute stage hemorrhoid (inflammatory external hemorrhoid, thrombosed external hemorrhoid, incarcerated hemorrhoid) disease such as hemorrhage pain and after hemorrhoidectomy.
In the present invention, the daily dosage of compositions can be determined according to factors such as patient's the state of an illness, the course of disease, medicining condition, age, sex, body constitution, health status.
The various ways such as Chinese medicine composition of the present invention has the advantages such as safety non-toxic is efficient, and that the patient can adopt is oral, smoke, wash, apply carry out the Comprehensive Treatment of hemorrhoid, significantly improve the cure rate of hemorrhoid, reduce relapse rate, shorten treatment cycle.
The oral dose of Chinese medicine composition of the present invention is 10g/ time, and three times on the one 10 days is a course for the treatment of.
The topical dose of Chinese medicine composition of the present invention is 10g/ time, once-a-day, with boiled water, brews, and the medicine for external use treatment is carried out in any or its combination of select demibain, smoke, wash, applying, and each 15 minutes 10 days is a course for the treatment of.
Another object of the present invention is to be provided for treating the preparation method of hemorrhoid Chinese medicine composition, it is characterized in that, raw material composition and the parts by weight thereof of making described Chinese medicine composition effective ingredient are: Pseudobulbus Bletillae (Rhizoma Bletillae) 10-20 part, Herba Patriniae 5-15 part, Flos Lonicerae 10-20 part, little Thistle 10-20 part, Flos Carthami 10-20 part, Flos Sophorae 10-20 part, Radix Sanguisorbae 10-20 part, Radix Glycyrrhizae 5-15 part, Herba Taraxaci 2-10 part, stir-baked SQUAMA MANITIS 2-10 part, Radix Salviae Miltiorrhizae 5-15 part, Radix Angelicae Sinensis 5-15 part, Cortex Moutan 10-20 part, Sanguis Draxonis 5-15 part, Bulbus Fritillariae Cirrhosae 5-15 part, Radix Rehmanniae 5-15 part, Radix Paeoniae Rubra 5-15 part, Herba Agrimoniae 10-20 part, Radix Isatidis 10-20 part, Radix Rhapontici root 10-20 part, Herba Ecliptae 10-20 part, Semen Cassiae 10-20 part, HERBA SHUTERIAE 10-20 part, comprise the steps:
1) take the Chinese crude drug of described weight portion, it is ground into to coarse powder, add the ethanol water that concentration is 50-80%, reflux, extract, 1-3 hour, filter, and collects extracting solution, wherein, the 8-10 that the addition of ethanol water is the medical material total amount is (envelope-bulk to weight ratio) doubly; Perhaps
Add medical material total amount 4-6 50-80% ethanol water (envelope-bulk to weight ratio) doubly in extracting medicinal residues, reflux, extract, 1-3 hour, filter, and collects merge extractive liquid;
2) by step 1) standing 12～36 hours of the extracting solution collected, filter, get supernatant;
3) by step 2) supernatant concentration to the relative density of collecting is 1.00～1.35 (40 ℃ of mensuration), dry, pulverize, obtain.
In the preferred technical solution of the present invention, raw material composition and the parts by weight thereof of making described Chinese medicine composition effective ingredient are: Pseudobulbus Bletillae (Rhizoma Bletillae) 12-18 part, Herba Patriniae 8-12 part, Flos Lonicerae 12-18 part, little Thistle 12-18 part, Flos Carthami 12-18 part, Flos Sophorae 12-18 part, Radix Sanguisorbae 12-18 part, Radix Glycyrrhizae 8-12 part, Herba Taraxaci 4-8 part, stir-baked SQUAMA MANITIS 4-8 part, Radix Salviae Miltiorrhizae 8-12 part, Radix Angelicae Sinensis 8-12 part, Cortex Moutan 12-18 part, Sanguis Draxonis 8-12 part, Bulbus Fritillariae Cirrhosae 8-12 part, Radix Rehmanniae 8-12 part, Radix Paeoniae Rubra 8-12 part, Herba Agrimoniae 12-18 part, Radix Isatidis 12-18 part, Radix Rhapontici root 12-18 part, Herba Ecliptae 12-18 part, Semen Cassiae 12-18 part, HERBA SHUTERIAE 12-18 part.
