CN105267499A - Medicament for treatment of urethritis and preparation method - Google Patents
Medicament for treatment of urethritis and preparation method Download PDFInfo
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Abstract
The invention discloses a medicament for treatment of urethritis and a preparation method. The medicament is prepared from the following main bulk drugs by weight: 9-15 of cornus officinalis, 10-14 of tibetan hellebore, 8-15 of Bischofia polycarpa leaf, 7-14 of Ipomoea Pescaprae, 11-16 of Herb of Tibet Lancea, 9-14 of caudate sweetleaf leaf, 7-13 of Japanese Honeysuckle Stem, 8-14 of Homalomena occulta, 6-12 of Melastoma sanguineum Sims, 10-14 of ramie leaf, 7-15 of Codonopsis pilosula, 9-13 of Lythrum salicaria, 11-15 of cherry leaf, and 8-13 of Ajuga nipponensis Makino. The medicament provided by the invention is safe and effective, does not produce drug tolerance and drug resistance, can achieve the purpose of radical treatment, and has the characteristics of no side effect, thorough treatment, and no relapse after healing.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of medicament and the method for making of curing urethritis.
Background technology
The inflammation of urethritis and mucous membrane of urethra is the commonly encountered diseases of urinary system, due to the length of female urethra and the position of urethra, makes the protection of women to urinary system have a congenital defect, so common female patient.A lot of patient is after use western medical treatment at present, can not cure thoroughly, and due to side effects of pharmaceutical drugs, easily cause disease recurrent exerbation.
It is due to unclean sexual life that the traditional Chinese medical science recognizes urethritis, or washing implement is unclean, or health preserving is careless, Shi Re Bing Pian invades the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels, injures genitourinary system, then occurs qi and blood stagnation, the syndromes such as spleen-kidney deficiency, so clinically, injure genitourinary system, then occur qi and blood stagnation, the syndromes such as spleen-kidney deficiency, so clinically, primary disease is often divided into damp-heat in lower-JIAO, qi and blood stagnation and the treatment of spleen-kidney deficiency three type.Burnt damp and hot, qi and blood stagnation and the treatment of spleen-kidney deficiency three type.1, lower warmer wetness-heat type.This type is shown in that frequent micturition is short puckery, or the logistics that urethra has yellow-white foul goes out, and women has pudendal pruritus, profuse leukorrhea, lower abdomen pain, and patient is many to glue with bitter taste mouth, the symptoms such as distension and fullness in the abdomen, red tongue with yellowish and greasy fur, stringy and rolling pulse.This is that functioning of bladder is unfavorable because Shi Re Bing Pian invades the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels, can not caused by separating clear and excreting turbid.The suitable clearing away heat-damp and promoting diuresis for the treatment of, detoxifying and descending turbid.Conventional square medicine is as follows: Rhizoma Acori Graminei 20g, Semen Plantaginis 10g, Cortex Phellodendri 10g, Rhizoma Atractylodis Macrocephalae 10g, Radix Salviae Miltiorrhizae 30g, Plumula Nelumbinis 10g, Herba Patriniae 30g, Caulis Lonicerae 30g, Rhizoma Smilacis Glabrae 30g, Radix Glycyrrhizae 10g.2, qi and blood stagnation type.Symptom is common has dribbling urination not smooth, or urethral orifice has foul logistics to go out, or leukorrhagia is abnormal, lower abdominal distention pain, and tongue is dark, and tongue is white, stringy and thready pulse.This is due to pathogen usually intruding into collateral in protracted disease, or due to damp and hot evil obstruction of meridian, caused by qi and blood stagnation.The suitable promoting flow of QI and blood for the treatment of, changes turbid pain relieving.Common drug is Gexia Zhuyu Tang plus-minus: Radix Angelicae Sinensis 10g, Rhizoma Chuanxiong 10g, Radix Paeoniae Rubra 10g, Semen Persicae 10g, Fructus Aurantii Immaturus 10g, Rhizoma Corydalis 10g, Oletum Trogopterori 10g, Radix Linderae 10g, Rhizoma Cyperi 10g, Radix Achyranthis Bidentatae 10g, Rhizoma Smilacis Glabrae 30g, Talcum 20g, Radix Glycyrrhizae 10g.3, deficiency of spleen and stomach type.Cardinal symptom be dribbling urination not to the utmost, meet labor and namely send out, or urethral orifice has the thing of nebulousurine, and women leucorrhea amount is many, soreness of the waist and knees, and large loose stool is thin, pale tongue, and arteries and veins is soft.This loses due to prolonged illness to control wrong treatment, injures spleen kidney.The suitable strengthening spleen, tonifying kidney for the treatment of, removing damp and turbid.Conventional square medicine is that decoction of four noble drugs closes LIUWEI DIHUANG WAN plus-minus: Radix Codonopsis 10g, Radix Astragali 30g, Rhizoma Atractylodis Macrocephalae 10g, Poria 30g, Rhizoma Dioscoreae 30g, Fructus Corni 10g, Radix Rehmanniae Preparata 10g, Rhizoma Alismatis 10g, Cortex Moutan 10g, Radix Achyranthis Bidentatae 10g, Caulis Lonicerae 30g.
Application publication number CN103893437A(application number 201210584305.2) Chinese patent literature disclose a kind of Chinese prescription for the treatment of urethritis, it is made up of the raw material of following weight grams: Rhizoma Coptidis 10-12 gram, Herba Hedyotidis Diffusae 12-14, Herba Portulacae 14-18 gram, Poria 18-20 gram, Radix Sophorae Flavescentis 12-14 gram, Cortex Dictamni 12-14 gram, Herba Dianthi Bi 10-14 gram, Rhizoma Acori Graminei 8-12 gram, Radix Cyathulae 12-15 gram, Caulis Akebiae 12-14 gram, Radix Glycyrrhizae 6-8 gram.Application publication number CN104771662A(application number 201510110765.5) Chinese patent literature disclose a kind of Chinese medicine composition for the treatment of urethritis, the weight portion of its constitutive material is: Radix Rehmanniae 5-10, Herba Dianthi 4-6, Cortex Lycii 6-8, Flos Lonicerae 15-20, Caulis Akebiae 4-5, Rhizoma Smilacis Glabrae 7-9, Fructus Toosendan 4-5, Radix Ephedrae 2-4, Herba Ixeritis polycephalae 1-3, Rhizoma Anemarrhenae 6-8, Radix Platycodonis 5-8, Herba Sarcandrae 4-5, Cortex Phellodendri 8-10, Rhizoma Polygoni Cuspidati 2-4, Herba Violae 6-8, Flos Lonicerae 20-25, Cortex Moutan 8-10, Scorpio 6-8, Radix Scutellariae 3-5, Fructus Gardeniae 2-4, Radix Seu Caulis Mucunae Sempervirentis 1-3, Radix Crataevae Unilocularis 2-4.Application publication number CN104274703A(application number 201410556912.7) Chinese patent literature disclose a kind of Chinese medicine composition for the treatment of urethritis, it is prepared by the raw material of following parts by weight: Spongilla 15 parts, purple stem Herba monochasmatis 16 parts, Herba platantherae minoris 13 parts, wild Corchorus olitorius L. 12 parts, dawrf mallow 15 parts, blue or green 14 parts of straw sandals, Herba Oberoniae iridifoliae 16 parts, Herba Clematidis Huchouensis grass 12 parts, blue 18 parts of Budgerigar, meat root Radix Crepidis elongatae 12 parts, trillium grass 16 parts, Herba Psiloti Nudi 17 parts, adhesion separation grass 15 parts, Philippine Paphiopedilum (Concolor Paphiopedilum) 12 parts, Neolepisorus ovatus (Bedd.) Ching. 11 parts, Boenninghausenia albiflora 15 parts.
