CN104256165B - For preventing and treating functional feed of chronic type swine fever epidemic disease and preparation method thereof - Google Patents

Abstract

The invention discloses a kind of functional collaboration feedstuff for preventing and treating chronic type swine fever epidemic disease and preparation method thereof, wherein feedstuff includes following raw material: Testa Tritici, Semen Maydis, Semen Tritici aestivi, Amylum Nelumbinis Rhizomatis, Semen setariae, Thallus Laminariae (Thallus Eckloniae), Germinatus Phragmitis, Citrua paradiai, Exocarpium Benincasae, Amaranthus mangostanus L., bean cake, Fructus Lycopersici esculenti, Fructus Luffae, Semen Nelumbinis, Pleurotus ostreatus, vitamin premix and microelement pre-mix material.The invention has the beneficial effects as follows: the feedstuff of the present invention contain there is heat-clearing and toxic substances removing, the Chinese medicine additive of effect that removing heat from blood promotes the production of body fluid, can strengthening vital QI to eliminate pathogenic factors, there is the course for the treatment of shorter, curative effect is preferable, drug residue free, the advantages such as cost price is cheap, make pig yang blood and qi be in harmonious proportion, treatment short treating period, effect is preferable, residual quantity low while can strengthen the immunity of pig and see resistance against diseases, green non-pollution.

Description

For preventing and treating functional feed of chronic type swine fever epidemic disease and preparation method thereof

Technical field

The present invention relates to bird feed, particularly to a kind of functional collaboration feedstuff for preventing and treating chronic type swine fever epidemic disease and Its preparation method.

Background technology

Swine fever is a kind of hyperinfection and lethal epidemic disease caused by swine fever virus, it is characterized by that high heat is delaied with little The most hemorrhage, infraction that vascular degeneration causes and downright bad.The pig premunition of infected pigs's Pestivirus reduces, easily concurrent or secondary pig Lung plague.Especially cold, moist, cold and heat succeed each other, weather drastic change, under the bad condition such as crowded, improper ventilation, make pig body resist Power reduces, and can cause pasteurellosis bacillus amount reproduction, and virulence strengthens and falls ill, and as controlled not in time, can cause the large quantities of death of pig.

Clinical symptoms disease pig spirit is depressed, and body temperature is increased to 40 DEG C～41.5 DEG C.In continued fever, loss of appetite is the most useless Absolutely, the dense sexual secretion of eye stream.Visual mucosa cyanosis.Sick just constipation, after have loose bowels, stench band blood is also mixed with white mucosa.Whole body is sent out Red, have sharp ears, abdominal part, cervical region and limbs skin have purpura, finger pressure not to fade.Boar foreskin has muddy urine, and neck swelling is hard, The sensitivity touched.Sick pig cough, dyspnea, to call hoarse, nose flows out serosity or sticky secretions, indivedual hog snout holes elution band Bleeding blister foam, serious in dog sitting posture mouth breathing, eventually because of death by suffocation.Inspection sick dead pig is cutd open in pathological change altogether, and pathological change is basic Similar, lymph nodes of body as a whole enlargement, hemorrhage, in kermesinus；Stomach bottom mucosa, bladder mucosa are hemorrhage；Spleen surface has mound shape point The hemorrhage hemorrhage infarction with Semen phaseoli radiati size mulberry, there is needle point massive hemorrhage point on surface；Ileocecal valve, caecum and colonic mucosa have button Shape ulcer；Larynx has ecchymosis and petechia；Heart hat fat, endocardium have petechia；Pulmonary edema is furvous, and has and be dispersed in Pneumonia stove not of uniform size；There is mucus blister secretions in trachea-bronchial epithelial cell, and be mixed with quantity courageous and upright foam not etc.；Thoracic cavity Long-pending with pericardium have the pink turbid liquid of volume；Cervical region subcutaneous dropsy, flush, congestion.

Pestilence is the most on the books in China's historical data.As " week gift heavenly officials tomb kill " is recorded: " physician slaps the disease of foster ten thousand people Disease, all has pestilence disease when four." " Springs and Autumns of Master Lü last month of spring discipline " record: " summer weather in spring in season, the then people's many diseases epidemic disease." illustrate at that time to pestilence The understanding of epidemic disease has reached certain level, it is believed that pestilence the most all can occur, and one of reason is due to the gas in season Abnormal, " gas time non-" cause.The Chinese medical book Huangdi's Internal Classics of earliest extant is the most on the books.As " Plain Questions is stung Method opinion " point out: " five types of pestilence extremely, all to dye easily, without asking size, condition of illness is similar ..., in healthy energy is deposited, heresy can not be done, and keeps away its poison Gas." " Plain Questions instinct sick " piece: " and the moon of fainting is not given up the throne, i.e. strong wind is early lifted, time rain do not drop, wet order is not changed, people's suffering from epidemic febrile disease epidemic disease, and defect gives up. Humorously, people's disease all arthrodynia of the extremities, head's pain, latent heat restlessness, the dry taking fluids profusely of throat." point out that pestilence has infectiousness, popularity, clinic Show similar, the morbidity feature such as relevant with weather, as long as and thinking " in healthy energy is deposited ", with regard to energy " preventing the invasion of infectious pathogen ".

Using Western medicine to prevent and treat this disease and mostly use antibiotic, the bacterial strain developing immunity to drugs these medicines has occurred and has had Increase trend, additionally, these chemicalses substantially can cause pig drug disposition to remain, and then affect human and livestock health and even endanger Public health.Western medical treatment swine fever epidemic disease course for the treatment of is longer, the undesirable epidemic situation of effect is wayward, can cause the biggest economic loss.

But China's Chinese medicine and pharmacy just had understanding before 2 over thousands of years to pestilence (infectious disease), and propose the most anti- Model and treatment, as the Zhou Dynasty " Book of Rites. month " record " the row autumn first month of spring then people sick big epidemic disease ", Huangdi's Internal Classics has " five types of pestilence extremely All pass on from one to another to without asking that size condition of illness is similar " clearly propose infectiousness and the epidemic characteristic of epidemic disease, the additionally side of Herba Artemisiae Annuae treating malaria disease Method is generally recognised as the medicine dedicated of malaria in the world so far in the world, and in conjunction with in current " swine flu " preventing and treating, health ministry clearly carries Go out Chinese medicine participation control prece and more demonstrate China's Chinese Traditional Medicine status in preventing and treating pestilence and effect.

It is generally 5-7 d the incubation period of natural infection swine fever, short for 2 d, long up to 21 d.According to the state of an illness and disease Journey, is often divided into acute, acute, chronic type and delayed in clinical symptoms by swine fever.

