CN104173977A - Traditional Chinese medicine composition for stopping rhinorrhea, clearing heat and relieving fidgetiness in common cold and preparation method of traditional Chinese medicine composition - Google Patents
Traditional Chinese medicine composition for stopping rhinorrhea, clearing heat and relieving fidgetiness in common cold and preparation method of traditional Chinese medicine composition Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for stopping rhinorrhea, clearing heat and relieving fidgetiness in a common cold and a preparation method of the traditional Chinese medicine composition. The composition is mainly prepared from the following raw medicinal materials in parts by weight: 3 to 9 parts of ephedra, 12 to 16 parts of raw gypsum, 3 to 7 parts of Japanese peristrophe herb, 6 to 15 parts of toasted almond, 18 to 25 parts of Chinese yam, 6 to 12 parts of mint, 9 to 15 parts of radix ophiopogonis, 4 to 9 parts of pigeonpea root, 6 to 12 parts of honeysuckle, 4 to 9 parts of rhizoma anemarrhenae, 5 to 15 parts of radix angelicae, 3 to 9 parts of honey-fried licorice root, 2 to 6 parts of fresh ginger, 6 to 12 parts of Chinese dates, 5 to 15 parts of perilla leaves, 3 to 12 parts of platycodon grandiflorum, 9 to 16 parts of common hogfenneI root, 9 to 13 parts of burdock, 4 to 6 parts of graperoot and 6 to 12 parts of herba schizonepetae. The composition disclosed by the invention is scientific in formula, synergetic in action, convenient to take and obvious in effect.
Description
Technical field
The invention discloses a kind of Chinese medicine preparation, especially for Chinese medicine composition and the preparation method of flu watery nasal discharge clearing heat and relieving fidgetness.Belong to Chinese medicine field.
Background technology
Flu is the common exogenous diseases due to a kind of ailment said due to cold or exposure invasion and attack human body.It is its feature that nasal obstruction, cough, headache, fever with aversion to cold, general malaise are take in clinical manifestation.All can fall ill the whole year, especially common with spring.Because evil different, the physical strength of sense differs, syndrome can show as wind and cold, the large class of wind heat two, and has the accompanied symptoms that folder is wet, press from both sides summer-heat, and the difference of weakness type cold.The generation of flu is empty mainly due to body, and resistance against diseases weakens, and when weather drastic change, human body is defended external work and can be adapted to, and pathogen is taken advantage of a weak point in opponent's defence by fur, mouth and nose and people, causes that a series of lungs defend symptom.Partially cold person, causes pathogenic cold hampering the exterior, inhibited pulmonary QI, yang-energy: strongly fragrant resistance, occlusion of the pores of skin; Partial heat person, the pathogenic heat lung that burns, space between skin and muscles catharsis, impairment of purifying function of the lung.Though it is common with ailment said due to cold or exposure to catch a cold, different with season, press from both sides seasonal epidemic pathogens or gas when non-more, as press from both sides wet, folder summer-heat etc.Primary symptom fever with aversion to cold, headache, nasal obstruction watery nasal discharge, floating pulse.Doublely see aversion to cold weight, heating gently or is not generated heat, and lossless, rhinocnesmus sneeze, has a stuffy nose low voice speaking, coughs up clear and thin sputum, and limbs are miserable, white and thin fur, and floating and tense pulse, is anemofrigid cold; Micro evil wind is cold, and heating is heavy, has antiperspirant, and the turbid tears of having a stuffy nose, cough up phlegm thick or yellow, and laryngopharynx swelling and pain is thirsty, yellow and thin fur, and floating and rapid pulse, is anemopyretic cold; The wet headache of folder is as wrapped up in, uncomfortable in chest indigestion and loss of appetite; Folder summer-heat is no relieving of symptom after perspiration, restlessness and thirst.
Simple viral infection is without being used antibacterials, has numeration of leukocyte risings, pharyngeal pus tongue, while coughing the antibacterial infection evidences such as yellow sputum, can use as one sees fit penicillin, first generation cephalosporin, Macrolide or quinolones.Seldom need to select responsive antibacterials according to pathogen.In traditional Chinese medical herbal treatment, the Chinese medicine with heat-clearing and toxic substances removing and antivirus action also can be selected, and contributes to improve symptom, shortens the course of disease.Publication number CN 102526578 A(application numbers 201210013656.8) Chinese patent literature discloses a kind of granular medicine for the treatment of flu, this Chinese medicine granules adopts Radix Bupleuri, Flos Lonicerae, Herba Schizonepetae, Folium Perillae, Folium Isatidis, Pericarpium Citri Reticulatae, Bulbus Fritillariae Cirrhosae, Rhizoma Chuanxiong, Radix Glehniae, Flos Magnoliae, Herba Taraxaci, Radix Puerariae, Semen Coicis, the Radix Astragali, Radix Glycyrrhizae, Poria, Radix Ophiopogonis, Rhizoma Et Radix Notopterygii, Flos Chrysanthemi, Fructus Tritici Levis, Semen Nelumbinis, the Radix Angelicae Dahuricae, Fructus Mume, Rhizoma Alpiniae Officinarum, stir-fried kidney beans, Bulbus Lilii is raw material, add required various conventional adjuvant, as thickening agent, sweeting agent, with conventional method of Chinese medicinal, be prepared into conventional granular preparation.Publication number CN 102526199 A(application numbers 201210085639.5) Chinese patent literature discloses a kind of Wind-cold influenza capsule, medicated powder in capsule is Herba Ephedrae 0.5-1.8 part by weight, Ramulus Cinnamomi 0.5-1.8 part, the compositions that Radix Saposhnikoviae 0.8-3.6 part and the former medicine of Herba Schizonepetae 0.8-2.5 part or decoction pieces mix, in compositions, can also add Rhizoma Et Radix Notopterygii 1-2.5 part, Radix Angelicae Pubescentis 1-2.5 part, Radix Angelicae Dahuricae 0.5-2.6 part, Flos Farfarae 0.8-2.5 part, Semen Armeniacae Amarum 0.8-1.8 part, Bulbus Lilii 1-2.5 part, Radix Stemonae 0.8-2.6 part, Herba Asari 0.1-0.3 part, Radix Glycyrrhizae 0.5-1.8 part.Publication number CN 102145114 A(application numbers 201110082635.7) Chinese patent literature discloses a kind of Chinese medicine of novel therapeutic flu, the preparation method of its invention is to get 100 grams of Herba Schizonepetae, 100 grams of Radix Saposhnikoviaes, 100 grams, the Radix Rehmanniae, 60 grams of Flos Magnoliae, 100 grams of Fructus Arctiis, 100 grams of Radix Scutellariaes, 150 grams of Flos Loniceraes, 100 grams of Rhizoma Belamcandae, 300 grams of Radix Isatidiss, 100 grams of Radix Platycodoniss, 100 grams of Radix Peucedanis, 100 grams of Flos Farfaraees, 30 grams of Periostracum Cicadaes, 60 grams, Radix Glycyrrhizae, 50 grams of Radix Bupleuri, 40 grams, Semen Armeniacae Amarum, 50 grams of Bulbus Fritillariae Cirrhosaes are mixed into sieve, the punching of clear water sieve, pull oven dry out, pulverize, machine is made ball.
