CN101934026B - Chinese medicinal composition for treating cough and asthma and preparation method thereof - Google Patents

Chinese medicinal composition for treating cough and asthma and preparation method thereof Download PDF

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CN101934026B
CN101934026B CN 201010297572 CN201010297572A CN101934026B CN 101934026 B CN101934026 B CN 101934026B CN 201010297572 CN201010297572 CN 201010297572 CN 201010297572 A CN201010297572 A CN 201010297572A CN 101934026 B CN101934026 B CN 101934026B
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cough
asthma
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chinese medicinal
medicinal composition
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CN101934026A (en
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曹利平
王菊
孙平川
郭颖娟
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Shaanxi Hantang Pharmaceutical Co ltd
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SHAANXI PROVINCE ACADEMY OF TRADITIONAL CHINESE MEDICINE HANTANG PHARMACEUTICAL CO Ltd
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Abstract

The invention discloses a Chinese medicinal composition for treating cough and asthma. The Chinese medicinal composition consists of the following raw materials in percentage by mass: 5 to 6 percent of prepared ephedra, 8 to 9 percent of apricot kernel, 8 to 9 percent of red tangerine peel, 5 to 6 percent of prepared pinellia tuber, 13 to 15 percent of tuckahoe, 13 to 15 percent of Zhejiang fritillary bulb, 13 to 15 percent of baical skullcap root, 13 to 15 percent of wax gourd seed, 9 to 10 percent of common coltsfoot flower and 5 to 6 percent of liquorice root. The invention also discloses a preparation method for the Chinese medicinal composition, which comprises the following steps of: extracting volatile oil from the weighed prepared ephedra, apricot kernel and red tangerine peel by adding water, and decocting the medicinal dregs and the prepared pinellia tuber, tuckahoe, baical skullcap root, wax gourd seed, common coltsfoot flower and liquorice root twice for 1 hour every time by adding water; combining the decoctions, filtering the decoction, and concentrating the filtrate to form thick paste with reduced pressure; and then crushing the Zhejiang fritillary bulb into fine powder, mixing the fine powder and the thick paste, drying the mixture under reduced pressure, and combining the dried mixture and the extracted volatile oil to obtain the Chinese medicinal composition. The Chinese medicinal composition can radically treat empirical cough and asthma, and also has the effect of supplementing insufficiency.

Description

A kind of Chinese medicine composition for the treatment of cough and asthma and preparation method thereof
Technical field
The invention belongs to technical field of Chinese medicines, relate to a kind of Chinese medicine composition for the treatment of cough and asthma, the invention still further relates to the preparation method of this Chinese medicine composition.
Background technology
Cough with asthma is the cardinal symptom of pneumonopathy.The cause of disease of cough with asthma has Exogenous and internal injuries not, and pathogenesis has dividing of cold and heat and asthenia and sthenia.Cough with asthma and expectorant are closely related, the every many folder expectorant of cough with asthma, and expectorant also often causes cough with asthma, and the relieving cough and asthma Apophlegmatisant is various clinically, but arranged dividing of cold and heat and asthenia and sthenia, uses cumbersome.
Cough with asthma is divided into excess syndrome and deficiency syndrome.It is sturdy that excess syndrome is more common in body constitution, being invaded by exogenous pathogen, and cough with asthma is from the beginning of, or the patient of chronic cough and asthma acute attack.With the cough sound pitch, it is thick to pant, or rale is arranged, or double exterior syndrome is characteristics.Cough has: cold-phlegm cough, cough due to damp-phlegm, cough due to fluid-retention, phlegm heat cough, dry stool phlegm cough, bloody sputum cough, pertinacious phlegm, old productive cough are coughed etc., all divide it with the characteristics of expectoration expectorant.Asthma then is two kinds of diseases, breathes heavily with breath speech, roar with sound speech, but clinical medication difference to asthma is little, so to breathe heavily opinion.The character of asthma also has cold and heat not.
