CN102640876A - Feed and injection used for treating duck virus hepatitis and preparation method of feed and injection - Google Patents

Abstract

The invention provides a feed, comprising a Chinese herbal medicine composition used for treating duck virus hepatitis and a feed carrier, wherein the Chinese herbal medicine composition further comprises oriental wormwood, uncaria, indian epimeredi herb, schizonepeta, gastrodia elata, safflower, citron, llicis routundae cortex, sculellaria barbata, common reed rhizome, pipewort, fructus forsythiae, folium apocyni veneti, radix angelicae pubescentis, codonopsis pilosula and Chinese yam. The feed containing the Chinese herbal medicine composition can overcome various defects of traditional Chinese medicine and Western medicine in the prior art, has obvious treatment effect on ducks suffering from the duck virus hepatitis, treats both principal and secondary aspects of the duck virus hepatitis, strengthens the body resistance to eliminate pathogenic factors and has the advantages of high cure rate, no toxic or side effect, low recurrence rate, no phytotoxicity and low cost.

Description

Be used to treat feed, parenteral solution and the preparation method of duck virus hepatitis

Technical field

The present invention relates to the herbal medicine technical field, relate in particular to a kind of Chinese medicine composition that is used to treat duck virus hepatitis.

Background technology

(duck viral hepatitis is by DHV (duck hepatitis virus, one of eqpidemic disease that the harm duckling that DHV) causes is the most serious DVH) to duck virus hepatitis.This disease is propagated soon, morbidity is anxious, the death rate is high; Cuing open the inspection liver has obvious blutpunkte and blood spots, and the duckling age in days is more little, and the death rate is high more; High mortality can reach 90%～95%; This disease is except that directly causing infected duck death, and the duck immunocompetence that stock is got off receives heavy damage, thereby causes immuning failure.

Since 1945 found duck virus hepatitis by Levine and Hofstad, existing twenties country's these diseases of report were called as the pandemic infection disease.In China, Zi Huangjun the people such as builds and reports that Shanghai takes place after this disease, and more than 10 province (city) and area this disease of report are successively arranged, and its cause of disease is I type DHV.

The characteristic of duck virus hepatitis is a sudden onset, propagates soon, and the course of disease is short, and the death rate is high, sudden onset, down in spirits; The drop-head hogback subtracts food and does not eat, and nonvoluntary activity is closed one's eyes and dozed off, and contacts to earth with head, diarrhoea occurs; Sick subsequently duck is uneasy, nervous symptoms occurs, and ataxia is turn-taked, and head is to palintrope, and bipod is twitched backward; Whole body spasm, dead front backward, bipod is struggled and is stretched backward, is that arch is counter to be opened, because of expiratory dyspnea very fast dead; Clinical anatomic is characterized as: the visible liver enlargement of major lesions, and quality is soft, embrittlement, outward appearance pinkiness or khaki sex change, there are needle point appearance size darkviolet blutpunkte or sheet blood cake, gall-bladder enlargement in the surface; Be full of bile, splenaemia, enlargement, outward appearance also has piebald, and heart is as boiling shape, and other organ does not have obvious pathology.

The present prevention of duck virus hepatitis disease is main with vaccine inoculation mainly, and immune effect is also relatively good, if but indivedual regional immune density not high also can cause should disease popular.Behind the duck infection morbidity, also there is not the specific treatment medicine.Though antibiotic that uses during duck produces at present and chemical synthetic drug treatment duck virus hepatitis have good effect, price is more expensive, and the source of goods is in short supply; And as long as a large amount of administration antibiotic or chemical synthetic drug, all have residually in the duck, export inspection is all return; And in recent years, the Ministry of Agriculture prohibites duck is used antibiotic, so; For raising the base, how to select drug residue free, and prevent that effective medicine from being the task of top priority.

Chinese medicine has no side effect, does not have the resistance to the action of a drug, its role is to the qi and blood of conditioning body; Soothing the liver reason spleen; The metabolic function and the immunologic function of adjustment body have antivirus action again, so body recovery is fast; More not recurring after, is the problem of the concentrated research of many in recent years veterinary work persons with herbal control duckling virus hepatitis.

The Chinese medicine of being developed at present is good not as Western medicine to the treatment curative effect of duck virus hepatitis, therefore has report that Western medicine and Chinese traditional medicine composition are used, though it has the advantage of relative low price; But produce effects speed is slower, just can make transference cure when medicine time is longer, does not particularly have bladder because of aquatic bird; Glomerulus is simple in structure, and effective filtration pressure is lower, and it is little to filter area; Medicine to discharging through kidney is very sensitive, causes easily and is poisoned to death, nor can thoroughly eliminate the medicament residue problem of duck.

Summary of the invention

Technical problem to be solved by this invention is the feed that is to provide a kind of novel comprising to be used to treat the Chinese medicine composition of duck virus hepatitis, adopts the feed that contains this Chinese medicine composition can overcome the various defectives of Chinese medicine of the prior art and Western medicine, has evident in efficacy to the treatment of the duck that suffers from duck virus hepatitis; Treat both principal and secondary aspect of disease, strengthening vital QI to eliminate pathogenic factors, cure rate is high; Have no side effect; Be difficult for recurrence, no poisoning, low cost and other advantages.

In order to solve the problems of the technologies described above; The invention provides a kind of feed that is used for; It comprises Chinese medicine composition and the feed vector that is used to treat duck virus hepatitis, and said Chinese medicine composition further comprises oriental wormwood, yncaria stem with hooks, windproof, schizonepeta, rhizoma Gastrodiae, safflower, citron, iron holly bark, Sculellaria barbata, reed rhizome, pipewort, the capsule of weeping forsythia, Folium Apocyni Veneti, levisticum, Radix Codonopsis and Chinese yam.

Wherein, The said Chinese medicine composition that is used for treating the animal duck virus hepatitis, the ratio of weight and number of various components can for: oriental wormwood 10～16 weight portions, yncaria stem with hooks 40～50 weight portions, windproof 18～23 weight portions, schizonepeta 15～20 weight portions, rhizoma Gastrodiae 35～45 weight portions, safflower 8～14 weight portions, citron 20～25 weight portions, iron holly bark 17～21 weight portions, Sculellaria barbata 12～16 weight portions, reed rhizome 10～13 weight portions, pipewort 20～25 weight portions, the capsule of weeping forsythia 27～32 weight portions, spread out sackcloth 25～30 weight portions, levisticum 8～12 weight portions, Radix Codonopsis 13～17 weight portions, Chinese yam 11～15 weight portions.

Wherein, The said Chinese medicine composition that is used for treating the animal duck virus hepatitis, the ratio of weight and number of various components can for: oriental wormwood 13～16 weight portions, yncaria stem with hooks 45～50 weight portions, windproof 20～23 weight portions, schizonepeta 17～20 weight portions, rhizoma Gastrodiae 40～45 weight portions, safflower 11～14 weight portions, citron 22～25 weight portions, iron holly bark 19～21 weight portions, Sculellaria barbata 14～16 weight portions, reed rhizome 12～13 weight portions, pipewort 22～25 weight portions, the capsule of weeping forsythia 30～32 weight portions, spread out sackcloth 27～30 weight portions, levisticum 10～12 weight portions, Radix Codonopsis 15～17 weight portions, Chinese yam 13～15 weight portions.