At present, the treatment of acute urethritis is adopted more to the method for antibiotic and chemicals use in conjunction.Between chronic phase, if narrow in external orifice of urethra or urethra, dilation of urethra should be made.As herpes simplex infections selects antiviral drugs, as acyclovir.If patient has urinary irritation symptoms, invalid through conventional antibacterial therapy, and except when having complicated factor to exist, mycoplasma, chlamydia or viral infection should be thought of as, can first use tetracycline to treat.Western medicine mainly adopts antibiotic, and the drug resistance that it has and resistance problems, is also to cause the halfway main cause of recurrent exerbation after treatment urethritis.Although utilized the open source literature for the treatment of by Chinese herbs urethritis at present, mostly can only play the object of alleviation, can not cure completely.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide a kind of medicament and the method for making of curing urethritis.The present invention is safe, effective, can not produce drug resistance and Drug resistance, can reach the object of radical cure, have no side effect, thorough treatment, not recur more.
Technical scheme of the present invention is:
Cure a medicament for urethritis, take off the primary raw material medicine stating weight proportion and be prepared from: Fructus Corni 9-15, Radix Chimonanthi praecocis 10-14, Ramulus et Folium Bischofiae Javanicae leaf 8-15, Herba Ipomoeae Pes-Capraes 7-14, Herba Lanceae Tibeticae 11-16, Folium Symplocoris Caudatae 9-14, Caulis Lonicerae 7-13, Rhizoma Homalomenae 8-14, Radix Melastomatis Sanguinei 6-12, ramie leaf 10-14, Radix Codonopsis 7-15, Herba Lythri Salicariae 9-13, Folium Pruni pseudocerasi 11-15, japanese bugle herb grass 8-13.
Cure a medicament for urethritis, preferred scheme is, takes off the primary raw material medicine stating weight proportion and is prepared from: Fructus Corni 11-14, Radix Chimonanthi praecocis 11-13, Ramulus et Folium Bischofiae Javanicae leaf 10-14, Herba Ipomoeae Pes-Capraes 9-12, Herba Lanceae Tibeticae 12-14, Folium Symplocoris Caudatae 10-13, Caulis Lonicerae 9-11, Rhizoma Homalomenae 10-13, Radix Melastomatis Sanguinei 7-11, ramie leaf 11-13, Radix Codonopsis 9-13, Herba Lythri Salicariae 10-12, Folium Pruni pseudocerasi 12-14, japanese bugle herb grass 9-12.
Cure a medicament for urethritis, the scheme be more preferably is, takes off the primary raw material medicine stating weight proportion and is prepared from: Fructus Corni 13, Radix Chimonanthi praecocis 12, Ramulus et Folium Bischofiae Javanicae leaf 12, Herba Ipomoeae Pes-Capraes 11, Herba Lanceae Tibeticae 13, Folium Symplocoris Caudatae 12, Caulis Lonicerae 10, Rhizoma Homalomenae 11, Radix Melastomatis Sanguinei 10, ramie leaf 12, Radix Codonopsis 11, Herba Lythri Salicariae 10.5, Folium Pruni pseudocerasi 13, japanese bugle herb grass 11.
Present invention also offers the preparation method medicament of aforementioned treatment urethritis being made pharmaceutically acceptable powder, granule, tablet and pill.
The preparation method of described powder is:
(1) Ramulus et Folium Bischofiae Javanicae leaf, Folium Symplocoris Caudatae, ramie leaf and Folium Pruni pseudocerasi decoct with water twice, amount of water is the 5.6-6.7 of four taste crude drug gross weights doubly (preferred amount of water is 6.4 times of four taste crude drug gross weights), each decoction 50 minutes, merge twice medicinal liquid, medicinal residues are for subsequent use;
(2) Rhizoma Homalomenae is ground into fine powder, crosses 160-190 mesh sieve (preferred mistake 180 mesh sieve), put into hot pot and fry, little fire stir-fries, stir-fry 20-35 time (preferably per minute stir-fry 30 times) per minute, and stir-fry 2-5 minute (preferably stir-frying 4 minutes), take out, cool, for subsequent use;
(3) all the other the 9 taste crude drug except maple leaf, Folium Symplocoris Caudatae, Rhizoma Homalomenae, ramie leaf and Folium Pruni pseudocerasi are put into pot, add 9 taste crude drug gross weight 6.2-7.2 water (preferably adding the water of 9 taste crude drug gross weight 6.7 times) doubly, decoct 1.2 hours, leach medicinal liquid;
(4) step (1) gained medicinal residues being added step (3) fills in the pot of medicinal residues, add 9 taste crude drug gross weight 5-6 water (preferably adding the water of 9 taste crude drug gross weight 5.4 times) doubly, decoct after 45 minutes, add step (1) gained medicinal liquid, continue decoction 10 minutes, leach medicinal liquid;
(5) step (3) and step (4) gained medicinal liquid merged, be condensed into the thick paste (being preferably condensed into the thick paste that relative density is 1.32) that relative density is 1.3-1.33,65 DEG C of dryings 18 hours, take out, are ground into fine powder, cross 180 mesh sieves;
(6) by step (2) and the mixing of step (5) gained, with 4g often bag subpackage, aseptic subpackaged and get final product.
The preparation method of described granule is:
(1) Ramulus et Folium Bischofiae Javanicae leaf, Folium Symplocoris Caudatae, ramie leaf and Folium Pruni pseudocerasi decoct with water twice, amount of water is the 5.6-6.7 of four taste crude drug gross weights doubly (preferred amount of water is 6.4 times of four taste crude drug gross weights), each decoction 50 minutes, merge twice medicinal liquid, medicinal residues are for subsequent use;
(2) Rhizoma Homalomenae is ground into fine powder, crosses 100-130 mesh sieve (preferred mistake 120 mesh sieve), put into hot pot and fry, little fire stir-fries, stir-fry 20-35 time (preferably per minute stir-fry 30 times) per minute, and stir-fry 2-5 minute (preferably stir-frying 4 minutes), take out, cool, for subsequent use;
(3) all the other the 9 taste crude drug except maple leaf, Folium Symplocoris Caudatae, Rhizoma Homalomenae, ramie leaf and Folium Pruni pseudocerasi are put into pot, add 9 taste crude drug gross weight 6.2-7.2 water (preferably adding the water of 9 taste crude drug gross weight 6.7 times) doubly, decoct 1.2 hours, leach medicinal liquid;
(4) step (1) gained medicinal residues being added step (3) fills in the pot of medicinal residues, add 9 taste crude drug gross weight 5-6 water (preferably adding the water of 9 taste crude drug gross weight 5.4 times) doubly, decoct after 45 minutes, add step (1) gained medicinal liquid, continue decoction 10 minutes, leach medicinal liquid;
(5) step (3) and step (4) gained medicinal liquid are merged, be condensed into the clear paste (being preferably condensed into the clear paste that relative density is 1.21) that relative density is 1.19-1.23;
(6) by step (2) and the mixing of step (5) gained, add sucrose and dextrin, sucrose: dextrin=3:1, the amount of sucrose is 2.8-4 times (amount of sucrose is 3.2 times of step (2) and step (5) gained gross weight) of step (2) and step (5) gained gross weight, stir, No. 1 sieve series grain, dry, granulate, to obtain final product.
