CN112841433A - Feeding composition for improving immunity of swinery and purifying vivotoxin and preparation method thereof - Google Patents
Feeding composition for improving immunity of swinery and purifying vivotoxin and preparation method thereof Download PDFInfo
- Publication number
- CN112841433A CN112841433A CN202011615132.7A CN202011615132A CN112841433A CN 112841433 A CN112841433 A CN 112841433A CN 202011615132 A CN202011615132 A CN 202011615132A CN 112841433 A CN112841433 A CN 112841433A
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- parts
- yeast
- silicate mineral
- feed composition
- ore pulp
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Links
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
-
- A—HUMAN NECESSITIES
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Abstract
The invention discloses a feeding composition for improving immunity of swinery and purifying vivotoxin and a preparation method thereof, wherein the composition comprises the following substances in parts by weight: 10-15 parts of tannic acid, 5-8 parts of sanguinarine, 15-20 parts of hyacinth reed root, 15-25 parts of astragalus membranaceus, 10-15 parts of rhizoma atractylodis macrocephalae, 7-10 parts of Chinese yam, 5-9 parts of epimedium herb, 1-11 parts of pogostemon cablin, 1-9 parts of isatis root, 2-8 parts of lonicera flower, 11-15 parts of scutellaria baicalensis, 15-25 parts of modified silicate minerals, 1-6 parts of yeast nucleotide, 15-25 parts of radix bupleuri, 1-9 parts of ephedra and 5-15 parts of almond.
Description
Technical Field
The invention relates to the field of feeds, in particular to a feed composition for improving the immunity of swinery and purifying vivotoxin and a preparation method thereof.
Background
With the continuous development of breeding technology, the taste and the nutritional value of the feed become more important, some artificial growth promoters and antibiotics for preventing digestive tract diseases are added into the feed in order to promote the growth of pigs, the components greatly reduce the quality of the feed, hidden dangers are left for the health of people, and the problem of influencing the immunity of a swinery mainly lies in providing nutrition and controlling mycotoxin.
Natural aluminosilicate zeolite, montmorillonite, diatomite, kaolin and the like have certain selective adsorption capacity on mycotoxin due to large specific surface area and ion adsorption capacity. However, the disadvantages of the physical methods are also quite evident, for example: the natural aluminosilicate minerals have small adsorption force, low efficiency, large feed capacity and certain adsorption on nutrient substances, so the effect of directly applying the natural aluminosilicate minerals to the feed is not good. Thus, natural aluminosilicates have been modified to improve their selective adsorption of mycotoxins. For example, hydrated sodium calcium aluminosilicate extracted from zeolite has better selective adsorption capacity on aflatoxin B1. However, when the hydrated sodium calcium aluminosilicate is used alone, the adsorption capacity of the hydrated sodium calcium aluminosilicate on other mycotoxins except aflatoxin is not strong, and the adsorption effect on zearalenone, ochratoxin A, T-2 and deoxynivalenol (namely vomitoxin) is not good.
The inventor finds that the nucleotide yeast and the modified silicate mineral have good spectrum mycotoxin adsorption capacity when being mixed, but the nutrition supply is not sufficient, and the quality of pork is influenced a little.
Disclosure of Invention
The invention aims to provide a feeding composition for improving the immunity of swinery and purifying vivotoxin and a preparation method thereof, and aims to solve at least one of the problems:
in a first aspect: a feeding composition for improving the immunity of swinery and purifying vivotoxin comprises the following substances in parts by weight: 10-15 parts of tannic acid, 5-8 parts of sanguinarine, 15-20 parts of hyacinth reed root, 15-25 parts of astragalus membranaceus, 10-15 parts of rhizoma atractylodis macrocephalae, 7-10 parts of Chinese yam, 5-9 parts of herba epimedii, 1-11 parts of pogostemon cablin, 1-9 parts of radix isatidis, 2-8 parts of lonicera flower, 11-15 parts of scutellaria baicalensis, 15-25 parts of modified silicate minerals, 1-6 parts of yeast nucleotides, 15-25 parts of radix bupleuri, 1-9 parts of ephedra and 5-15 parts of almond.
