CN112057517A - Traditional Chinese medicine composition for improving survival rate of weaned piglets, preparation method and feeding method - Google Patents

Traditional Chinese medicine composition for improving survival rate of weaned piglets, preparation method and feeding method Download PDF

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CN112057517A
CN112057517A CN202011149025.XA CN202011149025A CN112057517A CN 112057517 A CN112057517 A CN 112057517A CN 202011149025 A CN202011149025 A CN 202011149025A CN 112057517 A CN112057517 A CN 112057517A
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parts
chinese medicine
traditional chinese
water
survival rate
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李孝文
刘思当
郑乾坤
刘东敏
李敏
王敏
殷圣洁
肖伟
郑龙祥
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DELISI GROUP Ltd
Shandong Agricultural University
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DELISI GROUP Ltd
Shandong Agricultural University
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233Bupleurum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/17Gnetophyta, e.g. Ephedraceae (Mormon-tea family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/29Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
    • A61K36/296Epimedium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718Coptis (goldthread)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • A61K36/744Gardenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/78Saururaceae (Lizard's-tail family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

Abstract

The invention discloses a traditional Chinese medicine composition for improving the survival rate of weaned piglets, a preparation method and a feeding method, wherein the traditional Chinese medicine composition comprises the following traditional Chinese medicine components in parts by weight: 80-120 parts of radix bupleuri, 60-80 parts of ephedra, 50-70 parts of almond, 140-160 parts of epimedium herb, 140-160 parts of astragalus, 80-120 parts of scutellaria baicalensis, 60-80 parts of coptis chinensis, 40-60 parts of honeysuckle, 80-120 parts of houttuynia cordata, 40-60 parts of gardenia and 80-120 parts of liquorice. Extracting the traditional Chinese medicine composition with water and concentrating to obtain decoction dregs and a traditional Chinese medicine concentrated solution, and adding the decoction dregs into pig feed according to 1000 g/ton to feed piglets; adding the traditional Chinese medicine concentrated solution into weaned piglet drinking water according to the dosage of 10 mL/head/day. The feed is used for feeding weaned piglets, and can effectively improve the immunity of swinery and improve the survival rate of the piglets.

Description

Traditional Chinese medicine composition for improving survival rate of weaned piglets, preparation method and feeding method
Technical Field
The invention relates to the technical field of veterinary medicines, in particular to a veterinary traditional Chinese medicine for improving the survival rate of weaned piglets.
Background
Currently, with the rapid development of the scale process of pig raising in China since the African Swine Fever (ASF) is first reported and widely spread in China in 8 months in 2018, the format of scale pig raising is already irreversible and becomes the mainstream mode of pig raising in the present period and in the future. Also, with the upgrading of ASF prevention and control, biosafety methods have become the primary means of disease prevention and control for many swine production practitioners. The mainstream scale of pig farm viral disease began to shift to a clean route and has also achieved better results in practice. However, current disease problems in pig farms remain a major factor that plagues the health of the herd, particularly the survival rate and healthy production of the herd after weaning. The death and elimination of about 10 percent from national weaning to marketing, excluding the influence of the main viral diseases, and the influence of other related influencing factors accounting for about 30 to 60 percent, namely 3 to 6 percent of the whole body. During the past 10 years, this proportion has relied primarily on antibiotic reduction for staged mortality, but with national appeal to antibiotic use restrictions and health production management, reducing or restricting antibiotic use has become a current industry pain point.
