CN102327526A - Traditional Chinese medicine composition for lowering blood sugar - Google Patents
Traditional Chinese medicine composition for lowering blood sugar Download PDFInfo
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- CN102327526A CN102327526A CN201110311031A CN201110311031A CN102327526A CN 102327526 A CN102327526 A CN 102327526A CN 201110311031 A CN201110311031 A CN 201110311031A CN 201110311031 A CN201110311031 A CN 201110311031A CN 102327526 A CN102327526 A CN 102327526A
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Abstract
The invention discloses a traditional Chinese medicine composition for lowering blood sugar, which is prepared from rhizoma polygonati, rhizoma atractylodis macrocephalae, radix rehmanniae, rhizoma anemarrhenae, wolfberry bark, rhizoma alismatis, gypsum, radix trichosanthis, radix ophiopogonis, coix seed and licorice root in a certain proportion. The traditional Chinese medicine composition for lowering blood sugar has the effects of nourishing yin, moistening dryness, promoting salivation to quench thirst, strengthening the spleen and replenishing qi, removing dampness and promoting diuresis, and has the advantages of obvious curative effect and no toxic or side effect. The clinical observation and statistics on 200 patients indicate that the effective rate of patients taking the medicine for one treatment course is 92%, the effective rate of patients taking the medicine for two treatment courses is 95%, and the effective rate of patients taking the medicine for three treatment courses is 98%.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, especially a kind of effectively Chinese medicine composition of blood sugar lowering.
Background technology
Diabetes are a kind of commonly encountered diseases, are difficult to cure, and needs of patients is taken medicine for a long time, otherwise its complication often causes serious consequence.The diabetes Chinese medical discrimination belongs to the category of quenching one's thirst, and its pathogenesis mainly is YIN fluid deficiency, and scorching inclined to one side Sheng, the deficiency of YIN are this, and is scorching for marking.Production of dryness-heat in the interior, the dried liquid in Tianjin is withered, and QI and blood is not smooth, is the stasis of blood for a long time.Treatment of diabetes mainly is that blood sugar lowering is kept within normal range or stoped blood glucose further to raise, and clinical medicine commonly used has metformin hydrochloride and insoral at present, and the two is the biguanide hypoglycemic medicine; Its side effect mainly is a gastrointestinal reaction; Anorexia, bitter taste arranged, feel sick, symptoms such as vomiting, abdominal distention and diarrhoea, because of through liver metabolism, be prone to bring out lactic acidosis; Affect for the treatment of diabetics; Therefore, it is little to research and develop a kind of side effect, and the medicine of treating both the principal and secondary aspects of a disease is very helpful to treatment of diabetes.
Summary of the invention
Technical assignment of the present invention is to the problem of above-mentioned proposition a kind of hypoglycemic Chinese medicine composition to be provided, and it is nourshing Yin and drynsessmoistening prescription that this Chinese medicine composition has, promoting the production of body fluid to quench thirst, invigorating the spleen and benefiting QI, the effect of promoting diuresis to eliminate damp pathogen.
The present invention selects Rhizoma Polygonati, the Rhizoma Atractylodis Macrocephalae, Radix Rehmanniae, the Rhizoma Anemarrhenae, Cortex Lycii, Rhizoma Alismatis, Gypsum Fibrosum, Radix Trichosanthis, Radix Ophiopogonis, Semen Coicis, Radix Glycyrrhizae to make up; Make each efficacy of drugs produce synergism these drug regimens; Thereby effective blood sugar lowering; Control syrup patient's the state of an illness, raising diabetes patient's quality of life.
Wherein, Rhizoma Polygonati: be the dry rhizome of liliaceous plant Yunnan Rhizoma Polygonati (Polygonatum kingianum Coll. et Hemsl.), Rhizoma Polygonati (Polygonatum sibiricum Red.) or Polygonatum cyrtonema Hua (Polygonatum cyrtonema Hua.).Nature and flavor are sweet, and are flat.Return lung, spleen, kidney channel.Cure mainly deficiency of YIN chronic cough; The xeropulmonary cough; Insufficiency of the spleen weak; The lack of appetite xerostomia, the blood glucose that epinephrine is caused is too high to be remarkable inhibitory action.