The cough with asthma deficiency syndrome are more common in the chronic patient of prolonged illness asthenia, and with sound of cough being low and weak, the feeble QI of panting is characteristics.Deficiency syndrome are divided again: the deficiency of vital energy, the deficiency of YIN, yang deficiency, deficiency of both QI and YIN.
Actually mostly be due to the diseases caused by exogenous pathogenic factor, void is then many to be caused by internal injury.Cold-phlegm, damp-phlegm, phlegm retention and so on all belong to cold and cool property, and medication is all hot product; Heat-phlegm, dry phlegm, bloody sputum belong to excess-heat more, and medication mostly is cold and cool product.So when treatment, according to the state of an illness, distinguish the specimen emergency, make every effort to prevent and treat combination.Cough illness is repeatedly outbreak easily, and many courses of disease are touching, is difficult to speed more, for rooting is controlled, and necessary symptomatic treatment in acute condition, relieving the primary symptom in a chronic case, control combination.
The Chinese medicine composition of existing treatment excess syndrome cough with asthma can not be held concurrently and be treated the deficiency syndrome cough with asthma, and this just causes and uses cumbersomely, and radical cure time of getting up is long, is difficult to speed and heals.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicine composition for the treatment of cough and asthma, can effect a radical cure the cough and asthma of excess syndrome, also have the effect of tonify deficiency, and instant effect, do not recur.
Another object of the present invention provides the preparation method of the Chinese medicine composition of above-mentioned treatment cough and asthma.
The technical solution adopted in the present invention is that a kind of Chinese medicine composition for the treatment of cough and asthma is comprised of following raw material by mass percentage:
Herba Ephedrae (processed) 5%~6%, Semen Armeniacae Amarum 8%~9%, dried tangerine peel 8%~9%, Rhizoma Pinelliae Preparata 5%~6%, Poria 13%~15%, Bulbus Fritillariae Thunbergii 13%~15%, Radix Scutellariae 13%~15%, Semen Benincasae 13%~15%, Flos Farfarae 9%~10%, Radix Glycyrrhizae 5%~6%, the quality summation of above component is 100%.
Another technical scheme of the present invention is, the preparation method of the Chinese medicine composition of above-mentioned treatment cough and asthma is carried out according to the following steps:
Step 1,
According to mass percent, take by weighing respectively 5%~6% Herba Ephedrae (processed), 8%~9% Semen Armeniacae Amarum, 8%~9% dried tangerine peel, 5%~6% Rhizoma Pinelliae Preparata, 13%~15% Poria, 13%~15% Bulbus Fritillariae Thunbergii, 13%~15% Radix Scutellariae, 13%~15% Semen Benincasae, 9%~10% Flos Farfarae, 5%~6% Radix Glycyrrhizae, the quality summation of above component is 100%;
Step 2,
With step 1 claim Herba Ephedrae (processed), Semen Armeniacae Amarum and dried tangerine peel add suitable quantity of water and extract volatile oil, remaining medicinal residues and step 1 claim Rhizoma Pinelliae Preparata, Poria, Radix Scutellariae, Semen Benincasae, Flos Farfarae and Radix Glycyrrhizae together decoct with water each 1 hour 2 times; Collecting decoction filters, and filtrate decompression is condensed into thick paste, and temperature is 50 ℃-60 ℃ in the concentration process, and vacuum is 0.06 Mpa-0.07Mpa; Then step 1 is claimed Bulbus Fritillariae Thunbergii be ground into fine powder and mix with above-mentioned thick paste, drying under reduced pressure, temperature is 60 ℃-70 ℃, vacuum is 0.07 Mpa-0.08 Mpa, the volatile oil that the dry thing that makes and said extracted go out merges, and get final product.
