CN106912732A - A kind of feed addictive for treating diarrhea of pigs and its application - Google Patents

A kind of feed addictive for treating diarrhea of pigs and its application Download PDF

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Publication number
CN106912732A
CN106912732A CN201710277860.3A CN201710277860A CN106912732A CN 106912732 A CN106912732 A CN 106912732A CN 201710277860 A CN201710277860 A CN 201710277860A CN 106912732 A CN106912732 A CN 106912732A
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parts
feed addictive
pigs
diarrhea
ground
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CN106912732B (en
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罗冠勇
梅文莉
戴好富
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Institute of Tropical Bioscience and Biotechnology Chinese Academy of Tropical Agricultural Sciences
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Institute of Tropical Bioscience and Biotechnology Chinese Academy of Tropical Agricultural Sciences
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Abstract

The present invention relates to a kind of feed addictive for treating diarrhea of pigs and its application, belong to field of feed.Component of the present invention including following parts by weight:First 10 35 parts of the courage in ground, 15 45 parts of galangal, 10 25 parts of the Radix Astragali, 10 20 parts of Radix Glycyrrhizae.Feed addictive of the present invention have functions that it is clearing heat and detoxicating, dry, astringing to arrest diarrhea, anti-inflammation and enhancing immunity of organisms, good effect is shown in piglet, sow, the diarrhoeal diseases of boar, experiment shows, this kind of feed addictive treatment diarrhea of pigs has good effect and convenient material drawing, instant effect, low cost, it is well suited for raiser to use, any side effect is not found in the treatment yet, drug safety, have no drug resistance, curative effect stabilization, Swinery immunity power can be improved again, cure rate reaches 90%, has a extensive future.

Description

A kind of feed addictive for treating diarrhea of pigs and its application
Technical field
The present invention relates to field of feed, and in particular to a kind of feed addictive for treating diarrhea of pigs and its application.
Background technology
Diarrhoea is one of main clinic symptoms of chitling tract disease, and the diarrhea of pigs disease being on the rise is current scale pig industry One chronic disease of development, either has generation in modern scale raising or middle-size and small-size or casual household cultivation, enjoys pig industry The attention and concern on boundary.Although the diarrhea of pigs death rate is not high, pig food refusal, vomiting, immunocyte decline and initiation can be caused Other symptoms, relatively more refractory treatment.The reason for causing diarrhea of pigs is a lot, for example, influenceed by seasonal variations factor, infect virus or thin Bacterium etc..The viral species of virus diarrhea are caused mainly to be infectious marcy agent (transmissible Gastroenteritis of swine, TGE), Porcine epidemic diarrhea virus (Porcine Epidemic Diarrhea, PED), rotavirus (duovirus) etc.;Causing the germ of bacterial diarrhea mainly has Escherichia coli (Escherichia Coli), salmonella (salmonella) etc..Essentially from sick pig, virus is present in intestinal villus epithelial tissue and intestines to the infection sources Mesentery lymph node, after being discharged with excrement, pollutes environment, feed, drinking-water, the vehicles and apparatus etc. and infects.Main clinic Symptom is watery diarrhea, or with vomiting during suffering from diarrhoea.The weight of symptom is variant with the size at age, and the age gets over Small, symptom is heavier.According to relevant report, diarrhea of weaned piglets rate reaches 10%-20% in 20%-30% or so, the death rate, even if Recover, it grows and can also be severely impacted.Fattening pig after suffering from diarrhoea, death rate 1%-3%.Adult Pig symptom compared with Gently, the only performance having is vomitted, and severe one watery diarrhea 3-4 days can self-healing.
Treatment diarrhea of pigs often uses antibiotic at present, and it also with promotion growth of animal, is improved while preventing and curing diseases Effect of feed conversion rate, it can be seen that antibiotic has obvious effect as feed addictive application.But the length of antibiotic Phase, with the increase of additive capacity, effect also can worse and worse, so as to cause the treatment of disease difficult using drug resistance is easily produced Degree is increasing, therefore studies the medicine or feed addictive of a kind of safely and effectively treatment diarrhea of pigs to development green animal husbandry Have important practical significance.
