CN106668421A - Hui-nationality traditional Chinese medicine granule with herba hedyotidis diffusae for resisting esophagus cancer and preparation method thereof - Google Patents

Hui-nationality traditional Chinese medicine granule with herba hedyotidis diffusae for resisting esophagus cancer and preparation method thereof Download PDF

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CN106668421A
CN106668421A CN201510750654.0A CN201510750654A CN106668421A CN 106668421 A CN106668421 A CN 106668421A CN 201510750654 A CN201510750654 A CN 201510750654A CN 106668421 A CN106668421 A CN 106668421A
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cancer
traditional chinese
medicine
chinese medicine
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王学礼
赵宁
马芳
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Yinchuan Shanghetu New Technology Development Co Ltd
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Yinchuan Shanghetu New Technology Development Co Ltd
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Abstract

The invention specifically discloses a formula of a Hui-nationality traditional Chinese medicine granule with herba hedyotidis diffusae for resisting esophagus cancer and a preparation method thereof. The medicine is a green and high-tech traditional Chinese herbal medicine for treating esophagus cancer. The medicine is a traditional Chinese medicine granule prepared by mixing traditional Chinese herbal medicines such as herba hedyotidis diffusae, herba scutellariae barbatae and radix notoginseng and the like according to a certain ratio, adding water for decocting, extracting, concentrating and granulating. The traditional Chinese medicine granule is mainly used for treating esophagus cancer and is also used for treating digestive system cancers such as pharyngolaryngeal cancer, gastric cancer and colorectal cancer and the like. The traditional Chinese medicine granule has the characteristics of moderate medicine and dosage; the modern medical pharmacology experiments show that the selected traditional Chinese medicines can be used for treating cancers; the traditional Chinese medicine granule is low in cost and is capable of fundamentally improving physical functions as well as preventing and treating cell canceration so as to restore physical health.

Description

Herbvore pipe Kangai Granula of Hui ethnic group's Chinese medicine tongue and preparation method thereof
Technical field
The herbvore pipe Kangai Granula of Hui ethnic group's Chinese medicine tongue according to the present invention is a kind of green high-tech Chinese herbal medicine of the prevention and treatment cancer of the esophagus.The invention further relates to the preparation method of the medicine, belongs to traditional Chinese medicine class.
Background technology
According to《China's tumour registration annual report in 2014》Data display, according to China for each person 74 years old life-span calculate, Chinese all one's life suffer from malignant tumour probability be 22%, average minute clock has 6 people to be diagnosed as malignant tumour, and tumour has become a kind of common disease in China.At present the cancer patient of China is about ten thousand people more than 700, and every year with the speed of more than 100 ten thousand people in increase.And the whole world
According to statistics, in the cancer patient of China nearly 8,000,000, have 31.27% for Alimentary System patient, wherein patient with esophageal carcinoma accounts for the 29.7% of Alimentary System patient, almost half.
Cancer of the esophagusDisease locus are typically organized in epithelium of esophagus, and it is exactly swallowing and digestive function for patient that it directly affects, and health is slowly etched with regard to this.The pathogenic factor of cancer of the esophagus mainly has three, and one is malnutritive, though that is, now the living standard of people improves, due to the change of diet hobby and mode, will also result in malnutritive and trace element shortage;Two is that diet is lack of standardization, and in the grain and drinking-water of district occurred frequently, nitrate, nitrite and secondary amine content significantly increase, and these materials are easily-synthesized carcinogen nitrosamine in stomach;Three is esophageal injury and disease induction, and esophageal injury and some esophagel diseases are likely to become the inducement for causing cancer of the esophagus, and long-term chronic inflammation, ulcer, or chronic stimulation, and then esophageal epithelial proliferation are caused because of being detained in oesophagus, finally result in canceration.Although cancer of the esophagus does not possess infectiousness, the destruction to human body is but not allow to look down upon.