Wherein, the said Chinese medicine composition that is used for treating duck virus hepatitis can also comprise the hawthorn and the membrane of a chicken's gizzard, and the said hawthorn and the membrane of a chicken's gizzard ratio of weight and number in said Chinese medicine composition is hawthorn 3～5 weight portions, the membrane of a chicken's gizzard 1～3 weight portion.

Wherein, the ratio of weight and number of said feed vector and said Chinese medicine composition additive can be 100 weight portions: 1～5 weight portion.

Wherein, Said feed can further include feed adhesive; The ratio of weight and number of said feed vector and said feed adhesive can be 100 weight portions: 10～20 weight portions, comprise Strong flour, starch, ammonium sulfate, sodium carbonate and sodium acid carbonate in the said feed adhesive, and the ratio of weight and number of each composition does in the said feed adhesive; Strong flour is 20 ~ 30 parts, and starch is 30 ~ 50 parts; The gross weight umber ratio of ammonium sulfate, sodium carbonate and sodium acid carbonate is 3 ~ 8 parts; Said starch is preferably cornstarch, and wherein with respect to 100 parts of starch gross weights, farinose ratio of weight and number is 70 ~ 90 parts, and the ratio of weight and number of ripe starch is 10 ~ 20 parts; Said Strong flour is the protein wt degree greater than 13.5% flour.

For solving the problems of the technologies described above, the present invention also provides the preparation method of above-mentioned feed, and it comprises:

The first step; Said oriental wormwood, yncaria stem with hooks, windproof, schizonepeta, rhizoma Gastrodiae, safflower, citron, iron holly bark, Sculellaria barbata, reed rhizome, pipewort, the capsule of weeping forsythia, Folium Apocyni Veneti, levisticum, Radix Codonopsis and Chinese yam are ground to form 100～200 order fine powders by said mixed, be prepared into said Chinese medicine additive;

Second the step, feed adhesive is added in proportion, with respect to the feed adhesive of 100 weight portions, in the water of 15～30 weight portions the beginning modified, refining temperature is 62 ~ 68 ℃, pours in the spraying machine after stirring;

In the 3rd step, said feed vector is pulverized, and grinding particle size is 300～550mm, makes its fine powder amount reach more than 92% of total material;

In the 4th step, the feed vector after said the 3rd step pulverized is poured in the spraying machine, mixes with feed adhesive after modified, and water temperature is modulated at 60～70 ℃ in the spraying machine, opens sprayer, stirs 1 minute～3 minutes, and it is expanded to continue to be warming up to 90 ℃ of completion;

The 5th step, pulverize expanded product, add the Chinese medicine additive that the first step obtains again, after the mixing, add water with respect to 1 ~ 10 part of the parts by weight of the mixture of 100 weight portions, to put into granulator and granulate, the granulator electric current is 175A～195A;

In the 6th step, the back of granulating is dry, and baking temperature is 105 ℃～115 ℃, drying time 15～25min; Cooling then, the cooling blower electric current is 31A, packing.

For solving the problems of the technologies described above, the present invention also provides a kind of parenteral solution, and it comprises oriental wormwood, yncaria stem with hooks, windproof, schizonepeta, rhizoma Gastrodiae, safflower, citron, iron holly bark, Sculellaria barbata, reed rhizome, pipewort, the capsule of weeping forsythia, Folium Apocyni Veneti, levisticum, Radix Codonopsis and Chinese yam.

Wherein, The weight fraction of each component ratio does in the said parenteral solution, oriental wormwood 10～16 weight portions, yncaria stem with hooks 40～50 weight portions, windproof 18～23 weight portions, schizonepeta 15～20 weight portions, rhizoma Gastrodiae 35～45 weight portions, safflower 8～14 weight portions, citron 20～25 weight portions, iron holly bark 17～21 weight portions, Sculellaria barbata 12～16 weight portions, reed rhizome 10～13 weight portions, pipewort 20～25 weight portions, the capsule of weeping forsythia 27～32 weight portions, spreads out sackcloth 25～30 weight portions, levisticum 8～12 weight portions, Radix Codonopsis 13～17 weight portions, Chinese yam 11～15 weight portions.

For solving the problems of the technologies described above, the present invention also provides the preparation method of above-mentioned parenteral solution, and it comprises:

The first step is mixed pulverizing, boiling 2～4 times in proportion with oriental wormwood, yncaria stem with hooks, windproof, schizonepeta, rhizoma Gastrodiae, safflower, citron, iron holly bark, Sculellaria barbata, reed rhizome, pipewort, the capsule of weeping forsythia, Folium Apocyni Veneti, levisticum, Radix Codonopsis and Chinese yam; Each decocting time is 2 hours～3 hours, and the quality of adding is 2～4 times of first step mixture quality, merges decoction liquor; Filter, filtrating is concentrated into syrupy shape, adding determining alcohol is the ethanol more than 95%; The ethanol content that adds is 1～2 times of mixture quality of the first step; After leaving standstill 12 hours～24 hours, centrifugal filtration, filtrating is adjusted to filtrating pH7～8 with 40%～50% NaOH;

In second step, the filtrating with the first step obtains adds 0.5%～1% active carbon and boiled 18～22 minutes, filters; Decarburization adds the injection water, and the crude drug concentration that makes parenteral solution is 2g/ml～4g/ml; Can was sterilized in the 500ml saline bottle 1.5 hours～2 hours, after freezing a couple of days, filtered.

Beneficial effect of the present invention:

With respect to the medicine that is used to treat duck virus hepatitis of the prior art, adopt the feed contain this Chinese medicine composition can overcome the various defectives of Chinese medicine of the prior art and Western medicine, have evident in efficacy to the treatment of the duck that suffers from duck virus hepatitis; Treat both principal and secondary aspect of disease, strengthening vital QI to eliminate pathogenic factors, cure rate is high; Have no side effect; Be difficult for recurrence, no poisoning, low cost and other advantages.

The specific embodiment

Chinese veterinarian's theory thinks that duck virus hepatitis is because excessive heat of liver and gallbladder and the diarrhea due to damp-heat that diseases caused by external factors virus causes.The thermoae wind of then giving birth to, liver wind agitation just shows as symptoms such as stupor, spasm, tic and diarrhoea clinically, should be clearing heat and detoxicating in treatment, soothing liver-qi stagnation, relieving convulsion and spasm, the livering that relaxes stagnates, and strengthens the duck Abwehrkraft des Koepers.

According to above-mentioned theory and principle; The invention provides a kind of like this Chinese medicine composition that is used to treat duck virus hepatitis, it comprises: oriental wormwood, yncaria stem with hooks, windproof, schizonepeta, rhizoma Gastrodiae, safflower, citron, iron holly bark, Sculellaria barbata, reed rhizome, pipewort, the capsule of weeping forsythia, Folium Apocyni Veneti, levisticum, Radix Codonopsis and Chinese yam.

