CN104256165A - Functional feed for preventing and treating chronic swine plague and preparation method of functional feed - Google Patents

Abstract

The invention discloses a functional compound feed for preventing and treating chronic swine plague and a preparation method of the functional feed. The functional feed comprises the following raw materials: wheat bran, corns, wheat, lotus root starch, millet, kelp, asparagus, grapefruits, Chinese wax gourd peels, edible amaranth, soybean meal, tomatoes, loofah, lotus seeds, oyster mushrooms, vitamin premix and microelement premix. The functional compound feed disclosed by the invention has the beneficial effects of containing the traditional Chinese medicine additives for clearing away heat and toxic materials, cooling blood and promoting the secretion of saliva or body fluid, being used for strengthening the body resistance to eliminate pathogenic factors and having the advantages of relatively short course of treatment, relatively good course of treatment, no drug residue, low cost and price and the like; the functional feed has the capabilities of enhancing the immunity and disease resistance of swine while achieving harmony between yin and yang as well as qi and blood of the swine, short course of treatment, relatively good effect and low residual mount, and is environmentally friendly and is free of pollution.

Description

For preventing and treating functional feed of chronic type swine fever epidemic disease and preparation method thereof

Technical field

The present invention relates to bird feed, particularly a kind of functional collaboration feed for preventing and treating chronic type swine fever epidemic disease and preparation method thereof.

Background technology

Swine fever is a kind of hyperinfection and lethal epidemic disease that are caused by CSFV, it is characterized by high heat and delays extensively hemorrhage, the infraction that causes with thin vessels sex change and downright bad.The pig premunition of infected pigs's pestivirus reduces, very easily concurrent or secondary swine plague.Especially cold, moist, cold and heat succeed each other, weather drastic change, under the bad condition such as crowded, improper ventilation, pig body resistance reduced, Pasteurella amount reproduction can be caused, virulence enhancing and falling ill, as controlled not in time, the large quantities of death of pig can be caused.

The sick pig spirit of clinical symptoms is depressed, and body temperature is elevated to 40 DEG C ~ 41.5 DEG C.In continued fever, anorexia is even absolutely useless, and eye flows dense sexual secretion.Visual mucous membrane cyanosis.Sick just constipation, after have loose bowels, stench band blood is also mixed with white mucous membrane.Whole body is rubescent, and have sharp ears, belly, neck and limbs skin have purple plague purpura, and finger pressure does not fade.Boar foreskin has muddy urine, and neck swelling is hard, the sensitivity touched.Sick pig cough, expiratory dyspnea, calls hoarse, and nose flows out serosity or sticky secretion, indivedual hog snout holes elution band bleeding blister foam, and serious is the mouth breathing of dog sitting posture, eventually because of death by suffocation.Inspection sick dead pig is cutd open in pathological change altogether, pathological change basic simlarity, and lymph nodes of body as a whole enlargement is hemorrhage, in kermesinus; Stomach bottom mucous membrane, bladder mucosa are hemorrhage; Spleen surface has the hemorrhage infarct of the hemorrhage and mung bean size mulberry of mound shape point, and there is needle point massive haemorrhage point on surface; Ileocaecal sphineter, caecum and colonic mucosa have button-type ulcer; Larynx has blood spots and blutpunkte; Heart hat fat, the internal membrane of heart have blutpunkte; Pulmonary edema is furvous, and has the pneumonia stove not of uniform size be dispersed in; Have mucus blister secretion in trachea-bronchial epithelial cell, and be mixed with quantity not wait courageous and upright foam; Thoracic cavity and pericardium amass the pink turbid liquid of volume; Neck subcutaneous dropsy, flush, extravasated blood.

Pestilence is early on the books in Chinese historical data.As " all gift heavenly officials tombs are killed " is recorded: " physician slaps the disease of foster ten thousand people, all has pestilence disease when four." " Springs and Autumns of Master Lü last month of spring discipline " record: " summer weather in spring in season, the then people's many diseases epidemic disease." illustrate and at that time certain level is reached to the understanding of pestilence, think that warm epidemic disease all can occur throughout the year, one of reason is gas abnormal due to season, is caused by " gas time non-".The Chinese medical book Huangdi's Internal Classics of earliest extant is also on the books.As " Plain Questions acupuncture manipulation opinion " points out: " five epidemic diseases extremely, all to dye easily, without asking size, symptom is similar ..., in healthy tendency is deposited, heresy can not be done, preventing the invasion of infectious pathogen." " Plain Questions instinct sick " section: " and the moon of fainting is not given up the throne, and namely strong wind is early lifted, time rain do not fall, wet order is not changed, and the sick warm epidemic disease of the people, defect gives up.Humorously, people's disease is the arthrodynia of extremeties, head's pain all, and tired in latent heat, throat is dry draws drink." point out that warm epidemic disease has the features such as infectiousness, popularity, clinical manifestation are similar, morbidity is relevant with weather, as long as and think " healthy tendency deposit in ", with regard to energy " preventing the invasion of infectious pathogen ".

Adopt Western medicine to prevent and treat this disease and mostly adopt antibiotic, occurred and had increasing trend to the bacterial strain that these medicines develop immunity to drugs, in addition, these chemicalses obviously can cause pig drug disposition to remain, and then affect human and livestock health and even endanger public health.Western medical treatment swine fever epidemic disease course for the treatment of is longer, the undesirable epidemic situation of effect is wayward, can cause very large economic loss.

But China's traditional Chinese medicine and pharmacy just had understanding to pestilence (infectious disease) before 2 over thousands of years, and propose reasonably to take precautions against and treatment, as the Zhou Dynasty " Book of Rites. month " record " the row autumn first month of spring is the sick large epidemic disease of the people then ", " the asking that size symptom is similar to nothing to all passing on from one to another of five epidemic diseases " is had clearly to propose infectiousness and the epidemic characteristic of epidemic disease in Huangdi's Internal Classics, the method of sweet wormwood preventing and curing malaria disease is the medicine dedicated of antimalarial in the world by generally acknowledging in the world so far in addition, in conjunction with in current " first stream " control, health ministry clearly proposes traditional Chinese medicine and participates in control prece and more demonstrate China's Chinese Traditional Medicine and preventing and treating the importance and functions in pestilence.

The incubation period of natural infection swine fever is generally 5-7 d, and that short is 2 d, and long reaches 21 d.According to the state of an illness and the course of disease, often in clinical symptoms swine fever is divided into most acute, acute, chronic type and delayed.

