CN102961526A - Compound proplis composition for treating urate deposition syndrome of broiler chicken and preparation method thereof - Google Patents
Compound proplis composition for treating urate deposition syndrome of broiler chicken and preparation method thereof Download PDFInfo
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- CN102961526A CN102961526A CN2012105162304A CN201210516230A CN102961526A CN 102961526 A CN102961526 A CN 102961526A CN 2012105162304 A CN2012105162304 A CN 2012105162304A CN 201210516230 A CN201210516230 A CN 201210516230A CN 102961526 A CN102961526 A CN 102961526A
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Abstract
The invention relates to a compound proplis composition for treating urate deposition syndrome of broiler chicken. The compound proplis composition is prepared by mixing the following components in parts by weight: 15-35 parts of propolis, 15-40 parts of rhizoma alismatis, 15-35 parts of myrobalan, 15-45 parts of poria, 15-35 parts of grifola, 15-35 parts of fructus forsythiae, 15-35 parts of akebia stem, 15-40 parts of astragalus, 15-35 parts of seaweed, 15-30 parts of dandelion and 15-35 parts of liquorice. The compound proplis composition has the beneficial effects that the formula is reasonable, preparation is simple, and the pure traditional Chinese medicine composition is pollution-free and obvious in curative effect, does not have toxic or side effect or drug residue and has a special effect of treating the urate deposition syndrome of broiler chicken according to the clinical verification.
Description
Technical field
The present invention relates to a kind of syndromic compound bee-glue composition of broiler urate deposition and preparation method thereof for the treatment of, belong to the animal field of medicaments, particularly a kind of syndromic compound bee-glue composition for the treatment of broiler urate deposition and preparation method thereof that is specifically designed to.
Background technology
It is the disease that is too much caused kidney injury by the urate deposition that virulence factor causes that the broiler urate deposition is levied, and is a kind of common disease that mainly betides broiler chicken.Primary disease is distributed widely in all over the world, with kidney swelling, pale, ureter swelling chap, in a large amount of urate deposition is arranged, it is feature that the organa parenchymatosum has a large amount of white urate deposition.This disease all can occur throughout the year, and mortality rate is between 10%-60%, and is very large to the harm of broiler chicken.It is relevant with factors such as heredity, anoxia, feedstuff and diseases that concrete inducement be it is generally acknowledged.
At present, this disease does not also have good Therapeutic Method, and just adding vitamin, electrolyte, antimicrobial drug etc. in feedstuff prevents and treats primary disease.Poultry is morbidity in a single day, and medicine is not treated effectively, already causes very large loss for broiler.
Therefore research and develop a kind of treat broiler ascites syndrome and have no side effect, the specific medicament of drug residue free is one of this field scientific research technical staff new problem anxious to be resolved.
Summary of the invention
The object of the invention is to overcome above-mentioned weak point, provide a kind of reasonable recipe, preparation simple, have no side effect, drug residue free, successful, effectively treat syndromic compound bee-glue composition of broiler urate deposition and preparation method thereof.
Implementation of the present invention is as follows for achieving the above object: a kind of syndromic compound bee-glue composition of broiler urate deposition for the treatment of, by following component by weight mixed preparing form: propolis 15-35 part, Rhizoma Alismatis 15-40 part, Fructus Chebulae 15-35 part, Poria 15-45 part, Polyporus 15-35 part, Fructus Forsythiae 15-35 part, Caulis Akebiae 15-35 part, Radix Astragali 15-40 part, Sargassum 15-35 part, Herba Taraxaci 15-30 part, Radix Glycyrrhizae 15-35 part.
Described various component optimum ratio amount is: 25 parts of propolis, 25 parts of Rhizoma Alismatis, 25 parts of Fructus Chebulaes, 30 parts in Poria, 25 parts of Polyporus, 25 parts of Fructus Forsythiaes, 25 parts of Caulis Akebiaes, 30 parts of the Radixs Astragali, 25 parts of Sargassums, 20 parts of Herba Taraxacis, 25 parts in Radix Glycyrrhizae.
