CN113713044B - Traditional Chinese medicine composition for treating chronic atrophic gastritis, preparation method and application - Google Patents

Traditional Chinese medicine composition for treating chronic atrophic gastritis, preparation method and application Download PDF

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CN113713044B
CN113713044B CN202110892098.6A CN202110892098A CN113713044B CN 113713044 B CN113713044 B CN 113713044B CN 202110892098 A CN202110892098 A CN 202110892098A CN 113713044 B CN113713044 B CN 113713044B
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atrophic gastritis
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王宗明
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Abstract

The invention relates to a traditional Chinese medicine composition for treating chronic atrophic gastritis, a preparation method and application thereof, belonging to the technical field of traditional Chinese medicine preparations. The traditional Chinese medicine composition for treating chronic atrophic gastritis is prepared from the following raw materials in parts by weight: 14-16 parts of prepared rehmannia root, 18-22 parts of cuttlebone, 7-11 parts of adenophora stricta, 14-16 parts of radix ophiopogonis, 8-10 parts of dogwood, 14-16 parts of white paeony root, 7-11 parts of codonopsis pilosula, 10-14 parts of bighead atractylodes rhizome, 28-32 parts of fructus cannabis, 18-22 parts of platycladi seed, 14-16 parts of spina date seed, 8-10 parts of radix polygonati officinalis, 4-8 parts of honey-fried licorice root, 7-11 parts of pseudo-ginseng, 8-12 parts of tortoise plastron and 4-6 parts of rhizoma anemarrhenae. The invention also discloses a preparation method and application of the traditional Chinese medicine composition for treating chronic atrophic gastritis. The traditional Chinese medicine composition for treating chronic atrophic gastritis has the effects of strengthening spleen, tonifying qi, removing blood stasis, detoxifying, nourishing stomach and harmonizing stomach, and can be used for treating atrophic gastritis.

Description

Traditional Chinese medicine composition for treating chronic atrophic gastritis, preparation method and application
Technical Field
The invention relates to a traditional Chinese medicine composition for treating chronic atrophic gastritis, a preparation method and application thereof, belonging to the technical field of traditional Chinese medicine preparations.
Background
Chronic Atrophic Gastritis (CAG) is a Chronic disease characterized by atrophy of gastric mucosal epithelium and glands, thinning of mucosa, thickening of mucosal muscularis, and multiple accompanying intestinal glandular metaplasia, atypical hyperplasia. Clinically, it is manifested as fullness and distention in the stomach, pain, anorexia, belching, acid regurgitation, etc., and it belongs to the category of "fullness and distention in the stomach" and "epigastric pain" in traditional Chinese medicine.
Chronic atrophic gastritis is characterized pathologically by atrophy of glands and thinning of mucosa, as in soil desertification, with consequent infiltration of lymphocytes, plasma cells and neutrophils, which we can compare to gastric mucosa desertification. When the soil is desertified, the plants cannot grow, and the gastric mucosa cannot perform the acquired functions.
At present, no specific therapy for chronic atrophic gastritis exists in western medicine, the treatment aims at eradicating helicobacter pylori, protecting gastric mucosa, promoting gastric motility (such as domperidone), supplementing mucosal nutrition (such as vitamine) and the like, the curative effect is poor, the recurrence rate is high, and the chronic atrophic gastritis is difficult to cure. Although the traditional Chinese medicine has obvious curative effect, the treatment methods are different, the prescriptions and the medicines are different, and a unified, normative and standard treatment scheme is lacked.
In summary, there is a need to develop a new Chinese medicinal composition for treating chronic atrophic gastritis, a preparation method and an application thereof, so as to overcome the above drawbacks.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine composition for treating chronic atrophic gastritis.
The technical scheme for solving the technical problems is as follows: a traditional Chinese medicine composition for treating chronic atrophic gastritis is prepared from the following raw materials in parts by weight: 14-16 parts of prepared rehmannia root, 18-22 parts of cuttlebone, 7-11 parts of adenophora stricta, 14-16 parts of radix ophiopogonis, 8-10 parts of dogwood, 14-16 parts of white paeony root, 7-11 parts of codonopsis pilosula, 10-14 parts of bighead atractylodes rhizome, 28-32 parts of fructus cannabis, 18-22 parts of platycladi seed, 14-16 parts of spina date seed, 8-10 parts of radix polygonati officinalis, 4-8 parts of honey-fried licorice root, 7-11 parts of pseudo-ginseng, 8-12 parts of tortoise plastron and 4-6 parts of rhizoma anemarrhenae.
