CN111838417A - Traditional Chinese medicine feed additive and feed for preventing and treating respiratory system diseases of livestock and poultry and preparation method thereof - Google Patents

Traditional Chinese medicine feed additive and feed for preventing and treating respiratory system diseases of livestock and poultry and preparation method thereof Download PDF

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CN111838417A
CN111838417A CN202010757299.0A CN202010757299A CN111838417A CN 111838417 A CN111838417 A CN 111838417A CN 202010757299 A CN202010757299 A CN 202010757299A CN 111838417 A CN111838417 A CN 111838417A
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parts
livestock
chinese medicine
traditional chinese
feed
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李志刚
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/30Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/20Animal feeding-stuffs from material of animal origin
    • A23K10/26Animal feeding-stuffs from material of animal origin from waste material, e.g. feathers, bones or skin
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/30Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • A23K10/37Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms from waste material
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/158Fatty acids; Fats; Products containing oils or fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • A61K36/342Adenophora
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/42Cucurbitaceae (Cucumber family)
    • A61K36/428Trichosanthes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/78Saururaceae (Lizard's-tail family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8966Fritillaria, e.g. checker lily or mission bells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/10Expectorants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/70Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in livestock or poultry
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P60/00Technologies relating to agriculture, livestock or agroalimentary industries
    • Y02P60/80Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
    • Y02P60/87Re-use of by-products of food processing for fodder production

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  • Health & Medical Sciences (AREA)
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  • Chemical & Material Sciences (AREA)
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Abstract

The invention relates to the technical field of feed additives, in particular to a traditional Chinese medicine feed additive for preventing and treating respiratory diseases of livestock and poultry, a feed and a preparation method. The feed additive contains cortex Mori, pericarpium Citri Tangerinae, Bulbus Fritillariae Cirrhosae, fructus Trichosanthis, herba Houttuyniae, radix Adenophorae, Atractylodis rhizoma and Glycyrrhrizae radix, and can not only treat various respiratory diseases of livestock and fowl, but also regulate the balance of organs in livestock and fowl.

Description

Traditional Chinese medicine feed additive and feed for preventing and treating respiratory system diseases of livestock and poultry and preparation method thereof
Technical Field
The invention relates to the technical field of feeds, in particular to a traditional Chinese medicine feed additive for preventing and treating respiratory diseases of livestock and poultry, a feed and a preparation method.
Background
Respiratory diseases are common diseases of livestock and poultry. Respiratory diseases of livestock and poultry are generally caused by viral, bacterial or parasitic infections, such as influenza secondary, pseudorabies secondary, actinobacillus pleuropneumoniae infection, pasteurella infection and the like. Once the respiratory diseases of the livestock and the poultry are controlled improperly, large-area infection can be caused, complications and even death can be easily caused when the immunity of the livestock and the poultry is reduced, and huge economic loss is brought to the breeding industry. At the present stage, florfenicol, tilmicosin, doxycycline, azithromycin and other antibacterial chemical medicines are mostly adopted for feeding or injection in the treatment, and unreasonable medication not only causes medicine waste and delays the best treatment time, but also easily causes toxic and side effects, causes liver and kidney injury of livestock and poultry, causes drug resistance of the livestock and poultry, causes a large amount of medicine residues in the livestock and poultry bodies, and further threatens the health of the crowd eating the livestock and poultry.
Disclosure of Invention
Aiming at the technical problems that treatment of respiratory diseases by antibacterial chemical drugs can cause liver and kidney injury of livestock and poultry, drug resistance is generated and drug residues are caused in the prior art, the invention provides a traditional Chinese medicine feed additive for preventing and treating respiratory diseases of livestock and poultry, a feed and a preparation method thereof.
In order to achieve the purpose of the invention, the embodiment of the invention adopts the following technical scheme:
on one hand, the embodiment of the invention provides a traditional Chinese medicine feed additive for preventing and treating respiratory diseases of livestock and poultry, which comprises the following raw materials in parts by weight: 10-15 parts of cortex mori, 3-5 parts of orange peel, 1-3 parts of fritillaria cirrhosa, 3-5 parts of snakegourd fruit, 3-5 parts of houttuynia cordata, 5-10 parts of adenophora stricta, 5-10 parts of bighead atractylodes rhizome and 1-3 parts of liquorice.
