CN106668500A - Hui traditional Chinese medicine cyperus rotundus stomach cancer elimination particles and preparation method thereof - Google Patents
Hui traditional Chinese medicine cyperus rotundus stomach cancer elimination particles and preparation method thereof Download PDFInfo
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Abstract
The invention relates to a formula and a preparation method of Hui traditional Chinese medicine cyperus rotundus stomach cancer elimination particles. According to the present invention, the Hui traditional Chinese medicine cyperus rotundus stomach cancer elimination particles are the green high-tech Chinese herb for treating advanced stage stomach cancer, especially advanced stage stomach cancer incapable of being subjected to operation due to various causes; milkvetch root, codonopsis pilosula, salvia chinensis benth, seaweed, polygonatum sibiricum, cyperus rotundus, pteris multifida poir and other Chinese herbs are mixed according to a certain ratio, water is added, and decoction, extraction, concentration and granulation are performed to obtain the traditional Chinese medicine particles; and the Hui traditional Chinese medicine cyperus rotundus stomach cancer elimination particles mainly treat stomach cancer, can further treat throat cancer, esophageal cancer, cardiac cancer, large intestine cancer and other digestive system cancers, and have characteristics of less components and moderate doses, wherein the modern medical pharmacology experiment results prove that the selected medicines can treat cancers.
Description
Technical field
The attached letter cancer of the stomach of Hui ethnic group's Chinese medicine according to the present invention particle that disappears is a kind of to treat late gastric cancer especially because the green high-tech Chinese herbal medicine of late gastric cancer that cannot be performed the operation of a variety of causes.The invention further relates to the preparation method of the medicine, belongs to traditional Chinese medicine class.
Background technology
According to《China's tumour registration annual report in 2014》Data display, according to China for each person 74 years old life-span calculate, Chinese all one's life suffer from malignant tumour probability be 22%, average minute clock has 6 people to be diagnosed as malignant tumour, and tumour has become a kind of common disease in China.At present the cancer patient of China is about ten thousand people more than 700, and every year with the speed of more than 100 ten thousand people in increase.And the whole world
According to statistics, in the cancer patient of China nearly 8,000,000, have 31.27% for Alimentary System patient, wherein patients with gastric cancer accounts for the 41.83% of Alimentary System patient, almost half.
China is one of incidence gastric cancer rate highest country, and the whole world is annual newly to send out patients with gastric cancer more than 100 ten thousand, and China just account for 42%, and death toll China has accounted for 35%, and the M & M of Chinese cancer of the stomach is world average level more than 2 times!Inherent cause among these, immune factor, helicobacter pylori infections factor are all nothing difficult, and most anxious is then environment and dietary factor ...
The early symptom of cancer of the stomach is not obvious, generally needs time of 2 years or so from incidence gastric cancer to finding tumour, therefore often ignored, once and to standing, most likely reach an advanced stage.
It is operation to control cancer of the stomach the best way at present, postoperative to be also performed to chemotherapy, and chemotherapy not only large side effects, patient suffering is difficult to stand, and success rate is also very low, 1 year life cycle after most Chemotherapy in Patients less than --- certainly this is also relevant with the over-treatment given birth to without skilful doctor.And on the other hand, although some are detected to be cancer of the stomach, because a variety of causes cannot be performed the operation,Can only palliative treatment, expect that miracle comes ...
Cancer of the stomach is at present more refractory disease more, but refractory representative cannot be controlled, and in addition to above-mentioned western medical treatment method, the traditional Chinese medical science also has many effectively treatment methods.The traditional Chinese medical science, according to the whole body feature diagnosis and treatment of patient, goes for various each phase cancer with organic conception.The advantage of Chinese medicine cancer is to be conducive to stablizing the state of an illness, and toxic and side effect is slight, symptom improves more apparent, slows down PD, tumor regression or the longer-term existence of band knurl, and patient is easy to receive and expense is than less expensive.At present doctor trained in Western medicine is also considered as traditional Chinese medicine can contribute to reducing the toxicity of Radiotherapy chemotherapy as the auxiliary treatment of cancer, improve cancer related symptoms, improve life quality, extend life cycle.But exist problem be the traditional Chinese medical science prescription uniformity it is poor, treatment mainly be experience.From in terms of existing proved recipe for cancer, folk prescription, always there is --- majority is more than more than half --- medicine to be all not prove " compatibility " medicine of function for cancer and effect " diagnosis and treatment based on an overall analysis of the illness and the patient's condition " by modern medicine pharmacological evaluation in selected Chinese herbal medicine medicinal material, inventors believe that very improper;And folk prescription, folk prescription cure the disease lean on be test, often stop over the time cured the disease.
