CN102670863A - Compound propolis composition for treating acariasis of domestic animal and preparation method thereof - Google Patents
Compound propolis composition for treating acariasis of domestic animal and preparation method thereof Download PDFInfo
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- CN102670863A CN102670863A CN201210144949XA CN201210144949A CN102670863A CN 102670863 A CN102670863 A CN 102670863A CN 201210144949X A CN201210144949X A CN 201210144949XA CN 201210144949 A CN201210144949 A CN 201210144949A CN 102670863 A CN102670863 A CN 102670863A
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Abstract
The invention relates to a compound propolis composition for treating acariasis of domestic animal and a preparation method thereof. The composition is prepared from the following components in part by weight: 15 to 35 parts of propolis, 15 to 35 parts of sulfur, 10 to 35 parts of realgar, 15 to 40 parts of dried alum, 15 to 35 parts of rhubarb, 10 to 35 parts of natural indigo, 10 to 35 parts of borneol and 15 to 35 parts of Japanese ampelopsis root. The invention has the advantages that the composition is reasonable in formula, simple in preparation, environmental-friendly, high in bioavailability due to superfine grinding, and obvious in curative effect, and does not have toxic or side effect, medicine residues and medicine resistance are avoided, and clinical results prove that the composition has a special effect on acariasis of domestic animal.
Description
Technical field
The present invention relates to compound bee-glue composition of treating acariasis of domestic animal and preparation method thereof, belong to the animal field of medicaments, particularly a kind of compound bee-glue composition that is specifically designed to the treatment acariasis of domestic animal and preparation method thereof.
Background technology
Acariasis of domestic animal is a kind of height contagious infection dermatoses that is caused by acaricide, is characteristic with itch all over and affected part depilation.This disease of animal infection symptom, bodies such as play is itched, depilation often occur and becomes thin, influences growth promoter gradually, more do not cause death for a long time, causes very large economy loss to animal raising.
The traditional Chinese medical science thinks that this disease belongs to exopathogen invading into the interior, the damp and hot skin of fighting mutually, due to QI and blood is weak, treatment should adopt heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, antipruritic except that wind, removing heat from blood dehumidifies, the principle of strengthening vital QI to eliminate pathogenic factors.Primary disease sickness rate and case fatality rate are all very high, all can take place throughout the year, are one of principal diseases of harm livestock culturing industry.
This disease almost spreads all over all livestock culturing countries of the world, distributes very extensively.At present, treat this disease the most frequently used be Chinese medicine and Western medicine, Chinese medicine is because its prescription is unreasonable or just simple the pulverizing, and particle diameter is excessive, and drug release is slower, causes its bioavailability lower, clinical effectiveness is not fine; And western medical treatment is main with antibacterial, antiinflammatory etc. mainly, and Western medicine produces problems such as drug resistance and drug residue owing to its toxic and side effects is strong, easy, and clinical practice is very limited.
Therefore research and develop that a kind of to treat the having no side effect of acariasis of domestic animal, drug residue free, the specific medicament that produces that has no drug resistance be one of this field scientific research technical staff new problem anxious to be solved.
Summary of the invention
The objective of the invention is to overcome above-mentioned weak point, provide that a kind of reasonable recipe, preparation are simple, micronizing, bioavailability are high, effect obviously, have no side effect, have no drug resistance and the compound bee-glue composition of effective treatment acariasis of domestic animal of drug residue and preparation method thereof.
Following for realizing the embodiment that above-mentioned purpose the present invention adopted: a kind of compound bee-glue composition of treating acariasis of domestic animal, by following component by weight mixed preparing form: propolis 15-35 part, sulfur 15-35 part, Realgar 10-35 part, dried Alumen 15-40 part, Radix Et Rhizoma Rhei 15-35 part, Indigo Naturalis 10-35 part, Borneolum Syntheticum 10-35 part, Radix Ampelopsis 15-35 part.
On the basis of such scheme, said various component optimum ratio amounts are: 25 parts of propolis, 25 parts in sulfur, 20 parts of Realgars, 30 parts of dried Alumens, 25 parts of Radix Et Rhizoma Rhei, 20 parts of Indigo Naturaliss, 20 parts of Borneolum Syntheticums, 25 parts of Radix Ampelopsis.
A kind of method for preparing of treating the compound bee-glue composition of acariasis of domestic animal, carry out as follows:
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing propolis 15-35 part, sulfur 15-35 part, Realgar 10-35 part, dried Alumen 15-40 part by weight, mix 5-10 minute to even;
(3) take by weighing Radix Et Rhizoma Rhei 15-35 part, Indigo Naturalis 10-35 part, Borneolum Syntheticum 10-35 part, Radix Ampelopsis 15-35 part by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
The medicinal property of each component is following:
Propolis: bitter, hot, cold, return spleen, lung, stomach warp, have anti-bacteria and anti-virus, antalgesic-antipruritic, promotion tissue regeneration, improve immunity, antiallergic oxidation, stop blooding, moisturize, the function of relieving cough and asthma, protection gastrointestinal mucosa.