1, acute is more common in popular initial stage, sudden onset, and symptom drastically, shows general spasticity, tic of the limbs, high heat Delay, skin and mucosa cyanosis, have hemorrhage speckle, dead through 18 days.2, acute.This kind of is most commonly seen.Sick pig is occurring Before symptom, body temperature has raised at 41 degrees centigrade the most, persistent, show as slow in action, the most sagging, hogback, shiver, Thirsty, often drowsiness at sleeping one, eye conjunctiva inflammation, the puffiness of the eyes, secretions increase, at hypogastric region, the basal part of the ear, four hoof, lip, pudendum Etc. visible aubergine speckle.Sick difficulty of just discharging feces, occurs diarrhoea soon, and feces is lark.Boar foreskin inner product has urine Liquid, flows out muddy canescence stench liquid with hands after extruding.Suckling pig also can occur acute swine fever, mainly shows neurosis Shape, as ground one's teeth in sleep, spasm, opisthotonus or the tic that falls down to the ground, finally dead.3, chronic type.Main performance is become thin, and anemia, whole body declines Weak, often to lie prostrate, gait is the most unable, inappetence, and constipation and diarrhoea are alternately.The sick pig having is at ear end, tail point and limbs skin On have purpura or downright bad crust.The course of disease more than one month.Died long term development is not bad becomes cad pig.After in-pig infects, Virus may be passed to fetus by Placenta Hominis, cause miscarriage, after producing stillborn fetus or the small and weak piglet of output or wean, diarrhoea occur.4、 Mild.PD is slow, and sick temperature of pig body is typically at 40 41 degrees Celsius, and skin is often without hemorrhage point, but many at hypogastrium See blood stasis and necrosis.The most visible ear and tail skin are downright bad, and paddy claims dry ear, dry tail.The course of disease was up to 2-3 month.

Summary of the invention

The technical problem to be solved is to be to provide a kind of Chinese medicine for preventing and treating chronic type swine fever epidemic disease to add The functional feed of agent, uses and overcomes the various of Chinese medicine of the prior art and Western medicine containing the Feed Energy of this Chinese medicine additive Defect, has heat-clearing and toxic substances removing to the treatment of the pig suffering from swine fever epidemic disease, removing heat from blood promotes the production of body fluid, and makes pig yang blood and qi be in harmonious proportion, treatment short treating period, Effect is preferable, residual quantity low while can strengthen the immunity of pig and see resistance against diseases, green non-pollution.

In order to realize foregoing invention purpose, the invention provides a kind of functional collaboration for preventing and treating chronic type swine fever epidemic disease Feedstuff, described feedstuff includes following raw material: Testa Tritici, Semen Maydis, Semen Tritici aestivi, Amylum Nelumbinis Rhizomatis, Semen setariae, Thallus Laminariae (Thallus Eckloniae), Germinatus Phragmitis, Citrua paradiai, Exocarpium Benincasae, Herba Amaranthi tricoloris Dish, bean cake, Fructus Lycopersici esculenti, Fructus Luffae, Semen Nelumbinis, Pleurotus ostreatus, vitamin premix and microelement pre-mix material.

In described feedstuff, the parts by weight of each raw material are: Testa Tritici 40-65 weight portion, Semen Maydis 25-45 weight portion, Semen Tritici aestivi 20- 32 weight portions, Semen setariae 20-28 weight portion, Amylum Nelumbinis Rhizomatis 15-30 weight portion, Thallus Laminariae (Thallus Eckloniae) 15-25 weight portion, Germinatus Phragmitis 7-14 weight portion, Citrua paradiai 8-17 weight portion, Exocarpium Benincasae 15-20 weight portion, Amaranthus mangostanus L. 10-19 weight portion, bean cake 10-22 weight portion, Fructus Lycopersici esculenti 15-35 weight portion, Fructus Luffae 7-16 weight portion, Semen Nelumbinis 5-10 weight portion, Pleurotus ostreatus 4-9 weight portion, vitamin premix 0.3-0.5 weight portion and trace unit Element premix material 0.3-0.5 weight portion.

Described feedstuff also includes Chinese medicine additive, and in described feedstuff, the parts by weight of each raw material are: Testa Tritici 40-65 weight Part, Semen Maydis 25-45 weight portion, Semen Tritici aestivi 20-32 weight portion, Semen setariae 20-28 weight portion, Amylum Nelumbinis Rhizomatis 15-30 weight portion, Thallus Laminariae (Thallus Eckloniae) 15-25 Weight portion, Germinatus Phragmitis 7-14 weight portion, Citrua paradiai 8-17 weight portion, Exocarpium Benincasae 15-20 weight portion, Amaranthus mangostanus L. 10-19 weight portion, bean cake 10-22 weight portion, Fructus Lycopersici esculenti 15-35 weight portion, Fructus Luffae 7-16 weight portion, Semen Nelumbinis 5-10 weight portion, Pleurotus ostreatus 4-9 weight portion, dimension are raw Element premix material 0.3-0.5 weight portion, microelement pre-mix material 0.3-0.5 weight portion and Chinese medicine additive 2-4 weight portion.

In described feedstuff, the parts by weight of each raw material are: Testa Tritici 65 weight portion, Semen Maydis 45 weight portion, Semen Tritici aestivi 28 weight Part, Semen setariae 25 weight portion, Amylum Nelumbinis Rhizomatis 19 weight portion, Thallus Laminariae (Thallus Eckloniae) 20 weight portion, Germinatus Phragmitis 13 weight portion, Citrua paradiai 15 weight portion, Exocarpium Benincasae 17 Weight portion, Amaranthus mangostanus L. 14 weight portion, bean cake 21 weight portion, Fructus Lycopersici esculenti 30 weight portion, Fructus Luffae 8 weight portion, Semen Nelumbinis 7 weight portion, Pleurotus ostreatus 6 weight Amount part, vitamin premix 0.5 weight portion, microelement pre-mix material 0.5 weight portion and Chinese medicine additive 2 weight portion.

Described Chinese medicine additive includes following raw medicinal material: Mirabilitum crystallina, Fructus Gardeniae, the Radix Rehmanniae, Cacumen Platycladi, Cortex Moutan, Rhizoma Phragmitis, sky Pollen, Herba Lophatheri, Herba Commelinae, Herba Pteridis Multifidae, storage, Herba Taraxaci, Folium Nelumbinis, Plumula Nelumbinis, Radix Ophiopogonis, Fructus Forsythiae, Radix Scrophulariae, Radix Glycyrrhizae, Radix eriosematis chinensis, Herba Diclipterae Chinensis, shepherd's purse, Radix Melothriae Heterophyllae, Herba Cynanchi Thesioidis, Fructus Trichosanthis, Rhizoma Nephrolepis cordifoliae, Concha Tridacna squamosa meat and Bi.

