CN106668400A - Hui-nationality Chinese herbal red ginseng gastric cancer-treating tablet and preparation method thereof - Google Patents

Hui-nationality Chinese herbal red ginseng gastric cancer-treating tablet and preparation method thereof Download PDF

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CN106668400A
CN106668400A CN201510750835.3A CN201510750835A CN106668400A CN 106668400 A CN106668400 A CN 106668400A CN 201510750835 A CN201510750835 A CN 201510750835A CN 106668400 A CN106668400 A CN 106668400A
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cancer
medicine
red ginseng
extract
treating
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王学礼
王桂芳
赵萍
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Yinchuan Shanghetu New Technology Development Co Ltd
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Yinchuan Shanghetu New Technology Development Co Ltd
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Abstract

The invention discloses a formula of a Hui-nationality Chinese herbal red ginseng gastric cancer-treating tablet and a preparation method thereof. The medicine is a green high-tech Chinese herbal medicine for treating late gastric cancer, especially late gastric cancer which cannot be operated due to various reasons. The preparation method comprises the following steps: mixing Chinese herbal medicines such as ficus carica, solanum lyratum thumb, Chinese lobelia, radix actinidiae, turmeric, fiveleaf akebia fruit, etc. according to a certain ratio, adding water and decocting, extracting, concentrating and tabletting to obtain a traditional Chinese medicine tablet, which is used for mainly treating gastric cancer as well as treating digestive cancers such as pharyngolaryngeal cancer, esophagus cancer, cardiac carcinoma, colorectal cancer, etc. The invention has the characteristics of less medicinal odour and moderate dosage. The selected medicines are proved through pharmacology experiments of modern medicine to be capable of treating cancers.

Description

Hui ethnic group's Chinese medicine red ginseng cancer of the stomach disappears piece and preparation method thereof
Technical field
Hui ethnic group's Chinese medicine red ginseng cancer of the stomach according to the present invention piece that disappears is a kind of to treat late gastric cancer especially because the green high-tech Chinese herbal medicine of late gastric cancer that cannot be performed the operation of a variety of causes.The invention further relates to the preparation method of the medicine, belongs to traditional Chinese medicine class.
Background technology
According to《China's tumour registration annual report in 2014》Data display, according to China for each person 74 years old life-span calculate, Chinese all one's life suffer from malignant tumour probability be 22%, average minute clock has 6 people to be diagnosed as malignant tumour, and tumour has become a kind of common disease in China.At present the cancer patient of China is about ten thousand people more than 700, and every year with the speed of more than 100 ten thousand people in increase.And the whole world
According to statistics, in the cancer patient of China nearly 8,000,000, have 31.27% for Alimentary System patient, wherein patients with gastric cancer accounts for the 41.83% of Alimentary System patient, almost half.
China is one of incidence gastric cancer rate highest country, and the whole world is annual newly to send out patients with gastric cancer more than 100 ten thousand, and China just account for 42%, and death toll China has accounted for 35%, and the M & M of Chinese cancer of the stomach is world average level more than 2 times!Inherent cause among these, immune factor, helicobacter pylori infections factor are all nothing difficult, and most anxious is then environment and dietary factor ...
The early symptom of cancer of the stomach is not obvious, generally needs time of 2 years or so from incidence gastric cancer to finding tumour, therefore often ignored, once and to standing, most likely reach an advanced stage.
It is operation to control cancer of the stomach the best way at present, postoperative to be also performed to chemotherapy, and chemotherapy not only large side effects, patient suffering is difficult to stand, and success rate is also very low, 1 year life cycle after most Chemotherapy in Patients less than --- certainly this is also relevant with the over-treatment given birth to without skilful doctor.And on the other hand, although some are detected to be cancer of the stomach, because a variety of causes cannot be performed the operation, can only palliative treatment, expect coming for miracle ...