In a word, Chinese medicine is being obtained good curative effect in treatment aspect primary disease, but because Chinese medicine preparation mostly now is thick purificant, wherein effective ingredient is still not clear, the medical material curative effect of arranging in pairs or groups in part Chinese prescription is not fine, and treatment by Chinese herbs flu is to be further improved in addition.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide Chinese medicine composition and the preparation method of the flu watery nasal discharge clearing heat and relieving fidgetness of a kind for the treatment of both the principal and secondary aspects of a disease, taking convenience, shortening healing time.This Chinese medicine preparation selected materials all has no side effect, and collocation rationally.
Technical scheme of the present invention is:
Flu watery nasal discharge clearing heat and relieving fidgetness Chinese medicine composition, is prepared from by following main materials medicine, is weight portion: Herba Ephedrae 3-9, Gypsum Fibrosum 12-16, Herba Peristrophes 3-7, stir-baked SEMEN ARMENIACAE AMARUM 6-15, Rhizoma Dioscoreae 18-25, Herba Menthae 6-12, Radix Ophiopogonis 9-15, Semen Cajani root 4-9, Flos Lonicerae 6-12, Rhizoma Anemarrhenae 4-9, Radix Angelicae Dahuricae 5-15, Radix Glycyrrhizae Preparata 3-9, Rhizoma Zingiberis Recens 2-6, Fructus Jujubae 6-12, Folium Perillae 5-15, Radix Platycodonis 3-12, Radix Peucedani 9-16, Fructus Arctii 9-13, graperoot 4-6, Herba Schizonepetae 6-12(is preferred, Herba Schizonepetae 8.5-10; Be more preferably Herba Schizonepetae 9.5).
In preferred version: Herba Ephedrae 5-7, Gypsum Fibrosum 13-15, Herba Peristrophes 4-6, stir-baked SEMEN ARMENIACAE AMARUM 9-12, Rhizoma Dioscoreae 20-23, Herba Menthae 8-10, Radix Ophiopogonis 11-13, Semen Cajani root 6-8, Flos Lonicerae 8-10, Rhizoma Anemarrhenae 5-7, Radix Angelicae Dahuricae 9-11, Radix Glycyrrhizae Preparata 5-7, Rhizoma Zingiberis Recens 3-5, Fructus Jujubae 8-10, Folium Perillae 9-11, Radix Platycodonis 6-8, Radix Peucedani 12-14, Fructus Arctii 10-12, graperoot 4-6, Herba Schizonepetae 8-10.
Preferred scheme is: Herba Ephedrae 6, Gypsum Fibrosum 14, Herba Peristrophes 5, stir-baked SEMEN ARMENIACAE AMARUM 10.5, Rhizoma Dioscoreae 21.5, Herba Menthae 9, Radix Ophiopogonis 12, Semen Cajani root 7, Flos Lonicerae 9, the Rhizoma Anemarrhenae 6, the Radix Angelicae Dahuricae 10, Radix Glycyrrhizae Preparata 6, Rhizoma Zingiberis Recens 4, Fructus Jujubae 9, Folium Perillae 10, Radix Platycodonis 7, Radix Peucedani 13, Fructus Arctii 11, graperoot 5, Herba Schizonepetae 9.
The present invention also provides the preparation method of above-mentioned Chinese medicine composition being made to pharmaceutically acceptable decoction, pill and granule.