1, most acute is more common in the popular initial stage, sudden onset, and symptom sharply, performance general spasticity, tic of limbs, delay, skin and mucous membrane cyanosis, has hemorrhage spot, dead through 1-8 days by high heat.2, acute.This kind of is the most common.In sick pig before there is symptom, namely body temperature raised at 41 degrees centigrade, persistent, show as slow in action, end to end sagging, hogback, shiver, thirsty, a normal sleeping place is drowsiness, the inflammation of eye conjunctiva, the puffiness of the eyes, secretion increase, and can see purple red color spot point at places such as lower abdomen, the basal part of the ear, four hoof, lip, vulvas.Sick difficulty of just discharging feces, occur diarrhoea soon, ight soil is lark.Boar foreskin inner product has urine, flows out muddy canescence stench liquid with after hand extruding.Also can there is acute swine fever in suckling pig, main manifestations nervous symptoms, as ground one's teeth in sleep, spasm, opisthotonos or the tic that falls down to the ground, finally dead.3, chronic type.Main manifestations is become thin, anaemia, and asthenia universalis is often lain prostrate, and gait is slowly unable, poor appetite, and constipation and diarrhoea are alternately.The sick pig had has purple plague purpura or downright bad scab on ear end, tail point and limbs skin.The course of disease more than one month.Died long term development is not bad becomes cad pig.Virus may be passed to fetus by placenta, cause miscarriage after infecting by in-pig, occurs diarrhoea after producing stillborn foetus or the small and weak piglet of output or wean.4, mild.PD is slow, sick temperature of pig body generally at 40-41 degrees Celsius, skin often without hemorrhage point, but in the common hemostasis of hypogastrium and necrosis.Sometimes visible ear and tail skin necrosis, paddy claims dry ear, dry tail.The course of disease reaches 2-3 month.

Summary of the invention

Technical problem to be solved by this invention is the functional feed being to provide a kind of Chinese medicine additive for preventing and treating chronic type swine fever epidemic disease, the Feed Energy containing this Chinese medicine additive is adopted to overcome the various defects of Chinese medicine of the prior art and Western medicine, to the treatment of the pig suffering from swine fever epidemic disease, there is clearing heat and detoxicating, cool blood to promote the production of body fluid, pig yang blood and qi is in harmonious proportion, treatment short treating period, effect is better, residual quantity low while can strengthen the immunity of pig and see resistance against diseases, green non-pollution.

In order to realize foregoing invention object, the invention provides a kind of functional collaboration feed for preventing and treating chronic type swine fever epidemic disease, described feed comprises following raw material: wheat bran, corn, wheat, lotus root starch, millet, sea-tangle, asparagus, grapefruit, waxgourd peel, three-coloured amaranth, dregs of beans, tomato, sponge gourd, lotus seeds, flat mushroom, vitamin premix and microelement pre-mix material.

In described feed, the parts by weight of each raw material are: wheat bran 40-65 weight portion, corn 25-45 weight portion, wheat 20-32 weight portion, millet 20-28 weight portion, lotus root starch 15-30 weight portion, sea-tangle 15-25 weight portion, asparagus 7-14 weight portion, grapefruit 8-17 weight portion, waxgourd peel 15-20 weight portion, three-coloured amaranth 10-19 weight portion, dregs of beans 10-22 weight portion, tomato 15-35 weight portion, sponge gourd 7-16 weight portion, lotus seeds 5-10 weight portion, flat mushroom 4-9 weight portion, vitamin premix 0.3-0.5 weight portion and microelement pre-mix material 0.3-0.5 weight portion.

Described feed also comprises Chinese medicine additive, in described feed, the parts by weight of each raw material are: wheat bran 40-65 weight portion, corn 25-45 weight portion, wheat 20-32 weight portion, millet 20-28 weight portion, lotus root starch 15-30 weight portion, sea-tangle 15-25 weight portion, asparagus 7-14 weight portion, grapefruit 8-17 weight portion, waxgourd peel 15-20 weight portion, three-coloured amaranth 10-19 weight portion, dregs of beans 10-22 weight portion, tomato 15-35 weight portion, sponge gourd 7-16 weight portion, lotus seeds 5-10 weight portion, flat mushroom 4-9 weight portion, vitamin premix 0.3-0.5 weight portion, microelement pre-mix material 0.3-0.5 weight portion and Chinese medicine additive 2-4 weight portion.

In described feed, the parts by weight of each raw material are: wheat bran 65 weight portion, corn 45 weight portion, wheat 28 weight portion, millet 25 weight portion, lotus root starch 19 weight portion, sea-tangle 20 weight portion, asparagus 13 weight portion, grapefruit 15 weight portion, waxgourd peel 17 weight portion, three-coloured amaranth 14 weight portion, dregs of beans 21 weight portion, tomato 30 weight portion, sponge gourd 8 weight portion, lotus seeds 7 weight portion, flat mushroom 6 weight portion, vitamin premix 0.5 weight portion, microelement pre-mix material 0.5 weight portion and Chinese medicine additive 2 weight portion.

Described Chinese medicine additive comprises following raw medicinal material: gypsum rubrum, cape jasmine, the dried rhizome of rehmannia, cacumen biotae, moutan bark, reed rhizome, root of Chinese trichosanthes, lophatherum gracile, dayflower, phoenix-tail fern, pivot store, dandelion, lotus leaf, lotus nut, the tuber of dwarf lilyturf, the capsule of weeping forsythia, radix scrophulariae, Radix Glycyrrhizae, Chinese eriosema root, Dicliptera chinensis, Ying Azulene, Ji Ni, indian melothria root, bastardtoadflaxlike swallowwort herb and fruit, snakegourd, tuberous sword fern tuber, giant clam meat is with Bi Collettii.

In described Chinese medicine additive, the parts by weight of each raw medicinal material are: gypsum rubrum 23-36 part, cape jasmine 7-15 part, dried rhizome of rehmannia 17-35 part, cacumen biotae 25-40 part, moutan bark 9-25 part, reed rhizome 13-27 part, root of Chinese trichosanthes 10-28 part, lophatherum gracile 25-38 part, dayflower 28-40 part, phoenix-tail fern 26-39 part, pivot stores 12-32 part, dandelion 12-37 part, lotus leaf 20-35 part, lotus nut 15-28 part, the tuber of dwarf lilyturf 15-30 part, capsule of weeping forsythia 12-25 part, radix scrophulariae 25-40 part, Radix Glycyrrhizae 15-32 part, Chinese eriosema root 11-23 part, Dicliptera chinensis 17-30 part, Ying Azulene 26-42 part, Ji Ni 3-10 part, indian melothria root 15-29 part, bastardtoadflaxlike swallowwort herb and fruit 20-37 part, snakegourd 7-23 part, tuberous sword fern tuber 11-29 part, giant clam meat 20-38 part is with Bi Collettii 14-29 part.