Cancer of the stomach is at present more refractory disease more, but refractory representative cannot be controlled, and in addition to above-mentioned western medical treatment method, the traditional Chinese medical science also has many effectively treatment methods.The traditional Chinese medical science, according to the whole body feature diagnosis and treatment of patient, goes for various each phase cancer with organic conception.The advantage of Chinese medicine cancer is to be conducive to stablizing the state of an illness, and toxic and side effect is slight, symptom improves more apparent, slows down PD, tumor regression or the longer-term existence of band knurl, and patient is easy to receive and expense is than less expensive.At present doctor trained in Western medicine is also considered as traditional Chinese medicine can contribute to reducing the toxicity of Radiotherapy chemotherapy as the auxiliary treatment of cancer, improve cancer related symptoms, improve life quality, extend life cycle.But exist problem be the traditional Chinese medical science prescription uniformity it is poor, treatment mainly be experience.From in terms of existing proved recipe for cancer, folk prescription, always there is --- majority is more than more than half --- medicine to be all not prove " compatibility " medicine of function for cancer and effect " diagnosis and treatment based on an overall analysis of the illness and the patient's condition " by modern medicine pharmacological evaluation in selected Chinese herbal medicine medicinal material, inventors believe that very improper;And folk prescription, folk prescription cure the disease lean on be test, often stop over the time cured the disease.
The content of the invention
The purpose of the present invention, be aiming at Cancer in China patient assessment be difficult to and in the side's of curing the desease poor consistency, repeatable poor, high level evidence-based medicine EBM be theoretical and the relative shortage of evidence, thus the situation for waiting deficiency by rule of thumb that is mainly for cancer, propose a kind of new dosage and preparation method, there is provided a kind of from the beginning of prevention, the incidence of disease of cancer of the stomach is reduced, starts to slow down its tempo from canceration, the green high-tech Chinese herbal medicine for inducing its atrophy apoptosis is started from tumour.Specifically, the present invention one be particularly suited for use in treatment cancer before larger gastric ulcer in case its canceration, two is the especially big gastric ulcer that can treat the cancer of the stomach initial stage, in case it continues to deteriorate, three are can induce into the cancerous swelling atrophy apoptosis of knurl, with very low cost, fundamentally improve physical function, so as to get well.Its sharpest edges are to greatest extent to induce self apoptosis of cancer cell and differentiation, promote cancerous swelling progressively atrophy.In specific formula, also coordinate diagnosis and treatment based on an overall analysis of the illness and the patient's condition, according to the origin cause of formation of cancer of the stomach because dietary factor makes nutrient disequilibrium cause immunologic hypofunction, because Helicobacter pylori infection causes stomach normal cell to be compromised, apoptosis, gastritis, digestive tract ulcer, lymphoproliferative gastric lymphoma " is taken advantage of a weak point " evil poison positive pressure, flee channels and collaterals visitor the characteristics of internal organs form long product and cause the basic pathology interpretation of the cause, onset and process of an illness such as Metastasis of Gastric Cancer because evil poison being tied in sick protracted blood stasis and being wrapped hemostasis and is taken advantage of a weak point in opponent's defence, with the tonifying speen and tonifying kidney strengthening vital QI to eliminate pathogenic factors method that tonification and purgation in combination, it is empty in healthy tendency to correct, poly- and internal organs imbalance of yin and yang function reduction the deficiency of the solidifying poison of heresy, adjust and improve the immunologic function of body.Simultaneously according to the concrete condition of patient, different formulas, or easypro liver and stomach, drop check pain, or detoxification and removing stasis, clearing heat and nourishing yin, or warming spleen and stomach for dispelling cold, strengthening the spleen and stomach, or strongly invigorating QI and blood are respectively adopted, strengthening spleen, tonifying kidney ... is reachingTonification and purgation in combination, reinforcing and reducing methods and use, the purpose of overall tumor suppression, so as to improve the overall curative effect and late result of curing gastric cancer, a kind of green high-tech Chinese herbal medicine formula and compound method that function for cancer and effect are proved by modern medicine pharmacological evaluation is provided for patients with gastric cancer, with very low or relatively low cost, fundamentally improve physical function, the deterioration of symptom management simultaneously makes the state of an illness gradually take a turn for the better, and finally recovers healthy.Thus also to patient one select different treatment methods or several method to share particularly traditional Chinese and western medicine to combine the leeway of complex treatment application to consider according to the personal state of an illness, economic situation, personal inclination, to obtaining optimum curative effect, survival rate is easily improved --- particularly more than 5 years survival rates.
