CN106668498A - Hui-nationality Chinese herbal rhizoma cyperi-fiveleaf akebia fruit gastric cancer-treating pill and preparation method thereof - Google Patents

Abstract

The invention discloses a formula of a Hui-nationality Chinese herbal rhizoma cyperi-fiveleaf akebia fruit gastric cancer-treating pill and a preparation method thereof. The medicine is a green high-tech Chinese herbal medicine for treating late gastric cancer, especially late gastric cancer which cannot be operated due to various reasons. The preparation method comprises the following steps: mixing Chinese herbal medicines such as radix astragali, radix codonopsis, salvia chinensis, seaweed, rhizoma polygonati, rhizoma cyperi, Herba Pteridis multifidae, etc. according to a certain ratio, adding water and decocting, extracting, concentrating and pelleting to obtain traditional Chinese medicine pills, which are used for mainly treating gastric cancer as well as treating digestive cancers such as pharyngolaryngeal cancer, esophagus cancer, cardiac carcinoma, colorectal cancer, etc. The invention has the characteristics of less medicinal odour and moderate dosage. The selected medicines are proved through pharmacology experiments of modern medicine to be capable of treating cancers.

Description

The attached letter gastric cancer of Hui ethnic group's Chinese medicine disappears ball and preparation method thereof

Technical field

Hui ethnic group's Chinese medicine according to the present invention " attached letter gastric cancer disappear ball " is a kind of to treat late gastric cancer especially because the green high-tech Chinese herbal medicine of late gastric cancer that cannot be performed the operation of a variety of causes.The invention further relates to the preparation method of the medicine, belongs to Chinese medicine class.

Background technology

According to《China's tumour registration annual report in 2014》Data display, according to China's Life Calculation of 74 years old for each person, the probability that Chinese suffer from malignant tumor in all one's life is 22%, and average minute clock has 6 people to be diagnosed as malignant tumor, and tumor has become a kind of common disease in China.At present the cancer patient of China is about ten thousand people more than 700, and every year with the speed of more than 100 ten thousand people in increase.And the whole world

According to statistics, in the cancer patient of China nearly 8,000,000, have 31.27% for digestive system cancer patient, wherein patients with gastric cancer accounts for the 41.83% of digestive system cancer patient, almost half.

China is one of incidence gastric cancer rate highest country, and the whole world is annual newly to send out patients with gastric cancer more than 100 ten thousand, and China just account for 42%, and death toll China has accounted for 35%, and the M ＆ M of Chinese gastric cancer is world average level more than 2 times！Inherited genetic factorss among these, immune factor, helicobacter pylori infections factor are all nothing difficult, and most anxious is then environment and dietary factor ...

The early symptom of gastric cancer is not obvious, generally needs time of 2 years or so from incidence gastric cancer to finding tumor, therefore often ignored, once and to standing, most likely reach an advanced stage.

It is operation to control gastric cancer the best way at present, postoperative to be also performed to chemotherapy, and chemotherapy not only large side effects, patient suffering is difficult to stand, and success rate is also very low, 1 year life cycle after most Chemotherapy in Patients less than --- certainly this is also relevant with the over-treatment given birth to without skilful doctor.And on the other hand, although some are detected to be gastric cancer, because a variety of causes cannot be performed the operation,Can only palliative treatment, expect that miracle comes ...

Gastric cancer is disease at present compared with refractory more, but refractory is not represented and cannot controlled, and in addition to above-mentioned western medical treatment method, the traditional Chinese medical science also has many effectively Therapeutic Method.The traditional Chinese medical science, according to the whole body feature determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs of patient, goes for various each phase cancer with organic conception.The advantage of Chinese medicine cancer is to be conducive to stablizing the state of an illness, and toxic and side effects are slight, symptom improves more apparent, slows down PD, tumor regression or the longer-term existence of band tumor, and patient is easy to receive and expense is than less expensive.At present doctor trained in Western medicine is also considered as Chinese medicine can contribute to reducing the toxicity of Radiotherapy chemotherapy as the auxiliary treatment of cancer, improve cancer related symptoms, improve life quality, extend life cycle.But exist problem be the traditional Chinese medical science prescription uniformity it is poor, treatment mainly be experience.From in terms of existing proved recipe for cancer, folk prescription, always there is --- majority is more than more than half --- medicine to be all not prove " compatibility " medicine of function for cancer and effect " determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs " by modern medicine pharmacological evaluation in selected Chinese herbal medicine medical material, inventors believe that very improper；And folk prescription, folk prescription cure the disease lean on be test, often stop over the time cured the disease.

