CN103263538A - Traditional Chinese medicine combination with nourishing, anti-inflammation, antidiarrheal, hemostatic and analgesic effects for livestock and preparation method thereof - Google Patents
Traditional Chinese medicine combination with nourishing, anti-inflammation, antidiarrheal, hemostatic and analgesic effects for livestock and preparation method thereof Download PDFInfo
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Abstract
The invention is a traditional Chinese medicine combination with nourishing, anti-inflammation, antidiarrheal, hemostatic and analgesic effects for livestock. This traditional Chinese medicine combination is prepared in accordance with following ingredients by weight: 50-100 parts of Artemisia sacrorum Ledeb, 8-16 parts of ginseng, 8-16 parts of Astragalus, 5-10 parts of fructus schisandrae, 8-16 parts of Pericarpium Granati, 20-30 parts of Carthamus tinctorius and 0.1-0.3 part of saffron crocus. Through the clinic research, the set traditional Chinese medicines are successfully obtained. Indications of this traditional Chinese medicine: diarrhea, abdominal pain, loose stool, water stool, and blood stool; the cure rate is over 97%; fowls and livestock can be cured within 3 days in general. The product prepared by an optimal preparation technology as used in the invention has the good stability.
Description
Technical field
The present invention relates to Chinese medicine, a kind of Chinese medicine composition to poultry nourishing and antiinflammatory, antidiarrheal, hemostasis, analgesic effect and preparation method thereof specifically.
Background technology
For a long time, people are inquiring into Chinese medicine to people's value, purposes, effect.But Chinese medicine is to the therapeutic effect of poultry, domestic animal, can reach desirable very little; Though this research is also carried out continual, only be some disease at poultry, domestic animal colony, and the physical and mental health of poultry, domestic animal is not improved comprehensively yet.A kind ofly can not carry out Comprehensive Treatment and nourishing conditioning comprehensively to the multiple disease of crowd and poultry, domestic animal to modern seeing, reach crowd and poultry, domestic animal is physically and mentally healthy and multiple disease is had the herbal species of higher cure rate.
Summary of the invention
An object of the present invention is to provide a kind of Chinese medicine composition to poultry nourishing antiinflammatory antidiarrheal hemostasis and pain-relieving.
Another object of the present invention provides the preparation method of above-mentioned Chinese medicine composition.
In order to realize purpose of the present invention, a kind of Chinese medicine composition to poultry nourishing antiinflammatory antidiarrheal hemostasis and pain-relieving is proposed, this Chinese medicine composition is prepared from by following ingredients by weight;
Herba Artemisiae 50-100 part, Radix Ginseng 8-16 part, Radix Astragali 8-16 part, five tastes seed 5-10 part, Pericarpium Granati 8-16, Flos Carthami 20-30 part, Stigma Croci 0.1-0.3 part.
The present invention to described Chinese medicine composition also preferred following 3 kinds of concrete one-tenth by weight be grouped into;
75 parts of Herba Artemisiaes, 12 parts of Radix Ginsengs, 12 parts of the Radixs Astragali, 8 parts of five tastes seeds, 12 parts of Pericarpium Granatis, 25 parts on Flos Carthami, 0.15 part of Stigma Croci.
50 parts of Herba Artemisiaes, 16 parts of Radix Ginsengs, 16 parts of the Radixs Astragali, 10 parts of five tastes seeds, 16 parts of Pericarpium Granatis, 30 parts on Flos Carthami, 0.3 part of Stigma Croci.
100 parts of Herba Artemisiaes, 8 parts of Radix Ginsengs, 8 parts of the Radixs Astragali, 5 parts of five tastes seeds, 8 parts of Pericarpium Granatis, 20 parts on Flos Carthami, Stigma Croci .0.1 part.
Chinese medicine composition of the present invention can be made various types of pharmaceutical preparatioies according to actual needs, for example makes oral liquid or injection, and is preferred but be not limited to oral liquid.In order to prepare these preparations, can in compositions of the present invention, add conventional pharmaceutically acceptable auxiliaries as required, selection for adjuvant, those skilled in the art can carry out according to the requirement of dosage form, when for example preparing oral liquid, in the present composition, can add sweeting agent, flavoring agent and antiseptic.For the concrete selection of adjuvant, the present invention's specific restriction useless.