The factors influencing the effective survival rate of the pig group after weaning still are bacterial secondary infection, porcine circovirus disease (PCV) and secondary bacterial and mycoplasma infection thereof caused by porcine reproductive and respiratory syndrome (commonly called porcine reproductive and respiratory syndrome, PRRS), mainly manifested by fever, nervous symptoms, sudden death, respiratory infectious diseases, chronic elimination and the like of the pig group after weaning, and the main reasons are that the pig immunity is reduced due to immunosuppression and nonspecific immune deficiency of the pig group, and then a plurality of conditional pathogenic bacteria (such as streptococcus suis, haemophilus parasuis, infectious actinobacillus pleuropneumoniae and the like) are bred and cause population infection and death and culling increase or poor prognosis. When a pig farm is infected and blue-ear disease occurs, the disease is most obvious in the stage of nursing piglets, and the survival rate and the slaughtering quality of swineries are seriously influenced. The symptoms are that the body temperature rises to 40-41 ℃, the breathing is difficult, the piglets breathe in an abdominal way, the appetite is reduced, the emaciation is thin, the skin is whitish, the hair is rough, the eyelid is edematous, the ear and the body surface of a few piglets are purplish, the death rate of the piglets before weaning is 80-100 percent, the death rate of the piglets after weaning is 20-50 percent, and the death rate is higher if multiple infections occur. PRRS infection happens to a certain pig farm in Shandong in 10 months in 2019, and the PRRS infection is confirmed to be infected by an NADC30-like strain, the pregnant sow abortion rate of a sow group is 7.2%, the PRRSV positive rate of the serum of a weaned piglet is 30%, and the death and culling rate of the weaned piglet is 18-23% when the weaned piglet is 70 days old.
The traditional Chinese medicine feeding is used as an important means and material for preventing and treating diseases in the traditional Chinese medicine, and has long-term use and good effect in the history of human beings. The Chinese medicinal composition has the characteristics of improving nonspecific immunity, resisting viruses, resisting bacteria, regulating population and the like, has no restriction problems of related antibiotic residues in medicinal plants of most of Chinese medicaments, makes up the defects of a plurality of antibiotics, and is a model for preventing diseases.
Disclosure of Invention
The first technical problem to be solved by the invention is as follows: aiming at the defects in the prior art, the traditional Chinese medicine composition for improving the survival rate of weaned piglets is provided, is used for feeding piglets, can obviously improve the survival rate of swinery, is low in price and convenient to use, and effectively improves the health condition of the swinery affected by PRRS and other diseases.
The second technical problem to be solved by the invention is: aiming at the defects in the prior art, the preparation method of the traditional Chinese medicine composition for improving the survival rate of weaned piglets is provided, the prepared traditional Chinese medicine is used for feeding piglets, the survival rate of the swinery can be obviously improved, the price is low, the use is convenient, and the health condition of the swinery affected by PRRS and other diseases is effectively improved.
The third technical problem to be solved by the invention is: aiming at the defects in the prior art, the method for feeding pigs with the traditional Chinese medicine composition for improving the survival rate of weaned piglets is provided, the survival rate of the swinery can be obviously improved, the price is low, the use is convenient, and the health condition of the swinery affected by PRRS and other diseases is effectively improved.
In order to solve the first technical problem, the technical scheme of the invention is as follows:
a traditional Chinese medicine composition for improving the survival rate of weaned piglets comprises the following traditional Chinese medicine components in parts by weight: 80-120 parts of radix bupleuri, 60-80 parts of ephedra, 50-70 parts of almond, 140-160 parts of epimedium herb, 140-160 parts of astragalus, 80-120 parts of scutellaria baicalensis, 60-80 parts of coptis chinensis, 40-60 parts of honeysuckle, 80-120 parts of houttuynia cordata, 40-60 parts of gardenia and 80-120 parts of liquorice.
As a preferred technical scheme, the traditional Chinese medicine composition for improving the survival rate of weaned piglets comprises the following traditional Chinese medicine components in parts by weight: 100 parts of radix bupleuri, 70 parts of ephedra, 60 parts of almond, 150 parts of epimedium, 150 parts of astragalus, 100 parts of scutellaria, 70 parts of coptis, 50 parts of honeysuckle, 100 parts of cordate houttuynia, 50 parts of gardenia and 100 parts of liquorice.
