CN103585401A - Traditional Chinese medicine composition for treating bird flu and preparation method therefor. - Google Patents

Traditional Chinese medicine composition for treating bird flu and preparation method therefor. Download PDF

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Publication number
CN103585401A
CN103585401A CN201310171494.5A CN201310171494A CN103585401A CN 103585401 A CN103585401 A CN 103585401A CN 201310171494 A CN201310171494 A CN 201310171494A CN 103585401 A CN103585401 A CN 103585401A
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chinese medicine
medicine composition
radix
parts
traditional chinese
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CN201310171494.5A
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Chinese (zh)
Inventor
刘衍芬
贾富勃
姜凤丽
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Liaoning Agricultural Technical College
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Liaoning Agricultural Technical College
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Abstract

The invention discloses a traditional Chinese medicine composition for treating bird flu and a preparation method therefor. The traditional Chinese medicine composition comprises the following ingredients, by weight, 15-30 parts of honewort, 10-25 parts of scutellaria baicalensis, 20-30 parts of honeysuckle flowers, 10-20 parts of fructus forsythia, 20-25 parts of isatis roots, 15-30 parts of gypsum, 20-30 parts of kudzuvine roots, 10-20 parts of perilla leaves, 10-15 parts of balloonflower roots, 10-20 parts of Chinese yam, 5-15 parts of licorice, and 5-15 parts of gynostemma pentaphylla. The traditional Chinese medicine composition has functions of heat clearing, detoxifying, blood cooling, sore throat relieving, inflammation diminishing, pain relieving, cough relieving, phlegm eliminating, excitement tranquilizing and allaying, benefit supplementing, body strengthening, anti-virus, body immunity enhancing and the like. The traditional Chinese medicine composition has rapid treatment effects on rising of body temperature, lassitude, loss of appetite, dyspnea, decrease of egg production, shallow eggshell color, soft eggshells, increase of abnormal-shape eggs of fowls. The curative effects are exact, reliable and true. The traditional Chinese medicine composition is innocuous and unpoisonous to fowls, and is safe and reliable. During clinical usage, no any untoward effect of fowls is observed, and the composition is safe in clinical usage.