Technical scheme proposed by the invention is:
First, Hui ethnic group's Chinese medicine " red ginseng cancer of the stomach disappear piece " of described treatment cancer of the stomach and preparation method thereof, is by made by following weight proportion raw material:
Red ginseng 9g, bittersweet 20g, rhizoma arisaematis 7g, hawthorn 15g,
Peach kernel 9g, rhizoma cyperi 7g, sweet root 7g, salvia chinensis 20g,
Tuber of pinellia 3g, tomato 50g(Or it is appropriate)
This side is substantially square for one decoction on the one.In practical application, also 1-3 tastes " dialectical compatibility " medicine can be increased according to the physique of patient and conditions.
In view of with this, basic side's decoction decoction of medicinal ingredients amount is big, taste is not good enough, patient is difficult to drink, therefore must be prepared using special process.
2nd, it is by the preparation method that above-mentioned each raw material makes Chinese medicinal tablet of the present invention:
A, extract preparation
(1), extract
A, for the first time extraction:By the weight of said herbal medicine in addition to red ginseng, the tuber of pinellia, tomato, all amplify 10 times, after clean water, it is placed in BT-2 stainless steels to extract in kettle, plus after 7-9 times of running water, is heated to 100 DEG C of constant temperature and extracts 1 hour or so, extraction fluid, pressure filtration, filtrate is standby.
B, second extraction:Add in kettle the 5-7 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract or so half an hour, extraction fluid, pressure filtration, filtrate is standby.
C, third time are extracted:Add in kettle the 3-5 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract 20 minutes or so, extraction fluid, pressure filtration, filtrate is standby.
(2), concentration
The extract of three times is merged, is placed in B-500 type triple effect vacuum high energy evaporation concentrators, reduced pressure (negative 200mmHg), be heated to 80 DEG C, be concentrated into relative density 1.10~1.20, it is standby.
(3), powder processed
Red ginseng 9g, tuber of pinellia 3g are amplified into 10 times, it is end together to crush, cross 80 mesh sieves, it is standby.
(4), dispensing
In 300,000 grades of dust proof workshops, medicinal powder is put in mixer together with aforementioned concentrate and is sufficiently mixed, stir.
(5), drying, crushing
The spice being well mixed is placed in into 60-70 DEG C of baking 4-5 hour in baking oven, is then crushed, cross 100 mesh sieves.
(6), granulate
The spice being well mixed is inserted in comminutor and is granulated.
(7), whole grain
The particle for making is carried out into whole grain, 35 mesh sieves are crossed.
(8), it is dried
Whole good particle is inserted in heat circulation drying oven, aeration-drying is to moisture < 8% at 80 DEG C.
(9) compressing tablet
Add magnesium stearate to be well mixed dry mixed gained medicine and be placed in compressing tablet in tablet press machine(Also can coating), every 0.5g.
B, packaging
During tablet is fitted into vial or vinyon bottle, then the bottle mounted box for installing, vanning, sterilizing (are adopted into 60Co irradiation, irradiation dose is 8kGy).
C, warehouse-in
Irradiated finished product is put in storage by the principle of first in first out.
Routine instructions of taking of the invention:Above-mentioned tablet three times a day, each 10-12 pieces, on an empty stomach (taking half an hour after can not drink water in a large number, in order to avoid water down liquid).The pungent grade food larger to gastrointestinal irritation is not eaten during medication.This medicine is a course for the treatment of in three months, typically takes two to three courses for the treatment of, at most takes four courses for the treatment of.
This medicine does medicine efficacy enhancing ingredient and takes better with pan-fried tomato soup.The specific practice of pan-fried tomato soup is:Take from so well-done little tomato(50 grams or so)Chopping, puts 10 grams or so vegetable oil in pot, heat, and is put into appropriate chopped spring onion, salt, pours into be decocted in pot by the tomato of chopping when chopped spring onion blows out fragrance and fries 1-2 minutes, then infuses to be got away into suitable quantity of water and take the dish out of the pot.The pungent grade food larger to gastrointestinal irritation is not eaten during medication.