The traditional Chinese medicine prescription:
prepared rehmannia root, radix rehmanniae Praeparata, sweet in taste, warm in nature, enters liver and kidney meridians and has the effects of nourishing yin and enriching blood.
Cuttlebone, salty and astringent in taste, warm in nature, entering spleen and kidney meridians, has the actions of astringing to stop bleeding, astringing essence to stop leucorrhea, relieving hyperacidity and pain, astringing dampness and healing wound.
The root of straight ladybell, sweet in taste, slightly bitter in flavor and slightly cold in nature, enters lung and stomach channels and has the effects of nourishing yin, clearing heat, moistening lung, reducing phlegm, benefiting stomach and promoting fluid production.
Ophiopogon root, radix Ophiopogonis is sweet in taste, slightly bitter in flavor and slightly cold in nature, enters lung, heart and stomach channels, and has the effects of nourishing yin, moistening lung, benefiting stomach, promoting fluid production, clearing heart fire and relieving restlessness.
Dogwood, fructus Corni, with sour and astringent taste and warm nature, enters liver and kidney meridians and has the effects of tonifying liver and kidney, astringing and relieving depletion.
White peony root, radix Paeoniae alba, bitter and sour in taste, slightly cold in nature, enters liver and spleen meridians, and has the effects of nourishing blood, astringing yin, softening liver, relieving pain, and calming liver yang.
Codonopsis pilosula is sweet in taste and neutral in nature, and has the effects of tonifying middle-jiao, Qi and promoting the production of body fluid, and the codonopsis pilosula enters spleen and lung channels.
The white atractylodes rhizome is bitter and sweet in taste and warm in nature, and has the effects of tonifying spleen and qi, eliminating dampness and promoting diuresis, arresting sweating and preventing miscarriage, and the white atractylodes rhizome enters spleen and stomach channels.
Fructus cannabis, sweet in taste, neutral in nature, enters spleen and large intestine channels and has the effect of relaxing bowel.
Baizi ren, sweet in flavor, neutral in nature, entering heart, kidney and large intestine meridians, nourishing heart to calm mind, moistening intestines to relieve constipation, checking sweating
The spina date seed is sweet and sour in taste and neutral in nature, enters liver, gallbladder and heart channels, and has the effects of nourishing heart and liver, calming heart and soothing nerves, arresting sweating and promoting fluid production.
Yu Zhu is sweet in flavor and neutral in nature, enters lung and stomach meridians, and has the effects of nourishing yin, moistening dryness, promoting the production of body fluid and quenching thirst.
Prepared licorice, baked with honey, has the functions of nourishing yin and blood, warm nature and sweet taste, enters heart, lung, stomach and spleen channels, and has the functions of invigorating spleen and stomach, benefiting qi and restoring pulse.
Notoginseng radix, sweet in taste, slightly bitter in flavor, warm in nature, and has effects of dispersing blood stasis, stopping bleeding, relieving swelling and pain, and entering heart, liver and spleen channels.
Tortoise plastron, sweet in taste, salty and cold in nature, enters liver, kidney and heart channels, and has the effects of nourishing yin, suppressing yang, tonifying kidney, strengthening bone, nourishing blood and tonifying heart.
Anemarrhena asphodeloides Bunge, bitter and sweet in taste, cold in nature, enters lung, stomach and kidney meridians, and has the effects of clearing heat and purging fire, nourishing yin and moistening dryness.