In the preferred technical solution of the present invention, raw material composition and the parts by weight thereof of making described Chinese medicine composition effective ingredient are: 15 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 10 parts of Herba Patriniae, 15 parts of 15 parts of ， little Thistle of Flos Lonicerae, 15 parts, Flos Carthami, 15 parts, Flos Sophorae, 15 parts of Radix Sanguisorbaes, 10 parts, Radix Glycyrrhizae, 5 parts of Herba Taraxacis, 5 parts of stir-baked SQUAMA MANITISs, 10 parts of Radix Salviae Miltiorrhizaes, 10 parts of Radix Angelicae Sinensis, 15 parts of Cortex Moutans, 10 parts of Sanguis Draxonis, 10 parts of Bulbus Fritillariae Cirrhosaes, 10 parts of Radix Rehmanniae, 10 parts of Radix Paeoniae Rubra, 15 parts of Herba Agrimoniaes, 15 parts of Radix Isatidis, 15 parts of Radix Rhapontici roots, 15 parts of Herba Ecliptaes, 15 parts of Semen Cassiaes, 15 parts of HERBA SHUTERIAEs.
In the preferred technical solution of the present invention, the concentration of ethanol water is 60-70%.
In the preferred technical solution of the present invention, by step 2) supernatant concentration to the relative density of collecting is 1.15～1.30 (40 ℃ of mensuration).
Another object of the present invention is to provide Chinese medicine composition to be used for the treatment of hemorrhoid, alleviate pain after hemorrhoidectomy, alleviate the application in the medicine of any or its combination of edema after hemorrhoidectomy.
In the preferred technical solution of the present invention, described hemorrhoid are selected from any or its combination of external hemorrhoid, internal hemorrhoid, mixed hemorrhoids.
Except as otherwise noted, while the present invention relates to the percentage ratio between liquid and liquid, described percentage ratio is volume/volume percentage ratio; While the present invention relates to the percentage ratio between liquid and solid, described percentage ratio is volume/weight percentage ratio; While the present invention relates to the percentage ratio between solid and liquid, described percentage ratio is weight/volume percent; All the other are weight/percentage by weight.
Compared with prior art, Chinese medicine composition of the present invention has following useful technique effect:
1, the prescription of Chinese medicine composition of the present invention is rationally unique, there is removing damp-heat, loosening bowel to relieve constipation, dispersing swelling and dissipating binds, detoxifying and relieving itching, the pathogenic fire purging softening the hard mass, eliminating stasis to stop pain, bowel relieving is by hemorrhoid, the sore hemostasis, treat the hemorrhoid blood stasis dispelling, the effects such as removing heat from blood expels the heat-evil, characteristics with treating both the principal and secondary aspects of a disease, significantly improve the local blood circulation of hemorrhoid patients, make its blood cool and without staying the fraud of the stasis of blood, blood is lived and not absurd row, the heat of lung gastrointestinal clears away heart-fire, blood circulation promoting, the acceleration Inflammatory substances absorbs, obviously alleviate and alleviate various hemorrhoid and (comprise internal hemorrhoid, external hemorrhoid, mixed hemorrhoid) clinical symptoms, the disappearance of short its pain and the symptom of having blood in stool, free movement of the bowels, can be used for preventing and treating various hemorrhoid and (comprise internal hemorrhoid, external hemorrhoid or mixed hemorrhoid), acute stage hemorrhoid (inflammatory external hemorrhoid, thrombosed external hemorrhoid, incarcerated hemorrhoid) disease such as hemorrhage pain and after hemorrhoidectomy.
2, Chinese medicine composition of the present invention has determined curative effect (effective percentage 100%), safe, cure rate is high (up to 99.1%), effect duration is long, side effect is little, easy to use, raw material is easy to get, cheap, have no side effect, have no adverse reaction, relapse rate low (relapse rate≤1.1%), short treating period (15-20 days), be convenient to store and the advantages such as transportation.