The preparation method of described decoction is:
(1) Gypsum Fibrosum is smashed, soaked 30 minutes, then intense fire is fried open, and turns 40 minutes at a simmer, filtering medicinal liquid, and recrement is watered and decocts, and mixes gained medicinal liquid twice;
(2) by Herba Ephedrae, stir-baked SEMEN ARMENIACAE AMARUM, Rhizoma Dioscoreae, Radix Ophiopogonis, Semen Cajani root, the Rhizoma Anemarrhenae, Rhizoma Zingiberis Recens, Fructus Jujubae, Radix Platycodonis, Radix Peucedani, Fructus Arctii, graperoot dedusting roguing, put into marmite intense fire and decoct to boiling, turn 30 minutes at a simmer, filtering medicinal liquid, recrement is watered and decocts, and mixes gained medicinal liquid twice;
(3), by Herba Peristrophes, Herba Menthae, Flos Lonicerae, the Radix Angelicae Dahuricae, Radix Glycyrrhizae Preparata, Folium Perillae, Herba Schizonepetae dedusting roguing, airtight decoction 20 minutes, repeats twice, mixes gained medicinal liquid;
(4) by decoct for above-mentioned three times medicinal liquid mix, sterile packaged, obtains the decoction of Chinese medicine composition.
The preparation method of described pill is:
(1) each crude drug is ground into fine powder, excessively after 80 mesh sieves, mixes;
(2) medicated powder is placed in the container of dried and clean, adds proper honey, even agglomerate is made in kneading in addition;
(3) rubbing pill after placement a period of time, after its dry tack free, with the standard pack of 4g/ ball, obtains the pill of Chinese medicine composition.
The preparation method of described granule is:
(1) by gained Chinese medicine composition decoction, carry out centrifugalize, remove tiny medicinal residues;
(2) under 1.33kPa lower pressure environment, medicinal liquid is heated and concentrate, the time is 40 minutes;
(3) add again a certain proportion of sucrose and ethanol to mix with medicinal liquid, dry and be compressed into tablet;
(4) tablet is pulverized again, every 4g/ wraps, and obtains the granule of Chinese medicine composition.
The preparation method of described Chinese medicinal composition granules, step (2) heats medicinal liquid concentrated under 1.33kPa lower pressure environment, makes it become the thick paste that relative density is 1.30-1.35.
The preparation method of described Chinese medicinal composition granules, step (3) is mixed thick paste, sucrose, ethanol according to the ratio of 1.5:1:1-2.5:1:1 (being preferably 2:1:1).
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Herba Ephedrae: nature and flavor: pungent, micro-hardship, temperature.Return lung, urinary bladder channel.There is diaphoresis cold expelling, depressed lung-energy dispersing, the effect of inducing diuresis to remove edema.For anemofrigid cold, uncomfortable in chest breathing with cough, edema due to wind pathogen edema.Honey Herba Ephedrae nourishing the lung to arrest cough, is used for exterior syndrome and separates, asthma and cough.
Gypsum Fibrosum: Gypsum Fibrosum is monoclinic system mineral, main chemical compositions is calcium sulfate (CaSO
4) hydrate.Gypsum Fibrosum is natural dihydrate gypsum (CaSO both
42H
2o).Nature and flavor: pungent, sweet, be slightly cold.Attach to the lung and stomach meridians.Have clearing away heat-fire, relieving restlessness is quenched the thirst, the effect of convergence granulation promoting.Cure mainly: apoplexy cold and heat, heart subinverse gas is frightened to be breathed heavily, and xerostomia scorching tongue, can not cease, hardness and fullness in the abdomen pain, evil removing ghost, puerperium incised wound.Except seasonal epidemic pathogens headache fever of the body, the large heat of three warmers, skin heat, stagnation of QI in the intestines and stomach, expelling pathogenic factors from muscles by diaphoresis, the restlessness accompanied by ascending of QI of only quenching one's thirst, the sudden and violent gas of abdominal distention, the pharynx heat of panting, also can do bath soup.Cure the wound cold headache as split.Simmer tea with Herba Alii fistulosi, the pain of decaptitating.Control day row fanatic, wind syndrome of head revolves, and stimulating milk secretion is wiped tooth benefit tooth.Except gastric heat lung-heat, loose YIN pathogen, slow spleen QI invigorating.Stop Yangming Channel headache, fever with chills, day food in one's mouth hectic fever, drinking a large amount of water due to extreme thirst, heatstroke hectic fever, has a toothache.
Herba Peristrophes: be the herb of Acanthaceae Herba Peristrophes platymiscium Herba Peristrophes., composition: aerial parts contains the black alcohols of plant: lupeol, stigmasterol, cupreol glucosides, cupreol glucoside.Pharmacology: antibacterial action Herba Peristrophes has stronger inhibitory action to staphylococcus aureus, Hemolytic streptococcus, the false single bacteria of Aerugo, klebsiella pneumoniae.The property of medicine: pungent, cool.Function cures mainly: expelling wind and clearing away heat, cool liver arresting convulsion, removing toxic substances and promoting subsidence of swelling.Cure mainly cold, fever, lung-heat cough with asthma, liver-heat conjunctival congestion, infantile convulsion, laryngopharynx swelling and pain, toxic swelling, hemorrhoid, snake bite and insect sting, traumatic injury.
Semen Armeniacae Amarum: base is former: be the dry seed of the bitter in the mouth such as rosaceous plant Fructus Pruni or Prunus armeniaca L.var.ansu Maxim..Composition: containing amygdalin approximately 3%, fatty oil (almond oil) approximately 50%, protein and various free amino acid.Nature and flavor: hardship, temperature, poisonous.Enter lung, large intestine channel.There is expelling phlegm for arresting cough, relieving asthma, the effect of intestine moistening.Be used for controlling exogenous cough, dyspnea with fullness of the chest, sore throat, dryness of the intestine constipation.Concoct: Semen Armeniacae Amarum: choose clean impurity, put in boiling water and slightly boil, the Pi Wei that waits purses up and pulls out, soaks in cold water, sloughs kind of a skin, dries, winnow with a dustpan clean.Stir-baked SEMEN ARMENIACAE AMARUM: get clean Semen Armeniacae Amarum and put in pot and fry to micro-yellow with slow fire, taking-up cools.