The content of the invention
The purpose of the present invention, be aiming at Cancer in China patient assessment be difficult to and in the side's of curing the desease poor consistency, repeatable poor, high level evidence-based medicine EBM be theoretical and the relative shortage of evidence,Thus the situation for waiting deficiency by rule of thumb that is mainly for cancer, propose a kind of new dosage and preparation method, there is provided one kind reduces the incidence of disease of cancer of the stomach from the beginning of prevention, start to slow down its tempo from canceration, the green high-tech Chinese herbal medicine for inducing its atrophy apoptosis is started from tumour.Specifically, the present invention one be particularly suited for use in treatment cancer before larger gastric ulcer in case its canceration, two is the especially big gastric ulcer that can treat the cancer of the stomach initial stage, in case it continues to deteriorate, three are can induce into the cancerous swelling atrophy apoptosis of knurl, with very low cost, fundamentally improve physical function, so as to get well.Its sharpest edges are to greatest extent to induce self apoptosis of cancer cell and differentiation, promote cancerous swelling progressively atrophy.In specific formula, also coordinate diagnosis and treatment based on an overall analysis of the illness and the patient's condition, according to the origin cause of formation of cancer of the stomach because dietary factor makes nutrient disequilibrium cause immunologic hypofunction, because Helicobacter pylori infection causes stomach normal cell to be compromised, apoptosis, gastritis, digestive tract ulcer, lymphoproliferative gastric lymphoma " is taken advantage of a weak point " evil poison positive pressure, flee channels and collaterals visitor the characteristics of internal organs form long product and cause the basic pathology interpretation of the cause, onset and process of an illness such as Metastasis of Gastric Cancer because evil poison being tied in sick protracted blood stasis and being wrapped hemostasis and is taken advantage of a weak point in opponent's defence, with the tonifying speen and tonifying kidney strengthening vital QI to eliminate pathogenic factors method that tonification and purgation in combination, it is empty in healthy tendency to correct, poly- and internal organs imbalance of yin and yang function reduction the deficiency of the solidifying poison of heresy, adjust and improve the immunologic function of body.Simultaneously according to the concrete condition of patient, different formulas, or easypro liver and stomach, drop check pain, or detoxification and removing stasis, clearing heat and nourishing yin, or warming spleen and stomach for dispelling cold, strengthening the spleen and stomach, or strongly invigorating QI and blood are respectively adopted, strengthening spleen, tonifying kidney ... is reachingTonification and purgation in combination, reinforcing and reducing methods and use, the purpose of overall tumor suppression, so as to improve the overall curative effect and late result of curing gastric cancer, a kind of green high-tech Chinese herbal medicine formula and compound method that function for cancer and effect are proved by modern medicine pharmacological evaluation is provided for patients with gastric cancer, with very low or relatively low cost, fundamentally improve physical function, the deterioration of symptom management simultaneously makes the state of an illness gradually take a turn for the better, and finally recovers healthy.Thus also to patient one select different treatment methods or several method to share particularly traditional Chinese and western medicine to combine the leeway of complex treatment application to consider according to the personal state of an illness, economic situation, personal inclination, to obtaining optimum curative effect, survival rate is easily improved --- particularly more than 5 years survival rates.
Technical scheme proposed by the invention is:
The attached letter cancer of the stomach of Hui ethnic group's Chinese medicine of the first, described treatment cancer of the stomach disappears particle and preparation method thereof, is by made by following weight proportion raw material:
Radix Astragali 20g, Radix Codonopsis 9g, salvia chinensis 9g, marine alga 15g
Sealwort 15g, root of three-nerved spicebush 3g, fiveleaf akebia fruit 20g, rhizoma cyperi 7g,
Aloe 20g, phoenix-tail fern 20g, tomato 50g
This side is substantially square for one decoction on the one.In practical application, also 1-3 tastes " dialectical compatibility " medicine can be increased according to the physique of patient and conditions.
In view of with this, basic side's decoction decoction of medicinal ingredients amount is big, taste is not good enough, patient is difficult to drink, therefore must be prepared using special process.
