CN104367739A - Galactagogue for sows and preparation method of galactagogue - Google Patents

Galactagogue for sows and preparation method of galactagogue Download PDF

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Publication number
CN104367739A
CN104367739A CN201410561456.5A CN201410561456A CN104367739A CN 104367739 A CN104367739 A CN 104367739A CN 201410561456 A CN201410561456 A CN 201410561456A CN 104367739 A CN104367739 A CN 104367739A
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parts
sow
radix
galactopoietic
galactagogue
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秦甫英
卜昌超
李小广
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Zhengzhou Houyi Pharmaceutical Co Ltd
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Zhengzhou Houyi Pharmaceutical Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • A61K36/344Codonopsis
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
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    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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Abstract

The invention relates to a galactagogue for sows. The galactagogue is prepared from the following components in parts by weight: 9 to 27 parts of codonopsis pilosula, 9 to 27 parts of astragalus membranaceus, 12 to 36 parts of dandelion, 9 to 18 parts of honeysuckle, 9 to 18 parts of radix paeoniae alba, 9 to 18 parts of cortex moutan, 12 to 24 parts of rehmannia glutinosa, 9 to 21 parts of houttuynia cordata, 6 to 18 parts of tetrapanax papyriferus, 6 to 18 parts of hawthorns, 6 to 18 parts of betel nuts, 9 to 18 parts of radix aucklandiae, 9 to 21 parts of beautiful sweetgum fruit, 9 to 21 parts of angelica sinensis, 6 to 15 parts of ligusticum wallichii, 9 to 15 parts of radix bupleuri, 9 to 15 parts of semen vaccariae, 6 to 9 parts of manis pentadactyla and 6 to 9 parts of antler. Compared with the prior art, the galactagogue provided by the invention has no toxic or side effect and is capable of effectively improving the lactation performance of a lactating sow and protecting functions of the spleen and stomach of the sow to increase the lactation yield so as to favorably meet nutritional requirements of piglets in growth. As the galactagogue is used, medicines enter the body of each piglet via milk to indirectly promote the growth performance of each piglet, so that the survival rate of the piglets is increased, the disease resistance of the piglets is enhanced and the disease occurrence can be effectively controlled or prevented.

Description

One broad sow galactopoietic and preparation method thereof
Technical field
The invention belongs to veterinary Chinese medicine preparation technique field, particularly broad sow galactopoietic and preparation method thereof.
Background technology
In the developmental pattern of modern intensiveization cultivation, sow is the key link; Especially lactating sow, it is responsible for raising newborn piglet, makes the important task of overall swinery sustainable development.Along with the raising of cultural technique, the improvement of way to manage, the trophic level of swinery improves a lot, but, often occur in production that sow body condition is too obese, overnutrition, upset the phenomenon of organism endocrine, affect the lactation amount in its puerperal; Sow Postpartum constitution is weak, resists disease ability and reduces, both affected lactogenic, and also hid some dangers for the regenerative ratio in later stage.In addition, the especially antibiotic use of the various medicine of long-term abuse can bring out the drug resistance of pathogenic microorganism, the more important thing is that chemicals likely causes drug residue by being connected between lactating sow in piglet body, running counter to the aim of healthy aquaculture.
Summary of the invention
The technical problem to be solved in the present invention is sow puerperal because the disease ability that has a delicate constitution, resists reduces, affects lactogenic, also the regenerative ratio in later stage is hidden some dangers for, the abuse of medicine not only can bring out the drug resistance of pathogenic microorganism, also can cause drug residue in piglet body.For solving the problem, the invention provides broad sow galactopoietic and preparation method thereof.
The object of the invention is to realize in the following manner:
One broad sow galactopoietic, is made up of the component of following parts by weight: Radix Codonopsis 9 ~ 27 parts, the Radix Astragali 9 ~ 27 parts, Herba Taraxaci 12 ~ 36 parts, Flos Lonicerae 9 ~ 18 parts, the Radix Paeoniae Alba 9 ~ 18 parts, Cortex Moutan 9 ~ 18 parts, 12 ~ 24 parts, Radix Rehmanniae Preparata, Herba Houttuyniae 9 ~ 21 parts, Medulla Tetrapanacis 6 ~ 18 parts, Fructus Crataegi 6 ~ 18 parts, Semen Arecae 6 ~ 18 parts, the Radix Aucklandiae 9 ~ 18 parts, Fructus Liquidambaris 9 ~ 21 parts, Radix Angelicae Sinensis 9 ~ 21 parts, Rhizoma Chuanxiong 6 ~ 15 parts, Radix Bupleuri 9 ~ 15 parts, Semen Vaccariae 9 ~ 15 parts, Squama Manis 6 ~ 9 parts, 6 ~ 9 parts, Cornu Cervi.