The traditional Chinese medicine composition is from clinical empirical formula, and the theoretical basis is thought. According to the theory of the "Nei Jing", the pathological condition of chronic atrophic gastritis is similar to soil desertification, which is usually due to yin deficiency. The Chinese Cheng is as said in Cheng Ji Shi (Ready to read): all normal qi of all people is inherited from stomach, and fluids in stomach are withered, so viscera lose their moistening and moistening effects. Therefore, a sweet, cold and moist food is drunk into the stomach to recover yin, naturally transport essence to spleen, distribute essence by spleen qi, transport essence to lung, regulate water passage, transport bladder downward, and transport parallel five channels, and promote body fluid generation to recover ear. The pathological condition of the chronic atrophic gastritis is similar to the natural desertification of soil, and water is needed to moisten the sand, wood is used to fix the sand, and soil is used to mix the sand to control the desertification of the soil. Meanwhile, atrophic mucosa is required to solve the problem of blood supply and the problems of erosion and intestinal metaplasia after atrophy. In the formula, prepared rehmannia root is sweet and warm to enrich the blood and nourish yin and replenish essence and marrow to achieve the effect of replenishing water, cuttlebone is salty and warm to enter the kidney to assist the prepared rehmannia root to nourish the kidney water, and sweet to replenish soil to achieve the effect of combining water and soil. The traditional Chinese medicine seven emotions, which are mutually reinforced as miraculous, are added with the root of straight ladybell and the dwarf lilyturf root which are sweet and slightly cold to nourish stomach yin and assist the prepared rhizome of rehmannia and the cuttlebone to replenish water and moisten sand. Cornus officinalis and paeonia lactiflora are used for entering the liver to nourish the liver and achieve the effect of fixing sand. The codonopsis pilosula, the bighead atractylodes rhizome and the rock candy are sweet and have the functions of invigorating qi and regulating the flow of qi in spleen and stomach. Yu Zhu is added to treat the disease because yin deficiency can easily generate internal heat. For water exhaustion in stomach, intestine dryness is easy to constipation, water is insufficient, heart spirit is easy to be deprived of nourishment to cause insomnia, so hemp fruit and arborvitae seed are used for moistening intestine, spina date seed is used for nourishing blood, tortoise plastron is used for softening hard masses, and rhizoma anemarrhenae is used for lowering fire to restrict fire caused by yin deficiency. In a word, when the soil is dry, water is supplemented, wood is supported, and the soil is mixed, so that the purpose of treating the atrophic gastritis is achieved. In the prior art, no report is made on the combination of prepared rehmannia root, cuttlebone, adenophora stricta, dwarf lilyturf tuber, dogwood, white paeony root, codonopsis pilosula, bighead atractylodes rhizome, fructus cannabis, platycladi seed, spina date seed, fragrant solomonseal rhizome, honey-fried licorice root, pseudo-ginseng, tortoise plastron and rhizoma anemarrhenae for treating chronic atrophic gastritis. Through a large number of experiments, the inventor of the application surprisingly and unexpectedly discovers that the effects of strengthening spleen and replenishing qi, removing blood stasis and detoxifying, and nourishing stomach and stomach can be achieved by combining the raw materials, and the traditional Chinese medicine composition can be used for treating atrophic gastritis.
The traditional Chinese medicine composition for treating chronic atrophic gastritis has the beneficial effects that:
1. the traditional Chinese medicine composition for treating chronic atrophic gastritis has the effects of strengthening spleen, tonifying qi, removing blood stasis, detoxifying, nourishing stomach and harmonizing stomach, and can be used for treating atrophic gastritis.
2. The traditional Chinese medicine composition for treating chronic atrophic gastritis does not have any toxic or side effect, has an obvious curative effect, and does not relapse after medicine withdrawal.
On the basis of the technical scheme, the invention can be improved as follows.
Further, the feed is prepared from the following raw materials in parts by weight: 14 parts of prepared rehmannia root, 22 parts of cuttlebone, 7 parts of adenophora stricta, 16 parts of dwarf lilyturf tuber, 8 parts of dogwood, 16 parts of white paeony root, 7 parts of codonopsis pilosula, 14 parts of bighead atractylodes rhizome, 28 parts of fructus cannabis, 22 parts of platycladi seed, 14 parts of spina date seed, 10 parts of polygonatum odoratum, 4 parts of honey-fried licorice root, 11 parts of pseudo-ginseng, 8 parts of tortoise plastron and 6 parts of rhizoma anemarrhenae.
The adoption of the further beneficial effects is as follows: the above parameters are the best parameters, and the obtained traditional Chinese medicine composition has the best performance.