2nd, it is by the preparation method that above-mentioned each raw material makes Chinese medicinal granule of the present invention:
A, extract preparation
(1), extract
A, for the first time extraction:By the weight of said herbal medicine in addition to Radix Codonopsis, the root of three-nerved spicebush, rhizoma cyperi, tomato, all amplify 10 times, after clean water, it is placed in BT-2 stainless steels to extract in kettle, plus after 7-9 times of running water, is heated to 100 DEG C of constant temperature and extracts 1 hour or so, extraction fluid, pressure filtration, filtrate is standby.
B, second extraction:Add in kettle the 5-7 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract or so half an hour, extraction fluid, pressure filtration, filtrate is standby.
C, third time are extracted:Add in kettle the 3-5 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract 20 minutes or so, extraction fluid, pressure filtration, filtrate is standby.
(2), concentration
The extract of three times is merged, is placed in B-500 type triple effect vacuum high energy evaporation concentrators, reduced pressure (negative 200mmHg), be heated to 80 DEG C, be concentrated into relative density 1.10~1.20, it is standby.
(3), powder processed
Radix Codonopsis 9g, root of three-nerved spicebush 3g, rhizoma cyperi 7g are amplified into 10 times, it is end together to crush, cross 80 mesh sieves, it is standby.
(4), dispensing
In 300,000 grades of dust proof workshops, medicinal powder is put in mixer together with aforementioned concentrate and is sufficiently mixed, stir.
(5), drying, crushing
The spice being well mixed is placed in into 60-70 DEG C of baking 4-5 hour in baking oven, is then crushed, cross 100 mesh sieves.
(6), granulate
The spice being well mixed is inserted in comminutor and is granulated.
(7), whole grain
The particle for making is carried out into whole grain, 35 mesh sieves are crossed.
(8), it is dried
Whole good particle is inserted in heat circulation drying oven, aeration-drying is to moisture < 8% at 80 DEG C.
B, packaging
First pack, the particle by made by is fitted into polyethylene plastic bag, every bag of 8g.Then the pouch mounted box for installing, vanning, sterilizing (are adopted into 60Co irradiation, irradiation dose is 8kGy).
C, warehouse-in
Irradiated finished product is put in storage by the principle of first in first out.
Routine instructions of taking of the invention:Above-mentioned particle three times a day, per 1 bag of 8g, on an empty stomach (taking half an hour after can not drink water in a large number, in order to avoid water down liquid).The pungent grade food larger to gastrointestinal irritation is not eaten during medication.This medicine is a course for the treatment of in three months, typically takes two to three courses for the treatment of, at most takes four courses for the treatment of.
This medicine does medicine efficacy enhancing ingredient and takes better with pan-fried tomato soup.The specific practice of pan-fried tomato soup is:Take from so well-done little tomato(50 grams or so)Chopping, puts 10 grams or so vegetable oil in pot, heat, and is put into appropriate chopped spring onion, salt, pours into be decocted in pot by the tomato of chopping when chopped spring onion blows out fragrance and fries 1-2 minutes, then infuses to be got away into suitable quantity of water and take the dish out of the pot.The pungent grade food larger to gastrointestinal irritation is not eaten during medication.
The effect of each raw material of the present invention:
The Radix Astragali,The Radix Astragali is sweet, tepor.Returns spleen, lung channel.Tonifying spleen lung qi, yang invigorating, benefit defends solid table, diuresis, promoting pus discharge and tissue regeneration.The Radix Astragali is the dry root of legume astragalus mongolicus Astragalus membranacus.Containing amino acid, mucilaginous substance, carbohydrate, bitter principle, choline glycine betaine folic acid, kumatakenin, cupreol(, astragalus polyose etc..It is allCancerPatient is white because of spleen-lung Qi deficiency caused complexion white light, lassitude, receives few loose stool, and hematemesis hematochezia, cough and asthma shortness of breath, abundant expectoration is dilute white, deficiency of QI with disinclination to talk, weak spontaneous perspiration, palpitation and insomnia, fever due to deficiency of vital energy, and edema oliguria etc. can use it.The Radix Astragali can strengthen the phagocytic function of reticuloendothelial system, have facilitation to interferon system, have completeness Immunonormalizing action to cancer patient lymphocytes' function, have fabulous curative effect to precancerous lesion gastric ulcer.