The present invention is the Chinese medicine composition for the treatment of cough and asthma, good effect, instant effect, reasonable recipe.Herba Ephedrae (processed), Semen Armeniacae Amarum, the tangerine cold-phlegm cough with asthma that is used for; Rhizoma Pinelliae Preparata, Poria are used for the damp-phlegm cough with asthma; Bulbus Fritillariae Thunbergii, Radix Scutellariae, Semen Benincasae are used for the heat-phlegm cough with asthma; Flos Farfarae, Radix Glycyrrhizae are used for the deficiency-phlegm cough with asthma.Be mainly used in the cough with asthma of excess syndrome, but deficiency syndrome are also had the effect of tonify deficiency, the party is no matter be the cough with asthma that the cold-phlegm damp-phlegm is discussed warmly thus, or the deficiency syndrome cough with asthma all has good therapeutic effect.
The specific embodiment
The present invention is described in detail below in conjunction with the implementation example.
The present invention is the Chinese medicine composition for the treatment of cough and asthma, is comprised of following raw material by mass percentage:
Herba Ephedrae (processed) 5%~6%, Semen Armeniacae Amarum 8%~9%, dried tangerine peel 8%~9%, Rhizoma Pinelliae Preparata 5%~6%, Poria 13%~15%, Bulbus Fritillariae Thunbergii 13%~15%, Radix Scutellariae 13%~15%, Semen Benincasae 13%~15%, Flos Farfarae 9%~10%, Radix Glycyrrhizae 5%~6%, the quality summation of above component is 100%.
The present invention relates to treat the preparation method of cough and asthma Chinese medicine composition, specifically implement according to following steps:
Step 1,
According to mass percent, take by weighing respectively 5%~6% Herba Ephedrae (processed), 8%~9% Semen Armeniacae Amarum, 8%~9% dried tangerine peel, 5%~6% Rhizoma Pinelliae Preparata, 13%~15% Poria, 13%~15% Bulbus Fritillariae Thunbergii, 13%~15% Radix Scutellariae, 13%~15% Semen Benincasae, 9%~10% Flos Farfarae, 5%~6% Radix Glycyrrhizae, the quality summation of above component is 100%;
Step 2,
With step 1 claim Herba Ephedrae (processed), Semen Armeniacae Amarum and dried tangerine peel add suitable quantity of water and extract volatile oil, remaining medicinal residues and step 1 claim Rhizoma Pinelliae Preparata, Poria, Radix Scutellariae, Semen Benincasae, Flos Farfarae and Radix Glycyrrhizae together decoct with water each 1 hour 2 times; Collecting decoction filters, and filtrate decompression is condensed into thick paste, and temperature is 50 ℃-60 ℃ in the concentration process, and vacuum is 0.06 Mpa-0.07Mpa; Then step 1 is claimed Bulbus Fritillariae Thunbergii be ground into fine powder and mix with above-mentioned thick paste, drying under reduced pressure, temperature is 60 ℃-70 ℃, vacuum is 0.07 Mpa-0.08 Mpa, the volatile oil that the dry thing that makes and said extracted go out merges, and adds suitable excipient and makes other preparations such as tablet, buccal tablet, granule, capsule.
Usage and consumption: oral, each serving restraining one day 3 times with 1.5.
Points for attention: hypertension, cardiac use the careful usefulness of anemia of pregnant woman under the doctor instructs.
Effect and the function of each raw material in this medicine cures mainly:
Herba Ephedrae (processed): have lung moistening, relieving asthma, antitussive action.The multiplex card of breathing with cough of having separated in table disease.The property that the hot loose and little double hardship of this product is fallen, but the closing of external-open fur are so that lung qi a surname is smooth; In the gas of superinverse falls, with multiple lung department respectful fall normal, so kind relievining asthma for curing mainly the key medicine of breathing with cough due to the sluggishness of lung-QI, is monarch drug in the side.
Semen Armeniacae Amarum: bitter in the mouth, slightly warm in nature; Slightly poisonous.Return lung, large intestine channel.Has the sending down the abnormal ascending QI relieving cough and asthma, the effect of loosening bowel to relieve constipation.Be used for cough and asthma, the fullness in the chest abundant expectoration, blood deficiency Tianjin is withered, the dryness of the intestine constipation.Itself and Herba Ephedrae (processed) one a surname one fall, and cooperatively interact, and the depressed lung-energy dispersing cough-relieving is monarch drug altogether.