Oriental wormwood: bitter, suffering, cold nature is gone into spleen, stomach, liver, gallbladder channel; Have clearing away damp-heat, the effect of removing jaundice subcutaneous ulcer is used for jaundice; No matter damp and hot yang jaundice or cold-dampness yin jaundice all can be used, and also can be applicable to card such as scanty drak urine due to heat temperature or the damp-warm syndrome, and oriental wormwood includes chlorogenic acid, caffeic acid etc.; Antibiotic, antiviral effect is arranged, can alleviate swelling of liver cell to some extent, fat degenerates or is downright bad.

Yncaria stem with hooks: it is sweet to distinguish the flavor of, and slightly warm in nature is gone into Liver Channel, and the effect of heat-clearing, calming the liver, relieving convulsion and spasm is arranged, and is mainly used in the anxious spasm of giving birth to due to wind or the liver wind agitation of heat, twitch, and restlessness, liver-yang hyperactivity or Liver Channel have the headache of heat dizzy, symptoms such as red eye, swell pain.

Windproof: flavor is hot, sweet, and slightly warm in nature is gone into lung, liver, spleen, urinary bladder channel, and expelling cold and relieving exterior syndrome is arranged, and removing dampness to relieve pain is expellingged wind and relieving convulsion, and antipruritic effect being mainly used in catch cold card and cold-evil's closing, in the syndrome of superficies cold and interior heat etc. of hot pent-up.

Schizonepeta: flavor is hot, and slightly warm in nature is gone into lung, Liver Channel, and inducing sweat and dispelling exogenous evils is arranged, and declares the effect of malicious promoting eruption and blood hemostasis, is mainly used in the fever and headache due to the wind-heat of catching cold, and no matter has sweat lossless, all can use; The headache of attacking on the wind-heat is dizzy, and rash goes out not pass through; The postpartum anemic fainting apoplexy, cards such as discharging fresh blood stool.

Schizonepeta and windproof all belongs to relieving the exterior syndrome with drugs pungent in flavor and warm in property, the article of expelling wind and clearing away cold, and windproof is profit agent in the wind medicine, can dredge wind prevailing over dampness, rise sun and inspire temper, but the power of sweating is not as good as schizonepeta; Schizonepeta property is also gentle, and makings lightly floats, and gets final product dispersing wind and cold, the wind-heat of can loosing again, and what usefulness of two medicines, the power of inducing sweat strengthens, and is the obstruction-removing prescription of catching cold in 4 o'clock.

Rhizoma Gastrodiae: sweet, the property of distinguishing the flavor of is flat, goes into Liver Channel, have calming the liver to stop the wind, spasmolysis, the effect of removing obstruction in channels to relieve pain is mainly used in the dizzy headache of liver-fire flaming, symptoms such as the strong wind tic due to liver-yang hyperactivity, the liver wind agitation, epilepsy.

Rhizoma Gastrodiae and yncaria stem with hooks share, and complement each other, and are usually used in liver wind agitation, symptoms such as the headache due to disturbing on the wind phlegm, dizzy order are deceived, numb limb.

Safflower: warm in nature, flavor is hot, goes into, the heart, Liver Channel, has activating blood to promote menstruation, and the effect of stasis-dispelling and pain-killing is used for amenorrhoea, dysmenorrhoea, and lochia is not all right, the abdominal mass lump in the abdomen, injury from falling down, sore swell and ache and wait disease, " Bencao Jingshu ": red blue colored, be the key medicine of promoting circulation of blood.The bruise mouth person of keeping silent behind its main product, the edge extravesated blood not down, the contrary last centre of punch so coma and dizzy and mouthful keep silent is gone into the heart and gone into liver, makes extravesated blood descending, then dizzy and mouth are kept silent from only.Angina in the abdomen, because extravesated blood not to the utmost, fails before being carrying out, non-activating blood circulation is not then not down; Stasis of blood row then blood is lived, so can end angina, following stillborn foetus also.The medicine of this promoting circulation of blood of red blue flower also, the bruise row of separating, be detained promptly ends, and crosses with making blood capable more than and get killed, safflower has slight excited heart, reduces coronary resistance, the effect of increase coronary flow and myocardial nutritional flow amount.

Citron: flavor is hot, bitter, sour, warm in nature, goes into liver, lung, the spleen channel, has the effect of full vexed, the distending pain in hypochondrium of chest abdomen, coughing with a lot of sputum; Cure mainly the liver depression distending pain in the chest and hypochondrium, this article are hot can manage it and loose, and the catharsis of hardship ability is gone into Liver Channel and can be unclogged and readjusted irritability and pain relieving; Also be used to treat stagnation of the circulation of vital energy abdominal distention, this article gas perfume (or spice) is amusing, and hot row hardship is let out; Go into taste with promoting the circulation of qi wide in, also be used to treat the phlegmatic cough, the chest diaphragm is unfavorable.Bitter dry the falling of these article let out with preventing phlegm from forming and stopping coughing, and hot row is gone into lung and the wide chest of regulating the flow of vital energy, and " herbal classic is met former ": the mandarin orange rafter is two kinds of Buddha's hand, citrons, and nature and flavor are class mutually, is regardless of so " detailed outline " mixes opinion.Cover mandarin orange person Buddha's hand also, rafter person citron is also held concurrently and breaks phlegm water, controls cough gas modern times and stops up, and also gets old person.Remove flesh nuclear and use it, the trouble of multitudinous anacidity receipts.

Iron holly bark: cold in nature, bitter is gone into lung, liver, large intestine channel, has the effect of clearing heat and detoxicating, dampness removing, pain relieving, cures mainly that cold, fever, abscess of throat, stomachache, administration are wetly had loose bowels, jaundice, dysentery, traumatic injury, arthralgia due to wind-dampness, eczema, sore furuncle.

Sculellaria barbata: flavor is hot, bitter, cold in nature, goes into lung channel, Liver Channel, kidney channel, has the effect of clearing heat and detoxicating, diffusing stasis of blood hemostasis, inducing diuresis to reduce edema, and cure mainly: hot malicious carbuncle is swollen; Have sore throat; Lung carbuncle; Acute appendicitis; Scrofula; Venomous snake bite; Traumatic injury; Spit blood; Bleeding from five sense organs or subcutaneous tissue; Blood drenches; Oedema; Ascites and cancer.