3, Chinese medicine composition of the present invention is longer to sick time, and it is more outstanding that the patient that the state of an illness is more serious has the disappear merit of heavily fortified point of removing toxic substances, and speed obtains the effect of internal diabetes.
4, with positive control medicine (MAYINGLONG MUSK HEMORRHOID UNGUENTUM, clean ball admittedly) compare, Chinese medicine composition of the present invention is to internal hemorrhoid, external hemorrhoid, mixed hemorrhoid and postoperative pain thereof have better curative effect, and the patient can hold concurrently adopt oral, smoked, wash, apply and wait various ways to carry out Comprehensive Treatment, significantly improved the cure rate of various hemorrhoid, reduce relapse rate, shorten treatment cycle, there is determined curative effect, safe and effective, be difficult for recurrence, treatment cycle is short, using method is simple and easy to do, raw material is easy to get, cheap, having no any has no side effect, obviously alleviate and swell and ache, convergence local vascular and nerve, promote the advantages such as scalpel edge healing, improved widely the compliance of patient's medication, effectively alleviated the misery of hemorrhoid patients, improved the quality of life of hemorrhoid patients, be applicable to internal hemorrhoid fully, external hemorrhoid, the daily nursing of mixed hemorrhoid and postoperative care, be suitable for clinical expansion to use.
The specific embodiment
Illustrate the present invention below with reference to embodiment, embodiments of the invention are only for technical scheme of the present invention is described, and non-limiting essence of the present invention.
embodiment 1the preparation of hemorrhoid treating Chinese medicine composition
Consisting of of the present embodiment Chinese medicine composition:
Pseudobulbus Bletillae (Rhizoma Bletillae) 15g, Herba Patriniae 10g, Flos Lonicerae 15g ， little Thistle 15g, Flos Carthami 15g, Flos Sophorae 15g, Radix Sanguisorbae 15g, Radix Glycyrrhizae 10g, Herba Taraxaci 5g, big gun front three 5g, Radix Salviae Miltiorrhizae 10g, Radix Angelicae Sinensis 10g, Cortex Moutan 15g, Sanguis Draxonis 10g, Bulbus Fritillariae Cirrhosae 10g, Radix Rehmanniae 15g, Radix Paeoniae Rubra 10g, Herba Agrimoniae 15g, Radix Isatidis 15g, Radix Rhapontici root 15g, Herba Ecliptae 15g, Semen Cassiae 15g, HERBA SHUTERIAE 15g.
The preparation method of the present embodiment Chinese medicine composition, comprise the steps:
1) take the Chinese crude drug of described weight portion, it is ground into to coarse powder, add the ethanol water that concentration is 70%, reflux, extract, 2 hours, filter, and collects extracting solution, wherein, and 10 times (envelope-bulk to weight ratios) that the addition of ethanol water is the medical material total amount; Perhaps
70% ethanol water (envelope-bulk to weight ratio) that adds 4 times of medical material total amounts in extracting medicinal residues, reflux, extract, 1 hour, filter, and collects merge extractive liquid;
2) by step 1) standing 26 hours of the extracting solution collected, filter, get supernatant;
3) by step 2) supernatant concentration to the relative density of collecting is 1.20 (40 ℃ of mensuration), dry, pulverize, obtain.
embodiment 2the preparation of hemorrhoid treating Chinese medicine composition
Consisting of of the present embodiment Chinese medicine composition:
Pseudobulbus Bletillae (Rhizoma Bletillae) 20g, Herba Patriniae 12g, Flos Lonicerae 18g ， little Thistle 20g, Flos Carthami 18g, Flos Sophorae 20g, Radix Sanguisorbae 18g, Radix Glycyrrhizae 15g, Herba Taraxaci 8g, big gun front three 6g, Radix Salviae Miltiorrhizae 15g, Radix Angelicae Sinensis 15g, Cortex Moutan 20g, Sanguis Draxonis 15g, Bulbus Fritillariae Cirrhosae 15g, Radix Rehmanniae 18g, Radix Paeoniae Rubra 12g, Herba Agrimoniae 18g, Radix Isatidis 20g, Radix Rhapontici root 20g, Herba Ecliptae 18g, Semen Cassiae 16g, HERBA SHUTERIAE 20g.