Tangerine: acrid in the mouth, hardship, warm in nature.Return lung, spleen channel.Cold expelling, dampness, promoting the circulation of QI, the effect of expectorant.Be used for the cough due to wind and cold, the itching of the throat abundant expectoration, food stagnation is got sick from drinking too much wine, and the vomiting and nausea painful abdominal mass is vexed.
Rhizoma Pinelliae Preparata: warm in nature, acrid in the mouth belongs to product on the eliminating phlegm and lowering adverse QI.Has drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, the effect of eliminating stagnation expectorant.
Bulbus Fritillariae Thunbergii: bitter in the mouth cold in nature, return lung, heart channel.Has the heat clearing away eliminating stagnation, preventing phlegm from forming and stopping coughing.Be used for wind-heat invading the lung, phlegm-fire cough, lung abscess, acute mastitis, scrofula, sore.
Semen Benincasae: lung moistening, reduce phlegm eliminating carbuncle, diuretic.Has removing heat from the lung and dissipating phlegm, the effect of promoting diuresis and pus discharge.Be used for controlling phlegm-heat cough, lung abscess, acute appendicitis, leukorrhagia, nebulousurine etc.
Flos Farfarae: the little hardship of acrid in the mouth, warm in nature.Return lung meridian.Has nourishing the lung to keep the adverse QI downward, the effect of relieving cough and resolving phlegm.Being used for new chronic cough coughs; Asthma; The chronic cough hemoptysis.
Above dried tangerine peel, Rhizoma Pinelliae Preparata, Bulbus Fritillariae Thunbergii, stir-fry Semen Benincasae, Flos Farfarae preventing phlegm from forming and stopping coughing are ministerial drug altogether.Wherein dried tangerine peel is apt to control the cold-phlegm cough with asthma, the kind damp-phlegm cough with asthma of controlling of Rhizoma Pinelliae Preparata, and Bulbus Fritillariae Thunbergii, Semen Benincasae are apt to control the heat-phlegm cough with asthma, and Flos Farfarae is controlled new and old various cough and asthma, especially is apt to control the bloody sputum cough with asthma.
Poria: sweet in the mouth, light, property is flat.GUIXIN, lung, spleen, kidney channel.Have the promoting diuresis to eliminate damp pathogen effect and be used for edema oliguria, phlegm retention vertigo and palpitation.
Radix Scutellariae: bitter in the mouth is cold in nature.Return lung, spleen, gallbladder, large intestine, small intestine meridian.Have clearing away damp-heat, pathogenic fire purging, detoxifcation, hemostasis, antiabortive, be used for the damp-warm diseases heating, cough due to lung-heat, pneumonia, spitting of blood, jaundice, damp-heat dysentery, conjunctival congestion and swelling pain, frequent fetal movement, vascular hypertension, carbuncle sore tumefacting virus.
Poria and Radix Scutellariae in the side are all adjuvant drug, and the Radix Scutellariae clearing away lung-heat is assisted a ruler in governing a country the merit of Bulbus Fritillariae Thunbergii and Semen Benincasae heat clearing and damp drying, moistening the lung and resolving phlegm; The Poria promoting diuresis to eliminate damp pathogen is assisted a ruler in governing a country the Rhizoma Pinelliae Preparata lowering the adverse-rising QI and eliminating phlegm, and one separates the cough with asthma that phlegm retention checks.
Radix Glycyrrhizae: sweet in the mouth is flat.GUIXIN, lung, spleen, stomach warp.Has expelling phlegm for arresting cough, relieving spasm to stop pain, the effect of coordinating the actions of various ingredients in a prescription.Be used for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, emergency drug toxicity, strong.The effect of its existing expelling phlegm for arresting cough in the side, the while carries on a shoulder pole again coordinating the actions of various ingredients in a prescription, relaxes the merit of the property of medicine, for making medicine.
