CN111789190A - Traditional Chinese medicine feed additive for improving animal organism immunity, feed and preparation method - Google Patents
Traditional Chinese medicine feed additive for improving animal organism immunity, feed and preparation method Download PDFInfo
- Publication number
- CN111789190A CN111789190A CN202010758728.6A CN202010758728A CN111789190A CN 111789190 A CN111789190 A CN 111789190A CN 202010758728 A CN202010758728 A CN 202010758728A CN 111789190 A CN111789190 A CN 111789190A
- Authority
- CN
- China
- Prior art keywords
- parts
- chinese medicine
- traditional chinese
- feed additive
- immunity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 title claims abstract description 74
- 239000003674 animal food additive Substances 0.000 title claims abstract description 67
- 230000036039 immunity Effects 0.000 title claims abstract description 37
- 241001465754 Metazoa Species 0.000 title claims abstract description 30
- 238000002360 preparation method Methods 0.000 title claims abstract description 20
- 239000002994 raw material Substances 0.000 claims description 27
- 241000205585 Aquilegia canadensis Species 0.000 claims description 20
- 241000334160 Isatis Species 0.000 claims description 20
- 241000007126 Codonopsis pilosula Species 0.000 claims description 18
- 244000303040 Glycyrrhiza glabra Species 0.000 claims description 18
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 claims description 18
- 235000006533 astragalus Nutrition 0.000 claims description 17
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 claims description 17
- 235000011477 liquorice Nutrition 0.000 claims description 17
- 235000002722 Dioscorea batatas Nutrition 0.000 claims description 16
- 235000006536 Dioscorea esculenta Nutrition 0.000 claims description 16
- 240000001811 Dioscorea oppositifolia Species 0.000 claims description 16
- 235000003416 Dioscorea oppositifolia Nutrition 0.000 claims description 16
- 235000017784 Mespilus germanica Nutrition 0.000 claims description 13
- 244000182216 Mimusops elengi Species 0.000 claims description 13
- 235000000560 Mimusops elengi Nutrition 0.000 claims description 13
- 235000007837 Vangueria infausta Nutrition 0.000 claims description 13
- 241001061264 Astragalus Species 0.000 claims description 12
- 241000208688 Eucommia Species 0.000 claims description 12
- 210000004233 talus Anatomy 0.000 claims description 12
- 235000001287 Guettarda speciosa Nutrition 0.000 claims description 11
- 241000382455 Angelica sinensis Species 0.000 claims description 6
- 244000237330 gutta percha tree Species 0.000 claims description 6
- 241000045403 Astragalus propinquus Species 0.000 claims description 5
- 235000015468 Lycium chinense Nutrition 0.000 claims description 5
- 235000015459 Lycium barbarum Nutrition 0.000 claims description 4
- 235000019735 Meat-and-bone meal Nutrition 0.000 claims description 3
- 235000019764 Soybean Meal Nutrition 0.000 claims description 3
- 239000004519 grease Substances 0.000 claims description 3
- 238000002156 mixing Methods 0.000 claims description 3
- 239000002245 particle Substances 0.000 claims description 3
- 239000004455 soybean meal Substances 0.000 claims description 3
- 238000000034 method Methods 0.000 claims description 2
- 244000241838 Lycium barbarum Species 0.000 claims 2
- 240000002045 Guettarda speciosa Species 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 19
- 244000144972 livestock Species 0.000 abstract description 16
- 210000000952 spleen Anatomy 0.000 abstract description 15
- 210000003734 kidney Anatomy 0.000 abstract description 14
- 210000004185 liver Anatomy 0.000 abstract description 14
- 210000002216 heart Anatomy 0.000 abstract description 7
- 206010000210 abortion Diseases 0.000 abstract description 6
- 231100000176 abortion Toxicity 0.000 abstract description 6
- 238000005728 strengthening Methods 0.000 abstract description 6
- 230000001506 immunosuppresive effect Effects 0.000 abstract description 5
- 230000002708 enhancing effect Effects 0.000 abstract description 3
- 230000036512 infertility Effects 0.000 abstract description 3
- 230000001717 pathogenic effect Effects 0.000 abstract description 3
- 230000028327 secretion Effects 0.000 abstract description 3
- 208000002254 stillbirth Diseases 0.000 abstract description 3
- 231100000537 stillbirth Toxicity 0.000 abstract description 3
- 208000011580 syndromic disease Diseases 0.000 abstract description 3
- 231100000331 toxic Toxicity 0.000 abstract description 3
- 230000002588 toxic effect Effects 0.000 abstract description 3
- 241000756943 Codonopsis Species 0.000 abstract description 2
- 241000628997 Flos Species 0.000 abstract description 2
- 239000009636 Huang Qi Substances 0.000 abstract description 2
- 239000010231 banlangen Substances 0.000 abstract description 2
- 239000000463 material Substances 0.000 abstract description 2
- 230000013011 mating Effects 0.000 abstract description 2
- 231100000167 toxic agent Toxicity 0.000 abstract 1
- 239000003440 toxic substance Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 description 15
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 14
- 201000010099 disease Diseases 0.000 description 13
- 244000144977 poultry Species 0.000 description 13
- 235000013594 poultry meat Nutrition 0.000 description 13
- 241000287828 Gallus gallus Species 0.000 description 12
- 235000013330 chicken meat Nutrition 0.000 description 12
- 230000000052 comparative effect Effects 0.000 description 11
- 244000061520 Angelica archangelica Species 0.000 description 10
- 238000012360 testing method Methods 0.000 description 10
- 210000004369 blood Anatomy 0.000 description 9
- 239000008280 blood Substances 0.000 description 9
- 210000004072 lung Anatomy 0.000 description 8
- 239000000654 additive Substances 0.000 description 7
- 241000282887 Suidae Species 0.000 description 6
- 241000282898 Sus scrofa Species 0.000 description 6
- 241000700605 Viruses Species 0.000 description 5
- 230000000996 additive effect Effects 0.000 description 5
- 238000011084 recovery Methods 0.000 description 5
- 210000002784 stomach Anatomy 0.000 description 5
- 241000721047 Danaus plexippus Species 0.000 description 4
- 238000009395 breeding Methods 0.000 description 4
