CN102283889A - Pure Chinese medicinal composition for treating duck virus hepatitis and preparation method thereof - Google Patents

Abstract

The invention discloses a pure Chinese medicinal composition for treating duck virus hepatitis and a preparation method thereof, which relate to a pure Chinese medicinal composition for a poultry medicine and a preparation method thereof. The preparation method of the pure Chinese medicinal composition for treating duck virus hepatitis comprises the following steps of: firstly, weighing 15-25 parts of propolis, 10-20 parts of capillary wormwood herb, 15-25 parts of radix bupleuri and 15-25 parts of redroot gromwell which are micronized and pass through a sieve with 500 meshes according to the weight and mixing for 5-10 minutes to be uniform; secondly, weighing 10-20 parts of gentiana, 10-20 parts of liquorice, 20-35 parts of indigowoad root, and 10-20 parts of mung bean and mixing for 5-10 minutes to be uniform; and thirdly, combining compositions obtained in the first step and the second step, continuously mixing for 10-15 minutes to be uniform. The pure Chinese medicinal composition has the beneficial effects of reasonable composition, simpleness in preparation, no toxic and side effect, no pollution, no medicine residue, no medicine resistance, micronization, high bioavailability, remarkable curative effects and special effect for treating the duck virus hepatitis by clinical tests.

Description

A kind of pure Chinese medicine composition for the treatment of duck viral hepatitis and preparation method thereof

Technical field

The present invention relates to pure Chinese medicine composition for the treatment of duck viral hepatitis and preparation method thereof, belong to the animal field of medicaments, particularly a kind of pure Chinese medicine composition that is specifically designed to the treatment duck viral hepatitis and preparation method thereof.

Background technology

Duck viral hepatitis is a kind of common acute, the height lethal infectious disease that is caused by DHV, mainly infected for 2 ages in week with interior duckling, being mulberry with opisthotonus, beak end and pawl point congestion clinically is feature, cut open the visible liver enlargement of inspection and a large amount of hemorrhagic speckles is arranged, mortality rate is very high, is that one of duck principal disease is already supported in harm.

The pathogen of primary disease is a DHV, and this disease spreads all over more or less a hundred country of five continents, and it is very extensive to distribute.At present, treat this disease the most frequently used be Chinese medicine and antiviral Western medicine, Chinese medicine is because its prescription is unreasonable or just simple the pulverizing, and particle diameter is excessive, and drug release is slower, causes its bioavailability lower, clinical effectiveness is not fine; And various antiviral Western medicine such as ribavirin, amantadine etc., the Ministry of Agriculture bans use of.

Therefore researching and developing a kind of specific medicament for the treatment of duck viral hepatitis is one of this field scientific research technical staff new problem anxious to be solved.

Summary of the invention

The objective of the invention is to overcome above-mentioned weak point, provide that a kind of reasonable recipe, preparation are simple, micronizing, bioavailability height, effect obviously, have no drug resistance and the pure Chinese medicine composition of effective treatment duck viral hepatitis of toxic and side effects and preparation method thereof.

Implementation of the present invention is as follows for achieving the above object: a kind of pure Chinese medicine composition for the treatment of duck viral hepatitis, by following component by weight mixed preparing form: propolis 15-25 part, Herba Artemisiae Scopariae 10-20 part, Radix Bupleuri 15-25 part, Radix Arnebiae (Radix Lithospermi) 15-25 part, Radix Gentianae 10-20 part, Radix Glycyrrhizae 10-20 part, Radix Isatidis 20-35 part, Semen phaseoli radiati 10-20 part.

Described various component optimum ratio amount is: 20 parts of propolis, 15 parts of Herba Artemisiae Scopariaes, 20 parts of Radix Bupleuri, 20 parts of Radix Arnebiae (Radix Lithospermi)s, 15 parts of Radix Gentianae, 15 parts in Radix Glycyrrhizae, 30 parts of Radix Isatidis, 15 parts in Semen phaseoli radiati.

A kind of preparation method for the treatment of the pure Chinese medicine composition of duck viral hepatitis, carry out as follows:

(1) the various compositions in the prescription is crossed 500 mesh sieves after the micronizing respectively;

(2) take by weighing propolis 15-25 part, Herba Artemisiae Scopariae 10-20 part, Radix Bupleuri 15-25 part, Radix Arnebiae (Radix Lithospermi) 15-25 part by weight, mix 5-10 minute to even;

(3) take by weighing Radix Gentianae 10-20 part, Radix Glycyrrhizae 10-20 part, Radix Isatidis 20-35 part, Semen phaseoli radiati 10-20 part by weight, mix 5-10 minute to even;

(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.