Though the early symptom of the cancer of the esophagus is more substantially, generally always flu etc is mistakenly considered by people, therefore often ignored, but do not know that the speed that cancer of the esophagus slowly deteriorates is very fast, once and feel increasingly apparent to be difficult to swallow, most likely deteriorated as cancer.Afterwards may be by operation to the process of cancerization Regional resection, to reduce the death rate of cancer of the esophagus.
At present treatment cancer of the esophagus the best way is operation, postoperative to be also performed to chemotherapy, and chemotherapy not only large side effects, patient suffering is difficult to stand, and success rate is also very low, the life cycle after most Chemotherapy in Patients was with regard to 1 year or so --- certainly this is also relevant with the over-treatment given birth to without skilful doctor.And on the other hand, although some perform the operation, held due to a variety of causes and can't stand chemotherapy,Can only palliative treatment, expect that miracle comes ...
The cancer of the esophagus is at present more refractory disease more as cancer of the stomach, all, but refractory representative cannot be controlled, and in addition to above-mentioned western medical treatment method, the traditional Chinese medical science also has many effectively treatment methods.The traditional Chinese medical science, according to the whole body feature diagnosis and treatment of patient, goes for various each phase cancer with organic conception.The advantage of Chinese medicine cancer is to be conducive to stablizing the state of an illness, and toxic and side effect is slight, symptom improves more apparent, slows down PD, tumor regression or the longer-term existence of band knurl, and patient is easy to receive and expense is than less expensive.At present doctor trained in Western medicine is also considered as traditional Chinese medicine can contribute to reducing the toxicity of Radiotherapy chemotherapy as the auxiliary treatment of cancer, improve cancer related symptoms, improve life quality, extend life cycle.But exist problem be the traditional Chinese medical science prescription uniformity it is poor, treatment mainly be experience.From in terms of existing proved recipe for cancer, folk prescription, always there is --- majority is more than more than half --- medicine to be all not prove " compatibility " medicine of function for cancer and effect " diagnosis and treatment based on an overall analysis of the illness and the patient's condition " by modern medicine pharmacological evaluation in selected Chinese herbal medicine medicinal material, inventors believe that very improper;And folk prescription, folk prescription cure the disease lean on be test, often stop over the time cured the disease.
The content of the invention
The purpose of the present invention, be aiming at Cancer in China patient assessment be difficult to and in the side's of curing the desease poor consistency, repeatable poor, high level evidence-based medicine EBM be theoretical and the relative shortage of evidence,Thus the situation for waiting deficiency by rule of thumb that is mainly for cancer, propose a kind of new dosage and preparation method, there is provided one kind reduces the incidence of disease of the cancer of the esophagus from the beginning of prevention, start to slow down its tempo from canceration, the green high-tech Chinese herbal medicine for inducing its atrophy apoptosis is started from tumour.Specifically, the present invention one is particularly suited for use in esophageal ulcer before treatment cancer in case its canceration, two is can to treat cancer just ulcer, in case it continues to deteriorate, three is inducible into the cancerous swelling atrophy apoptosis of knurl, with very low cost, fundamentally improve physical function, so as to get well.Its sharpest edges are to greatest extent to induce self apoptosis of cancer cell and differentiation, promote cancerous swelling progressively atrophy.In specific formula, also coordinate diagnosis and treatment based on an overall analysis of the illness and the patient's condition, induced because of esophageal injury, disease according to the origin cause of formation of cancer of the esophagus, dietary preferences nutrient imbalance causes immunologic hypofunction, cause normal cell to be compromised because of Helicobacter pylori infection, apoptosis, digestive tract ulcer, canceration " taking advantage of a weak point ", because " weakened body resistance poison poly- ", " empty in healthy tendency " and the characteristics of causes the basic pathology interpretation of the cause, onset and process of an illness such as metastases, utilization or strengthening vital QI to eliminate pathogenic factors, orTonification and purgation in combination, or regulating qi to disperse stagnation, or the strongly fragrant resolving sputum of solution, or it is clearing heat and detoxicating, or reinforcing and reducing methods and the method used, it is empty in healthy tendency to correct, poly- and internal organs imbalance of yin and yang function reduction the deficiency of the solidifying poison of heresy, adjust and improve the immunologic function of body, to reach the purpose of overall tumor suppression, so as to improve the overall curative effect and late result of carninomatosis treatment, a kind of green high-tech Chinese herbal medicine formula and compound method that function for cancer and effect are proved by modern medicine pharmacological evaluation is provided for esophageal cancer patients, with very low or relatively low cost, fundamentally improve physical function, the deterioration of symptom management simultaneously makes the state of an illness gradually take a turn for the better, finally recover healthy.Thus also to patient one select different treatment methods or several method to share particularly traditional Chinese and western medicine to combine the leeway of complex treatment application to consider according to the personal state of an illness, economic situation, personal inclination, to obtaining optimum curative effect, survival rate is easily improved --- particularly more than 5 years survival rates.