In described Chinese medicine additive, the parts by weight of each raw medicinal material are: Mirabilitum crystallina 23-36 part, Fructus Gardeniae 7-15 part, the Radix Rehmanniae 17-35 part, Cacumen Platycladi 25-40 part, Cortex Moutan 9-25 part, Rhizoma Phragmitis 13-27 part, Radix Trichosanthis 10-28 part, Herba Lophatheri 25-38 part, duck Sole of the foot grass 28-40 part, Herba Pteridis Multifidae 26-39 part, storage 12-32 part, Herba Taraxaci 12-37 part, Folium Nelumbinis 20-35 part, Plumula Nelumbinis 15-28 Part, 15-30 part Radix Ophiopogonis, Fructus Forsythiae 12-25 part, Radix Scrophulariae 25-40 part, Radix Glycyrrhizae 15-32 part, Radix eriosematis chinensis 11-23 part, Herba Diclipterae Chinensis 17-30 Part, 26-42 part, shepherd's purse 3-10 part, Radix Melothriae Heterophyllae 15-29 part, Herba Cynanchi Thesioidis 20-37 part, Fructus Trichosanthis 7-23 part, Rhizoma Nephrolepis cordifoliae 11-29 Part, Concha Tridacna squamosa meat 20-38 part and Bi 14-29 part.

In described Chinese medicine additive, the parts by weight of each raw medicinal material are: Mirabilitum crystallina 33 parts, Fructus Gardeniae 11 parts, 24 parts of the Radix Rehmanniae, Cacumen Platycladi 36 parts, Cortex Moutan 19 parts, Rhizoma Phragmitis 21 parts, Radix Trichosanthis 12 parts, Herba Lophatheri 35 parts, Herba Commelinae 29 parts, Herba Pteridis Multifidae 38 parts, Store 14 parts, Herba Taraxaci 25 parts, 32 parts of Folium Nelumbinis, Plumula Nelumbinis 17 parts, Radix Ophiopogonis 15 parts, Fructus Forsythiae 16 parts, Radix Scrophulariae 39 parts, 32 parts of Radix Glycyrrhizae, pig Young large bamboo hat with a conical crown and broad brim 11 parts, Herba Diclipterae Chinensis 30 parts, 40 parts, shepherd's purse 5 parts, Radix Melothriae Heterophyllae 17 parts, Herba Cynanchi Thesioidis 24 parts, Fructus Trichosanthis 8 parts, Rhizoma Nephrolepis cordifoliae 17 Part, Concha Tridacna squamosa meat 35 parts and Bi 16 parts.

The preparation method of described Chinese medicine additive comprises the following steps:

The first step, is mixed in proportion described each raw medicinal material, adds relative to mixture quality 2～the determining alcohol of 4 times It is the ethanol of 85～95%, is heated to reflux 1～3 hour, extract, filter and obtain the first extracting solution；Filter the medicinal residues obtained to add Relative to described medicinal residues quality 1～the ethanol that determining alcohol is 85～95% of 2 times, being heated to reflux 1～3 hour, extract, filtration obtains Obtain the second extracting solution；First extracting solution and the second extracting solution being merged, concentrating under reduced pressure removes alcohol solvent, is dried, it is thus achieved that dry cream；

Second step, is placed in super micron mill pulverizing 1～2 hour by the dry cream that the first step obtains, and pulverizes, sieves, obtain Obtain 300 mesh～the micropowders of 400 mesh, it is thus achieved that Chinese medicine additive powder.

In order to goal of the invention is better achieved, the present invention also provides for a kind of mixed feed for preventing and treating chronic type swine fever epidemic disease Preparation method, described preparation method comprises the following steps:

(1) weigh all Chinese medicine additive mixed grindings according to ratio of weight and number and become 180-250 mesh fine powder, be prepared as Chinese medicine Additive；

(2) take in proportion Testa Tritici, Semen Maydis, Semen Tritici aestivi, Amylum Nelumbinis Rhizomatis, Semen setariae, Thallus Laminariae (Thallus Eckloniae), Germinatus Phragmitis, Citrua paradiai, Exocarpium Benincasae, Amaranthus mangostanus L., bean cake, Fructus Lycopersici esculenti, Fructus Luffae, Semen Nelumbinis, Pleurotus ostreatus, vitamin premix and microelement pre-mix material are pulverized, and grinding particle size is 300-500mm so that it is Fine powder amount reaches more than 97% that feedstuff is always expected；

(3) feedstuff after described step (3) being pulverized is poured in spraying machine, and in spray, water temperature is 70-88 DEG C, beats Drive spraying machine, stir 10-15 minute, be continuously heating to 98 DEG C and complete expanded；

(4) the expanded product that pulverising step (3) obtains, adds the Chinese medicine additive that step (1) obtains, obtains mixture, Add the water of parts by weight 7-15 part of the mixture relative to 100 weight portions, put in granulator and pelletize；

(6) pelletize after be dried, baking temperature is 105 DEG C～112 DEG C, drying time 30-50min；Then cool down, pack.

The invention has the beneficial effects as follows: the feedstuff of the present invention contain there is heat-clearing and toxic substances removing, the Chinese medicine of effect that removing heat from blood promotes the production of body fluid Additive, can strengthening vital QI to eliminate pathogenic factors, there is the course for the treatment of shorter, curative effect is preferable, drug residue free, the advantages such as cost price is cheap, makes pig cloudy Yang-energy blood is in harmonious proportion, treatment short treating period, effect is preferable, residual quantity low while can strengthen the immunity of pig and see resistance against diseases, green Color is pollution-free.

Detailed description of the invention

Chinese medicine additive refer to China to the physical property of the Nature Chinese herbal medicine (yin, yang, tremble with fear, freeze, temperature, heat), thing taste (acid, Sweet, bitter, peppery, salty) and the traditional theory of material relation is taken as the leading factor and to raise and the subjects theory such as feed industry and technology are for depending on Torr, the single and compound Chinese herbal medicine additive developed or intermixture.From modern pharmacology analysis, effectively become with Chinese herbal medicine Being divided into the feed additive of main body, have immunologic function and the non-specific antimicrobial effect of regulation body, Chinese herbal medicine contains anti- The bioactive substances such as the alkaloid of antibacterial composition, polysaccharide, two class volatile oil, organic acid flavone and bioflavonoids, exchange Joint human body immune function, good effect of improving health conditions.It is reported, ward off more have promotion thymus reaction, stimulate netted Endotheliocyte improves specific antigen respond；Alkaloid can strengthen body fluid and cellular immune function, and stimulates huge biting carefully The phagocytic function of born of the same parents, two classes can strengthen the phagocytic function of reticuloendothelial system, and can promote antibody tormation, promote that antigen-antibody is anti- Should can regulate enteral and prevent the breeding of noxious bacteria and improve the activity of enzyme with lymphocyte transformation organic acid, making animal body Intracellular metabolic can be normally carried out.Folding Chinese medicine feed additive is divided not contain only a number of battalion from the theory of modern nutriology Support material, but also containing a number of unknown growth regulator and pigment, have and activate body directly or indirectly Biochemical reaction, strengthens biosynthesis effect, thus promotes the production performance of animal.

