CN106421486A - Veterinary traditional Chinese medicine composition with heat clearing and toxicity removing effects and preparation method thereof - Google Patents
Veterinary traditional Chinese medicine composition with heat clearing and toxicity removing effects and preparation method thereof Download PDFInfo
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
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- A61K36/484—Glycyrrhiza (licorice)
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/78—Saururaceae (Lizard's-tail family)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8964—Anemarrhena
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- A61K2236/30—Extraction of the material
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Abstract
The invention discloses a veterinary traditional Chinese medicine composition with heat clearing and toxicity removing effects. The veterinary traditional Chinese medicine composition is prepared from, by weight, 20-35 parts of isatis roots, 20-35 parts of honeysuckle flowers, 5-10 parts of herba houttuyniae, 10-20 parts of radix scutellariae, 5-10 parts of radix rehmanniae, 5-10 parts of rhizoma phragmitis, 5-9 parts of rhizoma anemarrhenae, 6-10 parts of gypsum, 3-7 parts of radix platycodonis and 10-20 parts of licorice roots. The prepared traditional Chinese medicine composition is mainly used for preventing and treating viral and bacterial diseases of livestock and poultry and has the good effects of clearing heat, resisting inflammations and bacteria, improving the immunity and the like. The traditional Chinese medicine composition has the advantages that the formula compositions supplement one another and have a synergistic effect and is significant in effect, safe, poisonless and good in stability; clinical treatment effect experiments show that the treatment effect is exact, the total effective rate is 100%, the cure rate can reach 80%, and the death rate is low.
Description
Technical field
The present invention relates to field of veterinary, be related specifically to a kind of heat-clearing and detoxifying herb composition for animals, this medical instrument have antipyretic,
Anti-inflammatory, antibacterial, enhance immunity etc. act on.
Background technology
Zoonosis is the class disease that aquaculture is endangered with most serious, it be not only likely to result in animal large quantities of dead and
The loss of animal product, impact people's lives and foreign trade, and some Amphixenosises can also give people class health and bring
Serious threat.The aquaculture of especially modernization, animal feeding high concentration, allocation and transportation are mobile frequently, are more vulnerable to infectious disease
Invasion and attack.Therefore, to zoonotic anti-system and research, always paid attention to by countries in the world.
For bacterium and viral infectious, doctor trained in Western medicine is many to be treated using antibiotic.But antibiotics exists scarce
Point：Commonly using and abusing with antibiotic, easily makes bacterium or virus produce drug resistance；Antibiotics is easily in animal body
Interior accumulation, is accumulated into the human body by livestock products food, makes one body and forms resistance physique, gives people class health and bring potential safety hazard.
Content of the invention
For overcoming the weak point of above-mentioned indication, the invention provides one kind is mainly used in livestock and poultry virus, bacteriosis
Prevention and treatment, have antipyretic, the effect such as anti-inflammatory, antibacterial, enhance immunity heat-clearing and detoxifying herb composition for animals and its
Preparation method.
For realizing the object of the invention, it is achieved through the following technical solutions：
A kind of heat-clearing and detoxifying herb composition for animals, is made up of the raw material of following weight portion：Radix Isatidis 20-35 part, honeysuckle 20-
35 parts, cordate houttuynia 5-10 part, root of large-flowered skullcap 10-20 part, radix rehmanniae recen 5-10 part, reed rhizome 5-10 part, wind-weed 5-9 part, gypsum 6-10 part, tangerine
Stalk 3-7 part, Radix Glycyrrhizae 10-20 part.
Above-mentioned heat-clearing and detoxifying herb composition for animals, is made up of the raw material of following weight portion：Radix Isatidis 20-35 part, gold and silver
Flower 20-35 part, cordate houttuynia 5-10 part, root of large-flowered skullcap 10-20 part, radix rehmanniae recen 5-10 part, reed rhizome 5-10 part, 7 parts of the wind-weed, 8 parts of gypsum, tangerine
5 parts of stalk, Radix Glycyrrhizae 10-20 part.
Preferably, the above-mentioned heat-clearing and detoxifying herb composition for animals of the present invention, is made up of the raw material of following weight portion：Radix Isatidis
25 parts, 25 parts of honeysuckle, 5 parts of cordate houttuynia, 12 parts of the root of large-flowered skullcap, 5 parts of radix rehmanniae recen, 5 parts of reed rhizome, 7 parts of the wind-weed, 8 parts of gypsum, 5 parts of balloonflower root,
15 parts of Radix Glycyrrhizae.