In described Chinese medicine additive, the parts by weight of each raw medicinal material are: gypsum rubrum 33 parts, cape jasmine 11 parts, 24 parts, the dried rhizome of rehmannia, cacumen biotae 36 parts, moutan bark 19 parts, reed rhizome 21 parts, root of Chinese trichosanthes 12 parts, lophatherum gracile 35 parts, dayflower 29 parts, phoenix-tail fern 38 parts, pivot stores 14 parts, dandelion 25 parts, 32 parts, lotus leaf, lotus nut 17 parts, the tuber of dwarf lilyturf 15 parts, the capsule of weeping forsythia 16 parts, radix scrophulariae 39 parts, 32 parts, Radix Glycyrrhizae, Chinese eriosema root 11 parts, Dicliptera chinensis 30 parts, Ying Azulene 40 parts, Ji Ni 5 parts, indian melothria root 17 parts, bastardtoadflaxlike swallowwort herb and fruit 24 parts, snakegourd 8 parts, tuberous sword fern tuber 17 parts, giant clam meat 35 parts of He Bi Collettii 16 parts.

The preparation method of described Chinese medicine additive comprises the following steps:

The first step, mixes in proportion by described each raw medicinal material, and adding relative to the determining alcohol of mixture quality 2 ~ 4 times is the ethanol of 85 ~ 95%, adds hot reflux 1 ~ 3 hour, extracts, and filters acquisition first extract; Filter the dregs of a decoction obtained to add relative to the determining alcohol of described dregs of a decoction quality 1 ~ 2 times to be again the ethanol of 85 ~ 95%, to add hot reflux 1 ~ 3 hour that acquisition second extract is filtered in extraction; First extract and the second extract are merged, reduced pressure concentration removing alcohol solvent, dry, obtain and get dry extract;

Second step, is placed on the dry cream that the first step obtains in micronizer and pulverizes 1 ~ 2 hour, pulverize, sieve, obtain 300 order ~ 400 object micropowders, obtain Chinese medicine additive powder.

In order to realize goal of the invention better, the present invention also provides a kind of preparation method of the mixed feed for preventing and treating chronic type swine fever epidemic disease, and described preparation method comprises the following steps:

(1) take all Chinese medicine additive mixed grindings according to ratio of weight and number and become 180-250 order fine powder, be prepared into Chinese medicine additive;

(2) get wheat bran, corn, wheat, lotus root starch, millet, sea-tangle, asparagus, grapefruit, waxgourd peel, three-coloured amaranth, dregs of beans, tomato, sponge gourd, lotus seeds, flat mushroom, vitamin premix and microelement pre-mix material in proportion to pulverize, grinding particle size is 300-500mm, and its fine powder amount is reached, and feedstuff always expects more than 97%;

(3) feedstuff after described step (3) being pulverized is poured in spraying machine, and in spray, water temperature is 70-88 DEG C, opens spraying machine, stirs 10-15 minute, continues to be warming up to 98 DEG C and complete expanded;

(4) the expanded product that obtains of pulverising step (3), then the Chinese medicine additive adding that step (1) obtains, obtain mixture, add the water of parts by weight 7-15 part of the mixture relative to 100 weight portions, put into granulator and granulate;

(6) dry after granulating, baking temperature is 105 DEG C ~ 112 DEG C, drying time 30-50min; Then cool, pack.

The invention has the beneficial effects as follows: feed of the present invention contains the Chinese medicine additive with the effect that clearing heat and detoxicating, cool blood promotes the production of body fluid, can strengthening vital QI to eliminate pathogenic factors, there is the course for the treatment of shorter, curative effect is better, drug residue free, the advantages such as cost price is cheap, make pig yang blood and qi be in harmonious proportion, treatment short treating period, effect is better, residual quantity low while can strengthen the immunity of pig and see resistance against diseases, green non-pollution.

Detailed description of the invention

Chinese medicine additive refers to take as the leading factor with the traditional theory of China to the physical property of the Nature Chinese herbal medicine (yin, yang, tremble with fear, freeze, temperature, heat), thing taste (sour, sweet, bitter, peppery, salty) and material relation and with the subjects theory such as raising and feed industry and technology for support, the single and compound Chinese herb feed additive developed or intermixture.From modern pharmacology Epidemiological Analysis, feed addictive based on Chinese herbal medicine effective ingredients, there is the immunologic function and non-specific antimicrobial effect that regulate body, Chinese herbal medicine contains alkaloid, polysaccharide, two class volatile oil, the bioactivator such as organic acid flavones and bioflavonoid of anti-antibacterial composition, to adjustment human body immune function, good effect of improving health conditions.It is reported, ward off more and there is the reaction of promotion thymus gland, stimulation reticuloendothelial cell raising specific antigen respond; Alkaloid can strengthen body fluid and cellular immune function, and the phagocytic function of stimulating expression of macrophage, two classes can strengthen the phagocytic function of reticuloendothelial system, and can generate by enhancing antibody, promote antigen-antibody reaction and lymphocyte transformation organic acid, intestines can be regulated interior and prevent the breeding of harmful bacteria and improve the activity of enzyme, animal body intracellular metabolic can normally be carried out.The nutriment of folding Chinese herbal feed additive not only containing some is divided from the theory of modern nutriology, but also contain unknown growth regulator and the pigment of some, there is the biochemical reaction activating body directly or indirectly, strengthen biosynthesis effect, thus promote the production performance of animal.

Chinese medicine additive of the present invention is mainly theoretical according to traditional Chinese medical science strengthening vital QI to eliminate pathogenic factors, theory of traditional Chinese medical science think righting and eliminating evil be two aspects connected each other, righting is in order to eliminating evil, by strengthening the method for healthy tendency, get rid of evils and go out, thus get well, be i.e. so-called " just containing evil in dispelling ".Eliminating evil is in order to righting, eliminates the infringement of paathogenic factor and reaches protection healthy tendency, restorative object, i.e. so-called " heresy is gone just from peace ".Righting and eliminating evil be complementary two aspects.When therefore using the rules for the treatment of of strengthening vital QI to eliminate pathogenic factors, conscientiously to carefully analyze the contrast situation of good and evil strength, know the secondary from the primary, determine righting or eliminating evil, or determine the priority of strengthening vital QI to eliminate pathogenic factors.Generally, righting is used for asthenic symptoms; Eliminating evil for real example; If belong to mixture of asthenia and sthenia card, then answer strengthening vital QI to eliminate pathogenic factors and use, but this taking into account not being righting and eliminating evil half and half, is the primary and secondary emergency will distinguishing actual situation, to determine the primary and secondary, successively of strengthening vital QI to eliminate pathogenic factors.In a word, should with " righting is unlikely stays heresy, eliminating evil just do not causing injury " for degree.