Reed rhizome: it is sweet, cold in nature to distinguish the flavor of, and goes into lung channel, stomach warp, is used for clearing heat and promoting fluid, relieving restlessness, and preventing or arresting vomiting, diuresis cures mainly pyreticosis polydipsia, gastropyretic vomiting, cough with lung heat, lung carbuncle pyemesis, the puckery pain of heat pouring, and " Bencao Jingshu ": reed rhizome, it is sweet cold and nontoxic to distinguish the flavor of.The person of quenching one's thirst, middle Jiao has heat, then taste are dry, body fluid being unable to be produced and so also, the beneficial stomach of sweet ability with in, the cold heat drop fire that can remove, the pyrolysis stomach and, free flow of body fluid and ending yearningly then.The hot person of visitor, heat symptoms caused by an exopathgen also, the sweet cold heat symptoms caused by an exopathgen of removing, then objective heat is explained by oneself.The lung being the upper source of fluids, spleen-QI transporting the essence to the whole body, on belong to lung, the beginning can regulating fluid apssage; Following defeated bladder, the kidney being a water ZANG-organ and main two just, there is heat in three families, then frequent urination; Even can not bear less, bad temper is former rapidly also, the pyrolysis of lung, kidney, spleen three families; Multiple its normal road of urine then, fire rises stomach energy, and then gastric disorder causing nausea is vomitted and is not contraryly eaten down and choke and vomit incessantly; Disease during typhoid fever, heat are very then unhappy; Following many yin depletions are so how thirsty rush down sharp people; Pregnant woman's blood deficiency is heart heat then, and sweet cold heat extraction peace stomach also can the therapeutic method to keep the adverse qi flowing downward, thus know lead also.

Pipewort: flavor is hot, sweet, and property is flat, goes into liver, stomach warp, has the effect of wind-dispelling heat-dissipating, removing nebula, is used for the many tears of red eye, swell pain, photophobia due to the wind-heat, cards such as headache due to pathogenic wind-heat, toothache, nasosinusitis.

The capsule of weeping forsythia: bitter, cold nature, go into the heart, liver, courage, small intestinl channel, effect clearing heat and detoxicating, dispersing swelling and dissipating binds is arranged, be mainly used in affection of exogenous wind-heat, warm heat disease heat poison and contain, or warm disease is from the beginning of heat evil still at the part of the body cavity above the diaphragm housing the heart and lungs and when not descending, hot malicious diarrhea, stool is blood down, and heat temperature is demonstrate,proved; Unconsciousness due to high fever agitation to the invasion of pericardium by evil is particularly suitable.

Folium Apocyni Veneti: it is sweet, bitter, cool in nature to distinguish the flavor of, and goes into Liver Channel, has flat liver and calms the nerves, and the effect of clearing away heat and promoting diuresis is used for dizziness due to hyperactivity of liver-YANG, palpitation and insomnia, edema oliguria; High blood pressure, neurasthenia, cards such as ephritis edema.

Levisticum: flavor is hot, bitter, and slightly warm in nature is gone into liver, kidney, urinary bladder channel, has expelling wind and eliminating dampness, and the effect of eliminating cold to stop pain is used for wind-cold-dampness arthralgia; Lumbocrural pain; Few cloudy volt wind headache, cards such as headache dentalgia, " Bencao Jingshu ": levisticum, its main air metal-inflicted wound pain relieving person that hits that trembles with fear; Metal-inflicted wound is that the institute of chill attacks, and then vim and vigour are stopped up and not all right, so it is bitterly more, and the bitter Gan Xinwen of levisticum; Can ward off chill, evil flesh table peace and, the qi and blood circulation of loosing then is so its pain is from only also.The globefish person that runs quickly, kidney is long-pending, and kidney channel is the chill visitor that takes advantage of a weak point in opponent's defence, the globefish that then becomes to run quickly, this medicine is originally gone into the few the moon of foot, so control to globefish.Election of pathogenic wind with epilepsy are also formed by the wind to the epileptic Electoral healing carry on.Woman's hernia lump in the abdomen person, cold-dampness is taken advantage of a weak point in opponent's defence due to the middle kidney man also, bitter can eliminating dampness, temperature can be warded off cold, suffering can be dispersed, cold-dampness is gone and the kidney peace, so main woman's hernia lump in the abdomen and is treated all harmful wind, hundred and saved gouts and do not have for a long time newly also.

Radix Codonopsis: it is sweet to distinguish the flavor of, and property is flat, goes into lung, the spleen channel, and tonifying Qi benefit spleen is arranged; The effect of nourishing blood to promote the production of body fluid is mainly used in spleen-lung Qi deficiency or qi-blood deficiency lassitude hypodynamia, breathes hard, symptoms such as cough spontaneous perspiration, and Radix Codonopsis is longer than the tonifying spleen nourishing the stomach; Transfer regulating the function of middle-JIAO, have the effect of nourishing blood concurrently, its property is flat, invigorating the spleen fortune and not dry; Flavour is cloudy and not wet, can improve modulation on immune status, improves resistance against diseases, promotes to digest and assimilate, and improves metabolism, promotes the absorption of enteron aisle to nutriment.

Chinese yam: sweet, the property of distinguishing the flavor of is flat, goes into lung, spleen, stomach warp, and the tonifying spleen nourishing the stomach is arranged, and beneficial lung reinforces the kidney, and the effect of nourishing Yin and promoting production of body fluid is mainly used in weakness of the spleen and the stomachly, and it is poor that the food of the dysfunction of the spleen in transport is received less, symptoms such as the vexed diarrhoea of gastral cavity.

In the Chinese medicine composition prescription of the present invention, rhizoma Gastrodiae, yncaria stem with hooks and Folium Apocyni Veneti are calming the liver to stop the wind, are the key medicine of treatment duck virus hepatitis, windproof, schizonepeta relieving the exterior syndrome with drugs pungent in flavor and warm in property; Expelling wind and clearing away cold, clearing heat and detoxicating, the dispersing swelling and dissipating binds of Sculellaria barbata, reed rhizome, iron holly bark, pipewort and the capsule of weeping forsythia plays antiviral effect, oriental wormwood, levisticum clearing away damp-heat; Antibiotic, antiviral, alleviate hepatocellular swelling, the citron dispersing stagnated hepatoqi; The safflower activating blood to promote menstruation, stasis-dispelling and pain-killing, Radix Codonopsis and Chinese yam air making-up and spleen enlivening; The enhancing body resistance, all medicines are collaborative, the treatment duck virus hepatitis.

Further preferred, the said Chinese medicine composition that is used to treat duck virus hepatitis only is made up of said components.

The said Chinese medicine composition that is used for treating duck virus hepatitis, the ratio of weight and number of various components can be preferably: oriental wormwood 10～16 weight portions, yncaria stem with hooks 40～50 weight portions, windproof 18～23 weight portions, schizonepeta 15～20 weight portions, rhizoma Gastrodiae 35～45 weight portions, safflower 8～14 weight portions, citron 20～25 weight portions, iron holly bark 17～21 weight portions, Sculellaria barbata 12～16 weight portions, reed rhizome 10～13 weight portions, pipewort 20～25 weight portions, the capsule of weeping forsythia 27～32 weight portions, spread out sackcloth 25～30 weight portions, levisticum 8～12 weight portions, Radix Codonopsis 13～17 weight portions, Chinese yam 11～15 weight portions.