The medicinal property of each component is as follows:

Propolis: bitter, hot, cold, return spleen, stomach warp, have the function of anti-inflammation, antalgesic-antipruritic, promotion tissue regeneration, raising immunity, antiallergic oxidation, hemostasis, protection gastrointestinal mucosa.

Herba Artemisiae Scopariae: be slightly cold, bitter, hot, return liver, stomach, spleen, gallbladder meridian, have the function of eliminating damp-heat, promoting the function of the gallbladder to alleviate jaundice; Cure mainly jaundice, oliguria, eczema pruritus.

Radix Arnebiae (Radix Lithospermi): sweet, salty, cold, return liver, heart channel, have the function of removing heat from blood and promoting blood circulation, detoxifcation speckle removing; Cure mainly heat in blood poison Sheng, pyretic toxicity ecchymosis, eczema etc.

Radix Bupleuri: hot, bitter, be slightly cold, return liver, gallbladder, lung meridian, have the function of delivering with lining, elevate a turnable ladder yang-energy, dispersing the stagnated live-QI to relieve the stagnation of QI; Cure mainly cold, fever, alternate attack of chill and fever, insufficiency of the spleen chronic diarrhea, proctoptosis.

Radix Gentianae: bitter, cold, return liver, gallbladder meridian, have eliminating pathogen in the liver gallbladder excess-fire, remove the function of damp-heat in lower-JIAO; Cure mainly jaundice due to damp-heat, conjunctival congestion and swelling pain, eczema pruritus.

Radix Glycyrrhizae: sweet, flat, return lung, the heart, spleen channel, have invigorating the spleen and replenishing QI, expelling phlegm for arresting cough and middle emergency, detoxifcation, coordinating the actions of various ingredients in a prescription, cushion toxicity, strong function; Cure mainly weakness of the spleen and stomach, cough with asthma, poisoning.

Radix Isatidis: bitter, cold, GUIXIN, stomach warp have the function of removing heat from blood sore-throat relieving, heat-clearing and toxic substances removing; Cure mainly laryngopharynx swelling and pain, aphtha of the mouth and tongue, skin ulcer general edema with yellowish skin poison, maculae caused by violent heat pathogen.

Semen phaseoli radiati: sweet, cool, GUIXIN, stomach warp, the function that has heat-clearing and toxic substances removing, relieves summer heat and be good for the stomach; Cure mainly diarrhea due to damp-heat, the detoxifcation protect the liver, antiallergic.

More than all flavor Chinese medicine according to the Chinese medical theory compatible combination, at pathogenic microorganism, clinical symptoms and the pathological change of duck viral hepatitis, the performance treating both the principal and secondary aspects of a disease effect.

The invention has the beneficial effects as follows: reasonable recipe, preparation is simple, and substep mixes more even; Pure Chinese medicine composition is pollution-free, no drug residue, have no drug resistance, and cost is low, and it is wide to draw materials, micronizing, bioavailability height, curative effect highly significant.The present invention is according to Chinese veterinarian's traditional theory, optimize this eight flavors Chinese medicine, and make them form pure Chinese powder medicine according to optimum ratio, clinical practice proves, the treatment duck viral hepatitis there is specially good effect, and make its product meat reach nuisanceless requirement, satisfy the export standard of product, guaranteed that effectively people's is healthy.

The specific embodiment

Below in conjunction with preferred embodiment, to details are as follows according to the specific embodiment provided by the invention:

Embodiment 1

A kind of pure Chinese medicine composition for the treatment of duck viral hepatitis and preparation method thereof: carry out as follows: (every part by 10g)

(1) the various compositions in the prescription is crossed 500 mesh sieves after the micronizing respectively;

(2) take by weighing 150 parts of propolis, 100 parts of Herba Artemisiae Scopariaes, 150 parts of Radix Bupleuri, 150 parts of Radix Arnebiae (Radix Lithospermi)s by weight, mix 5-10 minute to even;

(3) take by weighing 100 parts of Radix Gentianae, 100 parts in Radix Glycyrrhizae, 200 parts of Radix Isatidis, 100 parts in Semen phaseoli radiati by weight, mix 5-10 minute to even;

(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.