Sulfur: acid, temperature, poisonous, return kidney, large intestine channel, have and mend function fiery supporing yang, relieving constipation; Cure mainly yang deficiency constipation, deficiency and coldness asthma, scabies, carbuncle of yin nature malignant boil etc.
Realgar: hot, temperature, poisonous, return liver, large intestine channel, have the function of detoxifcation parasite killing, removing dampness and eliminating phlegm; Cure mainly carbuncle sore tumefacting virus, abdominal pain due to worm stagnation, infantile convulsion, scabies etc.
Dried Alumen: cold, acid, puckery, return lung, spleen, large intestine, Liver Channel, have heat clearing away expectorant, hemostasis antidiarrheal, dampness removing to stop itchin, the parasiticidal function of detoxifcation; Cure mainly incessant chronic diarrhea, heavily wait after having blood in stool, let out dysentery.
Radix Et Rhizoma Rhei: bitter, cold, return spleen, stomach, large intestine, liver, pericardium channel, have the function of purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, removing mass clots absorbing; Cure mainly excess-heat constipation, combined symptoms, the yellow furunculosis of skin ulcer, conjunctival congestion and swelling pain etc.
Indigo Naturalis: salty, cold, return Liver Channel, have the function of heat-clearing and toxic substances removing, blood cooling and ecchymoses removing; Cure mainly that pyretic toxicity is sent out speckle, heat in blood is told nosebleed, hot carbuncle sore, laryngopharynx swelling and pain, aphtha of the mouth and tongue etc.
Borneolum Syntheticum: hot, bitter, be slightly cold, GUIXIN, spleen, lung meridian have the function of heat-clearing and fire-dispersing, sensible refreshment, reducing swelling and alleviating pain; Cure mainly heat in the heart tongue boil, conjunctival congestion cataracta, sore swollen toxin, coma convulsions, laryngopharynx swelling and pain etc.
Radix Ampelopsis: bitter, cold, GUIXIN, stomach warp have the function of heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, expelling pus and promoting granulation; Cure mainly that hematodiarrhoea is had blood in stool, sore, carbuncle and painful swelling, burn, scald etc.
More than all flavor Chinese medicine according to the Chinese medical theory compatible combination, to the paathogenic factor and the clinical symptoms of acariasis of domestic animal, the effect of performance treating both the principal and secondary aspects of a disease.
The invention has the beneficial effects as follows: reasonable recipe, preparation is simple, and substep mixes more even; Chinese medicine composition is pollution-free, have no side effect, no drug residue, have no drug resistance, and cost is low, and it is wide to draw materials, and micronizing, bioavailability are high, the curative effect highly significant.The present invention optimizes this eight flavors Chinese medicine, and makes them form pure Chinese powder medicine according to optimum ratio according to Chinese veterinarian's traditional theory, and clinical practice proves that the treatment acariasis of domestic animal is had specially good effect.
The specific embodiment
Below in conjunction with preferred embodiment, to details are as follows according to the specific embodiment provided by the invention:
Embodiment 1
A kind of compound bee-glue composition of treating acariasis of domestic animal and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing 150 parts of propolis, 150 parts in sulfur, 100 parts of Realgars, 150 parts of dried Alumens by weight, mix 5-10 minute to even;
(3) take by weighing 150 parts of Radix Et Rhizoma Rhei, 100 parts of Indigo Naturaliss, 100 parts of Borneolum Syntheticums, 150 parts of Radix Ampelopsis by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Embodiment 2
A kind of compound bee-glue composition of treating acariasis of domestic animal and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing 250 parts of propolis, 250 parts in sulfur, 150 parts of Realgars, 250 parts of dried Alumens by weight, mix 5-10 minute to even;
(3) take by weighing 250 parts of Radix Et Rhizoma Rhei, 200 parts of Indigo Naturaliss, 200 parts of Borneolum Syntheticums, 250 parts of Radix Ampelopsis by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Embodiment 3
A kind of compound bee-glue composition of treating acariasis of domestic animal and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing 350 parts of propolis, 350 parts in sulfur, 350 parts of Realgars, 400 parts of dried Alumens by weight, mix 5-10 minute to even;
(3) take by weighing 350 parts of Radix Et Rhizoma Rhei, 350 parts of Indigo Naturaliss, 350 parts of Borneolum Syntheticums, 350 parts of Radix Ampelopsis by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Clinical trial:
The clinical experiment animal selects for use 100-180 age in days, body weight at 25kg-55kg, and laboratory is diagnosed as the ill sheep of supporting mange and scab.Ill sheep is isolated raising separately, the complete feed of feeding, and be divided into 3 groups at random, 20 every group, 3 groups of feeding environments are identical, experimental period 8 days; The blank group is left intact, and the medicine matched group uses treatment with " wiping scabies looses " by specification; Chinese medicine composition group of the present invention is applied to the affected part after can product of the present invention being in harmonious proportion so that soybean oil is an amount of, once a day.Logotype 5-7 days.
