CN104367670A - Traditional Chinese medicine granules for preventing and treating piglet bacterial enteritis and preparation method thereof - Google Patents
Traditional Chinese medicine granules for preventing and treating piglet bacterial enteritis and preparation method thereof Download PDFInfo
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- CN104367670A CN104367670A CN201410608124.8A CN201410608124A CN104367670A CN 104367670 A CN104367670 A CN 104367670A CN 201410608124 A CN201410608124 A CN 201410608124A CN 104367670 A CN104367670 A CN 104367670A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/488—Pueraria (kudzu)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
- A61K36/575—Magnolia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
Abstract
The invention discloses traditional Chinese medicine granules for preventing and treating piglet bacterial enteritis. The granules are characterized by being prepared from the following medicinal materials in parts by weight: 6-11 parts of kudzu vine root, 6-11 parts of scutellaria baicalensis, 4-9 parts of poria cocos, 3-7 parts of mangnolia officinalis, 2-5 parts of pericarpium citri reticulatae and 1-4 parts of licorice root. The traditional Chinese medicine granules for preventing and treating piglet bacterial enteritis are provided to the breeding industry, have the characteristics of quick response, exact curative effect, no drug residue and no toxic or side effect, and are convenient to transport and convenient to use.
Description
Technical field
The present invention relates to veterinary drug technical field, particularly relating to a kind of Chinese medicine granules for preventing and treating piglet bacillary enteritis and preparation method thereof.
Background technology
Piglet bacillary enteritis is piglet red dysentery again, is the acute infectious disease of the newborn piglet caused by C type clostridieum welchii.This bacterium extensively exists in the environment, also has in the intestinal of some sows, contacts contaminated environment very soon, this bacterium is swallowed digestive tract and infection morbidity after piglet birth.The pig of any kind to the equal susceptible of primary disease, but mainly occurs in the piglet of 1 ~ 3 age in days, little morbidity more than 1 week age.This sick rapid onset, the course of disease is short, and mortality rate is high, reaches more than 50% ~ 90%, and primary disease does not have seasonality, and within 1 year four, joint all can occur.
Piglet bacillary enteritis is divided into the most acute, subacute type and chronic type.Most acute: piglet is come into being just morbidity on the same day, and can occur hemorrhagic diarrhea (dysentery), rear quarters sticks band blood loose stool.Sick pig lassitude, rocks on foot, collapse immediately or stupor, to twitch and dead; Part piglet is exhaustion death without dysentery.Acute: the course of disease generally can maintain about 2 days, the bronzing water sample loose stool of drawstring blood, wherein containing Lycoperdon polymorphum Vitt slough fragment, sick pig rapid dehydration, to become thin, final exhaustion is dead.Subacute type: morbidity piglet is generally dead at nascent latter 5 ~ 7 days; Sick pig starts spirit, appetite is fair, the non hemorrhagic diarrhoea of persistence, and feces starts as yellow soft stool, after become clear water sample, and containing slough fragment, like congee sample; With disease, sick pig becomes thin gradually, dewaters, death in 5 ~ 7 days after birth.Chronic type: one to several weeks of the course of disease, in intermittent or persistent diarrhea, feces is lark, mucus shape, and rear quarters sticks the incrustation of feces.Sick pig poor growth, dysplasia, becomes thin, final dead or formation cad pig.
At present, the relevant report of the Chinese medicine preparation of the Chinese medicine granules about control piglet bacillary enteritis is not also had.
Summary of the invention
The object of the invention is the technological deficiency for existing in prior art, and a kind of Chinese medicine granules for preventing and treating piglet bacillary enteritis and preparation method thereof is provided.
The technical scheme adopted for realizing object of the present invention is: a kind of Chinese medicine granules for preventing and treating piglet bacillary enteritis, it is characterized in that, with weight parts, being made up of following medicinal materials: Radix Puerariae 6 ~ 11 parts, Radix Scutellariae 6 ~ 11 parts, 4 ~ 9 parts, Poria, Cortex Magnoliae Officinalis 3 ~ 7 parts, Pericarpium Citri Reticulatae 2 ~ 5 parts, 1 ~ 4 part, Radix Glycyrrhizae.
Preferably, above-mentioned Chinese medicine granules, with weight parts, is made up of following medicinal materials: Radix Puerariae 10 parts, Radix Scutellariae 9 parts, 9 parts, Poria, Cortex Magnoliae Officinalis 5 parts, Pericarpium Citri Reticulatae 5 parts, 2 parts, Radix Glycyrrhizae.