Technical scheme proposed by the invention is:
First, herbvore pipe Kangai Granula of Hui ethnic group's Chinese medicine tongue of the described prevention and treatment cancer of the esophagus and preparation method thereof, is by made by following weight proportion raw material:
Oldenlandia diffusa 30g, Sculellaria barbata 30g, salvia chinensis 10g, pseudo-ginseng 7g,
Seed of Chinese dodder 15g, airpotato yam 7g, rhizoma arisaematis 5g, cultivated land 20g,
Radix Codonopsis 15g, 7 pieces of date, coptis 3g, honey 30g
This side is substantially square for one decoction on the one.In practical application, also the 1-3 taste traditional Chinese medical science " harmony between man and nature, dialectical treatmert " theory can be increased according to the physique of patient and conditionsDialectical compatibility " medicine.
In view of with this, basic side's decoction decoction of medicinal ingredients amount is big, taste is not good enough, patient is difficult to drink, therefore must be prepared using special process.
2nd, it is by the preparation method that above-mentioned each raw material makes Chinese medicinal granule of the present invention:
A, extract preparation
(1), extract
A, for the first time extraction:By the weight of said herbal medicine in addition to Radix Codonopsis, the coptis, honey, all amplify 10 times, after clean water, it is placed in BT-2 stainless steels to extract in kettle, plus after 7-9 times of running water, is heated to 100 DEG C of constant temperature and extracts 1 hour or so, extraction fluid, pressure filtration, filtrate is standby.
B, second extraction:Add in kettle the 5-7 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract or so half an hour, extraction fluid, pressure filtration, filtrate is standby.
C, third time are extracted:Add in kettle the 3-5 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract 20 minutes or so, extraction fluid, pressure filtration, filtrate is standby.
(2), concentration
The extract of three times is merged, is placed in B-500 type triple effect vacuum high energy evaporation concentrators, reduced pressure (negative 200mmHg), be heated to 80 DEG C, be concentrated into relative density 1.10~1.20, it is standby.
(3), powder processed
Radix Codonopsis 15g, coptis 3g are amplified into 10 times, it is end together to crush, cross 100 mesh sieves, it is standby.
(4), dispensing
In 300,000 grades of dust proof workshops, above-mentioned medicinal powder is put in mixer together with aforementioned concentrate and 30g honey and is sufficiently mixed, stir.
(5) drying, crushing
The spice being well mixed is placed in into 60-70 DEG C of baking 4-5 hour in baking oven, is then crushed, cross 100 mesh sieves.
(6) granulate
The spice being well mixed is inserted in comminutor and is granulated.
(7) whole grain
The particle for making is carried out into whole grain, 35 mesh sieves are crossed.
(8) it is dried
Whole good particle is inserted in heat circulation drying oven, aeration-drying is to moisture < 8% at 80 DEG C.
B, packaging
First the particle for making is fitted into vinyon pouch, every bag of 8-10g, then the pouch mounted box for installing, vanning, sterilizing (are adopted into 60Co irradiation, irradiation dose is 8kGy).