The content of the invention

The purpose of the present invention, be aiming at Cancer in China patient assessment be difficult to and the traditional Chinese medical science see a doctor standardization it is poor, it is repeatable it is poor, lack high level evidence-based medicine EBM theory and evidence, thus the situation for waiting deficiency by rule of thumb that is mainly for cancer, propose a kind of new dosage and preparation method, there is provided a kind of from the beginning of prevention, the sickness rate of gastric cancer is reduced, starts to slow down its tempo from canceration, the green high-tech Chinese herbal medicine for inducing its atrophy apoptosis is started from tumor.Specifically, the present invention one be particularly suited for use in treatment cancer before larger gastric ulcer in case its canceration, two is the especially big gastric ulcer that can treat the gastric cancer initial stage, in case it continues to deteriorate, three are can induce into the cancerous protuberance atrophy apoptosis of tumor, with very low cost, fundamentally improve physical function, so as to get well.Its sharpest edges are to greatest extent to induce self apoptosis of cancerous cell and differentiation, promote cancerous protuberance progressively atrophy.In specific formula, also coordinate determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, according to the origin cause of formation of gastric cancer because dietary factor makes nutrient disequilibrium cause immunologic hypofunction, because Helicobacter pylori infection causes stomach normal cell to be compromised, apoptosis, gastritis, digestive tract ulcer, lymphoproliferative gastric lymphoma " is taken advantage of a weak point " evil poison positive pressure, flee meridians visitor the characteristics of internal organs form long product and cause the basic pathology pathogenesis such as stomach cancer metastasis because evil poison being tied in sick protracted blood stasises and being wrapped blood stasis and is taken advantage of a weak point in opponent's defence, with the method for tonifying speen and tonifying kidney strengthening vital QI to eliminate pathogenic factors reinforcement and elimination in combination, to correct healthy energy interior-deficiency, poly- and internal organs imbalance of YIN and YANG function reduction the deficiency of the solidifying poison of heresy, adjust and improve the immunologic function of body.Simultaneously according to the concrete condition of patient, different formula, or soothing liver-QI stomach function regulating, sending down the abnormal ascending QI pain relieving, or detoxification and removing stasis, clearing away heat and nourishing YIN, or warming spleen and stomach for dispelling cold, invigorating the spleen and regulating the stomach, or strongly invigorating QI and blood are respectively adopted, strengthening spleen, tonifying kidney ... is reachingReinforcement and elimination in combination, reinforcing and reducing and use, the purpose of overall tumor suppression, so as to improve the overall curative effect and late result of curing gastric cancer, a kind of green high-tech Chinese herbal medicine formula and compound method that function for cancer and effect are proved by modern medicine pharmacological evaluation is provided for patients with gastric cancer, with very low or relatively low cost, fundamentally improve physical function, the deterioration of symptom management simultaneously makes the state of an illness gradually take a turn for the better, and finally recovers healthy.Thus also to patient one select different treatment methods or several method to share particularly Chinese and western medicine to combine the leeway of Comprehensive Treatment application to consider according to the personal state of an illness, economic situation, personal inclination, to obtaining optimum curative effect, survival rate is easily improved --- particularly more than 5 years survival rates.

