CN106668409A - Hui traditional Chinese medicine hedyotis diffusa willd anti-esophageal cancer oral liquid and preparation method thereof - Google Patents
Hui traditional Chinese medicine hedyotis diffusa willd anti-esophageal cancer oral liquid and preparation method thereof Download PDFInfo
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Abstract
The invention relates to a formula and a preparation method of a Hui traditional Chinese medicine hedyotis diffusa willd anti-esophageal cancer oral liquid. According to the present invention, the Hui traditional Chinese medicine hedyotis diffusa willd anti-esophageal cancer oral liquid is the green high-tech Chinese herb for esophageal cancer treatment; and hedyotis diffusa willd, scutellaria barbata, panax notoginseng and other Chinese herbs are mixed according to a certain ratio, water is added, and decoction, extraction and concentration are performed to obtain the traditional Chinese medicine oral liquid; and the Hui traditional Chinese medicine hedyotis diffusa willd anti-esophageal cancer oral liquid mainly treats esophageal cancer, can further treat throat cancer, stomach cancer, large intestine cancer and other digestive system cancers, and has characteristics of moderate components and moderate doses, wherein the modern medical pharmacology experiment results prove that the selected medicines can treat cancers, and the body functions are fundamentally improved and the cell cancerization is prevented in the low cost manner so as to recover the health body.
Description
Technical field
The herbvore pipe antitumor oral liquid of Hui ethnic group's Chinese medicine tongue according to the present invention is that a kind of green of the prevention and treatment cancer of the esophagus is high
Scientific and technological Chinese herbal medicine.The invention further relates to the preparation method of the medicine, belongs to traditional Chinese medicine class.
Background technology
According to《China's tumour registration annual report in 2014》Data display, according to China for each person 74 years old life-span calculate, China
The probability that people suffers from malignant tumour in all one's life is 22%, and average minute clock has 6 people to be diagnosed as malignant tumour, tumour China into
For a kind of common disease.At present the cancer patient of China is about ten thousand people more than 700, and every year with the speed of more than 100 ten thousand people in increase.
And the whole world
According to statistics, in the cancer patient of China nearly 8,000,000, have 31.27% for Alimentary System patient, wherein patient with esophageal carcinoma
Account for the 29.7% of Alimentary System patient, almost half.
Cancer of the esophagusDisease locus typically organize in epithelium of esophagus, its directly impact be exactly that patient swallows and digest work(
Can, health is slowly etched with regard to this.The pathogenic factor of cancer of the esophagus mainly has three, and one is malnutritive, though i.e. people now
Living standard improve, but due to the change of diet hobby and mode, will also result in malnutritive and trace element lacking
It is weary;Two is that diet is lack of standardization, and in the grain and drinking-water of district occurred frequently, nitrate, nitrite and secondary amine content significantly increase,
These materials are easily-synthesized carcinogen nitrosamine in stomach;Three be esophageal injury and disease induction, esophageal injury and some food
Pipe disease is likely to become the inducement for causing cancer of the esophagus, is detained and cause long-term chronic inflammation, ulcer because of in oesophagus, or slowly
Sexual stimulus, and then esophageal epithelial proliferation, finally result in canceration.Although cancer of the esophagus does not possess infectiousness, the destruction to human body
But it is not allow to look down upon.
Though the early symptom of the cancer of the esophagus is more substantially, usual to be always mistakenly considered flu etc by people, therefore is often neglected
Depending on, but do not know that the speed that cancer of the esophagus slowly deteriorates is very fast, once and feel increasingly apparent to be difficult to swallow, most likely
Deteriorate as cancer.Afterwards may be by operation to the process of cancerization Regional resection, to reduce the death rate of cancer of the esophagus.