The traditional Chinese medicine composition of the invention comprises the following components in formula:
bupleurum root, radix bupleuri. It can be used for treating stagnation of qi due to depression of the liver, distending pain of chest and hypochondrium, rectocele, metrorrhagia, and menoxenia.
Ma Huang is pungent, slightly bitter and warm. It enters lung and bladder meridians. Induce sweating to relieve exterior syndrome, ventilate lung and relieve asthma, induce diuresis to alleviate edema.
Apricot kernel, bitter in property and warm in nature, is toxic, has the effects of eliminating phlegm, relieving cough, relieving asthma and lubricating intestines, and can be used for treating exogenous cough, fullness and asthma, throat impediment, intestinal dryness, constipation and other symptoms.
Epimedium herb, herba Epimedii is warm in nature, pungent and sweet in flavor. It enters liver and kidney meridians. Tonify kidney yang, strengthen tendons and bones, dispel wind-damp. Yang tonifying medicine belonging to deficiency tonifying medicine and classification
Huang Qi is slightly warm in nature and sweet in taste. It enters spleen and lung meridians. Invigorating qi, consolidating superficial resistance, promoting urination, expelling toxin, expelling pus, and promoting granulation. They belong to the category of qi tonics under deficiency-tonifying herbs.
Baikal skullcap root, radix Scutellariae is cold in nature and bitter in taste. It enters lung meridian, gallbladder meridian, spleen meridian, large intestine meridian, and small intestine meridian. Clearing heat, eliminating dampness, purging pathogenic fire, removing toxic substances, stopping bleeding, and preventing miscarriage. Heat-clearing and dampness-drying herbs belonging to the category of heat-clearing herbs
Huang Lian is cold in nature and bitter in taste. They enter heart, spleen, stomach, liver, gallbladder and large intestine meridians. Clear heat and dry dampness, purge fire and remove toxicity. Herbs for clearing heat and drying dampness belong to the category of heat-clearing herbs.
Honeysuckle flower, flos Lonicerae, cold in nature, sweet in taste. It enters lung meridian, heart meridian and stomach meridian. Clearing away heat and toxic material, and cooling and dispelling wind-heat. Belonging to the category of heat-clearing herbs.
Yu xing Cao is slightly cold in nature and pungent in flavor. It enters lung meridian. Clearing away heat and toxic material, eliminating carbuncle, expelling pus, promoting urination, and treating stranguria. Belonging to the category of heat-clearing herbs.
Zhi Zi is cold in nature and bitter in taste. They enter heart meridian, lung meridian and triple energizer meridian. Purging pathogenic fire, relieving restlessness, clearing away heat, promoting urination, cooling blood, and removing toxic substances; it can be used topically for relieving swelling and pain. Belongs to heat-clearing and fire-purging herbs under the category of heat-clearing herbs.
Licorice root, radix Glycyrrhizae is neutral in nature and sweet in taste. They enter heart, stomach, spleen and lung meridians. Invigorating spleen and replenishing qi, relieving cough and eliminating phlegm, relieving spasm and relieving pain, and harmonizing drug property. They belong to qi tonics classified under deficiency tonics.
In order to solve the second technical problem, the technical solution of the present invention is:
the preparation method of the traditional Chinese medicine composition for improving the survival rate of weaned piglets comprises the following steps:
(1) preparing raw materials: selecting the raw materials of the traditional Chinese medicine components, screening to remove impurities, and weighing the raw material components according to the parts by weight;
(2) crushing: respectively crushing the traditional Chinese medicine components by using a coarse crusher, and controlling the discharged particles to be 0.5-20 mm;
(3) water leaching: mixing and weighing the crushed traditional Chinese medicine components, mixing the traditional Chinese medicine components with deionized water according to the weight ratio of 1:10, and soaking for 30-40 min;
(4) water extraction: heating the raw material mixture soaked in the water in the step (3) in a non-iron container to boiling while stirring, continuously carrying out slow fire for 50-80 min after boiling, then filtering, and filtering out water decoction; adding deionized water into the filter residue according to the weight ratio of 1:10, repeating the water decoction operation, and filtering out water decoction; the medicine residues are reserved;
(5) concentration: mixing the two water decoctions, heating to boil, and continuously boiling and concentrating to obtain Chinese medicinal concentrated solution;
(6) subpackaging and storing: and subpackaging the Chinese medicinal concentrated solution, sterilizing and storing.
