CN102727770A - Pure traditional Chinese medicine composition used for treating swine influenza, and preparation method thereof - Google Patents
Pure traditional Chinese medicine composition used for treating swine influenza, and preparation method thereof Download PDFInfo
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Abstract
The invention relates to a pure traditional Chinese medicine composition used for treating swine influenza. The pure traditional Chinese medicine composition is prepared from mixed components of, by weight: 15-35 parts of Chinese ephedra herb, 15-35 parts of fermented soybean, 15-45 parts of imperatae rhizome, 15-35 parts of semen cassia, 25-45 parts of mung bean, 15-35 parts of dandelion, 15-45 parts of licorice root, 15-45 parts of tangerine peel, 15-35 parts of common knotweed herb, and 15-45 parts of honeysuckle flower. The pure traditional Chinese medicine composition provided by the invention is advantaged in reasonable formula, simple preparation, no toxic or side effect, no pollution, no drug residue, no drug resistance, ultrafine grinding, high bioavailability, and substantial curative effect. As a result of clinical application, the pure traditional Chinese medicine composition has a special effect in treating swine influenza.
Description
Technical field
The present invention relates to pure Chinese medicine composition of treating swine flue and preparation method thereof, belong to the animal field of medicaments, particularly a kind of pure Chinese medicine composition that is specifically designed to the treatment swine flue and preparation method thereof.
Background technology
Swine influenza is called for short influenza, is the infectious disease of the ARI that caused by influenza virus.Clinical manifestation is that heating, cough, asthenia universalis are unable, presents the respiratory inflammation of different characteristics.Be prone to concurrent bronchitis, pneumonia pleuritis and myocarditis etc., increase the case fatality rate of pig.Pathological change is mainly at respiratory apparatus.The mucous hyperemia of nose, pharynx, larynx, trachea and bronchus, swelling, surface are covered with heavy-gravity liquid; Thoracic cavity, pericardial cavity are accumulated and are mixed with cellulosic serosity in a large number; Lungs generation solid lesion, spleen enlargement, lymphadenectasis succulence etc.This disease takes place suddenly, propagates rapidly fiercely, presents popularity, and M & M is all very high, no age, sex and kind difference.All send out throughout the year, but, be one of principal disease of serious harm pig industry more to see in early spring, late fall and the cold season that there was an abrupt change in weather.
This disease almost spreads all over all countries of raising pigs of the world, distributes very extensively.At present, treat this disease the most frequently used be Chinese medicine and antiviral agents and antipyretic analgesic medicine, Chinese medicine is because its prescription is unreasonable or just simple the pulverizing, and particle diameter is excessive, and drug release is slower, causes its bioavailability lower, clinical effectiveness is not fine; Antiviral agents is owing to serious toxic and side effects and drug residue, and the Ministry of Agriculture bans use of; The antipyretic analgesic medicine is owing to have drug residue and be prone to produce drug resistance, its clinical effectiveness worse and worse, and drug residue cause exporting limited healthy with the harm people, thereby make the use of antipyretic analgesic medicine receive very big restriction.
Therefore researching and developing a kind of specific medicament of treating the drug residue free of swine flue, the generation that has no drug resistance is one of this field scientific research technical staff new problem anxious to be solved.
Summary of the invention
The objective of the invention is to overcome above-mentioned weak point, provide that a kind of reasonable recipe, preparation are simple, micronizing, bioavailability are high, effect obviously, have no drug resistance and the pure Chinese medicine composition of effective treatment swine flue of drug residue and preparation method thereof.
Following for realizing the embodiment that above-mentioned purpose the present invention adopted: a kind of pure Chinese medicine composition of treating swine flue, by following component by weight mixed preparing form: Herba Ephedrae 15-35 part, Semen Sojae Preparatum 15-35 part, root of couch grass 15-45 part, Semen Cassiae 15-35 part, Semen phaseoli radiati 25-45 part, Herba Taraxaci 15-35 part, Radix Glycyrrhizae 15-45 part, Pericarpium Citri Reticulatae 15-45 Fen 、 Herba Polygoni Avicularis 15-35 part, Flos Lonicerae 15-45 part.
Said various component optimum ratio amount is: 25 parts in Herba Ephedrae, 25 parts of Semen Sojae Preparatums, 30 parts of root of couch grass, 25 parts of Semen Cassiae, 35 parts in Semen phaseoli radiati, 25 parts of Herba Taraxacis, 30 parts in Radix Glycyrrhizae, Pericarpium Citri Reticulatae 30 25 parts of Fen 、 Herba Polygoni Avicularis, 30 parts of Flos Loniceraes.
