CN102579593B - Pure Chinese medicinal composition for treating infectious bursal disease, newcastle disease, duck virus hepatitis and other viral diseases, as well as preparation method thereof - Google Patents
Pure Chinese medicinal composition for treating infectious bursal disease, newcastle disease, duck virus hepatitis and other viral diseases, as well as preparation method thereof Download PDFInfo
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Abstract
The invention relates to a pure Chinese medicinal composition for treating infectious bursal disease, newcastle disease, duck virus hepatitis and other viral diseases. The pure Chinese medicinal composition is prepared by mixing the following components in parts by weight: 15 to 35 parts of indigowoad root, 15 to 25 parts of weeping forsythiae capsule, 15 to 35 parts of Chinese thorowax root, 15 to 30 parts of Chinese mugwort leaf, 15 to 30 parts of Chinese atractylode rhizome, 15 to 40 parts of dyer woad leaf, 10 to 35 parts of liquorice, and 15 to 35 parts of capillary wormwood herb. The pure Chinese medicinal composition has the beneficial effects of reasonable prescription, simpleness in preparation, no toxic or side effect, no pollution, no medicament residues, no drug resistance, convenience for ignition and smoking, all-pervasive smoke generated by ignition, comprehensive and complete disinfection control and remarkable curative effect. Clinical application proves that: the pure Chinese medicinal composition has special effect in treating the infectious bursal disease, newcastle disease, duck virus hepatitis and other viral diseases.
Description
Technical field
The present invention relates to pure Chinese medicine composition for the treatment of the viral diseases such as infectious bursal disease, newcastle, duck viral hepatitis and preparation method thereof, belong to animal field of medicaments, particularly a kind of pure Chinese medicine composition that is specifically designed to treatment duck viral hepatitis and preparation method thereof.
Background technology
Duck viral hepatitis is common acute, the height lethal infectious disease of one being caused by DHV, 2 week age of main infection is with interior duckling, take opisthotonus, beak end and pawl point congestion, be mulberry as feature clinically, cut open the visible liver enlargement of inspection and have a large amount of hemorrhagic speckles, mortality rate is very high, is one of principal disease of the foster duck industry of harm.
Family's poultry infectious bursal disease is a kind of common transmittable disease being caused by poultry infectious bursal disease virus, age in main infection 3-6 week poultry, clinically take diarrhoea, arrange white thickness or water sample loose stool as feature, mortality rate is very high, very harmful to poultry.
Newcastle is that the one being caused by Avian pneumo-encephalitis virus is acute, height contagious disease, clinically with the urgency of falling ill, dyspnea, pileum purple is black, diarrhoea, cloaca is hemorrhage, downright bad, and glandular stomach nipple, glandular stomach and muscular stomach intersection and duodenal hemorrhage are feature, mortality rate approaches 100%, very harmful to poultry.
Viral disease spreads all over more or less a hundred country of five continents, is widely distributed.At present, treat such disease the most frequently used be Chinese medicine and antiviral Western medicine, Chinese medicine is because its prescription is unreasonable or just simple pulverizing, particle diameter is excessive, drug release is slower, causes its bioavailability lower, and the approach that Chinese medicine is used is spice or drinking-water, when poultry is ill, search for food all little with amount of drinking water, so clinical effectiveness is not fine; And various antiviral Western medicine are as ribavirin, amantadine etc., the Ministry of Agriculture bans use of.
Therefore researching and developing a kind of specific medicament for the treatment of the viral diseases such as infectious bursal disease, newcastle, duck viral hepatitis is one of this field scientific research technical staff new problem anxious to be resolved.
Summary of the invention
The object of the invention is to overcome above-mentioned weak point, a kind of reasonable recipe is provided, prepares simply, lights sootiness conveniently, smog that sootiness produces is all-pervasive, sterilization control comprehensively thoroughly, bioavailability is high, successful, has no drug resistance and the pure Chinese medicine composition of the viral disease such as effective treatment infectious bursal disease of toxic and side effects, newcastle, duck viral hepatitis and preparation method thereof.