Chinese medicine additive of the present invention is mainly theoretical according to traditional Chinese medical science strengthening vital QI to eliminate pathogenic factors, theory of Chinese medical science think righting and eliminating evil be mutual Two aspects of contact, hold up precisely in order to eliminating evil, by the method strengthening healthy energy, get rid of evils and go out, thus get well, i.e. so-called " just containing evil from dispelling ".Eliminating evil is for righting, eliminates the infringement of paathogenic factor and reaches to protect healthy energy, restorative purpose, I.e. so-called " heresy is gone just from peace ".Righting with eliminating evil be complementary two aspects.When therefore using the rule for the treatment of of strengthening vital QI to eliminate pathogenic factors, Conscientiously carefully analyze the contrast situation of good and evil strength, know the secondary from the primary, determine righting or eliminating evil, or determine the priority of strengthening vital QI to eliminate pathogenic factors. Generally, righting is used for deficiency syndrome；Eliminating evil for excess syndrome；If belonging to deficiency syndrome mingling with excess syndrome card, then answer strengthening vital QI to eliminate pathogenic factors use, but this double Gu is not righting and eliminating evil half and half, is the primary and secondary emergency of deficiency and excess to be distinguished, to determine the primary and secondary, successively of strengthening vital QI to eliminate pathogenic factors.Always It, should be with " righting will not stay heresy, eliminating evil just do not causing injury " for degree.

Chinese medicine additive of the present invention follows the ultimate principle of " strengthening vital QI to eliminate pathogenic factors ", it then follows the principle that heat-clearing and toxic substances removing, removing heat from blood promote the production of body fluid, Providing a kind of feedstuff for preventing and treating chronic type swine fever epidemic disease, it includes that Chinese medicine additive, Chinese medicine additive include following raw material Medical material: Mirabilitum crystallina, Fructus Gardeniae, the Radix Rehmanniae, Cacumen Platycladi, Cortex Moutan, Rhizoma Phragmitis, Radix Trichosanthis, Herba Lophatheri, Herba Commelinae, Herba Pteridis Multifidae, storage, Pu Herba Taraxaci, Folium Nelumbinis, Plumula Nelumbinis, Radix Ophiopogonis, Fructus Forsythiae, Radix Scrophulariae, Radix Glycyrrhizae, Radix eriosematis chinensis, Herba Diclipterae Chinensis, shepherd's purse, Radix Melothriae Heterophyllae, Herba Cynanchi Thesioidis, Chinese juniper Building, Rhizoma Nephrolepis cordifoliae, Concha Tridacna squamosa meat and Bi.Wherein, Mirabilitum crystallina clearing away heat-fire；Fructus Gardeniae, Radix eriosematis chinensis, Herba Diclipterae Chinensis, shepherd's purse, soil white Liana, Herba Cynanchi Thesioidis, Fructus Trichosanthis, Rhizoma Nephrolepis cordifoliae, Concha Tridacna squamosa meat and Bi, can cooling blood for hemostasis, heat clearing away with the Radix Rehmanniae, Radix Scrophulariae, Cacumen Platycladi, Cortex Moutan etc. Removing toxic substances, with controlling bleeding due to blood-heat；Radix Trichosanthis clearing away heat and promoting production of body fluid, detumescence and apocenosis, for diseases such as consumption of body fluid caused by febrile disease, Radix Ophiopogonis, Fructus Forsythiae, Herba Taraxaci are together With；Herba Lophatheri is used for clearing away heart-fire with the Radix Rehmanniae, Radix Glycyrrhizae, Rhizoma Phragmitis etc.；Herba Commelinae one medicine, is longer than heat clearing away, again can diuresis, Herba Pteridis Multifidae, storage, Herba Taraxaci equivalent is used；Wherein, Herba Commelinae and Herba Lophatheri can clearing away heat and promoting diuresis, effect is similar, but the effect of Herba Commelinae is stronger.Folium Nelumbinis This product bitter in the mouth put down, its gas is the most fragrant, can clearing away summer-heat, again can rise send out spleen sun, hemostasis；Plumula Nelumbinis is bitter, cold, enters heart channel.

The pharmacological property of above-mentioned each raw medicinal material is as follows:

Mirabilitum crystallina: pungent, salty, cold；GUIXIN, stomach, kidney channel.Row calentura when curing mainly, high fever excessive thirst, laryngopharynx swelling and pain, edema, urine Close, aphtha of the mouth and tongue, carbuncle, erysipelas, scald.

Fructus Gardeniae: bitter, cold, nontoxic；GUIXIN warp, Liver Channel, lung meridian, stomach warp, tri-jiao channel.Cure mainly the hot swelling pain of mesh, breast heart intestine and small intestine Big heat, unhappy in the heart, pathogenic heat in the stomach gas.Pathogenic fire purging relieving restlessness, clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body, cooling blood for hemostasis.Calentura is vexed, liver-fire mesh Red, headache, jaundice due to damp-heat, stranguria, dysentery hematuria, aphtha of the mouth and tongue, sore swollen toxin, sprain and swell and ache.

The Radix Rehmanniae: sweet, cold；GUIXIN, liver, kidney channel.Heat clearing away, promote the production of body fluid, moisturize, laxation, removing blood stasis with potent drugs, tissue regeneration promoting, pain relieving, regulating menstruation, removing heat from blood, Hemostasis is invigorated blood circulation.

Cacumen Platycladi: bitter, puckery, cold.Return lung, liver, spleen channel.Cooling blood for hemostasis, growing and blacking hair.For hematemesis and epistaxis, spit blood, just Blood, metrostaxis, heat in blood alopecia, early whitening of beard and hair.

Cortex Moutan: bitter in the mouth, pungent, cold nature, GUIXIN, liver, kidney channel.There is the effect of clearing away heat and cooling blood, promoting blood circulation to remove blood stasis.

Rhizoma Phragmitis: sweet, cold；Return lung meridian, stomach warp.Clearing away heat and promoting production of body fluid, relieving restlessness, preventing or arresting vomiting, diuresis.Cure mainly: for calentura excessive thirst, gastric heat Vomiting, cough due to lung-heat, lung abscess vomiting pus, the puckery pain of pyretic stranguria.Rhizoma Phragmitis is used for gastropyretic vomiting.

Radix Trichosanthis: hardship sweet, micro-, is slightly cold；Attach to the lung and stomach meridians.Clearing away heat and promoting production of body fluid, detumescence and apocenosis.For calentura excessive thirst, lung-heat is dry Coughing, interior-heat is quenched one's thirst, sore swollen toxin.

Herba Lophatheri: sweet, light, cold.GUIXIN, stomach, small intestine meridian.Clearing heat and relieving fidgetness, diuresis.For calentura excessive thirst, hot urination drenches Bitterly, aphtha of the mouth and tongue.

Herba Commelinae: sweet, cold, light；GUIXIN, all warps of liver,spleen,kidney, intestine and small intestine.Main cold and heat subtertian malaria, phlegm retention, fourth swells, and meat disease is puckery Stagnant, infantile erysipelas, mad epilepsy of generating heat, big abdomen feeling of fullness, body face edema due to disorder of QI, hematodiarrhoea, the poison such as dog stings Serpentis, carbuncle.For fever caused by exogenous pathogens, or heat Sexually transmitted disease (STD) heating is not moved back, or laryngopharynx swelling and pain, and the disease such as carbuncle skin infection.For dysuria, edema, or wet enter to bet bladder, little Just diseases such as dripping puckery pain is drenched.