Further, the feed is prepared from the following raw materials in parts by weight: 15 parts of prepared rehmannia root, 20 parts of cuttlebone, 9 parts of adenophora stricta, 15 parts of radix ophiopogonis, 9 parts of dogwood, 15 parts of white paeony root, 9 parts of codonopsis pilosula, 12 parts of bighead atractylodes rhizome, 30 parts of fructus cannabis, 20 parts of platycladi seed, 15 parts of spina date seed, 9 parts of radix polygonati officinalis, 6 parts of honey-fried licorice root, 9 parts of pseudo-ginseng, 10 parts of tortoise plastron and 5 parts of rhizoma anemarrhenae.
The adoption of the further beneficial effects is as follows: the above parameters are the best parameters, and the obtained traditional Chinese medicine composition has the best performance.
Further, the feed is prepared from the following raw materials in parts by weight: 16 parts of prepared rehmannia root, 18 parts of cuttlebone, 11 parts of adenophora stricta, 14 parts of dwarf lilyturf tuber, 10 parts of dogwood, 14 parts of white paeony root, 11 parts of codonopsis pilosula, 10 parts of bighead atractylodes rhizome, 32 parts of fructus cannabis, 18 parts of platycladi seed, 16 parts of spina date seed, 8 parts of polygonatum odoratum, 8 parts of honey-fried licorice root, 7 parts of pseudo-ginseng, 12 parts of tortoise plastron and 4 parts of rhizoma anemarrhenae.
The adoption of the further beneficial effects is as follows: the above parameters are the best parameters, and the obtained traditional Chinese medicine composition has the best performance.
The second object of the present invention is to provide a method for preparing the above-mentioned Chinese medicinal composition for treating chronic atrophic gastritis.
The technical scheme for solving the technical problems is as follows: the preparation method of the traditional Chinese medicine composition for treating chronic atrophic gastritis comprises the following steps:
respectively weighing the following raw materials in parts by weight: 14-16 parts of prepared rehmannia root, 18-22 parts of cuttlebone, 7-11 parts of adenophora stricta, 14-16 parts of radix ophiopogonis, 8-10 parts of dogwood, 14-16 parts of white paeony root, 7-11 parts of codonopsis pilosula, 10-14 parts of bighead atractylodes rhizome, 28-32 parts of fructus cannabis, 18-22 parts of platycladi seed, 14-16 parts of spina date seed, 8-10 parts of radix polygonati officinalis, 4-8 parts of honey-fried licorice root, 7-11 parts of pseudo-ginseng, 8-12 parts of tortoise plastron and 4-6 parts of rhizoma anemarrhenae, which are respectively crushed, sieved and then uniformly mixed to obtain the traditional Chinese medicine composition for treating chronic atrophic gastritis.
The raw materials are all qualified products of traditional Chinese medicine decoction pieces. The sieving is to pass through a sieve of 80-100 meshes.
The preparation method of the traditional Chinese medicine composition for treating chronic atrophic gastritis has the following beneficial effects:
the traditional Chinese medicine composition for treating chronic atrophic gastritis has the advantages of simple preparation method, easy operation and low cost, and is suitable for large-scale popularization and application.
The third purpose of the invention is to provide the application of the traditional Chinese medicine composition for treating chronic atrophic gastritis.
The technical scheme for solving the technical problems is as follows: the traditional Chinese medicine composition for treating chronic atrophic gastritis is used alone or as an active component in the preparation of medicines for treating chronic atrophic gastritis.
The application of the traditional Chinese medicine composition for treating chronic atrophic gastritis has the following beneficial effects:
the traditional Chinese medicine composition for treating chronic atrophic gastritis can be used alone or used as an active component for preparing a medicine for treating chronic atrophic gastritis, and develops a new application.
The fourth purpose of the invention is to provide a medicine for treating chronic atrophic gastritis.
The technical scheme for solving the technical problems is as follows: a medicine for treating chronic atrophic gastritis is prepared by adding one or more pharmaceutically acceptable adjuvants into the above traditional Chinese medicine composition for treating chronic atrophic gastritis, and making into watered pill, granule, tablet or capsule by conventional process.