- 230000001488 breeding effect Effects 0.000 description 4
- 230000007812 deficiency Effects 0.000 description 4
- 230000035935 pregnancy Effects 0.000 description 4
- 241000894006 Bacteria Species 0.000 description 3
- 206010012735 Diarrhoea Diseases 0.000 description 3
- 244000241872 Lycium chinense Species 0.000 description 3
- 238000010521 absorption reaction Methods 0.000 description 3
- 230000036541 health Effects 0.000 description 3
- 208000015181 infectious disease Diseases 0.000 description 3
- 231100000419 toxicity Toxicity 0.000 description 3
- 230000001988 toxicity Effects 0.000 description 3
- 239000003053 toxin Substances 0.000 description 3
- 231100000765 toxin Toxicity 0.000 description 3
- 108700012359 toxins Proteins 0.000 description 3
- 241000132012 Atractylodes Species 0.000 description 2
- 206010007247 Carbuncle Diseases 0.000 description 2
- 241000123589 Dipsacus Species 0.000 description 2
- 206010062016 Immunosuppression Diseases 0.000 description 2
- 231100000678 Mycotoxin Toxicity 0.000 description 2
- 206010030113 Oedema Diseases 0.000 description 2
- 239000002671 adjuvant Substances 0.000 description 2
- 208000007502 anemia Diseases 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 230000002950 deficient Effects 0.000 description 2
- 230000029087 digestion Effects 0.000 description 2
- 235000004879 dioscorea Nutrition 0.000 description 2
- 230000000857 drug effect Effects 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 230000003203 everyday effect Effects 0.000 description 2
- 230000036737 immune function Effects 0.000 description 2
- 230000008629 immune suppression Effects 0.000 description 2
- 208000000509 infertility Diseases 0.000 description 2
- 229940029985 mineral supplement Drugs 0.000 description 2
- 235000020786 mineral supplement Nutrition 0.000 description 2
- 239000002636 mycotoxin Substances 0.000 description 2
- 230000007935 neutral effect Effects 0.000 description 2
- 230000002265 prevention Effects 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 210000004994 reproductive system Anatomy 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 229960005486 vaccine Drugs 0.000 description 2
- 210000001835 viscera Anatomy 0.000 description 2
- 238000005303 weighing Methods 0.000 description 2
- 206010000234 Abortion spontaneous Diseases 0.000 description 1
- 208000007407 African swine fever Diseases 0.000 description 1
- 208000006820 Arthralgia Diseases 0.000 description 1
- 208000027312 Bursal disease Diseases 0.000 description 1
- 241000701931 Canine parvovirus Species 0.000 description 1
- 206010007882 Cellulitis Diseases 0.000 description 1
- 241001533384 Circovirus Species 0.000 description 1
- 208000034657 Convalescence Diseases 0.000 description 1
- 206010011224 Cough Diseases 0.000 description 1
- 208000035240 Disease Resistance Diseases 0.000 description 1
- 206010059866 Drug resistance Diseases 0.000 description 1
- 206010055690 Foetal death Diseases 0.000 description 1
- 208000007212 Foot-and-Mouth Disease Diseases 0.000 description 1
- 241000710198 Foot-and-mouth disease virus Species 0.000 description 1
- 235000017443 Hedysarum boreale Nutrition 0.000 description 1
- 235000007858 Hedysarum occidentale Nutrition 0.000 description 1
- 208000002979 Influenza in Birds Diseases 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 208000004880 Polyuria Diseases 0.000 description 1
- 208000027954 Poultry disease Diseases 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- 206010044302 Tracheitis Diseases 0.000 description 1
- 208000036142 Viral infection Diseases 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- 229940107666 astragalus root Drugs 0.000 description 1
- 235000019606 astringent taste Nutrition 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 238000010923 batch production Methods 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000001186 cumulative effect Effects 0.000 description 1
- 230000002354 daily effect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 210000002249 digestive system Anatomy 0.000 description 1
- 230000006806 disease prevention Effects 0.000 description 1
- 208000032625 disorder of ear Diseases 0.000 description 1
- 230000035619 diuresis Effects 0.000 description 1
- 230000003628 erosive effect Effects 0.000 description 1
- 230000012173 estrus Effects 0.000 description 1
- 210000003754 fetus Anatomy 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 239000001947 glycyrrhiza glabra rhizome/root Substances 0.000 description 1
- 230000028993 immune response Effects 0.000 description 1
- 210000000987 immune system Anatomy 0.000 description 1
- 230000007365 immunoregulation Effects 0.000 description 1
- 230000002458 infectious effect Effects 0.000 description 1
- 231100000535 infertility Toxicity 0.000 description 1
- 206010022000 influenza Diseases 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 210000002429 large intestine Anatomy 0.000 description 1
- 238000011031 large-scale manufacturing process Methods 0.000 description 1
- 201000009837 laryngotracheitis Diseases 0.000 description 1
- 210000000265 leukocyte Anatomy 0.000 description 1
- 210000004698 lymphocyte Anatomy 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 244000000010 microbial pathogen Species 0.000 description 1
- 208000015994 miscarriage Diseases 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000036565 night sweats Effects 0.000 description 1
- 206010029410 night sweats Diseases 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 208000009305 pseudorabies Diseases 0.000 description 1
- 238000010298 pulverizing process Methods 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000001850 reproductive effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000005201 spleen development Effects 0.000 description 1
- 208000000995 spontaneous abortion Diseases 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 230000035900 sweating Effects 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 210000002435 tendon Anatomy 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 229940126680 traditional chinese medicines Drugs 0.000 description 1
- 230000009385 viral infection Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/20—Animal feeding-stuffs from material of animal origin
