CN102813756A - Pure traditional Chinese medicine composition for treating bovine influenza and preparation method of pure traditional Chinese medicine composition - Google Patents
Pure traditional Chinese medicine composition for treating bovine influenza and preparation method of pure traditional Chinese medicine composition Download PDFInfo
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Abstract
The invention relates to a pure traditional Chinese medicine composition for treating bovine influenza and a preparation method of the pure traditional Chinese medicine composition. The composition is prepared by mixing the following components by weight: 25-45 parts of folium mori, 15-35 parts of peppermint, 15-35 parts of cyrtomium fortune, 15-35 parts of honeysuckle stem, 15-45 parts of blackberry lily, 15-35 parts of coptis chinensis, 15-45 parts of ligusticum wallichii, 15-45 parts of saposhnikovia divaricata, 25-45 parts of gypsum and 15-45 parts of burdock. The pure traditional Chinese medicine composition for treating bovine influenza has the following beneficial effects: the formula is reasonable, and the preparation is simple; the composition has no toxic and side effects, no pollution, no drug residue and no drug resistance; the materials are subjected to superfine grinding and have high bioavailability; and the pure traditional Chinese medicine composition for treating bovine influenza has very remarkable curative effects and has special effect for treating bovine influenza as shown in clinical application.
Description
Technical field
The present invention relates to pure Chinese medicine composition of treating the cattle influenza and preparation method thereof, belong to the animal field of medicaments, particularly a kind of pure Chinese medicine composition that is specifically designed to treatment cattle influenza and preparation method thereof.
Background technology
Bovine ephemeral flu is called for short influenza, is the infectious disease of the ARI that caused by influenza virus.Clinical manifestation is that heating, cough, asthenia universalis are unable, presents the respiratory inflammation of different characteristics.This disease takes place suddenly, propagates rapidly fiercely, presents popularity, and sickness rate is high, and mortality rate is low, no age, sex and kind difference.All send out throughout the year, but, be one of principal disease of serious harm cattle-raising more to see in early spring, late fall and the cold season that there was an abrupt change in weather.
This disease almost spreads all over all cowboying countries of the world, distributes very extensively.At present, treat this disease the most frequently used be Chinese medicine and antiviral agents and antipyretic analgesic medicine, Chinese medicine is because its prescription is unreasonable or just simple the pulverizing, and particle diameter is excessive, and drug release is slower, causes its bioavailability lower, clinical effectiveness is not fine; Antiviral agents is owing to serious toxic and side effects and drug residue, and the Ministry of Agriculture bans use of; The antipyretic analgesic medicine is owing to have drug residue and be prone to produce drug resistance, its clinical effectiveness worse and worse, and drug residue cause exporting limited healthy with the harm people, thereby make the use of antipyretic analgesic medicine receive very big restriction.
Therefore researching and developing a kind of specific medicament of treating the drug residue free of cattle influenza, the generation that has no drug resistance is one of this field scientific research technical staff new problem anxious to be solved.
Summary of the invention
The objective of the invention is to overcome above-mentioned weak point, provide that a kind of reasonable recipe, preparation are simple, micronizing, bioavailability are high, effect obviously, have no drug resistance and the pure Chinese medicine composition of effective treatment cattle influenza of drug residue and preparation method thereof.
Following for realizing the embodiment that above-mentioned purpose the present invention adopted: a kind of pure Chinese medicine composition of treating the cattle influenza, by following component by weight mixed preparing form: Folium Mori 25-45 part, Herba Menthae 15-35 part, Rhizoma Osmundae 15-35 part, Caulis Lonicerae 15-35 part, Rhizoma Belamcandae 15-45 part, Rhizoma Coptidis 15-35 part, Rhizoma Chuanxiong 15-45 part, windproof 15-45 part, Gypsum Fibrosum 25-45 part, Fructus Arctii 15-45 part.
On the basis of such scheme, said various component optimum ratio amounts are: 30 parts on Folium Mori, 25 parts of Herba Menthaes, 25 parts of Rhizoma Osmundae, 25 parts of Caulis Loniceraes, 30 parts of Rhizoma Belamcandae, 25 parts of Rhizoma Coptidis, 30 parts of Rhizoma Chuanxiongs, windproof 30 parts, 35 parts in Gypsum Fibrosum, 30 parts of Fructus Arctiis.