A kind of preparation method for the treatment of the syndromic compound bee-glue composition of broiler urate deposition, carry out as follows:
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing by weight propolis 15-35 part, Rhizoma Alismatis 15-40 part, Fructus Chebulae 15-35 part, Poria 15-45 part, Polyporus 15-35 part, mix 5-10 minute to even;
(3) take by weighing by weight Fructus Forsythiae 15-35 part, Caulis Akebiae 15-35 part, Radix Astragali 15-40 part, Sargassum 15-35 part, Herba Taraxaci 15-30 part, Radix Glycyrrhizae 15-35 part, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
The medicinal property of each component is as follows:
Propolis: bitter, hot, cold, return spleen, lung, stomach warp, have anti-bacteria and anti-virus, antalgesic-antipruritic, promotion tissue regeneration, improve immunity, antiallergic oxidation, stop blooding, moisturize, the function of relieving cough and asthma, protection gastrointestinal mucosa etc.
Rhizoma Alismatis: sweet, light, cold, return kidney, urinary bladder channel, have the function of diuresis, clearing away damp-heat; Cure mainly dysuria, edema distension, diarrhea due to damp-heat etc.
The Fructus Chebulae: bitter, sour, puckery, flat, return lung, large intestine channel, the function of have astringing intestine to stop diarrhea, astringing the lung; Cure mainly the chronic diarrhea chronic dysentery, have blood in stool, proctoptosis, cough and asthma due to lung deficiency etc.
Poria: sweet, light, flat, return kidney, urinary bladder channel, have the function of inducing diuresis to remove edema; Cure mainly edema, dysuria etc.
Polyporus: sweet, light, flat, return kidney, urinary bladder channel, have the function of eliminating dampness and diuresis; Cure mainly dysuria, edema, have loose bowels, stranguria with turbid discharge, be with inferior.
Fructus Forsythiae: bitter, cold, return lung, the heart, small intestine meridian, have the function of heat-clearing and toxic substances removing, dispersing swelling and dissipating binds; Cure mainly epidemic febrile disease heating, skin ulcer general edema with yellowish skin poison etc.
Caulis Akebiae: bitter, be slightly cold, GUIXIN, small intestinal, urinary bladder channel have clearing away heat-fire, diuresis, a function of the stimulating milk secretion of stimulating the menstrual flow; Cure mainly aphtha of the mouth and tongue, dark coloured urine, five types of stranguria, edema, damp-heat vaginal discharge, galactostasis etc.
The Radix Astragali: sweet, tepor, return spleen, lung meridian, have the function of tonifying Qi and lifting yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, expelling pus and toxin by strengthening QI, expelling pus and promoting granulation; Curing mainly asthenia of pulmonosplenic qi, sinking of QI of middle-JIAO, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle sore difficultly bursts, bursts for a long time and do not hold back etc.
Sargassum: bitter, salty, cold, return liver, stomach, kidney channel, have the function of hard masses softening and resolving, inducing diuresis to remove edema; Cure mainly phlegm retention edema, painful and swollen testis etc.
Herba Taraxaci: bitter, sweet, cold, return liver, stomach warp, have the function of heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, inducing diuresis for treating stranguria syndrome; Cure mainly sore, lung abscess, pharyngalgia, jaundice due to damp-heat, pyretic stranguria etc.
Radix Glycyrrhizae: sweet, flat, return lung, the heart, spleen channel, have invigorating the spleen and replenishing QI, expelling phlegm for arresting cough and middle emergency, detoxifcation, coordinating the actions of various ingredients in a prescription, cushion toxicity, strong function; Cure mainly weakness of the spleen and stomach, cough with asthma, poisoning etc.
More than all flavor Chinese medicine according to the tcm theory compatible combination, for the syndromic paathogenic factor of broiler urate deposition and pathological change, the performance treating both the principal and secondary aspects of a disease effect.