For preventing and treating a preparation method for the Chinese medicine granules of piglet bacillary enteritis, it is characterized in that comprising the following steps:
(1) following medicinal materials is taken by weight: Radix Puerariae 6 ~ 11 parts, Radix Scutellariae 6 ~ 11 parts, 4 ~ 9 parts, Poria, Cortex Magnoliae Officinalis 3 ~ 7 parts, Pericarpium Citri Reticulatae 2 ~ 5 parts, 1 ~ 4 part, Radix Glycyrrhizae;
(2) by the medical material that step (1) takes, add the water of medical material 10 times amount, decoct 2 times, 1.5 hours first times, second time 1 hour, collecting decoction, filter, be concentrated into relative density 1.28 (80 DEG C), dry rear pulverizing for 60 ~ 70 DEG C, add sucrose, mixing, makes granule and crosses 10 mesh sieves, 60 DEG C of oven dry, after 10 mesh sieves, to obtain final product.
Described Chinese medicinal material all meets " Chinese veterinary pharmacopoeia " version two ministerial standard in 2010.
Composition principle of the present invention is: Radix Puerariae expelling pathogenic factors from muscles for reducing heat, rash, yang invigorating antidiarrheal; Radix Scutellariae heat clearing and damp drying, eliminating fire and detoxication, hemostasis; Poria promoting diuresis to eliminate damp pathogen, spleen invigorating; The expectorant of Cortex Magnoliae Officinalis dampness, the therapeutic method to keep the adverse QI flowing downwards is except full; Pericarpium Citri Reticulatae regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm; Radix Glycyrrhizae invigorating the spleen and replenishing QI, regulating QI to relieve pain, heat-clearing and toxic substances removing, coordinating the actions of various ingredients in a prescription.All medicines share, clearing away heat-fire, and dampness is detoxified, effect of hemostasis antidiarrheal.
Beneficial effect of the present invention: for aquaculture provides a kind of Chinese medicine granules for preventing and treating piglet bacillary enteritis, there is instant effect, determined curative effect, no drug residue, feature without any side effects, and convenient transportation, easy to use.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is described in further detail.Should be appreciated that specific embodiment described herein only in order to explain the present invention, be not intended to limit the present invention.
Embodiment 1
Prevent and treat a Chinese medicine granules for piglet bacillary enteritis, with weight parts, be made up of following medicinal materials: Radix Puerariae 6 parts, Radix Scutellariae 11 parts, 6 parts, Poria, Cortex Magnoliae Officinalis 5 parts, Pericarpium Citri Reticulatae 5 parts, 3 parts, Radix Glycyrrhizae.
The preparation method of the Chinese medicine granules of above-mentioned control piglet bacillary enteritis, carries out as follows; By the Six-element medical material taken above, add the water of medical material 10 times amount, decoct 2 times, 1.5 hours first times, second time 1 hour, collecting decoction, filter, be concentrated into relative density 1.28 (80 DEG C), dry rear pulverizing for 60 ~ 70 DEG C, add sucrose, mixing, makes granule and crosses 10 mesh sieves (sieve aperture internal diameter: 2000 μm ± 70 μm), 60 DEG C of oven dry, after 10 mesh sieves (sieve aperture internal diameter: 2000 μm ± 70 μm), to obtain final product.
Embodiment 2
Prevent and treat a Chinese medicine granules for piglet bacillary enteritis, with weight parts, be made up of following medicinal materials: Radix Puerariae 11 parts, Radix Scutellariae 6 parts, 4 parts, Poria, Cortex Magnoliae Officinalis 7 parts, Pericarpium Citri Reticulatae 2 parts, 1 part, Radix Glycyrrhizae.
The preparation method of the Chinese medicine granules of above-mentioned control piglet bacillary enteritis, is prepared by step in embodiment 1.
Embodiment 3
Prevent and treat a Chinese medicine granules for piglet bacillary enteritis, with weight parts, be made up of following medicinal materials: Radix Puerariae 10 parts, Radix Scutellariae 9 parts, 9 parts, Poria, Cortex Magnoliae Officinalis 5 parts, Pericarpium Citri Reticulatae 5 parts, 2 parts, Radix Glycyrrhizae.
Be prepared by step in embodiment 1.
Embodiment 4
Prevent and treat a Chinese medicine granules for piglet bacillary enteritis, with weight parts, be made up of following medicinal materials: Radix Puerariae 7 parts, Radix Scutellariae 7 parts, 5 parts, Poria, Cortex Magnoliae Officinalis 3 parts, Pericarpium Citri Reticulatae 3 parts, 4 parts, Radix Glycyrrhizae.
Be prepared by step in embodiment 1.
Clinical trial:
In JIUYUE, 2012, Hebei self-employed pig raiser, piglet sudden death 2 piglets of 10 ages in days of 50 births, all the other pig lassitudes, rock on foot, and in intermittent or persistent diarrhea, feces is lark, mucus shape, and rear quarters sticks the incrustation of feces.Analyse the visible thoracic cavity of dead pig and there is volume cherry-red hydrops in abdominal cavity, intestinal tube mucosa has necrotic area, and has petechia, intestinal serous coat mesenterium ventrale and mesenteric lymph have the features such as minute bubbles, are diagnosed as piglet bacillary enteritis.