The present invention also proposes the preparation method of described Chinese medicine composition, and the method comprising the steps of:
Step 1: with 7 flavor raw material of Chinese medicine of 75 parts of above Herba Artemisiaes, 12 parts of Radix Ginsengs, 12 parts of the Radixs Astragali, 8 parts of five tastes seeds, 12 parts of Pericarpium Granatis, 25 parts on Flos Carthami, 0.15 part of Stigma Croci, powder becomes coarse powder, adds in the extraction pot;
Step 2: add above 7 flavor raw material of Chinese medicine quality 6-8 pure water doubly, open the automatic converter of vacuum, be decompressed to negative pressure 0.5-1MP, and be heated to and boil, keep slight boiling condition, carry out the economic benefits and social benefits concentrating return-flow, dynamic extraction 2-4 hour;
Step 3: collect extracting solution, extracting solution is evaporated to relative density 1.5-1.6;
Step 4: close heater, return to atmospheric pressure gradually;
Step 5: carry out spray drying, elder generation at 160 ℃ of preheating temperature 10-20 minutes, is set at 150-200 ℃ with inlet temperature with drying tower, and leaving air temp is set 50-100 ℃, pan feeding flow 1.2L/ branch;
Step 6: after all having sprayed, continue to keep air intake after 5 minutes, open the discharge bucket discharging, obtain dry powder;
Step 7: dry powder is prepared into various dosage forms.
The preparation method that above-mentioned dry powder is prepared oral liquid is:
Described dry powder with 100 times of pure water dilutions, is added orange juice, white sugar, brown sugar then, and adjust total amount embedding, sterilization, packing, namely get oral liquid.
The preparation method for preparing the powder of described Chinese medicine composition is:
Step 1: with Herba Artemisiae be cut into 1 centimeter little disconnected, enter the drying chamber oven dry, when moisture carries out crushing screening 10% the time, to reach being advisable of standard edible flour;
Step 2: the Radix Astragali is cut into 1 centimeter little breaks, enter the drying chamber oven dry, carry out crushing screening;
Step 3: with the other drug composition pulverize in the same way finish after, the multi-flavor medicine is combined, sieve then, multi-flavor medicine mix homogeneously reaches till the standard;
Step 4: the laboratorian extracts specimen and detects, detect up to standard after, can enter workshop pack, seal packing, sterilization;
In the preparation of the powder of described Chinese medicine composition, after pulverizing every Herba indigoferae Pseudotinctoriae that the medicine cleaning is clean, in order to avoid cause medicament mixed during Herba indigoferae Pseudotinctoriae under pulverizing, the ratio inequality influences drug effect or has side effects.
Above-mentioned raw material and equipment is commercially available arriving all.
Need to prove that method of the present invention is a kind of preferable preparation technique but is not limited to this.Product by the inventive method preparation has good stability.
For many years, the present invention is through clinical verification 3473 times, successfully obtains described Chinese traditional patent formulation to poultry nourishing antiinflammatory antidiarrheal hemostasis and pain-relieving, and this Chinese medicine composition Cheng Fang cures mainly: diarrhoea, stomachache, loose stool, water just, hemafecia; Cure rate is more than 97%; Poultry, domestic animal generally can be cured in 3 days.
Chinese medicine composition of the present invention is the best good medicine of crowd and poultry, domestic animal antidiarrheal, hemostasis, pain relieving.A word according to Huangdi's Internal Classics is summed up, and that is exactly " YIN and YANG in a relative equilibrium " for this medicine.The moon here refers to cloudy smart; Sun refers to gas.Cloudy smart interior plain, yang-energy is solid secret outside, people's vital essence and mind, the tranquil body that is present in.The characteristics of this medicine be exactly enrich cloudy smart, Gu secret yang-energy only in this way just can demonstrate the vitality of people's tanacity.Poultry, domestic animal are also like this.On this basis, be equipped with the flat medicine of mending the acid receipts, the medicine of flat benefit has Radix Ginseng, the Radix Astragali.
Functional component to poultry nourishing antiinflammatory antidiarrheal hemostasis and pain-relieving Chinese medicine composition of the present invention is Herba Artemisiae, Radix Ginseng, the Radix Astragali, five tastes seed, Pericarpium Granati, Flos Carthami, Stigma Croci.