Technical scheme proposed by the invention is：

First, Hui ethnic group's Chinese medicine " attached letter gastric cancer disappear ball " of described treatment gastric cancer and preparation method thereof, is by made by following weight proportion raw material：

Radix Astragali 20g, Radix Codonopsis 9g, Herba Salviae Chinensiss 9g, Sargassum 15g

Rhizoma Polygonati 15g, Radix Linderae 3g, Fructus Akebiae 20g, Rhizoma Cyperi 7g,

Aloe 20g, Herba Pteridis Multifidae 20g, Fructus Lycopersici esculenti 50g

This side is substantially square for one decoction on the one.In practical application, also 1-3 tastes " dialectical compatibility " medicine can be increased according to the body constitution of patient and conditions.

In view of with this, basic side's decoction decoction amount is big, taste is not good enough, patient is difficult to drink, therefore must be prepared using special process.

2nd, it is by the preparation method that above-mentioned each raw material makes medicine pill of the present invention：

A, extract preparation

（1）, extract

A, for the first time extraction：By the weight of said herbal medicine in addition to Radix Codonopsis, the Radix Linderae, Rhizoma Cyperi, Fructus Lycopersici esculenti, all amplify 10 times, after clean water, it is placed in BT-2 rustless steels to extract in kettle, plus after 7-9 times of tap water, is heated to 100 DEG C of constant temperature and extracts 1 hour or so, extraction fluid, pressure filtration, filtrate is standby.

B, second extraction：Add in kettle the 5-7 times of tap water measured toward extracting, be heated to 100 DEG C of constant temperature and extract or so half an hour, extraction fluid, pressure filtration, filtrate is standby.

C, third time are extracted：Add in kettle the 3-5 times of tap water measured toward extracting, be heated to 100 DEG C of constant temperature and extract 20 minutes or so, extraction fluid, pressure filtration, filtrate is standby.

（2）, concentration

The extracting solution of three times is merged, is placed in B-500 type triple effect vacuum high energy evaporation concentrators, reduced pressure (negative 200mmHg), be heated to 80 DEG C, be concentrated into relative density 1.10～1.20, it is standby.

（3）, powder processed

Radix Codonopsis 9g, Radix Linderae 3g, Rhizoma Cyperi 7g are amplified into 10 times, it is end together to crush, cross 80 mesh sieves, it is standby.

（4）, dispensing

In 300,000 grades of dust proof workshops, medicated powder is put in mixer together with aforementioned concentrate and is sufficiently mixed, stir.

(5), drying, crushing

The spice of mix homogeneously is placed in into 60-70 DEG C of baking 4-5 hour in baking oven, is then crushed, cross 100 mesh sieves.

(6), pelletize

The spice of mix homogeneously is inserted into pelletize in comminutor.

(7), granulate

The granule for making is carried out into granulate, 35 mesh sieves are crossed.

(8), it is dried

Whole good granule is inserted in heat circulation drying oven, aeration-drying is to moisture ＜ 8% at 80 DEG C.

(9) pill

Dry mixed gained medicine is put into pill in Chinese medicinal pills preparing machine, pill is optimal with below 4mm.

B, packaging

First pack, the pill by made by is fitted in polyethylene plastic bag, every bag of 8g.Then the pouch mounted box for installing, vanning, sterilizing (are adopted into 60Co irradiation, irradiation dose is 8kGy）.

C, warehouse-in

Irradiated finished product is put in storage by the principle of first in first out.

Routine instructions of taking of the invention：Above-mentioned pill three times a day, per 1 bag of 8g, on an empty stomach (taking half an hour after can not drink water in a large number, in order to avoid water down medicinal liquid).The pungent grade food larger to gastrointestinal irritation is not eaten during medication.This medicine is a course for the treatment of in three months, typically takes two to three courses for the treatment of, at most takes four courses for the treatment of.

This medicine does extra conductant ingredient and takes better with pan-fried tomato soup.The specific practice of pan-fried tomato soup is：Take from so well-done little tomato（50 grams or so）Chopping, puts 10 grams or so vegetable oil in pot, heat, and is put into appropriate Flos Allii Fistulosi, Sal, pours into be decocted in pot by the Fructus Lycopersici esculenti of chopping when Flos Allii Fistulosi blows out fragrance and fries 1-2 minutes, then infuses to be got away into suitable quantity of water and take the dish out of the pot.The pungent grade food larger to gastrointestinal irritation is not eaten during medication.