The invention has the beneficial effects as follows: reasonable recipe, preparation is simple, and substep mixes more even; Pure Chinese medicine composition is pollution-free, no drug residue, and cost is low, and it is wide to draw materials, the curative effect highly significant.Theoretical and the modern Chinese medicine pharmacology theory according to the tradition Chinese veterinarian of motherland, optimize this 11 kinds of medicines, and make them form pure Chinese powder medicine according to optimum ratio, clinical practice proves, to treatment broiler urate deposition syndrome specially good effect is arranged and have no side effect, drug residue free and drug resistance.And make poultry product reach nuisanceless requirement, satisfy the export standard of poultry product, guaranteed that effectively people's is healthy.
The specific embodiment
Below in conjunction with preferred embodiment, to details are as follows according to the specific embodiment provided by the invention:
Embodiment 1
A kind of syndromic compound bee-glue composition of broiler urate deposition and preparation method thereof for the treatment of: carry out as follows: (every part by 10g)
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing by weight 150 parts of propolis, 150 parts of Rhizoma Alismatis, 150 parts of Fructus Chebulaes, 150 parts in Poria, 150 parts of Polyporus, mix 5-10 minute to even;
(3) take by weighing by weight 150 parts of Fructus Forsythiaes, 150 parts of Caulis Akebiaes, 150 parts of the Radixs Astragali, 150 parts of Sargassums, 150 parts of Herba Taraxacis, 150 parts in Radix Glycyrrhizae, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Embodiment 2
A kind of syndromic compound bee-glue composition of broiler urate deposition and preparation method thereof for the treatment of: carry out as follows: (every part by 10g)
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing by weight 250 parts of propolis, 250 parts of Rhizoma Alismatis, 250 parts of Fructus Chebulaes, 250 parts in Poria, 250 parts of Polyporus, mix 5-10 minute to even;
(3) take by weighing by weight 250 parts of Fructus Forsythiaes, 250 parts of Caulis Akebiaes, 250 parts of the Radixs Astragali, 250 parts of Sargassums, 250 parts of Herba Taraxacis, 250 parts in Radix Glycyrrhizae, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Embodiment 3
A kind of syndromic compound bee-glue composition of broiler urate deposition and preparation method thereof for the treatment of: carry out as follows: (every part by 10g)
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing by weight 350 parts of propolis, 400 parts of Rhizoma Alismatis, 350 parts of Fructus Chebulaes, 450 parts in Poria, 350 parts of Polyporus, mix 5-10 minute to even;
(3) take by weighing by weight 350 parts of Fructus Forsythiaes, 350 parts of Caulis Akebiaes, 400 parts of the Radixs Astragali, 350 parts of Sargassums, 300 parts of Herba Taraxacis, 350 parts in Radix Glycyrrhizae, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Clinical trial:
The clinical experiment animal selects 20 ages in days, body weight at 1.0kg-1.1kg, and Laboratory Diagnosed is the syndromic ill broiler of broiler urate deposition.Ill chicken isolation is raised separately, the complete feed of feeding, and be divided at random 3 groups, and 60 every group, 3 groups of feeding environments are identical, and experimental period was carried out 5 days altogether; The blank group is left intact, and the medicine matched group uses treatment with institute's control drug by its description; Chinese medicine composition group of the present invention can be with product of the present invention (embodiment of the invention 1 prepared compositions) the ill poultry of feeding, and a day dose is: per 100 restrain 220 kilograms of present composition spices feeds or drinks water 400 kilograms, every day 1-2 time; Reach the purpose for the treatment of disease after oral by gastrointestinal absorption.Computational methods: mortality rate=dead animal number/experimental animal number * 100%, cure rate=healing number of animals/experimental animal number * 100%.Result's (testing the 5th day) when following table is the experiment end.
Table is the present invention and the syndromic situation contrast of other medicines treatment broiler urate deposition:
| Numbering | Group | Mortality rate % | Cure rate % | Symptom rate % is arranged during end |
| I | The blank group | 20.0 | 63.3 | 16.7 |
| II | The BAZHENG SAN group | 10.0 | 80.0 | 10.0 |
| III | Chinese medicine composition group of the present invention | 5.0 | 90.0 | 5.0 |
This clinical effectiveness statistical analysis, present composition group is being compared difference extremely significantly (P＜0.01) with the BAZHENG SAN group aspect the cure rate.