Cough illness has dividing of deficiency and excess, actually mostly is due to the diseases caused by exogenous pathogenic factor, and void is then many to be caused by internal injury.Excess syndrome has again dividing of cold and heat damp-phlegm, and we are exactly in this dialectical situation, reasonable formula, Herba Ephedrae (processed), Semen Armeniacae Amarum, the tangerine cold-phlegm cough with asthma that is used for; Rhizoma Pinelliae Preparata, Poria are used for the damp-phlegm cough with asthma; Bulbus Fritillariae Thunbergii, Radix Scutellariae, Semen Benincasae are used for the heat-phlegm cough with asthma; Flos Farfarae, Radix Glycyrrhizae are used for the deficiency-phlegm cough with asthma.Pharmaceutical composition of the present invention has depressed lung-energy dispersing, and the effect of relieving cough and resolving phlegm is used for the rear expectoration of flu, abundant expectoration, rough and acute/chronic bronchitis uncomfortable in chest.Be mainly used in the cough with asthma of excess syndrome, but deficiency syndrome are also had the effect of tonify deficiency, the party is no matter be the cough with asthma that the cold-phlegm damp-phlegm is discussed warmly thus, or the deficiency syndrome cough with asthma all has good therapeutic effect.
Pharmacodynamic experiment:
1. antiasthmatic effect: the Chinese medicine composition that makes by the inventive method is prepared into capsule, to the Cavia porcellus gastric infusion, can prolong the Experimental Asthma In Guinea-pigs incubation period that acetylcholine and histamine bring out by 3,6,9/kg.Illustrate that this medicine has obvious inhibitory action to the Experimental Asthma In Guinea-pigs that acetylcholine and histamine bring out.
2. preventing phlegm from forming and stopping coughing effect: the Chinese medicine composition that makes by the inventive method is prepared into capsule, press 3,6,9/kg to the mouse stomach administration, can prolong the mouse cough incubation period that strong aqua ammonia and sulfur dioxide bring out, reduce the cough number of times, the phenol red excretion amount of mice trachea is obviously increased.Illustrate that this medicine is to SO 2The cough of induced mice has obvious inhibitory action, and good phlegm-dispelling functions is arranged.
Acute toxicity test:
Select 60 of body weight 20-24g mices, male and female half and half are divided into 3 groups at random, and 20 every group, all fasting 16 h(can't help water) after, the disposable gavage of Chinese medicine composition of the present invention (being mixed with solution) given morning next day.Experiment I group is given this asthmatic medicament solution of 0.6825 g/ml, is equivalent to 20 times of people's consumptions by 20 ml/kg() gavage; Experiment II group is equivalent to 40 times of people's consumptions to this asthmatic medicament solution of 0.6825g/ml by 40 ml/kg() gavage; Experiment III group is equivalent to 80 times of people's consumptions for this asthmatic medicament solution of 0.6825 g/ml 80 ml/kg() gavage.Observe immediately the reaction of animals situation after giving tested medicine, observe every day 2 times, Continuous Observation 7 d record the mice response situation day by day.
The result to the tested medicine of animal after, tightly observed in 7 d, animal appearance, behavioral activity, the mental status, appetite (feed consumption), defecation and color, fur and the colour of skin all change without unusual, breathe no abnormality seen, nose, eye, oral cavity be all without unusual secretions, and none is dead and poison in 3 groups 60 mice 7 d.According to statistics Wrightization method, existing assurance more than 99.99% proves that the half of mice oral administration causes mortality must be greater than 80 times of the positive usual amounts of people, and the safety of prompting oral medication is large.Therefore think that this law preparation toxicity is very low, the clinical medicine dose of recommending is safe.
Case one
Xi'an Changan District Zhang, woman, 58 years old.Suffered from cough illness more than 5 years.Whenever winter, cough and asthma is serious in going out, and all must wear masks in the activity of own home courtyard.Cough is got up out of breath, abundant expectoration, the quite severity of asthma, the easily enuresis.Take this medicine after 1 week, the cough number of times reduces, and asthma is so unobvious yet, adheres to again taking for 1 week, and disease is fully recovered.