Described sow galactopoietic is powder.
Concrete operation step is:
(1) each raw material is taken by weight;
(2) load weighted traditional Chinese medicine powder is broken into 60 orders, then superfine powder is crushed to 300 orders, mix homogeneously.
The application of described sow galactopoietic, sow galactopoietic mixes with sow feed to feed and gives sow and eat, and wherein every 100kg sow feed adds 300 ~ 700g sow galactopoietic.
The present invention selects effect of raw material to be summarized as follows:
Radix Codonopsis: property is sweet, flat; Return spleen, lung meridian, there is the effects such as enhancing body stress ability, enhancing human body immunity function, slow down aging, antiulcer, enhancing cardiovascular system; Strengthening the spleen and tonifying the lung, supplementing QI for promoting the production of body fluid; Cure mainly weakness of the spleen and stomach, anorexia and loose stool, limbs fatigue, the deficiency of the lung is breathed with cough, spontaneous perspiration of breathing hard, deficiency of both QI and blood etc.
The Radix Astragali: property is sweet, warm; Return lung, spleen channel, have and strengthen immune system, slow down aging, the effects such as antioxidation, enhancing cardiovascular system, antithrombotic, antiviral, antiinflammatory and analgesia; Benefiting qi and raising yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, promoting pus discharge and tissue regeneration strengthening; Cure mainly the card of all Qi and blood deficiencies, as diarrhea due to hypofunction of the spleen, cough due to deficiency of the lung, proctoptosis, uterine prolapse, spontaneous perspiration, night sweat, edema, arthralgia due to stagnation of blood, carbuncle difficulty is burst or is burst for a long time and do not hold back.
Herba Taraxaci: property is bitter, sweet, cold; Return liver, stomach warp, there is resisting pathogenic microbes, antiendotoxin, antitumor, anti-gastric-ulcer, function of gallbladder promoting and protect the liver, immunomodulating; The effects such as antioxidant radical; Heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation; Cure mainly acute mastitis, lung abscess, acute appendicitis, mumps, scrofula, furuncle carbuncle toxin, conjunctival congestion and swelling pain, cold, fever, cough, laryngopharynx swelling and pain, gastritis, enteritis, dysentery, hepatitis, cholecystitis, urinary tract infection etc.
Flos Lonicerae: property is sweet, cold; Attach to the lung and stomach meridians, there is the effect such as the microorganism of antigen source, antitoxin, antiinflammatory, enhancing immune system, blood fat reducing; Heat-clearing and toxic substances removing; Cure mainly affection due to external wind and heat or epidemic febrile disease, heatstroke, toxic-heat and blood stasis, carbuncle furuncle, sore throat, multi-infection disease etc.
The Radix Paeoniae Alba: property is bitter, sour, is slightly cold; Return liver, spleen channel, there is antiinflammatory, analgesia, enhancing immunologic function, resisting pathogenic microbes, CNS inhibition, anoxia enduring, protect the liver and detoxify, the effect such as antimutagenic and antitumor; Nourish blood and seek, relieving spasm to stop pain, yin fluid astringing suppressing the hyperactive liver; Cure mainly blood deficiency cold and heat, epigastric pain, hypochondriac pain, limb spasm pain, dysmenorrhea, menoxenia, metrorrhagia, spontaneous perspiration, night sweat, dysentery is had loose bowels, and has a headache dizzy.
Cortex Moutan: bitter in the mouth, pungent, cold nature, GUIXIN, liver, kidney channel, have clearing away heat and cooling blood, effect of blood circulation promoting and blood stasis dispelling, and for maculae caused by violent heat pathogen, hematemesis and epistaxis, night fever abating at dawn, lossless hectic fever due to YIN-deficiency, amenorrhea dysmenorrhea, carbuncle sore tumefacting virus, falls and flutter the pain of injury.
Radix Rehmanniae Preparata: sweet in the mouth, slightly warm in nature.Return liver, kidney channel, there is YIN nourishing effect of enriching blood, for blood deficiency and yellow complexion, dizzy, palpitation and insomnia, menoxenia, the diseases such as metrorrhagia.
Herba Houttuyniae: property is pungent, is slightly cold; Return lung, bladder, large intestine channel, there is antibacterial, antiviral, immunostimulant, diuresis; Heat-clearing and toxic substances removing, removing pus and relieving carbuncle, inducing diuresis for treating stranguria syndrome; Cure mainly lung abscess vomiting pus, lung-heat cough with asthma.