Chinese medicine additive of the present invention follows the general principle of " strengthening vital QI to eliminate pathogenic factors ", follow clearing heat and detoxicating, the principle that cool blood promotes the production of body fluid, provide a kind of feed for preventing and treating chronic type swine fever epidemic disease, it comprises Chinese medicine additive, Chinese medicine additive comprises following raw medicinal material: gypsum rubrum, cape jasmine, the dried rhizome of rehmannia, cacumen biotae, moutan bark, reed rhizome, root of Chinese trichosanthes, lophatherum gracile, dayflower, phoenix-tail fern, pivot stores, dandelion, lotus leaf, lotus nut, the tuber of dwarf lilyturf, the capsule of weeping forsythia, radix scrophulariae, Radix Glycyrrhizae, Chinese eriosema root, Dicliptera chinensis, Ying Azulene, Ji Ni, indian melothria root, bastardtoadflaxlike swallowwort herb and fruit, snakegourd, tuberous sword fern tuber, giant clam meat is with Bi Collettii.Wherein, gypsum rubrum clearing heat-fire; Cape jasmine, Chinese eriosema root, Dicliptera chinensis, Ying Azulene, Ji Ni, indian melothria root, bastardtoadflaxlike swallowwort herb and fruit, snakegourd, tuberous sword fern tuber, giant clam meat, can cooling blood and hemostasis, clearing heat and detoxicating with the dried rhizome of rehmannia, radix scrophulariae, cacumen biotae, moutan bark etc. with Bi Collettii, with controlling blood-heat bleeding; Root of Chinese trichosanthes clearing heat and promoting fluid, detumescence and apocenosis, for diseases such as consumption of body fluid caused by febrile disease, the tuber of dwarf lilyturf, the capsule of weeping forsythia, dandelion are with using; Lophatherum gracile and the dried rhizome of rehmannia, Radix Glycyrrhizae, reed rhizome etc. are for clearing away heart-fire; Dayflower one medicine, is longer than heat-clearing, again can diuresis, and phoenix-tail fern, pivot stores, dandelion is equivalent uses; Wherein, dayflower and lophatherum gracile can reducing fever and causing diuresis, and effect is similar, but the effect of dayflower is stronger.Lotus leaf this product bitter is put down, and its gas is fragrant clearly, can clearing away summerheat, can rise again and send out spleen sun, hemostasis; Lotus nut is bitter, cold, enters the heart channel of Hang-Shaoyin.

The pharmacological property of above-mentioned each raw medicinal material is as follows:

Gypsum rubrum: pungent, salty, cold; The thoughts of returning home, stomach, kidney channel.Row pyreticosis when curing mainly, high fever polydipsia, abscess of throat, oedema, renal shutdown, aphthae, ulcer, erysipelas, scalds.

Cape jasmine: bitter, cold, nontoxic; Thoughts of returning home warp, Liver Channel, lung channel, stomach warp, tri-jiao channel.Cure mainly the red pain of order heat, the large heat of chest heart intestine and small intestine, unhappy in the heart, pathogenic heat in the stomach gas.Purging intense heat relieving restlessness, clearing heat and promoting diuresis, removing pattogenic heat from the blood and toxic material from the body, cooling blood and hemostasis.Pyreticosis is vexed, irascibility hot eyes, and headache, jaundice with damp-heat pathogen, stranguria, bloody flux hematuria, aphthae, sore swollen toxin, sprains and swell and ache.

The dried rhizome of rehmannia: sweet, cold; The thoughts of returning home, liver, kidney channel.Heat-clearing, promote the production of body fluid, moisturize, laxation, the broken stasis of blood, raw new, pain relieving, menstruation regulating, cool blood, hemostasis invigorate blood circulation.

Cacumen biotae: bitter, puckery, cold.Return lung, liver, the spleen channel.Cooling blood and hemostasis, growing and blacking hair.For hematemesis and epistaxis, spitting of blood, has blood in stool, metrostaxis, blood-head alopecia, poliosis.

Moutan bark: bitter, pungent, cold nature, the thoughts of returning home, liver, kidney channel.There is the effect of clearing heat and cooling blood, promoting blood circulation to remove blood stasis.

Reed rhizome: sweet, cold; Return lung channel, stomach warp.Clearing heat and promoting fluid, relieving restlessness, preventing or arresting vomiting, diuresis.Cure mainly: drench puckery pain for pyreticosis polydipsia, gastropyretic vomiting, cough with lung heat, lung carbuncle pyemesis, heat.Reed rhizome is used for gastropyretic vomiting.

Root of Chinese trichosanthes: sweet, micro-hardship, is slightly cold; Attach to the lung and stomach meridians.Clearing heat and promoting fluid, detumescence and apocenosis.For pyreticosis polydipsia, lung-heat type cough, interior heat is quenched one's thirst, sore swollen toxin.

Lophatherum gracile: sweet, light, cold.The thoughts of returning home, stomach, small intestinl channel.Clearing heat and relieving fidgetness, diuresis.For pyreticosis polydipsia, hot urination drenches pain, aphthae.

Dayflower: sweet, cold, light; The thoughts of returning home, all warps of liver,spleen,kidney, intestine and small intestine.Main fever and chills malignant malaria, phlegm and retained fluid, fourth swells, and meat disease is not smooth, infantile erysipelas, mad epilepsy of generating heat, and large abdomen ruffian is full, and body face wind-puff, hot dysentery, dog stings snake, the poison such as ulcer.For fever caused by exogenous pathogens, or febrile disease heating is not moved back, or abscess of throat, and carbuncle swells the diseases such as sore.For difficult urination, oedema, or wet into diseases such as bet bladder, the puckery pains of dribbling urination.

Phoenix-tail fern: light, micro-hardship is cool.Heat-clearing, dampness removing, cool blood.Control bacillary dysentery, enteritis, fever caused by exogenous pathogens, urinary tract infections, leukorrhea, mumps, furunculosis, eczema." clearing heat and promoting diuresis, removing toxic substances is dysentery only, cooling blood and hemostasis.For dysentery, gastroenteritis, hepatitis, urinary infection, cat fever, abscess of throat, leukorrhea, uterine bleeding, pesticide poisoning; Traumatism and bleeding is controlled in external application, burn and scald.

Pivot stores: bitter, cold; Return urinary bladder channel.Diuresis, heat-clearing, desinsection.Cure mainly and control heat pouring, the retention of urine, jaundice, the erosion of vulva, leukorrhea, roundworm, infantile malnutrition due to digestive disturbances or intestinalparasites, hemorrhoid swell, wet sore.

Dandelion: nature and flavor are sweet, micro-hardship, cold; Return spleen, stomach, kidney three warp.Apply all pyogenic infections from tumour or sore, the ruined tinea sore of scabies; Dispel the wind, disappear all sores, loose scrofula tuberculosis; Stop little having blood in stool, control the five pouring retention of urines, sharp bladder.Clearing heat and detoxicating, the carbuncle that disappears dissipating bind.Can be used for the infection of the upper respiratory tract, eye conjunctivitis, mumps, hyperglycaemia, acute mastitis swells and ache, gastritis, dysentery, hepatitis, cholecystitis, acute appendicitis, urinary infection, pelvic infecton, carbuncle furuncle furunculosis, pharyngitis, controls acute mastitis, adenolymphitis, scrofula, malignant boil carbuncle toxin, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, urinary tract infections.