A kind of method for preparing of treating the pure Chinese medicine composition of swine flue, carry out as follows:
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing Herba Ephedrae 15-35 part, Semen Sojae Preparatum 15-35 part, root of couch grass 15-45 part, Semen Cassiae 15-35 part, Semen phaseoli radiati 25-45 part by weight, mix 5-10 minute to even;
(3) take by weighing Herba Taraxaci 15-35 part, Radix Glycyrrhizae 15-45 part, Pericarpium Citri Reticulatae 15-45 Fen 、 Herba Polygoni Avicularis 15-35 part, Flos Lonicerae 15-45 part by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
The medicinal property of each component is following:
Herba Ephedrae: little hardship, temperature, suffering, return lung, urinary bladder channel, have the function of the cold expelling that induces sweat, depressed lung-energy dispersing, inducing diuresis to remove edema; Cure mainly affection of exogenous wind-cold, cough, asthma, edema etc.
Semen Sojae Preparatum: sweet, little hardship, suffering, return lung, stomach, small intestine meridian, have relieving the exterior syndrome by diaphoresis, clearing heat for promoting eruption, alleviating distention in middle-JIAO relieving restlessness, the strongly fragrant antidotal function of a surname; Cure mainly headache due to common cold, uncomfortable in chest, typhoid fever etc.
Root of couch grass: sweet, cold, return lung, stomach, small intestine meridian, have removing heat from blood, hemostasis, heat clearing away, diuretic function; Cure mainly calentura excessive thirst, haematemesis, epistaxis, lung-heat dyspnea with rapid respiration, gastric heat hiccup, gonorrhea, dysuria, edema, jaundice etc.
Semen Cassiae: sweet, bitter, salty, be slightly cold, return liver, large intestine channel, have the function of clearing away heat to improve acuity of vision, loosening bowel to relieve constipation, wind-damp dispelling, kidney tonifying; Cure mainly the puckery pain of conjunctival congestion, dizzy, the constipation of headache etc.
Semen phaseoli radiati: sweet, cool, GUIXIN, stomach warp, the function that has heat-clearing and toxic substances removing, relieves summer heat and be good for the stomach; Cure mainly that diarrhea due to damp-heat, detoxifcation protect the liver, antiallergic etc.
Radix Glycyrrhizae: sweet, flat, return lung, the heart, spleen channel, have invigorating the spleen and replenishing QI, expelling phlegm for arresting cough and middle emergency, detoxifcation, coordinating the actions of various ingredients in a prescription, cushion toxicity, strong function; Cure mainly weakness of the spleen and stomach, cough with asthma, poisoning etc.
Herba Polygoni Avicularis: bitter, be slightly cold, return urinary bladder channel, have inducing diuresis for treating stranguria syndrome, parasite killing, itching relieving function; Cure mainly that pyretic stranguria, short urination are red, jaundice due to damp-heat, eczema etc.
Pericarpium Citri Reticulatae: bitter, hot, warm, return lung, spleen channel, have the function of regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm; Cure mainly that appetite minimizing, stomachache, tripe are expanded, had loose bowels, productive cough due to phlegm-damp etc.
Flos Lonicerae: sweet, cold, return lung, the heart, stomach warp, have the function of heat-clearing and toxic substances removing, dispelling wind and heat pathogens; Cure mainly epidemic febrile disease heating, anemopyretic cold, cough due to lung-heat, laryngopharynx swelling and pain, toxic-heat and blood stasis, carbuncle sore tumefacting virus etc.
Herba Taraxaci: bitter, sweet, cold, return liver, stomach warp, have the function of heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, inducing diuresis for treating stranguria syndrome; Cure mainly sore, lung abscess, pharyngalgia, jaundice due to damp-heat, pyretic stranguria etc.
More than all flavor Chinese medicine according to the Chinese medical theory compatible combination, to the clinical symptoms and the pathological change of swine flue, the effect of performance treating both the principal and secondary aspects of a disease.