The said Chinese medicine composition that is used for treating the animal duck virus hepatitis, the ratio of weight and number of various components also can further be preferably: oriental wormwood 13～16 weight portions, yncaria stem with hooks 45～50 weight portions, windproof 20～23 weight portions, schizonepeta 17～20 weight portions, rhizoma Gastrodiae 40～45 weight portions, safflower 11～14 weight portions, citron 22～25 weight portions, iron holly bark 19～21 weight portions, Sculellaria barbata 14～16 weight portions, reed rhizome 12～13 weight portions, pipewort 22～25 weight portions, the capsule of weeping forsythia 30～32 weight portions, spread out sackcloth 27～30 weight portions, levisticum 10～12 weight portions, Radix Codonopsis 15～17 weight portions, Chinese yam 13～15 weight portions.

The said Chinese medicine composition that is used for treating duck virus hepatitis can also comprise hawthorn, the membrane of a chicken's gizzard.

Hawthorn: flavor acid, sweet, slightly warm in nature is gone into spleen, stomach, Liver Channel, is used for food digesting stomach fortifying, and the promoting the circulation of qi stasis of blood of loosing mainly is used for treating accumulation of food in the stomach and intes tine due to indigestion, has loose bowels, dysentery, hawthorn is the staple of treatment indigestion, hawthorn can increase the secretion of peptic digest enzyme, promotes to digest; Shigella dysenteriae, Escherichia coli, Pseudomonas aeruginosa, staphylococcus aureus etc. had the obvious suppression effect.

The membrane of a chicken's gizzard: it is sweet to distinguish the flavor of, cold, goes into spleen, stomach, small intestine, urinary bladder channel, has food digesting stomach fortifying, the effect of arresting seminal emission; Be used for the dyspepsia turgor, dysentery is rushed down in vomiting gastric disorder causing nausea, and infantile malnutrition due to digestive disturbances or intestinalparasites is quenched one's thirst; Lose to drown, larynx numbness acute tonsillitis, cards such as noma aphtha, " Bencao Jingshu ": gizzard is the spleen of chicken, is the institute of digesting and absorbing the essence of foodstuff of disappearing.Its gas lead to large intestine, bladder two warps.Have heat then to let out the dysentery something lost and drown, the gas that must be slightly cold then heat removes, and loses the self-healing of drowning and let out dysentery.Be tired of because of heat and give birth to that heat is gone so be tired of certainly only also.Control all infantile malnutrition due to digestive disturbances or intestinalparasites sore multiple-effect with it this life again.

Through adding the hawthorn and the membrane of a chicken's gizzard, can eliminate eating accumulation, promote digestion, increase enterogastric peristalsis, in case abdominal fullness and distention; Food is few, and dysentery has and regulates the flow of vital energy, and stomach, the effect of invigorating the spleen; Duck appetite is heightened, improve resistance against diseases and immunologic function, reduce disease incidence rate, play a role in health care.

Said hawthorn, the ratio of weight and number of the membrane of a chicken's gizzard in said Chinese medicine composition are hawthorn 3～5 weight portions, the membrane of a chicken's gizzard 1～3 weight portion.

Said Chinese traditional medicine composition pharmaceutical dosage form can be decoction, powder, parenteral solution, honey refining pill, hydration pill, tablet, capsule, oral liquid, granule, jelly or syrup.

The present invention also provides the preparation method of the parenteral solution of the above-mentioned Chinese medicine composition that is used to treat duck virus hepatitis, and it comprises:

The first step is mixed pulverizing with each component, boiling 2～4 times, and each decocting time is 2 hours～3 hours; The quality that adds is 2～4 times of first step mixture quality, merges decoction liquor, filters; Filtrating is concentrated into syrupy shape, and adding determining alcohol is the ethanol more than 95%, and the ethanol content of adding is 1～2 times of mixture quality of the first step; After leaving standstill 12 hours～24 hours, centrifugal filtration, filtrating is adjusted to filtrating pH7～8 with 40%～50% NaOH;

In second step, the filtrating with the first step obtains adds 0.5%～1% active carbon and boiled 18～22 minutes, filters; Decarburization adds the injection water, and the crude drug concentration that makes parenteral solution is 2g/ml～4g/ml; Can was sterilized in the 500ml saline bottle 1.5 hours～2 hours, after freezing a couple of days, filtered.

The present invention also provides the preparation method of the oral liquid of the above-mentioned Chinese medicine composition that is used to treat duck virus hepatitis, and it comprises:

1, said component is mixed in proportion, be ground into powder;

2, the 1st step was obtained powder and add in the cold water and soaked 24 hours～36 hours, with slow fire boiling, decocting time is 1 hour～2 hours, and decoction liquor is filtered, and obtains first filtrating, and the quality of the water that is added is 3～5 times of the powder quality that obtained in the 1st step;

3, the filter residue that the 2nd step filter was obtained adds in the cold water once more, with slow fire boiling 1 hour～2 hours, filters and obtains second filtrating, identical in the quality of the water that is added and the 2nd step;

4, merge twice filtrating, decompression concentrates and removes part water, obtains said oral liquid, and the crude drug concentration of said oral liquid is preferably 2 g/ml～4g/ml.

The administering mode of said Chinese medicine composition is oral or injection.

The present invention also provides a kind of feed, comprises above-mentioned Chinese medicine composition additive, feed vector and feed adhesive in this feed.

Said feed vector is preferably one or more in corn, wheat, barley, the dregs of beans.

The ratio of weight and number of said feed vector and said Chinese medicine composition additive can be 100 weight portions: 1～5 weight portion; Further be preferably 100 weight portions: 2～4 weight portions, the ratio of weight and number of said feed vector and said feed adhesive can be 100 weight portions: 10～20 weight portions.

Can also comprise other additives such as chlorogenic acid, Tea Polyphenols, ethoxyquin plus, apple polyphenol, vitamin, amino acid, flavor enhancement in the said feed.

Said flavor enhancement further comprises: vomiting nut, betel nut and big scallion oil.

Comprise other components such as Strong flour, starch, ammonium sulfate, sodium carbonate and sodium acid carbonate in the said feed adhesive.

The ratio of weight and number of each composition does in the said feed adhesive, and Strong flour is 20 ~ 30 parts, and starch is 30 ~ 50 parts; The gross weight umber ratio of ammonium sulfate, sodium carbonate and sodium acid carbonate is 3 ~ 8 parts; Said starch is preferably cornstarch, and wherein with respect to 100 parts of starch gross weights, farinose ratio of weight and number is 70 ~ 90 parts, and the ratio of weight and number of ripe starch is 10 ~ 20 parts; Said Strong flour is the protein wt degree greater than 13.5% flour.