Rhizoma Dioscoreae: nature and flavor: sweet, flat.Return spleen, lung, kidney channel.There is spleen reinforcing nourishing the stomach, the lung benefiting that promotes the production of body fluid, the effect of the kidney invigorating arresting seminal emission.For insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney, and leukorrhagia, frequent micturition, deficiency-heat is quenched one's thirst.Rhizoma Dioscoreae (parched with bran) spleen reinforcing stomach invigorating.For insufficiency of the spleen lack of appetite, the loose stool of having loose bowels, leukorrhagia.
Herba Menthae: acrid in the mouth, cool in nature.There is dispelling wind and heat pathogens, the clear sharp head, sore-throat relieving rash, the effect of soothing the liver circulation of qi promoting, for laryngopharynx swelling and pain, headache, stagnation of QI due to depression of the liver.
Radix Ophiopogonis: nature and flavor: sweet, micro-hardship, is slightly cold.Gui Jing: GUIXIN, lung, stomach warp.Effect: YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire.Cure mainly: for dryness of the lung dry cough.Chronic consumptive disease cough, Tianjin wound is thirsty, vexed insomnia, interior-heat is quenched one's thirst, dryness of the intestine constipation; Pharyngeal diphtheria.
Semen Cajani root: base is former: be the root of pulse family Semen Cajani platymiscium Semen Cajani.The property of medicine: hardship, cold.Function cures mainly: heat-clearing and toxic substances removing, dampness removing, hemostasis.Cure mainly laryngopharynx swelling and pain, ulcer sore pain, bleeding hemorrhoids, stranguria with blood, edema, dysuria.
Flos Lonicerae: sweet in the mouth, micro-hardship, cold nature., have heat-clearing and toxic substances removing, expelling pathogenic factors from the exterior is gone out, the effect of stomach function regulating preventing or arresting vomiting is stopped up resistance, disorder of stomach-QI, fever and irritability for pathogenic heat.
The Rhizoma Anemarrhenae: nature and flavor: bitter, sweet, cold.Return lung, stomach, kidney channel.There is clearing away heat-fire, nourshing Yin and drynsessmoistening prescription effect.For fever caused by exogenous pathogenic factors, high hot excessive thirst, lung-heat type cough, osteopyrexia and fever, interior-heat is quenched one's thirst, dryness of the intestine constipation.
The Radix Angelicae Dahuricae: acrid in the mouth, warm in nature.For inducing sweat, medicine dispels the wind.There is expelling wind and removing dampness, understand things pain-stopping, the effect of detumescence and apocenosis, for the headache of catching a cold, nasal obstruction, nasal sinusitis.
Radix Glycyrrhizae Preparata: nature and flavor: sweet, flat.GUIXIN, lung, spleen, stomach warp.There is spleen reinforcing stomach function regulating, the effect of Yiqi and vein recovery.For weakness of the spleen and stomach, fatigue and weakness, severe palpitation, irregularly intermittent and regularly intermittent pulse.
Rhizoma Zingiberis Recens: nature and flavor: pungent, tepor.Return lung, spleen, stomach warp.There is the cold expelling of inducing sweat, warming middle-JIAO to arrest vomiting, preventing phlegm from forming and stopping coughing, the effect of solving toxin of fish and crab.For anemofrigid cold, gastrofrigid vomiting, cold-phlegm cough, fish Eriocheir sinensis is poisoning.
Fructus Jujubae: nature and flavor: sweet, temperature.Return spleen, stomach, heart channel.There is invigorating the spleen and replenishing QI, the effect of nourishing blood to tranquillize the mind.For insufficiency of the spleen lack of appetite, weak loose stool, woman hysteria.
Folium Perillae: nature and flavor: pungent, temperature.Return lung, spleen channel.There is the cold expelling of inducing sweat, the effect of relieving QI stagnancy in the stomach.For anemofrigid cold, cough vomiting and nausea, vomiting during pregnancy, fish Eriocheir sinensis is poisoning.
Radix Platycodonis: nature and flavor: bitter, pungent, flat.Gui Jing: return lung meridian.Effect: lung qi dispersing, sore-throat relieving, eliminates the phlegm, evacuation of pus.Cure mainly: for cough with copious phlegm, uncomfortable in chest not smooth, pharyngalgia, hoarseness, lung abscess vomiting pus, skin infection difficulty in discharging of pus.
Radix Peucedani: nature and flavor: bitter, pungent, be slightly cold.Return lung meridian.There is lowering the adverse-rising QI to resolve phlegm, the effect of loose wind heat clearing away.Full for expectorant dyspnea of heat type, cough up phlegm yellow thick. cough due to pathogenic wind-heat's abundant expectoration.
Fructus Arctii: nature and flavor: pungent, bitter, cold.Attach to the lung and stomach meridians.There is dispelling wind and heat pathogens, lung qi dispersing rash, the effect of resolving toxin and disinhibiting the throat.For anemopyretic cold, cough with copious phlegm, measles, rubella, laryngopharynx swelling and pain, mumps, erysipelas, carbuncle sore tumefacting virus.
Graperoot: base is former: be the root of Berberidaceae Mahonia fortunei (Lindl.) Fedde platymiscium Mahonia bealei (Fort.) Carr., mahonia fortuneiFedde.Composition: 1. Mahonia bealei (Fort.) Carr. root contains alkaloid: berberine.2. south China graperoot contains alkaloid: isotetrandrine, berberine, palmatine, jateorhizine and berbamine.The property of medicine: < < Traditional Chinese Medicine in Sichuan will > > nineteen sixty version: " cold in nature, bitter in the mouth." function cures mainly: heat clearing and damp drying, removing toxic substances and promoting subsidence of swelling.Cure mainly hygropyretic dysentery, diarrhoea, jaundice, pulmonary tuberculosis hemoptysis, throat pain, toothache, conjunctival congestion and swelling pain, traumatic injury, skin infection, eczema, scalds etc.Compatibility and incompatibility of drugs: the careful clothes of Deficiency and coldness of spleen and stomach person.