The preparation method of described tablet is:
(1) Ramulus et Folium Bischofiae Javanicae leaf, Folium Symplocoris Caudatae, ramie leaf and Folium Pruni pseudocerasi decoct with water twice, amount of water is the 5.6-6.7 of four taste crude drug gross weights doubly (preferred amount of water is 6.4 times of four taste crude drug gross weights), each decoction 50 minutes, merge twice medicinal liquid, medicinal residues are for subsequent use;
(2) Rhizoma Homalomenae is ground into fine powder, crosses 100-130 mesh sieve (preferred mistake 120 mesh sieve), put into hot pot and fry, little fire stir-fries, stir-fry 20-35 time (preferably per minute stir-fry 30 times) per minute, and stir-fry 2-5 minute (preferably stir-frying 4 minutes), take out, cool, for subsequent use;
(3) all the other the 9 taste crude drug except maple leaf, Folium Symplocoris Caudatae, Rhizoma Homalomenae, ramie leaf and Folium Pruni pseudocerasi are put into pot, add 9 taste crude drug gross weight 6.2-7.2 water (preferably adding the water of 9 taste crude drug gross weight 6.7 times) doubly, decoct 1.2 hours, leach medicinal liquid;
(4) step (1) gained medicinal residues being added step (3) fills in the pot of medicinal residues, add 9 taste crude drug gross weight 5-6 water (preferably adding the water of 9 taste crude drug gross weight 5.4 times) doubly, decoct after 45 minutes, add step (1) gained medicinal liquid, continue decoction 10 minutes, leach medicinal liquid;
(5) step (3) and step (4) gained medicinal liquid merged, be condensed into the thick paste (being preferably condensed into the thick paste that relative density is 1.32) that relative density is 1.3-1.33,65 DEG C of dryings 18 hours, take out, are ground into fine powder, cross 120 mesh sieves;
(6) by step (2) and the mixing of step (5) gained, add soluble starch, the amount of soluble starch is the amount of the preferred soluble starch of 1/8-1/5(of step (2) and step (5) gained gross weight is 1/6 of step (2) and step (5) gained gross weight), stir, be pressed into the tablet of the heavy 0.5g of every sheet, obtain final product.
The preparation method of described pill is:
(1) Ramulus et Folium Bischofiae Javanicae leaf, Folium Symplocoris Caudatae, ramie leaf and Folium Pruni pseudocerasi decoct with water twice, amount of water is the 5.6-6.7 of four taste crude drug gross weights doubly (preferred amount of water is 6.4 times of four taste crude drug gross weights), each decoction 50 minutes, merge twice medicinal liquid, medicinal residues are for subsequent use;
(2) Rhizoma Homalomenae is ground into fine powder, crosses 100-130 mesh sieve (preferred mistake 120 mesh sieve), put into hot pot and fry, little fire stir-fries, stir-fry 20-35 time (preferably per minute stir-fry 30 times) per minute, and stir-fry 2-5 minute (preferably stir-frying 4 minutes), take out, cool, for subsequent use;
(3) all the other the 9 taste crude drug except maple leaf, Folium Symplocoris Caudatae, Rhizoma Homalomenae, ramie leaf and Folium Pruni pseudocerasi are put into pot, add 9 taste crude drug gross weight 6.2-7.2 water (preferably adding the water of 9 taste crude drug gross weight 6.7 times) doubly, decoct 1.2 hours, leach medicinal liquid;
(4) step (1) gained medicinal residues being added step (3) fills in the pot of medicinal residues, add 9 taste crude drug gross weight 5-6 water (preferably adding the water of 9 taste crude drug gross weight 5.4 times) doubly, decoct after 45 minutes, add step (1) gained medicinal liquid, continue decoction 10 minutes, leach medicinal liquid;
(5) step (3) and step (4) gained medicinal liquid merged, be condensed into the thick paste (being preferably condensed into the thick paste that relative density is 1.32) that relative density is 1.3-1.33,65 DEG C of dryings 18 hours, take out, are ground into fine powder, cross 120 mesh sieves;
(6) by step (2) and the mixing of step (5) gained, with water pill, the pill that particle diameter is 3mm is made, dry, to obtain final product.
The pharmacy security for the treatment of urethritis provided by the invention, effectively, to have no side effect.In addition, excellent results of the present invention also shows:
1, drug resistance and Drug resistance can not be produced; ;
2, scientific formula, the preparation method of various dosage form is simple, products obtained therefrom taking convenience, is easy to carry;
3, the object of radical cure can be reached, thorough treatment, not recur more;
4, medicine source extensively and price is comparatively cheap;
5, there is effect of spleen invigorating lung benefiting, eliminating damp-heat, invigorating the spleen and replenishing QI, removing toxic substances and promoting subsidence of swelling, blood circulation promoting and blood stasis dispelling, regulating QI to relieve pain, treatment urethritis determined curative effect, and Be very effective.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1cure a medicament for urethritis, the primary raw material medicine getting following weight parts is prepared from (every part is 360g): Fructus Corni 9 parts, Radix Chimonanthi praecocis 10 parts, 8 parts, Ramulus et Folium Bischofiae Javanicae leaf, Herba Ipomoeae Pes-Capraes 7 parts, Herba Lanceae Tibeticae 11 parts, Folium Symplocoris Caudatae 9 parts, Caulis Lonicerae 7 parts, Rhizoma Homalomenae 8 parts, Radix Melastomatis Sanguinei 6 parts, ramie leaf 10 parts, Radix Codonopsis 7 parts, Herba Lythri Salicariae 9 parts, Folium Pruni pseudocerasi 11 parts, japanese bugle herb grass 8 parts.
The preparation method of the medicament powder of above-mentioned treatment urethritis is:
(1) Ramulus et Folium Bischofiae Javanicae leaf, Folium Symplocoris Caudatae, ramie leaf and Folium Pruni pseudocerasi decoct with water twice, and amount of water is 5.6 times of four taste crude drug gross weights, each decoction 50 minutes, and merge twice medicinal liquid, medicinal residues are for subsequent use;
(2) Rhizoma Homalomenae is ground into fine powder, cross 160 mesh sieves, put into hot pot and fry, little fire stir-fries, and per minutely stir-fries 20 times, stir-fries 2 minutes, takes out, cools, for subsequent use;
(3) all the other the 9 taste crude drug except maple leaf, Folium Symplocoris Caudatae, Rhizoma Homalomenae, ramie leaf and Folium Pruni pseudocerasi are put into pot, add the water of 9 taste crude drug gross weight 6.2 times, decoct 1.2 hours, leach medicinal liquid;
(4) step (1) gained medicinal residues being added step (3) fills in the pot of medicinal residues, adds the water of 9 taste crude drug gross weight 5 times, decocts after 45 minutes, adds step (1) gained medicinal liquid, continues decoction 10 minutes, leaches medicinal liquid;
(5) step (3) and step (4) gained medicinal liquid merged, be condensed into the thick paste that relative density is 1.3,65 DEG C of dryings 18 hours, take out, are ground into fine powder, cross 180 mesh sieves;
(6) by step (2) and the mixing of step (5) gained, with 4g often bag subpackage, aseptic subpackaged and get final product.