Preferably, the composition comprises the following materials in parts by weight: 12-14 parts of tannic acid, 5-7 parts of sanguinarine, 16-18 parts of water hyacinth reed root, 18-20 parts of astragalus membranaceus, 12-15 parts of rhizoma atractylodis macrocephalae, 8-10 parts of Chinese yam, 7-9 parts of herba epimedii, 5-10 parts of pogostemon cablin, 3-8 parts of radix isatidis, 3-6 parts of lonicera flower, 12-14 parts of scutellaria baicalensis, 18-22 parts of modified silicate mineral, 2-5 parts of yeast nucleotide, 18-22 parts of radix bupleuri, 3-6 parts of ephedra and 8-12 parts of almond.
Preferably, the composition comprises the following materials in parts by weight: 13 parts of tannic acid, 6 parts of sanguinarine, 17 parts of water hyacinth reed root, 19 parts of astragalus, 13 parts of rhizoma atractylodis macrocephalae, 9 parts of Chinese yam, 8 parts of epimedium, 8 parts of pogostemon cablin, 5 parts of isatis root, 4 parts of lonicera confusa, 13 parts of scutellaria baicalensis, 20 parts of modified silicate mineral, 3 parts of yeast nucleotide, 20 parts of radix bupleuri, 4 parts of ephedra and 10 parts of almond.
Preferably, the preparation method of the modified silicate mineral comprises the following steps:
1) adding silicate mineral clay raw ore and water into a ball mill for grinding, overflowing the formed slurry through a spiral classifier to remove impurity minerals, sending the slurry into a stirring barrel through a slurry pump, simultaneously adding a surfactant, and stirring at a high speed for 30min to obtain highly dispersed primary purified silicate mineral clay ore pulp;
2) purifying the ore pulp obtained in the step 1) by a cyclone classifier to obtain purified ore pulp;
3) adjusting the pH value of the purified ore pulp obtained in the step 2) to 4.5 by using HCl or adjusting the pH value of the ore pulp to 9.5 by using 1.0M NaOH solution, then adding an organic modifier, and stirring for 60 minutes to obtain organically modified purified and concentrated silicate mineral clay ore pulp;
4) dehydrating the organically modified, purified and concentrated silicate mineral clay ore pulp obtained in the step 3) to obtain viscous ore mud, transferring the viscous ore mud into a rotary kiln for drying, and grinding to obtain the modified silicate mineral after drying.
Preferably, the preparation method of the yeast nucleotide comprises the following steps:
1) inoculating yeast strains into a culture medium, and continuously fermenting to obtain a fermentation liquid containing yeast strains;
2) centrifuging the fermentation liquor obtained in the step 1) to obtain a yeast concentrated phase, and adding water to prepare a yeast solution;
3) heating the yeast liquid obtained in the step 2) to 70 ℃, adding protease for enzymolysis, and dissociating ribonucleic acid to the extracellular space;
4) adjusting the temperature of the material obtained in the step 3) to 60 ℃, and then adding a nuclease solution for enzymolysis to obtain an enzymolysis solution;
5) drying the enzymatic hydrolysate obtained in the step 4) to prepare the nucleotide yeast.
Preferably, the feed composition further comprises the following substances in parts by weight: 6 parts of sodium diacetate and 15 parts of seaweed.
In a second aspect, the invention provides a preparation method of a feeding composition for improving the immunity of swinery and purifying vivotoxin, which comprises the following steps:
1) grinding rhizoma Curculiginis, radix astragali, rhizoma Atractylodis Macrocephalae, rhizoma Dioscoreae, herba Epimedii, herba Pogostemonis, radix Isatidis 3-8 parts, flos Lonicerae, and radix Scutellariae, and sieving with 100 mesh sieve to obtain powder;
2) mixing the powder obtained in the step 1) with the modified silicate mineral and the yeast nucleotide, stirring for 30min, adding the rest raw materials, and stirring for 20min to obtain the feed composition for improving the immunity of the swinery and purifying the toxin in vivo.