Preferably, the concentration is carried out by boiling continuously until the concentration is equal to the weight parts of the raw material components. Namely, 1000g of the traditional Chinese medicine raw materials are extracted by water and concentrated to 1000mL of water decoction.
In order to solve the third technical problem, the technical scheme of the invention is as follows:
the method for feeding pigs with the traditional Chinese medicine composition for improving the survival rate of weaned piglets comprises the steps of carrying out water extraction and concentration on the traditional Chinese medicine composition to obtain decoction dregs and a traditional Chinese medicine concentrated solution, adding the decoction dregs into pig feed according to 1000 g/ton, uniformly stirring, and feeding the piglets according to a normal feeding amount; the traditional Chinese medicine concentrated solution is added into the drinking water of the weaned piglets according to the dosage of 10 mL/head/day.
Due to the adoption of the technical scheme, the invention has the beneficial effects that:
the traditional Chinese medicine composition for improving the survival rate of weaned piglets comprises the following traditional Chinese medicine components in parts by weight: 80-120 parts of radix bupleuri, 60-80 parts of ephedra, 50-70 parts of almond, 140-160 parts of epimedium herb, 140-160 parts of astragalus, 80-120 parts of scutellaria baicalensis, 60-80 parts of coptis chinensis, 40-60 parts of honeysuckle, 80-120 parts of houttuynia cordata, 40-60 parts of gardenia and 80-120 parts of liquorice. The feed adopts the medicinal plants with low price and effective formula, the medicinal plants (radix bupleuri) with mild cooling effect, the Chinese medicinal components (epimedium, coptis chinensis, astragalus mongholicus, scutellaria baicalensis and honeysuckle) for improving the non-specific immunity and virus resistance of a group, the Chinese medicinal components (ephedra and almond) for relieving the respiratory symptoms, and the liquorice for neutralizing various medicinal effects, so that the Chinese medicinal components have monarch, minister, assistant and guide interaction, are used for feeding weaned piglets, can effectively improve the immunity of the piglets and improve the survival rate of the piglets.
The piglet is fed by using a traditional Chinese medicine feeding method, the effective action and the full utilization of the extract and the unextracted extract are improved by adopting the medicinal plants with low price and effective formula through the preparation method of crushing and water decoction, the piglet feed is used for preventing diseases and improving the immunity of weaned pigs, and meanwhile, the piglet feed can realize industrial production in use, is simple and convenient to operate and has obvious clinical effect.
Drawings
The invention is further illustrated with reference to the following figures and examples.
FIG. 1 is a bar graph of survival rates of weaned piglets fed for six weeks in the experimental example of the present invention;
in the figure, the group A adopts the traditional Chinese medicine composition and the feeding method of the invention;
group B adopts a common antibiotic feeding method;
group C is a blank control group.
Detailed Description
The invention is further illustrated below with reference to the figures and examples. It should be understood that these examples are for illustrative purposes only and are not intended to limit the scope of the present invention. Further, it should be understood that various changes or modifications of the present invention may be made by those skilled in the art after reading the teaching of the present invention, and such equivalents may fall within the scope of the present invention as defined in the appended claims.
Example 1
A traditional Chinese medicine composition for improving the survival rate of weaned piglets comprises the following traditional Chinese medicine components in parts by weight: 90 parts of radix bupleuri, 65 parts of ephedra, 55 parts of almond, 145 parts of epimedium, 145 parts of astragalus, 90 parts of scutellaria, 65 parts of coptis, 45 parts of honeysuckle, 90 parts of cordate houttuynia, 45 parts of gardenia and 90 parts of liquorice.