Lotus leaf: bitter is pungent micro-puckery, cool in nature; The thoughts of returning home, liver, the spleen channel.Cure mainly hot summer weather polydipsia, have a headache dizzy, oedema, the few abdominal distension of food, rush down dysentery, leukorrhea, prolapse of the anus, spit blood, bleeding from five sense organs or subcutaneous tissue, spitting of blood, has blood in stool, uterine bleeding, post partum longtime lochia, traumatic blood stasis.

Lotus nut: bitter, cold, nontoxic; The thoughts of returning home, lung, kidney three warp.Clearing away the heart-fire, flat irascibility, rushes down spleen fire, falls lung-fire.To relieve summer heat relieving restlessness, promote the production of body fluid to quench thirst, control order redness.

The tuber of dwarf lilyturf: sweet, the micro-hardship of property, is slightly cold; The thoughts of returning home, lung, stomach warp.Have nourishing Yin and promoting production of body fluid, effect that moistening lung clears away heart-fire, can be used for larynx numbness pharyngalgia, Tianjin wound is thirsty, and interior heat is quenched one's thirst, vexed insomnia, the dry constipation of intestines etc.

The capsule of weeping forsythia: bitter, cold nature; The thoughts of returning home, lung, small intestinl channel.Cure mainly pyreticosis from the beginning of, anemopyretic cold, heating, vexed, the symptom such as abscess of throat, acute nephritis, carbuncle sore tumefacting virus.

Radix scrophulariae: taste is sweet, bitter, salty, cold nature, returns lung, stomach, kidney channel.There is clearing heat and cooling blood, purging intense heat and detonicating, effect of enriching yin, cure mainly warm heat disease heat and ying blood, body heat, polydipsia, tongue are deep red, a spot, hectic fever due to yin labor are coughed, the cards such as constipation, order puckery dim-sighted, throat larynx swells and ache, scrofula subcutaneous nodule, skin sore are not hindered in awake, Tianjin to dysphoria.

Radix Glycyrrhizae: nature and flavor are sweet, flat; Return spleen, stomach, lung channel.Crymodynia in main abdomen, controls frightened epilepsy, except distention and fullness in the abdomen; Help the five internal organs; Make all medicines poison; Support kidney qi internal injury, make impotence; Housewife's human blood drop pain in the back; Empty and how heat; Add and use it.Can beneficial gas bowl spares, relieving spasm to stop pain, moistens the lung and relieve the cough, purging intense heat and detonicating, coordinating the drug actions of a prescription.

Chinese eriosema root: sweet; Flat.Return lung; Large intestine; Liver Channel.Clearing lung and eliminating phlegm; Promote the production of body fluid to quench thirst; Detumescence.Main cough with lung heat; Lung carbuncle; Heating polydipsia; Dysentery; Hydrocele testis, dyspepsia does not disappear; Treating swelling and pain by traumatic injury.

Dicliptera chinensis: taste is sweet; Micro-hardship; Cold in nature.The thoughts of returning home; Liver; Lung channel.Heat-clearing; Cool blood; Dampness removing; Removing toxic substances.Main cold, fever; Pyreticosis sends out spot; Tell bleeding from five sense organs or subcutaneous tissue; Have blood in stool; Hematuria; Uterine bleeding; Cough with lung heat; Abscess of throat; The hot hot eyes of liver; Child convulsion; Dribbling urination; Under band; Herpes zoster; Carbuncle swells malignant boil furuncle; Snake dog bite.

Ying Azulene: sour, sweet, puckery is flat.Return liver; Stomach warp.Clearing heat and detoxicating, dispel rheumatism.For hepatitis, appendicitis, mastitis, lung abscess, multiple abscess, rheumatic arthritis; Sore swollen toxin is controlled in external application, tympanitis, snake bite and insect sting.

Ji Ni: taste is sweet; Cold in nature.Return lung; The spleen channel.Moistening dryness and resolving phlegm; Clearing heat and detoxicating.Main xeropulmonary cough; Abscess of throat; Quench one's thirst; Malignant boil carbuncle sore; Drug poisoning.

Indian melothria root: bitter, cold in nature.Return lung, liver, spleen three warp.Clearing heat and eliminating phlegm, dampness removing, mass dissipating and swelling eliminating.Control heat to cough, dysentery, gonorrhoea, urinary tract infections, wine subcutaneous ulcer, arthralgia due to wind-dampness, laryngalgia, hot eyes, eczema, carbuncle swells.

Bastardtoadflaxlike swallowwort herb and fruit: sweet is flat.Tonifying lung gas, heat-clearing and fire-reducing, promotes the production of body fluid to quench thirst, anti-inflammatory analgetic.

Snakegourd: taste is sweet; Micro-hardship; Cold in nature.Return lung; Stomach; Large intestine channel.Clearing heat and eliminating phlegm; Wide born of the same parents' dissipating bind; Moisturize laxation.Main cough with lung heat; The obstruction of qi in the chest; Quench one's thirst; Constipation; Carbuncle sore tumefacting virus.

Tuberous sword fern tuber: the sweet band of taste is puckery, property is put down, nontoxic.Promote the production of body fluid to quench thirst, clearing liver, hemostasis.Control diarrhea of having loose bowels, tongue is done thirsty, screen on eyeball, and fall and beat internal injury, knife wound is hemorrhage.

Giant clam meat: taste is sweet; Salty; Cold in nature.Yin-nourishing and body fluid promoting; Clearing heat and detoxicating.Main void is hot in winning; Quench one's thirst; Impotence numbness; Let out dysentery; Pyogenic infections.

Bi Collettii: bitter; Flat.Return liver; Stomach; Urinary bladder channel.Wines used as antirheumatic; Dampness removing is turbid.Main cream drenches; Gonorrhoea; Under band; Sore; Eczema; Arthralgia due to wind-dampness.

Below adopt embodiment to describe embodiments of the present invention in detail, to the present invention, how application technology means solve technical problem whereby, and the implementation procedure reaching technique effect can fully understand and implement according to this.

Embodiment 1 Chinese medicine additive

Get gypsum rubrum 33 weight portion, cape jasmine 11 weight portion, the dried rhizome of rehmannia 24 weight portion, cacumen biotae 36 weight portion, moutan bark 19 weight portion, reed rhizome 21 weight portion, root of Chinese trichosanthes 12 weight portion, lophatherum gracile 35 weight portion, dayflower 29 weight portion, phoenix-tail fern 38 weight portion, pivot stores 14 weight portions, dandelion 25 weight portion, lotus leaf 32 weight portion, lotus nut 17 weight portion, the tuber of dwarf lilyturf 15 weight portion, the capsule of weeping forsythia 16 weight portion, radix scrophulariae 39 weight portion, Radix Glycyrrhizae 32 weight portion, Chinese eriosema root 11 weight portion, Dicliptera chinensis 30 weight portion, Ying Azulene 40 weight portion, Ji Ni 5 weight portion, indian melothria root 17 weight portion, bastardtoadflaxlike swallowwort herb and fruit 24 weight portion, snakegourd 8 weight portion, tuberous sword fern tuber 17 weight portion, giant clam meat 35 weight portion is with Bi Collettii 16 weight portion.

