CN102813809A - Pure traditional Chinese medicine composition for treating chronic respiratory disease of poultry as well as preparation method thereof - Google Patents

Pure traditional Chinese medicine composition for treating chronic respiratory disease of poultry as well as preparation method thereof Download PDF

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CN102813809A
CN102813809A CN201210271980XA CN201210271980A CN102813809A CN 102813809 A CN102813809 A CN 102813809A CN 201210271980X A CN201210271980X A CN 201210271980XA CN 201210271980 A CN201210271980 A CN 201210271980A CN 102813809 A CN102813809 A CN 102813809A
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chinese medicine
medicine composition
radix
herba
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CN102813809B (en
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周庆福
刘文利
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Qingdao Lvman Bioengineering Co Ltd
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Qingdao Lvman Bioengineering Co Ltd
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Abstract

The invention relates to a pure traditional Chinese medicine composition for treating chronic respiratory disease of poultry as well as preparation method of the pure traditional Chinese medicine composition. The pure traditional Chinese medicine composition is prepared by mixing the following raw materials by weight: 15-35 parts of cordate houttuynia, 15-35 parts of liquorice, 15-25 parts of radix ophiopogonis, 15-25 parts of almond, 15-35 parts of pinellia ternata, 25-35 parts of dandelion, 15-35 parts of peppermint, 15-35 parts of subprostrate sophora, 15-35 parts of snake gourd fruit and 25-45 parts of astragalus mongholicus. The pure traditional Chinese medicine composition has the beneficial effects of being reasonable in formula and easy to prepare, having no toxic side effect, no medicine residue and no medicine resistance, being remarkable in treatment effect and having clinically proven special effect for treating the chronic respiratory disease of the poultry.