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/20—Animal feeding-stuffs from material of animal origin
- A23K10/26—Animal feeding-stuffs from material of animal origin from waste material, e.g. feathers, bones or skin
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
- A23K10/37—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms from waste material
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/158—Fatty acids; Fats; Products containing oils or fats
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K40/00—Shaping or working-up of animal feeding-stuffs
- A23K40/10—Shaping or working-up of animal feeding-stuffs by agglomeration; by granulation, e.g. making powders
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/70—Feeding-stuffs specially adapted for particular animals for birds
- A23K50/75—Feeding-stuffs specially adapted for particular animals for birds for poultry
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/19—Acanthaceae (Acanthus family)
- A61K36/195—Strobilanthes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
- A61K36/315—Isatis, e.g. Dyer's woad
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/344—Codonopsis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/46—Eucommiaceae (Eucommia family), e.g. hardy rubber tree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/894—Dioscoreaceae (Yam family)
- A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P60/00—Technologies relating to agriculture, livestock or agroalimentary industries
- Y02P60/80—Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
- Y02P60/87—Re-use of by-products of food processing for fodder production
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Epidemiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Food Science & Technology (AREA)
- Zoology (AREA)
- Animal Husbandry (AREA)
- Physiology (AREA)
- Molecular Biology (AREA)
- Birds (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Fodder In General (AREA)
Abstract
The invention relates to the technical field of feed additives, in particular to a traditional Chinese medicine feed additive for improving the immunity of animal organisms, a feed and a preparation method. The feed additive contains radix astragali, rhizoma Dioscoreae, radix Codonopsis, Glycyrrhrizae radix, flos Lonicerae, radix Isatidis, fructus Lycii, Eucommiae cortex and radix Angelicae sinensis, has effects of strengthening vital qi to eliminate pathogenic factor, resisting toxic substance, enhancing immunity, clearing away heat and toxic materials, tonifying heart, invigorating spleen, protecting liver and kidney, can regulate and rapidly improve livestock and fowl organism immunity in all directions, and can synergistically control and eliminate immunosuppressive syndrome caused by various reasons. The traditional Chinese medicine feed additive can also regulate the secretion of female animals in bodies, remarkably reduce the conditions of abortion, stillbirth, repeated mating sterility and the like, and can enhance the resistance of young animals.
Description
Technical Field
The invention relates to the technical field of feeds, in particular to a traditional Chinese medicine feed additive for improving the immunity of an animal organism, a feed and a preparation method.
Background
With the rapid development of the breeding industry, the problems caused by diseases in large-scale breeding are increasingly prominent, especially immunosuppressive diseases, which can cause the immune functions in livestock and poultry to be defective, the immunity to be low or even disappear, the self-protection immune barrier is lost, the disease prevention capability is extremely poor, the organism is extremely susceptible to pathogenic microorganisms, and conditional pathogenic infection is easy to occur, so that various diseases are integrated, the disease condition is complicated, the treatment difficulty is high, the administration effect is poor, the disease condition is difficult to diagnose and cure repeatedly, and even the death rate is high.
There are many factors that cause immunosuppression in livestock and poultry, such as: the unreasonable application of antibiotics can cause damage to the heart, lung, liver, spleen, kidney and the like of internal organs of livestock and poultry, so that the internal organ balance is difficult to maintain, the body resistance is rapidly reduced, and various pathogenic diseases enter the livestock and poultry while being deficient; mycotoxins and other drugs are metabolized by the liver and excreted by the kidney, and when the liver and the kidney are damaged, toxin accumulation can be caused, so that the immune system is damaged and the immune response is strongly inhibited; the body can be immune tolerant after the wrong vaccine is inoculated, and further immune suppression is formed. The livestock and poultry diseases are more and more complicated due to the reasons, and the vaccine is difficult to take effect when being used, thereby causing great economic loss to farmers.
Disclosure of Invention
Aiming at the technical problem that livestock and poultry in the prior art can generate immunosuppression, the invention provides a traditional Chinese medicine feed additive for improving the immunity of animal organisms, a feed and a preparation method thereof.
In order to achieve the purpose of the invention, the embodiment of the invention adopts the following technical scheme:
on one hand, the embodiment of the invention provides a traditional Chinese medicine feed additive for improving the immunity of animal organisms, which comprises the following raw materials in parts by weight: 10-20 parts of astragalus membranaceus, 10-20 parts of Chinese yam, 10-15 parts of codonopsis pilosula, 5-10 parts of liquorice, 5-10 parts of honeysuckle, 10-15 parts of isatis root, 10-20 parts of wolfberry, 10-15 parts of eucommia ulmoides and 10-20 parts of angelica sinensis.
According to the problems of low immune function and susceptibility to epidemic diseases of livestock and poultry under the condition of large-scale breeding, the traditional Chinese medicine formula is prepared as the feed additive through a large number of researches.