C, warehouse-in
Irradiated finished product is put in storage by the principle of first in first out.
Routine instructions of taking of the invention:Three times a day, 1 bag of 8-10g every time, on an empty stomach (taking half an hour after can not drink water in a large number, in order to avoid water down liquid).The pungent grade food larger to gastrointestinal irritation is not eaten during medication.
The effect of each raw material of the present invention:
Long-noded pit viper house grass:Effect:It is clearing heat and detoxicating, diuresis of blood circulation promoting, Xiaofeng San gas, removing toxic substances detumescence, pain relieving.Cure mainly:Lung heat, intestines heat, heat accumulating in the large intestine, laryngalgia, sore swells, snake sore, all enterodynia, appendicitis, tonsillitis, sphagitis, urinary tract infections, pelvic infecton, appendicitis, hepatitis, bacillary dysentery, venomous snake bite, tumour.Also can be used for alimentary tract cancer.Modern pharmacology research proves that Hedyotidis Diffusae can strengthen the immunity of body, suppresses the growth of tumour cell, has inhibitory action to pathogenic bacteria such as Pseudomonas aeruginosa, staphylococcus aureus, pneumococcus, shigella dysenteriaes, is in fact the good medicine of " clearing heat and detoxicating ".
Sculellaria barbata,Effect is clearing heat and detoxicating, dissipate stasis of blood hemostasis with effect, and inducing diuresis to remove edema is controlled heat toxin carbuncle swells, had sore throat, lung carbuncle, acute appendicitis, venomous snake bite, traumatic injury;Spit blood;Bleeding from five sense organs or subcutaneous tissue;Blood strangury;It is swollen;Ascites and cancer.Effect has Sculellaria barbata Radix Astragali eliminating mass ball, four aurification stasis of blood Paishi Tangs, Sculellaria barbata qi-restoratives dampness-eliminating soup with effect and eating method.
Salvia chinensis,For the herb of Labiatae annual herb plant salvia chinensis, flavor efficacy:It is bitter, mild-natured.It is clearing heat and detoxicating, cool blood flat liver, inducing diuresis for removing edema, dissipating bind.Clinical practice:It is usually used in treating the cancer of the esophagus, carcinoma of parotid gland, liver cancer, cancer of the stomach, cardia cancer etc..Medical science religion ' educate net compile additionally, be additionally operable to treat virus hepatitis, hot summer weather rush down dysentery, infantile acute nephritis, oedema, rheumatic arthritis, chyluria, treating swelling and pain by traumatic injury, venomous snake bite, boil swell and ache, metrorrhagia etc..
Pseudo-ginseng,Pseudo-ginseng is one of ten big Chinese herbal medicine for preventing, meridian distribution of property and flavor:Sweet, slight bitter, tepor, Return liver, stomach.Indication removing blood stasis and hemostasis, activating blood circulation and reducing swelling analgesic therapy.It is clinicalOn applying clinical commonly use control lung cancer, the cancer of the esophagus,Cervical carcinomaBelong to stagnation of blood stasis or and bleeder etc. carcinoma.Cure mainly it is various go out blood trouble, fall servant's stasis of blood swell, chest impediment and cardialgia.Arasaponin Rd is suppressed can the tumour cell 92% of culture, and Rd also has obvious inhibiting effect to the oncocyte cultivated.Saponin Rhl can suppress murine melanoma(B16)Growth, again induction is reversed into non-cancerous cells to make cancer cell.Pseudo-ginseng decoction has inhibitory action to JYC26 in vivo;Polysaccharide body in pseudo-ginseng can substantially suppress in vivo murine sarcoma -180;Pseudo-ginseng also has antiphagin activity.