The present invention also provides the preparation method of above-mentioned fodder compound, and it comprises:

The first step; Said oriental wormwood, yncaria stem with hooks, windproof, schizonepeta, rhizoma Gastrodiae, safflower, citron, iron holly bark, Sculellaria barbata, reed rhizome, pipewort, the capsule of weeping forsythia, Folium Apocyni Veneti, levisticum, Radix Codonopsis and Chinese yam are ground to form 100～200 order fine powders by said mixed, be prepared into said Chinese medicine additive;

Second the step, feed adhesive is added in proportion, with respect to the feed adhesive of 100 weight portions, in the water of 15～30 weight portions the beginning modified, refining temperature is 62 ~ 68 ℃, pours in the spraying machine after stirring;

In the 3rd step, said feed vector is pulverized, and grinding particle size is 300～550mm, makes its fine powder amount reach more than 92% of total material;

In the 4th step, the feed vector after said the 3rd step pulverized is poured in the spraying machine, mixes with feed adhesive after modified, and water temperature is modulated at 60～70 ℃ in the spraying machine, opens sprayer, stirs 1 minute～3 minutes, and it is expanded to continue to be warming up to 90 ℃ of completion;

The 5th step, pulverize expanded product, add the Chinese medicine additive that the first step obtains again, after the mixing, add water with respect to 1 ~ 10 part of the parts by weight of the mixture of 100 weight portions, to put into granulator and granulate, the granulator electric current is 175A～195A;

In the 6th step, the back of granulating is dry, and baking temperature is 105 ℃～115 ℃, drying time 15～25min; Cooling then, the cooling blower electric current is 31A, packing.

Below adopt embodiment to specify embodiment of the present invention, how the application technology means solve technical problem to the present invention whereby, and the implementation procedure of reaching technique effect can make much of and implement according to this.

Embodiment 1 Chinese medicine composition of the present invention is to the toxicity test of duckling

1. trial drug

16g oriental wormwood, 50g yncaria stem with hooks, 23g is windproof, 20g schizonepeta, 45g rhizoma Gastrodiae, 14g safflower, 25g citron, 21g iron holly bark, 16g Sculellaria barbata, 13g reed rhizome, 25g pipewort, the 32g capsule of weeping forsythia, 30g spread out sackcloth, 12g levisticum, 17g Radix Codonopsis, 15g Chinese yam and mix, and are ground into powder; To obtain to soak 36 hours in the powder adding 1200g cold water, with slow fire boiling, decocting time is 1 hour, and decoction liquor is filtered, and obtains first filtrating; Add once more in the 1200g cold water filtering the filter residue that obtains,, filter and obtain second filtrating with slow fire boiling 2 hours; Merge filtrating twice, decompression concentrates and removes part water, obtains said oral liquid, and the crude drug concentration of said oral liquid is 3g/ml.

2. test method

Select the SD rat for use; Give variable concentrations (18.0,6.0, the Chinese medicine preparation oral liquid of the present invention of 2.0g crude drug/kg), irritate stomach every day once, continuous 90 days; Respectively organized 1/2 animal (male and female half and half) extremely that lives in 24 hours after the last administration, all the other 1/2 animals continuation observation, 2 all backs are extremely alive.Duration of test is observed outward appearance, general behavior, food ration, the changes of weight of animal, after the administration 90 days with carry out hematology (RBC, HB, granulophilocyte, PLT, CT, WBC and classification) in 2 weeks of drug withdrawal and check with indexs such as blood biochemical (AST, ALT, ALP, Glu, BUN, Crca, TP, T.BIL, ALB, CHOL), urine biochemistry, organ coefficient, Histopathology.Result of the test shows: Chinese medicine preparation of the present invention is good at high, medium and low dose groups animal general state, all no abnormal variation of outward appearance sign, behavioral activity, food-intake and body weight gain; Three dose groups and control group hematological examination, blood biochemical are learned, the urine biochemical analysis is all in normal range (NR), do not have significant difference between group; Each is organized the main organs histopathological examination and is not seen obviously unusual.The These parameters drug withdrawal is not seen change after 2 weeks yet.This test dosage is respectively 180,60,20 times of clinical medicine dose; According to result of the test Chinese medicine preparation of the present invention high, medium and low three dosage (18.0,6.0, the 2.0g crude drug/kg) administration in continuous 90 days does not have obvious influence to rat; No clear and definite toxicity target organ and sensitive indicator; The retardance toxic reaction is not seen in the convalescence observation yet, points out the dosage safety property of Chinese medicine preparation clinical practice of the present invention higher.

The preparation of embodiment 2 Chinese medicine composition oral liquids

16g oriental wormwood, 50g yncaria stem with hooks, 23g is windproof, 20g schizonepeta, 45g rhizoma Gastrodiae, 14g safflower, 25g citron, 21g iron holly bark, 16g Sculellaria barbata, 13g reed rhizome, 25g pipewort, the 32g capsule of weeping forsythia, 30g spread out sackcloth, 12g levisticum, 17g Radix Codonopsis, 15g Chinese yam and mix, and are ground into powder; To obtain to soak 36 hours in the powder adding 1200g cold water, with slow fire boiling, decocting time is 1 hour, and decoction liquor is filtered, and obtains first filtrating; Add once more in the 1200g cold water filtering the filter residue that obtains,, filter and obtain second filtrating with slow fire boiling 2 hours; Merge filtrating twice, decompression concentrates and removes part water, obtains said oral liquid, and the crude drug concentration of said oral liquid is 3g/ml.

The preparation of embodiment 3 Chinese traditional medicine composition composition injections

13g oriental wormwood, 45g yncaria stem with hooks, 20g is windproof, 17g schizonepeta, 40g rhizoma Gastrodiae, 11g safflower, 22g citron, 19g iron holly bark, 14g Sculellaria barbata, 12g reed rhizome, 22g pipewort, the 30g capsule of weeping forsythia, 27g spread out sackcloth, 10g levisticum, 15g Radix Codonopsis, 13g Chinese yam and mix and pulverize; Add the 1300g decocting and boil 3 times, each decocting time is 2 hours, merges decoction liquor; Filter; Filtrating is concentrated into syrupy shape, adds determining alcohol and be 95% ethanol 350g, left standstill 12 hours; Centrifugal filtration, filtrating is adjusted to filtrating pH7 with 50% NaOH; Filtrating with obtaining adds 0.5% active carbon and boiled 20 minutes, filters, and decarburization adds the injection water, and the crude drug concentration that makes parenteral solution is 3g/ml, and can was sterilized 2 hours in the 500ml saline bottle, after freezing a couple of days, filters.

The preparation of embodiment 4 feeds

16g oriental wormwood, 50g yncaria stem with hooks, 23g is windproof, 20g schizonepeta, 45g rhizoma Gastrodiae, 14g safflower, 25g citron, 21g iron holly bark, 16g Sculellaria barbata, 13g reed rhizome, 25g pipewort, the 32g capsule of weeping forsythia, 30g spread out sackcloth, 12g levisticum, 17g Radix Codonopsis, 15g Chinese yam and mix; Grind to form 100 order fine powders, be prepared into said Chinese medicine additive; Get protein content and account for water that feed adhesive that 20% flour 300g, cornstarch 500g, ammonium sulfate 20g, sodium carbonate 30g, sodium acid carbonate 30g constitute adds 1000g and begin modifiedly, refining temperature is 65 ℃, pours in the spraying machine after stirring; The 9kg wheat is pulverized, and grinding particle size is 500mm, makes its fine powder amount reach 95% of total material; Wheat after pulverizing is poured in the spraying machine, mixed with feed adhesive after modified, water temperature is modulated at 70 ℃ in the spraying machine, opens sprayer, stirs 3 minutes, and it is expanded to continue to be warming up to 90 ℃ of completion; Pulverize expanded product, add the Chinese medicine additive that obtains again, after the mixing, add the water of 900g, put into granulator and granulate, the granulator electric current is 175A; The back of granulating is dry, and baking temperature is 115 ℃, drying time 25min; Cooling then, the cooling blower electric current is 31A, obtains feed.