The invention has the beneficial effects as follows: reasonable recipe, preparation is simple, and substep mixes more even; Chinese medicine composition is pollution-free, no drug residue, have no drug resistance, and cost is low, and it is wide to draw materials, and micronizing, bioavailability are high, the curative effect highly significant.The present invention is according to Chinese veterinarian's traditional theory; Optimize this ten flavors Chinese medicine; And making them form pure Chinese powder medicine according to optimum ratio, clinical practice proves that the treatment swine flue is had specially good effect; And make its product meat reach nuisanceless requirement, the export standard that satisfies product has guaranteed that effectively people's is healthy.
The specific embodiment
Below in conjunction with preferred embodiment, to details are as follows according to the specific embodiment provided by the invention:
Embodiment 1
A kind of pure Chinese medicine composition of treating swine flue and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing 150 parts in Herba Ephedrae, 150 parts of Semen Sojae Preparatums, 150 parts of root of couch grass, 150 parts of Semen Cassiae, 250 parts in Semen phaseoli radiati by weight, mix 5-10 minute to even;
(3) take by weighing 150 parts of Herba Taraxacis, 150 parts in Radix Glycyrrhizae, Pericarpium Citri Reticulatae 150 150 parts of Fen 、 Herba Polygoni Avicularis, 150 parts of Flos Loniceraes by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Embodiment 2
A kind of pure Chinese medicine composition of treating swine flue and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing 250 parts in Herba Ephedrae, 250 parts of Semen Sojae Preparatums, 300 parts of root of couch grass, 250 parts of Semen Cassiae, 350 parts in Semen phaseoli radiati by weight, mix 5-10 minute to even;
(3) take by weighing 250 parts of Herba Taraxacis, 300 parts in Radix Glycyrrhizae, Pericarpium Citri Reticulatae 300 250 parts of Fen 、 Herba Polygoni Avicularis, 300 parts of Flos Loniceraes by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Embodiment 3
A kind of pure Chinese medicine composition of treating swine flue and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing 350 parts in Herba Ephedrae, 350 parts of Semen Sojae Preparatums, 450 parts of root of couch grass, 350 parts of Semen Cassiae, 450 parts in Semen phaseoli radiati by weight, mix 5-10 minute to even;
(3) take by weighing 350 parts of Herba Taraxacis, 450 parts in Radix Glycyrrhizae, Pericarpium Citri Reticulatae 450 350 parts of Fen 、 Herba Polygoni Avicularis, 450 parts of Flos Loniceraes by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Clinical trial:
The clinical experiment animal is selected the 70-100 age in days for use, and laboratory is diagnosed as the ill pig of swine flue, and it is isolated separately raise, the complete feed of feeding, and be divided into 3 groups at random, and 30 every group, 3 groups of feeding environments are identical, and test period is 5 days; The blank group is left intact, and the medicine matched group uses treatment with institute's control drug by specification; Chinese medicine composition group of the present invention can be with the ill pig of product feeding of the present invention etc., and a day dose is: boiled water soaks, and wait temperature and irritate clothes, by the each 200g of product of the present invention, every day 1 time, logotype 3-5 day; Oral back reaches the purpose of treatment disease through gastrointestinal absorption.Computational methods: mortality rate=dead animal number/experimental animal number * 100%, cure rate=healing number of animals/experimental animal number * 100%.Result's (testing the 5th day) when following table is the experiment end.
Table is the situation contrast of the present invention and other medicines treatment swine flue:
| Numbering | Group | Mortality rate % | Cure rate % | Symptom rate % is arranged during end |
| I | The blank group | 50.0 | 10.0 | 40.0 |
| II | Antipyretic and detoxicated diffusing group | 10.0 | 83.3 | 6.7 |
| III | Present composition group | 3.3 | 93.4 | 3.3 |
This clinical effectiveness is through statistical analysis, and present composition treatment group is being compared difference extremely significantly (P＜0.01) with antipyretic and detoxicated diffusing group aspect the cure rate.
Safety testing:
Choose 10 of 70 age in days health pig; 5 times of fillings according to the embodiment of the invention 1 made compositions RD were obeyed 10 days, and during the medication, health pig has no bad or the Deviant Behavior performance; The drinking-water of searching for food is normal, and it is not remarkable that weight increase and blank group (being not administration of health group) are compared difference.
Above-mentioned detailed description of pure Chinese medicine composition of this treatment swine flue and preparation method thereof being carried out with reference to embodiment; Be illustrative rather than determinate; Can enumerate out several embodiment according to institute's limited range; Therefore in the variation and the modification that do not break away under the general plotting of the present invention, should belong within protection scope of the present invention.