Herba Pteridis Multifidae: hardship light, micro-is cool.Heat clearing away, dampness removing, removing heat from blood.Control bacillary dysentery, enteritis, fever caused by exogenous pathogens, urinary tract infection, leucorrhea, Parotitis, furuncle, eczema." clearing away heat-damp and promoting diuresis, detoxify dysentery relieving, cooling blood for hemostasis.For dysentery, gastroenteritis, hepatitis, urinary system infection, Cat fever, laryngopharynx swelling and pain, leucorrhea, metrorrhagia, pesticide intoxication；Traumatic hemorrhage, burn and scald are controlled in external.

Store: bitter, cold；Return bladder warp.Diuresis, heat clearing away, parasite killing.Cure mainly and control pyretic stranguria, the difficulty in urination, jaundice, the erosion of the vulva, leucorrhea, ascarid Worm, infantile malnutrition, hemorrhoid swell, eczema.

Herba Taraxaci: nature and flavor are sweet, micro-hardship, cold；Return spleen, stomach, kidney three warp.Apply all pyogenic infections from tumour or sore, scabies ruined tinea skin ulcer；Dispeling the wind, disappear all skin ulcers Poison, dissipates scrofula tuberculosis；Stop the least having blood in stool, control the five types of stranguria difficulty in urination, profit bladder.Heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation.Can be used for upper respiratory tract sense Dye, eye conjunctivitis, mumps, hyperglycemia, acute mastitis swells and ache, gastritis, dysentery, hepatitis, cholecystitis, and acute appendicitis is secreted Urine system infects, pelvic inflammatory disease, carbuncle furuncle furuncle, and pharyngitis controls acute mastitis, lymphadenitis, scrofula, furuncle carbuncle toxin, acute conjunctivitis, Cold, fever, acute tonsillitis, acute bronchitis, urinary tract infection.

Folium Nelumbinis: bitter in the mouth is pungent micro-puckery, cool in nature；GUIXIN, liver, spleen channel.Cure mainly summer-heat excessive thirst, dizziness of having a headache, edema, lack of appetite abdomen Swollen, dysentery, leucorrhea, proctoptosis, spit blood, epistaxis, spitting of blood, have blood in stool, metrorrhagia, post partum longtime lochia, traumatic blood stasis.

Plumula Nelumbinis: bitter, cold, nontoxic；GUIXIN, lung, kidney three warp.Clearing away heart-fire, suppressing the hyperactive liver fire, lung-fire, drops in purgation of spleen excess fire.Relieve summer heat and remove Tired, promoting the production of body fluid to quench thirst, control mesh red and swollen.

Radix Ophiopogonis: property hardship sweet, micro-, it is slightly cold；GUIXIN, lung, stomach warp.There is YIN nourishing and the production of body fluid promoting, effect that lung moistening clears away heart-fire, can be used for larynx Numbness pharyngalgia, Tianjin wound is thirsty, and interior-heat is quenched one's thirst, vexed insomnia, dryness of the intestine constipation etc..

Fructus Forsythiae: bitter in the mouth, cold nature；GUIXIN, lung, small intestine meridian.Cure mainly calentura from the beginning of, anemopyretic cold, heating, vexed, throat Swell and ache, the symptom such as acute nephritis, carbuncle sore tumefacting virus.

Radix Scrophulariae: sweet in the mouth, hardship, salty, cold nature, return lung, stomach, kidney channel.There is clearing away heat and cooling blood, eliminating fire and detoxication, effect of YIN nourishing, Cure mainly warm febrile disease and constipation, puckery dim-sighted, the pharynx of mesh are hindered in nutrient blood, fever of the body, excessive thirst, crimson tongue, a speckle, hectic fever due to YIN-deficiency chronic cough, fidgets due to deficiency not awake, Tianjin The cards such as larynx larynx swells and ache, scrofula sucutaneous nodule, skin sore.

Radix Glycyrrhizae: nature and flavor are sweet, flat；Return spleen, stomach, lung meridian.Cold type of pain in main abdomen, controls infantile convulsion, except distention and fullness in the abdomen；Tonification the five internal organs；Make all Poison of drug；Support kidney qi internal injury, make flaccidity；Housewife's human blood drip lumbago；Empty and frequent fever；Add and use it.Can QI invigorating invigorating middle warmer, relieving spasm to stop pain, profit Lung cough-relieving, eliminating fire and detoxication, coordinating the actions of various ingredients in a prescription.

Radix eriosematis chinensis: sweet；Flat.Return lung；Large intestine；Liver Channel.Removing heat from the lung and dissipating phlegm；Promoting the production of body fluid to quench thirst；Detumescence.Main cough due to lung-heat；Lung abscess；Send out Hot excessive thirst；Dysentery；Hydrocele of testis, food stagnation does not disappears；Treating swelling and pain by traumatic injury.

Herba Diclipterae Chinensis: sweet in the mouth；Micro-hardship；Cold in nature.GUIXIN；Liver；Lung meridian.Heat clearing away；Removing heat from blood；Dampness removing；Removing toxic substances.Main cold, fever；Heat Sick speckle；Tell epistaxis；Have blood in stool；Hematuria；Metrorrhagia；Cough due to lung-heat；Laryngopharynx swelling and pain；Liver-heat conjunctival congestion；Infantile convulsion；Dribbling urination；Band Under；Herpes zoster；Carbuncle furuncle furuncle；Serpentis lyssodexis.

: sour, sweet, puckery, flat.Return liver；Stomach warp.Heat-clearing and toxic substances removing, expelling wind and removing dampness.For hepatitis, appendicitis, mastitis, Lung abscess, multiple abscess, rheumatic arthritis；Sore swollen toxin, otitis media, snake bite and insect sting are controlled in external.

Shepherd's purse: sweet in the mouth；Cold in nature.Return lung；Spleen channel.Moistening the lung and resolving the phlegm；Heat-clearing and toxic substances removing.Main xeropulmonary cough；Laryngopharynx swelling and pain；Quench one's thirst； Furuncle ulcerative carbuncle poison；Drug intoxication.

Radix Melothriae Heterophyllae: bitter in the mouth, cold in nature.Return lung, liver, spleen three warp.Removing heat-phlegm, dampness removing, mass dissipating and swelling eliminating.Control heat syndrome cough, dysentery, drench Disease, urinary tract infection, alcoholic jaundice, rheumatic arthralgia, laryngalgia, conjunctival congestion, eczema, carbuncle.

Herba Cynanchi Thesioidis: sweet is flat.Tonifying the lung gas, resolving heat and reducing pathogenic fire, promoting the production of body fluid to quench thirst, anti-inflammatory analgetic.

Fructus Trichosanthis: sweet in the mouth；Micro-hardship；Cold in nature.Return lung；Stomach；Large intestine channel.Removing heat-phlegm；Wide born of the same parents' eliminating stagnation；Moisturize laxation.Main lung-heat Cough；The thoracic obstruction；Quench one's thirst；Constipation；Carbuncle sore tumefacting virus.

