CN104825700A - Traditional Chinese medicine composition for resisting bacteria and diminishing inflammation - Google Patents

Traditional Chinese medicine composition for resisting bacteria and diminishing inflammation Download PDF

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Publication number
CN104825700A
CN104825700A CN201510267273.7A CN201510267273A CN104825700A CN 104825700 A CN104825700 A CN 104825700A CN 201510267273 A CN201510267273 A CN 201510267273A CN 104825700 A CN104825700 A CN 104825700A
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China
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parts
extract
chinese medicine
medicine composition
filtrate
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Pending
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CN201510267273.7A
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Chinese (zh)
Inventor
徐再
徐凯
赵维达
赵云龙
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Five Lakes New Material Technology Development Corp Ltd Of Zhangjagang City
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Five Lakes New Material Technology Development Corp Ltd Of Zhangjagang City
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Priority to CN201510267273.7A priority Critical patent/CN104825700A/en
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Abstract

The invention relates to the technical field of veterinary medicines, and particularly relates to a traditional Chinese medicine composition for resisting bacteria and diminishing inflammation. The traditional Chinese medicine composition comprises the following raw materials in parts by mass: 15-45 parts of rheum officinale, 16-28 parts of a dandelion extract, 15-45 parts of mint, 2-8 parts of common andrographis herb, 6-15 parts of a felwort extract, 4-15 parts of borneol, 3-8 parts of aloe normal juice, 2-6 parts of a willow bark extract, 4-10 parts of pine needle meal, 0.8-2.8 parts of normal saline, 0.2-0.8 parts of a chloridion neutralizer and 0.1-0.3 parts of a heavy metal chelating agent. The traditional Chinese medicine composition has the following beneficial effects: 1. the dandelion extract is added, and used together with mint and the felwort extract, and thus the effects of resisting bacteria and diminishing inflammation of the traditional Chinese medicine composition are improved, and the dandelion extract is used for the composition for resisting bacteria and diminishing inflammation, and thus the cost is low and the efficacy is obvious; 2. the willow bark extract is added and compounded with the dandelion extract, so that the remarkable advantages of resisting bacteria and diminishing inflammation are provided, the respiratory tract and reproductive disorder diseases of animals can also be effectively prevented, and the composition is high in palatability, and is capable of improving the appetites of the animals, natural, and free from medicine resistance and toxic or side effects.

