CN102091151B - Traditional medicinal composition with wind-dispelling and dampness-removing function and preparation method thereof - Google Patents

Traditional medicinal composition with wind-dispelling and dampness-removing function and preparation method thereof Download PDF

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Publication number
CN102091151B
CN102091151B CN2009102291975A CN200910229197A CN102091151B CN 102091151 B CN102091151 B CN 102091151B CN 2009102291975 A CN2009102291975 A CN 2009102291975A CN 200910229197 A CN200910229197 A CN 200910229197A CN 102091151 B CN102091151 B CN 102091151B
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radix
parts
rhizoma
root
synergist
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CN102091151A (en
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陈庆忠
王斌
安同伟
赵娈
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TIANJIN ZHONGGAO BIOTECHNOLOGY CO Ltd
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TIANJIN ZHONGGAO BIOTECHNOLOGY CO Ltd
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Abstract

The invention relates to a traditional medicinal composition with wind-dispelling and dampness-removing function. The traditional medicinal composition comprises fineleaf schizonepeta herb, divaricate saposhnikovia root, incised notopterygium rhizome, heracleum, bupleurum, hogfennel root, bitter orange, Indian buead, platycodon root, szechuan lovage rhizome, liquoric root, mint, amikacin, aminophylline, bismuth subnitrate, a control release agent and a synergist. A preparation method of the traditional medicinal composition comprises the following steps of: weighing the fineleaf schizonepeta herb, the divaricate saposhnikovia root, the incised notopterygium rhizome, the heracleum, the bupleurum, the hogfennel root, the bitter orange, the Indian buead, the platycodon root, the szechuan lovage rhizome, the liquoric root and the mint according to the weight ratio respectively, grinding the materials into powder, sieving the powder through a 80-mesh sieve and mixing the power to obtain a mixture A; and (2) weighing the amikacin, the aminophylline, the bismuth subnitrate, the control release agent and the synergist according to the weight ratio respectively, adding the materials into the mixture A to mix uniformly. The traditional medicinal composition has the effects of clearing heat and releasing toxin, dispelling wind and removing dampness, and resolving the exterior with warmthand acridity, is convenient to use, and has no toxic or side effect, no medicinal residues, low cost and no medicament resistance.