Case two
The Xi'an poplar, man, 70 years old.Suffered from cough illness 25 years, the cough with copious phlegm of smoking and too much causing at an early age, asthma, the companion coughs up white mucus expectorant, and idol has yellowish purulent sputum, cough aggravation in early morning.Once be diagnosed as bronchial asthma, bronchitis, interstitial pneumonia etc.Though through the treatment remission.But attack times increases year by year, use this medicine after, cough is clearly better, the morbidity number of times reduces, each morbidity, 1 week of taking medicine obviously takes a turn for the better.
Embodiment 1
According to mass percent, take by weighing respectively 5% Herba Ephedrae (processed), 8% Semen Armeniacae Amarum, 8% dried tangerine peel, 5% Rhizoma Pinelliae Preparata, 15% Poria, 15% Bulbus Fritillariae Thunbergii, 15% Radix Scutellariae, 15% Semen Benincasae, 9% Flos Farfarae, 5% Radix Glycyrrhizae; With claim Herba Ephedrae (processed), Semen Armeniacae Amarum and dried tangerine peel add suitable quantity of water and extract volatile oil, remaining medicinal residues with claim Rhizoma Pinelliae Preparata, Poria, Radix Scutellariae, Semen Benincasae, Flos Farfarae and Radix Glycyrrhizae together decoct with water each 1 hour 2 times; Collecting decoction filters, and filtrate decompression is condensed into thick paste, and temperature is 50 ℃-60 ℃ in the concentration process, and vacuum is 0.06 Mpa-0.07Mpa; Then step 1 is claimed Bulbus Fritillariae Thunbergii be ground into fine powder and mix with above-mentioned thick paste, drying under reduced pressure, temperature is 60 ℃-70 ℃, vacuum is 0.07 Mpa-0.08 Mpa, the volatile oil that the dry thing that makes and said extracted go out merges, and namely makes.
Embodiment 2
According to mass percent, take by weighing respectively 6% Herba Ephedrae (processed), 9% Semen Armeniacae Amarum, 9% dried tangerine peel, 6% Rhizoma Pinelliae Preparata, 15% Poria, 13% Bulbus Fritillariae Thunbergii, 13% Radix Scutellariae, 13% Semen Benincasae, 10% Flos Farfarae, 6% Radix Glycyrrhizae; With claim Herba Ephedrae (processed), Semen Armeniacae Amarum and dried tangerine peel add suitable quantity of water and extract volatile oil, remaining medicinal residues with claim Rhizoma Pinelliae Preparata, Poria, Radix Scutellariae, Semen Benincasae, Flos Farfarae and Radix Glycyrrhizae together decoct with water each 1 hour 2 times; Collecting decoction filters, and filtrate decompression is condensed into thick paste, and temperature is 50 ℃-60 ℃ in the concentration process, and vacuum is 0.06 Mpa-0.07Mpa; Then step 1 is claimed Bulbus Fritillariae Thunbergii be ground into fine powder and mix with above-mentioned thick paste, drying under reduced pressure, temperature is 60 ℃-70 ℃, vacuum is 0.07 Mpa-0.08 Mpa, the volatile oil that the dry thing that makes and said extracted go out merges, and namely makes.
Embodiment 3
According to mass percent, take by weighing respectively 6% Herba Ephedrae (processed), 9% Semen Armeniacae Amarum, 9% dried tangerine peel, 6% Rhizoma Pinelliae Preparata, 13% Poria, 14% Bulbus Fritillariae Thunbergii, 14% Radix Scutellariae, 14% Semen Benincasae, 9.5% Flos Farfarae, 5.5% Radix Glycyrrhizae; With claim Herba Ephedrae (processed), Semen Armeniacae Amarum and dried tangerine peel add suitable quantity of water and extract volatile oil, remaining medicinal residues with claim Rhizoma Pinelliae Preparata, Poria, Radix Scutellariae, Semen Benincasae, Flos Farfarae and Radix Glycyrrhizae together decoct with water each 1 hour 2 times; Collecting decoction filters, and filtrate decompression is condensed into thick paste, and temperature is 50 ℃-60 ℃ in the concentration process, and vacuum is 0.06 Mpa-0.07Mpa; Then step 1 is claimed Bulbus Fritillariae Thunbergii be ground into fine powder and mix with above-mentioned thick paste, drying under reduced pressure, temperature is 60 ℃-70 ℃, vacuum is 0.07 Mpa-0.08 Mpa, the volatile oil that the dry thing that makes and said extracted go out merges, and namely makes.