The effect of each raw material of the present invention:
Red ginseng,Red ginseng is called round ginseng, is dry root of the cultivation product of Araliaceae ginseng Jing after steaming.Nature and flavor:Sweet, slight bitter, temperature.Return through:Returns spleen, lung, the heart channel of Hang-Shaoyin.Effect:Reinforce vital energy, veins takes off admittedly, nourishing qi to stop.Cure mainly:It is intended to take off for body void, cold weak pulse of limb is Qi dysfunction in blood control, metrostaxis;Heart failure, cardiogenic shock.The effect of red ginseng be tonifying Qi, enriching yin, beneficial blood, promote the production of body fluid, cardiac stimulant, stomach invigorating, calmness, control body void be intended to take off, cold weak pulse of limb, Qi dysfunction in blood control, metrostaxis, heart failure, cardiogenic shock, these effect red ginsengs do not have strict difference with white ginseng, but it is generally acknowledged that red ginseng is better than white ginseng in terms of qi-restoratives.Long term usage red ginseng can improve body immunity, antifatigue, radioresistance, suppress tumour, adjustment human endocrine system.Red ginseng is suitable for old man, weakness due to chronic disease person, and red ginseng has the strong feature of big fire, strength foot, effect, the first-selected tonic of the person that is overabundant YIN leading to insufficient YANG, pharmaceutically treatment collapse or mends multiplex red ginseng by force.Red ginseng can reinforce vital energy, Gu de- promote the production of body fluid, calm the nerves.It is deficient that red ginseng controls internal lesion caused by overexertion, deficiency of food, burnout, and food is told in gastric disorder causing nausea, and lingering diarrhea of defecating, empty cough and asthma promotees, and spontaneous perspiration takes off cruelly, palpitates with fear, and forgetful, dizziness and headache, impotence, frequent micturition is quenched one's thirst, and woman uterine bleeding, children shy slowly, and multiple, the card of all qi-blood-body fluid deficiencies empty long.
Bittersweet,Indication:It is clearing heat and detoxicating, inducing diuresis and reducing edema, anticancer.Herb:For catching a coldHeating, breastCarbuncleDislike sore,Jaundice with damp-heat pathogenAscites,Leukorrhea,Nephritic dropsy, external application controls carbuncleFurunclePoison.Root:Arthralgia due to wind-dampness, there is anti-TumourEffect, and to golden yellowColorStaphylococcus,Pseudomonas aeruginosaThere is obvious bacteriostasis.
Rhizoma arisaematis,Nature and flavorEffect:It is bitter, pungent, it is warm in nature, it is poisonous.It is eliminating dampness and eliminating phlegm, eliminating the phlegm arresting convulsion, dispersing swelling and dissipating binds.It is clinicalUsing:Suitable for kinds of tumors, such as tumor in digestive tract, intracranial tumour, brain metastasis, or tumor lympha is carried down shifting, sonCervical carcinomaOral cavityTumour,NerveSystem tumor.Additionally it is applied to heap soil or fertilizer over and around the roots of apoplexy phlegm, facial paralysis, hemiplegia, insane chronic, infantile convulsion, lockjaw, anemophlegmatic vertigo, larynx numbness, scrofula tuberculosis, carbuncle swells, traumatic injury, snake bite and insect sting etc..
Hawthorn,Contain flavones in fruit, ursolic acid, oxalic acid, citric acid, tartaric acid, butanedioic acid, vitamin C etc., nature and flavor are sour, sweet, tepor, returns spleen, stomach, Liver Channel, digestion gathered food, the stagnant stasis of blood of change, indication eating accumulation, abdominal distention, dysentery, dysmenorrhea due to blood stasis, Amenorrhea, postpartum abdominal pain, lochiorrhagia, hernia or testiclar gall, hyperlipidemia;The experiment proved that, with more lasting hypotensive effect, can strengthen coronary flow, reduce myocardial oxygen consumption has protective effect to myocardial ischemia, anoxic, the effect such as also anti-ventricular fibrillation, auricular fibrillation and paroxysmal arrhythmia cordis;Additionally, hawthorn also has promotes the effect such as digestion, anti-oxidant, enhancing immunologic function, antibacterial action, protective effect on cancer risk, contraction uterus, promotion uterine involution, pain relieving.