Preparation method comprises the following steps:

The first step, mixes in proportion by described each raw medicinal material, and adding relative to the determining alcohol of mixture quality 3 times is the ethanol of 95%, adds hot reflux 2 hours, extracts, and filters acquisition first extract; Filter the dregs of a decoction obtained to add relative to the determining alcohol of described dregs of a decoction quality 2 times to be again the ethanol of 95%, to add hot reflux 2 hours that acquisition second extract is filtered in extraction; First extract and the second extract are merged, reduced pressure concentration removing alcohol solvent, dry, obtain and get dry extract;

Second step, is placed on the dry cream that the first step obtains in micronizer and pulverizes 2 hours, pulverize, sieve, obtain 400 object micropowders, obtain Chinese medicine additive powder.

Embodiment 2 feed

Embodiments provide a kind of feed for preventing and treating chronic type swine fever epidemic disease, in feed, the parts by weight of each raw material are: wheat bran 65 weight portion, corn 45 weight portion, wheat 28 weight portion, millet 25 weight portion, lotus root starch 19 weight portion, sea-tangle 20 weight portion, asparagus 13 weight portion, grapefruit 15 weight portion, waxgourd peel 17 weight portion, three-coloured amaranth 14 weight portion, dregs of beans 21 weight portion, tomato 30 weight portion, sponge gourd 8 weight portion, lotus seeds 7 weight portion, flat mushroom 6 weight portion, vitamin premix 0.5 weight portion, microelement pre-mix material 0.5 weight portion and Chinese medicine additive 2 weight portion, wherein in Chinese medicine additive, the ratio of weight and number of each raw medicinal material is: gypsum rubrum 33 weight portion, cape jasmine 11 weight portion, the dried rhizome of rehmannia 24 weight portion, cacumen biotae 36 weight portion, moutan bark 19 weight portion, reed rhizome 21 weight portion, root of Chinese trichosanthes 12 weight portion, lophatherum gracile 35 weight portion, dayflower 29 weight portion, phoenix-tail fern 38 weight portion, pivot stores 14 weight portions, dandelion 25 weight portion, lotus leaf 32 weight portion, lotus nut 17 weight portion, the tuber of dwarf lilyturf 15 weight portion, the capsule of weeping forsythia 16 weight portion, radix scrophulariae 39 weight portion, Radix Glycyrrhizae 32 weight portion, Chinese eriosema root 11 weight portion, Dicliptera chinensis 30 weight portion, Ying Azulene 40 weight portion, Ji Ni 5 weight portion, indian melothria root 17 weight portion, bastardtoadflaxlike swallowwort herb and fruit 24 weight portion, snakegourd 8 weight portion, tuberous sword fern tuber 17 weight portion, giant clam meat 35 weight portion is with Bi Collettii 16 weight portion.

Its preparation method comprises the following steps:

(1) take all Chinese medicine additive mixed grindings according to ratio of weight and number and become 250 order fine powders, be prepared into Chinese medicine additive;

(2) get wheat bran, corn, wheat, lotus root starch, millet, sea-tangle, asparagus, grapefruit, waxgourd peel, three-coloured amaranth, dregs of beans, tomato, sponge gourd, lotus seeds, flat mushroom, vitamin premix and microelement pre-mix material in proportion to pulverize, grinding particle size is 300mm, and its fine powder amount is reached, and feedstuff always expects more than 97%;

(3) feedstuff after described step (3) being pulverized is poured in spraying machine, and in spray, water temperature is 70-88 DEG C, opens spraying machine, and stirring minute, continues to be warming up to 98 DEG C and complete expanded;

(4) the expanded product that obtains of pulverising step (3), then the Chinese medicine additive adding that step (1) obtains, obtain mixture, add the water of the parts by weight 10 parts relative to the mixture of 100 weight portions, put into granulator and granulate;

(6) dry after granulating, baking temperature is 110 DEG C, drying time 40min; Then cool, pack.

The toxicity test of Chinese medicine additive:

1, trial drug

Choose gypsum rubrum 33g, cape jasmine 11g, dried rhizome of rehmannia 24g, cacumen biotae 36g, moutan bark 19g, reed rhizome 21g, root of Chinese trichosanthes 12g, lophatherum gracile 35g, dayflower 29g, phoenix-tail fern 38g, pivot store 14g, dandelion 25g, lotus leaf 32g, lotus nut 17g, the tuber of dwarf lilyturf 15g, capsule of weeping forsythia 16g, radix scrophulariae 39g, Radix Glycyrrhizae 32g, Chinese eriosema root 11g, Dicliptera chinensis 30g, Ying Azulene 40g, Ji Ni 5g, indian melothria root 17g, bastardtoadflaxlike swallowwort herb and fruit 24g, snakegourd 8g, tuberous sword fern tuber 17g, giant clam meat 35g with Bi Collettii 16g mixes, be ground into powder; Added by acquisition powder in 1400g cold water and soak 25 hours, with slow fire boiling, decocting time is 1.5 hours, decoction liquor is filtered, obtains the first filtrate, collects filter residue; Again add in 1400g cold water by filtering the filter residue obtained, with slow fire boiling 3 times, each decoction 1 hour, filters and merges filtered fluid, obtaining the second filtrate; Merge twice filtrate, reduced pressure concentration remove portion water, obtain decoction, the crude drug concentration of decoction is 3g/ml.

2, test method: select SD rat, give the decoction of the Chinese medicine additive of the present invention of variable concentrations (18.0,6.0,2.0g crude drug/kg), every day gavage once, continuous 90 days, within after last administration 24 hours, respectively group is alive kills 1/2 animal (male and female half and half), and all the other 1/2 animals continue observations 2 weeks rear living and kill.Duration of test observes outward appearance, general behavior, food ration, the changes of weight of animal, within after administration 90 days, within 2 weeks, carries out the index checking such as hematology (RBC, HB, granulophilocyte, PLT, CT, WBC and classification) and blood biochemical (AST, ALT, ALP, Glu, BUN, Crca, TP, T.BIL, ALB, CHOL), urine biochemistry, organ coefficient, Histopathology with drug withdrawal.Result of the test shows: Chinese medicine additive of the present invention is good at high, medium and low dosage treated animal general state, and outward appearance sign, behavioral activity, food-intake and body weight increase change all without exception; Three dosage groups and control group hematological examination, blood biochemical analysis, urine biochemical analysis all in normal range (NR), without significant difference between group; Each group of main organs histopathological examination shows no obvious abnormalities.These parameters drug withdrawal also had no change after 2 weeks.This test dosage is respectively 180,60,20 times of clinical medicine dose, rat is had no significant effect in high, medium and low three dosage (18.0,6.0,2.0g crude drug/kg) administration in continuous 90 days according to result of the test Chinese medicine preparation of the present invention, without clear and definite toxicity target organ and sensitive indicator, convalescence observation also has no retardance toxic reaction, points out the dose safety of Chinese medicine preparation clinical practice of the present invention higher.