Description

A kind of Chinese medicine composition for the treatment of bird flu and preparation method thereof
Technical field
The invention belongs to Chinese veterinary medicinal composition, particularly be a kind of Chinese medicine composition preparation for the treatment of bird flu and preparation method thereof, belong to the treatment field of fowl diseases.
Background technology
Bird flu is the abbreviation of avian influenza, clinical symptoms shows as the fervescence of disease fowl, lassitude, appetite declines, cough, dyspnea, cockscomb, wattle edema, cyanosis, blepharoedema, the inflammation of eye conjunctiva, dysentery, ataxia, egg fowl egg production declines, eggshell color shoals, soft-shelled egg, abnormal-shape egg increase etc.If control measure are improper after morbidity, can cause tremendous economic loss to poultry cultivation industry, at present domestic and international application will be take amantadine and ribavirin preparation as main in the drug main for the treatment of bird flu, clinical efficacy is imprecise, and exist as residual, affect the toxic and side effects such as egg fowl laying rate recovery.Therefore developing the effective Chinese herbal treatment bird flu of wide spectrum becomes very necessary.
Summary of the invention
The present invention's technical problem first to be solved is the inapparent defect of curative effect that overcomes the chemicals existence of existing treatment bird flu, and the Chinese medicine composition of the treatment bird flu of a kind of instant effect, determined curative effect is provided.
Another technical problem to be solved by this invention is to provide a kind of method of preparing described treatment bird flu Chinese medicine composition.
Technical problem to be solved by this invention is achieved through the following technical solutions:
A bird flu Chinese medicine composition, comprises the component of following weight portion:
Radix Bupleuri 15-30 part, Radix Scutellariae 10-25 part, Flos Lonicerae 20-30 part, Fructus Forsythiae 10-20 part, Radix Isatidis 20-25 part, Gypsum Fibrosum 15-30 part, Radix Puerariae 20-30 part, Folium Perillae 10-20 part, Radix Platycodonis 10-15 part, Rhizoma Dioscoreae 10-20 part, Radix Glycyrrhizae 5-15 part, Herb Gynostemmae Pentaphylli 5-15 part.
Chinese medicine composition of the present invention be based on inventor to the research of bird flu pathogenesis and Therapeutic Principle thereof,
Simultaneously, according to inventor clinical experience and pharmaceutical research achievement for many years, filter out the crude drug of heat-clearing and toxic substances removing, cool the blood dissipate blood stasis, benefiting qi and nourishing blood, according to certain weight proportion prescription, form.
Radix Bupleuri: cold nature, bitter in the mouth.Enter liver, gallbladder meridian.Function cures mainly: antipyretic, antipyretic effect is steadily reliable, and calmness, analgesia, removes distending pain uncomfortable in chest, dissipating depression of QI regulating menstruation, anti-liver injury, the effect of strong inhibition influenza virus.
Radix Scutellariae: cold in nature, bitter in the mouth.Return lung, gallbladder, spleen, large intestine, small intestine meridian.Have heat clearing and damp drying, removing heat from blood is antiabortive, eliminating fire and detoxication effect.Cure mainly the diseases such as epidemic febrile disease, upper respiratory tract infection, cough due to lung-heat, jaundice due to damp-heat, pneumonia, dysentery, hemoptysis, conjunctival congestion, frequent fetal movement, hypertension, carbuncle furuncle.
Flos Lonicerae: cold in nature, sweet in the mouth.Return lung, stomach, the heart, large intestine channel.Have antibioticly, antipyretic, antiviral, strengthens immune function, and inflammation is had to obvious inhibitory action.
Fructus Forsythiae: cold nature, bitter in the mouth.Enter lung, the heart, gallbladder, small intestine meridian.Function cures mainly: dispelling wind and heat pathogens, heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.For carbuncle, scrofula, acute mastitis, erysipelas, anemopyretic cold, epidemic febrile disease is from the beginning of, warm joining the army, high hot excessive thirst, coma is sent out speckle, pyretic stranguria urine retention.
Radix Isatidis: cold in nature, bitter in the mouth.GUIXIN, stomach warp.There are heat-clearing and toxic substances removing, removing heat from blood sore-throat relieving, the effect of reducing swelling and alleviating pain.For maculae caused by violent heat pathogen, high heat headache, major part pestilence, influenza, encephalitis b, pneumonia, coma is told nosebleed, pharyngeal swelling, acute catarrhal conjunctivitis, upper respiratory tract infection.Meanwhile, can also promote the rehabilitation of health and the enhancing of immunity resistance.
Gypsum Fibrosum: cool in nature, sweet in the mouth, pungent.Attach to the lung and stomach meridians.There are the effects such as antipyretic, spasmolytic, antiinflammatory.
Radix Puerariae: cool in nature, sweet in the mouth, pungent.Enter spleen, stomach warp.Function cures mainly: expelling pathogenic factors from muscles for reducing heat, deliver rash, promoting the production of body fluid to quench thirst, yang invigorating antidiarrheal.For fever caused by exogenous pathogens, rigidity pain on the head and nape, epidemic febrile disease is thirsty, dysentery, diarrhea due to hypofunction of the spleen, clear YANG failing to ascend, hematodiarrhoea diarrhoea etc.