Implementation of the present invention is as follows for achieving the above object: a kind of pure Chinese medicine composition for the treatment of the viral diseases such as infectious bursal disease, newcastle, duck viral hepatitis, by following component by weight mixed preparing form: Radix Isatidis 15-35 part, Fructus Forsythiae 15-25 part, Radix Bupleuri 15-35 part, Folium Artemisiae Argyi 15-30 part, Rhizoma Atractylodis 15-30 part, Folium Isatidis 15-40 part, Radix Glycyrrhizae 10-35 part, Herba Artemisiae Scopariae 15-35 part.
On the basis of such scheme, described various component optimum ratio amounts are: 25 parts of Radix Isatidis, 20 parts of Fructus Forsythiaes, 25 parts of Radix Bupleuri, 20 parts of Folium Artemisiae Argyis, 25 parts of Rhizoma Atractylodis, 25 parts of Folium Isatidiss, 15 parts, Radix Glycyrrhizae, 25 parts of Herba Artemisiae Scopariaes.
Treat a preparation method for the pure Chinese medicine composition of the viral diseases such as infectious bursal disease, newcastle, duck viral hepatitis, carry out as follows:
(1) the various compositions in prescription are pulverized respectively to rear mistake 100 mesh sieves;
(2) take by weight Radix Isatidis 15-35 part, Fructus Forsythiae 15-25 part, Radix Bupleuri 15-35 part, Folium Artemisiae Argyi 15-30 part, mix 5-10 minute to even;
(3) take by weight Rhizoma Atractylodis 15-30 part, Folium Isatidis 15-40 part, Radix Glycyrrhizae 10-35 part, Herba Artemisiae Scopariae 15-35 part, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
The medicinal property of each component is as follows:
Herba Artemisiae Scopariae: be slightly cold, bitter, pungent, return liver, stomach, spleen, gallbladder meridian, there is the function of eliminating damp-heat, promoting the function of the gallbladder to alleviate jaundice; Cure mainly jaundice, oliguria, eczema pruritus.
Radix Bupleuri: pungent, bitter, be slightly cold, return liver, gallbladder, lung meridian, there is the function of delivering with inner, elevate a turnable ladder yang-energy, dispersing the stagnated live-QI to relieve the stagnation of QI; Cure mainly cold, fever, alternate attack of chill and fever, insufficiency of the spleen chronic diarrhea, proctoptosis.
Radix Glycyrrhizae: sweet, flat, return lung, the heart, spleen channel, there is invigorating the spleen and replenishing QI, expelling phlegm for arresting cough and middle emergency, removing toxic substances, coordinating the actions of various ingredients in a prescription, cushion toxicity, strong function; Cure mainly weakness of the spleen and stomach, cough with asthma, poisoning.
Radix Isatidis: bitter, cold, GUIXIN, stomach warp, have the function of removing heat from blood sore-throat relieving, heat-clearing and toxic substances removing; Cure mainly laryngopharynx swelling and pain, aphtha of the mouth and tongue, skin ulcer general edema with yellowish skin poison, maculae caused by violent heat pathogen.
Folium Isatidis: bitter, cold, GUIXIN, stomach warp, have the function of heat-clearing and toxic substances removing, blood cooling and ecchymoses removing; Cure mainly calentura and send out speckle, laryngopharynx swelling and pain, hematodiarrhoea, jaundice, carbuncle, erysipelas etc.
Rhizoma Atractylodis: acrid, bitter, warm, return spleen, stomach, Liver Channel, there is the function of drying damp and strengthening spleen, expelling wind and cold, improving eyesight; Cure mainly have loose bowels, edema, anemofrigid-damp arthralgia, anemofrigid cold, nyctalopia etc.
Folium Artemisiae Argyi: acrid, bitter, warm, return liver,kidney,spleen warp, there is the function of dispersing cold for relieving pain, warming the meridian for stopping bleeding; Cure mainly anemofrigid-damp arthralgia, tripe abdomen cold type of pain etc.
Fructus Forsythiae: bitter, cold, return lung, the heart, small intestine meridian, there is the function of heat-clearing and toxic substances removing, dispersing swelling and dissipating binds; Cure mainly epidemic febrile disease heating, skin ulcer general edema with yellowish skin poison etc.
All taste Chinese medicine, according to Chinese medical theory compatible combination, for pathogenic microorganism, clinical symptoms and the pathological change of the viral diseases such as infectious bursal disease, newcastle, duck viral hepatitis, is brought into play the effect for the treatment of both the principal and secondary aspects of a disease above.