In the prescription of the Chinese medicine composition to poultry nourishings antiinflammatory antidiarrheal hemostasis and pain-relieving of the present invention: put down in writing according to the Chinese medicine voluminous dictionary:
Herba Artemisiae, meridian distribution of property and flavor: bitter, hot, flat.Function cures mainly: heat-clearing and toxic substances removing, cooling blood and relieving pain.Be used for hepatitis, appendicitis, infantile convulsion, deficiency of YIN hectic fever; Wound hemorrhage is controlled in external." national Chinese herbal medicine compilation "
Radix Ginseng, strongly invigorating primordial QI, invigorating the lung and benefiting vital QI promotes the production of body fluid, the mind calming and mentality promoting, we attain a yet higher goal nourishing function with the auxiliary Herba Artemisiae of Radix Ginseng.Radix Ginseng is the easiest gets angry, and Herba Artemisiae is sweet cold, matches with Herba Artemisiae, does not have get angry biased, and Radix Ginseng is mended gas in the intestinal.
The Radix Astragali is gone into the spleen lung meridian, and tonifying Qi and lifting yang is arranged, the solid hidroschesis, diuretic detumescent effect in we with the same usefulness of Radix Ginseng, have powerful QI invigorating effect.
Five tastes seed, nature and flavor acid temperature is gone into the lung kidney channel, the nourishing kidney of astringing the lung, arresting seminal emission antidiarrheal, arresting sweating promotes the production of body fluid." herbal classic " cloud: " five tastes seed, main QI invigorating is coughed gas, a little less than the impairment caused by overstrain, tonifying for the deficiency, strong liver, beneficial man's warp ".
Pericarpium Granati, the sour and astringent temperature of nature and flavor is gone into large intestine channel, the astringing intestine to stop diarrhea hemostasis, this medicine has the effect of convergence whole body QI and blood, and gas is not loose outward, and having created for five tastes seed receipts vigour must conditio sune qua non.
Flos Carthami, promoting blood circulation to restore menstrual flow, blood stasis removing pain relieving.Control amenorrhea, lump in the abdomen, difficult labour, stillborn fetus, disease that postpartum lochia can't go, blood stasis are had a pain, carbuncle, injury from falling down.
Stigma Croci, sweet in flavor and cold in property, the effect stasis-dispelling and pain-killing adds some Stigma Crocis in right amount, matches with Flos Carthami, strengthens the merit of its blood-cleaning detoxifying, and effect is better.
With the medical material in the above-mentioned prescription by weight ratio complex group be fitted together, have following effect:
1, pure Chinese medicinal preparation, pure green medicine, combination is novel, science, rationally, medicine is pollution-free, and noresidue has no side effect.Human body is had no effect.
2, cure mainly: diarrhoea, stomachache, loose stool, water just, hemafecia; Curative effect is outstanding, and effect is remarkable, and dosage is few, and cost is low, the short treating period instant effect, and cure rate is more than 97%; Poultry, domestic animal generally can be cured in 3 days.
3, this prescription is new and effective antibiotic, antiviral drug, and it has antibiotic, and chemicals does not have the advantage of desirableization.
4, this prescription can be eliminated the sinister element of intestinal and the endotoxin in poultry, the tame carcass rapidly, improves body's immunity.
5, participate in reconciling the body biochemical reaction, reconcile nerve, cardiovascular, the function of digestive system.
6, the protection heart strengthens the gastrointestinal absorbability, and very strong receipts wound anti-diarrhea effect is arranged, and lasting medicine is stable.
For this reason, another object of the present invention provides the application of a kind of present composition in the medicine for preparing nourishing and antiinflammatory, antidiarrheal, hemostasis, pain relieving.
(pharmacological toxicology) this product tool broad-spectrum antibacterial action is especially to aerobic Grain-negative antibacterial activity height, to following antibacterial, the good antibacterial action of tool in vivo and in vitro, most of antibacterial of enterobacteriaceae comprises Bacillus, the cloaca, clostridium perfringen, especially all uncommon to the large intestine dust, gastrointestinal infection, Klebsiella, Proteus, Salmonella, Shigella, intestinal bar section antibacterial, the woods autumn bacterium, pasteurellosis bacillus, staphylococcus etc.; Often to multi-drug resistant bacteria tool good antibacterial activity, to dense courageous and upright streptococcus and fecal bacteria, specific antibacterial activity, to dense courageous and upright streptococcus and fecal bacteria, specific antibacterial activity, to mycoplasma, legionella tool good resistance microbial action.