Clinical trial

1.1 supply the examination material

1.1.1 supply the examination animal

3 ages in days and 7 ages in days do not have Mianyang duckling of maternal antibody available from duck stock breeding center, Mianyang

1.1.2 supply the prelibation strain

Duck hepatitis AV IZ111 strain is provided by China Veterinery Drug Inspection Office

1.1.3 medicine

The traditional Chinese medicine oral liquid of the present invention of embodiment 2 preparations, crude drug amount 3g/mL, the Western medicine amantadine is provided by Jiangsu Bei Kang medicine company, processes the oral liquid that amantadine content is 0. 2 mg/mL.

1.2 test method

1.2.1 test is divided into groups

2 batches of ducklings, are used for viral lethal dose and measure by the 1st batch 100.The 2nd batch 600, be divided into 4 groups, 150 every group, i.e. treatment by Chinese herbs group, western medicine group, infection control group, blank group.

1.2.2 minimum lethal dose is measured

With 100 of ducklings, raise to the 7th day, be divided into 5 groups at random, use DHV allantoic fluid to carry out minimum lethal dose mensuration through the rejuvenation of chicken embryo.Result of the test: minimum lethal dose is 100 times of dilutions of every oral 0. 2 mL allantoic fluids of duckling.

1.2.3 inoculation test

Do not have the maternal antibody duckling with 7 ages in days, measure the result according to lethal dose and carry out formal inoculation test.The blank group is the virus inoculation allantoic fluid not, and all the other respectively organize 1: 100 dilution 0. 2 mL of oral minimum lethal dose virus allantois.The treatment by Chinese herbs group is treated with traditional Chinese medicine oral liquid when symptom occurring at virus inoculation the 3rd day (10 age in days), each oral 1 mL, 1 time/day, logotype 7 days; The western medicine group is used the amantadine oral liquid treatment at virus inoculation the 3rd day (10 age in days) when symptom occurring, each oral 1 mL, 1 time/day, logotype 7 days; The blank group, infecting control group need not any chemoprophylaxis and treatment.

1.2.4 observed and recorded

Attack the poison back and observe clinical symptoms and the pathological change of respectively organizing duck, and compare its order of severity, record death toll, survival number, each group the time (being incubation period) that symptom experiences occurs after attacking poison.Observe to attacking poison and finish after 11 days.

2 results

2.1 the incidence of disease, the death rate and survival change

Blank group duck is all normal, death occurs, and infection control group duck is attacked poison and symptom occurs after 3 days, and is all dead to the 8th day.143 of treatment by Chinese herbs group survivals, 88 of western medicine group survivals.The death rate and survival rate aspect, Chinese medicine compound prescription oral liquid group and Western medicine amantadine group comparing difference are remarkable.Explain that the Chinese medicine compound prescription oral liquid is superior to the Western medicine amantadine to the therapeutic action of duck virus hepatitis.Concrete outcome is seen shown in the table 1.

The incidence of disease, the death rate and the survival rate of each test group of table 1 Chinese medicine compound prescription oral liquid control duck virus hepatitis test are relatively

Annotate: represent and infect control group comparing difference significantly (P < 0. 05) with mark * behind the column of figure; Represent and infect the poor heteropole of control group significantly (P < 0. 01) with mark * * behind the column of figure.

2.2 attack poison back symptom and cut open the inspection result

Sick duck finding symptom is: spirit is depressed, is slow in action, and appetite descends gradually, and feather is thick disorderly unglazed, instability of gait; Squat or lie on one's side, the shake of two limbs paroxysmal occurs and twitches, expiratory dyspnea; Diarrhoea, row yellow or celadon loose stool, on one's deathbed before, be the opisthotonos posture.All attacking poisoned the disease duck that dies with poison and analysed at any time and observe, and pathology mainly shows as: the liver enlargement, and khaki, there are blutpunkte and blood spots in the surface, and serious to be brush strong hemorrhage, also has necrosis region, gall-bladder enlargement individually; Spleen enlargement, surface have the mottling decorative pattern; The kidney enlargement has dendroid congested.It is light that the pathology of medication group duck infects control group.

For example: September in 2010, Quyuan county on the 13rd Lee fed 800 ill seeking medical advice of hybridization duck.Disease is seen down in spirits, the neck cripetura, and falling down to the ground of having lain on one's side, and head presents " back of the body neck " shape to layback.Two leg spasm are kicked at random repeatedly, like the swimming shape.Sometimes rotation on the ground.Occur after the symptom often in death in several minutes to several hours.Cut open inspection: the liver enlargement is prone to crisp, and there is blutpunkte or the blood spots that differs in size on the liver surface.The gall-bladder enlargement, bile is thin out.The spleen enlargement is mottled, the kidney enlargement, and blood vessel is the mulberry dendroid.According to clinical symptoms with cut open the inspection situation, examine and be duck virus hepatitis.All ducks are pressed the feed of feeding embodiment 4,7 days one courses of treatment, 3 courses of treatment of logotype, final dead 12, cures 788, cure rate is 98.5%, follows up a case by regular visits to so far to recur.

This intellectual property of primary enforcement that all are above-mentioned is not set restriction this new product of other forms of enforcement and/or new method.Those skilled in the art will utilize this important information, and foregoing is revised, to realize similar implementation status.But all modifications or transformation belong to the right of reservation based on new product of the present invention.

The above only is preferred embodiment of the present invention, is not to be the restriction of the present invention being made other form, and any professional and technical personnel of being familiar with possibly utilize the technology contents of above-mentioned announcement to change or be modified as the equivalent embodiment of equivalent variations.But everyly do not break away from technical scheme content of the present invention, to any simple modification, equivalent variations and remodeling that above embodiment did, still belong to the protection domain of technical scheme of the present invention according to technical spirit of the present invention.

Claims (10)

1. feed; It is characterized in that; Comprise: be used to treat the Chinese medicine composition and the feed vector of duck virus hepatitis, said Chinese medicine composition further comprises oriental wormwood, yncaria stem with hooks, windproof, schizonepeta, rhizoma Gastrodiae, safflower, citron, iron holly bark, Sculellaria barbata, reed rhizome, pipewort, the capsule of weeping forsythia, Folium Apocyni Veneti, levisticum, Radix Codonopsis and Chinese yam.