Description

A kind of Chinese medicine composition of anti-inflammation
Technical field
The present invention relates to veterinary drug technical field, especially a kind of Chinese medicine composition of anti-inflammation.
Background technology
Anti-inflammation therapy is the feature of the cause of disease for inflammation and pathological change process, and application antibacterial-anti-inflammatory drug eliminates pro-inflammatory cytokine, the symptom that reduces inflammation, the remedy measures that prevents inflammation from further developing.Along with the development of aquaculture, the approach that poultry catches becomes increasingly complex, with disease of alimentary tract of livestock husbandry and birds and respiratory system disease the most common, the current key agents being used for the treatment of such disease is antibiotics.But the antibiotic abuse in cultivation market has caused antibacterial at present, virus produces drug resistance, to such an extent as to propagates between the kind of initiation epidemic disease, affects the foreign trade of animal products and the health of eater.
Because current diseases of bird and livestock mostly is mixed infection or secondary infection, single use antibiotic therapy can not reach desirable curative effect.The conventional treatments adopted above-mentioned disease uses heavy dose of broad-spectrum antibiotic drug, this kind of medicine, although sterilization speed is fast, antibacterial easily develops immunity to drugs, and it is flourish to intersect sense, causes the result of use degradation of broad-spectrum antibiotic drug.
Summary of the invention
The technical problem to be solved in the present invention is: overcome deficiency of the prior art, provides a kind of result of use good, has a broad antifungal spectrum, the important composition of medication anti-inflammation easily.
For solving the problems of the technologies described above, the technical solution used in the present invention is as follows:
A Chinese medicine composition for anti-inflammation, the mass parts of described Chinese medicine composition is composed as follows: Radix Et Rhizoma Rhei 15-45 part, Herba Taraxaci extract 16-28 part, Herba Menthae 15-45 part, Herba Andrographis 2-8 part, Radix Gentianae extract 6-15 part, Borneolum Syntheticum 4-15 part, Aloe original juice 3-8 part, extract of willow bark 2-6 part, pine needle powder 4-10 part, normal saline 0.8-2.8 part; Chloride ion nertralizer 0.2-0.8 part, heavy metal chelant 0.1-0.3 part.
Further, described Radix Et Rhizoma Rhei, Herba Menthae, Herba Andrographis are traditional Chinese medicinal extract powder.
Further, the preparation method of described traditional Chinese medicinal extract powder is as follows:
(1) get Radix Et Rhizoma Rhei 15-45 part, Herba Menthae 15-45 part, Herba Andrographis 2-8 part, chopping, is placed in 40% ethanol and extracts, and after extracting 24h, filter to get filtrate A, collects filtering residue;
(2) ethanol filtering residue collected in step (1) being placed in 40% extracts, and after extracting 24h, filter to get filtrate B;
(3) mix centrifugal by filtrate A and liquor B, get supernatant, reclaiming ethanol is 4.6-5.2:1 to medicine liquid volume and medical material weight ratio, obtains traditional Chinese medicinal extract powder after spraying dry.
Further, the extracting method that described Herba Taraxaci extract adopts is: pulverized by Herba Taraxaci, then with 95% ethanol carry out immersions 24h after, filtration, filtrate obtains Herba Taraxaci extract after concentrating.
Further, the method that described extract of willow bark adopts adds 10 times of water gagings by loading in extraction pot after bark of willow truncate, and boil 3 hours, steam pressure is 1MPa process, filters, obtain the first filtrate and filtering residue; Filtering residue adds 6 times of water gagings again, boils 1.5 hours, and steam pressure is 1MPa process, filters, and obtains the second filtrate and filtering residue respectively; Filtering residue discards; By the first filtrate, the second filtrate mixes and is concentrated into D is that namely 1.23-1.25 obtains extract extractum.
Further, sodium thiosulfate selected by described chloride ion nertralizer.
Further, described heavy metal chelant selects disodiumedetate.
Further, the mass parts of described Chinese medicine composition is composed as follows: Radix Et Rhizoma Rhei 30 parts, Herba Taraxaci extract 20 parts, Herba Menthae 30 parts, Herba Andrographis 5 parts, Radix Gentianae extract 10 parts, Borneolum Syntheticum 10 parts, Aloe original juice 5 parts, extract of willow bark 4 parts, pine needle powder 7 parts, normal saline 1.8 parts; Chloride ion nertralizer 0.5 part, heavy metal chelant 0.2 part.