Description

A kind of pure Chinese medicine composition of treating the poultry chronic respiratory tract disease and preparation method thereof
Technical field
The present invention relates to a kind of pure Chinese medicine composition of treating the poultry chronic respiratory tract disease and preparation method thereof, belong to the animal field of medicaments, particularly a kind of pure Chinese medicine composition that is specifically designed to treatment poultry chronic respiratory tract disease and preparation method thereof.
Background technology
The poultry chronic respiratory tract disease mainly is a kind of common epidemic disease that is caused by deteriorated blood property mycoplasma, and clinical manifestation is a characteristic with infection poultry breathing hello sound, cough, stream nose liquid; Pathological change shows that mainly trachea and bronchus have serosity or mucus exudate, airsacculitis, pericarditis, perihepatitis etc.This disease is very harmful to poultry farming.
At present; Treat this disease the most frequently used be various antibacterials, like oxytetracycline, chloromycetin, streptomycin, quinolones etc. and since antibacterials generally have toxic and side effects strong be prone to produce shortcoming such as drug resistance; Decline evident in efficacy; And drug residue in animal body, and its meat does not reach nuisanceless requirement, influences the outlet of poultry product and people's physical and mental health.Chinese medicine is because powder particle diameter is big, and bioavailability is low, and onset is slower, and effect is not very desirable.
Therefore the medicine of researching and developing a kind of effective treatment poultry chronic respiratory tract disease is one of this field scientific research technical staff new problem anxious to be solved.
Summary of the invention
The objective of the invention is to overcome above-mentioned weak point, provide a kind of reasonable recipe, preparation simple, have no side effect, drug residue free, have no drug resistance, effectively treat pure Chinese medicine composition of poultry chronic respiratory tract disease and preparation method thereof.
Following for realizing the embodiment that above-mentioned purpose the present invention adopted: a kind of pure Chinese medicine composition of treating the poultry chronic respiratory tract disease, by following component by weight mixed preparing form: Herba Houttuyniae 15-35 part, Radix Glycyrrhizae 15-35 part, Radix Ophiopogonis 15-25 part, Semen Armeniacae Amarum 15-25 part, Rhizoma Pinelliae 15-35 part, Herba Taraxaci 25-35 part, Herba Menthae 15-35 part, Radix Sophorae Tonkinensis 15-35 part, Fructus Trichosanthis 15-35 part, Radix Astragali 25-45 part.
On the basis of such scheme, said various component optimum ratio amounts are: 25 parts of Herba Houttuyniae, 25 parts in Radix Glycyrrhizae, 20 parts of Radix Ophiopogonis, 20 parts in Semen Armeniacae Amarum, 25 parts of the Rhizoma Pinelliaes, 30 parts of Herba Taraxacis, 25 parts of Herba Menthaes, 25 parts of Radix Sophorae Tonkinensiss, 25 parts of Fructus Trichosanthis, 30 parts of the Radixs Astragali.
A kind of method for preparing of treating the pure Chinese medicine composition of poultry chronic respiratory tract disease, carry out as follows:
(1) Chinese medicine of respectively distinguishing the flavor of in the prescription is carried out respectively crossing 700 mesh sieves after the micronizing;
(2) take by weighing Herba Houttuyniae 15-35 part, Radix Glycyrrhizae 15-35 part, Radix Ophiopogonis 15-25 part, Semen Armeniacae Amarum 15-25 part, Rhizoma Pinelliae 15-35 part by weight, mix 5-10 minute to evenly;
(3) take by weighing Herba Taraxaci 25-35 part, Herba Menthae 15-35 part, Radix Sophorae Tonkinensis 15-35 part, Fructus Trichosanthis 15-35 part, Radix Astragali 25-45 part by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
The medicinal property of each component is following:
Herba Houttuyniae: hot, be slightly cold, return lung meridian, have functions such as heat-clearing and toxic substances removing, detumescence and apocenosis, inducing diuresis for treating stranguria syndrome, cure mainly dysentery, intestinal Huang, lung abscess, acute mastitis, stranguria with turbid discharge etc.
Radix Glycyrrhizae: sweet, flat, return lung, the heart, spleen channel, have invigorating the spleen and replenishing QI, expelling phlegm for arresting cough and middle emergency, detoxifcation, coordinating the actions of various ingredients in a prescription, cushion toxicity, strong function; Cure mainly weakness of the spleen and stomach, cough with asthma, poisoning.
Radix Ophiopogonis: bitter, sweet, cold, return lung, the heart, stomach warp, have the function that YIN nourishing and the production of body fluid promoting, lung moistening clear away heart-fire; Cure mainly interior-heat caused by deficiency of YIN, dryness of the lung dry cough, dryness of the intestine constipation etc.
Semen Armeniacae Amarum: bitter, tepor, return lung, large intestine channel, have the function of relieving cough and asthma, loosening bowel to relieve constipation; Cure mainly cough and asthma, dryness of the intestine constipation etc.
The Rhizoma Pinelliae: hot, warm, return spleen, stomach, lung meridian, have the function of drying dampness to eliminate phlegm; Cure mainly damp-phlegm cough with asthma etc.
Herba Taraxaci: bitter, sweet, cold, return liver, stomach warp, have the function of heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, inducing diuresis for treating stranguria syndrome; Cure mainly sore, lung abscess, pharyngalgia, jaundice due to damp-heat, pyretic stranguria etc.
Herba Menthae: hot, cool, return lung, Liver Channel, have the function of wind-dispelling heat-dissipating, the cleaning head, sore-throat relieving, rash; Cure mainly affection due to external wind and heat, laryngopharynx swelling and pain, conjunctival congestion, rubella etc.
Radix Sophorae Tonkinensis: bitter, cold, attach to the lung and stomach meridians, have the function of heat-clearing and toxic substances removing, detumescence sore-throat relieving, expelling phlegm for arresting cough; Cure mainly laryngopharynx swelling and pain, lung-heat cough with asthma, the yellow furunculosis of skin ulcer etc.
Fructus Trichosanthis: sweet, bitter, cold, return lung, stomach, large intestine channel, have the function of removing heat-phlegm, promoting the circulation of QI eliminating stagnation, moistening dryness for relaxing bowels; Cure mainly cough due to lung-heat, chest and diaphragm pain, acute mastitis, feces drying etc.