The blood concentration of (overdose) this product should not surpass 200g/ml, surpasses this concentration, and the untoward reaction rate increases, and toxicity strengthens, and excessive short-term is taken this product inappetence can occur, feel sick vomiting, dizziness, headache, obnubilation, spirit is overcast, heating, hematuria, crystalluria, hematologic disease.
(points for attention)
1. oral liquid of the present invention or powder are put into the drink groove and carried out medicine feed, the staff notes observing the overall process of medication.
2. to refusing to eat fowl, manually medication by force.
3. note 1 age in week of poultry, general feeding method is without crib, and it is an amount of that the staff must carefully observe the drink medicine of poult.
4. sick fowl is hived off before the medicine feed, " optimal classification is the initial stage, mid-term " reached the recovery from illness effect as far as possible.
5. by the weight of sick fowl, strengthen dosage.
6. must by specification, by rule of operation operation medication, avoid drug intoxication.
(pharmacokinetics)
Clothes backs absorbs fully from gastrointestinal, and bioavailability reaches 95%-100%, and blood medicine peak time (Tmclx) is about 1 hour, food to the inhalation effects of this product seldom, behind the multiple dosing, steady plasma-drug concentration (CSS).Reached blood after the administration on the 3rd day and eliminate the half-life (ty) and be about 4.8-7 hour, protein binding rate is 20%-25%.
After this product absorbed, each tissue that extensively distributes, body fluid were to the intestinal wall film, and intestinal wall matter plays repairs to returning former effect, and in each tissue of body, concentration often surpasses blood drug level, and reaches effect level, and this product is passed through placental barrier.
This product mainly with original shape from renal excretion, a small amount of 3% at intrahepatic metabolism, the 75%-90% that gets rid of dosage in oral 24 hours in the urine, metabolite seldom in the urine, this product is a small amount of to get rid of in feces, after the administration in 24 hours and 48 hours, the accumulation output, is respectively 1.6% and 3.9% this product of dosage and also can lets out by the milk branch.
(storage) lucifuge, sealing is preserved (being no more than 20 ℃) at shady and cool dry place
Bottled 1 * 500 * 12/ box of (packing) liquid plastics
(effect duration) 18 months.
The specific embodiment
Embodiment 1
Clothes liquid preparation (ProductName: fowl is happy peaceful)
Raw material of Chinese medicine and consumption:
Herba Artemisiae 7.5kg, Radix Ginseng 1.2kg, Radix Astragali 1.2kg, five tastes seed 0.8kg, Pericarpium Granati 1.2kg, Flos Carthami 2.5kg, Stigma Croci 0.015kg, orange juice 2.3kg, white sugar 1.2kg, brown sugar 1.8kg.
The preparation method concrete steps are as follows:
Step 1: with the dried medicine raw material of Herba Artemisiae, Radix Ginseng, the Radix Astragali, five tastes seed, Pericarpium Granati, Flos Carthami, Stigma Croci seven flavor Chinese medicines clean, clean, drying, be ground into coarse powder, standby;
Step 2: the coarse powder of step 1 is weighed by weight: Herba Artemisiae 7.5kg, Radix Ginseng 1.2kg, Radix Astragali 1.2kg, five tastes seed 0.8kg, Pericarpium Granati 1.2kg, Flos Carthami 2.5kg, Stigma Croci 0.015kg add in the extraction pot, add above 7 flavor raw material of Chinese medicine quality 6-8 pure water doubly, open the automatic converter of vacuum, be decompressed to negative pressure 0.5-1MP, and be heated to and boil, keep slight boiling condition, carry out the economic benefits and social benefits concentrating return-flow, dynamic extraction 3 hours;
Step 3: collect extracting solution, extracting solution is evaporated to relative density 1.5;
Step 4: close heater, return to atmospheric pressure gradually;
Step 5: carry out spray drying, earlier with drying tower 160 ℃ of preheating temperatures 15 minutes, inlet temperature is set at 180 ℃, leaving air temp is set 80 ℃, pan feeding flow 1.2L/ branch;
Step 6: after all having sprayed, continue to keep air intake after 5 minutes, open the discharge bucket discharging, obtain dry powder;
Step 7: dry powder with 100 times of pure water dilutions, is added orange juice 2.3kg, white sugar 1.2kg, brown sugar 1.8kg then, and adjust total amount embedding, sterilization, packing, namely get oral liquid.