The effect of each raw material of the present invention：

The Radix Astragali,The Radix Astragali is sweet, tepor.Returns spleen, lung meridian.Spleen reinforcing lung qi, ascending up spleen-Qi and Yang, benefit defends consolidating superficial resistance, diuresis, promoting pus discharge and tissue regeneration strengthening.The Radix Astragali is the dry root of leguminous plant Radix Astagali Radix Astragali.Containing aminoacid, phlegmatic temperament, saccharide, bitter principle, choline glycine betaine Folic Acid, kumatakenin, cupreol（, astragalus polysaccharidess etc..It is allCancerPatient because caused by deficiency of both the splenic and pulmonary QI complexion white light it is white, lassitude, anorexia loose stool, hematemesis hematochezia, cough with asthma shortness of breath, abundant expectoration is dilute white, deficiency of QI with disinclination to talk, weak spontaneous perspiration, palpitation and insomnia, fever due to deficiency of QI, and edema oliguria etc. can use it.The Radix Astragali can strengthen the phagocytic function of reticuloendothelial system, have facilitation to interferon system, have completeness Immunonormalizing action to cancer patient lymphocytes' function, have fabulous curative effect to precancerous lesion gastric ulcer.

Radix Codonopsis,Effect and effect：" invigorating the spleen and replenishing QI, promotes the production of body fluid, spleen invigorating, and taste, relieving thirst and restlessness." traditional Chinese medical science thinks Radix Codonopsis flat property and sweet taste, returns spleen, lung meridian, the effect of have invigorating the spleen and replenishing QI, strengthening spleen and tonifying lung, can be used for the diseases such as deficiency of the spleen and lung, shortness of breath palpitations, anorexia and loose stool, virtual asthma cough, Heat Diabetes.And newest scientific research discovery, the various nutrient substance contained in Radix Codonopsis, the body immunity to people, blood vessel, and other organs are helpful.Radix Codonopsis can promote blood in human body in liquid to circulate, while also hemopoietic regeneration, promotes the effect of red blood cell growth.So as to effectively help people to strengthen body immunity, body constitution is improved.Radix Codonopsis has good opsonic action to the digestive system of people.Not only when pathological changes has occurred in the digestive system of people, disease can be treated using Radix Codonopsis, such as can be nursed one's health by taking Radix Codonopsis decoct when the gastroxia of people, and, usually some Radix Codonopsis just can in advance be taken when, to prevent the disease of digestive system, and the health of facilitating digestion system.Because Radix Codonopsis also has certain opsonic action to the immune system of people, therefore some Radix Codonopsis products are eaten, the immunocompetence that can make the person rises, and reduces the incidence rate of human body diseases.Except, Radix Codonopsis also adjusts cardio-cerebrovascular function, promotes the effect of cardio-cerebrovascular health;Particularly there is hemopoietic, blood pressure, the effect of reducing blood pressure etc. is adjusted.

Herba Salviae Chinensiss,For the herb of Labiatae annual herb plant Herba Salviae Chinensiss, flavor efficacy：It is bitter in the mouth, mild-natured.Heat-clearing and toxic substances removing, cool blood flat liver, inducing diuresis to remove edema, eliminating stagnation.Clinical practice：It is usually used in treating the esophageal carcinoma, carcinoma of parotid gland, hepatocarcinoma, gastric cancer, carcinoma of gastric cardia etc..Medical science religion ' educate net compile additionally, be additionally operable to treat viral hepatitis, summer-heat dysentery, infantile acute nephritis, edema, rheumatic arthritis, chyluria, treating swelling and pain by traumatic injury, venom, furuncle swell and ache, metrorrhagia etc..