A kind of method for preparing of treating the pure Chinese medicine composition of cattle influenza, carry out as follows:
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing Folium Mori 25-45 part, Herba Menthae 15-35 part, Rhizoma Osmundae 15-35 part, Caulis Lonicerae 15-35 part, Rhizoma Belamcandae 15-45 part by weight, mix 5-10 minute to even;
(3) take by weighing Rhizoma Coptidis 15-35 part, Rhizoma Chuanxiong 15-45 part, windproof 15-45 part, Gypsum Fibrosum 25-45 part, Fructus Arctii 15-45 part by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
The medicinal property of each component is following:
Folium Mori: sweet, bitter, cold, return lung, Liver Channel, have the function of dispelling wind and heat pathogens, clearing away lung-heat and moistening for dryness, liver heat removing and eyesight improving; Curing mainly anemopyretic cold, cough due to lung-heat, conjunctival congestion sheds tears etc.
Herba Menthae: hot, cool, return lung, Liver Channel, have the function of wind-dispelling heat-dissipating, the cleaning head, sore-throat relieving, rash; Cure mainly affection due to external wind and heat, laryngopharynx swelling and pain, conjunctival congestion, rubella etc.
Rhizoma Osmundae: bitter, cold, return liver, stomach warp, have heat-clearing and toxic substances removing, cooling blood for hemostasis, anthelmintic function; Cure mainly epidemic disease flu, maculae caused by violent heat pathogen, sore swollen toxin, abdominal pain due to worm stagnation etc.
Caulis Lonicerae: sweet, cold, attach to the lung and stomach meridians, have the function of heat-clearing and toxic substances removing, dispelling wind collateral dredging; Cure mainly epidemic febrile disease heating,, toxic-heat and blood stasis, too fat to move skin infection, rheumatic arthralgia, redness and swelling of joints burning pain etc.
Rhizoma Belamcandae: bitter, cold, return lung meridian, have the function of heat-clearing and toxic substances removing, expectorant, sore-throat relieving; Cure mainly cough due to lung-heat, laryngopharynx swelling and pain, accumulation and obstruction of sputum etc.
Rhizoma Coptidis: bitter, cold, return spleen, stomach, large intestine, gallbladder, heart channel, have the function of heat clearing and damp drying, eliminating fire and detoxication; Cure mainly damp-heat dysentery, hyperactivity of heart-fire, excessiveness of stomach-fire, dampness-heat in the liver and gallbladder etc.
Rhizoma Chuanxiong: hot, warm, return gallbladder, liver, pericardium channel, have the function of blood-activating and qi-promoting, wind-expelling pain-stopping; Cure mainly traumatic injury, stagnation of QI-blood, puerperal blood stasis, rheumatic arthralgia etc.
Windproof: hot, sweet, warm, return liver, spleen, urinary bladder channel, have inducing diaphoresis to dispel wind, win function wet, spasmolytic; Cure mainly affection of exogenous wind-cold, anemofrigid-damp arthralgia, rubella pruritus, tetanus etc.
Gypsum Fibrosum: sweet, hot, cold, attach to the lung and stomach meridians, have the function of clearing away heat-fire, promoting the production of body fluid to quench thirst; Cure mainly fever caused by exogenous pathogenic factors, lung-heat dyspnea with rapid and short breath, the greedy drink of gastric heat, high fever coma, manic uneasiness etc.
Fructus Arctii: hot, bitter, cold, attach to the lung and stomach meridians, have the function of dispelling wind and heat pathogens, lung qi dispersing rash, resolving toxin and disinhibiting the throat; Cure mainly affection due to external wind and heat, cough and asthma, laryngopharynx swelling and pain, carbuncle sore tumefacting virus etc.
More than all flavor Chinese medicine according to the Chinese medical theory compatible combination, to the clinical symptoms and the pathological change of cattle influenza, the effect of performance treating both the principal and secondary aspects of a disease.