Contrast test

Pig farm, Hebei Handan City, since in April, 2010, in the piglet group of wean (40 ~ 60 age in days), the death rate that lasting appearance is higher.Low during height when the cardinal symptom of sick pig is body temperature, diarrhoea (ight soil is yellowish), becomes thin, poor appetite, and secret and diarrhoea is normal alternately to be occurred, sick pig skeletonize, anaemia, hind limb weakness during walking.There is bluish violet or necrosis in some sick pig have sharp ears and four limbs.Cut open inspection in the pathology of septicemia, enteron aisle has hyperemia in various degree, hemorrhage, at large intestine and ileal valve position, obvious ulcer occurs.Enlargement of lymph nodes, hyperemia, hemorrhage and oedema.Once in the body of some sick pigs, be separated to the bacteriums such as Escherichia coli, salmonella and streptococcus, but use multiple antibacterials and take corresponding prophylactico-therapeutic measures, produced little effect.Analyse and be diagnosed as chronic type swine fever.

Choose the ill piglet 100 that 45 ages in days are made a definite diagnosis, 100 ill piglets are divided into two groups at random, are respectively embodiment group and control group, the ill piglet of two groups all without significant difference, has comparativity in body weight, the state of an illness etc.Embodiment group and control group use the feed of the embodiment of the present invention 2 and conventional feed to feed ill piglet respectively, feed continuously 7 days, wherein; Control group also needs to carry out conventional therapy and hypodermic injection hyper-immune serum 0.4 milliliter/KG, once-a-day, and Radix Astragali polysaccharide injection intramuscular injection 3ml/ time, 2 times on the one; Simultaneously in feed, add terramycin according to 2:1000 to mix conventional feed and feed, conventional feed of feeding.Experimental period is 7 days, takes each group of ill pig weight respectively before and after experiment, and period records recovery from illness situation and the death toll of ill piglet, and calculate average daily gain and cure rate, result as shown in Table 1 and Table 2.Wherein, cure: spirit is normal, drinking-water of searching for food is normal, and ight soil is normal, bouncing, and it is normal that the histoorgans such as inspection liver, enteron aisle, the bursa of farbricius, pancreas are cutd open in sampling; Invalid: clinical symptoms are not improved and even increased the weight of or death.

The table 1 liang experimental group piglet average weight table of comparisons

Data from table 1: compared with control group, use the piglet that feed of the present invention is fed, and during to piglet 52 age in days, the piglet that its average weight is treated than traditional therapy exceeds 1.9kg, and average daily gain exceeds 0.26kg/d.

The result for the treatment of table of comparisons of table 2 liang experimental group piglet

Data from table 2: compared with conventional medicament, the feed of the embodiment of the present invention 2 has advantage that is evident in efficacy, cheap, that have no side effect in treatment chronic type swine fever.

Known by contrast test: ill piglet average weight, the cure rate of the mixed feed nursing of the embodiment of the present invention 2 are all better than control group, namely feed of the present invention can not only treat swine fever, the nutritional need of piglet can also be met, be specially adapted to the nutritional need of the piglet suffering from chronic type swine fever.

Model case

The piglet of 150 40-55 ages in days of Hebei in January, 2013 Handan self-employed pig raiser raising, nearly becoming thin appears in 27 piglets, anaemia, and asthenia universalis, often lies prostrate, and gait is slowly unable, poor appetite, and constipation and diarrhoea are alternately.Cut open inspection pig and show as splanchnocoel ponding, the external membrane of heart is hemorrhage, and liver turns yellow, and there is volume blutpunkte on surface, spleen edge infarct, and lymph nodes of body as a whole oedema, hyperemia, periphery are hemorrhage.Kidney is khaki, and there is the blutpunkte of needle point size on surface, and medullary substance, renal plevis portion are hemorrhage, and mucous membrane of urinary bladder has the blutpunkte of being dispersed in property.Mesenterium oedema, colorectal mucosa is hemorrhage, hemorrhage of tonsil, and larynx myxedema has hemorrhage spot.Pick up from spleen and the lymph node of the routine sick pig in pig farm 5, get pathological material of disease suspension point sample on nitrocellulose filter, natural drying; Use 10% skim milk, close 30 minutes for 37 DEG C; With PBS rinsing 3 times; The anti-hog cholera antibody IgG of enzyme-added mark, 37 DEG C are reacted 2 hours; The same rinsing; Add DAB colour developing lucifuge and react 15 minutes; Tap water rinse, cessation reaction; Occur that rufous spot is judged to the positive.

Be diagnosed as chronic type swine fever.Place is raised immediately by not occurring that the piglet of symptom isolates.Choose 14 ill piglets wherein, the feed of the embodiment of the present invention 2 that starts to feed, feed 7 days, within the 3rd day, ill piglet symptom is obviously improved, and within the 5th day, 13 piglets are all fully recovered, and after continuing to feed 4 days, compared with sodium selenite, average weight is substantially identical.

The foregoing is only preferred embodiment of the present invention, not in order to limit the present invention, within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.

Claims (9)

1. for preventing and treating the functional collaboration feed of chronic type swine fever epidemic disease, it is characterized in that, described feed comprises following raw material: wheat bran, corn, wheat, lotus root starch, millet, sea-tangle, asparagus, grapefruit, waxgourd peel, three-coloured amaranth, dregs of beans, tomato, sponge gourd, lotus seeds, flat mushroom, vitamin premix and microelement pre-mix material.

2. the functional collaboration feed for preventing and treating chronic type swine fever epidemic disease according to claim 1, it is characterized in that, in described feed, the parts by weight of each raw material are: wheat bran 40-65 weight portion, corn 25-45 weight portion, wheat 20-32 weight portion, millet 20-28 weight portion, lotus root starch 15-30 weight portion, sea-tangle 15-25 weight portion, asparagus 7-14 weight portion, grapefruit 8-17 weight portion, waxgourd peel 15-20 weight portion, three-coloured amaranth 10-19 weight portion, dregs of beans 10-22 weight portion, tomato 15-35 weight portion, sponge gourd 7-16 weight portion, lotus seeds 5-10 weight portion, flat mushroom 4-9 weight portion, vitamin premix 0.3-0.5 weight portion and microelement pre-mix material 0.3-0.5 weight portion.

3. the functional collaboration feed for preventing and treating chronic type swine fever epidemic disease according to claim 1 and 2, it is characterized in that, described feed also comprises Chinese medicine additive, in described feed, the parts by weight of each raw material are: wheat bran 40-65 weight portion, corn 25-45 weight portion, wheat 20-32 weight portion, millet 20-28 weight portion, lotus root starch 15-30 weight portion, sea-tangle 15-25 weight portion, asparagus 7-14 weight portion, grapefruit 8-17 weight portion, waxgourd peel 15-20 weight portion, three-coloured amaranth 10-19 weight portion, dregs of beans 10-22 weight portion, tomato 15-35 weight portion, sponge gourd 7-16 weight portion, lotus seeds 5-10 weight portion, flat mushroom 4-9 weight portion, vitamin premix 0.3-0.5 weight portion, microelement pre-mix material 0.3-0.5 weight portion and Chinese medicine additive 2-4 weight portion.