The present invention also provides the preparation method of above-mentioned heat-clearing and detoxifying herb composition for animals, takes plate blue by weight ratio
Root, honeysuckle, cordate houttuynia, the root of large-flowered skullcap, radix rehmanniae recen, reed rhizome, the wind-weed, gypsum, balloonflower root and Radix Glycyrrhizae, pulverize, mix, and make scattered
Agent.
Or, take Radix Isatidis, honeysuckle, cordate houttuynia, the root of large-flowered skullcap, radix rehmanniae recen, reed rhizome, the wind-weed, gypsum, tangerine by weight ratio
Stalk and Radix Glycyrrhizae, by the water of gross weight plus 5-8 times, decoct 2-3 hour, and collecting decoction after decocting twice filters, makes oral liquid.
Or, take Radix Isatidis, honeysuckle, cordate houttuynia, the root of large-flowered skullcap, radix rehmanniae recen, reed rhizome, the wind-weed, gypsum, tangerine by weight ratio
Stalk and Radix Glycyrrhizae, by the water of gross weight plus 5-8 times, decoct 2-3 hour, and collecting decoction after decocting twice filters, concentrates, is dried, plus
Enter suitable auxiliary material, make granule, capsule or tablet.
The present invention is summarized as follows from effect of Chinese medicine：
Radix Isatidis is cold in nature, bitter, the thoughts of returning home, stomach, and active ingredient is mainly alkaloids, organic acid, associativity amino acids
And polysaccharide, have functions that clearing heat and detoxicating, cool blood, profit are swallowed.
Honeysuckle is cold in nature, sweet, return lung, stomach, large intestine channel, rich in volatile oil, also flavonoids, triterpenes and organic acid
Deng having functions that clearing heat and detoxicating, dispelling wind and heat from the body.
Cordate houttuynia cold nature, taste is pungent, return lung warp, containing volatile oil, organic acid etc., there is clearing heat and detoxicating, removing pus and relieving carbuncle, profit
Urinate treating stranguria effect.
The root of large-flowered skullcap is cold in nature, bitter, the thoughts of returning home, liver, stomach, large intestine channel, containing baicalein and scutelloside, has antibiosis and antiviral functions
With antipyretic analgesic and anti-inflammatory effects.
Radix rehmanniae recen is cold in nature, sweet-bitter flavor, the thoughts of returning home, liver and kidney channel, and chemical composition, based on glucoside, has clearing heat and cooling blood, yin-nourishing life
The effect in Tianjin.
Reed rhizome is cold in nature, sweet, attaches to the lung and stomach meridians, and has functions that clearing heat and promoting fluid, antipyretic-antalgic.
The wind-weed is cold in nature, bitter but sweet flavor, return lung, stomach, kidney channel, has functions that clearing heat-fire, nourshing Yin and drynsessmoistening prescription.
Gypsum Great Cold, acrid-sweet flavor, attach to the lung and stomach meridians, have functions that clearing heat-fire, relieving restlessness quench the thirst.
Balloonflower root is mild-natured, bitter is pungent, return lung warp, has functions that to declare lung, sharp pharynx, eliminating the phlegm, apocenosis.
Radix Glycyrrhizae is mild-natured, sweet, returns spleen, stomach, lung, the heart channel of Hang-Shaoyin, has tonifying middle-Jiao and Qi, an expelling phlegm and arresting coughing, removing toxic substances, relieving spasm to stop pain, slow
Effect with the property of medicine.
The Chinese medicine composition of present invention preparation is mainly used in the prevention and treatment of livestock and poultry virus, bacteriosis, has good
Good antipyretic, the effect such as anti-inflammatory, antibacterial, enhance immunity.It is an advantage of the invention that：Formula composition complements each other, and has collaborative
Effect；Effect of the present invention is notable, safety non-toxic, good stability；Clinical effect trial shows, determined curative effect of the present invention, always effectively
Rate 100%, up to more than 80%, the death rate is low for cure rate.
Specific embodiment
For ease of those skilled in the art's the understanding of the present invention, provide following examples that the present invention is done furtherly
Bright, but embodiment is not as limitation of the present invention.