The Rhizoma Atractylodis Macrocephalae: be the dry rhizome of feverfew Rhizoma Atractylodis Macrocephalae Atractylodes macrocephala Koidz..Nature and flavor are bitter, sweet, temperature.Return spleen, stomach warp.Have invigorating the spleen and benefiting QI, the effect of dampness diuretic, its decocting liquid has the oxidation utilization of glucose in the acceleration bodies and hypoglycemic activity is arranged.
Radix Rehmanniae: be the root of dicotyledon medicine scrophulariaceae rehmannia glutinosa plant or bosom celebrating Radix Rehmanniae.Nature and flavor sweetness and bitterness, cold.GUIXIN, liver, kidney channel.Effect with clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting.After its decoct, preserved material or pure extractum are irritated stomach or injection to rabbit, the hyperglycemia that can reduce euglycemia and cause by epinephrine, ammonia chloride.
The Rhizoma Anemarrhenae: be the monocotyledon Liliaceae Liliaceae Rhizoma Anemarrhenae
Anemarrhena asphodeloidesBge. dry rhizome.Nature and flavor are bitter, sweet, and are cold.Return lung, stomach, kidney channel.Has effect nourshing Yin and drynsessmoistening prescription, promoting the production of body fluid to quench thirst.Its Rhizoma Anemarrhenae polysaccharide A, B, C, D can make the blood glucose of normal mouse or hyperglycemia mice descend.
Cortex Lycii: be the root bark of matrimony vine of solanaceae plant Lycium chinense Mill..Cold in nature, sweet in the mouth.Go into lung, liver, kidney channel.Has heat clearing away, the effect of removing heat from blood.Pharmacological testing: irritate clothes Cortex Lycii decoct to rabbit, the blood glucose short time is raise, reduce lastingly then, do not recover as yet after 4~8 hours.
Rhizoma Alismatis: the dry tuber of Alismataceae (Alismataceae) plant Rhizoma Alismatis Alisma orientale (Samuels) Juzep..Nature and flavor are sweet, light, and are cold.Return kidney; Urinary bladder channel.Have promoting diuresis to eliminate damp pathogen, treating stranguria effect expels the heat-evil.
Gypsum Fibrosum: monoclinic system mineral, main chemical compositions are calcium sulfate (CaSO4).The property acrid-sweet flavor, cold.Go into lung, stomach warp.Have that relieving restlessness is quenched the thirst, the effect of heat-clearing and toxic substances removing.
Radix Trichosanthis: be the dry root of cucurbitaceous plant Fructus Trichosanthis Trichosanthes kirilowii Maxim. or trichosanthes rosthornii Harms Trichosanthes rosthornii Herms.Sweet, the little hardship of nature and flavor is slightly cold.Attach to the lung and stomach meridians.Have nourishing yin and purging fire, the effect of promoting the production of body fluid to quench thirst is used for the calentura excessive thirst, lung-heat type cough, interior-heat disease such as quench one's thirst.
Radix Ophiopogonis: be the Liliaceae Ophiopogon plant dried root of Radix Ophiopogonis.Sweet, the little hardship of nature and flavor is slightly cold.GUIXIN, lung, stomach warp.Has YIN nourishing and the production of body fluid promoting, the effect that lung moistening clears away heart-fire.Be used for dryness of the lung dry cough, Tianjin wound is thirsty, and interior-heat is quenched one's thirst, vexed insomnia, dryness of the intestine constipation.
Semen Coicis: be the seed of Semen Coicis, slightly sweet flavor is slightly cold, and goes into spleen, stomach, lung meridian.Have promoting diuresis to eliminate damp pathogen, strengthening the spleen and stomach, clearing away lung-heat, stopping leak and effect such as rush down.
Radix Glycyrrhizae: be dicotyledon pulse family Leguminosae Radix Glycyrrhizae
Glycyrrhiza uralensisFisch., Glycyrrhiza inflata Bat.
G. inflataOr Glycyrrhiza glabra L. Bat.,
G. glabraL. root and rhizome.Property is put down, and sweet in the mouth is returned 12 warps.Has invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, the effect of coordinating the actions of various ingredients in a prescription.