Claims (3)
1. pure Chinese medicine composition of treating swine flue, it is characterized in that by following component by weight mixed preparing form: Herba Ephedrae 15-35 part, Semen Sojae Preparatum 15-35 part, root of couch grass 15-45 part, Semen Cassiae 15-35 part, Semen phaseoli radiati 25-45 part, Herba Taraxaci 15-35 part, Radix Glycyrrhizae 15-45 part, Pericarpium Citri Reticulatae 15-45 part, Herba Polygoni Avicularis 15-35 part, Flos Lonicerae 15-45 part.
2. the pure Chinese medicine composition of treatment swine flue according to claim 1, it is characterized in that by following component by weight mixed preparing form: 25 parts in Herba Ephedrae, 25 parts of Semen Sojae Preparatums, 30 parts of root of couch grass, 25 parts of Semen Cassiae, 35 parts in Semen phaseoli radiati, 25 parts of Herba Taraxacis, 30 parts in Radix Glycyrrhizae, Pericarpium Citri Reticulatae 30 25 parts of Fen 、 Herba Polygoni Avicularis, 30 parts of Flos Loniceraes.
3. the method for preparing of the pure Chinese medicine composition of a treatment swine flue according to claim 1 and 2 is characterized in that carrying out as follows:
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing Herba Ephedrae 15-35 part, Semen Sojae Preparatum 15-35 part, root of couch grass 15-45 part, Semen Cassiae 15-35 part, Semen phaseoli radiati 25-45 part by weight, mix 5-10 minute to even;
(3) take by weighing Herba Taraxaci 15-35 part, Radix Glycyrrhizae 15-45 part, Pericarpium Citri Reticulatae 15-45 Fen 、 Herba Polygoni Avicularis 15-35 part, Flos Lonicerae 15-45 part by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201210204209.0A CN102727770B (en) | 2012-06-20 | 2012-06-20 | Pure traditional Chinese medicine composition used for treating swine influenza, and preparation method thereof |
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| CN201210204209.0A CN102727770B (en) | 2012-06-20 | 2012-06-20 | Pure traditional Chinese medicine composition used for treating swine influenza, and preparation method thereof |
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| CN102727770A true CN102727770A (en) | 2012-10-17 |
| CN102727770B CN102727770B (en) | 2014-05-28 |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104147185A (en) * | 2014-07-19 | 2014-11-19 | 扬中牧乐药业有限公司 | Traditional Chinese medicine preparation for treating swine influenza and preparation method thereof |
| CN105639098A (en) * | 2015-12-22 | 2016-06-08 | 山东迅达康生物科技有限公司 | Green feed additive for livestock and preparation method thereof |
| CN105995009A (en) * | 2016-06-23 | 2016-10-12 | 唐三兵 | Feed capable of improving anti-influenza capacity of pigs |
| CN107029135A (en) * | 2017-04-27 | 2017-08-11 | 广西大学 | A kind of formula for treating pig common disease |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101983665A (en) * | 2010-09-20 | 2011-03-09 | 沁源县灵兴养殖专业合作社 | Traditional Chinese medicine for preventing swine influenza |
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2012
- 2012-06-20 CN CN201210204209.0A patent/CN102727770B/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101983665A (en) * | 2010-09-20 | 2011-03-09 | 沁源县灵兴养殖专业合作社 | Traditional Chinese medicine for preventing swine influenza |
Non-Patent Citations (2)
| Title |
|---|
| 李巧云: "猪流感中草药疗法15方", 《河北农民报》 * |
| 肖秀芝: "猪常见病验方", 《吉林畜牧兽医》 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104147185A (en) * | 2014-07-19 | 2014-11-19 | 扬中牧乐药业有限公司 | Traditional Chinese medicine preparation for treating swine influenza and preparation method thereof |
| CN105639098A (en) * | 2015-12-22 | 2016-06-08 | 山东迅达康生物科技有限公司 | Green feed additive for livestock and preparation method thereof |
| CN105995009A (en) * | 2016-06-23 | 2016-10-12 | 唐三兵 | Feed capable of improving anti-influenza capacity of pigs |
| CN107029135A (en) * | 2017-04-27 | 2017-08-11 | 广西大学 | A kind of formula for treating pig common disease |
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| CN102727770B (en) | 2014-05-28 |
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