Usage and dosage: oral liquid is noted: per kilogram of body weight 3～5ml, every day 1～2 time, (consumption is decided by the fowl size).
Embodiment 2
Oral liquid (dog is happy peaceful)
Raw material of Chinese medicine and consumption:
Herba Artemisiae 5.0kg, Radix Ginseng 1.6kg, Radix Astragali 1.6kg, five tastes seed 1.0kg, Pericarpium Granati 1.6kg, Flos Carthami 3.0kg, Stigma Croci 0.03kg, orange juice 2.5kg, white sugar 1.5kg, brown sugar 2.0kg.
Step 1: with the dried medicine raw material of Herba Artemisiae, Radix Ginseng, the Radix Astragali, five tastes seed, Pericarpium Granati, Flos Carthami, Stigma Croci seven flavor Chinese medicines clean, clean, drying, be ground into coarse powder, standby;
Step 2: the coarse powder of step 1 is weighed by weight: Herba Artemisiae 7.5kg, Radix Ginseng 1.2kg, Radix Astragali 1.2kg, five tastes seed 0.8kg, Pericarpium Granati 1.2kg, Flos Carthami 2.5kg, Stigma Croci 0.03kg add in the extraction pot, add above 7 flavor raw material of Chinese medicine quality 6-8 pure water doubly, open the automatic converter of vacuum, be decompressed to negative pressure 0.5-1MP, and be heated to and boil, keep slight boiling condition, carry out the economic benefits and social benefits concentrating return-flow, dynamic extraction 3 hours;
Step 3: collect extracting solution, extracting solution is evaporated to relative density 1.5;
Step 4: close heater, return to atmospheric pressure gradually;
Step 5: carry out spray drying, earlier with drying tower 160 ℃ of preheating temperatures 15 minutes, inlet temperature is set at 180 ℃, leaving air temp is set 80 ℃, pan feeding flow 1.2L/ branch;
Step 6: after all having sprayed, continue to keep air intake after 5 minutes, open the discharge bucket discharging, obtain dry powder;
Step 7: dry powder with 100 times of pure water dilutions, is added orange juice 2.3kg, white sugar 1.2kg, brown sugar 1.8kg then, and adjust total amount embedding, sterilization, packing, namely get oral liquid.Usage and dosage: oral liquid is noted: per kilogram of body weight 1～3ml, and every day 1～2 time,
Embodiment 3
Powder preparation (pig is happy peaceful)
Raw material of Chinese medicine and consumption:
Herba Artemisiae 10.0kg, Radix Ginseng 0.8kg, Radix Astragali 0.8kg, five tastes seed 0.5kg, Pericarpium Granati 0.8kg, Flos Carthami 2.0kg, Stigma Croci 0.01kg.
The preparation method for preparing the powder of described Chinese medicine composition is:
Step 1: with Herba Artemisiae be cut into 1 centimeter little disconnected, enter the drying chamber oven dry, when moisture carries out crushing screening 10% the time, to reach being advisable of standard edible flour;
Step 2: the Radix Astragali is cut into 1 centimeter little breaks, enter the drying chamber oven dry, carry out crushing screening;
Step 3: with the other drug composition pulverize in the same way finish after, the multi-flavor medicine is combined, sieve then, multi-flavor medicine mix homogeneously reaches till the standard;
Step 4: the laboratorian extracts specimen and detects, detect up to standard after, can enter workshop pack, seal, packing, the sterilization powder preparation gets powder preparation.
In the preparation of the powder of described Chinese medicine composition, after pulverizing every Herba indigoferae Pseudotinctoriae that the medicine cleaning is clean, in order to avoid cause medicament mixed during Herba indigoferae Pseudotinctoriae under pulverizing, the ratio inequality influences drug effect or has side effects.