Description

Has Chinese medicine composition of dispelling wind damp eliminating function and preparation method thereof
Technical field
The invention belongs to poultry and use field of veterinary, especially a kind of Chinese medicine composition and preparation method thereof with dispelling wind damp eliminating function.
Background technology
Traditional Chinese veterinary medicine is thought: the animal viral respiratory tract disease, and the disease appearing in blood system and edema caused by disorder of QI, intenseness of heat is gone into blood, the absurd row of forcing blood, internal organs are hemorrhage; Excessive noxious heat, the cloudy Tianjin of burning, thirst and liking drink; Heat attacking the pericardium, the stagnation of phlegm envelope is so see nervous symptoms; Enteral becomes under scorching urgent Tianjin, so see loose stool.We's QI and blood is two clear, is the optimal treatment means.Modern traditional Chinese veterinary medicine research shows: originally can heat-clearing and toxic substances removing, and eliminating phlegm and relieving asthma, antibiotic diuresis improves hemogram and changes, and removes morbid poison in the blood, human body immunity improving power.Pathomorphology also shows: the effect that we have the protection internal organs, alleviate pathological lesion.Scale, intensive culture and the world constantly integrate with; The drug residue problem of export enterprise also constantly occurs; In order better to control the drug residue problem, the bonded powder composite of Chinese and western drugs can be avoided the appearance of drug residue, can be good at improving present situation.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine composition with dispelling wind damp eliminating function; This Chinese medicine composition has heat-clearing and toxic substances removing, dispelling wind damp eliminating, relieving the exterior syndrome with drugs of pungent in flavor and warm in nature effect, has no side effect, and drug residue can not take place; Easy to use, cost is lower and have no drug resistance.
Another object of the present invention is to provide a kind of method for preparing with Chinese medicine composition of dispelling wind damp eliminating function.
The present invention solves its technical problem and realizes through following technical scheme:
A kind of Chinese medicine composition with dispelling wind damp eliminating function, its Chinese medicinal composition and ratio of weight and number thereof are respectively:
Herba Schizonepetae 1-2 part; Windproof 1-2 part;
Rhizoma Et Radix Notopterygii 1-2 part; Radix Angelicae Pubescentis 1-2 part;
Radix Bupleuri 1-2 part; Radix Peucedani 1-2 part;
Fructus Aurantii 1-2 part; Poria 1-2 part;
Radix Platycodonis 1-2 part; Rhizoma Chuanxiong 1-2 part;
Radix Glycyrrhizae 1-2 part; Herba Menthae 1-2 part;
Amikacin 1-2 part; Aminophylline 0.5-1.5 part;
Bismuth subnitrate 1-1.5 part; Release control agent 10-20 part;
Synergist 40-50 part.
And this Chinese medicinal composition and optimum ratio of weight and number thereof are respectively:
2 parts of Herba Schizonepetae; Windproof 2 parts;
2 parts of Rhizoma Et Radix Notopterygiis; 2 parts of Radix Angelicae Pubescentiss;
2 parts of Radix Bupleuri; 2 parts of Radix Peucedanis;
2 parts of Fructus Aurantiis; 2 parts in Poria;
2 parts of Radix Platycodoniss; 2 parts of Rhizoma Chuanxiongs;
2 parts in Radix Glycyrrhizae; 2 parts of Herba Menthaes;
2 parts of amikacins; 1 part of aminophylline;
1.2 parts of bismuth subnitrates; Release 12.5 parts of control agent;
45.3 parts of synergists.
And, described release the control agent be hydroxypropyl emthylcellulose, synergist is a trimethoprim.
A kind of method for preparing with Chinese medicine composition of dispelling wind damp eliminating function, the step of its preparation method is:
(1) take by weighing Herba Schizonepetae, windproof, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Radix Bupleuri, Radix Peucedani, Fructus Aurantii, Poria, Radix Platycodonis, Rhizoma Chuanxiong, Radix Glycyrrhizae, Herba Menthae powder respectively according to ratio of weight and number and be broken into powder, and all through 80 mesh sieves;
(2) with the Herba Schizonepetae behind the crushing screening, windproof, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Radix Bupleuri, Radix Peucedani, Fructus Aurantii, Poria, Radix Platycodonis, Rhizoma Chuanxiong, Radix Glycyrrhizae, Herba Menthae uniform mixing, obtain mixture A;
(3) take by weighing amikacin, aminophylline, bismuth subnitrate respectively, release and control mix homogeneously among agent, the synergist adding mixture A according to ratio of weight and number, promptly obtain the Chinese medicine composition that finished product has dispelling wind damp eliminating function.