Folium Perillae: warm in nature, acrid in the mouth.Return lung, spleen channel.Function cures mainly: the cold expelling that induces sweat, and antibacterial removing toxic substances, relieving cough and reducing sputum, regulates the flow of vital energy antiabortive.For distension and fullness of the chest and abdomen, vomiting and nausea diarrhoea, blocks in pharynx, cold, and fever with aversion to cold, headache nasal obstruction, is doublely shown in cough or the person of not relaxing uncomfortable in chest.This product can be dispersed exterior cold, opens lung qi dispersing gas.
Radix Platycodonis: property is flat, bitter in the mouth, pungent.Enter lung meridian.There is remarkable antiinflammatory, relieving cough and expelling phlegm, antipyretic, calmness, analgesic effect.Function with cure mainly: lung qi dispersing cold expelling, clearing throat, expelling phlegm for arresting cough, evacuation of pus detumescence, sharp the five internal organs, fill blood, and mends five kinds of over strain, fosters the spirit of nobility.
Rhizoma Dioscoreae: property is flat, sweet in the mouth.Return lung, spleen, kidney channel.There is enhancing human body immunity function, tonify deficiency labor, physical strength profiting, aid digestion, cough-relieving, eliminates the phlegm, desensitization, the effect of anti-hepatic coma.Function with cure mainly: tonification is strong, spleen reinforcing nourishing the stomach, the lung benefiting that promotes the production of body fluid, the kidney invigorating arresting seminal emission.For insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney, and leukorrhagia, frequent micturition, deficiency-heat is quenched one's thirst, chronic nephritis, the diseases such as chronic enteritis.
Radix Glycyrrhizae: property is flat, sweet in the mouth.Enter lung, spleen, stomach warp.Have antibiotic, antiinflammatory, antipruritic, antitussive, eliminates the phlegm, calmness, antiviral, antiallergic, spasmolytic, enhancing non-specific immunity, to the poisoning effect that has detoxification ability of interior metabolism product.Function cures mainly: invigorating the spleen and replenishing QI, relieving spasm to stop pain, nourishing the lung to arrest cough, eliminating fire and detoxication.
Herb Gynostemmae Pentaphylli: cold in nature, sweet-bitter flavor.Enter lung, the heart, stomach warp.Function with cure mainly: tonification is strong, expelling phlegm for arresting cough, heat-clearing and toxic substances removing, tranquillizing and allaying excitement.
Full medicine share, complement each other, both increased the therapeutic effect of single medicine, therefore reduce again side effect, can play very soon the effects such as heat-clearing and toxic substances removing, cooling blood for hemostasis, clearing throat, evacuation of pus detumescence, anti-inflammatory analgetic, relieving cough and expelling phlegm, tranquillizing and allaying excitement, tonification are strong, antiviral, enhancing human body immunity power.For bird flu, there is significant curative effect.Clinical observation on the therapeutic effect confirmation, Chinese medicine composition of the present invention is fast for responding well to treatment of bird flu, and determined curative effect is reliable, true.Chinese medicine composition of the present invention is nontoxic for fowl, safe and reliable, does not observe fowl and occurs any untoward reaction, clinical use safety in use procedure.
Fowl described in the present invention is preferably laying hen, broiler, turkey.
The present invention's each taste crude drug used can be bought and obtain at pharmacy.
Various adjuvants required when medicine activity component of the present invention can add the dosage form of preparing oral formulations are prepared into any oral oral formulations of fowl that is suitable for clinically with conventional method of Chinese medicinal, for example, can be powder or oral liquid.
Thus, the invention provides a kind of method of preparing described Chinese medicine composition, comprising:
(1) by described weight portion, take each component;
(2) by each component mix homogeneously, pulverize, sieve (can be for example 60-400 mesh sieve, be preferably 80 orders), obtains.
The another kind of preparation method of Chinese medicine composition of the present invention:
(1) by described weight portion, take each component;
(2) component is pulverized and sieved to rear water and decoct, merge decoction liquor, filter, filtrate is condensed into clear paste, adds adjuvant or the excipient of preparations shaping, obtains.
Wherein in step (2), each component is pulverized and sieved and with 3-6 times of weight decocting, boil 2-3 time afterwards, decoct 1 hour at every turn.
The usage of Chinese medicine composition of the present invention and consumption: dosage of the present invention depends on the factors such as the occurring degree of concrete dosage form, bird flu and kind.As guidance: for powder, the powder boiled water of getting it filled gavages after soaking half an hour, the ill fowl body weight of the corresponding 1kg of 1g medicated powder; Every day 2 times, 3 days is a course for the treatment of, treats 2 courses for the treatment of.
The specific embodiment
Below in conjunction with specific embodiment, further describe the present invention, advantage and disadvantage of the present invention
Will be more clear along with description.But these embodiment are only exemplary, scope of the present invention are not formed to any restriction.It will be understood by those skilled in the art that lower without departing from the spirit and scope of the present invention and can the details of technical solution of the present invention and form be modified or be replaced, but these modifications and replacement all fall within the scope of protection of the present invention.
