CN105982995A - Specific traditional Chinese veterinary oral medicine for treating chronic hog cholera - Google Patents
Specific traditional Chinese veterinary oral medicine for treating chronic hog cholera Download PDFInfo
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- CN105982995A CN105982995A CN201610057866.5A CN201610057866A CN105982995A CN 105982995 A CN105982995 A CN 105982995A CN 201610057866 A CN201610057866 A CN 201610057866A CN 105982995 A CN105982995 A CN 105982995A
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- 206010008631 Cholera Diseases 0.000 title abstract 4
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- 241000282898 Sus scrofa Species 0.000 claims description 29
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- 229940100688 oral solution Drugs 0.000 claims description 12
- 239000000341 volatile oil Substances 0.000 claims description 9
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- GOLXNESZZPUPJE-UHFFFAOYSA-N spiromesifen Chemical compound CC1=CC(C)=CC(C)=C1C(C(O1)=O)=C(OC(=O)CC(C)(C)C)C11CCCC1 GOLXNESZZPUPJE-UHFFFAOYSA-N 0.000 description 1
- 239000000021 stimulant Substances 0.000 description 1
- UCRLQOPRDMGYOA-DFTDUNEMSA-L zinc;(4r)-4-[[(2s)-2-[[(4r)-2-[(1s,2s)-1-amino-2-methylbutyl]-4,5-dihydro-1,3-thiazole-4-carbonyl]amino]-4-methylpentanoyl]amino]-5-[[(2s,3s)-1-[[(3s,6r,9s,12r,15s,18r,21s)-3-(2-amino-2-oxoethyl)-18-(3-aminopropyl)-12-benzyl-15-[(2s)-butan-2-yl]-6-(carbox Chemical compound [Zn+2].C1SC([C@@H](N)[C@@H](C)CC)=N[C@@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CCC([O-])=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]1C(=O)N[C@H](CCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2NC=NC=2)C(=O)N[C@H](CC([O-])=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCC1 UCRLQOPRDMGYOA-DFTDUNEMSA-L 0.000 description 1
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
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Abstract
The invention discloses a specific traditional Chinese veterinary oral medicine for treating chronic hog cholera. The specific traditional Chinese veterinary oral medicine is prepared from, by weight, 40-50 parts of flos lonicerae, 40-50 parts of radix scutellariae , 40-50 parts of fructus gardeniae, 35-45 parts of radix isatidis, 30-35 parts of herba taraxaci, 10-15 parts of radix glycyrrhizae, 30-35 parts of fructus forsythiae, 25-30 parts of radix bupleuri, 25-30 parts of herba houttuyniae, 20-25 parts of cortex phellodendri and 15-20 parts of rhizoma coptidis. The specific traditional Chinese veterinary oral medicine based on reasonable formulation has remarkable treatment effect to acute, sub-acute and chronic hog cholera, is free of toxic and side effect, has quick action after being applied, is prepared from raw materials easy to obtain and low in cost, avoids disease recurrence, and accordingly is an ideal drug for treating hog cholera.
Description
Technical field
The present invention relates to the field of Chinese medicines, be exactly a kind of special efficacy Traditional Chinese veterinary medicine oral solution treating chronic swine fever.
Background technology
At present, the use to veterinary drug for the country limits more and more stricter.In " feed medicated premix operating specification " that the Ministry of Agriculture issues, concrete regulation is carried out to 54 use object of class feed medicated premix such as Chlortetracycline premix, Bacitracin Zinc pre-mixing agent, purposes, off-drug period etc..In " veterinary drug disabling inventory ", completely forbid or limit sex hormones, the ZERs etc. such as beta-stimulants class, stilbestrol such as using clenobuterol hydrochloride and there are the 21 class medicines such as the calm class of the hypnosis such as the material of estrogen-like action, chloramphenicol and the itrofurans such as preparation, furazolidone, methaqualone.Comprehensive situation both at home and abroad is seen, the scope of China's disabling veterinary drug also will constantly expand from now on.
Herbal medicine, is new industry in recent years.Briefly, it is simply that be applied to traditional Chinese medical theory with animal.Residue of veterinary drug has become the significant obstacle affecting animal husbandry development.Relevant expert thinks, herbal medicine, owing to will not constitute a threat to food security, incites somebody to action to a great extent progressively substituted chemistry medicine.
It is that one has hyperinfection epidemic disease that swine fever is commonly called as " rinderpest ", is one of Infectious Diseases threatening pig industry, it is characterized in that: acute, changes in septic, organa parenchymatosum's bleeding, downright bad and infarct；Chronic in cellulosic necrotic enteritis, often there are paratyphoid and pasteurellosis secondary in the later stage.
Content of the invention
It is an object of the invention to provide a kind of special efficacy Traditional Chinese veterinary medicine oral solution treating chronic swine fever.