Embodiment 1
Take Radix Isatidis 30g, honeysuckle 35g, cordate houttuynia 5g, root of large-flowered skullcap 12g, radix rehmanniae recen 6g, reed rhizome 8g, wind-weed 5g, gypsum 6g, balloonflower root
3g, Radix Glycyrrhizae 15g, all raw materials are pulverized, sieve, and mix, make powder.
Embodiment 2
Take Radix Isatidis 20g, honeysuckle 35g, cordate houttuynia 5g, root of large-flowered skullcap 10g, radix rehmanniae recen 5g, reed rhizome 10g, wind-weed 7g, gypsum 8g, tangerine
Stalk 5g, Radix Glycyrrhizae 15g, all raw materials are pulverized, sieve, and mix, make powder.
Embodiment 3
Take Radix Isatidis 20g, honeysuckle 20g, cordate houttuynia 10g, root of large-flowered skullcap 18g, radix rehmanniae recen 10g, reed rhizome 5g, wind-weed 7g, gypsum 8g, tangerine
Obstruct 5g, Radix Glycyrrhizae 10g, the water of first time plus 8 times of weight portions, decoct 3h, the water that second adds 5 times of weight portions, decoction 2h, filter,
Merging filtrate, concentrates, makes oral liquid.
Embodiment 4
Take Radix Isatidis 24g, honeysuckle 22g, cordate houttuynia 9g, root of large-flowered skullcap 18g, radix rehmanniae recen 10g, reed rhizome 5g, wind-weed 9g, gypsum 10g, tangerine
Obstruct 7g, Radix Glycyrrhizae 10g, the water of first time plus 8 times of weight portions, decoct 3h, the water that second adds 5 times of weight portions, decoction 2h, filter,
Merging filtrate, concentrates, makes oral liquid.
Embodiment 5
Take Radix Isatidis 25g, honeysuckle 25g, cordate houttuynia 5g, root of large-flowered skullcap 12g, radix rehmanniae recen 5g, reed rhizome 5g, wind-weed 7g, gypsum 8g, balloonflower root
5g, Radix Glycyrrhizae 15g, add the water of 8 times of weight portions for the first time, decoct 3h, the water that second adds 5 times of weight portions, decoct 2h, filtration, close
And filtrate, after concentration, plus pelletize after the mixing of proper starch, dextrin, obtain final product granule.
Embodiment 6
Take Radix Isatidis 28g, honeysuckle 31g, cordate houttuynia 7g, root of large-flowered skullcap 10g, radix rehmanniae recen 6g, reed rhizome 7g, wind-weed 6g, gypsum 7g, balloonflower root
4g, Radix Glycyrrhizae 15g, add the water of 8 times of weight portions for the first time, decoct 3h, the water that second adds 5 times of weight portions, decoct 2h, filtration, close
And filtrate, after concentration, plus pelletize after the mixing of proper starch, dextrin, obtain final product granule.
Embodiment 7
Take Radix Isatidis 25g, honeysuckle 25g, cordate houttuynia 10g, root of large-flowered skullcap 20g, radix rehmanniae recen 5g, reed rhizome 5g, wind-weed 7g, gypsum 8g, tangerine
Obstruct 5g, Radix Glycyrrhizae 20g, the water of first time plus 8 times of weight portions, decoct 3h, the water that second adds 5 times of weight portions, decoction 2h, filter,
Merging filtrate, after concentration, drying, adds appropriate microcrystalline cellulose, after mixing, encapsulated, obtains final product capsule.
Embodiment 8
Take Radix Isatidis 30g, honeysuckle 28g, cordate houttuynia 8g, root of large-flowered skullcap 18g, radix rehmanniae recen 6g, reed rhizome 7g, wind-weed 7g, gypsum 7g, balloonflower root
6g, Radix Glycyrrhizae 20g, add the water of 8 times of weight portions for the first time, decoct 3h, the water that second adds 5 times of weight portions, decoct 2h, filtration, close
And filtrate, after concentration, drying, add appropriate microcrystalline cellulose, after mixing, encapsulated, obtain final product capsule.
Embodiment 9
Take Radix Isatidis 35g, honeysuckle 30g, cordate houttuynia 5g, root of large-flowered skullcap 10g, radix rehmanniae recen 10g, reed rhizome 5g, wind-weed 7g, gypsum 8g, tangerine
Obstruct 5g, Radix Glycyrrhizae 20g, the water of first time plus 8 times of weight portions, decoct 3h, the water that second adds 5 times of weight portions, decoction 2h, filter,
Merging filtrate, concentrates, and is dried, after adding appropriate dextrin, soluble starch to pelletize, compressing tablet, and obtain final product tablet.