Further, described Chinese medicine composition is capsule.
The beneficial effect of technical scheme of the present invention is adopted to be:
1, with the addition of Herba Taraxaci extract in the present invention, use together with Herba Menthae, Radix Gentianae extract, improve the anti-inflammation effect of Chinese medicine composition, in the present invention, Herba Taraxaci extract is used for anti-inflammation compositions, expand the medicinal scope of Herba Taraxaci extract, and with low cost, drug effect is obvious;
2, with the addition of extract of willow bark in the present invention, use composite with Herba Taraxaci extract, there is significant anti-inflammation advantage, effectively can also prevent animal respiratory, breeding difficulty disease, palatability is strong, can promote the appetite of animal, natural, have no drug resistance, have no side effect.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention will be further described.
A Chinese medicine composition for anti-inflammation, the mass parts of described Chinese medicine composition is composed as follows: Radix Et Rhizoma Rhei 15-45 part, Herba Taraxaci extract 16-28 part, Herba Menthae 15-45 part, Herba Andrographis 2-8 part, Radix Gentianae extract 6-15 part, Borneolum Syntheticum 4-15 part, Aloe original juice 3-8 part, extract of willow bark 2-6 part, pine needle powder 4-10 part, normal saline 0.8-2.8 part; Chloride ion nertralizer 0.2-0.8 part, heavy metal chelant 0.1-0.3 part.
Wherein, described Radix Et Rhizoma Rhei, Herba Menthae, Herba Andrographis are traditional Chinese medicinal extract powder.
Wherein, the preparation method of described traditional Chinese medicinal extract powder is as follows:
(1) get Radix Et Rhizoma Rhei 15-45 part, Herba Menthae 15-45 part, Herba Andrographis 2-8 part, chopping, is placed in 40% ethanol and extracts, and after extracting 24h, filter to get filtrate A, collects filtering residue;
(2) ethanol filtering residue collected in step (1) being placed in 40% extracts, and after extracting 24h, filter to get filtrate B;
(3) mix centrifugal by filtrate A and liquor B, get supernatant, reclaiming ethanol is 4.6-5.2:1 to medicine liquid volume and medical material weight ratio, obtains traditional Chinese medicinal extract powder after spraying dry.
Wherein, the extracting method that described Herba Taraxaci extract adopts is: pulverized by Herba Taraxaci, then with 95% ethanol carry out immersions 24h after, filtration, filtrate obtains Herba Taraxaci extract after concentrating.
Wherein, the method that described extract of willow bark adopts adds 10 times of water gagings by loading in extraction pot after bark of willow truncate, and boil 3 hours, steam pressure is 1MPa process, filters, obtain the first filtrate and filtering residue; Filtering residue adds 6 times of water gagings again, boils 1.5 hours, and steam pressure is 1MPa process, filters, and obtains the second filtrate and filtering residue respectively; Filtering residue discards; By the first filtrate, the second filtrate mixes and is concentrated into D is that namely 1.23-1.25 obtains extract extractum.
Wherein, sodium thiosulfate selected by described chloride ion nertralizer.
Wherein, described heavy metal chelant selects disodiumedetate.
The raw material composition of embodiment 1-6 and data are in table 1.
Embodiment 3 is preferred forms.
Application test example:
1, experimental animal
Get the chickling that 300 growing ways are close, after feeding 14 days with complete feed, randomly draw wherein 60 as a control group, other 240 are divided into 6 groups of test group at random, are denoted as 1 group, 2 groups, 3 groups, 4 groups, 5 groups, 6 groups respectively; Inject 1.0 hundred million escherichia coli respectively to got 300 chickens, do not take remedy measures after matched group inoculation, test group 1-6 group is fed Chinese medicine composition obtained in embodiment 1-6 respectively, feeds continuously 5 days, observation therapeutic effect.
Although above-described embodiment describes in detail technical scheme of the present invention, but technical scheme of the present invention is not limited to above embodiment, when not departing from thought of the present invention and aim, claims limited range of the present invention all will be fallen into any change that technical scheme of the present invention is done.