The invention has the beneficial effects as follows: reasonable recipe, preparation is simple, and substep mixes more even; Chinese medicine composition is pollution-free, no drug residue, have no drug resistance, and cost is low, and it is wide to draw materials, and micronizing, bioavailability are high, the curative effect highly significant.The present invention is according to Chinese veterinarian's traditional theory; Optimize this ten flavors Chinese medicine, and make them form pure Chinese powder medicine according to optimum ratio, clinical practice proves; Treatment cattle influenza there is specially good effect; And make its product meat reach nuisanceless requirement, satisfy the export standard of product, guaranteed that effectively people's is healthy.
The specific embodiment
Below in conjunction with preferred embodiment, to details are as follows according to the specific embodiment provided by the invention:
Embodiment 1
A kind of pure Chinese medicine composition of treating the cattle influenza and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing 250 parts on Folium Mori, 150 parts of Herba Menthaes, 150 parts of Rhizoma Osmundae, 150 parts of Caulis Loniceraes, 150 parts of Rhizoma Belamcandae by weight, mix 5-10 minute to even;
(3) take by weighing 150 parts of Rhizoma Coptidis, 150 parts of Rhizoma Chuanxiongs, windproof 150 parts, 250 parts in Gypsum Fibrosum, 150 parts of Fructus Arctiis by weight, mix 5-10 minute to evenly;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Embodiment 2
A kind of pure Chinese medicine composition of treating the cattle influenza and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing 350 parts on Folium Mori, 250 parts of Herba Menthaes, 250 parts of Rhizoma Osmundae, 250 parts of Caulis Loniceraes, 300 parts of Rhizoma Belamcandae by weight, mix 5-10 minute to even;
(3) take by weighing 250 parts of Rhizoma Coptidis, 300 parts of Rhizoma Chuanxiongs, windproof 300 parts, 350 parts in Gypsum Fibrosum, 300 parts of Fructus Arctiis by weight, mix 5-10 minute to evenly;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Embodiment 3
A kind of pure Chinese medicine composition of treating the cattle influenza and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing 450 parts on Folium Mori, 350 parts of Herba Menthaes, 350 parts of Rhizoma Osmundae, 350 parts of Caulis Loniceraes, 450 parts of Rhizoma Belamcandae by weight, mix 5-10 minute to even;
(3) take by weighing 350 parts of Rhizoma Coptidis, 450 parts of Rhizoma Chuanxiongs, windproof 450 parts, 450 parts in Gypsum Fibrosum, 450 parts of Fructus Arctiis by weight, mix 5-10 minute to evenly;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Clinical trial:
The clinical experiment animal is selected the 200-250 age in days for use, and laboratory is diagnosed as the beef cattle of cattle influenza, and it is isolated separately raise, the complete feed of feeding, and be divided into 3 groups at random, and 20 every group, 3 groups of feeding environments are identical, and test period is 5 days; The blank group is left intact, and the medicine matched group uses treatment with " the cattle GANKANG looses " by specification; Chinese medicine composition group of the present invention can be with product of the present invention (embodiment of the invention 1 prepared compositions) the ill cattle of feeding etc., and a day dose is: boiled water soaks, and wait temperature and irritate clothes, by the each 220g of product of the present invention, every day 1 time, logotype 3-5 day; Oral back reaches the purpose of treatment disease through gastrointestinal absorption.Computational methods: mortality rate=dead animal number/experimental animal number * 100%, cure rate=healing number of animals/experimental animal number * 100%.Result's (testing the 5th day) when following table is the experiment end.
Table is the situation contrast of the present invention and other medicines treatment cattle influenza:
| Numbering | Group | Mortality rate % | Cure rate % | Symptom rate % is arranged during end |
| I | The blank group | 30.0 | 30.0 | 40.0 |
| II | The cattle GANKANG looses and organizes | 10.0 | 80.0 | 10.0 |
| III | Present composition group | 5.0 | 90.0 | 5.0 |
This clinical effectiveness is through statistical analysis, and present composition treatment group is loose to organize with the cattle GANKANG and compared difference extremely significantly (P＜0.01) aspect the cure rate.