The invention has the beneficial effects as follows: reasonable recipe, preparation is simple, and substep mixes more even; Pure Chinese medicine composition is pollution-free, no drug residue, have no drug resistance, and cost is low, draws materials wide, lights sootiness convenient, smog that sootiness produces is all-pervasive, sterilization control comprehensively thoroughly, bioavailability is high, curative effect highly significant.The present invention is according to Chinese veterinarian's traditional theory, optimize this eight tastes Chinese medicine, and make them according to optimum ratio, form pure Chinese powder medicine, clinical practice proves, the viral diseases such as treatment infectious bursal disease, newcastle, duck viral hepatitis are had to specially good effect, and make its product meat reach nuisanceless requirement, meet the export standard of product, effectively guaranteed that people's is healthy.
The specific embodiment
Below in conjunction with preferred embodiment, to according to the specific embodiment provided by the invention, details are as follows:
Embodiment 1
A kind of pure Chinese medicine composition for the treatment of the viral diseases such as infectious bursal disease, newcastle, duck viral hepatitis and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in prescription are pulverized respectively to rear mistake 100 mesh sieves;
(2) take by weight 150 parts of Radix Isatidis, 150 parts of Fructus Forsythiaes, 150 parts of Radix Bupleuri, 150 parts of Folium Artemisiae Argyis, mix 5-10 minute to even;
(3) take by weight 150 parts of Rhizoma Atractylodis, 150 parts of Folium Isatidiss, 100 parts, Radix Glycyrrhizae, 150 parts of Herba Artemisiae Scopariaes, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Embodiment 2
A kind of pure Chinese medicine composition for the treatment of the viral diseases such as infectious bursal disease, newcastle, duck viral hepatitis and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in prescription are pulverized respectively to rear mistake 100 mesh sieves;
(2) take by weight 250 parts of Radix Isatidis, 200 parts of Fructus Forsythiaes, 250 parts of Radix Bupleuri, 250 parts of Folium Artemisiae Argyis, mix 5-10 minute to even;
(3) take by weight 250 parts of Rhizoma Atractylodis, 250 parts of Folium Isatidiss, 250 parts, Radix Glycyrrhizae, 250 parts of Herba Artemisiae Scopariaes, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Embodiment 3
A kind of pure Chinese medicine composition for the treatment of the viral diseases such as infectious bursal disease, newcastle, duck viral hepatitis and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in prescription are pulverized respectively to rear mistake 100 mesh sieves;
(2) take by weight 350 parts of Radix Isatidis, 250 parts of Fructus Forsythiaes, 350 parts of Radix Bupleuri, 300 parts of Folium Artemisiae Argyis, mix 5-10 minute to even;
(3) take by weight 300 parts of Rhizoma Atractylodis, 400 parts of Folium Isatidiss, 350 parts, Radix Glycyrrhizae, 350 parts of Herba Artemisiae Scopariaes, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Clinical trial:
By every product of the present invention 50 grams of placements together, then light, lose naked light, every day 1-2 time, be used in conjunction 3-5 day, airtight door window, the ventilation of windowing after 45 minutes.This product arrives whole body disease preventing and treating after mainly absorbing by mouth and nose etc.
Table 1 is the field applicable cases contrast of the present invention and other medicines treatment duck viral hepatitis:
| Numbering | Group | Mortality rate % | Cure rate % | During end, there is symptom rate % |
| I | Blank group | 31.3 | 48.2 | 20.5 |
| II | Duck powder for curing hepatitis group | 11.8 | 74.0 | 14.2 |
| III | Chinese medicine composition of the present invention | 7.9 | 83.3 | 8.8 |
This clinical effectiveness statistical analysis, present composition treatment group and duck powder for curing hepatitis group extremely significantly (P < 0.01) of difference compared with aspect cure rate.
Table 2 is field applicable cases contrasts of the present invention and other medicines treatment infectious bursal disease:
| Numbering | Group | Mortality rate % | Cure rate % | During end, there is symptom rate % |
| I | Blank group | 21.2 | 45.3 | 33.5 |
| II | Fuzheng Jiedu powder group | 9.5 | 79.4 | 11.1 |
| III | Chinese medicine composition of the present invention | 6.9 | 85.8 | 7.3 |
This clinical effectiveness statistical analysis, present composition treatment group and Fuzheng Jiedu powder group significant difference (P < 0.05) compared with aspect cure rate.