The traditional Chinese medicine feed additive is a traditional Chinese medicine prescription with the effects of strengthening spleen and replenishing qi, eliminating dampness and phlegm, inducing diuresis to alleviate edema, freeing lung and relieving asthma, eliminating carbuncle and expelling pus, inducing diuresis for treating strangurtia, clearing away heat and toxic materials, and relieving spasm and pain, can treat respiratory system diseases of livestock and poultry caused by various reasons, including intractable respiratory system diseases, has no toxic or side effect, does not generate drug resistance, and can comprehensively regulate the comprehensive balance of each organ in the livestock and poultry body and improve the immunity of the organism.
In the prescription, the mulberry bark is cold in nature, enters lung and spleen channels, purges lung and relieves asthma, and induces diuresis to alleviate edema; orange peel is warm in nature, and has effects of invigorating spleen and lung channels, regulating qi, regulating middle warmer, eliminating dampness, and eliminating phlegm; bulbus Fritillariae Cirrhosae is slightly cold in nature, enters lung and heart channels, and has effects of clearing heat, moistening lung, eliminating phlegm, and relieving cough; snakegourd fruit is cold in nature, enters lung, stomach and large intestine channels, clears heat and washes phlegm, relieves chest stuffiness and dissipates stagnation, and moistens dryness and smoothes intestines. The formula takes the root bark of white mulberry, the orange peel, the unibract fritillary bulb and the snakegourd fruit as monarch drugs, has the effects of clearing heat and reducing phlegm, and can be used for treating heat cough and phlegm, retention of fluid in the lung, fullness and dyspnea with urgency and edema.
The cordate houttuynia, which is slightly cold in nature, enters lung meridian, clears away heat and toxic materials, eliminates carbuncle and pus, induces diuresis and treats stranguria, is a ministerial drug in the formula and is used for treating heat-toxin sores and ulcers, cough due to lung heat, thick phlegm and edema.
The root of straight ladybell is cool in nature and slightly cold in nature, enters lung and stomach channels, nourishes yin and clears heat, tonifies liver and moistens lung, eliminates phlegm and stops cough, benefits stomach and promotes fluid production, and is used as an adjuvant drug in the formula for dry cough and thirst.
The bighead atractylodes rhizome is warm in nature, enters spleen and stomach channels, strengthens spleen and tonifies qi, eliminates dampness and promotes diuresis, and benefits stomach and regulates middle warmer; the liquorice has neutral nature, enters heart channel, lung channel, spleen channel and stomach channel, supplements qi and tonifies middle energizer, clears away heat and toxic material, eliminates phlegm and stops cough, relieves spasm and pain, and harmonizes the property of the medicine. The combination of the atractylodes and the liquorice is used as a messenger drug, can tonify qi and invigorate spleen, and is used for treating spleen qi weakness, poor appetite, loose stool, lassitude, hypodynamia and edema.
The prescription takes the root bark of white mulberry, the orange peel, the bulbus fritillariae cirrhosae and the snakegourd fruit as monarch drugs, and has remarkable functions of clearing heat and reducing phlegm; the houttuynia cordata is taken as a ministerial drug, so that the effects of clearing heat and eliminating phlegm can be synergistically enhanced, and symptoms can be quickly eliminated; the root of straight ladybell not only clears heat and reduces phlegm, but also can nourish yin, so that the lung moistening effect of the formula is further enhanced. The atractylodes macrocephala koidz and the liquorice tonify qi and strengthen the spleen, can eliminate edema of sick and sick livestock caused by respiratory system diseases, improve the absorption of nutrient components and promote the recovery of organisms. The prescription emphasizes the functions of nourishing yin, clearing heat, eliminating phlegm, invigorating qi, relieving swelling and detoxifying through the compatibility of the components, and integrates the functions of resisting bacteria, diminishing inflammation, detoxifying, dredging orifices, relieving cough and asthma, counteracting toxic substances, detoxifying, relieving fever and easing pain.
Preferably, the traditional Chinese medicine additive comprises the following raw materials in parts by weight: 11-13 parts of cortex mori, 3.5-4.5 parts of orange peel, 1.5-2.5 parts of bulbus fritillariae cirrhosae, 3.5-4.5 parts of fructus trichosanthis, 3.5-4.5 parts of houttuynia cordata, 6-8 parts of adenophora stricta, 7-9 parts of rhizoma atractylodis macrocephalae and 1.5-2.5 parts of liquorice.