Example 2
A traditional Chinese medicine composition for improving the survival rate of weaned piglets comprises the following traditional Chinese medicine components in parts by weight: 95 parts of bupleurum, 72 parts of ephedra, 62 parts of almond, 150 parts of epimedium, 150 parts of astragalus, 108 parts of scutellaria, 68 parts of coptis, 48 parts of honeysuckle, 95 parts of heartleaf houttuynia herb, 48 parts of gardenia and 95 parts of liquorice.
Example 3
A traditional Chinese medicine composition for improving the survival rate of weaned piglets comprises the following traditional Chinese medicine components in parts by weight: 110 parts of bupleurum, 75 parts of ephedra, 65 parts of almond, 155 parts of epimedium, 155 parts of astragalus, 110 parts of scutellaria, 75 parts of coptis, 55 parts of honeysuckle, 110 parts of cordate houttuynia, 55 parts of gardenia and 110 parts of liquorice.
Example 4
A traditional Chinese medicine composition for improving the survival rate of weaned piglets comprises the following traditional Chinese medicine components in parts by weight: 100 parts of radix bupleuri, 70 parts of ephedra, 60 parts of almond, 150 parts of epimedium, 150 parts of astragalus, 100 parts of scutellaria, 70 parts of coptis, 50 parts of honeysuckle, 100 parts of cordate houttuynia, 50 parts of gardenia and 100 parts of liquorice.
Example 5
(1) Preparing raw materials: picking the raw materials of the traditional Chinese medicine components described in the embodiment 1, screening and removing impurities, and weighing the raw materials according to the weight parts to be 1000 Kg;
(2) crushing: respectively crushing the traditional Chinese medicine components by using a coarse crusher, and controlling the discharged particles to be 0.5-2 mm;
(3) water leaching: mixing the pulverized traditional Chinese medicine components, weighing, mixing with deionized water according to a weight ratio of 1:10, and soaking for 30 min;
(4) water extraction: heating the raw material mixture soaked in the water in the step (3) in a non-iron container to boil, stirring while heating, continuously carrying out slow fire for 60min after boiling, then filtering, and filtering out water decoction; adding deionized water into the filter residue according to the weight ratio of 1:10, repeating the water decoction operation, and filtering out water decoction; the medicine residues are reserved;
(5) concentration: mixing the two water decoctions, heating to boil, and continuously boiling and concentrating to obtain Chinese medicinal concentrated solution; the Chinese medicinal raw materials are extracted by water and concentrated to 1000L of water decoction.
(6) Subpackaging and storing: and subpackaging the Chinese medicinal concentrated solution, sterilizing and storing.
Example 6
(1) Preparing raw materials: picking the raw materials of the traditional Chinese medicine components described in the embodiment 2, screening and removing impurities, and weighing the raw materials according to the parts by weight to be 1000 Kg;
(2) crushing: respectively crushing the traditional Chinese medicine components by using a coarse crusher, and controlling the discharged particles to be 1-5 mm;
(3) water leaching: mixing the pulverized traditional Chinese medicine components, weighing, mixing with deionized water according to a weight ratio of 1:10, and soaking for 35 min;
(4) water extraction: heating the raw material mixture soaked in the water in the step (3) in a non-iron container to boil, stirring while heating, continuously carrying out slow fire for 65min after boiling, then filtering, and filtering out water decoction; adding deionized water into the filter residue according to the weight ratio of 1:10, repeating the water decoction operation, and filtering out water decoction; the medicine residues are reserved;
(5) concentration: mixing the two water decoctions, heating to boil, and continuously boiling and concentrating to obtain Chinese medicinal concentrated solution; the Chinese medicinal raw materials are extracted by water and concentrated to 1000L of water decoction.
(6) Subpackaging and storing: and subpackaging the Chinese medicinal concentrated solution, sterilizing and storing.