In the formula, the astragalus membranaceus is slightly warm in nature, enters lung, spleen, liver and kidney channels, benefits qi to raise yang, strengthens exterior and stops sweating, induces diuresis to alleviate edema, and can be used for treating the symptoms of qi and blood deficiency, such as spleen deficiency diarrhea, lung deficiency cough, spontaneous perspiration, night sweat, edema, blood arthralgia, carbuncle, cellulitis and non-astringency; the yam has mild property, enters spleen, lung and kidney channels, supplements qi and nourishes yin, tonifies spleen and kidney, and can secure essence and stop leukorrhagia; the codonopsis pilosula is neutral in nature, has the effects of invigorating spleen and tonifying lung, tonifying qi and promoting fluid production, and is mainly used for treating spleen and stomach weakness, poor appetite and loose stool and qi and blood deficiency; licorice root, radix Glycyrrhizae is neutral in nature, enters heart, spleen, lung and stomach meridians, regulates the middle warmer, relieves urgency, moistens lung, detoxifies toxicity, and coordinates the effects of the other drugs. The astragalus, the Chinese yam, the codonopsis pilosula and the liquorice are combined to play the functions of tonifying qi and spleen and improving the digestion and absorption functions of organisms, and are monarch drugs in the formula.
The honeysuckle is cold in nature, enters lung, heart, stomach and large intestine channels, clears away heat and toxic materials, cools and disperses wind heat, and can resist bacteria, viruses, relieve fever and enhance immunity; the isatis root is cold in nature, enters heart and stomach channels, has strong immunoregulation function, can promote spleen development, increase the number of white blood cells and lymphocytes, and promote synthesis and secretion of antibodies. Honeysuckle and isatis root are ministerial drugs in the prescription.
The medlar has mild nature, enters liver and kidney channels, can regulate immunity, and has the effects of resisting oxidation, resisting tumor, resisting fatigue, protecting liver, expelling toxin and the like; eucommia bark, cortex Eucommiae has warm nature, enters liver and kidney meridians, tonifies liver and kidney, and strengthens tendons and bones. The combination of the two can tonify liver and kidney, and the formula is used as an adjuvant drug.
The Chinese angelica, being a guiding drug in the formula, is warm in nature, enters liver, heart and spleen channels, can tonify blood, activate blood, moisten dryness and smooth intestines, and is mainly used for treating various diseases caused by blood abundance.
The whole formula uses the astragalus root, the yam, the codonopsis pilosula and the liquorice to tonify the middle-jiao and qi, promote the absorption capacity of the digestive system of the body and balance the cold and cool qi of the honeysuckle and the isatis root; the honeysuckle and the isatis root have the main effects of clearing heat and removing toxicity and are matched with monarch drugs for replenishing qi and invigorating spleen to achieve the effects of eliminating evil and strengthening body resistance and enhancing body immunity; the medlar and the eucommia bark eliminate liver and kidney symptoms caused by various toxins, remarkably improve the curative effect of the prescription and accelerate the recovery of sick livestock; dang Gui can tonify qi and blood, and strengthen the spleen-invigorating and stomach-harmonizing effect of monarch drug. The traditional Chinese medicine preparation mainly has the effects of strengthening the middle-jiao and replenishing qi, resisting virus and increasing qi, tonifying qi and blood, strengthening spleen and stomach by compatibility of the traditional Chinese medicines, achieves the effects of strengthening body resistance and eliminating evil, resisting virus and enhancing immunity, clearing heat and removing toxicity, strengthening heart and invigorating spleen and protecting liver and kidney by digestion and absorption of organs of a body, comprehensively regulates and rapidly improves the immunity of livestock and poultry, enhances the capability of the body for removing viruses, bacteria and other foreign matters, removes harmful substances in intestinal tract, can synergistically control immunosuppressive syndromes caused by mycotoxin and viral infection diseases such as ring disease, blue ear disease, pseudorabies, canine parvovirus, foot-and-mouth disease, influenza, diarrhea, bursal disease and the like, prevents and resists various diseases caused by viruses and bacteria in the growth process of livestock and poultry, and has good effect.
Compared with conventional chemical medicines, the traditional Chinese medicine feed additive has no toxic or side effect, does not generate drug resistance, and can be used as a feed additive for daily feed. In practical application, the traditional Chinese medicine formula is used as a feed additive and added into feed in an amount of 1 kg/ton of feed, and the feed is mixed with the feed for feeding livestock and poultry every month for 10 days, so that the disease resistance of the livestock and poultry can be obviously improved. According to investigation and statistics, during the epidemic period of African swine fever, no sick pig occurs in a pig farm in which the traditional Chinese medicine feed additive is mixed in the feed, and no sick chicken occurs in a chicken farm in which the traditional Chinese medicine feed additive is mixed in the feed during the epidemic period of the fowl plague, which shows that the traditional Chinese medicine feed additive can improve the antibody level of the livestock and poultry body, enhance the resistance of the livestock and poultry, and relieve the immune suppression syndrome caused by various reasons.
On the other hand, in the traditional Chinese medicine feed additive, honeysuckle and isatis root can be used for preventing and treating carbuncle, uterine erosion, leucorrhea, fishy smell, abortion and dead fetus, medlar and eucommia bark can be used for tonifying liver and kidney, protecting reproductive system and improving the conditions of oestrus, abortion and the like of livestock and poultry, and angelica can be used for treating infertility caused by anemia, blood stasis and anemia. Therefore, the traditional Chinese medicine prescription takes the astragalus, the Chinese yam, the codonopsis pilosula and the liquorice as monarch drugs for replenishing qi to invigorate the spleen and improving the immunity, takes the honeysuckle and the isatis root as ministerial drugs, takes the medlar and the eucommia ulmoides as adjuvant drugs and takes the angelica as conductant drugs, and the components are mutually matched, so that the antibody level of a sow can be improved, the health of a reproductive system is improved, the secretion in a female animal body is regulated, the conditions of abortion, stillbirth, repeated mating sterility and the like are obviously reduced, and the resistance of young animals can be enhanced.