Claims (9)

1. a Chinese medicine composition for anti-inflammation, is characterized in that the mass parts of described Chinese medicine composition is composed as follows: Radix Et Rhizoma Rhei 15-45 part, Herba Taraxaci extract 16-28 part, Herba Menthae 15-45 part, Herba Andrographis 2-8 part, Radix Gentianae extract 6-15 part, Borneolum Syntheticum 4-15 part, Aloe original juice 3-8 part, extract of willow bark 2-6 part, pine needle powder 4-10 part, normal saline 0.8-2.8 part; Chloride ion nertralizer 0.2-0.8 part, heavy metal chelant 0.1-0.3 part.
2. the Chinese medicine composition of a kind of anti-inflammation according to claim 1, is characterized in that: described Radix Et Rhizoma Rhei, Herba Menthae, Herba Andrographis are traditional Chinese medicinal extract powder.
3. the Chinese medicine composition of a kind of anti-inflammation according to claim 2, is characterized in that the preparation method of described traditional Chinese medicinal extract powder is as follows:
(1) get Radix Et Rhizoma Rhei 15-45 part, Herba Menthae 15-45 part, Herba Andrographis 2-8 part, chopping, is placed in 40% ethanol and extracts, and after extracting 24h, filter to get filtrate A, collects filtering residue;
(2) ethanol filtering residue collected in step (1) being placed in 40% extracts, and after extracting 24h, filter to get filtrate B;
(3) mix centrifugal by filtrate A and liquor B, get supernatant, reclaiming ethanol is 4.6-5.2:1 to medicine liquid volume and medical material weight ratio, obtains traditional Chinese medicinal extract powder after spraying dry.
4. the Chinese medicine composition of a kind of anti-inflammation according to claim 1, it is characterized in that the extracting method that described Herba Taraxaci extract adopts is: pulverized by Herba Taraxaci, then with 95% ethanol carry out immersion 24h after, filter, after filtrate is concentrated, obtain Herba Taraxaci extract.
5. the Chinese medicine composition of a kind of anti-inflammation according to claim 1, it is characterized in that the method that described extract of willow bark adopts adds 10 times of water gagings by loading in extraction pot after bark of willow truncate, boil 3 hours, steam pressure is 1MPa process, filter, obtain the first filtrate and filtering residue; Filtering residue adds 6 times of water gagings again, boils 1.5 hours, and steam pressure is 1MPa process, filters, and obtains the second filtrate and filtering residue respectively; Filtering residue discards; By the first filtrate, the second filtrate mixes and is concentrated into D is that namely 1.23-1.25 obtains extract extractum.
6. the Chinese medicine composition of a kind of anti-inflammation according to claim 1, is characterized in that: sodium thiosulfate selected by described chloride ion nertralizer.
7. the Chinese medicine composition of a kind of anti-inflammation according to claim 1, is characterized in that: described heavy metal chelant selects disodiumedetate.
8. the Chinese medicine composition of a kind of anti-inflammation according to claim 1, is characterized in that the mass parts of described Chinese medicine composition is composed as follows: Radix Et Rhizoma Rhei 30 parts, Herba Taraxaci extract 20 parts, Herba Menthae 30 parts, Herba Andrographis 5 parts, Radix Gentianae extract 10 parts, Borneolum Syntheticum 10 parts, Aloe original juice 5 parts, extract of willow bark 4 parts, pine needle powder 7 parts, normal saline 1.8 parts; Chloride ion nertralizer 0.5 part, heavy metal chelant 0.2 part.
9. the Chinese medicine composition of a kind of anti-inflammation according to any one of claim 1-8, is characterized in that: described Chinese medicine composition is capsule.
CN201510267273.7A 2015-05-23 2015-05-23 Traditional Chinese medicine composition for resisting bacteria and diminishing inflammation Pending CN104825700A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104489329A (en) * 2014-12-14 2015-04-08 河南联合英伟饲料有限公司 Drug-core type feed particle for resisting canine bacterial diseases and preparation method thereof
CN105748764A (en) * 2016-03-12 2016-07-13 华北理工大学 Traditional Chinese medicine composition with antibacterial and anti-inflammation effects and preparation method of composition
CN107714898A (en) * 2017-10-27 2018-02-23 尼玛才让 Intestines spirit is led in domestic animal expelling parasite clearing lung-heat

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102038881A (en) * 2010-12-17 2011-05-04 天津康莱森生物科技集团有限公司 Traditional Chinese medicine composition with antibacterial and antiphlogistic effect
CN102771634A (en) * 2011-05-10 2012-11-14 李得光 Health-care feed for poultry
CN102845654A (en) * 2012-10-16 2013-01-02 青岛田瑞生态科技有限公司 Manufacture method of feed capable of preventing and controlling chicken cholera
CN103800502A (en) * 2012-11-12 2014-05-21 青岛康地恩动物药业有限公司 Powder for treatment of chicken colibacillosis and preparation method thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102038881A (en) * 2010-12-17 2011-05-04 天津康莱森生物科技集团有限公司 Traditional Chinese medicine composition with antibacterial and antiphlogistic effect
CN102771634A (en) * 2011-05-10 2012-11-14 李得光 Health-care feed for poultry
CN102845654A (en) * 2012-10-16 2013-01-02 青岛田瑞生态科技有限公司 Manufacture method of feed capable of preventing and controlling chicken cholera
CN103800502A (en) * 2012-11-12 2014-05-21 青岛康地恩动物药业有限公司 Powder for treatment of chicken colibacillosis and preparation method thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104489329A (en) * 2014-12-14 2015-04-08 河南联合英伟饲料有限公司 Drug-core type feed particle for resisting canine bacterial diseases and preparation method thereof
CN105748764A (en) * 2016-03-12 2016-07-13 华北理工大学 Traditional Chinese medicine composition with antibacterial and anti-inflammation effects and preparation method of composition
CN107714898A (en) * 2017-10-27 2018-02-23 尼玛才让 Intestines spirit is led in domestic animal expelling parasite clearing lung-heat

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Application publication date: 20150812