Radix Codonopsis,Effect and effect:" tonifying middle-Jiao and Qi, promotes the production of body fluid, invigorating the spleen, and taste, relieving thirst and restlessness." traditional Chinese medical science thinks Radix Codonopsis flat property and sweet taste, returns spleen, lung channel, the effect of have tonifying middle-Jiao and Qi, strengthening spleen and tonifying lung, can be used for the diseases such as spleen and lung weakness, shortness of breath palpitations, anorexia and loose stool, virtual asthma cough, Heat Diabetes.And newest scientific research discovery, the various nutriments contained in Radix Codonopsis, the body immunity to people, blood vessel, and other organs are helpful.Radix Codonopsis can promote blood in human body in liquid to circulate, while also hematopoiesis regeneration, promotes the effect of red blood cell growth.So as to effectively help people to strengthen body immunity, fitness is improved.Radix Codonopsis has good opsonic action to the digestive system of people.Not only when pathology has occurred in the digestive system of people, disease can be treated using Radix Codonopsis, such as can be nursed one's health by taking Radix Codonopsis decoction when the gastroxia of people, and, usually some Radix Codonopsis just can in advance be taken when, to prevent the disease of digestive system, and the health for promoting digestive system.Because Radix Codonopsis also has certain opsonic action to the immune system of people, therefore some Radix Codonopsis products are eaten, the immunocompetence that can make the person rises, and reduces the incidence of human body diseases.Except, Radix Codonopsis also adjusts cardio-cerebrovascular function, promotes the effect of cardio-cerebrovascular health;Particularly there is hematopoiesis, blood pressure, the effect of reducing blood pressure etc. is adjusted.
Salvia chinensis,For the herb of Labiatae annual herb plant salvia chinensis, flavor efficacy:It is bitter, mild-natured.It is clearing heat and detoxicating, cool blood flat liver, inducing diuresis for removing edema, dissipating bind.Clinical practice:It is usually used in treating the cancer of the esophagus, carcinoma of parotid gland, liver cancer, cancer of the stomach, cardia cancer etc..Medical science religion ' educate net compile additionally, be additionally operable to treat virus hepatitis, hot summer weather rush down dysentery, infantile acute nephritis, oedema, rheumatic arthritis, chyluria, treating swelling and pain by traumatic injury, venomous snake bite, boil swell and ache, metrorrhagia etc..
Marine alga,Meridian distribution of property and flavor:It is salty, tremble with fear.Returns spleen, liver and kidney channel.Effect:Dissolving phlegm softening and resolving hard mass, inducing diuresis for removing edema, inducing diuresis for removing edema has lipidemia disease, step-down, anti-freezing, antiulcer, adjusts the effect such as immune, antitumor.There is inhibitory action to hay bacillus, herpes simplex virus.Modern study proves marine alga because containing iodide, property Thyroid Gland Swell has therapeutic action where causing to iodine deficiency;And to hyperthyroidism, basal metabolic rate increases temporary transient inhibitory action.Phycocolloid acid sulfuric ester in marine alga has anti-hyperlipidemia to act on.Additionally, this product has inhibitory action to Bacillus tuberculosis, influenza virus and dermatophyte.
Sealwort,For the dry rhizome of liliaceous plant P. kingianum, sealwort or David's-harp.Nature and flavor:It is sweet;It is flat.Return through:The spleen channel;Lung channel;Kidney channel.Effect:Yin nourishing and lung moistening;Invigorate the spleen and benefit qi, Zishen fill fine.There is Yin nourishing and lung moistening;Invigorate the spleen and benefit qi, effect of Zishen fill fine.Often match somebody with somebody ganmai dazao decoction, children's hyperkinetic syndrome, neurosis are controlled in the soft liver nourishing heart of Chinese herbaceous peony.With supplementing qi and nourishing yins such as the Radix Astragali, oyster, the roots of three-nerved spicebush, purging intense heat is purged heat, and controls hyperthyroidism.With hawthorn, matrimony vine, the fruit of glossy privet, the red sage root is controlled in metabolism and disease.And prevent and treat artery sclerosis, anti-aging.Cure mainly:Deficiency of Yin labor is coughed;Xeropulmonary cough;It is insufficiency of the spleen weak;Few dry of food;Quench one's thirst;Deficiency of the kidney soreness and weakness of waist and knees;Impotence and seminal emission;Tinnitus mesh is dark;Poliosis;Body void is won thin;Wind favus disease.Effect:Sealwort has hypotensive, hypoglycemic, reducing blood lipid, and atherosclerosis, the effect such as anti-aging and antibacterial, Siberian solomonseal rhizome polysaccharide has Immunestimulatory effect.For the lung-dryness syndrome due to yin deficiency, the few phlegm of dry cough, and the labor of lung-kidney deficiency coughs chronic cough etc..For weakness of the spleen and the stomach.Both tonifying spleen-yin, and beneficial temper, obtain dizzy for deficiency of kidney essence, soreness and weakness of waist and knees, poliosis and quench one's thirst.