The Radix Astragali: sweet, tepor, return spleen, lung meridian, have the function of tonifying Qi and lifting yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, expelling pus and toxin by strengthening QI, expelling pus and promoting granulation; Curing mainly asthenia of pulmonosplenic qi, sinking of QI of middle-JIAO, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle sore difficultly bursts, bursts for a long time and do not hold back etc.
More than all herbal medicines according to the theoretical compatible combination of medicine, to the paathogenic factor and the pathological change of poultry chronic respiratory tract disease, the effect of performance treating both the principal and secondary aspects of a disease.
The invention has the beneficial effects as follows: reasonable recipe, preparation is simple, and substep mixes more even; Pure Chinese medicine composition has no side effect, drug residue free, have no drug resistance.The clinical practice proof has specially good effect to treatment poultry chronic respiratory tract disease.
The specific embodiment
Below in conjunction with preferred embodiment, to details are as follows according to the specific embodiment provided by the invention:
Embodiment 1
A kind of pure Chinese medicine composition of treating the poultry chronic respiratory tract disease and preparation method thereof: carry out as follows: (every part by 10g)
(1) Chinese medicine of respectively distinguishing the flavor of in the prescription is carried out respectively crossing 700 mesh sieves after the micronizing;
(2) take by weighing 150 parts of Herba Houttuyniae, 150 parts in Radix Glycyrrhizae, 150 parts of Radix Ophiopogonis, 150 parts in Semen Armeniacae Amarum, 150 parts of the Rhizoma Pinelliaes by weight, mix 5-10 minute to even;
(3) take by weighing 250 parts of Herba Taraxacis, 150 parts of Herba Menthaes, 150 parts of Radix Sophorae Tonkinensiss, 150 parts of Fructus Trichosanthis, 250 parts of the Radixs Astragali by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Embodiment 2
A kind of pure Chinese medicine composition of treating the poultry chronic respiratory tract disease and preparation method thereof: carry out as follows: (every part by 10g)
(1) Chinese medicine of respectively distinguishing the flavor of in the prescription is carried out respectively crossing 700 mesh sieves after the micronizing;
(2) take by weighing 250 parts of Herba Houttuyniae, 250 parts in Radix Glycyrrhizae, 200 parts of Radix Ophiopogonis, 200 parts in Semen Armeniacae Amarum, 250 parts of the Rhizoma Pinelliaes by weight, mix 5-10 minute to even;
(3) take by weighing 300 parts of Herba Taraxacis, 250 parts of Herba Menthaes, 250 parts of Radix Sophorae Tonkinensiss, 250 parts of Fructus Trichosanthis, 350 parts of the Radixs Astragali by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Embodiment 3
A kind of pure Chinese medicine composition of treating the poultry chronic respiratory tract disease and preparation method thereof: carry out as follows: (every part by 10g)
(1) Chinese medicine of respectively distinguishing the flavor of in the prescription is carried out respectively crossing 700 mesh sieves after the micronizing;
(2) take by weighing 350 parts of Herba Houttuyniae, 350 parts in Radix Glycyrrhizae, 250 parts of Radix Ophiopogonis, 250 parts in Semen Armeniacae Amarum, 350 parts of the Rhizoma Pinelliaes by weight, mix 5-10 minute to even;
(3) take by weighing 350 parts of Herba Taraxacis, 350 parts of Herba Menthaes, 350 parts of Radix Sophorae Tonkinensiss, 350 parts of Fructus Trichosanthis, 450 parts of the Radixs Astragali by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Clinical trial:
The clinical experiment animal selects for use 20 ages in days, body weight at 0.8kg-1.0kg, and laboratory is diagnosed as the ill broiler of poultry chronic respiratory tract disease.Ill broiler is isolated raising separately, the complete feed of feeding, and be divided into 3 groups at random, and 100 every group, 3 groups of feeding environments are identical, and experimental period was carried out 5 days altogether; The blank group is left intact, and the medicine matched group uses treatment with institute's control drug by its description; Present composition group is with product of the present invention (embodiment of the invention 1 prepared compositions) the ill broiler of feeding, and a day dose is: 400 kilograms are fed or drunk water to per 100 gram present composition spices, every day 1-2 time for 220 kilograms; Oral back reaches the purpose of treatment disease through gastrointestinal absorption.Computational methods: mortality rate=dead animal number/experimental animal number * 100%, cure rate=healing number of animals/experimental animal number * 100%.Result's (testing the 5th day) when following table is the experiment end.
Table is the situation contrast of the present invention and other medicines treatment chronic respiratory disease:
Numbering Group Mortality rate % Cure rate % Symptom rate % is arranged during end
I The blank group 10.0 57.0 33.0
II The doxycycline hydrochloride group 3.0 80.0 17.0
III Present composition group 3.0 90.0 7.0
This clinical effectiveness is through statistical analysis, and present composition group is being compared difference extremely significantly (P<0.01) with the doxycycline hydrochloride group aspect the cure rate.
Safety testing:
Choose 60 of the healthy broiler of 20 ages in days; According to 5 times of spices of the embodiment of the invention 1 made pure Chinese medicine composition RD or drank water 5 days; During the medication; Healthy broiler has no bad or the Deviant Behavior performance, and the drinking-water of searching for food is normal, and it is not remarkable that weight increase and blank group (being not administration of health group) are compared difference.
Above-mentioned detailed description of pure Chinese medicine composition of this treatment poultry chronic respiratory tract disease and preparation method thereof being carried out with reference to embodiment; Be illustrative rather than determinate; Can enumerate out several embodiment according to institute's limited range; Therefore in the variation and the modification that do not break away under the general plotting of the present invention, should belong within protection scope of the present invention.