Sargassum,Meridian distribution of property and flavor：It is salty, tremble with fear.Returns spleen, liver and kidney channel.Effect：Eliminating phlegm and softening indurated mass eliminating stagnation, inducing diuresis to remove edema, inducing diuresis to remove edema has the effects such as lipidemia disease, blood pressure lowering, anticoagulant, antiulcer, regulation immunity, antitumor.There is inhibitory action to bacillus subtilis, herpes simplex virus.Modern study proves Sargassum because containing iodide, property thyromegaly has therapeutical effect where causing to iodine deficiency；And to hyperthyroidism, basal metabolic rate increases temporary transient inhibitory action.Phycocolloid acid sulfuric ester in Sargassum has anti-hyperlipidemia to act on.Additionally, this product has inhibitory action to Bacillus tuberculosis, influenza virus and dermatophytess.

Rhizoma Polygonati,For the dry rhizome of liliaceous plant P. kingianum, Rhizoma Polygonati or Polygonatum cyrtonema Hua.Nature and flavor：It is sweet；It is flat.Return through：Spleen channel；Lung meridian；Kidney channel.Effect：Nourishing YIN and moistening the lung；Invigorating the spleen and replenishing QI, Zishen fill fine.There is nourishing YIN and moistening the lung；Invigorating the spleen and replenishing QI, effect of Zishen fill fine.Often match somebody with somebody GANMAI DAZAO TANG, hyperkinetic syndrome, neurosiss are controlled in Radix Paeoniae easing the affected liver nourishing heart.With supplementing QI and nourishing YIN such as the Radix Astragali, Concha Ostreae, the Radixs Linderae, pathogenic fire purging is purged heat, and controls hyperthyroidism.With Fructus Crataegi, Fructus Lycii, Fructus Ligustri Lucidi, Radix Salviae Miltiorrhizae is controlled in metabolism and disease.And prevent and treat arteriosclerosis, slow down aging.Cure mainly：Deficiency of YIN chronic cough；Xeropulmonary cough；It is insufficiency of the spleen weak；Few dry of food；Quench one's thirst；Deficiency of the kidney soreness of the waist and knees；Impotence and seminal emission；Tinnitus mesh is dark；Early whitening of beard and hair；Body void is won thin；Wind favus disease.Effect：There is Rhizoma Polygonati blood pressure lowering, blood sugar lowering, blood fat reducing, atherosclerosis, slow down aging and antibacterial etc. to act on, and polygonatum polysaccharide has Immunestimulatory effect.For lung-dryness syndrome due to deficiency of YIN, the few expectorant of dry cough, and the chronic cough chronic cough of YIN-deficiency of the lung and kidney etc..For weakness of the spleen and stomach.Both tonifying spleen-yin, and strengthening the spleen gas, obtains dizzy for deficiency of kidney essence, soreness of the waist and knees, early whitening of beard and hair and quenches one's thirst.

The Radix Linderae,Flavor efficacy： Ye Xin, it is warm in nature.Warming spleen and stomach for dispelling cold, regulating QI to relieve pain.Clinical practice：Closely it is used for digestive tract tumor, such asGastric cancer, intestinal cancer, be additionally operable to bladder cancer etc..Additionally, being additionally operable toTreatmentHeart peratodynia, vomiting and diarrhoeaStomachache、Dysmenorrhea, colic, frequent micturition, rheumatalgia, traumatic pain and traumatic hemorrhage.

Fructus Akebiae,ForLardizabalaceaePlantCaulis Akebiae threeleaf akebiaOrCaulis AkebiaeDry mature fruit.Sweet in the mouth, cold in nature, function isDepressed liver-energy dispersing and QI regulating, promoting blood circulation and stopping pain, relieving restlessness diuresis.Cure mainlyStomachache due to hyperactive liver-QI attacking the stomach、Gastric heatFood is slow-witted, excessive thirst,Dysentery、Lumbago、Hypochondriac pain, hernia etc..The less single of Fructus Akebiae is used for kinds of tumors with his medicine phases 5 more with controlling in tumor, and has preferable curative effect more.