Medulla Tetrapanacis: sweet in the mouth, light, cold nature, attaches to the lung and stomach meridians, and has clearing away heat and promoting diuresis, effect of ventilation stimulating milk secretion, for hygropyrexia dark coloured urine, the puckery pain of gonorrhea, edema oliguria, agalactia.
Fructus Crataegi: property is sour, sweet, tepor; Return spleen, stomach, Liver Channel, there is the effects such as digestion promoting, blood pressure lowering, blood fat reducing, antioxidation; Promoting digestion and invigorating the stomach, circulation of qi promoting scattered silt; Cure mainly eating accumulation, abdominal distention, dysentery etc.
Semen Arecae: property is bitter, pungent, temperature; Return stomach, large intestine channel, expelling intestinal worms and removing food stagnancy, therapeutic method to keep the adverse QI flowing downwards row water, preventing the attack (or recurrence) of malaria; Cure mainly malnutrition due to parasitic infestation, dyspepsia, abdominal distention, after dysentery heavily etc.
The Radix Aucklandiae: acrid in the mouth, hardship, warm in nature, return spleen, stomach, large intestine, three burnt, gallbladder meridians, there are promoting the circulation of QI to relieve pain, effect of strengthening the spleen to promote digestion.For breast gastral cavity distending pain, heavy after dysentery, food stagnation does not disappear, anorexia.The real intestinal antidiarrheal of Radix Aucklandiae (roasted).For stomachache of having loose bowels.
Fructus Liquidambaris: bitter in the mouth, property is put down, and returns liver, kidney channel, has dispelling, collateral-activating, effect that diuretic stimulates the menstrual flow.For arthralgia, numbness contracture, edema distension, the few amenorrhea of breast.
Radix Angelicae Sinensis: nature and flavor Gan Xinwen, returns liver, the heart, spleen channel; There is blood-supplementing blood-nourishing, promoting blood circulation and stopping pain, effect of relaxing bowel.This product all has potentiation to non-specific and specific immune function, can significantly improve mouse monokaryon cytophagy, to caused by cyclophosphamide immune suppression function tool antagonistic action; The non-dialysis part of Radix Angelicae Sinensis hot water extract is that the generation of polyclone B cell activator antagonist can play strong adjuvant effect, and antibody forming cell's number and antibody titer can be made apparently higher than control animals.Radix Angelicae Sinensis in vivo, externally all can activate diversity mice bone-marrow-derived lymphocyte, directly can also activate and participate in antibody response I and arrest T lymphocyte, have very strong immunological enhancement, also to the generation of IL-2, there is obvious potentiation.
Rhizoma Chuanxiong: acrid in the mouth, warm in nature, return liver, gallbladder, pericardium channel, there is blood-activating and qi-promoting, effect of wind-expelling pain-stopping.For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen is suffered from abdominal pain, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.
Radix Bupleuri: evacuate and bring down a fever, soothing liver-QI, yang invigorating.Radix Bupleuri can be adjusted and reach irritability and dispersing the stagnated live-QI to relieve the stagnation of QI.
Semen Vaccariae: property is bitter is flat; Return liver, stomach warp, promoting blood circulation to restore menstrual flow, stimulating milk secretion eliminating carbuncle; Cure mainly abdominal pain during menstruation, amenorrhea, galactostasis, acute mastitis, carbuncle.
Squama Manis: salty, is slightly cold, and returns liver, stomach warp, is mainly used in stimulating milk secretion of stimulating the menstrual flow, detumescence and apocenosis, expel wind to dredge collateral, for Jing Bi WEIJIA, and galactostasis, carbuncle sore tumefacting virus, arthralgia, numbness contracture.
Cornu Cervi: salty, temperature, returns liver, kidney channel, has the kidney warming sun, bone and muscle strengthening, effect of promoting the circulation of blood detumescence, and for impotence and seminal emission, spinal column cold type of pain, carbuncle of yin nature skin infection, acute mastitis is from the beginning of, swelling and pain due to blood stasis.
The Radix Astragali, Radix Codonopsis air making-up and spleen enlivening in side, to match blood yiqi with Radix Rehmanniae Preparata, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Paeoniae Alba SIWU TANG, and the holy more Tang Zhiyi of residence is monarch drug altogether, tonification milk the source of vital function; Raw areca, Fructus Crataegi spleen invigorating lactogenesis, Radix Aucklandiae stomach invigorating regulating QI are minister, assist monarch drug benefiting vital QI and blood; Cornu Cervi Degelatinatum benefiting essence-blood, Radix Bupleuri liver-smoothing, qi-regulating, Squama Manis, Semen Vaccariae, Medulla Tetrapanacis, Fructus Liquidambaris, Radix Rhapontici are invigorated blood circulation, dredging collateral, stimulating milk secretion; Herba Houttuyniae, Flos Lonicerae, Herba Taraxaci, Cortex Moutan heat-clearing and toxic substances removing are adjuvant altogether.