The seed of Chinese dodder,It is warm in nature;It is sweet;Return liver, spleen, kidney channel.Effect and nourishing liver and kidney, antiabortive, the improving eyesight of effect, antidiarrheal.For:Impotence and seminal emission, dripping urination, enuresis frequent micturition, medicine knees soreness, blurred vision tinnitus, vaginal bleeding due to deficiency of the kidney during pregnancy, fetal irritability, spleen kidney deficiency is rushed down;Externally treating leucoderma, the ability with certain inhibition cancer cell can reduce the incidence of canceration.
Airpotato yam,Nature and flavorEffect:Bitter, it is mild-natured, it is slightly poisonous.Removing toxicity for detumescence, reducing phlegm and resolving masses, cooling blood and hemostasis.It is clinicalUsing:Suitable for kinds of tumors, such as the cancer of the esophagus,Cancer of the stomach, nasopharyngeal carcinoma, thyroid tumors, lymphosarcoma, lung cancer, sonCervical carcinoma, rhabdomyosarcoma, intestinal cancer and cancer of pancreas etc..Additionally, applying also for big endemicgoiter, hyperthyroidism, tracheitis, pertussis, hemoptysis, haematemesis, scrofula, sore tumour, venomous snake bite etc..
Rhizoma arisaematis,Nature and flavorEffect:It is bitter, pungent, it is warm in nature, it is poisonous.It is eliminating dampness and eliminating phlegm, eliminating the phlegm arresting convulsion, dispersing swelling and dissipating binds.It is clinicalUsing:Suitable for kinds of tumors, such as tumor in digestive tract, intracranial tumour, brain metastasis, or tumor lympha is carried down shifting, sonCervical carcinomaOral cavityTumour,NerveSystem tumor.Additionally it is applied to heap soil or fertilizer over and around the roots of apoplexy phlegm, facial paralysis, hemiplegia, insane chronic, infantile convulsion, lockjaw, anemophlegmatic vertigo, larynx numbness, scrofula tuberculosis, carbuncle swells, traumatic injury, snake bite and insect sting etc..
Cultivated land,Also known as prepared rhizome of rehmannia.It is sweet, tepor.Return liver and kidney channel.Enter blood system, the soft and moist drop of matter.《This Jing meets original》:" prepared rhizome of rehmannia, false firepower steaming is shone, and it is sweet to turn hardship, is the yang aspect of yin, therefore vigour in energy kidney tonifying." modern study proves, the Dihuang polysaccharide contained by prepared rhizome of rehmannia has a significantly immunity antitumor activity, also significant cardiac stimulant, diuresis, liver protection,It is hypoglycemic, anti-proliferate, it is impervious go out, the effect such as anti-inflammatory, antimycotic, anti-radiation.Enrich blood enriching yin, beneficial essence fills out marrow.Cure mainly the deficiency of liver-yin and kidney-yin, soreness and weakness of waist and knees, osteopyrexia and fever, night sweat seminal emission, Heat Diabetes, blood deficiency chlorosis, palpitation and severe palpitation, irregular menstruation, metrostaxis, dizzinessTinnitus, poliosis.
Radix Codonopsis, sweet mild-natured, effect relaxes, and is the product of flat benefit, widely applicable, few side effects, therefore ancients often with replacement ginseng treat some deficiency of vital energy mild and chronic disease person.The effect of Radix Codonopsis has " bowl spares, beneficial gas are promoted the production of body fluid, invigorating the spleen, beneficial lung, relieving thirst and restlessness ", can be used for the diseases such as spleen and lung weakness, shortness of breath palpitations, anorexia and loose stool, virtual asthma cough, Heat Diabetes.Radix Codonopsis also contains reducing blood lipid, blood pressure, the stifled material of the blood that disappears, so as to the prevention effect that all has some improvement to coronary heart disease and cardiovascular patient.There is regulation cardio-cerebrovascular function, promote the effect of cardio-cerebrovascular health;Particularly there is hematopoiesis, adjust blood pressure, reduce blood pressure, promote blood in human body in liquid to circulate, while also hematopoiesis regeneration, promotes the effect of red blood cell growth.So as to effectively help people to strengthen body immunity, fitness is improved.Radix Codonopsis is not only able to tonifying Qi, and can also balance digestive system.Drinking the soup that Radix Codonopsis boils can promote gastrointestinal disturbances, and the secretion of gastric juice.So as to allow people to be not only able to have a very good appetite, and can also the gastrointestinal disease such as preventing gastric ulcer generation, the immunocompetence for making human body rises, and reduces the incidence of human body diseases.Additionally, according to scientific investigations showed that, after taking Radix Codonopsis, can help improve learning ability, and there is pneumostatic of calming the nerves, improve the health care of sleep the effect of quality.