In order to show the therapeutic effect of the compound Chinese medicinal preparation of the present invention, clinical observation on the therapeutic effect examination is carried out to medicine of the present invention
Test, the beneficial effect of of the present invention medicine is expanded on further below by way of test example：
（1）Subjects：Weizhi County Jin Huan pig farm, is diagnosed as Du × length × big three of affected pig breeding and respiratory disorder syndrome
First pig 100, average weight is 65kg.Symptom is increased to 41 DEG C about for affected pig body temperature, and appetite significantly reduces or useless exhausted, most
Whole body is rubescent, accelerated breathing, and substantially, indivedual sick pig streams stick nose liquid on a small quantity for cough.
（2）Test method：Affected pig is randomly divided into 3 groups, control group 20, do not use any medicine；Drug control group 20
Head, Fuzheng Jiedu powder, with 0.2% ratio spice, is used in conjunction 3 ~ 5 d, until clinical symptom disappearance；Test group 60, be divided into height, in,
Low three dosage groups, every group 10, every group respectively with the embodiment of the present invention 1 compound Chinese medicinal preparation of 0.2%, 0.5% and 1% ratio
Spice, is used in conjunction 3 ~ 5 d, until clinical symptom disappearance.
（3）Criterion：Clinical symptom disappearance is to cure；Clinical symptoms are obviously improved as effective；Clinical symptoms are not changed into
Invalid.
Cure rate（%）=cure head number/treatment total head number × 100%；
Efficient（%）=（Cure head number+effective head number）/ treat total head number × 100%.
Examination pig clinical symptoms change and death condition, record is observed during being administered.
（4）Result of the test is shown in Table 1：
Chinese medicine composition of the present invention is high and middle dose group reaches 100% to affected pig treated effect, death, low dose group
Efficient reach 95%, but have 1 pig death.The blank control group death rate reaches 25%, dead 2 of drug control group, and the death rate reaches
10%.Test group affected pig after treatment, recover by appetite, and spirit takes a turn for the better, and breathing is normal, and fecaluria turns for the better by and large, body temperature normal 39.4
DEG C, skin tip gradually fades, after medication terminates, all clinical symptom disappearance, and affected pig returns to one's perfect health.Chinese medicine composition of the present invention is described
Preparation has good therapeutic effect to pig breathing with breeding difficulty syndrome, can take the circumstances into consideration to add according to the state of an illness and treatment during treatment
Subtract dosage.
Above-described is only the preferred embodiment of the present invention it is noted that for a person skilled in the art,
Under the premise of without departing from general idea of the present invention, some changes and improvements can also be made, these also should be considered as the present invention's
Protection domain.
Claims (7)
1. a kind of heat-clearing and detoxifying herb composition for animals it is characterised in that：It is made up of the raw material of following weight portion：Radix Isatidis 20-
35 parts, honeysuckle 20-35 part, cordate houttuynia 5-10 part, root of large-flowered skullcap 10-20 part, radix rehmanniae recen 5-10 part, reed rhizome 5-10 part, wind-weed 5-9
Part, gypsum 6-10 part, balloonflower root 3-7 part, Radix Glycyrrhizae 10-20 part.
2. the heat-clearing and detoxifying herb composition for animals according to claims 1 it is characterised in that：Former by following weight portion
Material composition：Radix Isatidis 20-35 part, honeysuckle 20-35 part, cordate houttuynia 5-10 part, root of large-flowered skullcap 10-20 part, radix rehmanniae recen 5-10 part, reed rhizome
5-10 part, 7 parts of the wind-weed, 8 parts of gypsum, 5 parts of balloonflower root, Radix Glycyrrhizae 10-20 part.
3. the heat-clearing and detoxifying herb composition for animals according to claims 1 it is characterised in that：Former by following weight portion
Material composition：25 parts of Radix Isatidis, 25 parts of honeysuckle, 5 parts of cordate houttuynia, 12 parts of the root of large-flowered skullcap, 5 parts of radix rehmanniae recen, 5 parts of reed rhizome, 7 parts of the wind-weed, stone
8 parts of cream, 5 parts of balloonflower root, 15 parts of Radix Glycyrrhizae.