The medicine for treating chronic atrophic gastritis has the beneficial effects that:
the traditional Chinese medicine composition for treating chronic atrophic gastritis can be added with pharmaceutically acceptable auxiliary materials to prepare various dosage forms of medicines for treating chronic atrophic gastritis, and is convenient for patients to take medicines according to the state of illness.
On the basis of the technical scheme, the invention can be improved as follows.
Further, the auxiliary materials comprise any one or more of starch, microcrystalline cellulose, cocoa butter, carbomer, sodium benzoate, poloxamer and benzalkonium bromide.
Detailed Description
The principles and features of this invention are described below in conjunction with embodiments, which are included to explain the invention and not to limit the scope of the invention.
Example 1
The traditional Chinese medicine composition for treating chronic atrophic gastritis is prepared from the following raw materials by weight: 14g of prepared rehmannia root, 22g of cuttlebone, 7g of adenophora stricta, 16g of dwarf lilyturf tuber, 8g of dogwood, 16g of white paeony root, 7g of codonopsis pilosula, 14g of largehead atractylodes rhizome, 28g of fructus cannabis, 22g of platycladi seed, 14g of spina date seed, 10g of fragrant solomonseal rhizome, 4g of honey-fried licorice root, 11g of pseudo-ginseng, 8g of tortoise plastron and 6g of rhizoma anemarrhenae.
The preparation method of the traditional Chinese medicine composition for treating chronic atrophic gastritis comprises the following steps:
respectively weighing the following raw materials by weight: 14g of prepared rehmannia root, 22g of cuttlebone, 7g of adenophora stricta, 16g of dwarf lilyturf tuber, 8g of dogwood, 16g of white paeony root, 7g of codonopsis pilosula, 14g of largehead atractylodes rhizome, 28g of fructus cannabis, 22g of platycladi seed, 14g of spina date seed, 10g of fragrant solomonseal rhizome, 4g of honey-fried licorice root, 11g of pseudo-ginseng, 8g of tortoise plastron and 6g of rhizoma anemarrhenae, which are respectively crushed and sieved by a 100-mesh sieve, and then are uniformly mixed to obtain the traditional Chinese medicine composition for treating chronic atrophic gastritis.
The traditional Chinese medicine composition for treating chronic atrophic gastritis is used alone or as an active component in the preparation of medicines for treating chronic atrophic gastritis.
A Chinese medicinal composition for treating chronic atrophic gastritis is prepared by making into pill with cold boiled water or succus Zingiberis recens, drying at low temperature, testing quality, and packaging to obtain watered pill.
Example 2
The traditional Chinese medicine composition for treating chronic atrophic gastritis is prepared from the following raw materials by weight: 15g of prepared rehmannia root, 20g of cuttlebone, 9g of adenophora stricta, 15g of dwarf lilyturf tuber, 9g of dogwood, 15g of white paeony root, 9g of codonopsis pilosula, 12g of bighead atractylodes rhizome, 30g of fructus cannabis, 20g of platycladi seed, 15g of spina date seed, 9g of polygonatum odoratum, 6g of honey-fried licorice root, 9g of pseudo-ginseng, 10g of tortoise plastron and 5g of rhizoma anemarrhenae.
The preparation method of the traditional Chinese medicine composition for treating chronic atrophic gastritis comprises the following steps:
respectively weighing the following raw materials by weight: 15g of prepared rehmannia root, 20g of cuttlebone, 9g of adenophora stricta, 15g of radix ophiopogonis, 9g of dogwood, 15g of white paeony root, 9g of codonopsis pilosula, 12g of bighead atractylodes rhizome, 30g of fructus cannabis, 20g of platycladi seed, 15g of spina date seed, 9g of polygonatum odoratum, 6g of honey-fried licorice root, 9g of pseudo-ginseng, 10g of tortoise plastron and 5g of rhizoma anemarrhenae, and the raw materials are respectively crushed and sieved by a 100-mesh sieve and then uniformly mixed to obtain the traditional Chinese medicine composition for treating chronic atrophic gastritis.
The traditional Chinese medicine composition for treating chronic atrophic gastritis is used alone or as an active component in the preparation of medicines for treating chronic atrophic gastritis.