The preparation of embodiment 1 powder
(1) by described weight, take each component (unit: g): Radix Bupleuri 15, Radix Scutellariae 10, Flos Lonicerae 20, Fructus Forsythiae 10, Radix Isatidis 20, Gypsum Fibrosum 15, Radix Puerariae 20, Folium Perillae 10, Radix Platycodonis 10, Rhizoma Dioscoreae 10, Radix Glycyrrhizae 5, Herb Gynostemmae Pentaphylli 5;
(2) by each component mix homogeneously, pulverize, cross 120 mesh sieves, obtain.
The preparation of embodiment 2 powders
(1) by described weight, take each component (unit: g): Radix Bupleuri 30, Radix Scutellariae 25, Flos Lonicerae 30, Fructus Forsythiae 20, Radix Isatidis 25, Gypsum Fibrosum 30, Radix Puerariae 30, Folium Perillae 20, Radix Platycodonis 15, Rhizoma Dioscoreae 20, Radix Glycyrrhizae 15, Herb Gynostemmae Pentaphylli 15;
(2) by each component mix homogeneously, pulverize, cross 80 mesh sieves, obtain.
The preparation of embodiment 3 powders
(1) by described weight, take each component (unit: g): Radix Bupleuri 25, Radix Scutellariae 20, Flos Lonicerae 25, Fructus Forsythiae 15, Radix Isatidis 20, Gypsum Fibrosum 25, Radix Puerariae 25, Folium Perillae 15, Radix Platycodonis 10, Rhizoma Dioscoreae 15, Radix Glycyrrhizae 15, Herb Gynostemmae Pentaphylli 15;
(2) by each component mix homogeneously, pulverize, cross 200 mesh sieves, obtain.
The clinical observation on the therapeutic effect test of test example 1 traditional Chinese medicine composition for treating bird flu of the present invention
One, physical data: accepted 7 routine bird flus for medical treatment, egg fowl 4 examples wherein, 11500, poultry 3 examples, 16000.The sick fowl of accepting for medical treatment all in various degree show fervescence, lassitude, appetite decline, dyspnea, cockscomb, wattle edema, dysentery, row's yellow green loose stool, egg fowl egg production declines, eggshell color shoals, soft-shelled egg, abnormal-shape egg increase etc., meet clinical bird flu diagnostic criteria
Two, trial drug
The medicine that embodiment of the present invention 1-3 is prepared.
Three, Therapeutic Method
Powder: for powder, the powder boiled water of getting it filled gavages after soaking, the ill fowl body weight of the corresponding 1kg of 1g medicated powder; Every day 2 times, 3 days is a course for the treatment of, treats 2 courses for the treatment of.
Four, efficacy assessment standard
Efficacy assessment standard and foundation:
Recovery from illness: treat after 1 course for the treatment of, fowl fervescence, lassitude, appetite decline, dyspnea, cockscomb, wattle edema, dysentery, egg fowl egg production declines, eggshell color shoals, soft-shelled egg, abnormal-shape egg increase symptom and disappear completely, and it is normal that function is recovered completely.
Remarkable: to treat after 1 course for the treatment of, fowl fervescence, lassitude, appetite decline, dyspnea, cockscomb, wattle edema, dysentery, egg fowl egg production declines, eggshell color shoals, soft-shelled egg, abnormal-shape egg increase symptom and substantially disappear, and it is normal that function is recovered substantially.
Effective: treat after 2 courses for the treatment of, fowl fervescence, lassitude, appetite decline, dyspnea, cockscomb, wattle edema, dysentery, egg fowl egg production declines, eggshell color shoals, soft-shelled egg, abnormal-shape egg increase symptom and alleviate to some extent, and function is recovered to some extent.
Invalid: treat after 2 courses for the treatment of, fowl fervescence, lassitude, appetite decline, dyspnea, cockscomb, wattle edema, dysentery, egg fowl egg production declines, eggshell color shoals, soft-shelled egg, abnormal-shape egg increases symptom and function is not improved.
Five, clinical observation result
Clinical observation result in Table 1, table 2.
The clinical observation on the therapeutic effect result of the test of table 1 traditional Chinese medicine composition for treating laying hen of the present invention bird flu
The clinical observation on the therapeutic effect result of the test of table 2 traditional Chinese medicine composition for treating broiler of the present invention bird flu
With the 2nd day of traditional Chinese medicine composition for treating fowl of the present invention, great majority are treated fervescence, lassitude, appetite decline, dyspnea, cockscomb, the wattle edema of fowl, dysentery, egg fowl egg production declines, eggshell color shoals, soft-shelled egg, abnormal-shape egg increases symptom all has obviously and alleviate; Treat the 3rd day, treated fervescence, lassitude, appetite decline, dyspnea, cockscomb, the wattle edema of fowl, dysentery, egg fowl egg production declines, eggshell color shoals, soft-shelled egg, abnormal-shape egg increase symptom and significantly improve; By the 5th day that treats, the fervescence of fowl, lassitude, appetite decline, dyspnea, cockscomb, wattle edema, dysentery, the symptom that egg fowl egg production declines, eggshell color shoals, soft-shelled egg, abnormal-shape egg increase disappears substantially, and the every function of health recovers normal substantially.Clinical observation on the therapeutic effect result shows, Chinese medicine composition of the present invention is fast, evident in efficacy for responding well to treatment of bird flu; In whole therapeutic process, do not observe the fowl being treated and only occur any untoward reaction, show Chinese medicine composition clinical practice of the present invention safely, have no side effect.