Herba Schizonepetae: nature and flavor: pungent, tepor.Return lung, Liver Channel.There is the loose wind that induces sweat, rash, the effect of the skin ulcer that disappears.For flu, headache, measles, rubella, skin infection from the beginning of.
Flu watery nasal discharge clearing heat and relieving fidgetness Chinese medicine composition prescription science provided by the invention, effect are worked in coordination with, and products obtained therefrom is conveniently taken, successful.In addition, excellent results of the present invention also shows:
1
,this Chinese medicine preparation be take flu watery nasal discharge clearing heat and relieving fidgetness as primary treatment direction, with strong points, effective;
2
,the selected crude drug of this prescription is and has no side effect, and is applicable to all ages and classes section people and takes;
3
,this Chinese drug-treated group is mood gently, improves body immunity.
The specific embodiment
Below in conjunction with embodiment and test example, describe technical scheme of the present invention in detail, but protection domain is not limited to this.
embodiment 1flu watery nasal discharge clearing heat and relieving fidgetness Chinese medicine composition, is prepared from by following main materials medicine: Herba Ephedrae 3g, Gypsum Fibrosum 12g, Herba Peristrophes 3g, stir-baked SEMEN ARMENIACAE AMARUM 6g, Rhizoma Dioscoreae 18g, Herba Menthae 6g, Radix Ophiopogonis 9g, Semen Cajani root 4g, Flos Lonicerae 6g, Rhizoma Anemarrhenae 4g, Radix Angelicae Dahuricae 5g, Radix Glycyrrhizae Preparata 3g, Rhizoma Zingiberis Recens 2g, Fructus Jujubae 6g, Folium Perillae 5g, Radix Platycodonis 3g, Radix Peucedani 9g, Fructus Arctii 9g, graperoot 4g, Herba Schizonepetae 6g.The preparation method of described decoction is:
(1) Gypsum Fibrosum is smashed, soaked 30 minutes, then intense fire is fried open, and turns 40 minutes at a simmer, filtering medicinal liquid, and recrement is watered and decocts, and mixes gained medicinal liquid twice;
(2) by Herba Ephedrae, stir-baked SEMEN ARMENIACAE AMARUM, Rhizoma Dioscoreae, Radix Ophiopogonis, Semen Cajani root, the Rhizoma Anemarrhenae, Rhizoma Zingiberis Recens, Fructus Jujubae, Radix Platycodonis, Radix Peucedani, Fructus Arctii, graperoot dedusting roguing, put into marmite intense fire and decoct to boiling, turn 30 minutes at a simmer, filtering medicinal liquid, recrement is watered and decocts, and mixes gained medicinal liquid twice;
(3), by Herba Peristrophes, Herba Menthae, Flos Lonicerae, the Radix Angelicae Dahuricae, Radix Glycyrrhizae Preparata, Folium Perillae, Herba Schizonepetae dedusting roguing, airtight decoction 20 minutes, repeats twice, mixes gained medicinal liquid;
(4) by decoct for above-mentioned three times medicinal liquid mix, sterile packaged, obtains the decoction of Chinese medicine composition.
The instructions of taking of decoction of the present invention: 7 days courses for the treatment of, taken three times a day, a 250ml.
Model case: xxx, the age: 60 years old; Sex: male; Main suit: heating, cough and be admitted to hospital for two days; History of present illness: catch a cold two weeks, still have a fever, nasal obstruction watery nasal discharge, cough, itching throat and pain, be hard and dry, and urine is normal, the micro-number of floating pulse, pale tongue with white fur Huang is greasy; Diagnosis: flu folder is wet.
Take the decoction of this example gained, taken three times a day, a 250ml, seven days courses for the treatment of.Take 7 days, heating paresthesia disappears, and nasal obstruction watery nasal discharge cough phenomenon alleviates, and continues to take a course for the treatment of, without other malaise symptoms, and patient's recovery from illness.
embodiment 2flu watery nasal discharge clearing heat and relieving fidgetness Chinese medicine composition, is prepared from by following main materials medicine: Herba Ephedrae 9g, Gypsum Fibrosum 16g, Herba Peristrophes 7g, stir-baked SEMEN ARMENIACAE AMARUM 15g, Rhizoma Dioscoreae 25g, Herba Menthae 12g, Radix Ophiopogonis 15g, Semen Cajani root 9g, Flos Lonicerae 12g, Rhizoma Anemarrhenae 9g, Radix Angelicae Dahuricae 15g, Radix Glycyrrhizae Preparata 9g, Rhizoma Zingiberis Recens 6g, Fructus Jujubae 12g, Folium Perillae 15g, Radix Platycodonis 12g, Radix Peucedani 16g, Fructus Arctii 13g, graperoot 6g, Herba Schizonepetae 12g.The preparation method of described pill is:
(1) each crude drug is ground into fine powder, excessively after 80 mesh sieves, mixes;
(2) medicated powder is placed in the container of dried and clean, adds proper honey, even agglomerate is made in kneading in addition;
(3) rubbing pill after placement a period of time, after its dry tack free, with the standard pack of 4g/ ball, obtains the pill of Chinese medicine composition.