The preparation method of the present embodiment Chinese medicine composition is with embodiment 1.
test example 1the effectiveness study of Chinese medicine composition hemorrhoid of the present invention
1. clinical data
300 routine hemorrhoid patients are divided at random to 1 group for the treatment of (Chinese medicine composition that the oral and external embodiment of the present invention 1 makes simultaneously), treat 2 groups (Chinese medicine compositions that the oral and external embodiment of the present invention 2 makes simultaneously), contrast 1 group (external MAYINGLONG MUSK HEMORRHOID UNGUENTUM) and 2 groups of contrasts (oral clean ball 20 balls admittedly every day), wherein, treat 1 group of 110 example and (comprise internal hemorrhoid 40 examples, external hemorrhoid 35 examples, mixed hemorrhoid 35 examples), comprise male 55 examples, female's 55 examples; Treat 2 group of 110 example (comprising internal hemorrhoid 35 examples, external hemorrhoid 36 examples, mixed hemorrhoid 39 examples), comprise male 45 examples, female's 65 examples; Contrast 1 group of 40 example (comprising internal hemorrhoid 7 examples, external hemorrhoid 16 examples, mixed hemorrhoid 17 examples), comprise male 25 examples, female's 15 examples; Contrast 2 group of 40 example (comprising internal hemorrhoid 20 examples, external hemorrhoid 10 examples, mixed hemorrhoid 10 examples), comprise male 20 examples, female's 20 examples.Four groups of no difference of science of statistics, have comparability.
2. diagnostic criteria
Internal hemorrhoid: dyschesia, the falling inflation sense is arranged, having a rest property of defecation time band blood, to bleed or spray blood, blood stasis is deviate from.
External hemorrhoid: anus edge skin fold projection, red and swollen heat pain, edema, obviously congested, have tenderness, and during defecation, pain increases the weight of, and a small amount of secretions is arranged, and what have can be with general malaise and heating.
Mixed hemorrhoid: have the mixed hemorrhoids double characteristic concurrently, clinically take mucous membrane of rectum and skin is deviate from, falling inflation, pain, repeated infection are cardinal symptom, and the internal hemorrhoid growth site often is connected with external hemorrhoid.
3. Therapeutic Method
1) treat 1 group: patient's Chinese medicine composition that the oral and external embodiment of the present invention 1 makes simultaneously, wherein, oral administration dosage is 10g/ time, three times on the one 10 days is a course for the treatment of; Topical dose is 10g/ time, once-a-day, any or its compound mode that brews demibain, smokes, washes, applies with boiled water all can, each 15 minutes 10 days is a course for the treatment of.
2) treat 2 groups: patient's Chinese medicine composition that the oral and external embodiment of the present invention 2 makes simultaneously, wherein, oral administration dosage is 10g/ time, three times on the one 10 days is a course for the treatment of; Topical dose is 10g/ time, once-a-day, any or its compound mode that brews demibain, smokes, washes, applies with boiled water all can, each 15 minutes 10 days is a course for the treatment of.
3) contrast 1 group: patient's by specification is used (external) MAYINGLONG MUSK HEMORRHOID UNGUENTUM, within 10 days, is a course for the treatment of.
4) contrast 2 groups: the patient 10 days is a course for the treatment of on an empty stomach with oral clean ball 20 balls admittedly of rice water every day.
Viewing duration all medicines of stopping using, look steadily the patient and be careful in one's diet, and keeps free movement of the bowels, avoids pungent.Treat statistical result after 2 courses for the treatment of.
4. efficacy assessment standard
" traditional Chinese medical science anorectal section Illnesses Diagnoses criterion of therapeutical effect " of with reference to State Administration of Traditional Chinese Medicine, promulgating determines efficacy assessment standard.