Preferably, the traditional Chinese medicine additive comprises the following raw materials in parts by weight: 12 parts of cortex mori radicis, 4 parts of orange peel, 2 parts of bulbus fritillariae cirrhosae, 4 parts of fructus trichosanthis, 4 parts of herba houttuyniae, 7 parts of radix adenophorae, 8 parts of rhizoma atractylodis macrocephalae and 2 parts of liquorice.
In a second aspect, the embodiment of the invention also provides a preparation method of the traditional Chinese medicine feed additive for preventing and treating respiratory diseases of livestock and poultry, the raw materials are cleaned and dried, and then are respectively crushed to the particle size of less than 0.18mm, and the raw materials are weighed according to the weight part ratio and are mixed to obtain the traditional Chinese medicine feed additive.
The preparation method is simple and convenient to operate, and can be used for small-batch production and large-scale production.
In a third aspect, the embodiment of the invention also provides a feed for preventing and treating respiratory diseases of livestock and poultry, and the feed contains the traditional Chinese medicine feed additive.
In a fourth aspect, the embodiment of the invention also provides a preparation method of the feed for preventing and treating respiratory diseases of livestock and poultry, the traditional Chinese medicine feed additive is mixed with other raw materials to prepare the feed, and the mass content of the traditional Chinese medicine feed additive in the feed is 3-6.5 per mill. Other raw materials in the feed can be selected according to breeding requirements by referring to raw materials used in feeds such as complete feed, energy feed, protein feed, mineral supplement and the like, such as soybean meal, grains, grease, meat and bone meal and the like, and the traditional Chinese medicine feed additive can also be directly mixed with the complete feed, the energy feed, the protein feed, the mineral supplement and the like.
Preferably, when the feed is used for preventing respiratory diseases of livestock and poultry, the mass content of the traditional Chinese medicine feed additive in the feed is 3-3.2 per mill.
Preferably, when the feed is used for treating respiratory diseases of livestock and poultry, the mass content of the traditional Chinese medicine feed additive in the feed is 6-6.5 per thousand.
Preferably, the other raw materials include soybean meal, grains, grease and meat and bone meal.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail with reference to the following embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
Example 1
The embodiment of the invention provides a traditional Chinese medicine feed additive for preventing and treating respiratory system diseases of livestock and poultry, which comprises the following raw materials: 12g of cortex mori radicis, 4g of orange peel, 2g of bulbus fritillariae cirrhosae, 4g of fructus trichosanthis, 4g of herba houttuyniae, 7g of radix adenophorae, 8g of rhizoma atractylodis macrocephalae and 2g of liquorice.
The preparation method of the traditional Chinese medicine feed additive comprises the following steps: cleaning Atractylodis rhizoma, cortex Mori, pericarpium Citri Tangerinae, herba Houttuyniae, Glycyrrhrizae radix, Bulbus Fritillariae Cirrhosae, radix Adenophorae and fructus Trichosanthis respectively, oven drying, pulverizing respectively, sieving with 80 mesh sieve, weighing the pulverized raw materials according to the above ratio, and mixing.
Example 2
The embodiment of the invention provides a traditional Chinese medicine feed additive for preventing and treating respiratory system diseases of livestock and poultry, which comprises the following raw materials: 11g of cortex mori radicis, 3.5g of orange peel, 1.5g of bulbus fritillariae cirrhosae, 3.5g of fructus trichosanthis, 3.5g of houttuynia cordata, 6g of radix adenophorae, 7g of rhizoma atractylodis macrocephalae and 1.5g of liquorice.
The preparation method of the traditional Chinese medicine feed additive is the same as that of example 1.
Example 3
The embodiment of the invention provides a traditional Chinese medicine feed additive for preventing and treating respiratory system diseases of livestock and poultry, which comprises the following raw materials: 13g of cortex mori radicis, 4.5g of orange peel, 2.5g of bulbus fritillariae cirrhosae, 4.5g of fructus trichosanthis, 4.5g of herba houttuyniae, 8g of radix adenophorae, 9g of rhizoma atractylodis macrocephalae and 2.5g of liquorice.
The preparation method of the traditional Chinese medicine feed additive is the same as that of example 1.
Example 4
The embodiment of the invention provides a traditional Chinese medicine feed additive for preventing and treating respiratory system diseases of livestock and poultry, which comprises the following raw materials: 10g of cortex mori radicis, 3g of orange peel, 1g of bulbus fritillariae cirrhosae, 3g of fructus trichosanthis, 3g of herba houttuyniae, 5g of radix adenophorae, 5g of rhizoma atractylodis macrocephalae and 1g of liquorice.