Date, also known as red date, dry jujube, Chinese date etc., there is the title of the king of all kinds of fruits.There are tonifying middle-Jiao and Qi, nourishing blood and tranquilization, strengthening the spleen and stomach.For spleen eating less, weak loose stool, hysteria of womam.It is the good health nutrient of the patient such as weakness of the spleen and the stomach, insufficiency of vital energy and blood, lassitude, insomnia.Date is rich in the composition such as protein, fat, carbohydrate, carrotene, B family vitamins, vitamin C, citrin and phosphorus, calcium, iron, wherein ascorbic content comes out at the top in fruit, the laudatory title for having vitamin C.Date can improve body immunity, and can inhibition cancer cell.Pharmacological research finds that red date can promote the generation of leucocyte, reduce serum cholesterol to improve seralbumin, protect liver.Date red date is rich in the nutrient content such as protein, fat, carbohydrate, carrotene, B family vitamins, vitamin C, citrin and calcium, phosphorus, iron and CAMP.Really(Date):Tonifying middle-Jiao and Qi, nourishing blood and tranquilization.For spleen eating less, weak loose stool, hysteria of womam.Bark:Anti-inflammatory, hemostasis, antidiarrheal.For tracheitis, enteritis, dysentery, uterine bleeding;Traumatism and bleeding is controlled in external application.Root:Promoting the circulation of qi, promoting blood circulation, menstruation regulating.It is red to collapse for irregular menstruation, leukorrhea.Date has good therapeutic effect to diseases such as acute, chronic hepatitis, cirrhosis, anaemia, anaphylactoid purpuras.Date contains triterpene compound and CAMP,There are stronger suppression cancer, anti-allergic effects.The CAMP that date is rich in, is the required material of human energy metabolism, can strengthen muscular strength, dispelling fatigue, expansion of blood vessels, increase myocardial contractive power, improves myocardial nutrition, is played the role of to prevention and cure of cardiovascular disease good.The effects such as date has tonify deficiency benefit health, nourishing blood and tranquilization, strengthening the spleen and stomach, is the good health nutrient of the patient such as weakness of the spleen and the stomach, insufficiency of vital energy and blood, lassitude, insomnia.The coptis,Nature and flavorEffect:It is bitter, cold in nature.Heat-clearing and damp-drying drug, purging intense heat and detonicating.It is clinicalUsing:Suitable for various arsine knurls, such as liver, courage tumour, tongue cancer, lip cancer, the cancer of the esophagus,Cancer of the stomach, carcinoma of urinary bladder etc..Additionally, apply also for unconsciousness due to high fever, haematemesis, bleeding from five sense organs or subcutaneous tissue, furuncle swelling toxin, the disease such as wet sore itch, acute conjunctivitis, aphtha, bacillary dysentery, acute bowel helmet are scorching, heat contains vexed, feeling of fullness, quenches one's thirst, burn.