The root of three-nerved spicebush,Flavor efficacy:Ye Xin, it is warm in nature.Warming spleen and stomach for dispelling cold, regulating qi-flowing for relieving pain.Clinical practice:Closely it is used for tumor in digestive tract, such asCancer of the stomach, intestinal cancer, be additionally operable to carcinoma of urinary bladder etc..Additionally, being additionally operable toTreatmentHeart peratodynia, vomiting and diarrhoeaStomachache、Dysmenorrhoea, colic, frequent micturition, rheumatalgia pain, injuries from falls as well and traumatism and bleeding.
Fiveleaf akebia fruit,ForLardizabalaceaePlantAkebi threeleaf akebiaOrAkebia trifoliata varaustralisDry mature fruit.It is sweet, cold in nature, function isDispersing stagnated hepatoqi, promoting blood circulation and stopping pain, relieving restlessness diuresis.Cure mainlyStomachache due to emotional depression and the hyperactive liver-qi attacking the stomach、Stomach energyFood is slow-witted, polydipsia,Dysentery、Pain in the back、Hypochondriac pain, hernia etc..The less single of fiveleaf akebia fruit is used for kinds of tumors with his medicine phases 5 more with controlling in tumour, and has preferable curative effect more.
Rhizoma cyperi,For the dry tuber of Cyperaceae herbaceous plant nutgrass flatsedge for many years.Nature and flavor:It is pungent, slight bitter, flat.Return through:Enter liver, tri-jiao channel.Function:Regulate the flow of vital energy Xie Yu, menstruation regulating, pain relieving.Cure mainly:The diseases such as liver-stomach disharmony, depression of QI, fullness and oppression of chest and abdomen, irregular menstruation, dysmenorrhoea.Main component:Containing volatile oil, wherein predominantly rhizoma cyperi is dilute, cyperol, and fatty acids etc..Effect and effect:Regulate the flow of vital energy Xie Yu, menstruction regulating and pain relieving.Its pharmacological research must be also not enough.Modern experimental tentatively finds have:Analgesic activity.The ethanol extract of rhizoma cyperi can significantly increase animal used as test(Small white mouse)The threshold of pain.Clinical practice:Front people's this product is called " Directorate-General DG of gas disease, the chief commander of female section ", and the pain being widely used in caused by the obstruction of the circulation of vital energy such as belongs to costalgia caused by liver depression(It is more common in chronic hepatitis), such as gastral cavilty gas pain has acid regurgitation vomiting concurrently, eructation and poor appetite, additionally, hypochondriac pain caused by the hot season is wet, or cough or do not cough, without cold but hectic fever, can be strongly fragrant with the promoting the circulation of qi such as the inular flower livering that relaxes, diseases caused by external factors and the person that has stagnation of liver qi concurrently, can with rhizoma cyperi,Perilla leafDeng the strongly fragrant pain relieving of sweating solution, such as fragrant Soviet Union's drink.Especially gynecological diseases and irregular menstruation, witness has stagnation of QI due to depression of the liver, with psychoneural factor(Such as it is in a very depressed state or irascible, nervous)Relevant menstrual pain is preferably.
Aloe,Nature and flavorEffect:Bitter, it is cold in nature.Heat-clearing, defaecation;Desinsection.It is clinicalUsing:Aloe is usually used in gastroenteric tumorTreatment, such as liver cancer, cancer of pancreas.Additionally, be additionally operable to treat Liver Channel real heat dizziness, headache, tinnitus, agitation,Constipation, pediatric epilepsy scared, infantile malnutrition due to digestive disturbances or intestinalparasites.Carious tooth, furuncle carbuncle swells knurl, burn and scald, wet tinea are controlled in leaf external application.