At present treatment cancer of the esophagus the best way is operation, postoperative to be also performed to chemotherapy, and chemotherapy not only large side effects, suffer from
Person's pain is difficult to stand, and success rate is also very low, and the life cycle after most Chemotherapy in Patients was with regard to 1 year or so --- certainly
This is also relevant with the over-treatment given birth to without skilful doctor.And on the other hand, although some perform the operation, due to a variety of causes
Hold and can't stand chemotherapy, can only palliative treatment, expect that miracle comes ...
The cancer of the esophagus is at present more refractory disease more as cancer of the stomach, all, but refractory representative cannot be controlled, except above-mentioned doctor trained in Western medicine
Outside treatment method, the traditional Chinese medical science also has many effectively treatment methods.The traditional Chinese medical science is with organic conception according to the dialectical opinion of whole body feature of patient
Control, go for various each phase cancer.The advantage of Chinese medicine cancer is to be conducive to stablizing the state of an illness, and toxic and side effect is light
Micro-, symptom improves more apparent, slows down PD, tumor regression or the longer-term existence of band knurl, and patient is easy to receive and expense
Than less expensive.At present doctor trained in Western medicine is also considered as traditional Chinese medicine can contribute to reducing the toxicity of Radiotherapy chemotherapy as the auxiliary treatment of cancer,
Improve cancer related symptoms, improve life quality, extend life cycle.But the problem for existing is that the prescription uniformity of the traditional Chinese medical science is poor,
Treatment mainly be experience.From in terms of existing proved recipe for cancer, folk prescription, always have in selected Chinese herbal medicine medicinal material --- it is most
It is more than more than half --- medicine is all not proved function for cancer and acted on by modern medicine pharmacological evaluation " to distinguish
Card treat " " compatibility " medicine, inventors believe that very improper;And folk prescription, folk prescription cure the disease lean on be test, often delay control
The time of disease.
The content of the invention
The purpose of the present invention, be aiming at Cancer in China patient assessment be difficult to and in the side's of curing the desease poor consistency, repeatability
Poor, high level evidence-based medicine EBM is theoretical and evidence is relative lacks, thus the situation for mainly waiting deficiency by rule of thumb for cancer, proposition one
The new dosage of kind and preparation method, there is provided one kind reduces the incidence of disease of the cancer of the esophagus from the beginning of prevention, starts to subtract from canceration
Delay its tempo, the green high-tech Chinese herbal medicine for inducing its atrophy apoptosis is started from tumour.Specifically, the present invention one is special
Shi Yongyu esophageal ulcer before cancer not treated in case its canceration, two is can to treat cancer just ulcer, in case it continues to deteriorate, three
It is inducible into the cancerous swelling atrophy apoptosis of knurl, with very low cost, fundamentally improves physical function, so as to recover strong
Health.Its sharpest edges are to greatest extent to induce self apoptosis of cancer cell and differentiation, promote cancerous swelling progressively atrophy.In tool
In the formula of body, also coordinate diagnosis and treatment based on an overall analysis of the illness and the patient's condition, induced because of esophageal injury, disease according to the origin cause of formation of cancer of the esophagus, dietary preferences nutrition is lost
Weighing apparatus causes immunologic hypofunction, causes normal cell to be compromised because of Helicobacter pylori infection, apoptosis, and digestive tract ulcer, canceration " are taken advantage of
It is empty and enter ", because " weakened body resistance poison is poly- ", " void in healthy tendency " and the characteristics of cause the basic pathology interpretation of the cause, onset and process of an illness such as metastases, with or righting dispel
Heresy, orTonification and purgation in combination, or regulating qi to disperse stagnation, or solve strongly fragrant resolving sputum, or clearing heat and detoxicating, or reinforcing and reducing methods and the method used, with correct void in healthy tendency,
Poly- and internal organs imbalance of yin and yang function reduction the deficiency of the solidifying poison of heresy, adjusts and improves the immunologic function of body, to reach overall tumor suppression
Purpose, so as to improve the overall curative effect and late result of carninomatosis treatment, provides for esophageal cancer patients and a kind of is cured by modern
Learn green high-tech Chinese herbal medicine formula and compound method that pharmacological evaluation proves function for cancer and effect, with very low or
Relatively low cost, fundamentally improves physical function, and the deterioration of symptom management simultaneously makes the state of an illness gradually take a turn for the better, and the final body that recovers is good for
Health.Thus also to patient one according to the personal state of an illness, economic situation, personal inclination come consider select different treatment methods or
Several method shares particularly traditional Chinese and western medicine and combines the leeway of complex treatment application, to obtaining optimum curative effect, easily improves life
Deposit rate --- particularly more than 5 years survival rates.