Honey,Effect of honey and effect:1. the good merchantable brand of cardiovascular patient,HoneyThe composition of blood can be improved, promote heart and brain and vascular function, therefore Jing informal dresses very good for cardiovascular patient;2. protect liver, honey to have protective effect to liver, liver cell regeneration can be promoted, the formation to fatty liver has certain inhibitory action;3. build up resistance, edible honey can regain one's strength of body rapidly, dispelling fatigue builds up one's resistance to disease;4. sterilized, honey also has sterilized effect, Jing often to eat honey, not only without prejudice to tooth, moreover it is possible to play a part of sterilizing in oral cavity, honey can treat the skin damage of moderate, particularly scald, when honey is regarded into skin wound dressing, bacterium cannot grow;5. promote sleep, the people of the insomnia oral 1 soupspoon honey (in 1 glass of warm water of addition) before sleep daily to help fall asleep as early as possible;6. promote gastrointestinal peristalsis, honey to have adjustment effect to gastrointestinal function, gastric acid secretion can be made normal.Zoopery confirms that honey plays the role of to strengthen enterocinesia, can significantly shorten defecation time.
The effect of the present invention
Cure mainly:The cancer of the esophagus, particularly the early stage cancer of the esophagus, with very low cost, fundamentally improve physical function, and control tumour continues to overgrow and makes it that final disappearance is gradually reduced, so as to recover healthy.
It is simultaneous to control:The cancer in digestive system such as throat cancer, cardiac cancer, pylorus cancer, cancer of the stomach, colorectal cancer.
Our the characteristics of is:
1st, flavour of a drug are more, and dosage is moderate, do not waste.
2nd, selected flavour of a drug are all to be proved that for cancer the cancer of the esophagus particularly can be treated by modern medicine pharmacological evaluation.And then always have in existing proved recipe for cancer, folk prescription --- even more than medicine more than half be all not by modern medicine pharmacological evaluation proved function for cancer and effect.Really it is that the traditional Chinese medical science is seen a doctor by rule of thumb, folk prescription is cured the disease by risk!
3rd, for focus, arrow arrow punching, i.e., selected flavour of a drug all especially grow tender of and hit the bull's eye, and As the medicine took effect, the symptoms lessened.As long as rather than it is for cancer, just jump on the bandwagon, be as a result that " dragon " does not harness the river on the contrary more.
4th, as much as possible " neutralisation ", i.e., selected flavour of a drug generally keep " neutrality ", do not tremble with fear not dry, not hot not cool.Patient can be thus set to suffer less within the cycle of whole medication, pull the devil by the tail less.And if really there is the situation of " getting angry " or " under let out ", then can be directed to concrete individual concrete condition completely, a bit " stopping leak ", the medicine of " fall fire " are specifically solved for interim addition.Rather than imagine at the very start patient may on tell or drop, and some unnecessary medicines are added to prescription, patient is all taken always during very long very long medication, ultimately cause adverse consequences.
Specific embodiment:Oldenlandia diffusa 30g, Sculellaria barbata 30g, salvia chinensis 10g, pseudo-ginseng 7g, seed of Chinese dodder 15g, airpotato yam 7g, rhizoma arisaematis 5g, cultivated land 20g, 7 pieces of date are respectively amplified into 10 times, after clean water, it is placed in BT-2 stainless steels to extract in kettle, plus after 7-9 times of running water, it is heated to 100 DEG C of constant temperature to extract 1 hour or so, extraction fluid, pressure filtration, filtrate is standby.Extract for second:Add in kettle the 5-7 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract or so half an hour, extraction fluid, pressure filtration, filtrate is standby.Third time is extracted:Add in kettle the 3-5 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract 20 minutes or so, extraction fluid, pressure filtration, filtrate is standby.Concentration:The extract of three times is merged, is placed in B-500 type triple effect vacuum high energy evaporation concentrators, reduced pressure (negative 200mmHg), be heated to 80 DEG C, be concentrated into relative density 1.10~1.20, it is standby.Powder processed:Radix Codonopsis 15g, coptis 3g are respectively amplified 10 times, it is end together to crush, and crosses 100 mesh sieves, standby.Dispensing:In 300,000 grades of dust proof workshops, above-mentioned medicinal powder is put in mixer together with aforementioned concentrate and 30g honey and is sufficiently mixed, stir.Drying, crushing:The spice being well mixed is placed in into 60-70 DEG C of baking 4-5 hour in baking oven, is then crushed, cross 100 mesh sieves.Granulation:The spice being well mixed is inserted in comminutor and is granulated.Whole grain:The particle for making is carried out into whole grain, 35 mesh sieves are crossed.It is dried:Whole good particle is inserted in heat circulation drying oven, aeration-drying is to moisture < 8% at 80 DEG C.Packaging:First the pill for making is fitted into vinyon pouch, every bag of 8-10g, then the pouch mounted box for installing, vanning, sterilizing (are adopted into 60Co irradiation, irradiation dose is 8kGy).Finally, irradiated finished product is put in storage by the principle of first in first out.