The preparation method of the traditional Chinese medicine feed additive is the same as that of example 1.
Example 5
The embodiment of the invention provides a traditional Chinese medicine feed additive for preventing and treating respiratory system diseases of livestock and poultry, which comprises the following raw materials: 15g of cortex mori radicis, 5g of orange peel, 3g of bulbus fritillariae cirrhosae, 5g of fructus trichosanthis, 5g of herba houttuyniae, 10g of radix adenophorae, 10g of rhizoma atractylodis macrocephalae and 3g of liquorice.
The preparation method of the traditional Chinese medicine feed additive is the same as that of example 1.
Example 6
The embodiment of the invention provides a pig feed for preventing respiratory diseases of pigs, which comprises the traditional Chinese medicine feed additive obtained in the embodiment 1 and a complete pig feed, wherein the content of the traditional Chinese medicine feed additive is 3.12wt per thousand.
Example 7
The embodiment of the invention provides a chicken feed for preventing respiratory system diseases of chickens, which comprises the traditional Chinese medicine feed additive obtained in the embodiment 1 and a complete chicken feed, wherein the content of the traditional Chinese medicine feed additive is 3.12wt per mill.
Example 8
The embodiment of the invention provides a pig feed for treating respiratory diseases of pigs, which comprises the traditional Chinese medicine feed additive obtained in the embodiment 1 and a complete pig feed, wherein the content of the traditional Chinese medicine feed additive is 6.25wt per thousand.
Example 9
The embodiment of the invention provides a chicken feed for preventing respiratory system diseases of chickens, which comprises the traditional Chinese medicine feed additive obtained in the embodiment 1 and a complete chicken feed, wherein the content of the traditional Chinese medicine feed additive is 6.25wt per thousand.
Comparative example 1
The comparative example provides a traditional Chinese medicine feed additive for preventing and treating respiratory diseases of livestock and poultry, based on example 1, the cortex mori radicis is replaced by rhizoma phragmitis similar to the property and the effect of the cortex mori radicis, and the traditional Chinese medicine feed additive specifically comprises the following raw materials: 12g of reed rhizome, 4g of orange peel, 2g of bulbus fritillariae cirrhosae, 4g of snakegourd fruit, 4g of houttuynia cordata, 7g of adenophora stricta, 8g of bighead atractylodes rhizome and 2g of liquorice.
The preparation method is the same as example 1.
Comparative example 2
The comparative example provides a traditional Chinese medicine feed additive for preventing and treating respiratory diseases of livestock and poultry, based on example 1, the bulbus fritillariae cirrhosae is replaced by loquat with similar drug property and drug effect, and the traditional Chinese medicine feed additive specifically comprises the following raw materials: 12g of cortex mori radicis, 4g of orange peel, 2g of loquat, 4g of snakegourd fruit, 4g of houttuynia cordata, 7g of adenophora stricta, 8g of bighead atractylodes rhizome and 2g of liquorice.
The preparation method is the same as example 1.
Comparative example 3
The comparative example provides a traditional Chinese medicine feed additive for preventing and treating respiratory diseases of livestock and poultry, based on example 1, the houttuynia cordata is replaced by the plantain herb with similar drug property and drug effect, and the traditional Chinese medicine feed additive specifically comprises the following raw materials: 12g of cortex mori radicis, 4g of orange peel, 2g of bulbus fritillariae cirrhosae, 4g of fructus trichosanthis, 4g of plantain herb, 7g of adenophora stricta, 8g of rhizoma atractylodis macrocephalae and 2g of liquorice.
The preparation method is the same as example 1.
Effect example 1
420 laying hens diagnosed with the cystitis are selected from a certain chicken farm in Hebei province and randomly divided into 7 groups, namely test 1-3 groups, control 1-3 groups and blank groups. Tests 1-3 groups of the Chinese medicinal feed additive disclosed in the embodiments 1-3 of the invention are added into complete chicken feed in an amount of 6.25 per mill and are freely ingested by sick chickens; the traditional Chinese medicine feed additive of comparative examples 1-3 is added into complete chicken feed in an amount of 6.25 per mill for comparison 1-3 groups, and is freely ingested by sick chickens; the blank group was always fed with complete chicken feed. The complete chicken feed formula used in each group is the same. The animals were continuously fed for 5 days, and the cure rate of balloontis, mortality rate and total egg production per chicken averaged over 5 days were recorded for each group on day 6, and the results are shown in table 1.