The instructions of taking that gained of the present invention cures the medicament powder of urethritis is: oral, one day twice, each 4g, boiled water was taken after mixing it with water.
embodiment 2cure a medicament for urethritis, the primary raw material medicine getting following weight parts is prepared from (every part is 360g): Fructus Corni 15 parts, Radix Chimonanthi praecocis 14 parts, 15 parts, Ramulus et Folium Bischofiae Javanicae leaf, Herba Ipomoeae Pes-Capraes 14 parts, Herba Lanceae Tibeticae 16 parts, Folium Symplocoris Caudatae 14 parts, Caulis Lonicerae 13 parts, Rhizoma Homalomenae 14 parts, Radix Melastomatis Sanguinei 12 parts, ramie leaf 14 parts, Radix Codonopsis 15 parts, Herba Lythri Salicariae 13 parts, Folium Pruni pseudocerasi 15 parts, japanese bugle herb grass 13 parts.
The preparation method of the pharmacy particle agent of above-mentioned treatment urethritis is:
(1) Ramulus et Folium Bischofiae Javanicae leaf, Folium Symplocoris Caudatae, ramie leaf and Folium Pruni pseudocerasi decoct with water twice, and amount of water is 6.4 times of four taste crude drug gross weights, each decoction 50 minutes, and merge twice medicinal liquid, medicinal residues are for subsequent use;
(2) Rhizoma Homalomenae is ground into fine powder, cross 120 mesh sieves, put into hot pot and fry, little fire stir-fries, and per minutely stir-fries 30 times, stir-fries 4 minutes, takes out, cools, for subsequent use;
(3) all the other the 9 taste crude drug except maple leaf, Folium Symplocoris Caudatae, Rhizoma Homalomenae, ramie leaf and Folium Pruni pseudocerasi are put into pot, add the water of 9 taste crude drug gross weight 6.7 times, decoct 1.2 hours, leach medicinal liquid;
(4) step (1) gained medicinal residues being added step (3) fills in the pot of medicinal residues, adds the water of 9 taste crude drug gross weight 5.4 times, decocts after 45 minutes, adds step (1) gained medicinal liquid, continues decoction 10 minutes, leaches medicinal liquid;
(5) step (3) and step (4) gained medicinal liquid are merged, be condensed into the clear paste that relative density is 1.21;
(6) by step (2) and the mixing of step (5) gained, add sucrose and dextrin, sucrose: dextrin=3:1, the amount of sucrose is 3.2 times of step (2) and step (5) gained gross weight, stirs, No. 1 sieve series grain, and dry, granulate, to obtain final product.
model case one:grandson XX, female, 35 years old.Before more than 2 years, the symptoms such as leucorrhoea grow in quantity appears in patient, pudendal pruritus, check to nearby hospitals and are diagnosed as urethritis.Once took antibiotic etc treatment, and had no and be clearly better.Then to our hospital.Patient's pudendal pruritus, profuse leukorrhea, with frequent micturition, red tongue with yellowish and greasy fur, stringy and rolling pulse.Take the pharmacy particle agent that the present embodiment gained cures urethritis, one day twice, each 10g, boiled water was taken after mixing it with water.After taking 20 days, transference cure, to examination in hospital no abnormality seen.To follow up a case by regular visits to and without recurrence.
embodiment 3cure a medicament for urethritis, the primary raw material medicine getting following weight parts is prepared from (every part is 360g): Fructus Corni 11 parts, Radix Chimonanthi praecocis 11 parts, 10 parts, Ramulus et Folium Bischofiae Javanicae leaf, Herba Ipomoeae Pes-Capraes 9 parts, Herba Lanceae Tibeticae 12 parts, Folium Symplocoris Caudatae 10 parts, Caulis Lonicerae 9 parts, Rhizoma Homalomenae 10 parts, Radix Melastomatis Sanguinei 7 parts, ramie leaf 11 parts, Radix Codonopsis 9 parts, Herba Lythri Salicariae 10 parts, Folium Pruni pseudocerasi 12 parts, japanese bugle herb grass 9 parts.
The preparation method of the medicament tablet of above-mentioned treatment urethritis is:
(1) Ramulus et Folium Bischofiae Javanicae leaf, Folium Symplocoris Caudatae, ramie leaf and Folium Pruni pseudocerasi decoct with water twice, and amount of water is 6.4 times of four taste crude drug gross weights, each decoction 50 minutes, and merge twice medicinal liquid, medicinal residues are for subsequent use;
(2) Rhizoma Homalomenae is ground into fine powder, cross 120 mesh sieves, put into hot pot and fry, little fire stir-fries, and per minutely stir-fries 30 times, stir-fries 4 minutes, takes out, cools, for subsequent use;
(3) all the other the 9 taste crude drug except maple leaf, Folium Symplocoris Caudatae, Rhizoma Homalomenae, ramie leaf and Folium Pruni pseudocerasi are put into pot, add the water of 9 taste crude drug gross weight 6.7 times, decoct 1.2 hours, leach medicinal liquid;
(4) step (1) gained medicinal residues being added step (3) fills in the pot of medicinal residues, adds the water of 9 taste crude drug gross weight 5.4 times, decocts after 45 minutes, adds step (1) gained medicinal liquid, continues decoction 10 minutes, leaches medicinal liquid;
(5) step (3) and step (4) gained medicinal liquid merged, be condensed into the thick paste that relative density is 1.32,65 DEG C of dryings 18 hours, take out, are ground into fine powder, cross 120 mesh sieves;
(6) by step (2) and the mixing of step (5) gained, add soluble starch, the amount of soluble starch is 1/6 of step (2) and step (5) gained gross weight, stirs, and is pressed into the tablet of the heavy 0.5g of every sheet, obtains final product.
model case two:high XX, man, 48 years old.Before more than 1 year, patient occurs that urethral orifice is red and swollen because of unclean sexual life, and urethra such as to be itched at the symptom, to examination in hospital, examines as urethritis.Once take multiple Drug therapy, be showed no obvious improvement.Under the introduction of friend, to our hospital.Urinary road junction is red and swollen, and urethra is itched, causalgia during urine, and urethra has yellow secretions to flow out.Check: patient's redundant prepuce, reddened and swollen glans penis, secretions becomes yellow pus; Secretions plate coating checking is shown in a large amount of bacterial growth.Be diagnosed as urethritis.Take the medicament tablet that the present embodiment gained cures urethritis, one day twice, each 2, warm water took.Take 20 days, symptom is obviously improved.Continue to take 20 days, transference cure, unobstructed micturition, routine urianlysis is completely normal.Follow up a case by regular visits to urethritis not recur.
embodiment 4cure a medicament for urethritis, the primary raw material medicine getting following weight parts is prepared from (every part is 360g): Fructus Corni 14 parts, Radix Chimonanthi praecocis 13 parts, 14 parts, Ramulus et Folium Bischofiae Javanicae leaf, Herba Ipomoeae Pes-Capraes 12 parts, Herba Lanceae Tibeticae 14 parts, Folium Symplocoris Caudatae 13 parts, Caulis Lonicerae 11 parts, Rhizoma Homalomenae 13 parts, Radix Melastomatis Sanguinei 11 parts, ramie leaf 13 parts, Radix Codonopsis 13 parts, Herba Lythri Salicariae 12 parts, Folium Pruni pseudocerasi 14 parts, japanese bugle herb grass 12 parts.