Tannic acid: tannic acid, also called tannic acid, is an organic substance of formula C76H52O46Is a tannin obtained from Galla chinensis. Is yellow or light brown light amorphous powderOr a scale; no odor, slight special odor, and extremely astringent taste. Soluble in water and ethanol, easily soluble in glycerol, and hardly soluble in diethyl ether, chloroform or benzene. The water solution and the ferric salt solution change into blue-black when meeting each other, and the color change can be delayed by adding sodium sulfite. In industry, tannic acid is used in great quantities for tanning and making blue inks. Tannins are capable of coagulating proteins. The chemical treatment of raw pigskin and raw cowskin with tannic acid can coagulate the soluble protein in the raw skin.
Sanguinarine: the antibacterial sanguinarine has effects of preventing and treating fish diseases caused by some bacteria. The antibacterial activity research shows that sanguinarine has different degrees of inhibition effects on 6 strains of aquatic pathogenic bacteria, wherein the activity on the hydrophile of Aeromonas hydrophila is strongest, and the MIC and MBC are 12.5mg/L and 25mg/L respectively. The activity to Vibrio harveyi, Vibrio anguillarum and Aeromonas salmonicida subspecies Steiner is the weakest, and the MIC and MBC are 50mg/L and lOOmg/L respectively. Research on Yujianping and the like (2006) shows that sanguinarine hydrochloride has strong antibacterial effect on trichoderma, penicillium, rhizopus, aspergillus flavus, aspergillus niger, aspergillus oryzae, mucor and yeast, and the sanguinarine hydrochloride has very low minimum antibacterial concentration on 8 fungi, wherein the minimum antibacterial concentration of the penicillium and the mucor is 80g/mL, and the minimum antibacterial concentration of the trichoderma, rhizopus, aspergillus flavus, aspergillus niger, aspergillus oryzae and yeast is less than 40ug/mL, and the sanguinarine hydrochloride is used as a plant source natural antibacterial agent and has wide antibacterial spectrum and very obvious effect.
Water hyacinth root: water hyacinth reed root, name of traditional Chinese medicine. Is root and rhizome of Asteraceae plant and Gymnosphaera indica himalaicium Edgew. Distributed all over the country. Has the effects of dispersing lung qi, relieving asthma, inducing diuresis, relieving swelling, removing blood stasis and relieving pain. Can be used for treating cough, asthma, edema, dysuria, puerperal blood stasis, abdominal pain, and traumatic injury.
Herba epimedii: modern researches show that epimedium contains icariin, volatile oil, ceryl alcohol, phytosterol, tannin, vitamin E and other components. Can excite sexual function, and promote semen secretion for animals. It also has blood pressure lowering (peripheral vasodilation inducing), blood glucose lowering, diuretic, antitussive, expectorant, and vitamin E-like effects. Pharmacological experimental research shows that epimedium can increase blood flow of heart and cerebral vessels, promote hematopoiesis, immunity and bone metabolism, and has the functions of resisting senility, resisting tumor, etc. The research of the Singapore medical experts shows that the epimedium can effectively kill breast cancer cells, but the epimedium is still required to be further researched clinically.
Dense honeysuckle flower: perennial half evergreen winding shrubs of Mi Er flowers. Because it is silvery white at the beginning of blooming, it turns yellow after two or three days, the new and old are related to each other, and the yellow and white are related to each other, so that it is called "honeysuckle flower" as white at the beginning of blooming, just like silver, it turns yellow and gold after 2-3 months, the new and old are related to each other, and the yellow and white are related to each other, so it is called "honeysuckle flower" as a good name. Recorded in gang mu Shi Yi (compendium Leisha) honeysuckle flower can stimulate appetite, relieve epigastric distention, clear away heat and toxic material, treat thirst due to summer-heat and heat-toxin scabies. The herbal tea prepared from the honeysuckle flowers is taken in folk, is fresh and delicious, prevents heatstroke, and has certain curative effect on cold and intestinal infectious diseases.
Has the advantages that:
according to the invention, the modified silicate mineral is matched with the nucleotide yeast to ensure the adsorption of the mould, and then through the matching of various substances, the nutritional requirement for the growth of live pigs is met, other common diseases of live pigs are reduced, and the taste of pork is improved.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are a part of the embodiments of the present invention, but not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without any inventive step, are within the scope of the present invention.