A medicine for treating chronic atrophic gastritis is prepared by adding one or more pharmaceutically acceptable adjuvants into the above traditional Chinese medicine composition for treating chronic atrophic gastritis, wherein the adjuvants comprise one or more of starch, microcrystalline cellulose, cacao butter, carbomer, sodium benzoate, poloxamer and benzalkonium bromide, and making into granule by conventional process.
Example 3
The traditional Chinese medicine composition for treating chronic atrophic gastritis is prepared from the following raw materials by weight: 16g of prepared rehmannia root, 18g of cuttlebone, 11g of adenophora stricta, 14g of dwarf lilyturf tuber, 10g of dogwood, 14g of white paeony root, 11g of codonopsis pilosula, 10g of largehead atractylodes rhizome, 32g of fructus cannabis, 18g of platycladi seed, 16g of spina date seed, 8g of fragrant solomonseal rhizome, 8g of honey-fried licorice root, 7g of pseudo-ginseng, 12g of tortoise plastron and 4g of rhizoma anemarrhenae.
The preparation method of the traditional Chinese medicine composition for treating chronic atrophic gastritis comprises the following steps:
respectively weighing the following raw materials by weight: the traditional Chinese medicine composition for treating chronic atrophic gastritis is prepared by respectively crushing 16g of prepared rehmannia root, 18g of cuttlebone, 11g of adenophora stricta, 14g of radix ophiopogonis, 10g of dogwood, 14g of white paeony root, 11g of codonopsis pilosula, 10g of bighead atractylodes rhizome, 32g of fructus cannabis, 18g of platycladi seed, 16g of spina date seed, 8g of polygonatum odoratum, 8g of honey-fried licorice root, 7g of pseudo-ginseng, 12g of tortoise plastron and 4g of rhizoma anemarrhenae, sieving the crushed materials with a 80-mesh sieve, and uniformly mixing the materials.
The traditional Chinese medicine composition for treating chronic atrophic gastritis is used alone or as an active component in the preparation of medicines for treating chronic atrophic gastritis.
A medicine for treating chronic atrophic gastritis is prepared by adding one or more pharmaceutically acceptable adjuvants into the above Chinese medicinal composition for treating chronic atrophic gastritis, wherein the adjuvants comprise one or more of starch, microcrystalline cellulose, cacao butter, carbomer, sodium benzoate, poloxamer and benzalkonium bromide, and making into tablet by conventional method.
And (3) clinical observation:
1. case selection: the 50 cases, aged 38-68 years, are all patients with chronic atrophic gastritis.
2. Method of treatment
3g of the water-bindered pill of the medicine for treating chronic atrophic gastritis prepared in the example 1 is taken 3 times a day for 3 months to 1 year, and spicy food is avoided during the taking.
3. Clinical symptoms
The included cases meet the diagnosis standard of chronic atrophic gastritis and precancerous lesion in the digestive system of China medical society in 2012, and the traditional Chinese medicine syndrome differentiation standard meets the symptoms of sex-stimulating disorder, stomach dysfunction caused by liver and spleen, gastric mucosa injury, internal stasis of toxin stasis, stomach discomfort, pain or swelling, repeated disunion, or incoordination between the mouth, stool, knot or loose, poor sleep, depression or dysphoria, thin and yellow or thin and clean tongue fur, crackle, purple and dark sublingual vein, and wiry and slippery pulse.
4. Standard of care
And (3) curing: the main clinical symptoms disappear, and the secondary symptoms basically disappear or disappear; the gastroscope rechecks that the active inflammation disappears, and the chronic inflammation is improved to be mild; the biopsy tissue pathology confirms that the gland atrophy, the enterogenesis and the dysplasia are resolved or disappeared as seen by a gastroscope;
the effect is shown: the main clinical symptoms disappear, and the secondary symptoms basically disappear; the gastroscope rechecks that the acute inflammation of the mucous membrane basically disappears and the chronic inflammation is improved; biopsy tissue pathology confirmed gastroscopy that gland atrophy, enterogenesis and dysplasia were significantly reduced;
the method has the following advantages: the main symptoms are obviously relieved; the lesion range of the mucous membrane is reduced by more than 1/2 in gastroscopy, and the inflammation is reduced to some extent; the biopsy tissue pathology proves that acute and chronic inflammation is reduced, gland atrophy, enterogenesis and dysplasia are reduced as seen by a gastroscope;
and (4) invalidation: no improvement in symptoms, scope and pathology.