Claims (2)

1. herbvore pipe Kangai Granula of Hui ethnic group's Chinese medicine tongue and preparation method thereof, it is characterised in that it is by made by the raw material of following weight proportion:
Oldenlandia diffusa 30g, Sculellaria barbata 30g, salvia chinensis 10g, pseudo-ginseng 7g,
Seed of Chinese dodder 15g, airpotato yam 7g, rhizoma arisaematis 5g, cultivated land 20g,
Radix Codonopsis 15g, 7 pieces of date, coptis 3g, honey 30g
This side is the substantially square of one decoction on the one, in practical application, can also increase the 1-3 taste traditional Chinese medical science " harmony between man and nature, dialectical treatmert " theory according to the physique of patient and conditionsDialectical compatibility " medicine.
2. the weight proportion of the herbvore pipe Kangai Granula of Hui ethnic group's Chinese medicine tongue according to claim 1, it is characterised in that including following preparation processes:
A, extract preparation
(1), extract
A, for the first time extraction:By the weight of said herbal medicine in addition to Radix Codonopsis, the coptis, honey, all amplify 10 times, after clean water, it is placed in BT-2 stainless steels to extract in kettle, plus after 7-9 times of running water, is heated to 100 DEG C of constant temperature and extracts 1 hour or so, extraction fluid, pressure filtration, filtrate is standby;
B, second extraction:Add in kettle the 5-7 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract or so half an hour, extraction fluid, pressure filtration, filtrate is standby;
C, third time are extracted:Add in kettle the 3-5 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract 20 minutes or so, extraction fluid, pressure filtration, filtrate is standby;
(2), concentration
The extract of three times is merged, is placed in B-500 type triple effect vacuum high energy evaporation concentrators, reduced pressure (negative 200mmHg), be heated to 80 DEG C, be concentrated into relative density 1.10~1.20, it is standby;
(3), powder processed
Radix Codonopsis 15g, coptis 3g are amplified into 10 times, it is end together to crush, cross 100 mesh sieves, it is standby;
(4), dispensing
In 300,000 grades of dust proof workshops, above-mentioned medicinal powder is put in mixer together with aforementioned concentrate and 30g honey and is sufficiently mixed, stir;
(5) drying, crushing
The spice being well mixed is placed in into 60-70 DEG C of baking 4-5 hour in baking oven, is then crushed, cross 100 mesh sieves;
(6) granulate
The spice being well mixed is inserted in comminutor and is granulated;
(7) whole grain
The particle for making is carried out into whole grain, 35 mesh sieves are crossed;
(8) it is dried
Whole good particle is inserted in heat circulation drying oven, aeration-drying is to moisture < 8% at 80 DEG C;
B, packaging
First the particle for making is fitted into vinyon pouch, every bag of 8-10g, then the pouch mounted box for installing, vanning, sterilizing (are adopted into 60Co irradiation, irradiation dose is 8kGy);
C, warehouse-in
Irradiated finished product is put in storage by the principle of first in first out.
CN201510750654.0A 2015-11-08 2015-11-08 Hui-nationality traditional Chinese medicine granule with herba hedyotidis diffusae for resisting esophagus cancer and preparation method thereof Withdrawn CN106668421A (en)

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Application publication date: 20170517