Peach kernel,Meridian distribution of property and flavor】:Bitter, sweet, flat.The thoughts of returning home, liver, large intestine channel.Effect of peach kernel and effect:Promoting blood circulation, relaxes bowel, relieving cough and asthma.For Amenorrhea,Dysmenorrhoea, wei lump in the abdomen lump in the abdomens, injury from falling down, intestinal drynessConstipation
The main component of peach kernel:Containing amygdalin (Amygdalin), emulsin (Emulsin), allantoinase (Allantoinase), lactase (Lactase), vitamin B1. volatile oil, fat oil, mainly containing olein and a small amount of glyceryl linoleate in oil. emulsin includes amygdalase (Amygdalase) and prunase (Prunase). the amygdalin in peach kernel produces hydrogen cyanide, benzaldehyde and glucose as the amygdalin in almond, Jing after enzyme or sour water solution.Effect:1. dissolving stasis blood effect, 2. antiinflammatory action, 3. resistsAllergyEffect, 4. other effects:Bitter no benevolence glucoside, there is antitussive effect.Fat oil in peach kernel(Almond oil)There is anthelmintic action, be 80.8% to the anthelminthic effect of pinworm, be 70% to roundworm effect.
Rhizoma cyperi,For the dry tuber of Cyperaceae herbaceous plant nutgrass flatsedge for many years.Nature and flavor:It is pungent, slight bitter, flat.Return through:Enter liver, tri-jiao channel.Function:Regulate the flow of vital energy Xie Yu, menstruation regulating, pain relieving.Cure mainly:The diseases such as liver-stomach disharmony, depression of QI, fullness and oppression of chest and abdomen, irregular menstruation, dysmenorrhoea.Main component:Containing volatile oil, wherein predominantly rhizoma cyperi is dilute, cyperol, and fatty acids etc..Effect and effect:Regulate the flow of vital energy Xie Yu, menstruction regulating and pain relieving.Its pharmacological research must be also not enough.Modern experimental tentatively finds have:Analgesic activity.The ethanol extract of rhizoma cyperi can significantly increase animal used as test(Small white mouse)The threshold of pain.Clinical practice:Front people's this product is called " Directorate-General DG of gas disease, the chief commander of female section ", and the pain being widely used in caused by the obstruction of the circulation of vital energy such as belongs to costalgia caused by liver depression(It is more common in chronic hepatitis), such as gastral cavilty gas pain has acid regurgitation vomiting concurrently, eructation and poor appetite, additionally, hypochondriac pain caused by the hot season is wet, or cough or do not cough, without cold but hectic fever, can be strongly fragrant with the promoting the circulation of qi such as the inular flower livering that relaxes, diseases caused by external factors and the person that has stagnation of liver qi concurrently, can with rhizoma cyperi,Perilla leafDeng the strongly fragrant pain relieving of sweating solution, such as fragrant Soviet Union's drink.Especially gynecological diseases and irregular menstruation, witness has stagnation of QI due to depression of the liver, with psychoneural factor(Such as it is in a very depressed state or irascible, nervous)Relevant menstrual pain is preferably.
Sweet root,Root and root system master contain triterpenoid saponin, wherein main one kind is commonly called as glycyrrhizin, and the 4',7-Dihydroxyflavanone of chlorins compound containing flavones, liquiritin etc., the also Radix Glycyrrhizae of compound containing Coumarins coumarin, glycyol etc., separately containing compounds such as alkaloid, Radix Glycyrrhizae glucan GBW.Sweet, mild-natured, returns spleen, stomach, the heart, lung channel, invigorating middle warmer and replenishing QI, relieving spasm to stop pain moistens the lung and relieve the cough, purging intense heat and detonicating, coordinating the drug actions of a prescription.Burnout deficiency of food is cured mainly, the thin face of flesh is yellow, palpitation, suffer from abdominal pain loose stool, four limbs contraction, hysteria, cough and asthma, abscess of throat, ulcerative carbuncle pyogenic infections, infant fetal toxin and medicine, food poisoning.Radix Glycyrrhizae has removing toxic substances antibacterial action, anti-AIDS toxic action, licorice polysaccharide has obvious inhibiting effect to vesicular stomatitis virus, adenovirus II type, herpes simplex virus I type and vaccinia virus in vitro, not only can directly inactivate this several virus, and also have effect to intracellular virus, additionally, Radix Glycyrrhizae also has Antitussive and Expectorant Effect, with anti-inflammatory, affect digestive system, immune system and cardiovascular system, the effect such as antitumor and anti-mutation, corticotropin sample, anti-oxidant.The acute and chronic viral hepatitis of clinical treatment, treatment diabetes, treatment gastric and duodenal ulcer etc..The present invention is to the concocting method of Radix Glycyrrhizae:Extracting liquorice, except removing LU and impurity, size bar is separate, be dipped to 3 four one-tenth it is saturating when, pick up and soften, cut sheet, be dried.