Usage and dosage: oral powder preparation is noted: per kilogram of body weight 1～3g, and every day 1～2 time,
Embodiment 4
Treat the clinical trial of disease chicken
Clinical symptoms:
Sick chicken spirit is depressed, and feed consumption reduces, and becomes thin; The broodiness of hen strengthens, and egg production descends; Slight until serious respiratory symptom, comprise cough, sneeze and shed tears in a large number; Head and face's edema, neurological disorders and diarrhoea.
3 groups of sick chickens are carried out the clinical experiment treatment, every group of 100 ill chickens, therapeutic outcome sees the following form:
1, uses " the liquid preparation of embodiments of the invention 1 (ProductName: happy No. one of fowl) treatment sick chicken effect observation catalog (experimental group)
2, the sick dog clinical trial for the treatment of
Clinical symptoms:
Sick dog spirit is depressed, and appetite is useless exhausted, and nervous symptoms appears in the sick dog that fervescence more than 40 ℃, vomiting, ophthalmic have a large amount of viscosity, the purulence eye corner of the eyes, asoscope drying, have: i.e. intermittent attacks such as spasm, epilepsy, tic.The appearance that continues diarrhoea, have blood in stool, brick-red, color of soy sauce, cerise do not wait, and occur serious dehydration phenomenon after three days, atrophy of eyeball, and skin elasticity descends, and has pinched the skin gauffer and has disappeared slow.Because acidosis appears in dehydration, heart failure and death.
3 groups of ill dogs are carried out the clinical experiment treatment, suffer from dog for 80 every group, therapeutic outcome sees the following form:
1, uses " embodiments of the invention 2 oral liquids (dog is happy peaceful) treatment ill dog effect observation catalog (experimental group)
3 groups of sick dogs are carried out the clinical experiment treatment, every group of 80 ill dogs, therapeutic outcome sees the following form:
Contrast treatment from the oral liquid (dog is happy peaceful) of above-mentioned application embodiments of the invention 2.Result of the test shows that oral liquid (dog the is happy peaceful) cure rate of using embodiments of the invention 2 can reach 98%.
3, the sick pig clinical trial for the treatment of
Clinical symptoms:
The test determination result of use
Test 1
Dongchang District pig farm, Tonghua, Jilin Province city, 100 of the numerous sows of energy are from numerous autotrophy, just ablactational baby pig is 100, the wean back began diarrhoea to occur on the 3rd day, drew yellow green feces, lassitude, part is with symptoms of emesis, body temperature is normal, morbidity back amikacin, ceftiofur, the ribavirin medicine is treated, and treats 4 days, but there is not positive effect, the state of an illness increases the weight of on the contrary day by day, after use Chinese medicine composition of the present invention instead, the powder preparation of embodiment 3 (pig happy peaceful) 1kg spice 100kg, mixed feeding, just saw positive effect on the 2nd day, in the time of the 3rd day, 92 normal, there are 8 symptom of diarrhea is arranged, effective percentage is 92%, the 5 day, and 97% above pig only recovers normal, no longer include symptom of diarrhea, obtain the obvious treatment effect.
Test 2
On a plurality of pig farms of Erdaojiang District, Tonghua, Jilin Province city, choose totally 200 of 21 age in days piglets, be divided into 2 groups at random, test group and matched group, every group each 100, the 1st group is test group (powder preparation of embodiment 3 (pig is happy peaceful) 5kg Chinese medicine composition makes an addition in the 1000kg feedstuff and mixes), the 2nd group is that matched group (adds in the colistin sulfate 20mg/kg feedstuff, mixed feeding), test group is identical with the matched group feeding and management, is used in conjunction 10 days.To the prevention diarrhea of pigs, obtain positive effect, result's following (seeing Table 1):
Table 1 prophylactic tria result
A morbidity number refers to that a pig quantity of symptom of diarrhea appears in drug withdrawal after the medication in 15 days.
Prevent effective number to refer to occur in 15 days after the medication pig quantity of symptom of diarrhea.
Wherein matched group in the time of the 5th day, namely have pig diarrhoea only to occur, and test group just has pig diarrhoea only to occur at the drug withdrawal hands in the time of the 12nd day in drug withdrawal.For only the diarrhoea pig occurring, give Chinese medicine composition, to add in the feedstuff according to 1% consumption, mixed feeding is used in conjunction 5 days, and pig is only no longer suffered from diarrhoea, and obtains obvious therapeutic effect.