Relative to prior art, the invention provides broad sow galactopoietic and preparation method thereof, have no side effect, can improve the milk performance of nursing sow effectively in advance, the spleen and stomach function of protection sow makes lactation amount increase, and better meets the nutritional requirement of piglet growth; Medicine enters through milk the growth performance indirectly promoting piglet in piglet body, improves the survival rate of piglet, strengthens the resistance against diseases of piglet, can effectively control or prophylactic generation.
Detailed description of the invention
Embodiment 1:
The sow galactopoietic of the present embodiment, is made up of the component of following parts by weight: Radix Codonopsis 9 ~ 27 parts, the Radix Astragali 9 ~ 27 parts, Herba Taraxaci 12 ~ 36 parts, Flos Lonicerae 9 ~ 18 parts, the Radix Paeoniae Alba 9 ~ 18 parts, Cortex Moutan 9 ~ 18 parts, 12 ~ 24 parts, Radix Rehmanniae Preparata, Herba Houttuyniae 9 ~ 21 parts, Medulla Tetrapanacis 6 ~ 18 parts, Fructus Crataegi 6 ~ 18 parts, Semen Arecae 6 ~ 18 parts, the Radix Aucklandiae 9 ~ 18 parts, Fructus Liquidambaris 9 ~ 21 parts, Radix Angelicae Sinensis 9 ~ 21 parts, Rhizoma Chuanxiong 6 ~ 15 parts, Radix Bupleuri 9 ~ 15 parts, Semen Vaccariae 9 ~ 15 parts, Squama Manis 6 ~ 9 parts, 6 ~ 9 parts, Cornu Cervi.
Concrete operation step:
(1) various crude drug is taken by described parts by weight;
(2) load weighted traditional Chinese medicine powder is broken into 60 orders, then superfine powder is crushed to 300 orders, mix homogeneously.
Sow galactopoietic mixes with sow feed to feed and gives sow and eat, and wherein every 100kg sow feed adds 300 ~ 700g sow galactopoietic.
Embodiment 2:
The sow galactopoietic of the present embodiment, is made up of the component of following parts by weight: Radix Codonopsis 90g, Radix Astragali 90g, Herba Taraxaci 120g, Flos Lonicerae 90g, Radix Paeoniae Alba 90g, Cortex Moutan 90g, Radix Rehmanniae Preparata 120g, Herba Houttuyniae 90g, Medulla Tetrapanacis 60g, Fructus Crataegi 60g, Semen Arecae 60g, Radix Aucklandiae 90g, Fructus Liquidambaris 90g, Radix Angelicae Sinensis 90g, Rhizoma Chuanxiong 60g, Radix Bupleuri 90g, Semen Vaccariae 90g, Squama Manis 60g, Cornu Cervi 60g.
The preparation method of above-mentioned Chinese medicine is undertaken by embodiment 1.
Sow galactopoietic mixes with sow feed to feed and gives sow and eat, and wherein every 100kg sow feed adds 300g sow galactopoietic.
Embodiment 3:
The sow galactopoietic of the present embodiment, is made up of the component of following parts by weight: Radix Codonopsis 150g, Radix Astragali 120g, Herba Taraxaci 300g, Flos Lonicerae 120g, Radix Paeoniae Alba 120g, Cortex Moutan 120g, Radix Rehmanniae Preparata 180g, Herba Houttuyniae 180g, Medulla Tetrapanacis 120g, Fructus Crataegi 150g, Semen Arecae 160g, Radix Aucklandiae 160g, Fructus Liquidambaris 150g, Radix Angelicae Sinensis 130g, Rhizoma Chuanxiong 80g, Radix Bupleuri 110g, Semen Vaccariae 100g, Squama Manis 70g, Cornu Cervi 70g.
The preparation method of above-mentioned Chinese medicine is undertaken by embodiment 1.
Sow galactopoietic mixes with sow feed to feed and gives sow and eat, and wherein every 100kg sow feed adds 400g sow galactopoietic.