Advantage of the present invention and beneficial effect are:
1, effective ingredient can effectively be killed pathogenic microorganism in this Chinese medicine composition; Effective ingredient combines maximum performance synergism; The disease that present antibacterial and virus mixed infection are caused has better curative effect; And can effectively bring down a fever, antiinflammatory, human body immunity improving power, make body possess resistance against diseases, cure rate is higher.
2, this Chinese medicine composition broad-spectrum high efficacy promotes gastrointestinal secretion and wriggling, helps enterotoxin and discharges; Simultaneously, just can reach the blood peak concentration of drug at extremely low concentration and in the short period.
3, the present invention has heat-clearing and toxic substances removing, dispelling wind damp eliminating, relieving the exterior syndrome with drugs of pungent in flavor and warm in nature effect, has no side effect, and drug residue can not take place, and is easy to use, and cost is lower and have no drug resistance.
The specific embodiment
The present invention further details through following examples.Need to prove: following embodiment is illustrative, is not determinate, can not limit protection scope of the present invention with following embodiment.
Herba Schizonepetae involved in the present invention, windproof, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Radix Bupleuri, Radix Peucedani, Fructus Aurantii, Poria, Radix Platycodonis, Rhizoma Chuanxiong, Radix Glycyrrhizae, Herba Menthae, amikacin, aminophylline, bismuth subnitrate, release the control agent, synergist all can be bought on market and obtain.
Embodiment 1
A kind of Chinese medicine composition with dispelling wind damp eliminating function, its Chinese medicinal composition and weight thereof are respectively: Herba Schizonepetae 10g, windproof 10g, Rhizoma Et Radix Notopterygii 10g, Radix Angelicae Pubescentis 10g, Radix Bupleuri 10g, Radix Peucedani 10g, Fructus Aurantii 10g, Poria 10g, Radix Platycodonis 10g, Rhizoma Chuanxiong 10g, Radix Glycyrrhizae 10g, Herba Menthae 10g, amikacin 10g, aminophylline 15g, bismuth subnitrate 15g, release control agent 100g, synergist 400g; Releasing the control agent is hydroxypropyl emthylcellulose, and synergist is a trimethoprim.
A kind of method for preparing with Chinese medicine composition of dispelling wind damp eliminating function, the step of its preparation method is:
(1) take by weighing Herba Schizonepetae, windproof, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Radix Bupleuri, Radix Peucedani, Fructus Aurantii, Poria, Radix Platycodonis, Rhizoma Chuanxiong, Radix Glycyrrhizae, Herba Menthae powder respectively according to ratio of weight and number and be broken into powder, and all through 80 mesh sieves;
(2) with the Herba Schizonepetae behind the crushing screening, windproof, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Radix Bupleuri, Radix Peucedani, Fructus Aurantii, Poria, Radix Platycodonis, Rhizoma Chuanxiong, Radix Glycyrrhizae, Herba Menthae uniform mixing, obtain mixture A;
(3) take by weighing amikacin, aminophylline, bismuth subnitrate respectively, release and control mix homogeneously among agent, the synergist adding mixture A according to ratio of weight and number, promptly obtain the Chinese medicine composition that finished product has dispelling wind damp eliminating function.
Embodiment 2
A kind of Chinese medicine composition with dispelling wind damp eliminating function, its Chinese medicinal composition and weight thereof are respectively: Herba Schizonepetae 20g, windproof 20g, Rhizoma Et Radix Notopterygii 20g, Radix Angelicae Pubescentis 20g, Radix Bupleuri 20g, Radix Peucedani 20g, Fructus Aurantii 20g, Poria 20g, Radix Platycodonis 20g, Rhizoma Chuanxiong 20g, Radix Glycyrrhizae 20g, Herba Menthae 20g, amikacin 20g, aminophylline 10g, bismuth subnitrate 12g, hydroxypropyl emthylcellulose 125g, trimethoprim 453g.
The step of its preparation method is with embodiment 1.
Embodiment 3
A kind of Chinese medicine composition with dispelling wind damp eliminating function, its Chinese medicinal composition and weight thereof are respectively: Herba Schizonepetae 15g, windproof 15g, Rhizoma Et Radix Notopterygii 15g, Radix Angelicae Pubescentis 15g, Radix Bupleuri 15g, Radix Peucedani 15g, Fructus Aurantii 15g, Poria 15g, Radix Platycodonis 15g, Rhizoma Chuanxiong 15g, Radix Glycyrrhizae 15g, Herba Menthae 15g, amikacin 15g, aminophylline 5g, bismuth subnitrate 12g, hydroxypropyl emthylcellulose 150g, trimethoprim 500g.