The preparation method of the medicament pill of above-mentioned treatment urethritis is:
(1) Ramulus et Folium Bischofiae Javanicae leaf, Folium Symplocoris Caudatae, ramie leaf and Folium Pruni pseudocerasi decoct with water twice, and amount of water is 6.4 times of four taste crude drug gross weights, each decoction 50 minutes, and merge twice medicinal liquid, medicinal residues are for subsequent use;
(2) Rhizoma Homalomenae is ground into fine powder, cross 120 mesh sieves, put into hot pot and fry, little fire stir-fries, and per minutely stir-fries 30 times, stir-fries 4 minutes, takes out, cools, for subsequent use;
(3) all the other the 9 taste crude drug except maple leaf, Folium Symplocoris Caudatae, Rhizoma Homalomenae, ramie leaf and Folium Pruni pseudocerasi are put into pot, add the water of 9 taste crude drug gross weight 6.7 times, decoct 1.2 hours, leach medicinal liquid;
(4) step (1) gained medicinal residues being added step (3) fills in the pot of medicinal residues, adds the water of 9 taste crude drug gross weight 5.4 times, decocts after 45 minutes, adds step (1) gained medicinal liquid, continues decoction 10 minutes, leaches medicinal liquid;
(5) step (3) and step (4) gained medicinal liquid merged, be condensed into the thick paste that relative density is 1.32,65 DEG C of dryings 18 hours, take out, are ground into fine powder, cross 120 mesh sieves;
(6) by step (2) and the mixing of step (5) gained, with water pill, the pill that particle diameter is 3mm is made, dry, to obtain final product.
model case three:guo XX, man, 56 years old.Before half a year is remaining, patient occurs that urethral orifice is red and swollen, and urethra has the symptoms such as scorching hot, pain, takes multi-medicament, all without being clearly better.Then my institute's diagnosis and treatment.Urinary road junction is red and swollen, and dysurea, visible urethral orifice has faint yellow secretions to flow out, and underwear is stained with yellow secretions.Pale tongue, arteries and veins is soft.Result of laboratory test: urethral secretions smear WBC(leukocyte) count > 20, do not find G-diplococcus.And chlamydia is positive, mycoplasma is negative.Be diagnosed as urethritis.Take the medicament pill that the present embodiment gained cures urethritis, one day twice, each 4 balls, warm water took.Take 10 days, symptom is improved.Continue to take 1 month, symptom disappears completely, unobstructed micturition, and routine urianlysis is completely normal.Follow up a case by regular visits to urethritis not recur.
embodiment 5cure a medicament for urethritis, the primary raw material medicine getting following weight parts is prepared from (every part is 360g): Fructus Corni 13 parts, Radix Chimonanthi praecocis 12 parts, 12 parts, Ramulus et Folium Bischofiae Javanicae leaf, Herba Ipomoeae Pes-Capraes 11 parts, Herba Lanceae Tibeticae 13 parts, Folium Symplocoris Caudatae 12 parts, Caulis Lonicerae 10 parts, Rhizoma Homalomenae 11 parts, Radix Melastomatis Sanguinei 10 parts, ramie leaf 12 parts, Radix Codonopsis 11 parts, Herba Lythri Salicariae 10.5 parts, Folium Pruni pseudocerasi 13 parts, japanese bugle herb grass 11 parts.
The preparation method of the medicament powder of above-mentioned treatment urethritis is:
(1) Ramulus et Folium Bischofiae Javanicae leaf, Folium Symplocoris Caudatae, ramie leaf and Folium Pruni pseudocerasi decoct with water twice, and amount of water is 6.4 times of four taste crude drug gross weights, each decoction 50 minutes, and merge twice medicinal liquid, medicinal residues are for subsequent use;
(2) Rhizoma Homalomenae is ground into fine powder, cross 180 mesh sieves, put into hot pot and fry, little fire stir-fries, and per minutely stir-fries 30 times, stir-fries 4 minutes, takes out, cools, for subsequent use;
(3) all the other the 9 taste crude drug except maple leaf, Folium Symplocoris Caudatae, Rhizoma Homalomenae, ramie leaf and Folium Pruni pseudocerasi are put into pot, add the water of 9 taste crude drug gross weight 6.7 times, decoct 1.2 hours, leach medicinal liquid;
(4) step (1) gained medicinal residues being added step (3) fills in the pot of medicinal residues, adds the water of 9 taste crude drug gross weight 5.4 times, decocts after 45 minutes, adds step (1) gained medicinal liquid, continues decoction 10 minutes, leaches medicinal liquid;
(5) step (3) and step (4) gained medicinal liquid merged, be condensed into the thick paste that relative density is 1.32,65 DEG C of dryings 18 hours, take out, are ground into fine powder, cross 180 mesh sieves;
(6) by step (2) and the mixing of step (5) gained, with 4g often bag subpackage, aseptic subpackaged and get final product.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Fructus Corni: base is former: be the sarcocarp of Cornaceae plant Fructus Corni.The property of medicine: sour, puckery, tepor.Return liver, kidney channel.Function cures mainly: liver and kidney tonifying, essence astringing and desertion stemming.For vertigo and tinnitus, soreness of waist and knee joint, impotence and seminal emission, enuresis frequent micturition, bleeding not during menses, profuse sweating is collapsed, and interior-heat is quenched one's thirst.
Radix Chimonanthi praecocis: base is former: the root of Calycanthaceae wax prunus mume (sieb.) sieb.et zucc..The property of medicine: acrid in the mouth; Warm in nature; Poisonous.Return liver, lung meridian.Function cures mainly: wind-expelling pain-stopping; Vital energy regualting and blood circulation-promoting; Relieving cough and asthma.Main air pain of dampness syndrome; Anemofrigid cold; Traumatic injury; Epigastric pain; Asthma; Epersalgia cough; Furuncle swelling toxin.
Ramulus et Folium Bischofiae Javanicae leaf: base is former: be the leaf of Euphorbiaceae bishopwood plant Bischofia polycarpa.The property of medicine: bitter, puckery, cool.Function cures mainly: detoxicating and resolving stagnation of pathogens.Cure mainly dysphagic; Regurgitation; Infectious hepatitis, infantile malnutrition, pharyngalgia, skin infection.