Table is the field applicable cases contrast that mange and scab is supported in the present invention and other medicines treatment:
| Numbering | Group | Case fatality rate % | Cure rate % | Symptom rate % is arranged during end |
| I | The blank group | 13.9 | 57.6 | 28.5 |
| II | Wipe the diffusing group of scabies | 6.8 | 80.3 | 12.9 |
| III | Present composition group | 2.6 | 90.4 | 7.0 |
This clinical effectiveness is through statistical analysis, and present composition treatment group is loose to organize with the wiping scabies and compared difference extremely significantly (P＜0.01) aspect the cure rate.
Above-mentioned detailed description of compound bee-glue composition of this treatment acariasis of domestic animal and preparation method thereof being carried out with reference to embodiment; Be illustrative rather than determinate; Can enumerate out several embodiment according to institute's limited range; Therefore in the variation and the modification that do not break away under the general plotting of the present invention, should belong within protection scope of the present invention.
Claims (3)
1. compound bee-glue composition of treating acariasis of domestic animal, it is characterized in that by following component by weight mixed preparing form: propolis 15-35 part, sulfur 15-35 part, Realgar 10-35 part, dried Alumen 15-40 part, Radix Et Rhizoma Rhei 15-35 part, Indigo Naturalis 10-35 part, Borneolum Syntheticum 10-35 part, Radix Ampelopsis 15-35 part.
2. the compound bee-glue composition of treatment acariasis of domestic animal according to claim 1, it is characterized in that by following component by weight mixed preparing form: 25 parts of propolis, 25 parts in sulfur, 20 parts of Realgars, 30 parts of dried Alumens, 25 parts of Radix Et Rhizoma Rhei, 20 parts of Indigo Naturaliss, 20 parts of Borneolum Syntheticums, 25 parts of Radix Ampelopsis.
3. the method for preparing of the compound bee-glue composition of a treatment acariasis of domestic animal according to claim 1 and 2 is characterized in that carrying out as follows:
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing propolis 15-35 part, sulfur 15-35 part, Realgar 10-35 part, dried Alumen 15-40 part by weight, mix 5-10 minute to even;
(3) take by weighing Radix Et Rhizoma Rhei 15-35 part, Indigo Naturalis 10-35 part, Borneolum Syntheticum 10-35 part, Radix Ampelopsis 15-35 part by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
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| CN201210144949.XA CN102670863B (en) | 2012-05-11 | 2012-05-11 | Compound propolis composition for treating acariasis of domestic animal and preparation method thereof |
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| CN201210144949.XA CN102670863B (en) | 2012-05-11 | 2012-05-11 | Compound propolis composition for treating acariasis of domestic animal and preparation method thereof |
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| CN102670863A true CN102670863A (en) | 2012-09-19 |
| CN102670863B CN102670863B (en) | 2014-01-01 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103877326A (en) * | 2014-03-15 | 2014-06-25 | 青岛绿曼生物工程有限公司 | Traditional Chinese medicine composition for treating acariasis of domestic animals and preparation method thereof |
| CN105998643A (en) * | 2016-05-30 | 2016-10-12 | 青岛海之源智能技术有限公司 | Compound traditional Chinese medicinal spray for preventing and treating mink scab and preparation method of compound traditional Chinese medicinal spray |
Citations (2)
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| CN101648002A (en) * | 2008-08-13 | 2010-02-17 | 北京和润创新医药科技发展有限公司 | Medicinal composition for treating skin injury and ulcer and application thereof |
| CN102362951A (en) * | 2011-10-25 | 2012-02-29 | 李安明 | Traditional Chinese medicine for treating psoriasis |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101648002A (en) * | 2008-08-13 | 2010-02-17 | 北京和润创新医药科技发展有限公司 | Medicinal composition for treating skin injury and ulcer and application thereof |
| CN102362951A (en) * | 2011-10-25 | 2012-02-29 | 李安明 | Traditional Chinese medicine for treating psoriasis |
Non-Patent Citations (3)
| Title |
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| 刘汉章: "蜂产品在治疗畜病中的应用技术", 《农技服务》 * |
| 宋兆友: "常用皮肤病中药外用制剂介绍", 《皮肤病与性病》 * |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103877326A (en) * | 2014-03-15 | 2014-06-25 | 青岛绿曼生物工程有限公司 | Traditional Chinese medicine composition for treating acariasis of domestic animals and preparation method thereof |
| CN105998643A (en) * | 2016-05-30 | 2016-10-12 | 青岛海之源智能技术有限公司 | Compound traditional Chinese medicinal spray for preventing and treating mink scab and preparation method of compound traditional Chinese medicinal spray |
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| CN102670863B (en) | 2014-01-01 |
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Granted publication date: 20140101 Termination date: 20160511 |