Embodiment 4:
The sow galactopoietic of the present embodiment, is made up of the component of following parts by weight: Radix Codonopsis 200g, Radix Astragali 180g, Herba Taraxaci 250g, Flos Lonicerae 150g, Radix Paeoniae Alba 150g, Cortex Moutan 150g, Radix Rehmanniae Preparata 200g, Herba Houttuyniae 150g, Medulla Tetrapanacis 90g, Fructus Crataegi 120g, Semen Arecae 120g, Radix Aucklandiae 120g, Fructus Liquidambaris 120g, Radix Angelicae Sinensis 150g, Rhizoma Chuanxiong 100g, Radix Bupleuri 130g, Semen Vaccariae 120g, Squama Manis 60g, Cornu Cervi 80g.
The preparation method of above-mentioned Chinese medicine is undertaken by embodiment 1.
Sow galactopoietic mixes with sow feed to feed and gives sow and eat, and wherein every 100kg sow feed adds 500g sow galactopoietic.
Embodiment 5:
The sow galactopoietic of the present embodiment, is made up of the component of following parts by weight: Radix Codonopsis 240g, Radix Astragali 210g, Herba Taraxaci 180g, Flos Lonicerae 160g, Radix Paeoniae Alba 100g, Cortex Moutan 100g, Radix Rehmanniae Preparata 150g, Herba Houttuyniae 120g, Medulla Tetrapanacis 150g, Fructus Crataegi 90g, Semen Arecae 80g, Radix Aucklandiae 140g, Fructus Liquidambaris 180g, Radix Angelicae Sinensis 180g, Rhizoma Chuanxiong 120g, Radix Bupleuri 120g, Semen Vaccariae 140g, Squama Manis 80g, Cornu Cervi 90g.
The preparation method of above-mentioned Chinese medicine is undertaken by embodiment 1.
Sow galactopoietic mixes with sow feed to feed and gives sow and eat, and wherein every 100kg sow feed adds 600g sow galactopoietic.
Embodiment 6:
The sow galactopoietic of the present embodiment, is made up of the component of following parts by weight: Radix Codonopsis 270g, Radix Astragali 270g, Herba Taraxaci 360g, Flos Lonicerae 180g, Radix Paeoniae Alba 180g, Cortex Moutan 180g, Radix Rehmanniae Preparata 240g, Herba Houttuyniae 210g, Medulla Tetrapanacis 180g, Fructus Crataegi 180g, Semen Arecae 180g, Radix Aucklandiae 180g, Fructus Liquidambaris 210g, Radix Angelicae Sinensis 210g, Rhizoma Chuanxiong 150g, Radix Bupleuri 150g, Semen Vaccariae 150g, Squama Manis 90g, Cornu Cervi 90g.
The preparation method of above-mentioned Chinese medicine is undertaken by embodiment 1.
Sow galactopoietic mixes with sow feed to feed and gives sow and eat, and wherein every 100kg sow feed adds 700g sow galactopoietic.
Embodiment 7:
The sow galactopoietic of the present embodiment, is made up of the component of following parts by weight: Radix Codonopsis 100, 110, 120, 130, 140, 160, 170, 180, 190, 210, 220, 230, 250, 260g, the Radix Astragali 100, 110, 130, 140, 150, 160, 170, 190, 200, 220, 230, 240, 250, 260g, Herba Taraxaci 130, 140, 150, 160, 170, 200, 220, 240, 260, 280, 320, 340g, Flos Lonicerae 100, 110, 130, 140, 170g, the Radix Paeoniae Alba 110, 130, 140, 160, 170g, Cortex Moutan 110, 130, 140, 160, 170g, Radix Rehmanniae Preparata 130, 140, 160, 170, 190, 210, 220, 230g, Herba Houttuyniae 100, 110, 130, 140, 160, 170, 190, 200g, Medulla Tetrapanacis 70, 80, 100, 110, 130, 140, 160, 170g, Fructus Crataegi 70, 80, 100, 110, 130, 140, 160, 170g, Semen Arecae 70, 90, 100, 110, 130, 140, 150, 170g, the Radix Aucklandiae 100, 110, 130, 150, 170g, Fructus Liquidambaris 100, 110, 130, 140, 160, 170, 190, 200g, Radix Angelicae Sinensis 100, 110, 120, 140, 160, 170, 190, 200g, Rhizoma Chuanxiong 70, 90, 110, 130, 140g, Radix Bupleuri 95, 100, 105, 115, 125, 135, 140, 145g, Semen Vaccariae 95, 105, 110, 115, 125, 130, 135, 145g, Squama Manis 65, 68, 75, 78, 85, 88g, Cornu Cervi 65, 68, 75, 78, 85, 88g.
The preparation method of above-mentioned Chinese medicine is undertaken by embodiment 1.
Sow galactopoietic mixes with sow feed to feed and gives sow and eat, wherein every 100kg sow feed add 350,450,550,650g sow galactopoietic.