Example 7
(1) Preparing raw materials: picking the raw materials of the traditional Chinese medicine components described in the embodiment 4, screening and removing impurities, and weighing the raw materials according to the parts by weight to be 1000 Kg;
(2) crushing: respectively crushing the traditional Chinese medicine components by using a coarse crusher, and controlling the discharged particles to be 0.8-5 mm;
(3) water leaching: mixing the pulverized Chinese medicinal components, weighing, mixing with deionized water at a weight ratio of 1:10, and soaking for 36 min;
(4) water extraction: heating the raw material mixture soaked in the water in the step (3) in a non-iron container to boil, stirring while heating, continuously carrying out slow fire for 70min after boiling, then filtering, and filtering out water decoction; adding deionized water into the filter residue according to the weight ratio of 1:10, repeating the water decoction operation, and filtering out water decoction; the medicine residues are reserved;
(5) concentration: mixing the two water decoctions, heating to boil, and continuously boiling and concentrating to obtain Chinese medicinal concentrated solution; the Chinese medicinal raw materials are extracted by water and concentrated to 1000L of water decoction.
(6) Subpackaging and storing: and subpackaging the Chinese medicinal concentrated solution, sterilizing and storing.
Test examples
Experimental piglets come from a pig farm of certain scale in Shandong, weaned piglets are randomly selected and are averagely divided into three groups: group A, group B and group C. Each group was randomly divided into four parallel control groups A1-A4, B1-B4, C1-C4.
Feeding the group A with the traditional Chinese medicine composition, extracting the traditional Chinese medicine composition in the embodiment 4 with water, concentrating to obtain decoction dregs and a traditional Chinese medicine concentrated solution, adding the decoction dregs into pig feed according to 1000 g/ton, uniformly stirring, and feeding piglets according to a normal feeding amount; the traditional Chinese medicine concentrated solution is added into the drinking water of the weaned piglets according to the dosage of 10 mL/head/day.
The group B adopts a common antibiotic feeding method: the antibiotic uses 20 percent of acetylisovaleryl tylosin and 10 percent of compound amoxicillin soluble powder, and adopts a feed adding method, and the antibiotic is continuously used in the whole experimental stage according to the dosage of 2kg/T of acetylisovaleryl tylosin and 1kg/T of compound amoxicillin.
Group C was a blank control group and was fed the same diet normally.
After the three groups were fed for 6 weeks, the results are shown in the following table 1:
TABLE 1
Figure BDA0002740588790000081
The above tests show that: using the feeding method of the invention, the piglet group showed good effect within 6 weeks after weaning, which is significantly superior to the general antibiotic 'health care method' (group B) and the blank control group without any treatment (group C). The survival rate of piglets can be effectively improved under the threat of PRRS epidemic situation.

Claims (5)

1. A traditional Chinese medicine composition for improving the survival rate of weaned piglets is characterized by comprising the following traditional Chinese medicine components in parts by weight: 80-120 parts of radix bupleuri, 60-80 parts of ephedra, 50-70 parts of almond, 140-160 parts of epimedium herb, 140-160 parts of astragalus, 80-120 parts of scutellaria baicalensis, 60-80 parts of coptis chinensis, 40-60 parts of honeysuckle, 80-120 parts of houttuynia cordata, 40-60 parts of gardenia and 80-120 parts of liquorice.
2. The traditional Chinese medicine composition for improving the survival rate of weaned piglets according to claim 1, which is characterized by comprising the following traditional Chinese medicine components in parts by weight: 100 parts of radix bupleuri, 70 parts of ephedra, 60 parts of almond, 150 parts of epimedium, 150 parts of astragalus, 100 parts of scutellaria, 70 parts of coptis, 50 parts of honeysuckle, 100 parts of cordate houttuynia, 50 parts of gardenia and 100 parts of liquorice.