Safety testing:
Choose 60 of 20 age in days healthy AA broiler, according to 10 times of spices of the embodiment of the invention 1 made Chinese medicine composition recommended dose or drank water 5 days, during the medication, healthy chicken is without any bad or Deviant Behavior performance, the drinking-water of searching for food is normal, and body weight increases that to compare difference not remarkable with blank group (being not administration of health group).
Above-mentioned detailed description of syndromic compound bee-glue composition of this treatment broiler urate deposition and preparation method thereof being carried out with reference to embodiment; illustrative rather than determinate; can list several embodiment according to institute's limited range; therefore in the variation and the modification that do not break away under the general plotting of the present invention, should belong within protection scope of the present invention.
Claims (3)
1. treatment broiler urate deposition syndromic compound bee-glue composition, it is characterized in that by following component by weight mixed preparing form: propolis 15-35 part, Rhizoma Alismatis 15-40 part, Fructus Chebulae 15-35 part, Poria 15-45 part, Polyporus 15-35 part, Fructus Forsythiae 15-35 part, Caulis Akebiae 15-35 part, Radix Astragali 15-40 part, Sargassum 15-35 part, Herba Taraxaci 15-30 part, Radix Glycyrrhizae 15-35 part.
2. the syndromic compound bee-glue composition for the treatment of broiler urate deposition according to claim 1, it is characterized in that by following component by weight mixed preparing form: 25 parts of propolis, 25 parts of Rhizoma Alismatis, 25 parts of Fructus Chebulaes, 30 parts in Poria, 25 parts of Polyporus, 25 parts of Fructus Forsythiaes, 25 parts of Caulis Akebiaes, 30 parts of the Radixs Astragali, 25 parts of Sargassums, 20 parts of Herba Taraxacis, 25 parts in Radix Glycyrrhizae.
3. the preparation method of the syndromic compound bee-glue composition for the treatment of broiler urate deposition according to claim 1 and 2 is characterized in that carrying out as follows:
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing by weight propolis 15-35 part, Rhizoma Alismatis 15-40 part, Fructus Chebulae 15-35 part, Poria 15-45 part, Polyporus 15-35 part, mix 5-10 minute to even;
(3) take by weighing by weight Fructus Forsythiae 15-35 part, Caulis Akebiae 15-35 part, Radix Astragali 15-40 part, Sargassum 15-35 part, Herba Taraxaci 15-30 part, Radix Glycyrrhizae 15-35 part, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
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| CN201210516230.4A CN102961526B (en) | 2012-11-22 | 2012-11-22 | Syndromic compound bee-glue composition for the treatment of broiler urate deposition and preparation method thereof |
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Cited By (3)
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| CN103505577A (en) * | 2013-09-03 | 2014-01-15 | 邵友德 | Traditional Chinese medicine composition for treating chicken kidney swelling and piebald kidney |
| CN103598432A (en) * | 2013-10-14 | 2014-02-26 | 当涂县湖阳兴旺园养猪场 | Feed capable of improving meat quality of broilers, and preparation method thereof |
| CN113694102A (en) * | 2021-10-11 | 2021-11-26 | 苏州科牧生物技术有限公司 | Preparation method of traditional Chinese medicine additive for solving urate deposition of livestock and poultry |
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Cited By (5)
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| CN103505577A (en) * | 2013-09-03 | 2014-01-15 | 邵友德 | Traditional Chinese medicine composition for treating chicken kidney swelling and piebald kidney |
| CN103505577B (en) * | 2013-09-03 | 2016-05-11 | 邵友德 | A kind ofly treat that chicken kidney is swollen, the Chinese medicine composition of piebald kidney |
| CN103598432A (en) * | 2013-10-14 | 2014-02-26 | 当涂县湖阳兴旺园养猪场 | Feed capable of improving meat quality of broilers, and preparation method thereof |
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| CN113694102A (en) * | 2021-10-11 | 2021-11-26 | 苏州科牧生物技术有限公司 | Preparation method of traditional Chinese medicine additive for solving urate deposition of livestock and poultry |
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