Clinical experimental study materials and methods
1.1 experimental animal
Select 40 physically fit, well-developed Suprapubic arch sling on Zhengzhou Hou Yi group 8,000 pig farm, parity basically identical (3-4 tire), weight differences is little, and produce piglet number of living close, birth weight is close.Every nest ensures the young 10-11 head of band, and farrowing, more than 11, will be greater than 1.8Kg and be less than 1Kg, parasiticly gives other sow, guarantees experimental group and matched group, at the relative equality of piglet birth weight, every nest band piglet.Feed in same environment, other aspects are substantially close.Unified number is carried out to 40 sows, is divided into 4 groups at random, often organize 10, be respectively: Basal control group, embodiment 1 group, embodiment 2 groups, embodiment 3 groups.
1.2 trial drug
By powder prepared by embodiment 2,3,4.
The basal diet formula of 1.3 nursing sow and component content
With reference to Animal nutrition standard design basal diet formula, according to production sow nutritional need accurate formulation, primary raw material has Semen Maydis, bean cake, Testa Tritici and fish flour.Basal diet is specifically in table 1.
Table 1 basal diet and component content
Daily ration forms Proportioning/% Major Nutrient index Trophic level
Semen Maydis 50.00 DE/MJ.Kg 13.30
Bean cake 18.50 CF 4.60
Testa Tritici 28.00 CP 16.50
Fish flour 2.00 Ca 1.25
Sal 0.50 P 0.65
Compound additive 1.50 Lys+Met+Cys 1.36
Add up to 100
1.4 EXPERIMENTAL DESIGN
This test adopts the design of completely random group experiment, is divided into four groups, matched group sow feeding basal diet, and embodiment 1 group, embodiment 2 groups, embodiment 3 groups of sow feeding basal diets add galactopoietic, specifically in table 2.
Table 2 EXPERIMENTAL DESIGN
1.5 feeding and management
Before on-test, delivery room is cleaned, sterilizes, carry out the antenatal preparation of sow.After test pig grouping, sow starts test for antenatal 3 days.Test group is the same with matched group, and sow uses same basal diet; Embodiment group adds galactopoietic; Until 21 days puerperal of sow.Other schemes are carried out according to pig farm Routine Management and immune programme for children.
This test was carried out on Zhengzhou 8,000 Hou Yi group pig farm from March 5th, 2013.Test sow material reducing in antenatal 3 days, with the material reducing of descending mode.Adopt incremental manner feeding puerperal, the 1st day puerperal, about the 1kg that feeds, increased later gradually, was added to about 4kg by the 7th day, after stable, by nursing sow amount feed.While reinforced to sow, answer in liberal supply clean drinking water, to increase lactation amount and nursing time a day.
Sow promotes development of breast by manual massage's breast puerperal, and main time is antenatal 2 weeks and 1 week puerperal.Antenatal, each 1 time of morning every day, evening, rub pig breast with have gentle hands, continue 20s at every turn; In puerperal, massaging breasts deposited by the warm towel temperature of about 45 DEG C, at each 1 time of every day at upper and lower noon, each 10s, can promote sow blood circulation of breast, increases milk yield., also can squeeze by each breast at massaging breasts simultaneously, observe and whether have papillary foramina to block, if there is available hands suitably to extrude nipple, breast plug is extruded, to realize unobstructed lactogenic.Carry out farrowing house environmental health, ground requires clean, when ensureing the temperature in delivery room, ventilating and wanting good.Humidity in delivery room will be suitable for, not too high or too low; Noise will have been avoided inside and outside delivery room.Carry out the work of delivering a child of suckling pig, comprise removing amniotic membrane amniotic fluid, cut off umbilical cord, cut overbit, cut tail, practise midwifery, record etc.Timely supply colostrum and fixing nipple, carry out heat insulation work.
1.6 test determination projects
Test in units of sows by four groups, record the product subnumber often organizing every nest respectively, birth whose body weight, statistics often organizes litter weight, the whose body weight after wean in 21 days, adds up the rear litter weight of wean in 21 days, and statistical average daily gain.Observe piglet ordinary circumstance and sick, diarrhoea and feces exception, dead and wounded quantity and reason.
Average daily gain: respectively at piglet be born that day and the 21st day morning 9 piglets on an empty stomach, weigh by head, with 21 days averages of the difference of be born nest body weight and 21 days wean nest body weight for average daily gain.
Diarrhea rate: diarrhea rate (%)=diarrhoea head number summation/piglet head number × 100%.
Survival rate: survive number/litter size after wean in 21 days.
2 test results and analysis
The data of three groups of test data sheets, observation are in table 3.