Salvia chinensis,For the herb of Labiatae annual herb plant salvia chinensis, flavor efficacy:It is bitter, mild-natured.It is clearing heat and detoxicating, cool blood flat liver, inducing diuresis for removing edema, dissipating bind.Clinical practice:It is usually used in treating the cancer of the esophagus, carcinoma of parotid gland, liver cancer, cancer of the stomach, cardia cancer etc..Medical science religion ' educate net compile additionally, be additionally operable to treat virus hepatitis, hot summer weather rush down dysentery, infantile acute nephritis, oedema, rheumatic arthritis, chyluria, treating swelling and pain by traumatic injury, venomous snake bite, boil swell and ache, metrorrhagia etc..
The tuber of pinellia,Nature and flavor:Taste is pungent;It is warm in nature;It is poisonous.Return through:The spleen channel;Stomach;Lung channel.Effect:It is eliminating dampness and eliminating phlegm;Stopping nausea and vomiting by lowering the adverse flow of QI;Dissolving lump and resolving mass.Cure mainly:Cough and phlegm;Vomiting gastric disorder causing nausea;Feeling of oppression and fullness in the chest and epigastrium dizziness of having a headache;Uneasy sleeping at night;Gall subcutaneous nodule;Swollen ulcer drug.Effect:Dried pinellia:Crude drug is taken, impurity is removed, cleaning, drying, the used time smashs to pieces.It is poisonous, many external applications, based on swelling and pain relieving.Rhizoma pinellinae praeparata:It is longer than eliminating dampness, and warm nature is low.The lime tuber of pinellia, for abundant expectoration cough and asthma, phlegm retention anti-dazzle nervous, anemophlegmatic vertigo, phlegm and headache.Control based on cold phlegm, damp phlegm, while with the effect for adjusting spleen and stomach.Prepared RHIZOMA PINELLIZE without adju-vant:It is longer than resolving sputum.Alum soaks or boils or pickle.The side effect of pungent thorn larynx is eliminated, toxicity is reduced, based on eliminating dampness and eliminating phlegm.Function cures mainly eliminating dampness and eliminating phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.Wet phlegm and cold drink is controlled, is vomitted, gastric disorder causing nausea, cough and phlegm, fullness in chest, phlegm and headache, dizziness and sleepless.Outer subduing inflammation.Pinellia:It is longer than stopping nausea and vomiting by lowering the adverse flow of QI.Ginger alum boils or pickles or steam, or ginger is fried.Middle benefit gas resolving sputum, based on stopping nausea and vomiting by lowering the adverse flow of QI.Function with cure mainly:Stopping nausea and vomiting by lowering the adverse flow of QI.For vomiting gastric disorder causing nausea, chest gastral cavity ruffian, globus hysteriocus.Rhizoma Pinelliae Fermentata:It is longer than and eliminates indigestion and phlegm.Levigation is dried in dried pinellia immersion, and ginger juice, flour are mixed well, and fermentation is made.Dampness elimination invigorating the spleen, help digestion antidiarrheal.The bamboo juice tuber of pinellia:The tuber of pinellia or rhizoma pinellinae praeparata, bamboo juice is mixed and dried in the shade.Temperate-dryness subtract greatly, are suitable to gastropyretic vomiting, and lung heat yellow and sticky sputum closes aphasia from apoplexy in phlegm heat.