2. feed as claimed in claim 1; It is characterized in that: the ratio of weight and number of each component in the said Chinese medicine composition does, oriental wormwood 10～16 weight portions, yncaria stem with hooks 40～50 weight portions, windproof 18～23 weight portions, schizonepeta 15～20 weight portions, rhizoma Gastrodiae 35～45 weight portions, safflower 8～14 weight portions, citron 20～25 weight portions, iron holly bark 17～21 weight portions, Sculellaria barbata 12～16 weight portions, reed rhizome 10～13 weight portions, pipewort 20～25 weight portions, the capsule of weeping forsythia 27～32 weight portions, spreads out sackcloth 25～30 weight portions, levisticum 8～12 weight portions, Radix Codonopsis 13～17 weight portions, Chinese yam 11～15 weight portions.

3. according to claim 1 or claim 2 feed; It is characterized in that: the ratio of weight and number of each component in the said Chinese medicine composition does, oriental wormwood 13～16 weight portions, yncaria stem with hooks 45～50 weight portions, windproof 20～23 weight portions, schizonepeta 17～20 weight portions, rhizoma Gastrodiae 40～45 weight portions, safflower 11～14 weight portions, citron 22～25 weight portions, iron holly bark 19～21 weight portions, Sculellaria barbata 14～16 weight portions, reed rhizome 12～13 weight portions, pipewort 22～25 weight portions, the capsule of weeping forsythia 30～32 weight portions, spreads out sackcloth 27～30 weight portions, levisticum 10～12 weight portions, Radix Codonopsis 15～17 weight portions, Chinese yam 13～15 weight portions.

4. like the described feed of claim 1 to 3; It is characterized in that: the said Chinese medicine composition that is used for treating duck virus hepatitis can also comprise the hawthorn and the membrane of a chicken's gizzard; The said hawthorn and the membrane of a chicken's gizzard ratio of weight and number in said Chinese medicine composition is hawthorn 3～5 weight portions, the membrane of a chicken's gizzard 1～3 weight portion.

5. like the described feed of claim 1 to 4, it is characterized in that: the ratio of weight and number of said feed vector and said Chinese medicine composition additive can be 100 weight portions: 1～5 weight portion.

6. like the described feed of claim 1 to 5; It is characterized in that: said feed also comprises feed adhesive; The ratio of weight and number of said feed vector and said feed adhesive can be 100 weight portions: 10～20 weight portions, comprise Strong flour, starch, ammonium sulfate, sodium carbonate and sodium acid carbonate in the said feed adhesive, and the ratio of weight and number of each composition does in the said feed adhesive; Strong flour is 20 ~ 30 parts, and starch is 30 ~ 50 parts; The gross weight umber ratio of ammonium sulfate, sodium carbonate and sodium acid carbonate is 3 ~ 8 parts; Said starch is preferably cornstarch, and wherein with respect to 100 parts of starch gross weights, farinose ratio of weight and number is 70 ~ 90 parts, and the ratio of weight and number of ripe starch is 10 ~ 20 parts; Said Strong flour is the protein wt degree greater than 13.5% flour.

7. the preparation method of the described feed of claim 1 to 6 is characterized in that, said Chinese medicine composition is prepared from through following method:

The first step; Said oriental wormwood, yncaria stem with hooks, windproof, schizonepeta, rhizoma Gastrodiae, safflower, citron, iron holly bark, Sculellaria barbata, reed rhizome, pipewort, the capsule of weeping forsythia, Folium Apocyni Veneti, levisticum, Radix Codonopsis and Chinese yam are ground to form 100～200 order fine powders by said mixed, be prepared into said Chinese medicine additive;

Second the step, feed adhesive is added in proportion, with respect to the feed adhesive of 100 weight portions, in the water of 15～30 weight portions the beginning modified, refining temperature is 62 ~ 68 ℃, pours in the spraying machine after stirring;

In the 3rd step, said feed vector is pulverized, and grinding particle size is 300～550mm, makes its fine powder amount reach more than 92% of total material;

In the 4th step, the feed vector after said the 3rd step pulverized is poured in the spraying machine, mixes with feed adhesive after modified, and water temperature is modulated at 60～70 ℃ in the spraying machine, opens sprayer, stirs 1 minute～3 minutes, and it is expanded to continue to be warming up to 90 ℃ of completion;

The 5th step, pulverize expanded product, add the Chinese medicine additive that the first step obtains again, after the mixing, add water with respect to 1 ~ 10 part of the parts by weight of the mixture of 100 weight portions, to put into granulator and granulate, the granulator electric current is 175A～195A;

In the 6th step, the back of granulating is dry, and baking temperature is 105 ℃～115 ℃, drying time 15～25min; Cooling then, the cooling blower electric current is 31A, packing.

8. a parenteral solution is characterized in that, comprising: oriental wormwood, yncaria stem with hooks, windproof, schizonepeta, rhizoma Gastrodiae, safflower, citron, iron holly bark, Sculellaria barbata, reed rhizome, pipewort, the capsule of weeping forsythia, Folium Apocyni Veneti, levisticum, Radix Codonopsis and Chinese yam.

9. parenteral solution as claimed in claim 8; It is characterized in that: the weight fraction of each component ratio does in the said parenteral solution, oriental wormwood 10～16 weight portions, yncaria stem with hooks 40～50 weight portions, windproof 18～23 weight portions, schizonepeta 15～20 weight portions, rhizoma Gastrodiae 35～45 weight portions, safflower 8～14 weight portions, citron 20～25 weight portions, iron holly bark 17～21 weight portions, Sculellaria barbata 12～16 weight portions, reed rhizome 10～13 weight portions, pipewort 20～25 weight portions, the capsule of weeping forsythia 27～32 weight portions, spreads out sackcloth 25～30 weight portions, levisticum 8～12 weight portions, Radix Codonopsis 13～17 weight portions, Chinese yam 11～15 weight portions.

10. the preparation method of claim 8 or 9 parenteral solution is characterized in that, comprising:

The first step is mixed pulverizing, boiling 2～4 times in proportion with oriental wormwood, yncaria stem with hooks, windproof, schizonepeta, rhizoma Gastrodiae, safflower, citron, iron holly bark, Sculellaria barbata, reed rhizome, pipewort, the capsule of weeping forsythia, Folium Apocyni Veneti, levisticum, Radix Codonopsis and Chinese yam; Each decocting time is 2 hours～3 hours, and the quality of adding is 2～4 times of first step mixture quality, merges decoction liquor; Filter, filtrating is concentrated into syrupy shape, adding determining alcohol is the ethanol more than 95%; The ethanol content that adds is 1～2 times of mixture quality of the first step; After leaving standstill 12 hours～24 hours, centrifugal filtration, filtrating is adjusted to filtrating pH7～8 with 40%～50% NaOH;

In second step, the filtrating with the first step obtains adds 0.5%～1% active carbon and boiled 18～22 minutes, filters; Decarburization adds the injection water, and the crude drug concentration that makes parenteral solution is 2g/ml～4g/ml; Can was sterilized in the 500ml saline bottle 1.5 hours～2 hours, after freezing a couple of days, filtered.