Rhizoma Nephrolepis cordifoliae: sweet in the mouth band is puckery, property is put down, nontoxic.Promoting the production of body fluid to quench thirst, liver heat removing, hemostasis.Controlling dysentery of having loose bowels, dry tongue is thirsty, eyeball Upper nebula, traumatic injury internal injury, knife injury is hemorrhage.

Concha Tridacna squamosa meat: sweet in the mouth；Salty；Cold in nature.Yin-nourishing and body fluid promoting；Heat-clearing and toxic substances removing.Main empty win interior-heat；Quench one's thirst；Flaccidity syndrome and arthralgia syndrome；Let out dysentery；Toxic swelling.

Bi: bitter；Flat.Return liver；Stomach；Bladder warp.Wind-damp dispelling；Dampness removing is turbid.Main stranguria marked by chyluria；Nebulousurine；Leukorrhagia；Skin infection；Eczema；Wind Pain of dampness syndrome.

Embodiment is below used to describe embodiments of the present invention in detail, whereby to the present invention how application technology means Solve technical problem, and the process that realizes reaching technique effect can fully understand and implement according to this.

Embodiment 1 Chinese medicine additive

Take Mirabilitum crystallina 33 weight portion, Fructus Gardeniae 11 weight portion, the Radix Rehmanniae 24 weight portion, Cacumen Platycladi 36 weight portion, Cortex Moutan 19 weight Amount part, Rhizoma Phragmitis 21 weight portion, Radix Trichosanthis 12 weight portion, Herba Lophatheri 35 weight portion, Herba Commelinae 29 weight portion, Herba Pteridis Multifidae 38 weight Part, store 14 weight portions, Herba Taraxaci 25 weight portion, Folium Nelumbinis 32 weight portion, Plumula Nelumbinis 17 weight portion, weight portion Radix Ophiopogonis 15, Fructus Forsythiae 16 weight portions, Radix Scrophulariae 39 weight portion, Radix Glycyrrhizae 32 weight portion, Radix eriosematis chinensis 11 weight portion, Herba Diclipterae Chinensis 30 weight portion, 40 weight Part, shepherd's purse 5 weight portion, Radix Melothriae Heterophyllae 17 weight portion, Herba Cynanchi Thesioidis 24 weight portion, Fructus Trichosanthis 8 weight portion, Rhizoma Nephrolepis cordifoliae 17 weight portion, Concha Tridacna squamosa Meat 35 weight portion and Bi 16 weight portion.

Preparation method comprises the following steps:

The first step, is mixed in proportion described each raw medicinal material, and addition relative to the determining alcohol of mixture quality 3 times is The ethanol of 95%, is heated to reflux 2 hours, extracts, and filters and obtains the first extracting solution；Filter the medicinal residues obtained to add relative to institute State the ethanol that determining alcohol is 95% of medicinal residues quality 2 times, be heated to reflux 2 hours, extract, filter and obtain the second extracting solution；By first Extracting solution and the second extracting solution merge, and concentrating under reduced pressure removes alcohol solvent, are dried, it is thus achieved that dry cream；

Second step, is placed in super micron mill pulverizing 2 hours by the dry cream that the first step obtains, and pulverizes, sieves, it is thus achieved that The micropowders of 400 mesh, it is thus achieved that Chinese medicine additive powder.

Embodiment 2 feedstuff

Embodiments provide a kind of feedstuff for preventing and treating chronic type swine fever epidemic disease, the weight portion of each raw material in feedstuff Number is: Testa Tritici 65 weight portion, Semen Maydis 45 weight portion, Semen Tritici aestivi 28 weight portion, Semen setariae 25 weight portion, Amylum Nelumbinis Rhizomatis 19 weight portion, Thallus Laminariae (Thallus Eckloniae) 20 Weight portion, Germinatus Phragmitis 13 weight portion, Citrua paradiai 15 weight portion, Exocarpium Benincasae 17 weight portion, Amaranthus mangostanus L. 14 weight portion, bean cake 21 weight portion, kind Eggplant 30 weight portion, Fructus Luffae 8 weight portion, Semen Nelumbinis 7 weight portion, Pleurotus ostreatus 6 weight portion, vitamin premix 0.5 weight portion, trace element Premix material 0.5 weight portion and Chinese medicine additive 2 weight portion；Wherein in Chinese medicine additive, the ratio of weight and number of each raw medicinal material is: Mirabilitum crystallina 33 weight portion, Fructus Gardeniae 11 weight portion, the Radix Rehmanniae 24 weight portion, Cacumen Platycladi 36 weight portion, Cortex Moutan 19 weight portion, Rhizoma Phragmitis 21 Weight portion, Radix Trichosanthis 12 weight portion, Herba Lophatheri 35 weight portion, Herba Commelinae 29 weight portion, Herba Pteridis Multifidae 38 weight portion, store 14 weight Part, Herba Taraxaci 25 weight portion, Folium Nelumbinis 32 weight portion, Plumula Nelumbinis 17 weight portion, weight portion Radix Ophiopogonis 15, Fructus Forsythiae 16 weight portion, Radix Scrophulariae 39 weight portions, Radix Glycyrrhizae 32 weight portion, Radix eriosematis chinensis 11 weight portion, Herba Diclipterae Chinensis 30 weight portion, 40 weight portions, shepherd's purse 5 weight portion, Radix Melothriae Heterophyllae 17 weight portion, Herba Cynanchi Thesioidis 24 weight portion, Fructus Trichosanthis 8 weight portion, Rhizoma Nephrolepis cordifoliae 17 weight portion, Concha Tridacna squamosa meat 35 weight portion and Bi 16 weight portions.

Its preparation method comprises the following steps:

(1) weigh all Chinese medicine additive mixed grindings according to ratio of weight and number and become 250 mesh fine powders, be prepared as Chinese medicine and add Agent；

(2) take in proportion Testa Tritici, Semen Maydis, Semen Tritici aestivi, Amylum Nelumbinis Rhizomatis, Semen setariae, Thallus Laminariae (Thallus Eckloniae), Germinatus Phragmitis, Citrua paradiai, Exocarpium Benincasae, Amaranthus mangostanus L., bean cake, Fructus Lycopersici esculenti, Fructus Luffae, Semen Nelumbinis, Pleurotus ostreatus, vitamin premix and microelement pre-mix material are pulverized, and grinding particle size is 300mm so that it is fine powder Amount reaches more than 97% that feedstuff is always expected；

(3) feedstuff after described step (3) being pulverized is poured in spraying machine, and in spray, water temperature is 70-88 DEG C, beats Open spraying machine, stirring minute, be continuously heating to 98 DEG C and complete expanded；

(4) the expanded product that pulverising step (3) obtains, adds the Chinese medicine additive that step (1) obtains, obtains mixture, Add the water of the parts by weight 10 parts of the mixture relative to 100 weight portions, put in granulator and pelletize；

(6) pelletize after be dried, baking temperature is 110 DEG C, drying time 40min；Then cool down, pack.