Technical scheme proposed by the invention is:
First, herbvore pipe antitumor oral liquid of Hui ethnic group's Chinese medicine tongue of the described prevention and treatment cancer of the esophagus and preparation method thereof, is by under
Made by row weight proportion raw material:
Oldenlandia diffusa 30g, Sculellaria barbata 30g, salvia chinensis 10g, pseudo-ginseng 7g,
Seed of Chinese dodder 15g, airpotato yam 7g, rhizoma arisaematis 5g, cultivated land 20g,
Radix Codonopsis 15g, 7 pieces of date, coptis 3g, honey 30g
This side is substantially square for one decoction on the one.In practical application, can also be increased according to the physique of patient and conditions
Plus " dialectical compatibility " medicine that the 1-3 taste traditional Chinese medical science " harmony between man and nature, dialectical treatmert " is theoretical.
In view of with this, basic side's decoction decoction of medicinal ingredients amount is big, taste is not good enough, patient is difficult to drink, therefore must apply special process
It is prepared.
2nd, it is by the preparation method that above-mentioned each raw material makes traditional Chinese medicine oral liquid of the present invention:
The preparation of A, extract
(1), extract
A, for the first time extraction:By the weight of said herbal medicine in addition to the coptis, honey, all amplify 10 times, after clean water, put
Extract in kettle, plus after 7-9 times of running water in BT-2 stainless steels, be heated to 100 DEG C of constant temperature and extract 1 hour or so, separation and Extraction
Liquid, pressure filtration, filtrate is standby.
B, second extraction:Add in kettle the 5-7 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract half an hour
Left and right, extraction fluid, pressure filtration, filtrate is standby.
C, third time are extracted:Add in kettle the 3-5 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract 20 minutes
Left and right, extraction fluid, pressure filtration, filtrate is standby.
(2), concentration
The extract of three times is merged, is placed in B-500 type triple effect vacuum high energy evaporation concentrators, reduced pressure (negative 200mmHg),
80 DEG C are heated to, 900ml is concentrated into, it is standby.
(3), powder processed
Coptis 3g is amplified into 10 times, is crushed as end, cross 100 mesh sieves, it is standby in being fitted into every 0.5g capsule.
(4), dispensing
In 300,000 grades of dust proof workshops, aforementioned concentrate is put in mixer together with 30g honey and is sufficiently mixed, stir.
B, packaging
A. in the concentrate for preparing being fitted into into vial or vinyon bottle, every bottle of 30ml, mounted box, vanning, sterilizing (are adopted
60Co irradiation is used, irradiation dose is 8kGy).
B. in capsule being fitted into into vial or vinyon bottle, mounted box, vanning, sterilizing (adopt 60Co irradiation, irradiation agent
Measure as 8kGy).
C, warehouse-in
Irradiated finished product is put in storage by the principle of first in first out.
Routine instructions of taking of the invention:Three times a day, every time 1 bottle, on an empty stomach (taking half an hour after can not drink water in a large number, in order to avoid water down
Liquid).2 coptis capsules are taken while each taking decoction.During medication eat pungent grade to gastrointestinal irritation compared with
Big food.