3. The method of preparing a Chinese medicinal composition for improving survival rate of weaned piglets according to claim 1, comprising the steps of:
(1) preparing raw materials: selecting the raw materials of the traditional Chinese medicine components, screening to remove impurities, and weighing the raw material components according to the parts by weight;
(2) crushing: respectively crushing the traditional Chinese medicine components by using a coarse crusher, and controlling the discharged particles to be 0.5-20 mm;
(3) water leaching: mixing and weighing the crushed traditional Chinese medicine components, mixing the traditional Chinese medicine components with deionized water according to the weight ratio of 1:10, and soaking for 30-40 min;
(4) water extraction: heating the raw material mixture soaked in the water in the step (3) in a non-iron container to boiling while stirring, continuously carrying out slow fire for 50-80 min after boiling, then filtering, and filtering out water decoction; adding deionized water into the filter residue according to the weight ratio of 1:10, repeating the water decoction operation, and filtering out water decoction; the medicine residues are reserved;
(5) concentration: mixing the two water decoctions, heating to boil, and continuously boiling and concentrating to obtain Chinese medicinal concentrated solution;
(6) subpackaging and storing: and subpackaging the Chinese medicinal concentrated solution, sterilizing and storing.
4. The method of preparing a Chinese medicinal composition for improving survival rate of weaned piglets according to claim 3, wherein: during the concentration, the mixture is continuously boiled and concentrated to be the traditional Chinese medicine concentrated solution which is equivalent to the weight parts of the raw material components.
5. The feeding method of the pigs by using the traditional Chinese medicine composition for improving the survival rate of weaned piglets is characterized by comprising the following steps: extracting the traditional Chinese medicine composition of claim 1 with water and concentrating to obtain decoction dregs and a traditional Chinese medicine concentrated solution, adding the decoction dregs into pig feed according to 1000 g/ton, uniformly stirring, and feeding piglets according to a normal feeding amount; the traditional Chinese medicine concentrated solution is added into the drinking water of the weaned piglets according to the dosage of 10 mL/head/day.
CN202011149025.XA 2020-10-23 2020-10-23 Traditional Chinese medicine composition for improving survival rate of weaned piglets, preparation method and feeding method Pending CN112057517A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112841433A (en) * 2020-12-31 2021-05-28 江西正邦动物保健品有限公司 Feeding composition for improving immunity of swinery and purifying vivotoxin and preparation method thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102846866A (en) * 2012-08-28 2013-01-02 郑州后羿制药有限公司 Chinese medicine composition for prevention and control of porcine circovirus disease and preparation method thereof
CN105982995A (en) * 2016-01-28 2016-10-05 宿州瑞泰农业发展有限公司 Specific traditional Chinese veterinary oral medicine for treating chronic hog cholera
CN107349385A (en) * 2017-07-19 2017-11-17 济南金牧生物科技有限公司 One group is used for fermented tcm composition that live pig nonreactive cultivates and preparation method thereof
CN109420046A (en) * 2017-08-25 2019-03-05 湖南民康生物技术研究所 A kind of method of herbal prescription preparation prevention and treatment porcine hyperthermia drug

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102846866A (en) * 2012-08-28 2013-01-02 郑州后羿制药有限公司 Chinese medicine composition for prevention and control of porcine circovirus disease and preparation method thereof
CN105982995A (en) * 2016-01-28 2016-10-05 宿州瑞泰农业发展有限公司 Specific traditional Chinese veterinary oral medicine for treating chronic hog cholera
CN107349385A (en) * 2017-07-19 2017-11-17 济南金牧生物科技有限公司 One group is used for fermented tcm composition that live pig nonreactive cultivates and preparation method thereof
CN109420046A (en) * 2017-08-25 2019-03-05 湖南民康生物技术研究所 A kind of method of herbal prescription preparation prevention and treatment porcine hyperthermia drug

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
周文章等: "中西结合治疗猪喘气病", 《中兽医医药杂志》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112841433A (en) * 2020-12-31 2021-05-28 江西正邦动物保健品有限公司 Feeding composition for improving immunity of swinery and purifying vivotoxin and preparation method thereof

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