Example 1
The feed composition for improving the immunity of a swinery and purifying vivotoxin is characterized by comprising the following substances in parts by weight: 10 parts of tannic acid, 5 parts of sanguinarine, 15 parts of water hyacinth reed root, 15 parts of astragalus, 10 parts of rhizoma atractylodis macrocephalae, 7 parts of Chinese yam, 5 parts of epimedium, 1 part of pogostemon cablin, 1 part of isatis root, 2 parts of lonicera confusa, 11 parts of scutellaria baicalensis, 15 parts of modified silicate mineral, 1 part of yeast nucleotide, 15 parts of radix bupleuri, 1 part of ephedra and 5 parts of almond.
The preparation method of the modified silicate mineral comprises the following steps:
1) adding silicate mineral clay raw ore and water into a ball mill for grinding, overflowing the formed slurry through a spiral classifier to remove impurity minerals, sending the slurry into a stirring barrel through a slurry pump, simultaneously adding a surfactant, and stirring at a high speed for 30min to obtain highly dispersed primary purified silicate mineral clay ore pulp;
2) purifying the ore pulp obtained in the step 1) by a cyclone classifier to obtain purified ore pulp;
3) adjusting the pH value of the purified ore pulp obtained in the step 2) to 4.5 by using HCl or adjusting the pH value of the ore pulp to 9.5 by using 1.0M NaOH solution, then adding an organic modifier, and stirring for 60 minutes to obtain organically modified purified and concentrated silicate mineral clay ore pulp;
4) dehydrating the organically modified, purified and concentrated silicate mineral clay ore pulp obtained in the step 3) to obtain viscous ore mud, transferring the viscous ore mud into a rotary kiln for drying, and grinding to obtain the modified silicate mineral after drying.
The preparation method of the yeast nucleotide comprises the following steps:
1) inoculating yeast strains into a culture medium, and continuously fermenting to obtain a fermentation liquid containing yeast strains;
2) centrifuging the fermentation liquor obtained in the step 1) to obtain a yeast concentrated phase, and adding water to prepare a yeast solution;
3) heating the yeast liquid obtained in the step 2) to 70 ℃, adding protease for enzymolysis, and dissociating ribonucleic acid to the extracellular space;
4) adjusting the temperature of the material obtained in the step 3) to 60 ℃, and then adding a nuclease solution for enzymolysis to obtain an enzymolysis solution;
5) drying the enzymatic hydrolysate obtained in the step 4) to prepare the nucleotide yeast.
Example 2
The feed composition for improving the immunity of a swinery and purifying vivotoxin is characterized by comprising the following substances in parts by weight: 15 parts of tannic acid, 8 parts of sanguinarine, 20 parts of water hyacinth root, 25 parts of astragalus, 15 parts of rhizoma atractylodis macrocephalae, 10 parts of Chinese yam, 9 parts of epimedium, 11 parts of pogostemon cablin, 9 parts of isatis root, 8 parts of lonicera confusa, 15 parts of scutellaria baicalensis, 25 parts of modified silicate mineral, 6 parts of yeast nucleotide, 25 parts of radix bupleuri, 9 parts of ephedra and 15 parts of almond.
Other preparation methods and preparation conditions were the same as in example 1.
Example 3
The feed composition for improving the immunity of a swinery and purifying vivotoxin is characterized by comprising the following substances in parts by weight: 12 parts of tannic acid, 5 parts of sanguinarine, 16 parts of water hyacinth reed root, 18 parts of astragalus root, 12 parts of rhizoma atractylodis macrocephalae, 8 parts of Chinese yam, 7 parts of epimedium herb, 5 parts of pogostemon cablin, 3 parts of isatis root, 3 parts of lonicera flower, 12 parts of scutellaria root, 18 parts of modified silicate mineral, 2 parts of yeast nucleotide, 18 parts of bupleurum root, 3 parts of ephedra and 8 parts of almond.
Other preparation methods and preparation conditions were the same as in example 1.