Above-mentioned purpose is realized by below scheme:
A kind of special efficacy Traditional Chinese veterinary medicine oral solution treating chronic swine fever, it is characterised in that: it is to be prepared by the raw material of following weight parts:
Honeysuckle 40-50, root of large-flowered skullcap 40-50, cape jasmine 40-50, isatis root 35-45, dandelion 30-35, Radix Glycyrrhizae 10-15, capsule of weeping forsythia 30-35, radix bupleuri 25-30, cordate houttuynia 25-30, golden cypress 20-25, coptis 15-20.
Described a kind of special efficacy Traditional Chinese veterinary medicine oral solution treating chronic swine fever, it is characterised in that: it is to be prepared by the raw material of following weight parts:
Honeysuckle 40, the root of large-flowered skullcap 40, cape jasmine 40, isatis root the 35th, dandelion 30, Radix Glycyrrhizae 10, the capsule of weeping forsythia the 30th, radix bupleuri 25, cordate houttuynia the 25th, golden cypress 20, the coptis 15.
Described a kind of special efficacy Traditional Chinese veterinary medicine oral solution treating chronic swine fever, it is characterised in that:
Preparation method is:
(1) add water after, coptis powder being broken into meal, add sulfuric acid to pH value about 1, decoct 100-110 minute, the more continuous acid adding holding pH value that adds water decoct 3-5 days, extract is concentrated into magma；Repeated hydrogenation calcium oxide liquid adjusts pH value to stir the static supernatant that takes to about 4, and by ethanol precipitation, takes extraction liquid standby；
(2) honeysuckle, the root of large-flowered skullcap, the capsule of weeping forsythia are mixed, 4 each 150-160 minutes of decocting, extract volatile oil and reclaim decocting liquid；Volatile oil is concentrated into thick standby after need to carrying out the merging of secondary distillation decocting liquid, decocting liquid ethanol precipitates, and takes extraction liquid standby；
(3) more than, medicine is decocted 2-3 time altogether, each 120-130 minute, is concentrated into thick after taking decocting liquid merging；
(4) combining step (1), (2), all liquids of (3) gained, with ethanol precipitation, taking liquid；
(5) gained liquid injects and uses water and volatile oil to every milliliter contained 1-1.2 gram；Boil, cool down, refrigerate, quiescent setting, take and clean precipitation, filter and get final product.
Described a kind of special efficacy Traditional Chinese veterinary medicine oral solution treating chronic swine fever, it is characterised in that: add proper amount of active carbon pyrogen removal and impurity, rear essence filter when step (5) is boiled.
The invention have the benefit that
(1) compatibility of the present invention is reasonable, all has obvious curative effect to acute, subacute and chronic type swine fever, without any side effects, controls difficulty in relapse after healing, and instant effect after medication, medicinal material is easy to get, inexpensive, is the preferable medicine for the treatment of swine fever.
(2) present invention have clearing heat and detoxicating, antibechic, relieving asthma, the curative effect such as antibacterial, antiviral, to the pneumonia being caused by virus, enteritis, etc. all have preferable result for the treatment of, solve the breeding difficulty problem of ill sow, more than 95% is reached to acute and chronic swine fever cure rate, long-term taking can also improve the immunity of organisms of pig, serves prevention effect to swine fever.
Detailed description of the invention
A kind of special efficacy Traditional Chinese veterinary medicine oral solution treating chronic swine fever, it is characterised in that: it is to be prepared by the raw material of following weight parts:
Honeysuckle 40, the root of large-flowered skullcap 40, cape jasmine 40, isatis root the 35th, dandelion 30, Radix Glycyrrhizae 10, the capsule of weeping forsythia the 30th, radix bupleuri 25, cordate houttuynia the 25th, golden cypress 20, the coptis 15.
Preparation method is:
(1) adding water after, coptis powder being broken into meal, adding sulfuric acid to pH value is 1, decocts 100 minutes, more continuous acid adding adds water and keeps pH value to decoct 5 days, and extract is concentrated into magma；Repeated hydrogenation calcium oxide liquid adjusts pH value to stir the static supernatant that takes to 4, and by ethanol precipitation, takes extraction liquid standby；
(2) honeysuckle, the root of large-flowered skullcap, the capsule of weeping forsythia are mixed, decocting 4 times 150 minutes every time, extract volatile oil and reclaim decocting liquid；Volatile oil is concentrated into thick standby after need to carrying out the merging of secondary distillation decocting liquid, decocting liquid ethanol precipitates, and takes extraction liquid standby；
(3) more than, medicine is decocted 3 times altogether, 120 minutes every time, is concentrated into thick after taking decocting liquid merging；
(4) combining step (1), (2), all liquids of (3) gained, with ethanol precipitation, taking liquid；
(5) gained liquid injects and uses water and volatile oil to every milliliter contained 1 gram；Boil, cool down, refrigerate, quiescent setting, take and clean precipitation, filter and get final product.