Herba Ipomoeae Pes-Capraes: base is former: be the herb of dicotyledon scammonia section plant king crab rattan.The property of medicine: pungent; Bitter; Be slightly cold.Return liver, spleen channel.Function cures mainly: expelling wind and removing dampness; Eliminating carbuncle eliminating stagnation.Main air pain of dampness syndrome; Carbuncle; Furunculosis; Acute mastitis; Anal fistula.
Herba Lanceae Tibeticae: base is former: be the herb of goatweed Fructus Lanceae tibeticae.The property of medicine: sweet in the mouth; Bitter; Cold in nature.Function cures mainly: lung heat clearing; Evacuation of pus; Removing toxic substances; Detumescence.Main cough due to lung-heat; Lung abscess; Influenza; Dysentery; Laryngopharynx swelling and pain.
Folium Symplocoris Caudatae: base is former: be the leaf of Symplocaceae plant mountain vitriol.The property of medicine: acid; Puckery; Micro-sweet; Property is put down.Attach to the lung and stomach meridians.Function cures mainly: heat-clearing and toxic substances removing; Astringing to arrest bleeding.Main chronic dysentery; Wind-fire acute conjunctivitis, tonsillitis; Otitis media; Hemoptysis; Have blood in stool, thrush.
Caulis Lonicerae: base is former: for bearing the stem branch of section plant Radix Ophiopogonis, Lonicera confusa, wild rice gland Radix Ophiopogonis, Lonicera fulvotnetosa Hsu et S. C. Cheng. Ms etc.The property of medicine: sweet in the mouth; Cold in nature.GUIXIN, lung meridian.Function cures mainly: heat-clearing and toxic substances removing, dredging collateral.Main epidemic febrile disease heating, sore and toxic, toxic-heat and blood stasis, beriberoid pyretic arthralgia.
Rhizoma Homalomenae: base is former: be the rhizome of aroid Rhizoma Homalomenae.The property of medicine: bitter in the mouth; Pungent; Warm in nature; Mild toxicity.Return liver, kidney, stomach warp.Function cures mainly: wind-damp dispelling; Relaxing muscles and tendons and activating QI and blood in the collateral; Pain relieving; Detumescence.Main air pain of dampness syndrome; Podomere acid is educated; Muscles and bones flaccidity is soft; Traumatic injury; Stomachache; Carbuncle skin ulcer swells.
Radix Melastomatis Sanguinei: base is former: the leaf harvested for Melastomateae plants or Herb.The property of medicine: bitter in the mouth; Puckery; Cool in nature.Return spleen, Liver Channel.Function cures mainly: removing toxic substances pain relieving; Promoting regeneration of the tissue and arresting bleeding.Main eruptive disease stomachache; Dysentery; Have blood in stool; Menorrhagia; Furuncle; Treating swelling and pain by traumatic injury; Traumatic hemorrhage.
Ramie leaf: base is former: be the leaf of contrayerva Boehmeria.The property of medicine: sweet; Micro-hardship; Cold in nature.Return liver, heart channel.Function cures mainly: cooling blood for hemostasis; Dissipating blood stasis for subsidence of swelling; Removing toxic substances.Main spitting of blood; Spit blood; Stranguria with blood; Hematuria; Menorrhagia; Traumatic hemorrhage; Tumbling down swells and ache; Proctoptosis is not received; Erysipelas; Skin ulcer swells; Acute mastitis; Eczema; Snake bite and insect sting.
Radix Codonopsis: base is former: be the dry root of Campanulaceae Radix Codonopsis, element flower Radix Codonopsis or radix codonpsis tangshen etc.The property of medicine: sweet, flat.Return spleen, lung meridian.Function cures mainly: invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.For deficiency of the spleen and lung, cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency is coughed, and interior-heat is quenched one's thirst.
Herba Lythri Salicariae: base is former: be the herb of Lythraceae plant Herba Lythri Salicariae.The property of medicine: bitter in the mouth; Cold in nature.Return large intestine, Liver Channel.Function cures mainly: heat-clearing and toxic substances removing; Astringing to arrest bleeding.Main dysentery; Have loose bowels; Have blood in stool; Metrorrhagia; Skin infection festers; Spit blood; Epistaxis; Traumatic hemorrhage.
Folium Pruni pseudocerasi: base is former: be the leaf of rosaceous plant Fructus Pruni pseudocerasi.The property of medicine: sweet, bitter; Temperature; Nontoxic.Return liver, spleen, lung meridian.Function cures mainly: warming middle-JIAO and strengthening the spleen, and cough-relieving is stopped blooding, removing toxic substances parasite killing.Main cold syndrome of the stomach food stagnation; Diarrhoea; Cough; Spit blood; Skin infection swells carbuncle; Snake bite and insect sting, trichomonas vaginitis.
Japanese bugle herb grass: base is former: be herb or the root of the purple japanese bugle herb of labiate.The property of medicine: bitter in the mouth; Pungent; Cold in nature.Function cures mainly: heat-clearing and toxic substances removing; Cool the blood dissipate blood stasis; Reducing swelling and alleviating pain.Main cough due to lung-heat; Hemoptysis; Laryngopharynx swelling and pain; Acute mastitis; Intestinal carbuncle; Furuncle is hemorrhage; Treating swelling and pain by traumatic injury; Traumatic hemorrhage; Burn due to hot liquid or fire; Venom.
test example 1gained of the present invention cures the clinical practice of the medicament (embodiment 5) of urethritis: in January ,-2010 in June, 2008, screen 270 routine urethritis patients in 3 hospitals.Be divided into two groups at random, experimental group and matched group (often organizing 135 people).Experimental group women 74 example, male 61 example, 20 years old ~ 61 years old age, average 43.2 years old.Matched group women 76 example, male 59 example, 20 years old ~ 61 years old age, average 43.6 years old.Two groups of patients compare in the physical data such as sex, age, the course of disease, and there was no significant difference, has comparability.Experimental group uses gained of the present invention to cure the medicament of urethritis, and using method: oral, one day twice, each 4g, boiled water was taken after mixing it with water, and within 10 days, is a course for the treatment of.Matched group uses Flos Lonicerae to secrete the Drug therapys such as scorching clever sheet, Fibrauretinum tablets, SANJIN PIAN.After two groups of patients all treat four courses for the treatment of, carry out Comparison of therapeutic.
Curative effect situation criterion: cure: transference cure, unobstructed micturition, routine urianlysis is completely normal; Effective: symptom disappears substantially, urine routine test is normal.Invalid: before and after treatment, symptom is not improved.Total effectively comprising cures and effective.Result is as shown in table 1.
Table 1: gained of the present invention cures the pharmacy effect checking [example (%)] of urethritis
Therapeutic effect: in 135 routine patients of experimental group, cures 122 examples, accounts for 90.37%; Effective 11 examples, account for 8.15%; Invalid 2 examples, account for 1.48%; Total effective rate reaches 98.52%.In 135 routine patients of matched group, cure 83 examples, account for 61.48%; Effective 30 examples, account for 22.22%; Invalid 22 examples, account for 16.3%; Total effective rate is 83.7%.Experimental group total effective rate is obviously better than matched group, and two groups of comparing differences have significance.