Rhizoma Cyperi,For the dry tuber of Cyperaceae herbaceous plant dried tuber for many years.Nature and flavor：It is pungent, slight bitter, flat.Return through：Enter liver, tri-jiao channel.Function：Regulate the flow of vital energy Xie Yu, regulating menstruation, pain relieving.Cure mainly：The diseases such as incoordination between the liver and stomach, depression of QI, distension and fullness of the chest and abdomen, menoxenia, dysmenorrhea.Main component：Containing volatile oil, wherein predominantly Rhizoma Cyperi is dilute, cyperol, and fatty acids etc..Effect and effect：Regulate the flow of vital energy Xie Yu, menstruction regulating and pain relieving.Its pharmacological research must be also not enough.Modern experimental tentatively finds have：Analgesic activity.The ethanol extract of Rhizoma Cyperi can significantly increase laboratory animal（White mice）The threshold of pain.Clinical practice：Front people's this product is called " Directorate-General DG of disorder of QI, the chief commander of female section ", and the pain being widely used in caused by the stagnation of QI such as belongs to costalgia caused by stagnation of liver-QI（It is more common in chronic hepatitiss）, such as gastral cavilty pain due to disorder of QI has acid regurgitation vomiting concurrently, eructation and poor appetite, additionally, hypochondriac pain caused by the disease due to latent summer-heat pathogen is wet, or cough or do not cough, without cold but hectic fever, can be strongly fragrant with circulation of qi promoting soothing liver-QIization such as Flos Inulae, diseases caused by exogenous pathogenic factor and the person that has depression of liver-QI concurrently, can with Rhizoma Cyperi,Folium PerillaeDeng diaphoresis resolving depression pain relieving, such as fragrant Soviet Union's drink.Especially gynecological diseases and menoxenia, witness has stagnation of QI due to depression of the liver, with psychoneural factor（Such as it is in a very depressed state or irascible, psychentonia）Relevant menstrual pain is preferably.

Aloe,Nature and flavorEffect：Bitter in the mouth, it is cold in nature.Heat clearing away, relieving constipation;Parasite killing.It is clinicalUsing：Aloe is usually used in gastroenteric tumorTreatment, such as hepatocarcinoma, cancer of pancreas.Additionally, be additionally operable to treat Liver Channel excess-heat dizziness, headache, tinnitus, agitation,Constipation, pediatric epilepsy scared, infantile malnutrition.Dental caries, furuncle carbuncle tumor, burn and scald, exudative dermatitis are controlled in leaf external.

Herba Pteridis Multifidae,Containing flavonoid, sterol, ammonia its acid, lactone, phenols and tannin.The property of medicine is bitter, cold.Return liver, stomach, lung, large intestine, bladder warp.Drug effect internal heat anticance, removing damp-heat, cooling blood for hemostasis.It is medicinal：（1）Internal heat anticance, for carcinoma product poison：Gastric cancer, rectal cancer, pulmonary carcinoma etc.；（2）The evanescence of heat that disappears is wet, for damp and hot inflammation：Acute hepatitises etc.；（3）Cooling blood for hemostasis, for heat in blood bleeding：Heat in blood hematuria etc..

Fructus Lycopersici esculenti,Fructus Lycopersici esculenti has fat-reducing Weight reducing , allaying tiredness, appetite stimulator, raising to the digestion of protein, reduce flatulence food stagnation the effects such as.In recent years, in the anti-cancer or health food that numerous worldwide organizations are recommended, Fructus Lycopersici esculenti always ranks among the best.Find in substantial amounts of epidemiological survey and zoopery, outstanding representation of the Fructus Lycopersici esculenti in cancer-resisting is mostly derived from lycopene therein.So, lycopene be how to give protection against cancer, the first of anticancer, by a series of biochemical action, lycopene can promote Carcinoma cell differentiation (to good direction conversion), anticancer propagation.Second, immune function of human body can be strengthened.Lycopene can promote some to have anti-cancer, the such as secretion of the cytokines of antitumaous effect, interleukin-II, dissolution of the activated lymphocyte to cancerous cell；The lymphocyte being activated can discharge cytokines such as tumor necrosis factor etc. again, have lethal effect to tumor cell.3rd, lycopene has stronger Antioxidation Effect.The aging of cell, damage are all relevant with Free Radical with canceration, and antioxidant (such as lycopene) is effectively removing free radical, so as to play whole body health-care effect, wherein be just included in protective effect on cancer risk playing an important role.