Table 3 is field applicable cases contrasts of the present invention and other medicines treatment newcastle disease:
| Numbering | Group | Mortality rate % | Cure rate % | During end, there is symptom rate % |
| I | Blank group | 33.9 | 44.6 | 21.5 |
| II | Antipyretic and detoxicated loose group | 10.2 | 75.7 | 14.1 |
| III | Chinese medicine composition of the present invention | 7.9 | 85.1 | 7.0 |
This clinical effectiveness statistical analysis, present composition treatment group and antipyretic and detoxicated loose group of all extremely significantly (P < 0.01) of difference compared with aspect cure rate.
The above-mentioned detailed description that pure Chinese medicine composition to viral diseases such as this treatment infectious bursal disease, newcastle, duck viral hepatitiss and preparation method thereof carries out with reference to embodiment; illustrative rather than determinate; can list several embodiment according to institute's limited range; therefore in the variation and the modification that do not depart under general plotting of the present invention, within should belonging to protection scope of the present invention.
Claims (3)
1. treat a pure Chinese medicine composition for infectious bursal disease, newcastle, duck viral hepatitis, it is characterized in that by following component by weight mixed preparing form: Radix Isatidis 15-35 part, Fructus Forsythiae 15-25 part, Radix Bupleuri 15-35 part, Folium Artemisiae Argyi 15-30 part, Rhizoma Atractylodis 15-30 part, Folium Isatidis 15-40 part, Radix Glycyrrhizae 10-35 part, Herba Artemisiae Scopariae 15-35 part.
2. the pure Chinese medicine composition for the treatment of infectious bursal disease according to claim 1, newcastle, duck viral hepatitis, it is characterized in that by following component by weight mixed preparing form: 25 parts of Radix Isatidis, 20 parts of Fructus Forsythiaes, 25 parts of Radix Bupleuri, 20 parts of Folium Artemisiae Argyis, 25 parts of Rhizoma Atractylodis, 25 parts of Folium Isatidiss, 15 parts, Radix Glycyrrhizae, 25 parts of Herba Artemisiae Scopariaes.
3. a preparation method for the pure Chinese medicine composition for the treatment of infectious bursal disease according to claim 1, newcastle, duck viral hepatitis, is characterized in that carrying out as follows:
(1) the various compositions in prescription are pulverized respectively to rear mistake 100 mesh sieves;
(2) take by weight Radix Isatidis 15-35 part, Fructus Forsythiae 15-25 part, Radix Bupleuri 15-35 part, Folium Artemisiae Argyi 15-30 part, mix 5-10 minute to even;
(3) take by weight Rhizoma Atractylodis 15-30 part, Folium Isatidis 15-40 part, Radix Glycyrrhizae 10-35 part, Herba Artemisiae Scopariae 15-35 part, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
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| CN201210041646.5A CN102579593B (en) | 2012-02-23 | 2012-02-23 | Pure Chinese medicinal composition for treating infectious bursal disease, newcastle disease, duck virus hepatitis and other viral diseases, as well as preparation method thereof |
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| CN104645116A (en) * | 2015-03-11 | 2015-05-27 | 格特生物制药（天津）有限公司 | Traditional Chinese medicine oral liquid for treating duck viral hepatitis and preparation method of traditional Chinese medicine oral liquid |
| CN108308378A (en) * | 2018-01-23 | 2018-07-24 | 合肥仙之峰农业科技有限公司 | A kind of feed and preparation method of prevention chicken seasonal febrile diseases |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2005067948A2 (en) * | 2004-01-13 | 2005-07-28 | Jinhua Wang | Biological medicine for treating various diseases caused by various virus, bacterial infection |
| CN101554414A (en) * | 2008-04-09 | 2009-10-14 | 北京大北农动物保健科技有限责任公司 | Traditional Chinese medicine mixture for treating livestock and poultry virosis and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2005067948A2 (en) * | 2004-01-13 | 2005-07-28 | Jinhua Wang | Biological medicine for treating various diseases caused by various virus, bacterial infection |
| CN101554414A (en) * | 2008-04-09 | 2009-10-14 | 北京大北农动物保健科技有限责任公司 | Traditional Chinese medicine mixture for treating livestock and poultry virosis and preparation method thereof |
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