Safety testing:
Choose 10 of the healthy beef cattles of 150 ages in days; 5 times of fillings according to the embodiment of the invention 1 made compositions RD were obeyed 5 days; During the medication; Healthy beef cattle has no bad or the Deviant Behavior performance, and the drinking-water of searching for food is normal, and it is not remarkable that weight increase and blank group (being not administration of health group) are compared difference.
Above-mentioned detailed description of pure Chinese medicine composition of this treatment cattle influenza and preparation method thereof being carried out with reference to embodiment; Be illustrative rather than determinate; Can enumerate out several embodiment according to institute's limited range; Therefore in the variation and the modification that do not break away under the general plotting of the present invention, should belong within protection scope of the present invention.
Claims (3)
1. pure Chinese medicine composition of treating the cattle influenza, it is characterized in that by following component by weight mixed preparing form: Folium Mori 25-45 part, Herba Menthae 15-35 part, Rhizoma Osmundae 15-35 part, Caulis Lonicerae 15-35 part, Rhizoma Belamcandae 15-45 part, Rhizoma Coptidis 15-35 part, Rhizoma Chuanxiong 15-45 part, windproof 15-45 part, Gypsum Fibrosum 25-45 part, Fructus Arctii 15-45 part.
2. the pure Chinese medicine composition of treatment according to claim 1 cattle influenza, it is characterized in that by following component by weight mixed preparing form: 30 parts on Folium Mori, 25 parts of Herba Menthaes, 25 parts of Rhizoma Osmundae, 25 parts of Caulis Loniceraes, 30 parts of Rhizoma Belamcandae, 25 parts of Rhizoma Coptidis, 30 parts of Rhizoma Chuanxiongs, windproof 30 parts, 35 parts in Gypsum Fibrosum, 30 parts of Fructus Arctiis.
3. the method for preparing of the pure Chinese medicine composition of a treatment according to claim 1 and 2 cattle influenza is characterized in that carrying out as follows:
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing Folium Mori 25-45 part, Herba Menthae 15-35 part, Rhizoma Osmundae 15-35 part, Caulis Lonicerae 15-35 part, Rhizoma Belamcandae 15-45 part by weight, mix 5-10 minute to even;
(3) take by weighing Rhizoma Coptidis 15-35 part, Rhizoma Chuanxiong 15-45 part, windproof 15-45 part, Gypsum Fibrosum 25-45 part, Fructus Arctii 15-45 part by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
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| CN201210271978.2A CN102813756B (en) | 2012-08-02 | 2012-08-02 | Pure traditional Chinese medicine composition for treating bovine influenza and preparation method of pure traditional Chinese medicine composition |
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| CN102813756A true CN102813756A (en) | 2012-12-12 |
| CN102813756B CN102813756B (en) | 2014-11-12 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103479918A (en) * | 2013-09-24 | 2014-01-01 | 田光波 | Pharmaceutical composition capable of preventing and curing influenza A (H1N1) |
| CN105231009A (en) * | 2015-11-05 | 2016-01-13 | 农鑫高科（北京）科技开发有限公司 | Feed preventing cattle flu |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1380098A (en) * | 2002-05-20 | 2002-11-20 | 张勇飞 | Anti-infection compound preparation and its preparation method |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1380098A (en) * | 2002-05-20 | 2002-11-20 | 张勇飞 | Anti-infection compound preparation and its preparation method |
Non-Patent Citations (1)
| Title |
|---|
| 章国忠等: "主治牛流感方剂的配伍技巧", 《中兽医学杂志》 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103479918A (en) * | 2013-09-24 | 2014-01-01 | 田光波 | Pharmaceutical composition capable of preventing and curing influenza A (H1N1) |
| CN103479918B (en) * | 2013-09-24 | 2015-04-29 | 田光波 | Pharmaceutical composition capable of preventing and curing influenza A (H1N1) |
| CN105231009A (en) * | 2015-11-05 | 2016-01-13 | 农鑫高科（北京）科技开发有限公司 | Feed preventing cattle flu |
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