Chinese herbal medicine is the product of the distinctive traditional Chinese medical theory of China and practice, its aboundresources, wide variety, with day So, have no toxic side effect, without chemicals residue, be not likely to produce the resistance to the action of a drug the features such as.Chinese herbal medicine has obtained wider in field of fodder General application, but there is the shortcomings of composition is more complicated, preparation technology is more complicated in existing feed addictive.
The B of Chinese patent CN 104886345 disclose Chinese medicine preparation and its preparation side of a kind of preventing post-weaning diarrhea Method, including following component:Dandelion extract, Astragalus Root P.E, Andrographis Paniculata, houttuynia extract, glucose, wheat Bud, rhizoma pinellinae praeparata, Semen Lablab Album, hawthorn and montmorillonite.The Chinese medicine preparation has significant antibacterial, antivirus action, can prevent piglet Diarrhoea phenomenon after wean, can meet the nutritional need of piglet, improve function of intestinal canal, but the component being related to is more, and prepare work Skill is more complicated.
Chinese patent CN105454695A discloses a kind of feed addictive for preventing and treating diarrhea of pigs, including such as the following group Point:Bone meal, lysozyme, coriolan.The feed addictive is reasonable, evident in efficacy without western medicine composition, compatibility, can significantly reduce Diarrhea of pigs rate, but its preparation technology is complex.
The content of the invention
It is an object of the invention to provide a kind of feed addictive of natural treatment diarrhea of pigs, the feed addictive is by medium-height grass Medicine is constituted, and has synergistic function between each component, and evident in efficacy, preparation process is simple can not only improve controlling for diarrhea of pigs More rate, moreover it is possible to improve the immunity of pig, reduces the mutual infection of swinery.
The technical solution used in the present invention is:
A kind of feed addictive for treating diarrhea of pigs, including following parts by weight component:Ground courage head (including spend ground courage in vain Grass) 10-35 parts, galangal 15-45 parts, Radix Astragali 10-25 parts and Radix Glycyrrhizae 10-20 parts.
Preferably, a kind of feed addictive for treating diarrhea of pigs that the present invention is provided includes the component of following parts by weight: 10-25 parts, galangal 15-25 parts, Radix Astragali 10-20 parts, Radix Glycyrrhizae 10-20 parts of the courage head in ground.
Preferably, a kind of feed addictive for treating diarrhea of pigs that the present invention is provided includes the component of following parts by weight: First 10 parts of the courage in ground, 15 parts of galangal, 15 parts of the Radix Astragali, 20 parts of Radix Glycyrrhizae.
Preferably, a kind of feed addictive for treating diarrhea of pigs, including one or two in amino acid, vitamin Active component.The amino acid is methionine, lysine etc., and the vitamin is vitamin A, vitamin C, vitamin D, dimension Raw element E, vitamin K etc..
Additionally, the feed addictive that the present invention is provided should in the piglet with diarrhoeal diseases, sow, the basal diet of boar With.
Preferably, a kind of consumption of feed addictive for treating diarrhea of pigs is the 2-6% of pig basal diet weight.
The present invention provide feed addictive have it is clearing heat and detoxicating, dry, astringing to arrest diarrhea, anti-inflammation, enhancing body exempt from Effect of epidemic disease power, good effect is shown in piglet, sow, the diarrhoeal diseases of boar.