The toxicity test of Chinese medicine additive:

1, trial drug

Choose Mirabilitum crystallina 33g, Fructus Gardeniae 11g, Radix Rehmanniae 24g, Cacumen Platycladi 36g, Cortex Moutan 19g, Rhizoma Phragmitis 21g, Radix Trichosanthis 12g, Herba Lophatheri 35g, Herba Commelinae 29g, Herba Pteridis Multifidae 38g, storage 14g, Herba Taraxaci 25g, Folium Nelumbinis 32g, Plumula Nelumbinis 17g, 15g Radix Ophiopogonis, company Stick up 16g, Radix Scrophulariae 39g, Radix Glycyrrhizae 32g, Radix eriosematis chinensis 11g, Herba Diclipterae Chinensis 30g, 40g, shepherd's purse 5g, Radix Melothriae Heterophyllae 17g, Herba Cynanchi Thesioidis 24g, Fructus Trichosanthis 8g, Rhizoma Nephrolepis cordifoliae 17g, Concha Tridacna squamosa meat 35g and Bi 16g mixing, be ground into powder；Powder will be obtained add in 1400g cold water Soaking 25 hours, with slow fire boiling, decocting time is 1.5 hours, decoction liquor is filtered, it is thus achieved that the first filtrate, collects filtering residue；Will Filter the filtering residue obtained and again add in 1400g cold water, with slow fire boiling 3 times, decoct 1 hour every time, filter and merge filtration Liquid, it is thus achieved that the second filtrate；Merging twice filtrate, concentrating under reduced pressure removes part water, it is thus achieved that decoction, the crude drug concentration of decoction is 3g/ ml。

2, test method: select SD rat, gives in the present invention of variable concentrations (18.0,6.0,2.0g crude drug/kg) The decoction of medicine additive, every day gavage once, continuous 90 days, last be administered latter 24 hours respectively group live and kill 1/2 animal (male and female are each Half), remaining 1/2 animal lives after continuing to observe 2 weeks and kills.The outward appearance of animal, general behavior, food ration, body weight is observed during test Change, is administered latter 90 days and drug withdrawal carries out hematology's (RBC, HB, reticulocyte, PLT, CT, WBC and classification) and blood for 2 weeks Biochemical (AST, ALT, ALP, Glu, BUN, Crca, TP, T.BIL, ALB, CHOL), urine biochemistry, organ coefficient, pathological tissue Etc. index checking.Result of the test shows: the Chinese medicine additive of the present invention is good at high, medium and low dosage treated animal general state, Outward appearance sign, behavioral activity, food-intake and body weight increase change the most without exception；Three dosage groups and matched group hematological examination, Blood biochemical analysis, urine biochemical analysis all between normal range, group without significant difference；Each group main organs histopathological examination Show no obvious abnormalities.These parameters drug withdrawal also had no change after 2 weeks.This test dosage is respectively clinical medicine dose 180,60,20 times, according to the Chinese medicine preparation of the result of the test present invention high, medium and low three dosage (18.0,6.0,2.0g raw Medicine/kg) within continuous 90 days, it is administered rat is had no significant effect, without clear and definite toxicity target organ and sensitive indicator, convalescent period observes also Having no retardance toxic reaction, the dose safety of the Chinese medicine preparation clinical practice of the prompting present invention is higher.

Contrast test

Pig farm, Hebei Handan City, since in April, 2010, in the piglet group of wean (40～60 age in days), Higher mortality rate persistently occurs.When the cardinal symptom of sick pig is body temperature low during height, suffer from diarrhoea (feces is yellowish), become thin, appetite Depressed, secret and diarrhoea the most alternately occurs, and sick pig extremely becomes thin, anemia, hind limb weakness during walking.Some sick pig have sharp ears and extremity go out Existing bluish violet or necrosis.Cuing open the inspection pathological changes in septicemia, intestinal has hyperemia in various degree, hemorrhage, in large intestine and ileum lobe There is obvious ulcer in position.Lymphadenectasis, hyperemia, hemorrhage and edema.Once from some sick pigs internal be separated to escherichia coli, The antibacterial such as Salmonella and streptococcus, but use multiple antibacterials and take corresponding prophylactico-therapeutic measures, produce little effect.Analyse and examine Break as chronic type swine fever.

Choose the ill piglet 100 that 45 ages in days are made a definite diagnosis, 100 ill piglets are randomly divided into two groups, be respectively and implement Example group and matched group, the ill piglet of two groups all without significant difference, has comparability at the aspect such as body weight, the state of an illness.Embodiment group Use with matched group the feedstuff of the embodiment of the present invention 2 and conventional feed to feed ill piglet respectively, feed 7 days continuously, wherein；Right Also need to carry out conventional therapy i.e. 0.4 milliliter/KG of subcutaneous injection hyper-immune serum, once-a-day, astragalin injection intramuscular injection according to group 3ml/ time, 2 times on the one；Simultaneously in feedstuff, add oxytetracycline according to 2:1000 to mix conventional feed and feed, feed conventional feed.Experiment Cycle is 7 days, weighs each group of ill pig weight before and after experiment respectively, and period records recovery from illness situation and the death of ill piglet Number, calculates average daily gain and cure rate, and result is as shown in Table 1 and Table 2.Wherein, cure: spirit is normal, just searching for food drinking-water Often, feces is normal, bouncing, and it is normal that the histoorgans such as inspection liver, intestinal, fabricius bursa, pancreas are cutd open in sampling；Invalid: clinical condition Shape does not improve and even increases the weight of or dead.

1 liang of experimental group piglet average weight synopsis of table

Knowable to the data of table 1: compared with matched group, use the piglet that the feedstuff of the present invention feeds, to piglet 52 age in days Time, its average weight exceeds 1.9kg than the piglet that traditional therapy is treated, and average daily gain exceeds 0.26kg/d.

The therapeutic effect synopsis of 2 liang of experimental group piglets of table

Knowable to the data of table 2: compared with conventional medicament, the feedstuff of the embodiment of the present invention 2 is in treatment chronic type swine fever side Effective in cure notable, cheap, the advantage that has no side effect of mask.

By contrast test: the ill piglet average weight of mixed feed nursing of the embodiment of the present invention 2, cure rate Be superior to matched group, i.e. the feedstuff of the present invention can not only treat swine fever, additionally it is possible to meets the nutritional need of piglet, particularly suitable Nutritional need in the piglet suffering from chronic type swine fever.