Embodiment 4
According to mass percent, take by weighing respectively 5.5% Herba Ephedrae (processed), 8.5% Semen Armeniacae Amarum, 8.5% dried tangerine peel, 5.5% Rhizoma Pinelliae Preparata, 14% Poria, 14% Bulbus Fritillariae Thunbergii, 15% Radix Scutellariae, 15% Semen Benincasae, 9% Flos Farfarae, 5% Radix Glycyrrhizae; With claim Herba Ephedrae (processed), Semen Armeniacae Amarum and dried tangerine peel add suitable quantity of water and extract volatile oil, remaining medicinal residues with claim Rhizoma Pinelliae Preparata, Poria, Radix Scutellariae, Semen Benincasae, Flos Farfarae and Radix Glycyrrhizae together decoct with water each 1 hour 2 times; Collecting decoction filters, and filtrate decompression is condensed into thick paste, and temperature is 50 ℃-60 ℃ in the concentration process, and vacuum is 0.06 Mpa-0.07Mpa; Then step 1 is claimed Bulbus Fritillariae Thunbergii be ground into fine powder and mix with above-mentioned thick paste, drying under reduced pressure, temperature is 60 ℃-70 ℃, vacuum is 0.07 Mpa-0.08 Mpa, the volatile oil that the dry thing that makes and said extracted go out merges, and namely makes.

Claims (2)

1. Chinese medicine composition for the treatment of cough and asthma is comprised of following raw material by mass percentage:
Herba Ephedrae (processed) 5%~6%, Semen Armeniacae Amarum 8%~9%, dried tangerine peel 8%~9%, Rhizoma Pinelliae Preparata 5%~6%, Poria 13%~15%, Bulbus Fritillariae Thunbergii 13%~15%, Radix Scutellariae 13%~15%, Semen Benincasae 13%~15%, Flos Farfarae 9%~10%, Radix Glycyrrhizae 5%~6%, the quality summation of above component is 100%.
2. preparation method for the treatment of the Chinese medicine composition of cough and asthma, specifically implement according to following steps:
Step 1,
According to mass percent, take by weighing respectively 5%~6% Herba Ephedrae (processed), 8%~9% Semen Armeniacae Amarum, 8%~9% dried tangerine peel, 5%~6% Rhizoma Pinelliae Preparata, 13%~15% Poria, 13%~15% Bulbus Fritillariae Thunbergii, 13%~15% Radix Scutellariae, 13%~15% Semen Benincasae, 9%~10% Flos Farfarae, 5%~6% Radix Glycyrrhizae, the quality summation of above component is 100%;
Step 2,
With step 1 claim Herba Ephedrae (processed), Semen Armeniacae Amarum and dried tangerine peel add suitable quantity of water and extract volatile oil, remaining medicinal residues and step 1 claim Rhizoma Pinelliae Preparata, Poria, Radix Scutellariae, Semen Benincasae, Flos Farfarae and Radix Glycyrrhizae together decoct with water each 1 hour 2 times; Collecting decoction filters, and filtrate decompression is condensed into thick paste, and temperature is 50 ℃-60 ℃ in the concentration process, and vacuum is 0.06 Mpa-0.07Mpa; Then step 1 is claimed Bulbus Fritillariae Thunbergii be ground into fine powder and mix with above-mentioned thick paste, drying under reduced pressure, temperature is 60 ℃-70 ℃, vacuum is 0.07 Mpa-0.08 Mpa, the volatile oil that the dry thing that makes and said extracted go out merges, and get final product.
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