Proper amount of active carbon pyrogen removal and impurity, rear essence filter is added when step (5) is boiled.
The following is the ill pig Clinical practice the case for this embodiment explanation of certain pig farm, according to statistics, ill pig has 212, wherein, suffer from acute or subacute type swine fever has 83, suffer from chronic type swine fever and have 129, take the present embodiment, taking continuously one week, 2-3 days partial symptoms of medication mitigate or disappear, medication 5-7 days, various aspects symptom is obviously improved or substantially disappears, be in a bad way can take one week more, generally takes continuously two weeks, and ill pig can be cured.
Result shows, the present embodiment all has obvious curative effect to acute, subacute and chronic type swine fever, comprehensive efficient is 96.2%, wherein suffer from acute or subacute type swine fever case have 78 healing for 83,3 effective, 2 invalid, efficient is 97.5%, and suffering from for 129 has 117 healings in chronic type swine fever case, and 6 effectively, 6 invalid, and efficient is 95.3%.
Simultaneously ill pig occurs that after taking the present embodiment scabies secondary infection pneumonia significantly reduces with the head number infecting enteritis, and the death rate is greatly reduced.
Claims (4)
1. the special efficacy Traditional Chinese veterinary medicine oral solution treating chronic swine fever, it is characterised in that: it is to be prepared by the raw material of following weight parts:
Honeysuckle 40-50, root of large-flowered skullcap 40-50, cape jasmine 40-50, isatis root 35-45, dandelion 30-35, Radix Glycyrrhizae 10-15, capsule of weeping forsythia 30-35, radix bupleuri 25-30, cordate houttuynia 25-30, golden cypress 20-25, coptis 15-20.
2. a kind of special efficacy Traditional Chinese veterinary medicine oral solution treating chronic swine fever according to claim 1, it is characterised in that: it is to be prepared by the raw material of following weight parts:
Honeysuckle 40, the root of large-flowered skullcap 40, cape jasmine 40, isatis root the 35th, dandelion 30, Radix Glycyrrhizae 10, the capsule of weeping forsythia the 30th, radix bupleuri 25, cordate houttuynia the 25th, golden cypress 20, the coptis 15.
3. a kind of special efficacy Traditional Chinese veterinary medicine oral solution treating chronic swine fever according to claim 1, it is characterised in that:
Preparation method is:
(1) add water after, coptis powder being broken into meal, add sulfuric acid to pH value about 1, decoct 100-110 minute, the more continuous acid adding holding pH value that adds water decoct 3-5 days, extract is concentrated into magma；Repeated hydrogenation calcium oxide liquid adjusts pH value to stir the static supernatant that takes to about 4, and by ethanol precipitation, takes extraction liquid standby；
(2) honeysuckle, the root of large-flowered skullcap, the capsule of weeping forsythia are mixed, 4 each 150-160 minutes of decocting, extract volatile oil and reclaim decocting liquid；Volatile oil is concentrated into thick standby after need to carrying out the merging of secondary distillation decocting liquid, decocting liquid ethanol precipitates, and takes extraction liquid standby；
(3) more than, medicine is decocted 2-3 time altogether, each 120-130 minute, is concentrated into thick after taking decocting liquid merging；
(4) combining step (1), (2), all liquids of (3) gained, with ethanol precipitation, taking liquid；
(5) gained liquid injects and uses water and volatile oil to every milliliter contained 1-1.2 gram；Boil, cool down, refrigerate, quiescent setting, take and clean precipitation, filter and get final product.
4. a kind of special efficacy Traditional Chinese veterinary medicine oral solution treating chronic swine fever according to claim 3, it is characterised in that: add proper amount of active carbon pyrogen removal and impurity, rear essence filter when step (5) is boiled.
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| CN107890486A (en) * | 2017-12-04 | 2018-04-10 | 甘肃省畜牧兽医研究所 | A kind of Chinese medicine external anti-inflammation formulation and its preparation method and application |
| CN110652543A (en) * | 2019-09-14 | 2020-01-07 | 福建省希望生物科技有限公司 | Preparation method and application of Chinese herbal medicine preparation for treating live pig viral enteritis |
| CN112057517A (en) * | 2020-10-23 | 2020-12-11 | 得利斯集团有限公司 | Traditional Chinese medicine composition for improving survival rate of weaned piglets, preparation method and feeding method |
| CN113244360A (en) * | 2021-05-12 | 2021-08-13 | 四川秋蓝生物科技有限公司 | Method for preventing and controlling viral diseases of sows by using Chinese herbal medicines and pharmaceutical formula |
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Application publication date: 20161005 |