Administering mode: spice, adds 1kg feedstuff by 3g, continuous use 5 days.
Continuous this medicine of use is after 5 days, and piglet mental restoration is normal, and there are no intermittent diarrhea, stool colour is normal, and rear-guard is there are no the incrustation of feces.
The above is only the preferred embodiment of the present invention; it should be pointed out that for those skilled in the art, under the premise without departing from the principles of the invention; can also make some improvements and modifications, these improvements and modifications also should be considered as protection scope of the present invention.
Claims (4)
1. for preventing and treating a Chinese medicine granules for piglet bacillary enteritis, it is characterized in that, with weight parts, being made up of following medicinal materials: Radix Puerariae 6 ~ 11 parts, Radix Scutellariae 6 ~ 11 parts, 4 ~ 9 parts, Poria, Cortex Magnoliae Officinalis 3 ~ 7 parts, Pericarpium Citri Reticulatae 2 ~ 5 parts, 1 ~ 4 part, Radix Glycyrrhizae.
2. a kind of Chinese medicine granules for preventing and treating piglet bacillary enteritis according to claim 1, it is characterized in that described Chinese medicine granules is with weight parts, is made up of following medicinal materials: Radix Puerariae 10 parts, Radix Scutellariae 9 parts, 9 parts, Poria, Cortex Magnoliae Officinalis 5 parts, Pericarpium Citri Reticulatae 5 parts, 2 parts, Radix Glycyrrhizae.
3. the preparation method of a kind of Chinese medicine granules for preventing and treating piglet bacillary enteritis according to claim 1, is characterized in that comprising the following steps:
(1) following medicinal materials is taken by weight: Radix Puerariae 6 ~ 11 parts, Radix Scutellariae 6 ~ 11 parts, 4 ~ 9 parts, Poria, Cortex Magnoliae Officinalis 3 ~ 7 parts, Pericarpium Citri Reticulatae 2 ~ 5 parts, 1 ~ 4 part, Radix Glycyrrhizae;
(2) by the medical material that step (1) takes, add the water of medical material 10 times amount, decoct 2 times, 1.5 hours first times, second time 1 hour, collecting decoction, filter, be concentrated into relative density 1.28 (80 DEG C), dry rear pulverizing for 60 ~ 70 DEG C, add sucrose, mixing, makes granule and crosses 10 mesh sieves, 60 DEG C of oven dry, after 10 mesh sieves, to obtain final product.
4. the preparation method of a kind of Chinese medicine granules for preventing and treating piglet bacillary enteritis according to claim 3, is characterized in that medical material that described step (1) takes is with weight parts: Radix Puerariae 10 parts, Radix Scutellariae 9 parts, 9 parts, Poria, Cortex Magnoliae Officinalis 5 parts, Pericarpium Citri Reticulatae 5 parts, 2 parts, Radix Glycyrrhizae.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410608124.8A CN104367670A (en) | 2014-11-03 | 2014-11-03 | Traditional Chinese medicine granules for preventing and treating piglet bacterial enteritis and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410608124.8A CN104367670A (en) | 2014-11-03 | 2014-11-03 | Traditional Chinese medicine granules for preventing and treating piglet bacterial enteritis and preparation method thereof |
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| CN104367670A true CN104367670A (en) | 2015-02-25 |
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| CN201410608124.8A Pending CN104367670A (en) | 2014-11-03 | 2014-11-03 | Traditional Chinese medicine granules for preventing and treating piglet bacterial enteritis and preparation method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106421734A (en) * | 2016-12-14 | 2017-02-22 | 合肥和源农业科技有限公司 | Chinese herbal medicine for preventing and treating pig viral enteritis |
| CN114159502A (en) * | 2021-11-01 | 2022-03-11 | 齐鲁工业大学 | Anti-diarrhea traditional Chinese medicine composition fermented by bacillus cereus, preparation method and application |
-
2014
- 2014-11-03 CN CN201410608124.8A patent/CN104367670A/en active Pending
Non-Patent Citations (2)
| Title |
|---|
| 张元新: "一例猪细菌性肠炎的治疗体会", 《北方牧业》 * |
| 旷惠桃等: "《中医本草疗法（珍藏本）超值版》", 31 August 2012, 湖南科学技术出版社 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106421734A (en) * | 2016-12-14 | 2017-02-22 | 合肥和源农业科技有限公司 | Chinese herbal medicine for preventing and treating pig viral enteritis |
| CN114159502A (en) * | 2021-11-01 | 2022-03-11 | 齐鲁工业大学 | Anti-diarrhea traditional Chinese medicine composition fermented by bacillus cereus, preparation method and application |
| CN114159502B (en) * | 2021-11-01 | 2022-11-08 | 齐鲁工业大学 | Anti-diarrhea traditional Chinese medicine composition fermented by bacillus cereus, preparation method and application |
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Application publication date: 20150225 |