Claims (3)

1. pure Chinese medicine composition of treating the poultry chronic respiratory tract disease, it is characterized in that by following component by weight mixed preparing form: Herba Houttuyniae 15-35 part, Radix Glycyrrhizae 15-35 part, Radix Ophiopogonis 15-25 part, Semen Armeniacae Amarum 15-25 part, Rhizoma Pinelliae 15-35 part, Herba Taraxaci 25-35 part, Herba Menthae 15-35 part, Radix Sophorae Tonkinensis 15-35 part, Fructus Trichosanthis 15-35 part, Radix Astragali 25-45 part.
2. the pure Chinese medicine composition of treatment according to claim 1 poultry chronic respiratory tract disease, it is characterized in that by following component by weight mixed preparing form: 25 parts of Herba Houttuyniae, 25 parts in Radix Glycyrrhizae, 20 parts of Radix Ophiopogonis, 20 parts in Semen Armeniacae Amarum, 25 parts of the Rhizoma Pinelliaes, 30 parts of Herba Taraxacis, 25 parts of Herba Menthaes, 25 parts of Radix Sophorae Tonkinensiss, 25 parts of Fructus Trichosanthis, 30 parts of the Radixs Astragali.
3. the method for preparing of the pure Chinese medicine composition of a treatment according to claim 1 and 2 poultry chronic respiratory tract disease is characterized in that carrying out as follows:
(1) Chinese medicine of respectively distinguishing the flavor of in the prescription is carried out respectively crossing 700 mesh sieves after the micronizing;
(2) take by weighing Herba Houttuyniae 15-35 part, Radix Glycyrrhizae 15-35 part, Radix Ophiopogonis 15-25 part, Semen Armeniacae Amarum 15-25 part, Rhizoma Pinelliae 15-35 part by weight, mix 5-10 minute to evenly;
(3) take by weighing Herba Taraxaci 25-35 part, Herba Menthae 15-35 part, Radix Sophorae Tonkinensis 15-35 part, Fructus Trichosanthis 15-35 part, Radix Astragali 25-45 part by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
CN201210271980.XA 2012-08-02 2012-08-02 Pure traditional Chinese medicine composition for treating chronic respiratory disease of poultry as well as preparation method thereof Expired - Fee Related CN102813809B (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105168516A (en) * 2015-10-13 2015-12-23 钟云仙 Compound Chinese herbal medicinal powder for treating chronic respiratory disease of livestock and poultry and preparation method of compound Chinese herbal medicinal powder
CN105497483A (en) * 2015-12-22 2016-04-20 山东迅达康生物科技有限公司 Pure traditional Chinese medicine composition for preventing and treating respiratory diseases of livestock and preparation method of pure traditional Chinese medicine composition
CN105639098A (en) * 2015-12-22 2016-06-08 山东迅达康生物科技有限公司 Green feed additive for livestock and preparation method thereof
CN111838417A (en) * 2020-07-31 2020-10-30 李志刚 Traditional Chinese medicine feed additive and feed for preventing and treating respiratory system diseases of livestock and poultry and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102240329A (en) * 2011-07-01 2011-11-16 佛山科学技术学院 Chinese medicinal preparation for preventing and treating livestock lung heat syndrome
CN102258614A (en) * 2011-07-15 2011-11-30 青岛绿曼生物工程有限公司 Compound propolis composition for treating white diarrhea and chronic respiratory disease and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102240329A (en) * 2011-07-01 2011-11-16 佛山科学技术学院 Chinese medicinal preparation for preventing and treating livestock lung heat syndrome
CN102258614A (en) * 2011-07-15 2011-11-30 青岛绿曼生物工程有限公司 Compound propolis composition for treating white diarrhea and chronic respiratory disease and preparation method thereof

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105168516A (en) * 2015-10-13 2015-12-23 钟云仙 Compound Chinese herbal medicinal powder for treating chronic respiratory disease of livestock and poultry and preparation method of compound Chinese herbal medicinal powder
CN105497483A (en) * 2015-12-22 2016-04-20 山东迅达康生物科技有限公司 Pure traditional Chinese medicine composition for preventing and treating respiratory diseases of livestock and preparation method of pure traditional Chinese medicine composition
CN105639098A (en) * 2015-12-22 2016-06-08 山东迅达康生物科技有限公司 Green feed additive for livestock and preparation method thereof
CN111838417A (en) * 2020-07-31 2020-10-30 李志刚 Traditional Chinese medicine feed additive and feed for preventing and treating respiratory system diseases of livestock and poultry and preparation method thereof

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