In each component of described feed addictive, ground courage head is composite family Elephantopus plant elephants-foot The herb of (Elephantopus suaber L.), it is bitter, cool in nature, have clearing heat and detoxicating, anti-inflammation, swelling diuretic, eliminating the phlegm it Effect, cure cold, bacterium, gastroenteritis, tonsillitis, sphagitis, nephritic dropsy, conjunctivitis, the disease such as furuncle, be traditional Chinese medical science common medicine. Ground courage head is containing various important chemical compositions such as Sesquiterpene lactones, triterpenes, flavonoids.Galangal is Zingiber Alpinia plants The rhizome of galangal (Alpinia officinarum Hance), pungent, heat, warm stomach, cold dispelling, help digestion analgesic, its chemical composition master Will be including volatile oil, flavonoids, diaryl heptane class, sterols, Phenylpropanoid Glycosides class, glycoside etc..Pharmaceutical research shows height There is galingal antibacterial action, antivirus action, anti diar rhea, antitumor action, antioxidation, anti-gastrointestinal tract bleeding to act on, resist Ulcer function and the protective effects on gastric mucosa etc..The Radix Astragali is the pulse family Astragalus Radix Astragali (Astragalus membranaceus (Fisch.) Bunge.) root, sweet, slightly warm in nature, for treating weakness of the spleen and the stomach, poor appetite.The Radix Astragali contain polysaccharide, triterpene, Flavones isoreactivity composition.Pharmacological evaluation and clinical report show, the Radix Astragali in immunological regulation, antitumor, antiviral, diabetes, prolong The aspects such as slow aging play an important roll.Radix Glycyrrhizae is pulse family glycyrrhiza genus Radix Glycyrrhizae (Glycyrrhiza uralensis Fisch) root or root-like stock, mild-natured, taste are sweet, and with mending, benifit gas, clearing heat and detoxicating, anti-inflammation, mediation property of medicine, mitigation medicine are strong The effect of property.Existing research report shows that Radix Glycyrrhizae contains the main actives such as flavone compound, licorice polysaccharide, glycyrrhizic acid.
Compared with prior art, the beneficial effects of the invention are as follows:Feed addictive key component of the invention is ground courage head, Galangal, the Radix Astragali, Radix Glycyrrhizae, between each component have synergistic function, for TGE, rotavirus, The diarrhea of pigs that Porcine epidemic diarrhea virus causes has significant therapeutic effect, and cure rate is up to 90%.Feed of the invention adds Plus agent have functions that it is clearing heat and detoxicating, dry, astringing to arrest diarrhea, anti-inflammation and enhancing immunity of organisms, medicinal material is readily available, into This low, preparation process is simple, is especially suitable for the use of raiser, and such as courage head grass is grown in the humidities such as field, small stream side Ground, convenient material drawing, antibiotic property is strong, and Baoshang food materials are used as in Hainan.
Specific embodiment
Further describe the present invention with reference to specific embodiment, advantages of the present invention and feature will be with description and It is apparent.It should be understood that the embodiment is only exemplary, any limitation is not constituted to the scope of the present invention.This area Technical staff should be understood that without departing from the spirit and scope of the invention can to the details of technical solution of the present invention and Form is modified or is replaced, but these modifications or replacement each fall within protection scope of the present invention.
Embodiment 1:
This feed addictive includes the component of following parts by weight:It is first 10 parts of the courage in ground, 15 parts of galangal, 15 parts of the Radix Astragali, sweet 20 parts of grass.
Prepare and feeding method:
After each component is ground into the medicinal powder of the mesh of 100 mesh -120, mix in proportion, add water and boil half an hour, by pig basis Direct feeding in 4% addition daily ration of daily ration weight.Sooner or later once daily, continuous one week.Daily ration based on the daily ration A, formula is shown in Table 1.
Embodiment 2:
The weight portion of this feed addictive each component:First 10 parts of the courage in ground, 15 parts of galangal, 10 parts of the Radix Astragali, 10 parts of Radix Glycyrrhizae.
Prepare and feeding method:It is same as Example 1.
Embodiment 3:
The weight portion of this feed addictive each component:First 15 parts of the courage in ground, 25 parts of galangal, 20 parts of the Radix Astragali, 13 parts of Radix Glycyrrhizae.
Prepare and feeding method:It is same as Example 1.
Embodiment 4:
The weight portion of this feed addictive each component:First 35 parts of the courage in ground, 45 parts of galangal, 25 parts of the Radix Astragali, 20 parts of Radix Glycyrrhizae.
Prepare and feeding method:Embodiment 1 is identical.
Embodiment 5:
The weight portion of this feed addictive each component:It is same as Example 1.
Prepare and feeding method:Same as Example 1, difference is that the consumption of feed addictive is pig basal diet weight 2%.
Embodiment 6:
The weight portion of this feed addictive each component:It is same as Example 1.