Pill instructions of taking of the present invention: each ball, three times on the one, warm boiled water, seven days is a course for the treatment of.
embodiment 3flu watery nasal discharge clearing heat and relieving fidgetness Chinese medicine composition, is prepared from by following main materials medicine: Herba Ephedrae 5g, Gypsum Fibrosum 13g, Herba Peristrophes 4g, stir-baked SEMEN ARMENIACAE AMARUM 9g, Rhizoma Dioscoreae 20g, Herba Menthae 8g, Radix Ophiopogonis 11g, Semen Cajani root 6g, Flos Lonicerae 8g, Rhizoma Anemarrhenae 5g, Radix Angelicae Dahuricae 9g, Radix Glycyrrhizae Preparata 5g, Rhizoma Zingiberis Recens 3g, Fructus Jujubae 8g, Folium Perillae 9g, Radix Platycodonis 6g, Radix Peucedani 12g, Fructus Arctii 10g, graperoot 4g, Herba Schizonepetae 8g.
The preparation method of described granule is:
(1) by gained Chinese medicine composition decoction, carry out centrifugalize, remove tiny medicinal residues;
(2) medicinal liquid is heated under 1.33kPa lower pressure environment and concentrate, make it become the thick paste that relative density is 1.30-1.35;
(3) thick paste, sucrose, ethanol are mixed according to the ratio of 2:1:1, dry and be compressed into tablet;
(4) tablet is pulverized again, every 4g/ wraps, and obtains the granule of Chinese medicine composition.
The instructions of taking of granule of the present invention: each bag, three times on the one, warm boiled water, seven days is a course for the treatment of.
embodiment 4flu watery nasal discharge clearing heat and relieving fidgetness Chinese medicine composition, is prepared from by following main materials medicine: Herba Ephedrae 7g, Gypsum Fibrosum 15g, Herba Peristrophes 6g, stir-baked SEMEN ARMENIACAE AMARUM 12g, Rhizoma Dioscoreae 23g, Herba Menthae 10g, Radix Ophiopogonis 13g, Semen Cajani root 8g, Flos Lonicerae 10g, Rhizoma Anemarrhenae 7g, Radix Angelicae Dahuricae 11g, Radix Glycyrrhizae Preparata 7g, Rhizoma Zingiberis Recens 5g, Fructus Jujubae 10g, Folium Perillae 11g, Radix Platycodonis 8g, Radix Peucedani 14g, Fructus Arctii 12g, graperoot 6g, Herba Schizonepetae 10g.
The preparation method of described pill is:
(1) each crude drug is ground into fine powder, excessively after 80 mesh sieves, mixes;
(2) medicated powder is placed in the container of dried and clean, adds proper honey, even agglomerate is made in kneading in addition;
(3) rubbing pill after placement a period of time, after its dry tack free, with the standard pack of 4g/ ball, obtains the pill of Chinese medicine composition.
Pill instructions of taking of the present invention: each ball, three times on the one, warm boiled water, seven days is a course for the treatment of.
Model case: xxx, the age: 30 years old; Sex: male; Main suit: nasal obstruction, watery nasal discharge 4 days, heating, aversion to cold, headache 2 days.Medical history: when working February 4 because of the change in weather sense that wears very little clothes cold, self-induction aversion to cold, stuffy nose with watery discharge, slightly coughs, sneeze, headache, because being busy with one's work, does not mind.Played fever and sweating yesterday, slight chill, distending pain in the head, the turbid tears of nasal obstruction stream, thirst and liking drink, has sore throat, and yellow thick expectorant, yellow urine are coughed up in cough.Auxiliary examination: 39.8 ° of C of body temperature.Pharyngeal congestion, the enlargement of tonsil II degree, no pus point.Tongue fur BOHUANG, floating and rapid pulse.Diagnosis: common cold due to wind heat.
Take the pill of this example gained, three times on the one, each ball, warm boiled water, seven days is a course for the treatment of.Take after seven days, nasal obstruction watery nasal discharge, fever with chills phenomenon obviously alleviate, and breathe smooth and easyly, and expectoration amount also greatly reduces, and continues to take a course for the treatment of, and spirit strengthens, health recovery from illness.
embodiment 5flu watery nasal discharge clearing heat and relieving fidgetness Chinese medicine composition, is prepared from by following main materials medicine: Herba Ephedrae 6g, Gypsum Fibrosum 14g, Herba Peristrophes 5g, stir-baked SEMEN ARMENIACAE AMARUM 10.5g, Rhizoma Dioscoreae 21.5g, Herba Menthae 9g, Radix Ophiopogonis 12g, Semen Cajani root 7g, Flos Lonicerae 9g, Rhizoma Anemarrhenae 6g, Radix Angelicae Dahuricae 10g, Radix Glycyrrhizae Preparata 6g, Rhizoma Zingiberis Recens 4g, Fructus Jujubae 9g, Folium Perillae 10g, Radix Platycodonis 7g, Radix Peucedani 13g, Fructus Arctii 11g, graperoot 5g, Herba Schizonepetae 9g.
The preparation method of described granule is:
(1) by gained Chinese medicine composition decoction, carry out centrifugalize, remove tiny medicinal residues;
(2) medicinal liquid is heated under 1.33kPa lower pressure environment and concentrate, make it become the thick paste that relative density is 1.30-1.35;
(3) thick paste, sucrose, ethanol are mixed according to the ratio of 2:1:1, dry and be compressed into tablet;
(4) tablet is pulverized again, every 4g/ wraps, and obtains the granule of Chinese medicine composition.