Embodiment 2

A kind of pure Chinese medicine composition for the treatment of duck viral hepatitis and preparation method thereof: carry out as follows: (every part by 10g)

(1) the various compositions in the prescription is crossed 500 mesh sieves after the micronizing respectively;

(2) take by weighing 200 parts of propolis, 150 parts of Herba Artemisiae Scopariaes, 200 parts of Radix Bupleuri, 200 parts of Radix Arnebiae (Radix Lithospermi)s by weight, mix 5-10 minute to even;

(3) take by weighing 150 parts of Radix Gentianae, 150 parts in Radix Glycyrrhizae, 300 parts of Radix Isatidis, 150 parts in Semen phaseoli radiati by weight, mix 5-10 minute to even;

(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.

Embodiment 3

A kind of pure Chinese medicine composition for the treatment of duck viral hepatitis and preparation method thereof: carry out as follows: (every part by 10g)

(1) the various compositions in the prescription is crossed 500 mesh sieves after the micronizing respectively;

(2) take by weighing 250 parts of propolis, 200 parts of Herba Artemisiae Scopariaes, 250 parts of Radix Bupleuri, 250 parts of Radix Arnebiae (Radix Lithospermi)s by weight, mix 5-10 minute to even;

(3) take by weighing 200 parts of Radix Gentianae, 200 parts in Radix Glycyrrhizae, 350 parts of Radix Isatidis, 200 parts in Semen phaseoli radiati by weight, mix 5-10 minute to even;

(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.

Clinical trial:

With the ill duck of product feeding of the present invention etc., a day dose is: by the every 100g of the present invention, spice 200kg feeds, drinking-water 500kg, every day 2-3 time, logotype 3-5 day; Oral back reaches the purpose of treatment disease by gastrointestinal absorption.

Table is the field applicable cases contrast of the present invention and other medicines treatment duck viral hepatitis:

Compile	Group	Dead	Cure	Symptom is arranged during end
					I	The blank group	31.5	48.2	20.3
II	Duck poison health is loose and is organized	11.2	74.2	14.6
					III	Hepatitis recovery oral liquid group	9.9	78.6	11.5
IV	Chinese medicine composition of the present invention	7.5	84.7	7.8

This clinical effectiveness is analyzed by statistics, and present composition treatment group is being compared difference all extremely significantly (P＜0.01) and significantly (P＜0.05) with the diffusing group of duck poison health, hepatitis recovery oral liquid group aspect the cure rate.

Above-mentioned detailed description of pure Chinese medicine composition of this treatment duck viral hepatitis and preparation method thereof being carried out with reference to embodiment; be illustrative rather than determinate; can list several embodiment according to institute's limited range; therefore in the variation and the modification that do not break away under the general plotting of the present invention, should belong within protection scope of the present invention.

Claims (3)

1. pure Chinese medicine composition for the treatment of duck viral hepatitis, it is characterized in that by following component by weight mixed preparing form: propolis 15-25 part, Herba Artemisiae Scopariae 10-20 part, Radix Bupleuri 15-25 part, Radix Arnebiae (Radix Lithospermi) 15-25 part, Radix Gentianae 10-20 part, Radix Glycyrrhizae 10-20 part, Radix Isatidis 20-35 part, Semen phaseoli radiati 10-20 part.

2. a kind of pure Chinese medicine composition for the treatment of duck viral hepatitis according to claim 1 is characterized in that described various component optimum ratio amount is: 20 parts of propolis, 15 parts of Herba Artemisiae Scopariaes, 20 parts of Radix Bupleuri, 20 parts of Radix Arnebiae (Radix Lithospermi)s, 15 parts of Radix Gentianae, 15 parts in Radix Glycyrrhizae, 30 parts of Radix Isatidis, 15 parts in Semen phaseoli radiati.

3. the preparation method of the pure Chinese medicine composition of a treatment duck viral hepatitis according to claim 1 is characterized in that carrying out as follows:

(1) the various compositions in the prescription is crossed 500 mesh sieves after the micronizing respectively;

(2) take by weighing propolis 15-25 part, Herba Artemisiae Scopariae 10-20 part, Radix Bupleuri 15-25 part, Radix Arnebiae (Radix Lithospermi) 15-25 part by weight, mix 5-10 minute to even;

(3) take by weighing Radix Gentianae 10-20 part, Radix Glycyrrhizae 10-20 part, Radix Isatidis 20-35 part, Semen phaseoli radiati 10-20 part by weight, mix 5-10 minute to even;

(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.