The effect of each raw material of the present invention:
Long-noded pit viper house grass:Effect:It is clearing heat and detoxicating, diuresis of blood circulation promoting, Xiaofeng San gas, removing toxic substances detumescence, pain relieving.Cure mainly:Lung heat, intestines heat,
Heat accumulating in the large intestine, laryngalgia, sore swells, snake sore, all enterodynia, appendicitis, tonsillitis, sphagitis, urinary tract infections, pelvic infecton, appendix
Inflammation, hepatitis, bacillary dysentery, venomous snake bite, tumour.Also can be used for alimentary tract cancer.Modern pharmacology research proves, Hedyotidis Diffusae energy
Strengthen the immunity of body, suppress the growth of tumour cell, to Pseudomonas aeruginosa, staphylococcus aureus, pneumococcus, dysentery bar
The pathogenic bacteria such as bacterium have inhibitory action, are in fact the good medicine of " clearing heat and detoxicating ".
Sculellaria barbata, effect is clearing heat and detoxicating, dissipate stasis of blood hemostasis with effect, and inducing diuresis to remove edema is controlled heat toxin carbuncle swells, had sore throat, lung
Carbuncle, acute appendicitis, venomous snake bite, traumatic injury;Spit blood;Bleeding from five sense organs or subcutaneous tissue;Blood strangury;It is swollen;Ascites and cancer.Effect has with effect and eating method
Sculellaria barbata Radix Astragali eliminating mass ball, four aurification stasis of blood Paishi Tangs, Sculellaria barbata qi-restoratives dampness-eliminating soup.
Salvia chinensis, is the herb of Labiatae annual herb plant salvia chinensis, flavor efficacy:It is bitter, mild-natured.It is clearing heat and detoxicating,
Cool blood flat liver, inducing diuresis for removing edema, dissipating bind.Clinical practice:It is usually used in treating the cancer of the esophagus, carcinoma of parotid gland, liver cancer, cancer of the stomach, cardia cancer etc..Doctor
Learn religion ' educate net compile additionally, be additionally operable to treat virus hepatitis, hot summer weather rush down dysentery, infantile acute nephritis, oedema, rheumatic
Arthritis, chyluria, treating swelling and pain by traumatic injury, venomous snake bite, boil swell and ache, metrorrhagia etc..
Pseudo-ginseng, pseudo-ginseng is one of ten big Chinese herbal medicine for preventing, meridian distribution of property and flavor:Sweet, slight bitter, tepor, Return liver, stomach.Indication
Removing blood stasis and hemostasis, activating blood circulation and reducing swelling analgesic therapy.It is clinicalOn applying clinical commonly use control lung cancer, the cancer of the esophagus,Cervical carcinomaBelong to stagnation of blood stasis etc. carcinoma
Or and bleeder.Cure mainly it is various go out blood trouble, fall servant's stasis of blood swell, chest impediment and cardialgia.Arasaponin Rd can make the tumour cell 92% of culture
It is suppressed, Rd also has obvious inhibiting effect to the oncocyte cultivated.Saponin Rhl can suppress murine melanoma(B16)Life
Long, again induction is reversed into non-cancerous cells to make cancer cell.Pseudo-ginseng decoction has inhibitory action to JYC26 in vivo;In pseudo-ginseng
Polysaccharide body can substantially suppress in vivo murine sarcoma -180;Pseudo-ginseng also has antiphagin activity.
The seed of Chinese dodder, it is warm in nature;It is sweet;Return liver, spleen, kidney channel.Effect and nourishing liver and kidney, antiabortive, the improving eyesight of effect, antidiarrheal.For:
Impotence and seminal emission, dripping urination, enuresis frequent micturition, medicine knees soreness, blurred vision tinnitus, vaginal bleeding due to deficiency of the kidney during pregnancy, fetal irritability, spleen kidney deficiency is rushed down;Control outward
Leucoderma, the ability with certain inhibition cancer cell can reduce the incidence of canceration.