4. the heat-clearing and detoxifying herb composition for animals according to any one of claims 1-3 it is characterised in that：Made
Become any one in powder, oral liquid, granule, capsule, tablet.
5. heat-clearing and detoxifying herb composition for animals any one of claims 1-3 preparation method it is characterised in that：Press
Weight takes Radix Isatidis, honeysuckle, cordate houttuynia, the root of large-flowered skullcap, radix rehmanniae recen, reed rhizome, the wind-weed, gypsum, balloonflower root and Radix Glycyrrhizae, pulverize,
Mix, make powder.
6. heat-clearing and detoxifying herb composition for animals any one of claims 1-3 preparation method it is characterised in that：Press
Weight takes Radix Isatidis, honeysuckle, cordate houttuynia, the root of large-flowered skullcap, radix rehmanniae recen, reed rhizome, the wind-weed, gypsum, balloonflower root and Radix Glycyrrhizae, by gross weight
Amount adds water 5-8 times, decocts 2-3 hour, and collecting decoction after decocting twice filters, makes oral liquid.
7. heat-clearing and detoxifying herb composition for animals any one of claims 1-3 preparation method it is characterised in that：Press
Weight takes Radix Isatidis, honeysuckle, cordate houttuynia, the root of large-flowered skullcap, radix rehmanniae recen, reed rhizome, the wind-weed, gypsum, balloonflower root and Radix Glycyrrhizae, by gross weight
Amount adds water 5-8 times, decocts 2-3 hour, and collecting decoction after decocting twice filters, and concentrates, and dry, pulverize into fine powder, adds suitably
Auxiliary material, makes granule, capsule or tablet.
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| CN201611016936.9A CN106421486A (en) | 2016-11-18 | 2016-11-18 | Veterinary traditional Chinese medicine composition with heat clearing and toxicity removing effects and preparation method thereof |
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| CN201611016936.9A CN106421486A (en) | 2016-11-18 | 2016-11-18 | Veterinary traditional Chinese medicine composition with heat clearing and toxicity removing effects and preparation method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107494939A (en) * | 2017-08-23 | 2017-12-22 | 寿县远航湖羊养殖专业合作社 | A kind of lamb epidemic-prevention fodder of early stage dialysis breast milk |
| CN108853315A (en) * | 2018-08-21 | 2018-11-23 | 无锡正大生物股份有限公司 | A kind of sweet mixture of plate a kind of reed mentioned in ancient books tangerine for animals |
| CN113893302A (en) * | 2021-11-29 | 2022-01-07 | 南京农业大学 | Traditional Chinese medicine composition for preventing and treating respiratory syndrome of livestock and poultry as well as preparation method and application thereof |
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| CN102579779A (en) * | 2012-03-22 | 2012-07-18 | 郭耀亭 | Chinese medicinal composition, Chinese medicinal preparation and feed for treating and/or preventing respiratory system diseases of livestock |
| CN105169012A (en) * | 2015-08-28 | 2015-12-23 | 徐州天意动物药业有限公司 | Antivirus traditional Chinese medicine composition for livestock and poultry, fermented traditional Chinese medicine and preparation method and application |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102579779A (en) * | 2012-03-22 | 2012-07-18 | 郭耀亭 | Chinese medicinal composition, Chinese medicinal preparation and feed for treating and/or preventing respiratory system diseases of livestock |
| CN105169012A (en) * | 2015-08-28 | 2015-12-23 | 徐州天意动物药业有限公司 | Antivirus traditional Chinese medicine composition for livestock and poultry, fermented traditional Chinese medicine and preparation method and application |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107494939A (en) * | 2017-08-23 | 2017-12-22 | 寿县远航湖羊养殖专业合作社 | A kind of lamb epidemic-prevention fodder of early stage dialysis breast milk |
| CN108853315A (en) * | 2018-08-21 | 2018-11-23 | 无锡正大生物股份有限公司 | A kind of sweet mixture of plate a kind of reed mentioned in ancient books tangerine for animals |
| CN113893302A (en) * | 2021-11-29 | 2022-01-07 | 南京农业大学 | Traditional Chinese medicine composition for preventing and treating respiratory syndrome of livestock and poultry as well as preparation method and application thereof |
| CN113893302B (en) * | 2021-11-29 | 2022-05-24 | 南京农业大学 | Traditional Chinese medicine composition for preventing and treating respiratory syndrome of livestock and poultry as well as preparation method and application thereof |
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