The step of its preparation method is with embodiment 1.
Method for using of the present invention:
Prevention: poultry, fowl all restrain by per kilogram of body weight 0.5, or add the dosage that these article 500 restrain by the per 100 kilograms of feedstuffs of the material feeding amount of every day, and poultry adds in the whole day forage volume; Fowl adds in whole day 1/5th forage volumes once to be fed, and 1 day 1 time, logotype 3 days;
Treatment: add 1 times of use by preventive dose.
Health care: circle is expanded young crowd in (1), health care when turn-taking, and uses by preventive dose, 1 day 1 time, logotype 2-3 days, prevents because virus and the bacterial respiratory tract disease that environmental change causes; (2) when weather changes, health care when particularly the gentle relaxing the bowels with purgatives of warm nature of strong wind falls is used by preventive dose, and 1 day 1 time, logotype 2-3 days.Prevent the generation of above-mentioned disease.
Use advantage of the present invention through concrete description of test below:
The present invention is to bacteriostatic test in the animality experimental chicken escherichia coli body:
1,35 age in days Ai Weiyin chickens are 200, random packet, 50 every group, totally four groups.Be prevention group of the present invention, treatment group of the present invention, pure Chinese medicine matched group, blank control group.
2, strain is bought by China Veterinery Drug Inspection Office, inoculates in proportion, dilution, packing, sealing, preservation.
3, prevention group of the present invention is by the administration of preventive dose batch mixing, and logotype is drug withdrawal two days later, and every subcutaneous injection strain 0.3ml then only all press 0.3ml/ to other three groups, and the subcutaneous injection administration is pathogenic.Inoculate and treat after 2 hours, dosage for treatment group of the present invention and pure treatment by Chinese herbs group all by the therapeutic dose administration, logotype drug withdrawal in three days is observed two days later, the not administration of blank group was observed four to five days.Result such as following table:
The example number Prevention group of the present invention Treatment group of the present invention Pure treatment by Chinese herbs group The blank group
The inoculation number 50 50 50 50
Cure number 43 41 34 3
Death toll 2 3 6 36
Survival rate 96% 94% 88% 28%
But by last table knowledge capital invention prevention group medication drug withdrawal after three days, have 2 to take place deadly behind the injection bacterium liquid, survive 43, prevent protective rate 96%, and dead 36 of blank group has only 28% survival rate, two groups relatively differ highly significant.Preventive effect very the ideal of the present invention to chicken AC is described; Treatment of the present invention is organized dead 1, survival rate 96%, and the cure rate of pure treatment by Chinese herbs group is 76%, the therapeutic effect that treatment group of the present invention is described is apparently higher than pure treatment by Chinese herbs group.
4, to the treatment of contagious catarrh
The AA of Baoding plant broiler chicken, 37 ages in days, 14000, divide A, two hen houses of B, A the full crowd of hen house sickness rate reaches on 94%, and B the full crowd of hen house sickness rate reaches on 89%, and death has appearred in indivedual chickens.Its jumpbogroup characteristics are: morbidity chicken crowd has obvious respiratory symptom, indivedual chickens row's greens or yellow green, yellow-white loose stool, and the chicken crowd mental status and feed intake are normal, along with feed intake minimizing, phenomenon such as listless constantly appear in PD.Dissect symptom: larynx mucosa secretions increase appears in jumpbogroup, even cheesy block of secretion is arranged wherein, and the lymphonodi duodenales enlargement is hemorrhage individually, has a small amount of chicken the enteric hemorrhage phenomenon to occur.Therapeutic Method is: the therapeutic dose administration, cooperate the multidimensional electropolishing treatment, and improve the warming environment that waits of coop ventilation.
The example number A hen house B hen house
The treatment number ?6000 ?8000
Cure number ?5943 ?7960
Death toll ?57 ?40
Cure rate ?99.1% ?99.5%
Can be learnt that by last table this invention has very high cure rate to contagious catarrh and complication thereof, the present invention has good antidiarrheal, antibacterial, improves the intestinal environment function chicken crowd enteritis, diarrhea.The enteritis, diarrhea that the chicken parasitic disease is caused also has excellent curative.