The instructions of taking of granule of the present invention: each bag, three times on the one, warm boiled water, seven days is a course for the treatment of.
test example 1the clinical practice of the flu watery nasal discharge clearing heat and relieving fidgetness Chinese medicine granules of embodiment 5 gained: in year June in June, 2013 to 2014,182 routine patients screen in Wu Suo hospital, wherein women's 90 examples, male's 92 examples, oldest 65 years old, minimal ages 5 years old, 35.4 years old mean age.Test within two weeks, this crowd is observed, record symptom and variation, be divided at random two groups, experimental group and matched group, experimental group is taken embodiment 5 products obtained therefroms, and matched group is taken other medicine (such as conventional medicines such as Radix Isatidis, HUOXIANG ZHENGQI SHUI, paracetamol, KUAIKE).Using method is: taken three times a day, and each bag, warm boiled water, 7 days courses for the treatment of.Curative effect situation criterion: cure: take a course for the treatment of of this product, fever phenomenon disappears, nasal obstruction watery nasal discharge etc., and uncomfortable disease is obviously improved, and the mental status obviously improves; Effective: take a course for the treatment of of this product, heating paresthesia goes down, malaise symptoms alleviates or part disappears, and energy strengthens; Invalid: take a course for the treatment of of this product, malaise symptoms is without significant change.
Table 1: take embodiment 5 product 5-65 year flu patients and take a course of therapy result
Therapeutic effect: experimental group is cured 80 examples (80%), effective 17 examples (17%), invalid 3 examples (3%), total effective rate 97%.Effect is better than matched group.
Take one the course for the treatment of symptom and change of spirit as shown in table 2.
Table 2:
The present invention selects selected Chinese crude drug epheday intermedia, Gypsum Fibrosum, Herba Peristrophes, Herba Menthae, Semen Cajani root, Flos Lonicerae, the Rhizoma Anemarrhenae, the Radix Angelicae Dahuricae, Folium Perillae, Fructus Arctii, graperoot, Herba Schizonepetae effect to work in coordination with, cold, fever watery nasal discharge is had to good effect, in side, Rhizoma Dioscoreae, Radix Ophiopogonis, Radix Glycyrrhizae Preparata, Fructus Jujubae master are at spleen reinforcing nourishing the stomach, the lung benefiting that promotes the production of body fluid, nourishing blood to tranquillize the mind, expelling phlegm for arresting cough, the warming middle-JIAO to arrest vomiting of adding Semen Armeniacae Amarum, Rhizoma Zingiberis Recens, Radix Platycodonis, Radix Peucedani, all medicines share evident in efficacy.Take a course for the treatment of, the symptoms such as heating, nasal obstruction, watery nasal discharge are basic all to disappear, and the mental status also takes a favorable turn.The total effective rate of experimental group can reach 97%, and invalid number of cases is only 3%, is compared to the total effective rate of matched group, and effect is more remarkable, is more suitable for promoting.
It should be pointed out that the specific embodiment is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clearly disclosed or according to undoubted the obtaining of the written description of file, all should think the claimed scope of this patent.
Claims (10)
1. flu watery nasal discharge clearing heat and relieving fidgetness Chinese medicine composition, is characterized in that, by following main materials medicine, is prepared from, and is weight portion: Herba Ephedrae 3-9, Gypsum Fibrosum 12-16, Herba Peristrophes 3-7, stir-baked SEMEN ARMENIACAE AMARUM 6-15, Rhizoma Dioscoreae 18-25, Herba Menthae 6-12, Radix Ophiopogonis 9-15, Semen Cajani root 4-9, Flos Lonicerae 6-12, Rhizoma Anemarrhenae 4-9, Radix Angelicae Dahuricae 5-15, Radix Glycyrrhizae Preparata 3-9, Rhizoma Zingiberis Recens 2-6, Fructus Jujubae 6-12, Folium Perillae 5-15, Radix Platycodonis 3-12, Radix Peucedani 9-16, Fructus Arctii 9-13, graperoot 4-6, Herba Schizonepetae 6-12.
2. Chinese medicine composition as claimed in claim 1, is characterized in that, by following main materials medicine, is prepared from, and is weight portion: Herba Ephedrae 5-7, Gypsum Fibrosum 13-15, Herba Peristrophes 4-6, stir-baked SEMEN ARMENIACAE AMARUM 9-12, Rhizoma Dioscoreae 20-23, Herba Menthae 8-10, Radix Ophiopogonis 11-13, Semen Cajani root 6-8, Flos Lonicerae 8-10, Rhizoma Anemarrhenae 5-7, Radix Angelicae Dahuricae 9-11, Radix Glycyrrhizae Preparata 5-7, Rhizoma Zingiberis Recens 3-5, Fructus Jujubae 8-10, Folium Perillae 9-11, Radix Platycodonis 6-8, Radix Peucedani 12-14, Fructus Arctii 10-12, graperoot 4-6, Herba Schizonepetae 8-10.
3. Chinese medicine composition as claimed in claim 1, is characterized in that, by following main materials medicine, is prepared from, and is weight portion: Herba Ephedrae 6, Gypsum Fibrosum 14, Herba Peristrophes 5, stir-baked SEMEN ARMENIACAE AMARUM 10.5, Rhizoma Dioscoreae 21.5, Herba Menthae 9, Radix Ophiopogonis 12, Semen Cajani root 7, Flos Lonicerae 9, the Rhizoma Anemarrhenae 6, the Radix Angelicae Dahuricae 10, Radix Glycyrrhizae Preparata 6, Rhizoma Zingiberis Recens 4, Fructus Jujubae 9, Folium Perillae 10, Radix Platycodonis 7, Radix Peucedani 13, Fructus Arctii 11, graperoot 5, Herba Schizonepetae 9.