The effect of the present invention：

Cure mainly：Gastric cancer, especially because a variety of causes cannot carry out the late gastric cancer of Surgery for Gastric Carcinoma, with very low cost, fundamentally improves physical function, and control tumor continues to overgrow and makes it that final disappearance is gradually reduced, so as to recover healthy.

It is simultaneous to control：The cancer in digestive system such as laryngocarcinoma, the esophageal carcinoma, cardiac cancer, pylorus cancer, colorectal cancer.

Our the characteristics of is：

1st, flavour of a drug are more, and dosage is moderate, do not waste.

2nd, selected flavour of a drug are mostly that proved by modern medicine pharmacological evaluation can be for cancer, and existing proved recipe for cancer, then always there are medicines more than half to be all not proved function for cancer and effect by modern medicine pharmacological evaluation in folk prescription.

3rd, for focus, arrow arrow punching, i.e., selected flavour of a drug all especially grow tender of and hit the bull's eye, and As the medicine took effect, the symptoms lessened.As long as rather than it is for cancer, just jump on the bandwagon, being as a result that " dragon " is more bad on the contrary harnesses the river.

4th, as much as possible " neutralization ", i.e., selected flavour of a drug generally keep " neutrality ", do not tremble with fear not dry, not hot not cool.Patient can be thus set to suffer less within the cycle of whole medication, pull the devil by the tail less.And if really there is the situation of " getting angry " or " under let out ", then can be directed to concrete individual concrete condition completely, add a bit " stopping leak ", the medicine of " pathogenic fire reducing " dialectically temporarily and specifically solve.Rather than imagine at the very start patient may on tell or drop, and some unnecessary medicines are added to prescription, patient is all taken always during very long very long medication, ultimately cause adverse consequencess.

Specific embodiment：Radix Astragali 20g, Herba Salviae Chinensiss 9g, Sargassum 15g, Rhizoma Polygonati 15g, Fructus Akebiae 20g, Aloe 20g, Herba Pteridis Multifidae 20g are respectively amplified into 10 times, after clean water, it is placed in BT-2 rustless steels to extract in kettle, plus after 7-9 times of tap water, it is heated to 100 DEG C of constant temperature to extract 1 hour or so, extraction fluid, pressure filtration, filtrate is standby.Extract for second：Add in kettle the 5-7 times of tap water measured toward extracting, be heated to 100 DEG C of constant temperature and extract or so half an hour, extraction fluid, pressure filtration, filtrate is standby.Third time is extracted：Add in kettle the 3-5 times of tap water measured toward extracting, be heated to 100 DEG C of constant temperature and extract 20 minutes or so, extraction fluid, pressure filtration, filtrate is standby.Concentration：The extracting solution of three times is merged, is placed in B-500 type triple effect vacuum high energy evaporation concentrators, reduced pressure (negative 200mmHg), be heated to 80 DEG C, be concentrated into relative density 1.10～1.20, it is standby.Powder processed：Radix Codonopsis 9g, Rhizoma Cyperi 7g, Radix Linderae 3g are respectively amplified into 10 times, it is end together to crush, cross 80 mesh sieves, it is standby.Dispensing：In 300,000 grades of dust proof workshops, medicated powder is put in mixer together with aforementioned concentrate and is sufficiently mixed, stir.Drying, crushing：The spice of mix homogeneously is placed in into 60-70 DEG C of baking 4-5 hour in baking oven, is then crushed, cross 100 mesh sieves.Pelletize：The spice of mix homogeneously is inserted into pelletize in comminutor.Granulate：The granule for making is carried out into granulate, 35 mesh sieves are crossed.It is dried：Whole good granule is inserted in heat circulation drying oven, aeration-drying is to moisture ＜ 8% at 80 DEG C.Pill：Dry mixed gained medicine is put into pill in Chinese medicinal pills preparing machine, pill is optimal with below 4mm.Packaging：