5. Clinical results
Of 50 patients, 25 patients are cured (50%), 10 patients are obviously effective (20%), 10 patients are effective (20%), 5 patients are ineffective (10%), and the total effective rate is 90%.
6. Typical cases
Case 1: sunzhi, male, age 53, has chronic atrophic gastritis. After 3g of the watered pill of the traditional Chinese medicine composition for treating chronic atrophic gastritis in the embodiment 1 of the invention is taken 3 times a day and is taken for 1 year, the repeated examination results show that the pathological changes are improved through gastroscopy and biopsy. The follow-up visit is carried out after 3 months, subjective symptoms do not relapse, the gland atrophy part is obviously improved compared with the gland atrophy part before treatment, and the atrophy degree is also reduced.
Case 2: a male, age 58, has chronic atrophic gastritis. 3g of the watered pill of the traditional Chinese medicine composition for treating chronic atrophic gastritis in the embodiment 2 of the invention is taken 3 times a day, half a year of taking, and gastroscopy and biopsy prompt show that the pathological changes are improved. The follow-up visit is carried out after 3 months, subjective symptoms do not relapse, gland atrophy parts are obviously improved compared with those before treatment, and the atrophy degree is also reduced.
Case 3: one, male, 62 years old, has chronic atrophic gastritis. 3g of the watered pill of the traditional Chinese medicine composition for treating chronic atrophic gastritis in the embodiment 2 of the invention is taken 3 times a day for 5 months, and the pathological changes are improved by gastroscopy and biopsy prompting. The follow-up visit is carried out after 3 months, subjective symptoms do not relapse, the gland atrophy part is obviously improved compared with the gland atrophy part before treatment, and the atrophy degree is also reduced.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that fall within the spirit and principle of the present invention are intended to be included therein.

Claims (4)

1. The traditional Chinese medicine composition for treating chronic atrophic gastritis is characterized by being prepared from the following raw materials in parts by weight: 14 parts of prepared rehmannia root, 22 parts of cuttlebone, 7 parts of adenophora stricta, 16 parts of dwarf lilyturf tuber, 8 parts of dogwood, 16 parts of white paeony root, 7 parts of codonopsis pilosula, 14 parts of bighead atractylodes rhizome, 28 parts of fructus cannabis, 22 parts of platycladi seed, 14 parts of spina date seed, 10 parts of polygonatum odoratum, 4 parts of honey-fried licorice root, 11 parts of pseudo-ginseng, 8 parts of tortoise plastron and 6 parts of rhizoma anemarrhenae; the preparation method of the traditional Chinese medicine composition for treating chronic atrophic gastritis comprises the following steps:
respectively weighing the following raw materials in parts by weight: 14 parts of prepared rehmannia root, 22 parts of cuttlebone, 7 parts of adenophora stricta, 16 parts of dwarf lilyturf tuber, 8 parts of dogwood, 16 parts of white paeony root, 7 parts of codonopsis pilosula, 14 parts of bighead atractylodes rhizome, 28 parts of fructus cannabis, 22 parts of platycladi seed, 14 parts of spina date seed, 10 parts of polygonatum odoratum, 4 parts of honey-fried licorice root, 11 parts of pseudo-ginseng, 8 parts of tortoise plastron and 6 parts of rhizoma anemarrhenae, which are respectively crushed, sieved and uniformly mixed to obtain the traditional Chinese medicine composition for treating chronic atrophic gastritis.
2. The use of the Chinese medicinal composition for treating chronic atrophic gastritis as defined in claim 1 alone or as an active ingredient in the preparation of a medicament for treating chronic atrophic gastritis.
3. A medicine for treating chronic atrophic gastritis is characterized in that the traditional Chinese medicine composition for treating chronic atrophic gastritis in claim 1 is added with one or more pharmaceutically acceptable auxiliary materials and prepared into water pills, granules, tablets or capsules according to a conventional process.
4. The medicine for treating chronic atrophic gastritis of claim 3, wherein the adjuvant comprises any one or more of starch, microcrystalline cellulose, cocoa butter, carbomer, sodium benzoate, poloxamer and benzalkonium bromide.
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