Phoenix-tail fern,Containing flavonoids, sterol, ammonia its acid, lactone, phenols and tannin.The property of medicine is bitter, cold.Return liver, stomach, lung, large intestine, bladder warp.Drug effect internal heat anticance, removing damp-heat, cooling blood and hemostasis.It is medicinal:(1)Internal heat anticance, for carcinoma product poison:Cancer of the stomach, the carcinoma of the rectum, lung cancer etc.;(2)The heat that disappears dehumidifying, for damp and hot inflammation:Oxyhepatitis etc.;(3)Cooling blood and hemostasis, for blood-head bleeding:Blood-head hematuria etc..
Tomato,Tomato has fat-reducing Weight reducing , dispelling fatigue, improve a poor appetite, improve the digestion to protein, reduce gasteremphraxis dyspepsia the effects such as.In recent years, in the anti-cancer or health food that numerous worldwide organizations are recommended, tomato always ranks among the best.Find in substantial amounts of epidemiological survey and zoopery, outstanding representation of the tomato in cancer-resisting is mostly derived from lycopene therein.So, lycopene be how to give protection against cancer, the first of anticancer, by a series of biochemical action, lycopene can promote Carcinoma cell differentiation (to good direction conversion), inhibition cancer cell propagation.Second, immune function of human body can be strengthened.Lycopene can promote some to have the cytokine secretion of anti-cancer, antitumaous effect, such as interleukins-II, dissolution of the activated lymphocyte to cancer cell;The lymphocyte being activated can discharge cytokine such as TNF etc. again, have lethal effect to tumour cell.3rd, lycopene has stronger It is anti-oxidant Effect.The aging of cell, damage are all relevant with Free Radical with canceration, and antioxidant (such as lycopene) is effectively removing free radical, so as to play whole body health-care effect, wherein be just included in protective effect on cancer risk playing an important role.
The effect of the present invention:
Cure mainly:Cancer of the stomach, especially because a variety of causes cannot carry out the late gastric cancer of Surgery for Gastric Carcinoma, with very low cost, fundamentally improves physical function, and control tumour continues to overgrow and makes it that final disappearance is gradually reduced, so as to recover healthy.
It is simultaneous to control:The cancer in digestive system such as throat cancer, the cancer of the esophagus, cardiac cancer, pylorus cancer, colorectal cancer.
Our the characteristics of is:
1st, flavour of a drug are more, and dosage is moderate, do not waste.
2nd, selected flavour of a drug are mostly that proved by modern medicine pharmacological evaluation can be for cancer, and existing proved recipe for cancer, then always there are medicines more than half to be all not proved function for cancer and effect by modern medicine pharmacological evaluation in folk prescription.
3rd, for focus, arrow arrow punching, i.e., selected flavour of a drug all especially grow tender of and hit the bull's eye, and As the medicine took effect, the symptoms lessened.As long as rather than it is for cancer, just jump on the bandwagon, being as a result that " dragon " is more bad on the contrary harnesses the river.
4th, as much as possible " neutralisation ", i.e., selected flavour of a drug generally keep " neutrality ", do not tremble with fear not dry, not hot not cool.Patient can be thus set to suffer less within the cycle of whole medication, pull the devil by the tail less.And if really there is the situation of " getting angry " or " under let out ", then can be directed to concrete individual concrete condition completely, add a bit " stopping leak ", the medicine of " fall fire " dialectically temporarily and specifically solve.Rather than imagine at the very start patient may on tell or drop, and some unnecessary medicines are added to prescription, patient is all taken always during very long very long medication, ultimately cause adverse consequences.