Claims (10)

1. treat a Chinese medicine composition for bird flu, it is characterized in that said composition prepared by following raw material and consumption: Radix Bupleuri 15-30 part, Radix Scutellariae 10-25 part, Flos Lonicerae 20-30 part, Fructus Forsythiae 10-20 part, Radix Isatidis 20-25 part, Gypsum Fibrosum 15-30 part, Radix Puerariae 20-30 part, Folium Perillae 10-20 part, Radix Platycodonis 10-15 part, Rhizoma Dioscoreae 10-20 part, Radix Glycyrrhizae 5-15 part, Herb Gynostemmae Pentaphylli 5-15 part.
2. according to Chinese medicine composition claimed in claim 1, it is characterized in that, the weight portion of each component is: Radix Bupleuri 20-30 part, Radix Scutellariae 15-25 part, Flos Lonicerae 25-30 part, Fructus Forsythiae 10-15 part, Radix Isatidis 20-25 part, Gypsum Fibrosum 15-20 part, Radix Puerariae 20-30 part, Folium Perillae 10-20 part, Radix Platycodonis 10-15 part, Rhizoma Dioscoreae 10-20 part, Radix Glycyrrhizae 5-15 part, Herb Gynostemmae Pentaphylli 10-15 part.
3. according to Chinese medicine composition claimed in claim 1, it is characterized in that, the weight portion of each component is: Radix Bupleuri 15, Radix Scutellariae 20, Flos Lonicerae 25, Fructus Forsythiae 15, Radix Isatidis 20, Gypsum Fibrosum 15, Radix Puerariae 20, Folium Perillae 10, Radix Platycodonis 10, Rhizoma Dioscoreae 10, Radix Glycyrrhizae 10, Herb Gynostemmae Pentaphylli 10.
4. the Chinese medicine composition described in any one according to claim 1-3, is characterized in that: be prepared into any fowl acceptable suitable formulations clinically.
5. according to Chinese medicine composition claimed in claim 4, it is characterized in that: described preparation is oral formulations.
6. according to Chinese medicine composition claimed in claim 5, it is characterized in that: described oral formulations comprises powder, granule or oral liquid.
7. a method of preparing claim 1-3 Chinese medicine composition described in any one, comprises the following steps:
(1) by described weight portion, take each component;
(2) each component is pulverized, sieved, obtain.
8. a method of preparing claim 1-3 Chinese medicine composition described in any one, comprises the following steps:
(1) by described weight portion, take each component;
(2) component is pulverized and sieved to rear water and decoct, decoction liquor is filtered, and filtrate is condensed into clear paste, adds adjuvant or the excipient of preparations shaping, obtains.
9. claim 1-3 Chinese medicine composition purposes in preparation treatment bird flu medicine described in any one.
10. according to purposes claimed in claim 9, it is characterized in that: described fowl is laying hen, broiler, turkey.
CN201310171494.5A 2013-03-26 2013-03-26 Traditional Chinese medicine composition for treating bird flu and preparation method therefor. Pending CN103585401A (en)

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CN106075029A (en) * 2016-07-29 2016-11-09 山东省农业科学院家禽研究所 A kind of prevent and treat chicken and defend the Chinese medicine oral liquid of syndrome in QI system

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CN103976149A (en) * 2014-04-28 2014-08-13 彭鸿贰 Chinese medicine feed additive for avian influenza prevention
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CN105582058A (en) * 2014-11-13 2016-05-18 天津市中敖饲料有限公司 Traditional Chinese medicinal oral liquid for treating swine common cold and preparation method of traditional Chinese medicinal oral liquid
TWI552757B (en) * 2014-12-12 2016-10-11 大仁科技大學 Anti-h1n1 virus compound herbs extract, oral formulas and preparation method thereof
CN106075029A (en) * 2016-07-29 2016-11-09 山东省农业科学院家禽研究所 A kind of prevent and treat chicken and defend the Chinese medicine oral liquid of syndrome in QI system
CN106075029B (en) * 2016-07-29 2019-07-02 山东省农业科学院家禽研究所 A kind of prevention and treatment chicken defends the traditional Chinese medicine oral liquid of Qi phase syndrome

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