Table 3 test data sheet
Group Matched group Embodiment 1 group Embodiment 2 groups Embodiment 3 groups
Sow head number/head 10 10 10 10
Test period/d 21 21 21 21
Piglet number/head 104 105 105 106
Birth weight/kg 1.30±0.32 1.30±0.33 1.29±0.33 1.27±0.34
Born weight/kg 135.28±0.67 136.50±0.68 134.45±0.67 134.62±0.67
Diarrhoea/head 20 11 9 10
21 ages in days survive number/head 98 102 103 104
21 age in days body weight/kg 5.6±0.45 6.8±0.44 6.7±0.42 6.8±0.42
21 age in days litter weight/kg 548.80±1.14 693.60±1.13 690.10±1.12 707.10±1.10
Note: in process of the test, indivedual piglet is sick by treatment, survives.
2.1 galactopoietics are on the impact of suckling pig growth performance
From table 4, embodiment 1 group, embodiment 2 groups, embodiment 3 groups are close with litter weight during birth with matched group litter size, and difference is not significantly (P>0.05).After 21 ages in days, embodiment 1 group, embodiment 2 groups, embodiment 3 groups compare with matched group, improve 26.57%, 25.75%, 28.84% respectively, and difference extremely significantly (P<0.01); Embodiment 1 group, embodiment 2 groups, embodiment 3 groups compare, and difference is not significantly (P>0.05).
Table 4 21 age in days postfovea anharmonic ratio comparatively
Group Nest number/head Piglet number/head Born weight/kg 21 age in days litter weight/kg
Matched group 10 104 a 135.28±0.67 548.80±1.14 a
Embodiment 1 group 10 105 a 136.50±0.68 693.60±1.13 b
Embodiment 2 groups 10 105 a 134.45±0.67 690.10±1.12 b
Embodiment 3 groups 10 106 a 134.62±0.67 707.10±1.10 b
Note: represent difference not significantly (P>0.05) with the identical person of column data shoulder note lower case a or b; Lower case ab person is had to represent significant difference (P<0.05); Lower case difference person represents that difference extremely significantly (P<0.01), lower same.
2.2 galactopoietics are on the impact of suckling pig average daily gain
From table 2 and table 5, four groups of test birth weights are close, and difference is not significantly (P>0.05).21 age in days individual weights, embodiment 1 group, embodiment 2 groups, embodiment 3 groups compare with matched group, and difference is extremely significantly (P<0.01); Embodiment 1 group compares with embodiment 2 groups, and difference is not significantly (P>0.05).Embodiment 1 group, embodiment 2 groups, embodiment 3 groups of average daily gains improve 27.80%, 25.85%, 28.29% than matched group respectively.
The average daily gain of table 5 suckling pig
Group Test period/d Birth weight/kg 21 age in days body weight/kg Average daily gain/kg
Matched group 21 1.30±0.32 a 5.6±0.45 a 0.205±0.03 a
Embodiment 1 group 21 1.30±0.33 a 6.8±0.44 b 0.262±0.05 b
Embodiment 2 groups 21 1.29±0.33 a 6.7±0.42 b 0.258±0.06 b
Embodiment 3 groups 21 1.27±0.34 a 6.8±0.42 b 0.263±0.06 b
2.3 galactopoietics are on the diarrhoea of suckling pig and dead impact
From table 3 and table 6, embodiment 1 group, embodiment 2 groups, embodiment 3 groups compare with matched group, piglet diarrhea and death all extremely significantly (P<0.01) diarrhea rate and mortality rate all reduce, mortality rate reduces 59.16%, 67.07%, 67.07% respectively, diarrhea rate reduces 48.00%, 50.43%, 50.55 respectively, and embodiment 1 group, embodiment 2 groups, embodiment 3 groups of differences are not significantly (P>0.05).
Table 6 is group suckling pig diarrhea rate and mortality rate respectively
Group Farrowing/head Death/head Diarrhoea/head Mortality rate/% Diarrhea rate/%
Matched group 104 6 20 5.77 19.23
Embodiment 1 group 105 3 11 2.86 10.48
Embodiment 2 groups 105 2 9 1.90 8.57
Embodiment 3 groups 106 2 10 1.90 9.51
Note: have indivedual several first-born disease in process of the test, survived by certain treatment.