Preferably, the traditional Chinese medicine additive comprises the following raw materials in parts by weight: 13-17 parts of astragalus membranaceus, 13-17 parts of Chinese yam, 11-13 parts of codonopsis pilosula, 6-9 parts of liquorice, 6-9 parts of honeysuckle, 12-14 parts of isatis root, 13-17 parts of wolfberry, 12-14 parts of eucommia ulmoides and 13-17 parts of angelica sinensis.
Preferably, the traditional Chinese medicine additive comprises the following raw materials in parts by weight: 15 parts of astragalus, 15 parts of Chinese yam, 12 parts of codonopsis pilosula, 8 parts of liquorice, 8 parts of honeysuckle, 13 parts of isatis root, 15 parts of medlar, 13 parts of eucommia bark and 15 parts of angelica.
In a second aspect, the embodiment of the invention also provides a preparation method of the traditional Chinese medicine feed additive for improving the immunity of the animal organism, which comprises the steps of cleaning and drying the raw materials, respectively crushing the raw materials to the particle size of less than 0.18mm, weighing the raw materials according to the weight part ratio, and mixing the raw materials to obtain the traditional Chinese medicine feed additive.
The preparation method is simple and convenient to operate, and can be used for small-batch production and large-scale production.
In a third aspect, the embodiment of the invention also provides a feed for improving the immunity of animal organisms, and the feed contains the traditional Chinese medicine feed additive.
In a fourth aspect, the embodiment of the invention also provides a preparation method of the feed for improving the immunity of the animal organism, the traditional Chinese medicine feed additive is mixed with other raw materials to prepare the feed, and the mass content of the traditional Chinese medicine feed additive in the feed is 0.8-1.2 per mill. Other raw materials in the feed can be selected according to breeding requirements by referring to raw materials used in feeds such as complete feed, energy feed, protein feed, mineral supplement and the like, such as soybean meal, grains, grease, meat and bone meal and the like, and the traditional Chinese medicine feed additive can also be directly mixed with the complete feed, the energy feed, the protein feed, the mineral supplement and the like.
Preferably, the mass content of the traditional Chinese medicine feed additive in the feed is 1 per mill.
Preferably, the other raw materials include soybean meal, grains, grease and meat and bone meal.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail with reference to the following embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
Example 1
The embodiment of the invention provides a traditional Chinese medicine feed additive for improving the immunity of animal organisms, which comprises the following raw materials: 15g of astragalus, 15g of Chinese yam, 12g of codonopsis pilosula, 8g of liquorice, 8g of honeysuckle, 13g of isatis root, 15g of medlar, 13g of eucommia and 15g of angelica.
The preparation method of the feed additive comprises the following steps: cleaning and drying radix astragali, rhizoma Dioscoreae, radix Codonopsis, Glycyrrhrizae radix, flos Lonicerae, radix Isatidis, fructus Lycii, Eucommiae cortex and radix Angelicae sinensis respectively, pulverizing to particle size less than 0.18mm respectively, weighing the pulverized raw materials according to the above Chinese medicinal feed additive, and mixing to obtain the final product.
Example 2
The embodiment of the invention provides a traditional Chinese medicine feed additive for improving the immunity of animal organisms, which comprises the following raw materials: 13g of astragalus, 13g of Chinese yam, 11g of codonopsis pilosula, 6g of liquorice, 6g of honeysuckle, 12g of isatis root, 13g of medlar, 12g of eucommia and 13g of angelica.
The preparation method of the feed additive is the same as that of example 1.
Example 3
The embodiment of the invention provides a traditional Chinese medicine feed additive for improving the immunity of animal organisms, which comprises the following raw materials: 17g of astragalus, 17g of Chinese yam, 13g of codonopsis pilosula, 9g of liquorice, 9g of honeysuckle, 14g of isatis root, 17g of medlar, 14g of eucommia and 17g of angelica.
The preparation method of the feed additive is the same as that of example 1.
Example 4
The embodiment of the invention provides a traditional Chinese medicine feed additive for improving the immunity of animal organisms, which comprises the following raw materials: 10g of astragalus, 10g of Chinese yam, 10g of codonopsis pilosula, 5g of liquorice, 5g of honeysuckle, 10g of isatis root, 10g of medlar, 10g of eucommia and 10g of angelica.
The preparation method of the feed additive is the same as that of example 1.
Example 5
The embodiment of the invention provides a traditional Chinese medicine feed additive for improving the immunity of animal organisms, which comprises the following raw materials: 20g of astragalus, 20g of Chinese yam, 15g of codonopsis pilosula, 10g of liquorice, 10g of honeysuckle, 15g of isatis root, 20g of medlar, 15g of eucommia and 20g of angelica.
The preparation method of the feed additive is the same as that of example 1.
Example 6
The embodiment of the invention provides a pig feed, which comprises the feed additive obtained in the embodiment 1 and a complete pig feed, wherein the content of the feed additive is 1wt per mill.
Example 7
The embodiment of the invention provides chicken feed which comprises the feed additive obtained in the embodiment 1 and complete feed, wherein the content of the feed additive is 1wt per mill.
Comparative example 1
The comparative example provides a traditional Chinese medicine feed additive for improving the immunity of animal organisms, based on example 1, honeysuckle is replaced by fructus forsythiae which has similar drug property and drug effect, and the traditional Chinese medicine feed additive specifically comprises the following raw materials: 15g of astragalus, 15g of Chinese yam, 12g of codonopsis pilosula, 8g of liquorice, 8g of fructus forsythiae, 13g of isatis root, 15g of medlar, 13g of eucommia and 15g of angelica.