1) cure: without symptoms such as having blood in stool, deviate from, blood stasis disappears or atrophy fully;
2) produce effects: without the symptom such as having blood in stool, deviate from, blood stasis dwindles or atrophy is original 1/3;
3) effective: have after an action of the bowels and have blood in stool on a small quantity or even having blood in stool, companion's blood stasis is slightly deviate from, and blood stasis dwindles or atrophy is original 2/3;
4) invalid: sings and symptoms is without improving or increasing the weight of.
The results are shown in Table 1.
The curative effect of table 1 traditional Chinese medicine composition for treating hemorrhoid of the present invention
| The disease example | Case load | Cure % | Produce effects % | Effective % | Invalid % |
| Treat 1 group | 110 (men 55, the female 55) | 99.81％ | 100％ | 100％ | Nothing |
| Treat 2 groups | 110 (men 45, the female 65) | 99.81％ | 100％ | 100％ | Nothing |
| Contrast 1 group | 40 (men 25, the female 15) | 85％ | 92％ | 96.7％ | 3.3％ |
| Contrast 2 groups | 40 (men 20, the female 20) | 75％ | 90％ | 95.3％ | 4.7％ |
| Add up to | 300 | ? | ? | ? | ? |
From table 1,118 example recoveries from illness are arranged in the routine patient for the treatment of group 220, cure rate is 99.1%.Chinese medicine composition of the present invention has following characteristics:
1) prescription is rationally unique, there is removing damp-heat, loosening bowel to relieve constipation, dispersing swelling and dissipating binds, detoxifying and relieving itching, the pathogenic fire purging softening the hard mass, eliminating stasis to stop pain, bowel relieving is by hemorrhoid, the sore hemostasis, treat the hemorrhoid blood stasis dispelling, the effects such as removing heat from blood expels the heat-evil, characteristics with treating both the principal and secondary aspects of a disease, significantly improve the local blood circulation of hemorrhoid patients, make its blood cool and without staying the fraud of the stasis of blood, blood is lived and not absurd row, the heat of lung gastrointestinal clears away heart-fire, blood circulation promoting, the acceleration Inflammatory substances absorbs, obviously alleviate and alleviate various hemorrhoid and (comprise internal hemorrhoid, external hemorrhoid, mixed hemorrhoid) clinical symptoms, the disappearance of short its pain and the symptom of having blood in stool, free movement of the bowels, can be used for preventing and treating various hemorrhoid and (comprise internal hemorrhoid, external hemorrhoid or mixed hemorrhoid), acute stage hemorrhoid (inflammatory external hemorrhoid, thrombosed external hemorrhoid, incarcerated hemorrhoid) disease such as hemorrhage pain and after hemorrhoidectomy.
2) determined curative effect (effective percentage 100%), safe, cure rate is high (up to 99.1%), effect duration is long, side effect is little, easy to use, raw material is easy to get, cheap, have no side effect, have no adverse reaction, relapse rate low (relapse rate≤1.1%), short treating period (15-20 days), be convenient to store and the advantages such as transportation.
3) longer to sick time, it is more outstanding that the patient that the state of an illness is more serious has the disappear merit of heavily fortified point of removing toxic substances, and speed obtains the effect of internal diabetes.
4) with positive control medicine (MAYINGLONG MUSK HEMORRHOID UNGUENTUM, clean ball admittedly) compare, Chinese medicine composition of the present invention is to internal hemorrhoid, external hemorrhoid, mixed hemorrhoid and postoperative pain thereof have better curative effect, and the patient can hold concurrently adopt oral, smoked, wash, apply and wait various ways to carry out Comprehensive Treatment, significantly improved the cure rate of various hemorrhoid, reduce relapse rate, shorten treatment cycle, there is determined curative effect, safe and effective, be difficult for recurrence, treatment cycle is short, using method is simple and easy to do, raw material is easy to get, cheap, having no any has no side effect, obviously alleviate and swell and ache, convergence local vascular and nerve, promote the advantages such as scalpel edge healing, improved widely the compliance of patient's medication, effectively alleviated the misery of hemorrhoid patients, improved the quality of life of hemorrhoid patients, be applicable to internal hemorrhoid fully, external hemorrhoid, the daily nursing of mixed hemorrhoid and postoperative care, be suitable for clinical expansion to use.