Example 4
The feed composition for improving the immunity of a swinery and purifying vivotoxin is characterized by comprising the following substances in parts by weight: 14 parts of tannic acid, 7 parts of sanguinarine, 18 parts of water hyacinth root, 20 parts of astragalus, 15 parts of rhizoma atractylodis macrocephalae, 10 parts of Chinese yam, 9 parts of epimedium herb, 10 parts of pogostemon cablin, 8 parts of isatis root, 6 parts of lonicera flower, 14 parts of scutellaria baicalensis, 22 parts of modified silicate mineral, 5 parts of yeast nucleotide, 22 parts of radix bupleuri, 6 parts of ephedra and 12 parts of almond.
Other preparation methods and preparation conditions were the same as in example 1.
Example 5
The feed composition for improving the immunity of a swinery and purifying vivotoxin is characterized by comprising the following substances in parts by weight: 13 parts of tannic acid, 6 parts of sanguinarine, 17 parts of water hyacinth reed root, 19 parts of astragalus, 13 parts of rhizoma atractylodis macrocephalae, 9 parts of Chinese yam, 8 parts of epimedium, 8 parts of pogostemon cablin, 5 parts of isatis root, 4 parts of lonicera confusa, 13 parts of scutellaria baicalensis, 20 parts of modified silicate mineral, 3 parts of yeast nucleotide, 20 parts of radix bupleuri, 4 parts of ephedra, 10 parts of almond, 6 parts of sodium diacetate and 15 parts of seaweed.
Other preparation methods and preparation conditions were the same as in example 1.
Comparative example 1
Comparative example 1 is different from example 1 only in that water hyacinth root is not added, and other preparation methods and preparation conditions are the same as those of example 1.
Comparative example 2
Comparative example 2 is different from example 1 only in that epimedium is not added, and other preparation methods and preparation conditions are the same as those of example 1.
Comparative example 3
Comparative example 3 differs from example 1 only in that the honeysuckle flower is not added, and the other preparation methods and preparation conditions are the same as those of example 1.
Comparative example 4
Comparative example 4 is different from example 1 only in that no bupleurum is added, and other preparation methods and preparation conditions are consistent with example 1.
The feed compositions obtained in examples 1 to 5 and comparative examples 1 to 4 were added to the uniformly purchased pig feed at an addition rate of 2 percent to obtain corresponding pig feeds containing the feed compositions. In the case of the live pig breeding, the examples 1 to 5 and the comparative examples 1 to 4 show no toxic symptoms such as food refusal, vomiting, false oestrus and the like.
And (3) testing: the test was divided into 9 groups of 3 replicates each of 3 pigs, 9 total pigs per group, according to examples 1 to 5 and comparative examples 1 to 4, and the pigs used in the test were all congeneric pigs of substantially the same age at birth and initial body weight of 70 + -2 kg, for a period of two months.
The test method comprises the following steps: cleaning and disinfecting the pen house before the test, recording the ear size of the test pig, pre-feeding the test pig for 7 days after the test pig enters the test pig, gradually adding the feed prepared in the corresponding example or the comparative example from the original feed in the first four days, and completely feeding the corresponding feed in the last 3 days. And (3) weighing 1 pig in the current morning on an empty stomach in the formal period, wherein the formal period is 60 days, and after the test is finished, weighing 33 pigs in the next morning on an empty stomach, and slaughtering, sampling and measuring.
The test results are shown in Table 1 below
TABLE 1
As can be seen from Table 1, the fat reducing effect is achieved in the examples 1 to 5, the fat content of the muscles in the examples 1 to 5 is obviously reduced compared with that in the comparative example 4, the moisture difference is not large, the feed provided by the invention maintains the nutritional ingredients of pork in the fat reducing process, and compared with the example 1 in the comparative examples 1 to 4, the water hyacinth reed root, the epimedium herb, the lonicera flower and the radix bupleuri are important components in ensuring the nutritional ingredients of pork and reducing fat.
Finally, it should be noted that: the above examples are only intended to illustrate the technical solution of the present invention, but not to limit it; although the present invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; and such modifications or substitutions do not depart from the spirit and scope of the corresponding technical solutions of the embodiments of the present invention.