Specific embodiment:Radix Astragali 20g, salvia chinensis 9g, marine alga 15g, sealwort 15g, fiveleaf akebia fruit 20g, aloe 20g, phoenix-tail fern 20g are respectively amplified into 10 times, after clean water, it is placed in BT-2 stainless steels to extract in kettle, plus after 7-9 times of running water, it is heated to 100 DEG C of constant temperature to extract 1 hour or so, extraction fluid, pressure filtration, filtrate is standby.Extract for second:Add in kettle the 5-7 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract or so half an hour, extraction fluid, pressure filtration, filtrate is standby.Third time is extracted:Add in kettle the 3-5 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract 20 minutes or so, extraction fluid, pressure filtration, filtrate is standby.Concentration:The extract of three times is merged, is placed in B-500 type triple effect vacuum high energy evaporation concentrators, reduced pressure (negative 200mmHg), be heated to 80 DEG C, be concentrated into relative density 1.10~1.20, it is standby.Powder processed:Radix Codonopsis 9g, rhizoma cyperi 7g, root of three-nerved spicebush 3g are respectively amplified into 10 times, it is end together to crush, cross 80 mesh sieves, it is standby.Dispensing:In 300,000 grades of dust proof workshops, medicinal powder is put in mixer together with aforementioned concentrate and is sufficiently mixed, stir.Drying, crushing:The spice being well mixed is placed in into 60-70 DEG C of baking 4-5 hour in baking oven, is then crushed, cross 100 mesh sieves.Granulation:The spice being well mixed is inserted in comminutor and is granulated.Whole grain:The particle for making is carried out into whole grain, 35 mesh sieves are crossed.It is dried:Whole good particle is inserted in heat circulation drying oven, aeration-drying is to moisture < 8% at 80 DEG C.Packaging:First pack, the particle by made by is fitted into polyethylene plastic bag, every bag of 8g.Then the pouch mounted box for installing, vanning, sterilizing (are adopted into 60Co irradiation, irradiation dose is 8kGy).Finally, irradiated finished product is put in storage by the principle of first in first out.
Claims (2)
1. the attached letter cancer of the stomach of Hui ethnic group's Chinese medicine disappears particle and preparation method thereof, it is characterised in that it is by made by the raw material of following weight proportion:
Radix Astragali 20g, Radix Codonopsis 9g, salvia chinensis 9g, marine alga 15g
Sealwort 15g, root of three-nerved spicebush 3g, fiveleaf akebia fruit 20g, rhizoma cyperi 7g,
Aloe 20g, phoenix-tail fern 20g, tomato 50g
This side is substantially square for one decoction on the one;In practical application, also 1-3 tastes " dialectical compatibility " medicine can be increased according to the physique of patient and conditions.
2. the attached letter cancer of the stomach of Hui ethnic group's Chinese medicine according to claim 1 disappears the weight proportion of particle, it is characterised in that including following preparation processes:
The preparation of A, extract
(1), extract
A, for the first time extraction:By the weight of said herbal medicine in addition to Radix Codonopsis, the root of three-nerved spicebush, rhizoma cyperi, tomato, all amplify 10 times, after clean water, it is placed in BT-2 stainless steels to extract in kettle, plus after 7-9 times of running water, is heated to 100 DEG C of constant temperature and extracts 1 hour or so, extraction fluid, pressure filtration, filtrate is standby;
B, second extraction:Add in kettle the 5-7 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract or so half an hour, extraction fluid, pressure filtration, filtrate is standby;
C, third time are extracted:Add in kettle the 3-5 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract 20 minutes or so, extraction fluid, pressure filtration, filtrate is standby;
(2), concentration
The extract of three times is merged, is placed in B-500 type triple effect vacuum high energy evaporation concentrators, reduced pressure (negative 200mmHg), be heated to 80 DEG C, be concentrated into relative density 1.10~1.20, it is standby;
(3), powder processed
Radix Codonopsis 9g, root of three-nerved spicebush 3g, rhizoma cyperi 7g are amplified into 10 times, it is end together to crush, cross 80 mesh sieves, it is standby;
(4), dispensing
In 300,000 grades of dust proof workshops, medicinal powder is put in mixer together with aforementioned concentrate and is sufficiently mixed, stir;
(5), drying, crushing
The spice being well mixed is placed in into 60-70 DEG C of baking 4-5 hour in baking oven, is then crushed, cross 100 mesh sieves;
(6), granulate
The spice being well mixed is inserted in comminutor and is granulated;
(7), whole grain
The particle for making is carried out into whole grain, 35 mesh sieves are crossed;
(8), it is dried
Whole good particle is inserted in heat circulation drying oven, aeration-drying is to moisture < 8% at 80 DEG C;
B, packaging
First pack, the pill by made by is fitted into polyethylene plastic bag, every bag of 8g;Then the pouch mounted box for installing, vanning, sterilizing (are adopted into 60Co irradiation, irradiation dose is 8kGy);
C, warehouse-in
Irradiated finished product is put in storage by the principle of first in first out.
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2015
- 2015-11-08 CN CN201510750411.7A patent/CN106668500A/en not_active Withdrawn
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