First pack, the pill by made by is fitted in polyethylene plastic bag, every bag of 8g.Then the pouch mounted box for installing, vanning, sterilizing (are adopted into 60Co irradiation, irradiation dose is 8kGy）.Finally, irradiated finished product is put in storage by the principle of first in first out.

Claims (2)

1. the attached letter gastric cancer of Hui ethnic group's Chinese medicine disappears ball and preparation method thereof, it is characterised in that it is by made by the raw material of following weight proportion：

Radix Astragali 20g, Radix Codonopsis 9g, Herba Salviae Chinensiss 9g, Sargassum 15g

Rhizoma Polygonati 15g, Radix Linderae 3g, Fructus Akebiae 20g, Rhizoma Cyperi 7g,

Aloe 20g, Herba Pteridis Multifidae 20g, Fructus Lycopersici esculenti 50g

This side is the substantially square of one decoction on the one, in practical application, can also increase 1-3 tastes " dialectical compatibility " medicine according to the body constitution of patient and conditions.

2. the attached letter gastric cancer of Hui ethnic group's Chinese medicine according to claim 1 disappears the weight proportion of ball, it is characterised in that including following preparation processes：

The preparation of A, extract

（1）, extract

A, for the first time extraction：By the weight of said herbal medicine in addition to Radix Codonopsis, the Radix Linderae, Rhizoma Cyperi, Fructus Lycopersici esculenti, all amplify 10 times, after clean water, it is placed in BT-2 rustless steels to extract in kettle, plus after 7-9 times of tap water, is heated to 100 DEG C of constant temperature and extracts 1 hour or so, extraction fluid, pressure filtration, filtrate is standby；

B, second extraction：Add in kettle the 5-7 times of tap water measured toward extracting, be heated to 100 DEG C of constant temperature and extract or so half an hour, extraction fluid, pressure filtration, filtrate is standby；

C, third time are extracted：Add in kettle the 3-5 times of tap water measured toward extracting, be heated to 100 DEG C of constant temperature and extract 20 minutes or so, extraction fluid, pressure filtration, filtrate is standby；

（2）, concentration

The extracting solution of three times is merged, is placed in B-500 type triple effect vacuum high energy evaporation concentrators, reduced pressure (negative 200mmHg), be heated to 80 DEG C, be concentrated into relative density 1.10～1.20, it is standby；

（3）, powder processed

Radix Codonopsis 9g, Radix Linderae 3g, Rhizoma Cyperi 7g are amplified into 10 times, it is end together to crush, cross 80 mesh sieves, it is standby；

（4）, dispensing

In 300,000 grades of dust proof workshops, medicated powder is put in mixer together with aforementioned concentrate and is sufficiently mixed, stir；

(5), drying, crushing

The spice of mix homogeneously is placed in into 60-70 DEG C of baking 4-5 hour in baking oven, is then crushed, cross 100 mesh sieves；

(6), pelletize

The spice of mix homogeneously is inserted into pelletize in comminutor；

(7), granulate

The granule for making is carried out into granulate, 35 mesh sieves are crossed；

(8), it is dried

Whole good granule is inserted in heat circulation drying oven, aeration-drying is to moisture ＜ 8% at 80 DEG C；

(9) pill

Dry mixed gained medicine is put into pill in Chinese medicinal pills preparing machine, pill is optimal with below 4mm；

B, packaging

First pack, the pill by made by is fitted in polyethylene plastic bag, every bag of 8g；Then the pouch mounted box for installing, vanning, sterilizing (are adopted into 60Co irradiation, irradiation dose is 8kGy）；

C, warehouse-in

Irradiated finished product is put in storage by the principle of first in first out.