Medicine material consumption of the present invention is groped to sum up to draw through the inventor in a large number, and each raw material consumption is for all to have curative effect preferably in the following weight parts scope: 10-20 parts of Rhizoma Polygonatis, 10-20 parts of the Rhizoma Atractylodis Macrocephalaes, 10-20 parts of Radix Rehmanniae, 10-20 parts of the Rhizoma Anemarrhenaes, 10-20 parts of Cortex Lycii, 8-18 parts of Rhizoma Alismatis, 8-18 parts in Gypsum Fibrosum, 8-15 parts of Radix Trichosanthis, 8-18 parts of Radix Ophiopogonis, 8-18 parts of Semen Coicis, 5-10 parts in Radix Glycyrrhizae.
Wherein be preferably: 15 parts of Rhizoma Polygonatis, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts of Radix Rehmanniae, 15 parts of the Rhizoma Anemarrhenaes, 15 parts of Cortex Lycii, 12 parts of Rhizoma Alismatis, 12 parts in Gypsum Fibrosum, 10 parts of Radix Trichosanthis, 12 parts of Radix Ophiopogonis, 12 parts of Semen Coicis, 8 parts in Radix Glycyrrhizae.
Medicine of the present invention can adopt the conventional method of Chinese medicine preparation to be prepared into any conventional oral preparations, like pill, powder, tablet, oral liquid etc.For example can these crude drug pulverize mix homogeneously be processed powder takes after mixing it with water; Can use decocting,, add antiseptic and process oral liquid through filtering filtrating; Also can directly take decoction in case of necessity.
Medicine of the present invention has nourshing Yin and drynsessmoistening prescription, promoting the production of body fluid to quench thirst, invigorating the spleen and benefiting QI, the effect of promoting diuresis to eliminate damp pathogen; Evident in efficacy, without any side effects, according to clinical 200 routine patients are observed statistics; Take medicine obvious effective rate course of treatment obvious effective rate 92%, two course of treatment obvious effective rate 95%, three course of treatment 98% of the present invention.
The specific embodiment
Embodiment one, 10 parts of Rhizoma Polygonatis, 10 parts of the Rhizoma Atractylodis Macrocephalaes, 10 parts of Radix Rehmanniae, 10 parts of the Rhizoma Anemarrhenaes, 10 parts of Cortex Lycii, 8 parts of Rhizoma Alismatis, 8 parts in Gypsum Fibrosum, 8 parts of Radix Trichosanthis, 8 parts of Radix Ophiopogonis, 8 parts of Semen Coicis, 5 parts in Radix Glycyrrhizae.
Embodiment two, 15 parts of Rhizoma Polygonatis, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts of Radix Rehmanniae, 15 parts of the Rhizoma Anemarrhenaes, 15 parts of Cortex Lycii, 12 parts of Rhizoma Alismatis, 12 parts in Gypsum Fibrosum, 10 parts of Radix Trichosanthis, 12 parts of Radix Ophiopogonis, 12 parts of Semen Coicis, 8 parts in Radix Glycyrrhizae.
Embodiment three, 20 parts of Rhizoma Polygonatis, 20 parts of the Rhizoma Atractylodis Macrocephalaes, 20 parts of Radix Rehmanniae, 20 parts of the Rhizoma Anemarrhenaes, 20 parts of Cortex Lycii, 18 parts of Rhizoma Alismatis, 18 parts in Gypsum Fibrosum, 15 parts of Radix Trichosanthis, 18 parts of Radix Ophiopogonis, 18 parts of Semen Coicis, 10 parts in Radix Glycyrrhizae.
Be the clinical statistics data that the patient uses medicine of the present invention below:
One, physical data
Accept out-patient's 200 examples for medical treatment, male 125 people wherein, women 75 people, 51 years old mean age, fasting glucose is between 10-35 mmol/L, and average blood sugar is 18mmol/L.
Two, diagnostic criteria
The tcm diagnosis standard: the excessive thirst polydipsia, with drink with yearningly, dry pharynx dryness of the tongue, polyphagia polyphagia, the red constipation of urinating, red tongue with a little fluid yellow fur.Slippery and rapid pulse or stringy and rapid pulse.