Airpotato yam, nature and flavorEffect:Bitter, it is mild-natured, it is slightly poisonous.Removing toxicity for detumescence, reducing phlegm and resolving masses, cooling blood and hemostasis.It is clinicalShould
With:Suitable for kinds of tumors, such as the cancer of the esophagus,Cancer of the stomach, nasopharyngeal carcinoma, thyroid tumors, lymphosarcoma, lung cancer, sonCervical carcinoma, band
Muscle tumor, intestinal cancer and cancer of pancreas etc..Additionally, apply also for endemicgoiter big, hyperthyroidism, tracheitis, hundred
Day cough, hemoptysis, haematemesis, scrofula, sore tumour, venomous snake bite etc..
Rhizoma arisaematis, nature and flavorEffect:It is bitter, pungent, it is warm in nature, it is poisonous.It is eliminating dampness and eliminating phlegm, eliminating the phlegm arresting convulsion, dispersing swelling and dissipating binds.It is clinicalShould
With:Suitable for kinds of tumors, such as tumor in digestive tract, intracranial tumour, brain metastasis, or tumor lympha is carried down shifting, sonUterine neck Cancer、Oral cavityTumour,NerveSystem tumor.Additionally it is applied to heap soil or fertilizer over and around the roots of apoplexy phlegm, facial paralysis, hemiplegia, insane chronic, infantile convulsion, broken
Cold, anemophlegmatic vertigo, larynx numbness, scrofula tuberculosis, carbuncle swells, traumatic injury, snake bite and insect sting etc..
Cultivated land, also known as prepared rhizome of rehmannia.It is sweet, tepor.Return liver and kidney channel.Enter blood system, the soft and moist drop of matter.《This Jing meets original》:" prepared rhizome of rehmannia,
False firepower steaming is shone, and it is sweet to turn hardship, is the yang aspect of yin, therefore vigour in energy kidney tonifying." modern study proves, the glutinous rehmannia contained by prepared rhizome of rehmannia
Polysaccharide has a significantly immunity antitumor activity, also significant cardiac stimulant, diuresis, liver protection,It is hypoglycemic, anti-proliferate, it is impervious go out, resist
Scorching, antimycotic, anti-radiation etc. are acted on.Enrich blood enriching yin, beneficial essence fills out marrow.Cure mainly the deficiency of liver-yin and kidney-yin, soreness and weakness of waist and knees, osteopyrexia and fever, night sweat
Seminal emission, Heat Diabetes, blood deficiency chlorosis, palpitation and severe palpitation, irregular menstruation, metrostaxis, dizzinessTinnitus, poliosis.
Radix Codonopsis, sweet mild-natured, effect relaxes, and is the product of flat benefit, widely applicable, few side effects, therefore ancients often with replacement ginseng
Treat some deficiency of vital energy mild and chronic disease person.The effect of Radix Codonopsis has " bowl spares, beneficial gas are promoted the production of body fluid, invigorating the spleen, beneficial lung, relieving thirst and restlessness ",
Can be used for the diseases such as spleen and lung weakness, shortness of breath palpitations, anorexia and loose stool, virtual asthma cough, Heat Diabetes.Radix Codonopsis also contains reducing blood lipid, blood pressure,
The stifled material of the blood that disappears, so as to the prevention effect that all has some improvement to coronary heart disease and cardiovascular patient.There are regulation heart and brain
Vascular system function, promotes the effect of cardio-cerebrovascular health;Particularly there is hematopoiesis, adjust blood pressure, reduce blood pressure, promote
Blood in human body in liquid is circulated, while also hematopoiesis regeneration, promotes the effect of red blood cell growth.So as to effectively help people to strengthen body
Immunity, improves fitness.Radix Codonopsis is not only able to tonifying Qi, and can also balance digestive system.Drinking soup that Radix Codonopsis boils can be with
Promote gastrointestinal disturbances, and the secretion of gastric juice.So as to allow people to be not only able to have a very good appetite, and can also the intestines such as preventing gastric ulcer
The generation of gastric disease, the immunocompetence for making human body rises, and reduces the incidence of human body diseases.Additionally, according to scientific investigations showed that, taking
After with Radix Codonopsis, can help improve learning ability, and have pneumostatic of calming the nerves, improve the health care of sleep the effect of quality.