3 discuss
Chinese veterinarian's theory is thought " the lower baby of breast has disease, must recuperate under medical treatment its mother, and the sick son of mother is sick, female An Zian ", illustrates that young stock falls ill and its mother has certain relation.Adopt pure Chinese medicine ingredients, have no side effect; Have benefiting qi and nourishing blood, dysmenorrhea row breast, the effects such as stomach invigorating, heat-clearing and toxic substances removing, raising immunity of organisms, can effectively suppress or kill pathogen; The spleen and stomach function of protection sow, to reach the milk performance improving nursing sow, indirectly promotes the growth performance of piglet, improves the survival rate of piglet, strengthens the resistance against diseases of piglet, can effectively control or prophylactic generation.Medicine enters in piglet body through milk, also can improve the digestive function of piglet, promotes Piglet Development, improves fertility performance and feed conversion rate; Meet the requirement that intensive industrialized piggery group support group prevents and produces pollution-free food.

Claims (4)

1. a broad sow galactopoietic, is characterized in that: be made up of the component of following parts by weight: Radix Codonopsis 9 ~ 27 parts, the Radix Astragali 9 ~ 27 parts, Herba Taraxaci 12 ~ 36 parts, Flos Lonicerae 9 ~ 18 parts, the Radix Paeoniae Alba 9 ~ 18 parts, Cortex Moutan 9 ~ 18 parts, 12 ~ 24 parts, Radix Rehmanniae Preparata, Herba Houttuyniae 9 ~ 21 parts, Medulla Tetrapanacis 6 ~ 18 parts, Fructus Crataegi 6 ~ 18 parts, Semen Arecae 6 ~ 18 parts, the Radix Aucklandiae 9 ~ 18 parts, Fructus Liquidambaris 9 ~ 21 parts, Radix Angelicae Sinensis 9 ~ 21 parts, Rhizoma Chuanxiong 6 ~ 15 parts, Radix Bupleuri 9 ~ 15 parts, Semen Vaccariae 9 ~ 15 parts, Squama Manis 6 ~ 9 parts, 6 ~ 9 parts, Cornu Cervi.
2. sow galactopoietic according to claim 1, is characterized in that: described sow galactopoietic is powder.
3. the preparation method of sow galactopoietic according to claim 1 and 2, is characterized in that: concrete operation step is:
(1) each raw material is taken by weight;
(2) load weighted traditional Chinese medicine powder is broken into 60 orders, then superfine powder is crushed to 300 orders, mix homogeneously.
4. the application of sow galactopoietic according to claim 1 and 2, is characterized in that: sow galactopoietic mixes with sow feed to feed and gives sow and eat, and wherein every 100kg sow feed adds 300 ~ 700g sow galactopoietic.
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CN105918669A (en) * 2016-04-28 2016-09-07 青岛海之星生物科技有限公司 Additive feed for farrowing sow and preparation method thereof
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CN113142406A (en) * 2021-05-07 2021-07-23 牛铁涛 Medicated diet nutrition conditioner for improving health of sows and piglets in lactation period and preparation method and application thereof
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CN114289144A (en) * 2021-12-31 2022-04-08 福建省龙岩市华龙饲料有限公司 Feed for sows in lactation period, and production method and equipment thereof

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Publication number Priority date Publication date Assignee Title
CN105010729A (en) * 2015-08-03 2015-11-04 四川国凤中科生物科技有限公司 Preparation method of feed additive for lactating sows
CN107173574A (en) * 2016-03-13 2017-09-19 刘吴阳 One kind breaks wet nurse's pig feed additive
CN106578484A (en) * 2016-03-15 2017-04-26 河南天聚福餐饮管理有限公司 Chinese herbal medicine feed supplement for sows in suckling period
CN105918669A (en) * 2016-04-28 2016-09-07 青岛海之星生物科技有限公司 Additive feed for farrowing sow and preparation method thereof
CN106038746A (en) * 2016-06-20 2016-10-26 陆川县新洲养殖场 Method for promoting lactation of sow
CN106858100A (en) * 2017-03-02 2017-06-20 重庆开洲九鼎牧业科技开发有限公司 Agent of feed for nursing sow with lactagogue effect
CN107397061A (en) * 2017-08-10 2017-11-28 董莉 A kind of sows in lactation feed
CN109463542A (en) * 2018-11-29 2019-03-15 深圳农畉食品开发集团有限公司 A kind of sow lactagogue forage and preparation method
CN113180157A (en) * 2021-04-16 2021-07-30 哈尔滨品赫生物科技有限公司 Traditional Chinese medicine composition for improving reproductive performance of sows and active ingredients
CN113142406A (en) * 2021-05-07 2021-07-23 牛铁涛 Medicated diet nutrition conditioner for improving health of sows and piglets in lactation period and preparation method and application thereof
CN114289144A (en) * 2021-12-31 2022-04-08 福建省龙岩市华龙饲料有限公司 Feed for sows in lactation period, and production method and equipment thereof

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