Claims (9)
1. a Chinese medicine composition that is used for the treatment of hemorrhoid, raw material composition and the parts by weight thereof of making described Chinese medicine composition effective ingredient are: Pseudobulbus Bletillae (Rhizoma Bletillae) 10-20 part, Herba Patriniae 5-15 part, Flos Lonicerae 10-20 part, little Thistle 10-20 part, Flos Carthami 10-20 part, Flos Sophorae 10-20 part, Radix Sanguisorbae 10-20 part, Radix Glycyrrhizae 5-15 part, Herba Taraxaci 2-10 part, stir-baked SQUAMA MANITIS 2-10 part, Radix Salviae Miltiorrhizae 5-15 part, Radix Angelicae Sinensis 5-15 part, Cortex Moutan 10-20 part, Sanguis Draxonis 5-15 part, Bulbus Fritillariae Cirrhosae 5-15 part, Radix Rehmanniae 5-15 part, Radix Paeoniae Rubra 5-15 part, Herba Agrimoniae 10-20 part, Radix Isatidis 10-20 part, Radix Rhapontici root 10-20 part, Herba Ecliptae 10-20 part, Semen Cassiae 10-20 part, HERBA SHUTERIAE 10-20 part.
2. Chinese medicine composition according to claim 1, raw material composition and the parts by weight thereof of making described Chinese medicine composition effective ingredient are: Pseudobulbus Bletillae (Rhizoma Bletillae) 12-18 part, Herba Patriniae 8-12 part, Flos Lonicerae 12-18 part, little Thistle 12-18 part, Flos Carthami 12-18 part, Flos Sophorae 12-18 part, Radix Sanguisorbae 12-18 part, Radix Glycyrrhizae 8-12 part, Herba Taraxaci 4-8 part, stir-baked SQUAMA MANITIS 4-8 part, Radix Salviae Miltiorrhizae 8-12 part, Radix Angelicae Sinensis 8-12 part, Cortex Moutan 12-18 part, Sanguis Draxonis 8-12 part, Bulbus Fritillariae Cirrhosae 8-12 part, Radix Rehmanniae 8-12 part, Radix Paeoniae Rubra 8-12 part, Herba Agrimoniae 12-18 part, Radix Isatidis 12-18 part, Radix Rhapontici root 12-18 part, Herba Ecliptae 12-18 part, Semen Cassiae 12-18 part, HERBA SHUTERIAE 12-18 part.
3. Chinese medicine composition according to claim 2, the raw material of making described Chinese medicine composition effective ingredient forms and parts by weight are: 15 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 10 parts of Herba Patriniae, 15 parts of 15 parts of ， little Thistle of Flos Lonicerae, 15 parts, Flos Carthami, 15 parts, Flos Sophorae, 15 parts of Radix Sanguisorbaes, 10 parts, Radix Glycyrrhizae, 5 parts of Herba Taraxacis, 5 parts of stir-baked SQUAMA MANITISs, 10 parts of Radix Salviae Miltiorrhizaes, 10 parts of Radix Angelicae Sinensis, 15 parts of Cortex Moutans, 10 parts of Sanguis Draxonis, 10 parts of Bulbus Fritillariae Cirrhosaes, 10 parts of Radix Rehmanniae, 10 parts of Radix Paeoniae Rubra, 15 parts of Herba Agrimoniaes, 15 parts of Radix Isatidis, 15 parts of Radix Rhapontici roots, 15 parts of Herba Ecliptaes, 15 parts of Semen Cassiaes, 15 parts of HERBA SHUTERIAEs.
4. according to the described Chinese medicine composition of claim 1-3 any one, described Chinese medicine composition is selected from any or its combination of oral formulations, external preparation, preferred described oral formulations is selected from any of oral liquid, tablet, capsule, granule, pill, powder, syrup, mixture, spray, distillate medicinal water, medicinal tea, and more preferably described external preparation is selected from any of gel, unguentum, liniment, lotion, suppository, liniment, fumigant, emplastrum, solidifying unguentum, ointment.