Claims (3)

1. Chinese medicine composition with dispelling wind damp eliminating function, it is characterized in that: this Chinese medicinal composition and ratio of weight and number thereof are respectively:
Herba Schizonepetae 1-2 part; Windproof 1-2 part;
Rhizoma Et Radix Notopterygii 1-2 part; Radix Angelicae Pubescentis 1-2 part;
Radix Bupleuri 1-2 part; Radix Peucedani 1-2 part;
Fructus Aurantii 1-2 part; Poria 1-2 part;
Radix Platycodonis 1-2 part; Rhizoma Chuanxiong 1-2 part;
Radix Glycyrrhizae 1-2 part; Herba Menthae 1-2 part;
Amikacin 1-2 part; Aminophylline 0.5-1.5 part;
Bismuth subnitrate 1-1.5 part; Release control agent 10-20 part;
Synergist 40-50 part; Releasing the control agent is hydroxypropyl emthylcellulose, and synergist is a trimethoprim.
2. the Chinese medicine composition with dispelling wind damp eliminating function according to claim 1 is characterized in that: this Chinese medicinal composition and ratio of weight and number thereof are respectively:
2 parts of Herba Schizonepetae; Windproof 2 parts;
2 parts of Rhizoma Et Radix Notopterygiis; 2 parts of Radix Angelicae Pubescentiss;
2 parts of Radix Bupleuri; 2 parts of Radix Peucedanis;
2 parts of Fructus Aurantiis; 2 parts in Poria;
2 parts of Radix Platycodoniss; 2 parts of Rhizoma Chuanxiongs;
2 parts in Radix Glycyrrhizae; 2 parts of Herba Menthaes;
2 parts of amikacins; 1 part of aminophylline;
1.2 parts of bismuth subnitrates; Release 12.5 parts of control agent;
45.3 parts of synergists; Releasing the control agent is hydroxypropyl emthylcellulose, and synergist is a trimethoprim.
3. method for preparing with Chinese medicine composition of dispelling wind damp eliminating function as claimed in claim 1, it is characterized in that: the step of this method for preparing is:
(1) take by weighing Herba Schizonepetae, windproof, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Radix Bupleuri, Radix Peucedani, Fructus Aurantii, Poria, Radix Platycodonis, Rhizoma Chuanxiong, Radix Glycyrrhizae, Herba Menthae powder respectively according to ratio of weight and number and be broken into powder, and all through 80 mesh sieves;
(2) with the Herba Schizonepetae behind the crushing screening, windproof, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Radix Bupleuri, Radix Peucedani, Fructus Aurantii, Poria, Radix Platycodonis, Rhizoma Chuanxiong, Radix Glycyrrhizae, Herba Menthae uniform mixing, obtain mixture A;
(3) take by weighing amikacin, aminophylline, bismuth subnitrate respectively, release and control mix homogeneously among agent, the synergist adding mixture A according to ratio of weight and number; Releasing the control agent is hydroxypropyl emthylcellulose; Synergist is a trimethoprim, promptly obtains the Chinese medicine composition that finished product has dispelling wind damp eliminating function.
CN2009102291975A 2009-12-15 2009-12-15 Traditional medicinal composition with wind-dispelling and dampness-removing function and preparation method thereof Expired - Fee Related CN102091151B (en)

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CN103006856A (en) * 2013-01-02 2013-04-03 李承平 Radix bupleuri composite cold capsules
CN103372161A (en) * 2013-07-16 2013-10-30 彭安泽 Medicament for treating bad cold
CN103734507B (en) * 2013-12-12 2015-06-24 徐茂航 Fermentation preparation method of laying hen feed
CN104606326A (en) * 2015-01-30 2015-05-13 苏州市天灵中药饮片有限公司 Traditional Chinese medicine buccal tablets for preventing cold and preparation method thereof
CN107927367A (en) * 2017-12-04 2018-04-20 贵州九鼎生物科技有限公司 Ecological sheep feed and preparation method thereof
CN114146121A (en) * 2020-09-08 2022-03-08 鲁南制药集团股份有限公司 Application of traditional Chinese medicine composition in preparation of medicine for treating dyspepsia

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