4. the functional collaboration feed for preventing and treating chronic type swine fever epidemic disease according to any one of claim 1-3, it is characterized in that, in described feed, the parts by weight of each raw material are: wheat bran 65 weight portion, corn 45 weight portion, wheat 28 weight portion, millet 25 weight portion, lotus root starch 19 weight portion, sea-tangle 20 weight portion, asparagus 13 weight portion, grapefruit 15 weight portion, waxgourd peel 17 weight portion, three-coloured amaranth 14 weight portion, dregs of beans 21 weight portion, tomato 30 weight portion, sponge gourd 8 weight portion, lotus seeds 7 weight portion, flat mushroom 6 weight portion, vitamin premix 0.5 weight portion, microelement pre-mix material 0.5 weight portion and Chinese medicine additive 2 weight portion.

5. the functional collaboration feed for preventing and treating chronic type swine fever epidemic disease according to any one of claim 1-4, it is characterized in that, described Chinese medicine additive comprises following raw medicinal material: gypsum rubrum, cape jasmine, the dried rhizome of rehmannia, cacumen biotae, moutan bark, reed rhizome, root of Chinese trichosanthes, lophatherum gracile, dayflower, phoenix-tail fern, pivot store, dandelion, lotus leaf, lotus nut, the tuber of dwarf lilyturf, the capsule of weeping forsythia, radix scrophulariae, Radix Glycyrrhizae, Chinese eriosema root, Dicliptera chinensis, Ying Azulene, Ji Ni, indian melothria root, bastardtoadflaxlike swallowwort herb and fruit, snakegourd, tuberous sword fern tuber, giant clam meat is with Bi Collettii.

6. the functional collaboration feed for preventing and treating chronic type swine fever epidemic disease according to any one of claim 1-5, it is characterized in that, in described Chinese medicine additive, the parts by weight of each raw medicinal material are: gypsum rubrum 23-36 part, cape jasmine 7-15 part, dried rhizome of rehmannia 17-35 part, cacumen biotae 25-40 part, moutan bark 9-25 part, reed rhizome 13-27 part, root of Chinese trichosanthes 10-28 part, lophatherum gracile 25-38 part, dayflower 28-40 part, phoenix-tail fern 26-39 part, pivot stores 12-32 part, dandelion 12-37 part, lotus leaf 20-35 part, lotus nut 15-28 part, the tuber of dwarf lilyturf 15-30 part, capsule of weeping forsythia 12-25 part, radix scrophulariae 25-40 part, Radix Glycyrrhizae 15-32 part, Chinese eriosema root 11-23 part, Dicliptera chinensis 17-30 part, Ying Azulene 26-42 part, Ji Ni 3-10 part, indian melothria root 15-29 part, bastardtoadflaxlike swallowwort herb and fruit 20-37 part, snakegourd 7-23 part, tuberous sword fern tuber 11-29 part, giant clam meat 20-38 part is with Bi Collettii 14-29 part.

7. the functional collaboration feed for preventing and treating chronic type swine fever epidemic disease according to any one of claim 1-6, it is characterized in that, in described Chinese medicine additive, the parts by weight of each raw medicinal material are: gypsum rubrum 33 parts, cape jasmine 11 parts, 24 parts, the dried rhizome of rehmannia, cacumen biotae 36 parts, moutan bark 19 parts, reed rhizome 21 parts, root of Chinese trichosanthes 12 parts, lophatherum gracile 35 parts, dayflower 29 parts, phoenix-tail fern 38 parts, pivot stores 14 parts, dandelion 25 parts, 32 parts, lotus leaf, lotus nut 17 parts, the tuber of dwarf lilyturf 15 parts, the capsule of weeping forsythia 16 parts, radix scrophulariae 39 parts, 32 parts, Radix Glycyrrhizae, Chinese eriosema root 11 parts, Dicliptera chinensis 30 parts, Ying Azulene 40 parts, Ji Ni 5 parts, indian melothria root 17 parts, bastardtoadflaxlike swallowwort herb and fruit 24 parts, snakegourd 8 parts, tuberous sword fern tuber 17 parts, giant clam meat 35 parts of He Bi Collettii 16 parts.

8. the functional collaboration feed for preventing and treating chronic type swine fever epidemic disease according to any one of claim 1-7, it is characterized in that, the preparation method of described Chinese medicine additive comprises the following steps:

The first step, mixes in proportion by described each raw medicinal material, and adding relative to the determining alcohol of mixture quality 2 ~ 4 times is the ethanol of 85 ~ 95%, adds hot reflux 1 ~ 3 hour, extracts, and filters acquisition first extract; Filter the dregs of a decoction obtained to add relative to the determining alcohol of described dregs of a decoction quality 1 ~ 2 times to be again the ethanol of 85 ~ 95%, to add hot reflux 1 ~ 3 hour that acquisition second extract is filtered in extraction; First extract and the second extract are merged, reduced pressure concentration removing alcohol solvent, dry, obtain and get dry extract;

Second step, is placed on the dry cream that the first step obtains in micronizer and pulverizes 1 ~ 2 hour, pulverize, sieve, obtain 300 order ~ 400 object micropowders, obtain Chinese medicine additive powder.

9. the preparation method of the functional collaboration feed for preventing and treating chronic type swine fever epidemic disease according to any one of claim 1-8, it is characterized in that, described preparation method comprises the following steps:

(1) take all Chinese medicine additive mixed grindings according to ratio of weight and number and become 180-250 order fine powder, be prepared into Chinese medicine additive;

(2) get wheat bran, corn, wheat, lotus root starch, millet, sea-tangle, asparagus, grapefruit, waxgourd peel, three-coloured amaranth, dregs of beans, tomato, sponge gourd, lotus seeds, flat mushroom, vitamin premix and microelement pre-mix material in proportion to pulverize, grinding particle size is 300-500mm, and its fine powder amount is reached, and feedstuff always expects more than 97%;

(3) feedstuff after described step (3) being pulverized is poured in spraying machine, and in spray, water temperature is 70-88 DEG C, opens spraying machine, stirs 10-15 minute, continues to be warming up to 98 DEG C and complete expanded;

(4) the expanded product that obtains of pulverising step (3), then the Chinese medicine additive adding that step (1) obtains, obtain mixture, add the water of parts by weight 7-15 part of the mixture relative to 100 weight portions, put into granulator and granulate;

(6) dry after granulating, baking temperature is 105 DEG C ~ 112 DEG C, drying time 30-50min; Then cool, pack.