Tomato,Tomato has fat-reducing Weight reducing , dispelling fatigue, improve a poor appetite, improve the digestion to protein, reduce gasteremphraxis dyspepsia the effects such as.In recent years, in the anti-cancer or health food that numerous worldwide organizations are recommended, tomato always ranks among the best.Find in substantial amounts of epidemiological survey and zoopery, outstanding representation of the tomato in cancer-resisting is mostly derived from lycopene therein.So, lycopene be how to give protection against cancer, the first of anticancer, by a series of biochemical action, lycopene can promote Carcinoma cell differentiation (to good direction conversion), inhibition cancer cell propagation.Second, immune function of human body can be strengthened.Lycopene can promote some to have the cytokine secretion of anti-cancer, antitumaous effect, such as interleukins-II, dissolution of the activated lymphocyte to cancer cell;The lymphocyte being activated can discharge cytokine such as TNF etc. again, have lethal effect to tumour cell.3rd, lycopene has stronger It is anti-oxidant Effect.The aging of cell, damage are all relevant with Free Radical with canceration, and antioxidant (such as lycopene) is effectively removing free radical, so as to play whole body health-care effect, wherein be just included in protective effect on cancer risk playing an important role.
The effect of the present invention:
Cure mainly:Cancer of the stomach, especially because a variety of causes cannot carry out the late gastric cancer of Surgery for Gastric Carcinoma, with very low cost, fundamentally improves physical function, and control tumour continues to overgrow and makes it that final disappearance is gradually reduced, so as to recover healthy.
It is simultaneous to control:The cancer in digestive system such as throat cancer, the cancer of the esophagus, cardiac cancer, pylorus cancer, colorectal cancer.
Our the characteristics of is:
1st, flavour of a drug are more, and dosage is moderate, do not waste.
2nd, selected flavour of a drug are mostly that proved by modern medicine pharmacological evaluation can be for cancer, and existing proved recipe for cancer, then always there are medicines more than half to be all not proved function for cancer and effect by modern medicine pharmacological evaluation in folk prescription.
3rd, for focus, arrow arrow punching, i.e., selected flavour of a drug all especially grow tender of and hit the bull's eye, and As the medicine took effect, the symptoms lessened.As long as rather than it is for cancer, just jump on the bandwagon, being as a result that " dragon " is more bad on the contrary harnesses the river.
4th, as much as possible " neutralisation ", i.e., selected flavour of a drug generally keep " neutrality ", do not tremble with fear not dry, not hot not cool.Patient can be thus set to suffer less within the cycle of whole medication, pull the devil by the tail less.And if really there is the situation of " getting angry " or " under let out ", then can be directed to concrete individual concrete condition completely, add a bit " stopping leak ", the medicine of " fall fire " dialectically temporarily and specifically solve.Rather than imagine at the very start patient may on tell or drop, and some unnecessary medicines are added to prescription, patient is all taken always during very long very long medication, ultimately cause adverse consequences.
Specific embodiment:Bittersweet 20g, rhizoma arisaematis 7g, hawthorn 15g, peach kernel 9g, rhizoma cyperi 7g, sweet root 7g, salvia chinensis 20g are respectively amplified into 10 times, after clean water, it is placed in BT-2 stainless steels to extract in kettle, plus after 7-9 times of running water, it is heated to 100 DEG C of constant temperature to extract 1 hour or so, extraction fluid, pressure filtration, filtrate is standby.Extract for second:Add in kettle the 5-7 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract or so half an hour, extraction fluid, pressure filtration, filtrate is standby.Third time is extracted:Add in kettle the 3-5 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract 20 minutes or so, extraction fluid, pressure filtration, filtrate is standby.Concentration:The extract of three times is merged, is placed in B-500 type triple effect vacuum high energy evaporation concentrators, reduced pressure (negative 200mmHg), be heated to 80 DEG C, be concentrated into relative density 1.10~1.20, it is standby.Powder processed:Red ginseng 9g, tuber of pinellia 3g are respectively amplified 10 times, it is end together to crush, and crosses 80 mesh sieves, standby.Dispensing:In 300,000 grades of dust proof workshops, medicinal powder is put in mixer together with aforementioned concentrate and is sufficiently mixed, stir.Drying, crushing:The spice being well mixed is placed in into 60-70 DEG C of baking 4-5 hour in baking oven, is then crushed, cross 100 mesh sieves.Granulation:The spice being well mixed is inserted in comminutor and is granulated.Whole grain:The particle for making is carried out into whole grain, 35 mesh sieves are crossed.It is dried:Whole good particle is inserted in heat circulation drying oven, aeration-drying is to moisture < 8% at 80 DEG C.Compressing tablet:Add magnesium stearate to be well mixed dry mixed gained medicine and be placed in compressing tablet in tablet press machine(Also can coating), every 0.5g.Packaging:The tablet for pressing is fitted into vinyon bottle, then the bottle mounted box for installing, vanning, sterilizing (are adopted into 60Co irradiation, irradiation dose is 8kGy).Finally, irradiated finished product is put in storage by the principle of first in first out.