Date, also known as red date, dry jujube, Chinese date etc., there is the title of the king of all kinds of fruits.There are tonifying middle-Jiao and Qi, nourishing blood and tranquilization, strengthening the spleen and stomach
Effect.For spleen eating less, weak loose stool, hysteria of womam.It is the patient such as weakness of the spleen and the stomach, insufficiency of vital energy and blood, lassitude, insomnia
Good health nutrient.Date rich in protein, fat, carbohydrate, carrotene, B family vitamins, vitamin C, citrin with
And the composition such as phosphorus, calcium, iron, wherein ascorbic content comes out at the top in fruit, the laudatory title for having vitamin C.Date can be improved
Body immunity, and can inhibition cancer cell.Pharmacological research finds that red date can promote the generation of leucocyte, reduce serum cholesterol,
Seralbumin is improved, liver is protected.Date red date is rich in protein, fat, carbohydrate, carrotene, B family vitamins, vitamin
The nutrient content such as C, citrin and calcium, phosphorus, iron and CAMP.Really(Date):Tonifying middle-Jiao and Qi, nourishing blood and tranquilization.For spleen
Empty deficiency of food, weak loose stool, hysteria of womam.Bark:Anti-inflammatory, hemostasis, antidiarrheal.For tracheitis, enteritis, dysentery, uterine bleeding;External application is controlled
Traumatism and bleeding.Root:Promoting the circulation of qi, promoting blood circulation, menstruation regulating.It is red to collapse for irregular menstruation, leukorrhea.Date is to acute, chronic hepatitis, cirrhosis, lean
The diseases such as blood, anaphylactoid purpura have good therapeutic effect.Date contains triterpene compound and CAMP, has stronger suppression cancer, resists
Allergy is acted on.The CAMP that date is rich in, is the required material of human energy metabolism, can strengthen muscular strength, dispelling fatigue, expansion
Blood vessel is opened, increased myocardial contractive power, improved myocardial nutrition, prevention and cure of cardiovascular disease is played the role of good.Date has qi-restoratives
The effects such as beneficial gas, nourishing blood and tranquilization, strengthening the spleen and stomach, be the good guarantor of the patient such as weakness of the spleen and the stomach, insufficiency of vital energy and blood, lassitude, insomnia
Strong nutriment.The coptis, nature and flavorEffect:It is bitter, cold in nature.Heat-clearing and damp-drying drug, purging intense heat and detonicating.It is clinicalUsing:Suitable for various arsine knurls,
Such as liver, courage tumour, tongue cancer, lip cancer, the cancer of the esophagus,Cancer of the stomach, carcinoma of urinary bladder etc..Additionally, applying also for unconsciousness due to high fever, haematemesis, bleeding from five sense organs or subcutaneous tissue, malignant boil
Pyogenic infections from tumour or sore, wet sore itch, acute conjunctivitis, aphtha, bacillary dysentery, acute bowel helmet inflammation, heat are contained vexed, feeling of fullness, quench one's thirst, burn
Deng disease.
Honey, effect and the effect of honey:1. the good merchantable brand of cardiovascular patient,HoneyThe composition of blood can be improved, promote the heart
Brain and vascular function, therefore Jing informal dresses are very good for cardiovascular patient;2. protect liver, honey to have protection to make to liver
With, liver cell regeneration can be promoted, the formation to fatty liver has certain inhibitory action;3. build up resistance, eating honey can be fast
Speed regains one's strength of body, dispelling fatigue, builds up one's resistance to disease;4. sterilized, honey also has sterilized effect, Jing often to eat honey
Sugar, not only without prejudice to tooth, moreover it is possible to play a part of sterilizing in oral cavity, honey can treat the skin damage of moderate,
Particularly scald, when honey is regarded into skin wound dressing, bacterium cannot grow;5. promote sleep, the people of insomnia to sleep daily
Oral 1 soupspoon honey (adding in 1 glass of warm water), can help fall asleep as early as possible before feeling;6. gastrointestinal peristalsis, honey pair are promoted
Gastrointestinal function has adjustment effect, and gastric acid secretion can be made normal.Zoopery confirms that honey plays the role of to strengthen enterocinesia, can show
Write and shorten defecation time.