TABLE 1 healing and egg laying of sick chickens
Figure BDA0002611995480000061
Note: relative to blank P < 0.05.
The experimental results show that the cure rate and the egg yield of the test group and the control group are both obviously higher than those of the blank group, the death rate is obviously lower than that of the blank group, and the cure rate and the egg yield of the test group are higher and the death rate is lower. The traditional Chinese medicine feed additive provided by the invention can effectively cure the chicken airsacculitis, improve the health level of the chicken and enable the laying rate of the chicken to be higher.
Effect example 2
420 uninfected healthy laying hens are selected in a certain chicken farm with air sacculitis in Hebei province and are randomly divided into 7 groups, namely test 1-3 groups, control 1-3 groups and blank groups. Tests 1-3 groups of the traditional Chinese medicine feed additive disclosed in the embodiments 1-3 of the invention are added into a complete chicken feed in an addition amount of 3.12 per mill and are freely ingested by chickens; the traditional Chinese medicine feed additive of comparative examples 1-3 is added into a complete chicken feed by 3.12 per mill of addition amount in comparison groups 1-3, and the feed can be freely ingested by chickens; the blank group was always fed with complete chicken feed. The complete chicken feed formula used in each group is the same. The animals were continuously fed for 5 days, and the prevalence of air pocket inflammation, mortality and total egg production per chicken averaged over 5 days were recorded for each group on day 6, and the results are shown in Table 2.
TABLE 2 infection and egg laying of healthy chickens
Figure BDA0002611995480000071
Note: relative to blank P < 0.05.
According to the experimental results, the morbidity and mortality of the test group and the control group are obviously lower than those of the blank group, the egg yield is obviously higher than that of the blank group, the morbidity and mortality of the test group are lower, and the egg yield is higher. The traditional Chinese medicine feed additive provided by the invention can effectively prevent chicken ballonfitis, and can improve the health level of chicken, so that the laying rate of the chicken is higher.
Effect example 3
Fattening pigs suffering from asthma and cough and weaned pigs with 140 heads respectively are selected from a certain pig farm in Hebei province, and the male and female pigs are respectively divided into 7 groups at random, namely, test 1-3 groups, control 1-3 groups and blank groups. Tests 1-3 groups of the traditional Chinese medicine feed additive disclosed in the embodiments 1-3 of the invention are added into fattening feed and weaned pig feed in an addition amount of 6.25 per mill, and are freely ingested by pigs; the traditional Chinese medicine feed additive of comparative examples 1-3 is added into fattening feed and weaned pig feed in an addition amount of 6.25 per mill for comparison 1-3 groups, and is freely ingested by pigs; the blank group was always fed with fattening feed and weaned piglets feed. The fattening feed and the weaned piglet feed used in each group have the same formula. The pigs were continuously fed for 7 days, and the asthma, cough cure, mortality and feed-meat ratio of the fattening pigs and piglets were recorded in the early morning of day 8, and the results are shown in tables 3 and 4.
TABLE 3 test results for various groups of fattening pigs
Figure BDA0002611995480000081
Note: relative to blank P < 0.05.
TABLE 4 test results for piglets in each group
Figure BDA0002611995480000082
Note: relative to blank P < 0.05.
The experimental results show that the groups in examples 1-3 can obviously improve the cure rate of asthma and cough of the fattening pigs and piglets, reduce the death rate, reduce the feed conversion ratio and improve the health condition of the sick pigs, and the effect is superior to that of each proportional group. The traditional Chinese medicine feed additive provided by the invention can effectively cure asthma and cough of pigs and can improve the health level of the pigs.
Effect example 4
In a certain pig farm with pigs suffering from asthma and cough in Hebei province, 140 healthy fattening pigs and weaned pigs are selected, half of the pigs are female and half of the pigs are respectively randomly divided into 7 groups, namely a test group 1-3 groups, a control group 1-3 groups and a blank group. Tests 1-3 groups of the traditional Chinese medicine feed additive disclosed in the embodiments 1-3 of the invention are added into fattening feed and weaned pig feed in an addition amount of 3.12 per mill, and are freely ingested by pigs; the traditional Chinese medicine feed additive of comparative examples 1-3 is added into fattening feed and weaned pig feed in an addition amount of 3.12 per mill for comparison 1-3 groups, and is freely ingested by pigs; the blank group was always fed with fattening feed and weaned piglets feed. The fattening feed and the weaned piglet feed used in each group have the same formula. The pigs were continuously fed for 7 days, and the asthma, cough prevalence and feed conversion ratio of the fattening pigs and piglets were recorded in the early morning of day 8, and the results are shown in tables 5 and 6.