Claims (8)
1. A feeding composition for improving the immunity of swinery and purifying vivotoxin is characterized by comprising the following substances in parts by weight: 10-15 parts of tannic acid, 5-8 parts of sanguinarine, 15-20 parts of hyacinth reed root, 15-25 parts of astragalus membranaceus, 10-15 parts of rhizoma atractylodis macrocephalae, 7-10 parts of Chinese yam, 5-9 parts of herba epimedii, 1-11 parts of pogostemon cablin, 1-9 parts of radix isatidis, 2-8 parts of lonicera flower, 11-15 parts of scutellaria baicalensis, 15-25 parts of modified silicate mineral, 1-6 parts of yeast nucleotide, 15-25 parts of radix bupleuri, 1-9 parts of ephedra and 5-15 parts of almond.
2. The feed composition of claim 1, comprising in parts by weight: 12-14 parts of tannic acid, 5-7 parts of sanguinarine, 16-18 parts of water hyacinth reed root, 18-20 parts of astragalus membranaceus, 12-15 parts of rhizoma atractylodis macrocephalae, 8-10 parts of Chinese yam, 7-9 parts of herba epimedii, 5-10 parts of pogostemon cablin, 3-8 parts of radix isatidis, 3-6 parts of lonicera flower, 12-14 parts of scutellaria baicalensis, 18-22 parts of modified silicate mineral, 2-5 parts of yeast nucleotide, 18-22 parts of radix bupleuri, 3-6 parts of ephedra and 8-12 parts of almond.
3. The feed composition of claim 1, comprising in parts by weight: 13 parts of tannic acid, 6 parts of sanguinarine, 17 parts of water hyacinth reed root, 19 parts of astragalus, 13 parts of rhizoma atractylodis macrocephalae, 9 parts of Chinese yam, 8 parts of epimedium, 8 parts of pogostemon cablin, 5 parts of isatis root, 4 parts of lonicera confusa, 13 parts of scutellaria baicalensis, 20 parts of modified silicate mineral, 3 parts of yeast nucleotide, 20 parts of radix bupleuri, 4 parts of ephedra and 10 parts of almond.
4. The feed composition of claim 1, wherein the modified silicate mineral is prepared by a process comprising the steps of:
1) adding silicate mineral clay raw ore and water into a ball mill for grinding, overflowing the formed slurry through a spiral classifier to remove impurity minerals, sending the slurry into a stirring barrel through a slurry pump, simultaneously adding a surfactant, and stirring at a high speed for 30min to obtain highly dispersed primary purified silicate mineral clay ore pulp;
2) purifying the ore pulp obtained in the step 1) by a cyclone classifier to obtain purified ore pulp;
3) adjusting the pH value of the purified ore pulp obtained in the step 2) to 4.5 by using HCl or adjusting the pH value of the ore pulp to 9.5 by using 1.0M NaOH solution, then adding an organic modifier, and stirring for 60 minutes to obtain organically modified purified and concentrated silicate mineral clay ore pulp;
4) dehydrating the organically modified, purified and concentrated silicate mineral clay ore pulp obtained in the step 3) to obtain viscous ore mud, transferring the viscous ore mud into a rotary kiln for drying, and grinding to obtain the modified silicate mineral after drying.
5. The feed composition of claim 1, wherein the yeast nucleotide is prepared by a method comprising the steps of:
1) inoculating yeast strains into a culture medium, and continuously fermenting to obtain a fermentation liquid containing yeast strains;
2) centrifuging the fermentation liquor obtained in the step 1) to obtain a yeast concentrated phase, and adding water to prepare a yeast solution;
3) heating the yeast liquid obtained in the step 2) to 70 ℃, adding protease for enzymolysis, and dissociating ribonucleic acid to the extracellular space;
4) adjusting the temperature of the material obtained in the step 3) to 60 ℃, and then adding a nuclease solution for enzymolysis to obtain an enzymolysis solution;
5) drying the enzymatic hydrolysate obtained in the step 4) to prepare the nucleotide yeast.
6. The feed composition as claimed in claim 3 further comprising, in parts by weight: 6 parts of sodium diacetate and 15 parts of seaweed.