The effect of the present invention:
Cure mainly:The cancer of the esophagus, particularly the early stage cancer of the esophagus, with very low cost, fundamentally improve physical function, control tumour after
Continuous overgrowing simultaneously makes it that final disappearance is gradually reduced, so as to recover healthy.
It is simultaneous to control:The cancer in digestive system such as throat cancer, cardiac cancer, pylorus cancer, cancer of the stomach, colorectal cancer.
Our the characteristics of is:
1st, flavour of a drug are more, and dosage is moderate, do not waste.
2nd, selected flavour of a drug are all to be proved that for cancer the cancer of the esophagus particularly can be treated by modern medicine pharmacological evaluation
's.And then always have in existing proved recipe for cancer, folk prescription --- even more than medicine more than half be all not by
Modern medicine pharmacological evaluation proves function for cancer with effect.
3rd, for focus, arrow arrow punching, i.e., selected flavour of a drug all especially grow tender of and hit the bull's eye, and As the medicine took effect, the symptoms lessened.Rather than only
It is for cancer, just jump on the bandwagon, as a result it is that " dragon " does not harness the river on the contrary more.
4th, as much as possible " neutralisation ", i.e., selected flavour of a drug generally keep " neutrality ", do not tremble with fear not dry, not hot not cool.This
Sample can just make patient suffer less within the cycle of whole medication, pull the devil by the tail less.And if really occurring " getting angry " or " under let out "
Situation, then can be directed to concrete individual concrete condition completely, a bit " stopping leak ", the medicine of " fall fire " are specifically solved for interim addition
Certainly.Rather than imagine at the very start patient may on tell or drop, and some unnecessary medicine sides of being added to
Son, makes patient all take always during very long very long medication, ultimately causes adverse consequences.
Specific embodiment:By oldenlandia diffusa 30g, Sculellaria barbata 30g, salvia chinensis 10g, pseudo-ginseng 7g, seed of Chinese dodder 15g, party
Ginseng 15g, airpotato yam 7g, rhizoma arisaematis 5g, cultivated land 20g, 7 pieces of date respectively amplify 10 times, after clean water, are placed in BT-2 stainless steels
In extracting kettle, plus after 7-9 times of running water, it is heated to 100 DEG C of constant temperature and extracts 1 hour or so, extraction fluid, pressure filtration, filter
Liquid is standby.Extract for second:Add in kettle the 5-7 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature extraction half an hour left
The right side, extraction fluid, pressure filtration, filtrate is standby.Third time is extracted:Add in kettle the 3-5 times of running water measured toward extracting, heating
Extract 20 minutes or so to 100 DEG C of constant temperature, extraction fluid, pressure filtration, filtrate is standby.Concentration:The extract of three times is closed
And, it is placed in B-500 type triple effect vacuum high energy evaporation concentrators, reduce pressure (negative 200mmHg), it is heated to 80 DEG C, is concentrated into
900ml, it is standby.Powder processed:Coptis 3g is respectively amplified 10 times, is crushed as end, cross 100 mesh sieves, it is standby in being fitted into every 0.5g capsule
With.Dispensing:In 300,000 grades of dust proof workshops, aforementioned concentrate is put in mixer together with 30g honey and is sufficiently mixed, stirring is equal
It is even.Packaging:A. in the concentrate for preparing being fitted into into vial or vinyon bottle, every bottle of 30ml, mounted box, vanning, sterilizing
(60Co irradiation is adopted, irradiation dose is 8kGy).B. in capsule being fitted into into vial or vinyon bottle, mounted box, vanning,
Sterilizing (adopts 60Co irradiation, irradiation dose is 8kGy).Finally, irradiated finished product is entered by the principle of first in first out
Storehouse.