4. the Chinese medicine composition as described in as arbitrary in claim 1-3, is characterized in that, this Chinese medicine composition is made to pharmaceutically acceptable decoction, pill and granule.
5. Chinese medicine composition as claimed in claim 4, is characterized in that, the preparation method of described decoction is:
(1) Gypsum Fibrosum is smashed, soaked 30 minutes, then intense fire is fried open, and turns 40 minutes at a simmer, filtering medicinal liquid, and recrement is watered and decocts, and mixes gained medicinal liquid twice;
(2) by Herba Ephedrae, stir-baked SEMEN ARMENIACAE AMARUM, Rhizoma Dioscoreae, Radix Ophiopogonis, Semen Cajani root, the Rhizoma Anemarrhenae, Rhizoma Zingiberis Recens, Fructus Jujubae, Radix Platycodonis, Radix Peucedani, Fructus Arctii, graperoot dedusting roguing, put into marmite intense fire and decoct to boiling, turn 30 minutes at a simmer, filtering medicinal liquid, recrement is watered and decocts, and mixes gained medicinal liquid twice;
(3), by Herba Peristrophes, Herba Menthae, Flos Lonicerae, the Radix Angelicae Dahuricae, Radix Glycyrrhizae Preparata, Folium Perillae, Herba Schizonepetae dedusting roguing, airtight decoction 20 minutes, repeats twice, mixes gained medicinal liquid;
(4) by decoct for above-mentioned three times medicinal liquid mix, sterile packaged, obtains the decoction of Chinese medicine composition.
6. Chinese medicine composition as claimed in claim 4, is characterized in that, the preparation method of described pill is:
(1) each crude drug is ground into fine powder, excessively after 80 mesh sieves, mixes;
(2) medicated powder is placed in the container of dried and clean, adds proper honey, even agglomerate is made in kneading in addition;
(3) rubbing pill after placement a period of time, after its dry tack free, with the standard pack of 4g/ ball, obtains the pill of Chinese medicine composition.
7. Chinese medicine composition as claimed in claim 4, is characterized in that, the preparation method of described granule is:
(1) by claim 5 gained Chinese medicine composition decoction, carry out centrifugalize, remove tiny medicinal residues;
(2) under 1.33kPa lower pressure environment, medicinal liquid is heated and concentrate, the time is 40 minutes;
(3) add again a certain proportion of sucrose and ethanol to mix with medicinal liquid, dry and be compressed into tablet;
(4) tablet is pulverized again, every 4g/ wraps, and obtains the granule of Chinese medicine composition.
8. the preparation method of Chinese medicinal composition granules as claimed in claim 7, is characterized in that, described step (2) heats medicinal liquid concentrated under 1.33kPa lower pressure environment, makes it become the thick paste that relative density is 1.30-1.35.
9. the preparation method of Chinese medicinal composition granules as claimed in claim 7, is characterized in that, described step (3) is mixed thick paste, sucrose, ethanol according to the ratio of 1.5:1:1-2.5:1:1 (being preferably 2:1:1).
10. the application of the Chinese medicine composition as described in as arbitrary in claim 1-3 when the medicine of preparation flu watery nasal discharge clearing heat and relieving fidgetness.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105213853A (en) * | 2015-10-29 | 2016-01-06 | 陆康 | A kind ofly treat high fever, the Chinese medicine composition of repeatedly having a fever and preparation method thereof |
| CN109528941A (en) * | 2018-12-14 | 2019-03-29 | 湖北荆江源制药股份有限公司 | A kind of Chinese medicine for treating cold in children |
| CN113662999A (en) * | 2020-05-13 | 2021-11-19 | 杨静 | Decoction for clearing lung and relieving cough and preparation method thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001314169A (en) * | 2000-05-09 | 2001-11-13 | Sakamoto Yakusoen:Kk | Kintoki ginger-based health food |
| CN101062104A (en) * | 2007-05-21 | 2007-10-31 | 王军 | Isatisroot granules for treating common cold |
| CN102657721A (en) * | 2012-04-16 | 2012-09-12 | 杭州天诚药业有限公司 | Cold granule and preparation method thereof |
| CN103054973A (en) * | 2012-12-23 | 2013-04-24 | 徐化利 | Traditional Chinese medicine prescription for treating cold |
-
2014
- 2014-08-26 CN CN201410423501.0A patent/CN104173977A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001314169A (en) * | 2000-05-09 | 2001-11-13 | Sakamoto Yakusoen:Kk | Kintoki ginger-based health food |
| CN101062104A (en) * | 2007-05-21 | 2007-10-31 | 王军 | Isatisroot granules for treating common cold |
| CN102657721A (en) * | 2012-04-16 | 2012-09-12 | 杭州天诚药业有限公司 | Cold granule and preparation method thereof |
| CN103054973A (en) * | 2012-12-23 | 2013-04-24 | 徐化利 | Traditional Chinese medicine prescription for treating cold |
Non-Patent Citations (2)
| Title |
|---|
| 吕奎礼: "麻杏石甘汤加减治疗流感57例临床分析", 《蛇志》 * |
| 唐晓红等: "小柴胡汤加减治验举隅", 《河南中医》 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105213853A (en) * | 2015-10-29 | 2016-01-06 | 陆康 | A kind ofly treat high fever, the Chinese medicine composition of repeatedly having a fever and preparation method thereof |
| CN109528941A (en) * | 2018-12-14 | 2019-03-29 | 湖北荆江源制药股份有限公司 | A kind of Chinese medicine for treating cold in children |
| CN113662999A (en) * | 2020-05-13 | 2021-11-19 | 杨静 | Decoction for clearing lung and relieving cough and preparation method thereof |
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