Prepare and feeding method:Same as Example 1, difference is that the consumption of feed addictive is pig basal diet weight 6%.
Embodiment 7:
The weight portion of feed addictive each component:It is same as Example 1.
Prepare and feeding method:Same as Example 1, difference is daily ration B based on used daily ration, and formula is shown in Table 2。
Experiment 1:
Experiment packet:Selection be diagnosed as infection TGE ill piglet 180, every group 20, at random It is divided into 9 groups.
Feeding method:Feed addictive described in embodiment 1-4 is pressed the 4% of basal diet weight by the 1st to the 4th group respectively Add water and add direct feeding in basal diet A after boiling half an hour;5th group is pressed the feed addictive described in embodiment 5 The 2% of basal diet weight adds water after boiling half an hour and adds direct feeding in basal diet A;6th group by the institute of embodiment 6 The feed addictive stated adds water after boiling half an hour by the 6% of basal diet weight and adds direct feeding in basal diet A; 7th group the feed addictive described in embodiment 7 is added water by the 4% of basal diet weight boil half an hour after add basal diet Direct feeding in B;8th group is control group 1, only feeding basal diet A;9th group is control group 2, only feeding basal diet B;Sooner or later once daily, continuous one week.
Changes of weight and diarrhea of pigs cure rate of the record piglet during testing.Cure rate=1- diarrhoea heads number/experiment is total Head number × 100%.Result of the test is shown in Table 3.
Experiment 2:
Selection is diagnosed as the ill piglet 20 of infection rotavirus, by the feed addictive described in embodiment 1 by basis The 4% of daily ration weight adds water after boiling half an hour and adds direct feeding in basal diet A.Sooner or later once daily, continuous one Week.Changes of weight and diarrhea of pigs cure rate of the record piglet during testing.Cure rate=1- diarrhoea heads number/total head number of experiment × 100%.Result of the test is shown in Table 4.
Experiment 3:
Selection is diagnosed as the ill piglet 20 of infection Porcine epidemic diarrhea virus, by the feed addition described in embodiment 1 Agent adds water after boiling half an hour by the 4% of basal diet weight and adds direct feeding in basal diet A.The daily morning and evening one It is secondary, continuous one week.Changes of weight and diarrhea of pigs cure rate of the record piglet during testing.Cure rate=1- diarrhoea heads number/reality Test total head number × 100%.Result of the test is shown in Table 4.
Table 1:Basal diet A
Table 2:Basal diet B
Result of the test:
Table 3:The therapeutic effect of diarrhea of pigs
Table 4:Different virus cause the therapeutic effect of diarrhea of pigs
Result of the test shows:Embodiment 1-7 is respectively for the cure rate of the diarrhea of pigs of infection TGE 96.11%th, 90.15%, 91.37%, 90.26%, 92.57%, 98.65% and 90.88%, the cure rate of control group is 25.17%th, 21.33%;For infection rotavirus diarrhea of pigs cure rate for 97.74%, for infection pig epidemic The cure rate of the diarrhea of pigs of diarrhea virus is 96.67%, it is seen that each component of the present invention is by 10-35 parts of the courage head in ground, galangal 15-45 Part, Radix Astragali 10-25 parts, Radix Glycyrrhizae 10-20 parts of parts by weight are used in mixed way can obtain preferable therapeutic effect, cure rate reaches More than 90%, particularly each component weight portion are first 10 parts of the courage in ground, 15 parts of galangal, 15 parts of the Radix Astragali, 20 parts of Radix Glycyrrhizae, and additive is used Measure for 6% when therapeutic effect more preferably.By experiment 3 and the result of the test of table 4, this feed addictive is directed to infectiousness stomach The diarrhea of pigs that scorching virus, rotavirus, Porcine epidemic diarrhea virus cause has significant therapeutic effect.
Experiment 4:Feed addictive component screening test
1 group:The feed addictive that embodiment 1 is obtained.
2 groups:The weight portion of feed addictive each component:First 10 parts of the courage in ground, 15 parts of galangal, 15 parts of the bighead atractylodes rhizome, 20 parts of Poria cocos.