Claims (2)
1. herbvore pipe antitumor oral liquid of Hui ethnic group's Chinese medicine tongue and preparation method thereof, it is characterised in that it is by the original of following weight proportion
Made by material:
Oldenlandia diffusa 30g, Sculellaria barbata 30g, salvia chinensis 10g, pseudo-ginseng 7g,
Seed of Chinese dodder 15g, airpotato yam 7g, rhizoma arisaematis 5g, cultivated land 20g,
Radix Codonopsis 15g, 7 pieces of date, coptis 3g, honey 30g
This side is the substantially square of one decoction on the one, in practical application, can also be increased according to the physique of patient and conditions
Theoretical " dialectical compatibility " medicine of the 1-3 taste traditional Chinese medical science " harmony between man and nature, dialectical treatmert ".
2. the weight proportion of the herbvore pipe antitumor oral liquid of Hui ethnic group's Chinese medicine tongue according to claim 1, it is characterised in that include
Following preparation processes:
The preparation of A, extract
(1), extract
A, for the first time extraction:By the weight of said herbal medicine in addition to the coptis, honey, all amplify 10 times, after clean water, put
Extract in kettle, plus after 7-9 times of running water in BT-2 stainless steels, be heated to 100 DEG C of constant temperature and extract 1 hour or so, separation and Extraction
Liquid, pressure filtration, filtrate is standby;
B, second extraction:Add in kettle the 5-7 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract or so half an hour,
Extraction fluid, pressure filtration, filtrate is standby;
C, third time are extracted:Add in kettle the 3-5 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract 20 minutes or so,
Extraction fluid, pressure filtration, filtrate is standby;
(2), concentration
The extract of three times is merged, is placed in B-500 type triple effect vacuum high energy evaporation concentrators, reduced pressure (negative 200mmHg), plus
Heat is concentrated into 900ml to 80 DEG C, standby;
(3), powder processed
Coptis 3g is amplified into 10 times, is crushed as end, cross 100 mesh sieves, it is standby in being fitted into every 0.5g capsule;
(4), dispensing
In 300,000 grades of dust proof workshops, aforementioned concentrate is put in mixer together with 30g honey and is sufficiently mixed, stir;
B, packaging
A. in the concentrate for preparing being fitted into into vial or vinyon bottle, every bottle of 30ml, mounted box, vanning, sterilizing (are adopted
60Co irradiation is used, irradiation dose is 8kGy);
B. in capsule being fitted into into vial or vinyon bottle, (using 60Co irradiation, irradiation dose is for mounted box, vanning, sterilizing
8kGy);
C, warehouse-in
Irradiated finished product is put in storage by the principle of first in first out.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510749294.2A CN106668409A (en) | 2015-11-08 | 2015-11-08 | Hui traditional Chinese medicine hedyotis diffusa willd anti-esophageal cancer oral liquid and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510749294.2A CN106668409A (en) | 2015-11-08 | 2015-11-08 | Hui traditional Chinese medicine hedyotis diffusa willd anti-esophageal cancer oral liquid and preparation method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108465066A (en) * | 2018-04-13 | 2018-08-31 | 邰殿忠 | The composition for the treatment of cancer |
| CN109419956A (en) * | 2017-08-22 | 2019-03-05 | 曾令元 | A kind of Chinese medicine composition that treating cancer of the esophagus and preparation method |
-
2015
- 2015-11-08 CN CN201510749294.2A patent/CN106668409A/en not_active Withdrawn
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109419956A (en) * | 2017-08-22 | 2019-03-05 | 曾令元 | A kind of Chinese medicine composition that treating cancer of the esophagus and preparation method |
| CN108465066A (en) * | 2018-04-13 | 2018-08-31 | 邰殿忠 | The composition for the treatment of cancer |
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