Test 3
Meihekou City pig farm, Jilin Province, 100 of delivery room piglets, factor causes diarrhoea because climate change, feeding and management be improper etc. at 20 ages in days.Mainly show following clinical symptoms: suffer from diarrhoea suddenly, number of times does not wait, and discharges pasty state or watery stools, and color is milky white or greyish white, and flavor is stench, and property is sticky.The swine diseases lethargy is slow in action, hogback, and thick disorderly unglazed by hair, body surface is unclean, and root of the tail often is stained with feces, and happiness is slept, and sucking reduces or is useless exhausted, thirsty good drinking-water that has.According to above-mentioned condition of illness and epidemiological analysis, be diagnosed as piglet pujos blancos.Powder preparation (pig is happy peaceful) the 2kg Chinese medicinal composition granules of embodiment 3 is dissolved in the 200kg water, drinks to piglet, be used in conjunction 5 days.After using the 2nd day, diarrhoea stops, and the 3rd day, feces was shaped, and appetite is recovered gradually, and in the time of the 5th day, it is normal that feces, appetite, spirit are all recovered.
More than example of the present invention is had been described in detail, but described content only is preferred embodiments of the present invention, can not be considered to for limiting practical range of the present invention.All equalizations of doing according to the present patent application scope change and improve etc., all should belong within the patent covering scope of the present invention.
Claims (9)
1. the Chinese medicine composition to poultry nourishing antiinflammatory antidiarrheal hemostasis and pain-relieving is characterized in that this Chinese medicine composition is prepared from by following ingredients by weight;
Herba Artemisiae 50-100 part, Radix Ginseng 8-16 part, Radix Astragali 8-16 part, five tastes seed 5-10 part, Pericarpium Granati 8-16, Flos Carthami 20-30 part, Stigma Croci 0.1-0.3 part.
2. the Chinese medicine composition to poultry nourishing antiinflammatory antidiarrheal hemostasis and pain-relieving according to claim 1 is characterized in that described Chinese medicine composition is prepared from by following ingredients by weight;
75 parts of Herba Artemisiaes, 12 parts of Radix Ginsengs, 12 parts of the Radixs Astragali, 8 parts of five tastes seeds, 12 parts of Pericarpium Granatis, 25 parts on Flos Carthami, 0.15 part of Stigma Croci.
3. the Chinese medicine composition to poultry nourishing antiinflammatory antidiarrheal hemostasis and pain-relieving according to claim 1 is characterized in that described Chinese medicine composition is prepared from by following ingredients by weight;
50 parts of Herba Artemisiaes, 16 parts of Radix Ginsengs, 16 parts of the Radixs Astragali, 10 parts of five tastes seeds, 16 parts of Pericarpium Granatis, 30 parts on Flos Carthami, 0.3 part of Stigma Croci.
4. the Chinese medicine composition to poultry nourishing antiinflammatory antidiarrheal hemostasis and pain-relieving according to claim 1 is characterized in that described Chinese medicine composition is prepared from by following ingredients by weight;
100 parts of Herba Artemisiaes, 8 parts of Radix Ginsengs, 8 parts of the Radixs Astragali, 5 parts of five tastes seeds, 8 parts of Pericarpium Granatis, 20 parts on Flos Carthami, 0.1 part of Stigma Croci.
5. as the preparation method of claim 1-4 Chinese medicine composition as described in one of them, the method comprising the steps of:
(1) with above Herba Artemisiae, Radix Ginseng, the Radix Astragali, five tastes seed, Pericarpium Granati, Flos Carthami, Stigma Croci 7 flavor raw material of Chinese medicine, powder becomes coarse powder, adds in the extraction pot;
(2) add raw medicinal herbs quality 6-8 pure water doubly, open the automatic converter of vacuum, be decompressed to negative pressure 0.5-1MP, and be heated to and boil, keep slight boiling condition, carry out the economic benefits and social benefits concentrating return-flow, dynamic extraction 2-4 hour;
(3) collect extracting solution, extracting solution is evaporated to relative density 1.5-1.6;
(4) close heater, return to atmospheric pressure gradually;
(5) carry out spray drying, elder generation at 160 ℃ of preheating temperature 10-20 minutes, is set at 150-200 ℃ with inlet temperature with drying tower, and leaving air temp is set 50-100 ℃, pan feeding flow 1.2L/ branch;
(6) after whole the spray, continue to keep air intake after 5 minutes, open the discharge bucket discharging, obtain dry powder;
(7) dry powder is prepared into various dosage forms.