3 groups:The weight portion of feed addictive each component:10 parts of the bighead atractylodes rhizome, 15 parts of Poria cocos, 15 parts of the Radix Astragali, 20 parts of Radix Glycyrrhizae.
4 groups:The weight portion of feed addictive each component:10~18 parts of chrysanthemum, 5~10 parts of Chinese prickly ash, 2~5 parts of pineapple peel, side 1~3 part of 1~5 part of CedarLeaves, 1~5 part of garlic, 2~5 parts of the banksia rose, 1~3 part of the fleece-flower root and Poria cocos.
Experiment packet:Selection is diagnosed as the ill piglet 100 of infection TGE, is randomly divided into 5 groups, often Group 20.
Feeding method:1st to the 4th group of feed addictive adds water after boiling half an hour by the 4% of basal diet weight and adds Enter direct feeding in basal diet A;5th group is control group, only feeds basal diet A;Sooner or later once daily, continuous one week.
Changes of weight and diarrhea of pigs cure rate of the record piglet during testing.Cure rate=1- diarrhoea heads number/experiment is total Head number × 100%.Result of the test is shown in Table 5.
Result of the test:
Table 5:Feed addictive component screening test result
Result of the test shows:It is 96.11% to test 1 group of cure rate of diarrhea of pigs, higher than other test groups;As can be seen here, Ground courage head, galangal, the Radix Astragali and Radix Glycyrrhizae carry out compatibility, can not only give full play to respective advantage, and make with Synergistic With to diarrhea of pigs treatment with remarkable effect.
Experiment 5:Therapeutic effect contrast test in piglet, sow, boar
Experiment packet:Selection is diagnosed as the ill piglet 20 of infection TGE as 1 group, ill sow 20 as 2 groups, ill boar 20 as 3 groups.
Feeding method:The feed addictive described in embodiment 1 is added water by the 4% of basal diet weight respectively it is small to boil half When after add 1 group of experiment, 2 groups, direct feeding in 3 groups of basal diet.Daily ration uses basal diet A.The daily morning and evening one It is secondary, continuous one week.
Record changes of weight and diarrhea of pigs cure rate of each test group during testing.Cure rate=1- diarrhoea heads number/reality Test total head number × 100%.Result of the test is shown in Table 6.
Table 6:Therapeutic effect comparative test result in piglet, sow, boar
Result of the test shows:Test 1 group, 2 groups, 3 groups of cure rate be respectively 96.11%, 98.22%, 98.37%, can The cure rate seen in diarrhoeal diseases of the feed addictive of the present invention in piglet, sow, boar reaches more than 90%, treats pig abdomen Rush down and work well.

Claims (7)

1. a kind of feed addictive for treating diarrhea of pigs, it is characterised in that the component including following parts by weight:Ground courage head 10- 35 parts, galangal 15-45 parts, Radix Astragali 10-25 parts and Radix Glycyrrhizae 10-20 parts.
2. a kind of feed addictive for treating diarrhea of pigs according to claim 1, it is characterised in that including following weight portion Several components:10-25 parts, galangal 15-25 parts, Radix Astragali 10-20 parts, Radix Glycyrrhizae 10-20 parts of the courage head in ground.
3. a kind of feed addictive for treating diarrhea of pigs according to claim 1, it is characterised in that including following weight portion Several components:First 10 parts of the courage in ground, galangal is 15 parts, the Radix Astragali 15,20 parts of Radix Glycyrrhizae.
4. a kind of feed addictive for treating diarrhea of pigs according to claim 1, it is characterised in that the feed addictive Including one or two the active component in amino acid, vitamin.
5. a kind of feed addictive for treating diarrhea of pigs according to claim 1, it is characterised in that described ground courage head is replaced To spend elephants-foot in vain.
6. the feed addictive described in any one of claim 1-5 the piglet with diarrhoeal diseases, sow, boar basal diet Middle application.
7. a kind of application according to claim 6, it is characterised in that consumption of the feed addictive for treating diarrhea of pigs It is the 2-6% of pig basal diet weight.
CN201710277860.3A 2017-04-25 2017-04-25 Feed additive for treating pig diarrhea and application thereof Active CN106912732B (en)

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