The preparation method is the same as example 1.
Comparative example 2
The comparative example provides a traditional Chinese medicine feed additive for improving the immunity of animal organisms, based on example 1, astragalus is replaced by bighead atractylodes rhizome with similar drug property and drug effect, and the traditional Chinese medicine feed additive specifically comprises the following raw materials: 15g of bighead atractylodes rhizome, 15g of Chinese yam, 12g of codonopsis pilosula, 8g of liquorice, 8g of honeysuckle, 13g of isatis root, 15g of Chinese wolfberry, 13g of eucommia bark and 15g of Chinese angelica.
The preparation method is the same as example 1.
Comparative example 3
The comparative example provides a traditional Chinese medicine feed additive for improving the immunity of animal organisms, based on example 1, eucommia ulmoides is replaced by teasel roots with similar medicine properties and effects, and the traditional Chinese medicine feed additive specifically comprises the following raw materials: 15g of astragalus, 15g of Chinese yam, 12g of codonopsis pilosula, 8g of liquorice, 8g of honeysuckle, 13g of isatis root, 15g of medlar, 13g of teasel root and 15g of angelica.
The preparation method is the same as example 1.
Effect example 1
In 2019, circovirus appears in a certain pig farm in Qinhuang island city, Hebei province. Infected piglets and grown pigs were randomly divided into 7 groups, including 3 test groups, 3 control groups and 1 blank group, respectively. 3 test groups respectively adopt the traditional Chinese medicine feed additive disclosed by the embodiment 1-3 of the invention, and the traditional Chinese medicine feed additive is added into complete feed by 1 per mill of additive amount and is freely ingested by pigs; 3 control groups adopt the traditional Chinese medicine feed additive of comparative examples 1-3 of the invention, are added into complete feed by 1 per mill of addition amount, and are freely ingested by pigs; the blank group was fed with the same complete feed and no other herbal additives were used throughout. Feeding continuously for 7 days, and counting the cumulative rehabilitation quantity of each group every day. The results are shown in tables 1 and 2.
TABLE 1 piglet recovery
Note: relative to blank P < 0.05.
TABLE 2 recovery of growing pigs
Note: relative to blank P < 0.05.
The experimental results show that compared with the blank group, the piglets and the bred pigs of the test group and the control group have higher recovery rate and lower feed-meat ratio, while the recovery rate of the test group is obviously higher than that of the control group and the feed-meat ratio is lower than that of the control group. The results in tables 1 and 2 show that the traditional Chinese medicine feed additive provided by the invention can improve the immunity and health level of pigs.
Effect example 2
The effect example provides the influence of the traditional Chinese medicine feed additives of the examples 1 to 3 and the comparative examples 1 to 3 on the prevention of the abortion of the sows.
Experimental animals: in 2019, 210 sows of the 4 th gestation age are selected in a certain pig farm in Qinhuang island, Hebei province.
The test method comprises the following steps: the sows with the reproductive age are randomly divided into 7 groups, the test group and the control group are respectively fed with the complete feed of the pregnant sows mixed with 1 per thousand of the traditional Chinese medicine feed additives obtained in the examples 1-3 and the comparative examples 1-3 for 5 days per month, and the pregnant sows without the traditional Chinese medicine feed additives are normally fed with the complete feed in the rest time. After the gestation period, the test group and the control group are respectively fed with the pregnant sow complete feed mixed with 1 per mill of the traditional Chinese medicine feed additives obtained in the examples 1-3 and the comparative examples 1-3 for 5 days per month, and the pregnant sow complete feed without the traditional Chinese medicine additive is normally fed in the rest time.
The blank group is fed with the complete feed of the pregnant sow before the pregnancy period, and is fed with the complete feed of the pregnant sow after the pregnancy period.
The average litter size, litter flow, dead and weak (birth weight less than 1kg, no sucking, no normal standing) of each group was statistically recorded. The results are shown in Table 3.
TABLE 3 influence of Chinese medicinal feed additive on the prevention of sow miscarriage
Note: relative to blank P < 0.05.
As can be seen from the experimental results, the cases of abortion, stillbirth and weak fetuses of the sows can be obviously reduced in the groups of examples 1 to 3, the average body weight of the live piglets can be improved, and the results in all aspects are superior to those of each proportional group.
Effect example 3
In 2019, infectious laryngotracheitis appears in a chicken farm in Qinhuang island, Hebei province, and uninfected healthy adult chickens are selected to be randomly divided into 7 groups respectively, wherein the 7 groups comprise 3 test groups, 3 control groups and 1 blank group. 3 test groups respectively adopt the traditional Chinese medicine feed additive disclosed by the embodiment 1-3 of the invention, and the traditional Chinese medicine feed additive is added into complete feed by 1 per mill of additive amount and is freely ingested by chickens; 3 control groups adopt the traditional Chinese medicine feed additive of comparative examples 1-3 of the invention, are added into complete feed by 1 per mill of addition amount, and are freely ingested by chickens; the blank group was fed with the same complete feed and no other herbal additives were used throughout. Feeding continuously for 7 days, and counting the total number of sick chickens on the day (subtracting the number of convalescence if the infected chickens are healed) every day. The results are shown in Table 4.
TABLE 4 infection of chickens
Note: relative to blank P < 0.05.
As can be seen from the above experimental results, compared with the blank group, the chickens of the test group and the control group have higher resistance, are not easy to suffer from diseases, and have lower feed-meat ratio. The resistance of the test group is obviously higher than that of the control group, the number of the affected diseases is less, the patients can recover quickly after the diseases are affected, and the feed conversion ratio is lower than that of the control group. The results in table 4 demonstrate that the traditional Chinese medicine feed additive provided by the invention can improve the immunity and health level of chickens.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents or improvements made within the spirit and principle of the present invention should be included in the scope of the present invention.