5. the preparation method of the described treatment hemorrhoid of a claim 1-3 any one Chinese medicine composition, comprise the steps:
1) take the Chinese crude drug of described weight portion, it is ground into to coarse powder, add the ethanol water that concentration is 50-80%, reflux, extract, 1-3 hour, filter, and collects extracting solution, wherein, the 8-10 that the addition of ethanol water is the medical material total amount is (envelope-bulk to weight ratio) doubly; Perhaps
Add medical material total amount 4-6 50-80% ethanol water (envelope-bulk to weight ratio) doubly in extracting medicinal residues, reflux, extract, 1-3 hour, filter, and collects merge extractive liquid;
2) by step 1) standing 12～36 hours of the extracting solution collected, filter, get supernatant;
3) by step 2) supernatant concentration to the relative density of collecting is 1.00～1.35 (40 ℃ of mensuration), dry, pulverize, obtain.
6. preparation method according to claim 5, the concentration of described ethanol water is 60-70%.
7. according to the described preparation method of claim 5-6 any one, by step 2) supernatant concentration to the relative density of collecting is 1.15～1.30 (40 ℃ of mensuration).
8. the Chinese medicine composition that the described Chinese medicine composition of claim 1-4 any one or the described preparation method of claim 5-7 any one make is used for the treatment of hemorrhoid, alleviate pain after hemorrhoidectomy, alleviate the application in the medicine of any or its combination of edema after hemorrhoidectomy.
9. application according to claim 8, described hemorrhoid are selected from any or its combination of external hemorrhoid, internal hemorrhoid, mixed hemorrhoids.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103860938A (en) * | 2014-03-14 | 2014-06-18 | 赵春霞 | Traditional Chinese medicinal composition for treating haemorrhoids and nursing method for haemorrhoids |
| CN105412392A (en) * | 2015-12-07 | 2016-03-23 | 叶宗耀 | Traditional Chinese medicinal composition for treating hemorrhoids and preparation method of traditional Chinese medicinal composition |
| CN106362044A (en) * | 2016-09-29 | 2017-02-01 | 武汉安孕堂生物科技有限公司 | Chinese medicine gel used for treating hemorrhoids of pregnant women |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101816742A (en) * | 2010-06-02 | 2010-09-01 | 泰一和浦（北京）中医药研究院有限公司 | Chinese medicinal composition for treating hemorrhoids and preparation method thereof |
| CN102000175A (en) * | 2010-11-17 | 2011-04-06 | 黄文珍 | Traditional Chinese medicine composition for treating hemorrhoids and preparation method thereof |
| CN103271912A (en) * | 2011-04-29 | 2013-09-04 | 安徽贝克生物制药有限公司 | Pharmaceutical composition with obviously reduced drug resistance and preparation method and application thereof |
-
2013
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101816742A (en) * | 2010-06-02 | 2010-09-01 | 泰一和浦（北京）中医药研究院有限公司 | Chinese medicinal composition for treating hemorrhoids and preparation method thereof |
| CN102000175A (en) * | 2010-11-17 | 2011-04-06 | 黄文珍 | Traditional Chinese medicine composition for treating hemorrhoids and preparation method thereof |
| CN103271912A (en) * | 2011-04-29 | 2013-09-04 | 安徽贝克生物制药有限公司 | Pharmaceutical composition with obviously reduced drug resistance and preparation method and application thereof |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103860938A (en) * | 2014-03-14 | 2014-06-18 | 赵春霞 | Traditional Chinese medicinal composition for treating haemorrhoids and nursing method for haemorrhoids |
| CN105412392A (en) * | 2015-12-07 | 2016-03-23 | 叶宗耀 | Traditional Chinese medicinal composition for treating hemorrhoids and preparation method of traditional Chinese medicinal composition |
| CN106362044A (en) * | 2016-09-29 | 2017-02-01 | 武汉安孕堂生物科技有限公司 | Chinese medicine gel used for treating hemorrhoids of pregnant women |
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Application publication date: 20131225 |