The present invention is primary raw material medicine with Fructus Corni, Radix Chimonanthi praecocis, Ramulus et Folium Bischofiae Javanicae leaf and Herba Ipomoeae Pes-Capraes etc., makes the medicament of curing urethritis.Fructus Corni liver and kidney tonifying in side, essence astringing and desertion stemming.Radix Chimonanthi praecocis wind-expelling pain-stopping; Vital energy regualting and blood circulation-promoting; Relieving cough and asthma.Ramulus et Folium Bischofiae Javanicae leaf detoxicating and resolving stagnation of pathogens.Herba Ipomoeae Pes-Capraes expelling wind and removing dampness; Eliminating carbuncle eliminating stagnation.Herba Lanceae Tibeticae lung heat clearing; Evacuation of pus; Removing toxic substances; Detumescence.Folium Symplocoris Caudatae heat-clearing and toxic substances removing; Astringing to arrest bleeding.Caulis Lonicerae heat-clearing and toxic substances removing, dredging collateral.Rhizoma Homalomenae wind-damp dispelling; Relaxing muscles and tendons and activating QI and blood in the collateral; Pain relieving; Detumescence.Radix Melastomatis Sanguinei removing toxic substances pain relieving; Promoting regeneration of the tissue and arresting bleeding.Ramie leaf cooling blood for hemostasis; Dissipating blood stasis for subsidence of swelling; Removing toxic substances.Radix Codonopsis invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.Herba Lythri Salicariae heat-clearing and toxic substances removing; Astringing to arrest bleeding.Folium Pruni pseudocerasi warming middle-JIAO and strengthening the spleen, cough-relieving is stopped blooding, removing toxic substances parasite killing.Japanese bugle herb grass heat-clearing and toxic substances removing; Cool the blood dissipate blood stasis; Reducing swelling and alleviating pain.Many medicines share, and mutually coordinate, play the effect of liver and kidney tonifying, removing damp-heat, vital energy regualting and blood circulation-promoting, invigorating the spleen and replenishing QI, removing toxic substances pain relieving, dissipating blood stasis for subsidence of swelling, warming middle-JIAO and strengthening the spleen altogether, treatment urethritis determined curative effect, and Be very effective.
Finally it should be noted that, embodiment is the detailed description of the invention of optimum of the present invention, be not limited to the present invention, although with reference to previous embodiment to invention has been detailed description, for a person skilled in the art, it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (10)
1. cure a medicament for urethritis, it is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: Fructus Corni 9-15, Radix Chimonanthi praecocis 10-14, Ramulus et Folium Bischofiae Javanicae leaf 8-15, Herba Ipomoeae Pes-Capraes 7-14, Herba Lanceae Tibeticae 11-16, Folium Symplocoris Caudatae 9-14, Caulis Lonicerae 7-13, Rhizoma Homalomenae 8-14, Radix Melastomatis Sanguinei 6-12, ramie leaf 10-14, Radix Codonopsis 7-15, Herba Lythri Salicariae 9-13, Folium Pruni pseudocerasi 11-15, japanese bugle herb grass 8-13.
2. medicament of curing urethritis as claimed in claim 1, is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: Fructus Corni 11-14, Radix Chimonanthi praecocis 11-13, Ramulus et Folium Bischofiae Javanicae leaf 10-14, Herba Ipomoeae Pes-Capraes 9-12, Herba Lanceae Tibeticae 12-14, Folium Symplocoris Caudatae 10-13, Caulis Lonicerae 9-11, Rhizoma Homalomenae 10-13, Radix Melastomatis Sanguinei 7-11, ramie leaf 11-13, Radix Codonopsis 9-13, Herba Lythri Salicariae 10-12, Folium Pruni pseudocerasi 12-14, japanese bugle herb grass 9-12.
3. medicament of curing urethritis as claimed in claim 1, is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: Fructus Corni 13, Radix Chimonanthi praecocis 12, Ramulus et Folium Bischofiae Javanicae leaf 12, Herba Ipomoeae Pes-Capraes 11, Herba Lanceae Tibeticae 13, Folium Symplocoris Caudatae 12, Caulis Lonicerae 10, Rhizoma Homalomenae 11, Radix Melastomatis Sanguinei 10, ramie leaf 12, Radix Codonopsis 11, Herba Lythri Salicariae 10.5, Folium Pruni pseudocerasi 13, japanese bugle herb grass 11.
4. the medicament of the treatment urethritis as described in as arbitrary in claims 1 to 3, it is characterized in that, the medicament of this treatment urethritis is made pharmaceutically acceptable powder, and the preparation method of described powder is:
(1) Ramulus et Folium Bischofiae Javanicae leaf, Folium Symplocoris Caudatae, ramie leaf and Folium Pruni pseudocerasi decoct with water twice, amount of water is the 5.6-6.7 of four taste crude drug gross weights doubly (preferred amount of water is 6.4 times of four taste crude drug gross weights), each decoction 50 minutes, merge twice medicinal liquid, medicinal residues are for subsequent use;
(2) Rhizoma Homalomenae is ground into fine powder, cross 160-190 mesh sieve, put into hot pot and fry, little fire stir-fries, and per minutely stir-fries 20-35 time, and stir-fry 2-5 minute, and taking-up, cools, for subsequent use;
(3) all the other the 9 taste crude drug except maple leaf, Folium Symplocoris Caudatae, Rhizoma Homalomenae, ramie leaf and Folium Pruni pseudocerasi are put into pot, add 9 taste crude drug gross weight 6.2-7.2 water (preferably adding the water of 9 taste crude drug gross weight 6.7 times) doubly, decoct 1.2 hours, leach medicinal liquid;
(4) step (1) gained medicinal residues being added step (3) fills in the pot of medicinal residues, add 9 taste crude drug gross weight 5-6 water (preferably adding the water of 9 taste crude drug gross weight 5.4 times) doubly, decoct after 45 minutes, add step (1) gained medicinal liquid, continue decoction 10 minutes, leach medicinal liquid;
(5) step (3) and step (4) gained medicinal liquid merged, be condensed into the thick paste (being preferably condensed into the thick paste that relative density is 1.32) that relative density is 1.3-1.33,65 DEG C of dryings 18 hours, take out, are ground into fine powder, cross 180 mesh sieves;
(6) by step (2) and the mixing of step (5) gained, with 4g often bag subpackage, aseptic subpackaged and get final product.