Claims (2)

1. Hui ethnic group's Chinese medicine red ginseng cancer of the stomach disappears piece and preparation method thereof, it is characterised in that it is by made by the raw material of following weight proportion:
Red ginseng 9g, bittersweet 20g, rhizoma arisaematis 7g, hawthorn 15g,
Peach kernel 9g, rhizoma cyperi 7g, sweet root 7g, salvia chinensis 20g,
Tuber of pinellia 3g, tomato 50g(Or it is appropriate)
This side is the substantially square of one decoction on the one, in practical application, can also increase 1-3 tastes " dialectical compatibility " medicine according to the physique of patient and conditions.
2. the Hui ethnic group's Chinese medicine red ginseng cancer of the stomach according to claim 1 disappears the weight proportion of piece, it is characterised in that including following preparation processes:
The preparation of A, extract
(1), extract
A, for the first time extraction:By the weight of said herbal medicine in addition to red ginseng, the tuber of pinellia, tomato, all amplify 10 times, after clean water, it is placed in BT-2 stainless steels to extract in kettle, plus after 7-9 times of running water, is heated to 100 DEG C of constant temperature and extracts 1 hour or so, extraction fluid, pressure filtration, filtrate is standby;
B, second extraction:Add in kettle the 5-7 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract or so half an hour, extraction fluid, pressure filtration, filtrate is standby;
C, third time are extracted:Add in kettle the 3-5 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract 20 minutes or so, extraction fluid, pressure filtration, filtrate is standby;
(2), concentration
The extract of three times is merged, is placed in B-500 type triple effect vacuum high energy evaporation concentrators, reduced pressure (negative 200mmHg), be heated to 80 DEG C, be concentrated into relative density 1.10~1.20, it is standby;
(3), powder processed
Red ginseng 9g, tuber of pinellia 3g are amplified into 10 times, it is end together to crush, cross 80 mesh sieves, it is standby;
(4), dispensing
In 300,000 grades of dust proof workshops, medicinal powder is put in mixer together with aforementioned concentrate and is sufficiently mixed, stir;
(5), drying, crushing
The spice being well mixed is placed in into 60-70 DEG C of baking 4-5 hour in baking oven, is then crushed, cross 100 mesh sieves;
(6), granulate
The spice being well mixed is inserted in comminutor and is granulated;
(7), whole grain
The particle for making is carried out into whole grain, 35 mesh sieves are crossed;
(8), it is dried
Whole good particle is inserted in heat circulation drying oven, aeration-drying is to moisture < 8% at 80 DEG C;
(9) compressing tablet
Add magnesium stearate to be well mixed dry mixed gained medicine and be placed in compressing tablet in tablet press machine(Also can coating), every 0.5g;
B, packaging
During tablet is fitted into vial or vinyon bottle, then the bottle mounted box for installing, vanning, sterilizing (are adopted into 60Co irradiation, irradiation dose is 8kGy);
C, warehouse-in
Irradiated finished product is put in storage by the principle of first in first out.
CN201510750835.3A 2015-11-08 2015-11-08 Hui-nationality Chinese herbal red ginseng gastric cancer-treating tablet and preparation method thereof Withdrawn CN106668400A (en)

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