6. the preparation method of Chinese medicine composition according to claim 5 is characterized in that, the preparation method of described Chinese medicine composition oral liquid is:
Described dry powder with 100 times of pure water dilutions, is added orange juice, white sugar, brown sugar then, and adjust total amount embedding, sterilization, packing, namely get oral liquid.
7. the preparation method of Chinese medicine composition according to claim 5 is characterized in that, the preparation method of the powder of described Chinese medicine composition is:
(1) Herba Artemisiae is cut into 1 centimeter little disconnected, enter the drying chamber oven dry, when moisture content carries out crushing screening 10% the time, be advisable with the fineness that reaches the standard edible flour;
(2) Radix Astragali is cut into 1 centimeter little and breaks, enter the drying chamber oven dry, carry out crushing screening;
(3) the other drug composition is pulverized in the same way finish after, the multi-flavor medicine is combined, sieve then, reach multi-flavor medicine mix homogeneously, reach till the standard;
(4) laboratorian extracts specimen and detects, detect up to standard after, can enter the workshop pack, seal packing, sterilization.
8. the preparation method of Chinese medicine composition according to claim 7, it is characterized in that, in the preparation of the powder of described Chinese medicine composition, after pulverizing every Herba indigoferae Pseudotinctoriae, the medicine cleaning is clean, in order to avoid cause medicament mixed during Herba indigoferae Pseudotinctoriae under pulverizing, the ratio inequality influences drug effect or has side effects.
9. the preparation method of Chinese medicine composition according to claim 5 is characterized in that, the preparation method of described Chinese medicine composition solution is:
(1) Herba Artemisiae is cut into 1 centimeter and breaks, put into boiler and soaked 90 minutes, heat then;
(2) Radix Astragali is cut into 1 centimeter and breaks, when the temperature of Herba Artemisiae is raised to 90 ℃, after 40 minutes, the Radix Astragali is put into pot again, soaked 60 minutes;
(3) Pericarpium Granati be cut into 1 centimeter disconnected, when Radix Astragali temperature is upgraded to 90 ℃, through 35 minutes, Cortex cinnamomi japonici (Ramulus Cinnamomi) is put into boiler again, soaked 50 minutes;
(4) Radix Ginseng is cut into 1 centimeter section, soaked 10 minutes, Flos Carthami soaked 10 minutes;
(5) when the Pericarpium Granati temperature is upgraded to 90 ℃, Radix Ginseng after will soaking after 30 minutes, Flos Carthami is put into pot simultaneously, when treating that temperature is raised to 180 ℃, prolongs 30 minutes again, be down to 90 ℃ then, after treating 45 minutes, the laboratorian extracts specimen and detects, and fire is extinguished after up to standard, the medicine temperature reaches 45 to be pulled waste material out when spending, and carries out bottled operation then.
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| CN104887815A (en) * | 2015-06-25 | 2015-09-09 | 成都乾坤动物药业有限公司 | Compound traditional Chinese medicine for young animals, method for manufacturing compound traditional Chinese medicine and application thereof |
| CN113855749A (en) * | 2021-11-16 | 2021-12-31 | 林潘海 | Antiviral water condensation bead |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102160879A (en) * | 2010-02-23 | 2011-08-24 | 天津济世匙生物科技有限公司 | Submicron powder composition for preventing and treating poultry infectious diseases |
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| 王心喜: "中药万年蒿的化学成分与药理作用研究进展", 《中药材》, vol. 33, no. 5, 31 May 2010 (2010-05-31), pages 831 - 834 * |
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| CN104887815A (en) * | 2015-06-25 | 2015-09-09 | 成都乾坤动物药业有限公司 | Compound traditional Chinese medicine for young animals, method for manufacturing compound traditional Chinese medicine and application thereof |
| CN113855749A (en) * | 2021-11-16 | 2021-12-31 | 林潘海 | Antiviral water condensation bead |
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