Model case

The piglet of 150 40-55 ages in days of Hebei in January, 2013 Handan self-employed pig raiser raising, nearly 27 piglets Appearance is become thin, anemia, and asthenia universalis is often lain prostrate, and gait is the most unable, inappetence, and constipation and diarrhoea are alternately.Cut open inspection pig table Being now splanchnocoel hydrops, visceral pericardium is hemorrhage, and liver turns yellow, and there is volume petechia on surface, and spleen edge infarction, total lymphoid bears water Swell, congested, periphery is hemorrhage.Kidney is khaki, and there is a petechia of needle point size on surface, and medullary substance, renal pelvis portion are hemorrhage, and mucous membrane of urinary bladder has The petechia of being dispersed in property.Mesentery edema, colorectal mucosa is hemorrhage, hemorrhage of tonsil, and larynx myxedema has hemorrhage speckle.Pick up from The spleen of pig farm 5 example disease pig and lymph node, take pathological material of disease suspension point sample on nitrocellulose filter, natural drying;With 10% defat cattle Milk, closes 30 minutes for 37 DEG C;Rinse 3 times with PBS;Enzyme-added mark anti-hog cholera antibody IgG, 37 DEG C are reacted 2 hours;Ibid float Wash;Add DAB colour developing lucifuge to react 15 minutes;Tap water rinse, terminates reaction;Occur that rufous speckle is judged to the positive.

It is diagnosed as chronic type swine fever.Immediately piglet symptom do not occur is isolated raising place.Choose 14 therein Ill piglet, starts to feed the feedstuff of the embodiment of the present invention 2, feeds 7 days, and within the 3rd day, ill piglet symptom is obviously improved, the 5th day 13 piglets are all fully recovered, and after continuing to feed 4 days, compared with sodium selenite, average weight is essentially identical.

The foregoing is only presently preferred embodiments of the present invention, not in order to limit the present invention, all spirit in the present invention and Within principle, any modification, equivalent substitution and improvement etc. made, should be included within the scope of the present invention.

Claims (4)

1. for preventing and treating the mixed feed of chronic type swine fever epidemic disease, it is characterised in that the parts by weight of each raw material in described feedstuff For: Testa Tritici 40-65 weight portion, Semen Maydis 25-45 weight portion, Semen Tritici aestivi 20-32 weight portion, Semen setariae 20-28 weight portion, Amylum Nelumbinis Rhizomatis 15-30 Weight portion, Thallus Laminariae (Thallus Eckloniae) 15-25 weight portion, Germinatus Phragmitis 7-14 weight portion, Citrua paradiai 8-17 weight portion, Exocarpium Benincasae 15-20 weight portion, Amaranthus mangostanus L. 10-19 weight portion, bean cake 10-22 weight portion, Fructus Lycopersici esculenti 15-35 weight portion, Fructus Luffae 7-16 weight portion, Semen Nelumbinis 5-10 weight portion, flat Mushroom 4-9 weight portion, vitamin premix 0.3-0.5 weight portion, microelement pre-mix material 0.3-0.5 weight portion and Chinese medicine additive 2-4 weight portion；

In described Chinese medicine additive, the parts by weight of each raw medicinal material are: Mirabilitum crystallina 23-36 part, Fructus Gardeniae 7-15 part, Radix Rehmanniae 17-35 Part, Cacumen Platycladi 25-40 part, Cortex Moutan 9-25 part, Rhizoma Phragmitis 13-27 part, Radix Trichosanthis 10-28 part, Herba Lophatheri 25-38 part, Herba Commelinae 28-40 part, Herba Pteridis Multifidae 26-39 part, storage 12-32 part, Herba Taraxaci 12-37 part, Folium Nelumbinis 20-35 part, Plumula Nelumbinis 15-28 part, wheat Winter 15-30 part, Fructus Forsythiae 12-25 part, Radix Scrophulariae 25-40 part, Radix Glycyrrhizae 15-32 part, Radix eriosematis chinensis 11-23 part, Herba Diclipterae Chinensis 17-30 part, 26-42 part, shepherd's purse 3-10 part, Radix Melothriae Heterophyllae 15-29 part, Herba Cynanchi Thesioidis 20-37 part, Fructus Trichosanthis 7-23 part, Rhizoma Nephrolepis cordifoliae 11-29 part, Che Giant clam meat 20-38 part and Bi 14-29 part.

Mixed feed for preventing and treating chronic type swine fever epidemic disease the most according to claim 1, it is characterised in that described feedstuff In the parts by weight of each raw material be: Testa Tritici 65 weight portion, Semen Maydis 45 weight portion, Semen Tritici aestivi 28 weight portion, Semen setariae 25 weight portion, Amylum Nelumbinis Rhizomatis 19 weight portions, Thallus Laminariae (Thallus Eckloniae) 20 weight portion, Germinatus Phragmitis 13 weight portion, Citrua paradiai 15 weight portion, Exocarpium Benincasae 17 weight portion, Amaranthus mangostanus L. 14 weight portion, Bean cake 21 weight portion, Fructus Lycopersici esculenti 30 weight portion, Fructus Luffae 8 weight portion, Semen Nelumbinis 7 weight portion, Pleurotus ostreatus 6 weight portion, vitamin premix 0.5 Weight portion, microelement pre-mix material 0.5 weight portion and Chinese medicine additive 2 weight portion.

Mixed feed for preventing and treating chronic type swine fever epidemic disease the most according to claim 1 and 2, it is characterised in that in described In medicine additive, the parts by weight of each raw medicinal material are: Mirabilitum crystallina 33 parts, Fructus Gardeniae 11 parts, 24 parts of the Radix Rehmanniae, Cacumen Platycladi 36 parts, Paeonia suffruticosa Skin 19 parts, Rhizoma Phragmitis 21 parts, Radix Trichosanthis 12 parts, Herba Lophatheri 35 parts, Herba Commelinae 29 parts, Herba Pteridis Multifidae 38 parts, storage 14 parts, Herba Taraxaci 25 Part, 32 parts of Folium Nelumbinis, Plumula Nelumbinis 17 parts, Radix Ophiopogonis 15 parts, Fructus Forsythiae 16 parts, Radix Scrophulariae 39 parts, 32 parts of Radix Glycyrrhizae, Radix eriosematis chinensis 11 parts, Herba Diclipterae Chinensis 30 parts, 40 parts, shepherd's purse 5 parts, Radix Melothriae Heterophyllae 17 parts, Herba Cynanchi Thesioidis 24 parts, Fructus Trichosanthis 8 parts, Rhizoma Nephrolepis cordifoliae 17 parts, Concha Tridacna squamosa meat 35 parts and Bi 16 parts.

4. according to the mixed feed for preventing and treating chronic type swine fever epidemic disease described in any one of claim 1 or 2, it is characterised in that The preparation method of described Chinese medicine additive comprises the following steps:

The first step, is mixed in proportion described each raw medicinal material, and adding relative to the determining alcohol of mixture quality 2～4 times is 85 ～the ethanol of 95%, it is heated to reflux 1～3 hour, extracts, filter and obtain the first extracting solution；Filter the medicinal residues obtained to add relatively In described medicinal residues quality 1～the ethanol that determining alcohol is 85～95% of 2 times, it is heated to reflux 1～3 hour, extracts, filter acquisition the Two extracting solution；First extracting solution and the second extracting solution being merged, concentrating under reduced pressure removes alcohol solvent, is dried, it is thus achieved that dry cream；

Second step, is placed in super micron mill pulverizing 1～2 hour by the dry cream that the first step obtains, and pulverizes, sieves, it is thus achieved that 300 Mesh～the micropowders of 400 mesh, it is thus achieved that Chinese medicine additive powder.