7. A method for preparing a herd immunity enhancing and toxin purging feed composition of any of claims 1-6 comprising the steps of:
1) grinding rhizoma Curculiginis, radix astragali, rhizoma Atractylodis Macrocephalae, rhizoma Dioscoreae, herba Epimedii, herba Pogostemonis, radix Isatidis 3-8 parts, flos Lonicerae, and radix Scutellariae, and sieving with 100 mesh sieve to obtain powder;
2) mixing the powder obtained in the step 1) with the modified silicate mineral and the yeast nucleotide, stirring for 30min, adding the rest raw materials, and stirring for 20min to obtain the feed composition for improving the immunity of the swinery and purifying the vivotoxin.
8. The feed composition as claimed in claim 1 in an amount of 2%.
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Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1843151A (en) * | 2006-03-16 | 2006-10-11 | 上海交通大学 | Composite mold toxin sorbent |
CN103583823A (en) * | 2013-11-07 | 2014-02-19 | 北京大北农科技集团股份有限公司 | Mold removal agent for feed and preparation method and feed additive thereof |
CN104068217A (en) * | 2014-06-12 | 2014-10-01 | 广州成诺生物科技有限公司 | Anti-mycotoxin feed additive for cattle |
CN107307205A (en) * | 2017-07-07 | 2017-11-03 | 深圳市金新农科技股份有限公司 | It is a kind of for the compositions of additives of pig starter feed, compound premix and nonreactive pig starter feed |
CN107396887A (en) * | 2017-08-28 | 2017-11-28 | 临沧保林种植有限责任公司 | A kind of pig-breeding method |
CN107412511A (en) * | 2017-05-08 | 2017-12-01 | 河南省中兽医药研究院有限公司 | It is a kind of to be used to improve pig body immunity, the Chinese medicine composition for preventing and treating virus diseases of pigs and products thereof and feeding method |
CN109527341A (en) * | 2019-01-02 | 2019-03-29 | 中国科学院兰州化学物理研究所 | A kind of multifunctional antibiotic takes off mould dose |
CN109527340A (en) * | 2019-01-02 | 2019-03-29 | 中国科学院兰州化学物理研究所 | A kind of silicates functional form mold toxin sorbent |
CN112057517A (en) * | 2020-10-23 | 2020-12-11 | 得利斯集团有限公司 | Traditional Chinese medicine composition for improving survival rate of weaned piglets, preparation method and feeding method |
-
2020
- 2020-12-31 CN CN202011615132.7A patent/CN112841433A/en active Pending
Patent Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1843151A (en) * | 2006-03-16 | 2006-10-11 | 上海交通大学 | Composite mold toxin sorbent |
CN103583823A (en) * | 2013-11-07 | 2014-02-19 | 北京大北农科技集团股份有限公司 | Mold removal agent for feed and preparation method and feed additive thereof |
CN104068217A (en) * | 2014-06-12 | 2014-10-01 | 广州成诺生物科技有限公司 | Anti-mycotoxin feed additive for cattle |
CN107412511A (en) * | 2017-05-08 | 2017-12-01 | 河南省中兽医药研究院有限公司 | It is a kind of to be used to improve pig body immunity, the Chinese medicine composition for preventing and treating virus diseases of pigs and products thereof and feeding method |
CN107307205A (en) * | 2017-07-07 | 2017-11-03 | 深圳市金新农科技股份有限公司 | It is a kind of for the compositions of additives of pig starter feed, compound premix and nonreactive pig starter feed |
CN107396887A (en) * | 2017-08-28 | 2017-11-28 | 临沧保林种植有限责任公司 | A kind of pig-breeding method |
CN109527341A (en) * | 2019-01-02 | 2019-03-29 | 中国科学院兰州化学物理研究所 | A kind of multifunctional antibiotic takes off mould dose |
CN109527340A (en) * | 2019-01-02 | 2019-03-29 | 中国科学院兰州化学物理研究所 | A kind of silicates functional form mold toxin sorbent |
CN112057517A (en) * | 2020-10-23 | 2020-12-11 | 得利斯集团有限公司 | Traditional Chinese medicine composition for improving survival rate of weaned piglets, preparation method and feeding method |
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