Claims (8)
1. The traditional Chinese medicine feed additive for improving the immunity of animal organisms is characterized by comprising the following raw materials in parts by weight: 10-20 parts of astragalus membranaceus, 10-20 parts of Chinese yam, 10-15 parts of codonopsis pilosula, 5-10 parts of liquorice, 5-10 parts of honeysuckle, 10-15 parts of isatis root, 10-20 parts of wolfberry, 10-15 parts of eucommia ulmoides and 10-20 parts of angelica sinensis.
2. The traditional Chinese medicine feed additive for improving the immunity of animal organisms according to claim 1, which is characterized by comprising the following raw materials in parts by weight: 13-17 parts of astragalus membranaceus, 13-17 parts of Chinese yam, 11-13 parts of codonopsis pilosula, 6-9 parts of liquorice, 6-9 parts of honeysuckle, 12-14 parts of isatis root, 13-17 parts of wolfberry, 12-14 parts of eucommia ulmoides and 13-17 parts of angelica sinensis.
3. The traditional Chinese medicine feed additive for improving the immunity of animal organisms according to claim 2, which is characterized by comprising the following raw materials in parts by weight: 15 parts of astragalus, 15 parts of Chinese yam, 12 parts of codonopsis pilosula, 8 parts of liquorice, 8 parts of honeysuckle, 13 parts of isatis root, 15 parts of medlar, 13 parts of eucommia bark and 15 parts of angelica.
4. The preparation method of the traditional Chinese medicine feed additive for improving animal body immunity as claimed in any one of claims 1 to 3, wherein the raw materials are cleaned and dried, then respectively crushed to have a particle size of less than 0.18mm, and the raw materials are weighed according to the weight part ratio and mixed to obtain the traditional Chinese medicine feed additive.
5. A feed for improving the immunity of an animal body, which is characterized by comprising the traditional Chinese medicine feed additive for improving the immunity of the animal body according to any one of claims 1 to 3.
6. The preparation method of the feed for improving the immunity of the animal organism as claimed in claim 5, wherein the feed is prepared by mixing the traditional Chinese medicine feed additive with other raw materials, and the mass content of the traditional Chinese medicine feed additive in the feed is 0.8-1.2 per mill.
7. The preparation method of the feed for improving the immunity of the animal body as claimed in claim 6, wherein the mass content of the traditional Chinese medicine feed additive in the feed is 1 per mill.
8. The method for preparing the feed for improving the immunity of the animal body according to claim 6 or 7, wherein the other raw materials comprise soybean meal, grains, grease and meat and bone meal.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202010758728.6A CN111789190A (en) | 2020-07-31 | 2020-07-31 | Traditional Chinese medicine feed additive for improving animal organism immunity, feed and preparation method |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202010758728.6A CN111789190A (en) | 2020-07-31 | 2020-07-31 | Traditional Chinese medicine feed additive for improving animal organism immunity, feed and preparation method |
Publications (1)
Publication Number | Publication Date |
---|---|
CN111789190A true CN111789190A (en) | 2020-10-20 |
Family
ID=72828184
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202010758728.6A Pending CN111789190A (en) | 2020-07-31 | 2020-07-31 | Traditional Chinese medicine feed additive for improving animal organism immunity, feed and preparation method |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN111789190A (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112586622A (en) * | 2020-12-25 | 2021-04-02 | 河南佑民生物科技股份有限公司 | Fattening pig health feed for promoting digestion and improving immunity of organism and preparation method thereof |
CN112690365A (en) * | 2020-12-03 | 2021-04-23 | 内蒙古优然牧业有限责任公司 | Feed additive and preparation method and application thereof |
CN112868937A (en) * | 2021-02-06 | 2021-06-01 | 南宁硕发农业开发有限公司 | Chicken feed for improving disease resistance and survival rate, preparation method and feeding method thereof |
Citations (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102308929A (en) * | 2011-09-09 | 2012-01-11 | 上海交通大学 | Chinese herbal medicine feed additive for enhancing chicken immunity, preparation method and feed |
CN104012807A (en) * | 2014-06-18 | 2014-09-03 | 广东金品动物营养有限公司 | Antiviral compound vitamin premix feed preparation for livestock as well as preparation method and application of preparation |
CN104161204A (en) * | 2013-07-15 | 2014-11-26 | 河南联合英伟饲料有限公司 | Pig growth promoting Chinese herbal feed additive and applications thereof |
CN104161166A (en) * | 2013-07-17 | 2014-11-26 | 河南联合英伟饲料有限公司 | Feed additive capable of preventing and treating viral and bacterial diseases of livestock and poultry, preparation method and application thereof |
CN105265783A (en) * | 2015-11-22 | 2016-01-27 | 杨书戈 | Healthcare Chinese medicinal herb feed additive for laying ducks |
CN106135730A (en) * | 2016-06-28 | 2016-11-23 | 宿松飞翔生态养殖有限公司 | A kind of antibacterial bacteriostatic livestock fodder additives |
CN107496707A (en) * | 2017-10-20 | 2017-12-22 | 安庆市柯旷动物药业有限公司 | A kind of Chinese medicine composition for strengthening immunity of livestock |
CN107535715A (en) * | 2017-10-16 | 2018-01-05 | 六安恒佳生物科技有限公司 | A kind of Chinese herbal feed additive for preventing Sow abortion stillborn foetus and preparation method thereof |
CN110463826A (en) * | 2019-08-19 | 2019-11-19 | 王万明 | A kind of livestock feed formula |
CN110692820A (en) * | 2019-11-26 | 2020-01-17 | 陈春 | Traditional Chinese medicine feed additive for improving autoimmune function of pigs and preparation method thereof |