5. the medicament of the treatment urethritis as described in as arbitrary in claims 1 to 3, it is characterized in that, the medicament of this treatment urethritis is made pharmaceutically acceptable granule, and the preparation method of described granule is:
(1) Ramulus et Folium Bischofiae Javanicae leaf, Folium Symplocoris Caudatae, ramie leaf and Folium Pruni pseudocerasi decoct with water twice, amount of water is the 5.6-6.7 of four taste crude drug gross weights doubly (preferred amount of water is 6.4 times of four taste crude drug gross weights), each decoction 50 minutes, merge twice medicinal liquid, medicinal residues are for subsequent use;
(2) Rhizoma Homalomenae is ground into fine powder, crosses 100-130 mesh sieve (preferred mistake 120 mesh sieve), put into hot pot and fry, little fire stir-fries, stir-fry 20-35 time (preferably per minute stir-fry 30 times) per minute, and stir-fry 2-5 minute (preferably stir-frying 4 minutes), take out, cool, for subsequent use;
(3) all the other the 9 taste crude drug except maple leaf, Folium Symplocoris Caudatae, Rhizoma Homalomenae, ramie leaf and Folium Pruni pseudocerasi are put into pot, add 9 taste crude drug gross weight 6.2-7.2 water (preferably adding the water of 9 taste crude drug gross weight 6.7 times) doubly, decoct 1.2 hours, leach medicinal liquid;
(4) step (1) gained medicinal residues being added step (3) fills in the pot of medicinal residues, add 9 taste crude drug gross weight 5-6 water (preferably adding the water of 9 taste crude drug gross weight 5.4 times) doubly, decoct after 45 minutes, add step (1) gained medicinal liquid, continue decoction 10 minutes, leach medicinal liquid;
(5) step (3) and step (4) gained medicinal liquid are merged, be condensed into the clear paste (being preferably condensed into the clear paste that relative density is 1.21) that relative density is 1.19-1.23;
(6) by step (2) and the mixing of step (5) gained, add sucrose and dextrin, sucrose: dextrin=3:1, the amount of sucrose is 2.8-4 times (amount of sucrose is 3.2 times of step (2) and step (5) gained gross weight) of step (2) and step (5) gained gross weight, stir, No. 1 sieve series grain, dry, granulate, to obtain final product.
6. the medicament of the treatment urethritis as described in as arbitrary in claims 1 to 3, it is characterized in that, the medicament of this treatment urethritis is made pharmaceutically acceptable tablet, and the preparation method of described tablet is:
(1) Ramulus et Folium Bischofiae Javanicae leaf, Folium Symplocoris Caudatae, ramie leaf and Folium Pruni pseudocerasi decoct with water twice, amount of water is the 5.6-6.7 of four taste crude drug gross weights doubly (preferred amount of water is 6.4 times of four taste crude drug gross weights), each decoction 50 minutes, merge twice medicinal liquid, medicinal residues are for subsequent use;
(2) Rhizoma Homalomenae is ground into fine powder, crosses 100-130 mesh sieve (preferred mistake 120 mesh sieve), put into hot pot and fry, little fire stir-fries, stir-fry 20-35 time (preferably per minute stir-fry 30 times) per minute, and stir-fry 2-5 minute (preferably stir-frying 4 minutes), take out, cool, for subsequent use;
(3) all the other the 9 taste crude drug except maple leaf, Folium Symplocoris Caudatae, Rhizoma Homalomenae, ramie leaf and Folium Pruni pseudocerasi are put into pot, add 9 taste crude drug gross weight 6.2-7.2 water (preferably adding the water of 9 taste crude drug gross weight 6.7 times) doubly, decoct 1.2 hours, leach medicinal liquid;
(4) step (1) gained medicinal residues being added step (3) fills in the pot of medicinal residues, add 9 taste crude drug gross weight 5-6 water (preferably adding the water of 9 taste crude drug gross weight 5.4 times) doubly, decoct after 45 minutes, add step (1) gained medicinal liquid, continue decoction 10 minutes, leach medicinal liquid;
(5) step (3) and step (4) gained medicinal liquid merged, be condensed into the thick paste (being preferably condensed into the thick paste that relative density is 1.32) that relative density is 1.3-1.33,65 DEG C of dryings 18 hours, take out, are ground into fine powder, cross 120 mesh sieves;
(6) by step (2) and the mixing of step (5) gained, add soluble starch, the amount of soluble starch is the amount of the preferred soluble starch of 1/8-1/5(of step (2) and step (5) gained gross weight is 1/6 of step (2) and step (5) gained gross weight), stir, be pressed into the tablet of the heavy 0.5g of every sheet, obtain final product.
7. the medicament of the treatment urethritis as described in as arbitrary in claims 1 to 3, it is characterized in that, the medicament of this treatment urethritis is made pharmaceutically acceptable pill, and the preparation method of described pill is:
(1) Ramulus et Folium Bischofiae Javanicae leaf, Folium Symplocoris Caudatae, ramie leaf and Folium Pruni pseudocerasi decoct with water twice, amount of water is the 5.6-6.7 of four taste crude drug gross weights doubly (preferred amount of water is 6.4 times of four taste crude drug gross weights), each decoction 50 minutes, merge twice medicinal liquid, medicinal residues are for subsequent use;
(2) Rhizoma Homalomenae is ground into fine powder, crosses 100-130 mesh sieve (preferred mistake 120 mesh sieve), put into hot pot and fry, little fire stir-fries, stir-fry 20-35 time (preferably per minute stir-fry 30 times) per minute, and stir-fry 2-5 minute (preferably stir-frying 4 minutes), take out, cool, for subsequent use;
(3) all the other the 9 taste crude drug except maple leaf, Folium Symplocoris Caudatae, Rhizoma Homalomenae, ramie leaf and Folium Pruni pseudocerasi are put into pot, add 9 taste crude drug gross weight 6.2-7.2 water (preferably adding the water of 9 taste crude drug gross weight 6.7 times) doubly, decoct 1.2 hours, leach medicinal liquid;
(4) step (1) gained medicinal residues being added step (3) fills in the pot of medicinal residues, add 9 taste crude drug gross weight 5-6 water (preferably adding the water of 9 taste crude drug gross weight 5.4 times) doubly, decoct after 45 minutes, add step (1) gained medicinal liquid, continue decoction 10 minutes, leach medicinal liquid;
(5) step (3) and step (4) gained medicinal liquid merged, be condensed into the thick paste (being preferably condensed into the thick paste that relative density is 1.32) that relative density is 1.3-1.33,65 DEG C of dryings 18 hours, take out, are ground into fine powder, cross 120 mesh sieves;
(6) by step (2) and the mixing of step (5) gained, with water pill, the pill that particle diameter is 3mm is made, dry, to obtain final product.
8. the preparation method curing the medicament powder of urethritis as claimed in claim 4, is characterized in that, crosses 180 mesh sieves in step (2).
9. the as claimed in claim 4 preparation method curing the medicament powder of urethritis, is characterized in that, per minutely in step (2) stir-fries 30 times.
10. the preparation method curing the medicament powder of urethritis as claimed in claim 4, is characterized in that, stir-fry 4 minutes in step (2).
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| CN111358719A (en) * | 2020-03-18 | 2020-07-03 | 西北师范大学白银师科创新研究院 | Chinese herbal medicine lipstick with cheilitis preventing function and preparation method thereof |
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| CN101104044A (en) * | 2007-06-14 | 2008-01-16 | 张红梅 | Traditional Chinese medicine formula for treating urinary infection |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101104044A (en) * | 2007-06-14 | 2008-01-16 | 张红梅 | Traditional Chinese medicine formula for treating urinary infection |
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| 万力生，杨卓欣主编: "《全科医师临床医嘱速查 第2版》", 31 August 2011, 人民军医出版社 * |
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| CN111358719A (en) * | 2020-03-18 | 2020-07-03 | 西北师范大学白银师科创新研究院 | Chinese herbal medicine lipstick with cheilitis preventing function and preparation method thereof |
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