The Western medicine diagnose standard: fasting glucose more than or equal to 6.1 mmol/L or after the meal 2h blood glucose more than or equal to 7.2 mmol/L
Three, Therapeutic Method
With embodiment two is example: the crude drug among the embodiment two is proportionally taken by weighing (daily dose) behind each crude drug, adopt conventional Chinese medicine decoction decocting method to decoct after, get soup and remove slag, take at twice, each is once sooner or later.10 days is a course of treatment.
Four, efficacy assessment standard
1, desirable control: fasting glucose < 6.1mmol/>L; 2h blood glucose < 7.2mmol/>L after the meal; 24h glucose in urine total amount < 5g.2, better control: fasting glucose < 7.2mmol/>L; 2h blood glucose < 8.3mmol/>L after the meal; 24h glucose in urine total amount < 10g.3, general control: fasting glucose < 8.3mmol/>L; 2h blood glucose < 10mmol/>L after the meal; 24h glucose in urine total amount < 15g.
4, invalid: fasting glucose>8.3 mmol/L; 2h blood glucose>10mmol/L after the meal; 24h glucose in urine total amount>15g.
Five, therapeutic outcome statistics
Claims (2)
1. the Chinese medicine composition of a blood sugar lowering is characterized in that being made up of following bulk drugs: 10-20 parts of Rhizoma Polygonatis, 10-20 parts of the Rhizoma Atractylodis Macrocephalaes, 10-20 parts of Radix Rehmanniae, 10-20 parts of the Rhizoma Anemarrhenaes, 10-20 parts of Cortex Lycii, 8-18 parts of Rhizoma Alismatis, 8-18 parts in Gypsum Fibrosum, 8-15 parts of Radix Trichosanthis, 8-18 parts of Radix Ophiopogonis, 8-18 parts of Semen Coicis, 5-10 parts in Radix Glycyrrhizae.
2. the Chinese medicine composition of blood sugar lowering according to claim 1 is characterized in that being made up of following bulk drugs: 15 parts of Rhizoma Polygonatis, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts of Radix Rehmanniae, 15 parts of the Rhizoma Anemarrhenaes, 15 parts of Cortex Lycii, 12 parts of Rhizoma Alismatis, 12 parts in Gypsum Fibrosum, 10 parts of Radix Trichosanthis, 12 parts of Radix Ophiopogonis, 12 parts of Semen Coicis, 8 parts in Radix Glycyrrhizae.
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN105106755A (en) * | 2015-09-11 | 2015-12-02 | 齐齐哈尔医学院 | Elderly hypoglycemia adjusting care agent and preparation method thereof |
CN113974044A (en) * | 2021-10-26 | 2022-01-28 | 康学春 | Hypoglycemic solid beverage of polygonatum kingianum thirst quenching drink and preparation method thereof |
Citations (2)
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CN1336185A (en) * | 2000-07-28 | 2002-02-20 | 雷学军 | Hypolycemic functional water containing natural medicine component and its compounding process |
CN101816770A (en) * | 2010-06-02 | 2010-09-01 | 泰一和浦(北京)中医药研究院有限公司 | Chinese medicinal composition for treating diabetes and preparation method thereof |
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Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN1336185A (en) * | 2000-07-28 | 2002-02-20 | 雷学军 | Hypolycemic functional water containing natural medicine component and its compounding process |
CN101816770A (en) * | 2010-06-02 | 2010-09-01 | 泰一和浦(北京)中医药研究院有限公司 | Chinese medicinal composition for treating diabetes and preparation method thereof |
Non-Patent Citations (2)
Title |
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李玉林等: "《糖尿病(消渴病)中医诊治荟萃——全国第五次中医糖尿病学术大会论文集》", 31 December 1999, article "影响血糖的中药" * |
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105106755A (en) * | 2015-09-11 | 2015-12-02 | 齐齐哈尔医学院 | Elderly hypoglycemia adjusting care agent and preparation method thereof |
CN105106755B (en) * | 2015-09-11 | 2021-09-10 | 齐齐哈尔医学院 | Hypoglycemic regulation nursing medicament for old people and preparation method thereof |
CN113974044A (en) * | 2021-10-26 | 2022-01-28 | 康学春 | Hypoglycemic solid beverage of polygonatum kingianum thirst quenching drink and preparation method thereof |
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