-
2020
- 2020-07-31 CN CN202010758728.6A patent/CN111789190A/en active Pending
Patent Citations (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102308929A (en) * | 2011-09-09 | 2012-01-11 | 上海交通大学 | Chinese herbal medicine feed additive for enhancing chicken immunity, preparation method and feed |
CN104161204A (en) * | 2013-07-15 | 2014-11-26 | 河南联合英伟饲料有限公司 | Pig growth promoting Chinese herbal feed additive and applications thereof |
CN104161166A (en) * | 2013-07-17 | 2014-11-26 | 河南联合英伟饲料有限公司 | Feed additive capable of preventing and treating viral and bacterial diseases of livestock and poultry, preparation method and application thereof |
CN104012807A (en) * | 2014-06-18 | 2014-09-03 | 广东金品动物营养有限公司 | Antiviral compound vitamin premix feed preparation for livestock as well as preparation method and application of preparation |
CN105265783A (en) * | 2015-11-22 | 2016-01-27 | 杨书戈 | Healthcare Chinese medicinal herb feed additive for laying ducks |
CN106135730A (en) * | 2016-06-28 | 2016-11-23 | 宿松飞翔生态养殖有限公司 | A kind of antibacterial bacteriostatic livestock fodder additives |
CN107535715A (en) * | 2017-10-16 | 2018-01-05 | 六安恒佳生物科技有限公司 | A kind of Chinese herbal feed additive for preventing Sow abortion stillborn foetus and preparation method thereof |
CN107496707A (en) * | 2017-10-20 | 2017-12-22 | 安庆市柯旷动物药业有限公司 | A kind of Chinese medicine composition for strengthening immunity of livestock |
CN110463826A (en) * | 2019-08-19 | 2019-11-19 | 王万明 | A kind of livestock feed formula |
CN110692820A (en) * | 2019-11-26 | 2020-01-17 | 陈春 | Traditional Chinese medicine feed additive for improving autoimmune function of pigs and preparation method thereof |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112690365A (en) * | 2020-12-03 | 2021-04-23 | 内蒙古优然牧业有限责任公司 | Feed additive and preparation method and application thereof |
CN112586622A (en) * | 2020-12-25 | 2021-04-02 | 河南佑民生物科技股份有限公司 | Fattening pig health feed for promoting digestion and improving immunity of organism and preparation method thereof |
CN112868937A (en) * | 2021-02-06 | 2021-06-01 | 南宁硕发农业开发有限公司 | Chicken feed for improving disease resistance and survival rate, preparation method and feeding method thereof |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN101869224B (en) | Feed additive for improving lactation performance of lactating sows and preparation method thereof | |
CN111789190A (en) | Traditional Chinese medicine feed additive for improving animal organism immunity, feed and preparation method | |
CN101698024B (en) | Traditional Chinese medicine for treating respiratory diseases and promoting growth for swine and preparation method thereof | |
CN102872396B (en) | Complex Chinese herbal medicine preparation for treating diarrhea of piglets and preparation method thereof | |
CN101543589A (en) | Compound pharmaceutical composition for curing virus diseases of animals and preparation method thereof | |
CN107349385A (en) | One group is used for fermented tcm composition that live pig nonreactive cultivates and preparation method thereof | |
CN111067974A (en) | Chinese herbal medicine preparation for preventing African swine fever virus and preparation method thereof | |
CN108112785A (en) | A kind of Chinese medicine pig feed additive, preparation method and its pannage | |
CN102038842A (en) | Medicament for improving production performance of pigs and preparation method thereof | |
CN106666099A (en) | Pig feed preventing and treating gastrointestinal diseases | |
CN101543601B (en) | Compound pharmaceutical composition for preventing and curing respiratory diseases in animals and preparation method thereof | |
CN104208163B (en) | It is a kind of improve animal immunizing power Chinese veterinary medicinal composition, using and preparation method thereof | |
CN101209294A (en) | Chinese medicinal granule for animals with cough and asthma relieving efficacy | |
CN105168807B (en) | The Chinese medicine composition and preparation method thereof for treating pig blue-ear disease | |
CN116370542B (en) | Traditional Chinese medicine composition for preventing and treating porcine reproductive and respiratory syndrome as well as preparation method and application thereof | |
CN105796978A (en) | Traditional Chinese medicine prescription for treating porcine reproductive and respiratory syndrome (PRRS) as well as preparation method and application method | |
CN104147586A (en) | Chinese herbal medicine composition and fodder for preventing and treating cold irritable enteritis of quails | |
CN107308415A (en) | One group is used to treat Chinese medicine composition of cad pig and preparation method thereof | |
CN103800464B (en) | A kind of Chinese medicine composition for the treatment of yellow and white dysentery of piglet | |
CN106912732A (en) | A kind of feed addictive for treating diarrhea of pigs and its application | |
CN103142702A (en) | Chinese herbal medicine injection liquid for treating porcine reproductive and respiratory syndrome and preparation method thereof | |
CN103656366B (en) | A kind ofly treat Chinese medicine of diarrhea of weaned piglets in winter and preparation method thereof | |
CN107998332B (en) | Traditional Chinese medicine composition for treating porcine reproductive and respiratory syndrome and application thereof | |
CN102274326B (en) | Pure Chinese medicinal combination for treating piglet yellow-white dysentery and preparation method thereof | |
CN110812389A (en) | Soluble granule for improving pig immunity and preparation method thereof |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20201020 |
|
RJ01 | Rejection of invention patent application after publication |