TABLE 5 test results of various groups of fattening pigs
Figure BDA0002611995480000091
Note: relative to blank P < 0.05.
TABLE 6 test results for piglets in each group
Figure BDA0002611995480000092
Note: relative to blank P < 0.05.
The experimental results show that the groups of the examples 1 to 3 can reduce and improve the probability of asthma and cough caused by the infection of the fattening pigs and the piglets, reduce the feed conversion ratio and improve the health condition of the sick pigs, and the effect is superior to each proportional group, which shows that the traditional Chinese medicine feed additive provided by the invention can effectively prevent the asthma and the cough of the pigs and can improve the health level of the pigs.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents or improvements made within the spirit and principle of the present invention should be included in the scope of the present invention.

Claims (9)

1. The traditional Chinese medicine feed additive for preventing and treating respiratory diseases of livestock and poultry is characterized by comprising the following raw materials in parts by weight: 10-15 parts of cortex mori, 3-5 parts of orange peel, 1-3 parts of fritillaria cirrhosa, 3-5 parts of snakegourd fruit, 3-5 parts of houttuynia cordata, 5-10 parts of adenophora stricta, 5-10 parts of bighead atractylodes rhizome and 1-3 parts of liquorice.
2. The traditional Chinese medicine feed additive for preventing and treating respiratory diseases of livestock and poultry according to claim 1, which is characterized by comprising the following raw materials in parts by weight: 11-13 parts of cortex mori, 3.5-4.5 parts of orange peel, 1.5-2.5 parts of bulbus fritillariae cirrhosae, 3.5-4.5 parts of fructus trichosanthis, 3.5-4.5 parts of houttuynia cordata, 6-8 parts of adenophora stricta, 7-9 parts of rhizoma atractylodis macrocephalae and 1.5-2.5 parts of liquorice.
3. The traditional Chinese medicine feed additive for preventing and treating respiratory diseases of livestock and poultry according to claim 2, which is characterized by comprising the following raw materials in parts by weight: 12 parts of cortex mori radicis, 4 parts of orange peel, 2 parts of bulbus fritillariae cirrhosae, 4 parts of fructus trichosanthis, 4 parts of herba houttuyniae, 7 parts of radix adenophorae, 8 parts of rhizoma atractylodis macrocephalae and 2 parts of liquorice.
4. The method for preparing a traditional Chinese medicine feed additive for preventing and treating respiratory diseases of livestock and poultry according to any one of claims 1 to 3, characterized in that the raw materials are cleaned and dried, then respectively crushed to have a particle size of less than 0.18mm, and the raw materials are weighed according to the weight part ratio and mixed to obtain the traditional Chinese medicine feed additive.
5. A feed for preventing and treating respiratory diseases of livestock and poultry, which is characterized by comprising the traditional Chinese medicine feed additive for preventing and treating respiratory diseases of livestock and poultry according to any one of claims 1 to 3.
6. The preparation method of the feed for preventing and treating the respiratory system diseases of the livestock and poultry, as claimed in claim 5, is characterized in that the feed is prepared by mixing the traditional Chinese medicine feed additive with other raw materials, and the mass content of the traditional Chinese medicine feed additive in the feed is 3-6.5 per mill.
7. The preparation method of the feed for preventing and treating the respiratory diseases of the livestock and the poultry according to claim 6, wherein when the feed is used for preventing the respiratory diseases of the livestock and the poultry, the mass content of the traditional Chinese medicine feed additive in the feed is 3-3.2 per mill.
8. The preparation method of the feed for preventing and treating the respiratory diseases of the livestock and the poultry according to claim 6, wherein when the feed is used for treating the respiratory diseases of the livestock and the poultry, the mass content of the traditional Chinese medicine feed additive in the feed is 6-6.5 per mill.
9. The preparation method of the feed for preventing and treating the respiratory diseases of the livestock and the poultry according to any one of claims 6 to 8, wherein the other raw materials comprise soybean meal, grains, grease and meat and bone meal.
CN202010757299.0A 2020-07-31 2020-07-31 Traditional Chinese medicine feed additive and feed for preventing and treating respiratory system diseases of livestock and poultry and preparation method thereof Pending CN111838417A (en)

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