CN104873621A - Antibacterial and anti-inflammation traditional Chinese medicine composition - Google Patents
Antibacterial and anti-inflammation traditional Chinese medicine composition Download PDFInfo
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- CN104873621A CN104873621A CN201510273724.8A CN201510273724A CN104873621A CN 104873621 A CN104873621 A CN 104873621A CN 201510273724 A CN201510273724 A CN 201510273724A CN 104873621 A CN104873621 A CN 104873621A
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Abstract
The invention relates to the technical field of veterinary medicines, in particular to an antibacterial and anti-inflammation traditional Chinese medicine composition. The traditional Chinese medicine composition comprises the following components in parts by mass: 10-50 parts of rheum palmatum, 15-30 parts of lotus Leaf extract, 10-50 parts of mint, 5-20 parts of honeysuckle, 2-8 parts of andrographis paniculata, 5-30 parts of portulaca oleracea, 4-15 parts of heartleaf houttuynia herb, 2-10 parts of folium artemisiae argyi, 3-8 parts of talcum powder, 2-6 parts of willow bark extract, 3-8 parts of pine needle powder, 0.2-0.8 part of a chloride ion neutralizer and 0.1-0.3 part of a heavy metal chelating agent. The traditional Chinese medicine composition has the benefits as follows: 1, since the lotus Leaf extract is added and used together with the mint and the honeysuckle, the antibacterial and anti-inflammation effects of the traditional Chinese medicine composition are improved; the lotus Leaf extract is used for the antibacterial and anti-inflammation composition, so that the medicinal scope of the lotus Leaf extract is expanded, the cost is low and an obvious efficacy is realized; 2, since the willow bark extract is added and used together with the lotus Leaf extract, an obvious antibacterial and anti-inflammation advantage is realized, the palatability is high, the appetite of animals is enhanced, and the traditional Chinese medicine composition is natural, and has no drug resistance and no toxic or side effects.
Description
Technical field
The present invention relates to veterinary drug technical field, especially a kind of Chinese medicine composition of anti-inflammation.
Background technology
Anti-inflammation therapy is the feature of the cause of disease for inflammation and pathological change process, and application antibacterial-anti-inflammatory drug eliminates pro-inflammatory cytokine, the symptom that reduces inflammation, the remedy measures that prevents inflammation from further developing.Along with the development of aquaculture, the approach that poultry catches becomes increasingly complex, with disease of alimentary tract of livestock husbandry and birds and respiratory system disease the most common, the current key agents being used for the treatment of such disease is antibiotics.But the antibiotic abuse in cultivation market has caused antibacterial at present, virus produces drug resistance, to such an extent as to propagates between the kind of initiation epidemic disease, affects the foreign trade of animal products and the health of eater.
Because current diseases of bird and livestock mostly is mixed infection or secondary infection, single use antibiotic therapy can not reach desirable curative effect.The conventional treatments adopted above-mentioned disease uses heavy dose of broad-spectrum antibiotic drug, this kind of medicine, although sterilization speed is fast, antibacterial easily develops immunity to drugs, and it is flourish to intersect sense, causes the result of use degradation of broad-spectrum antibiotic drug.
Summary of the invention
The technical problem to be solved in the present invention is: overcome deficiency of the prior art, provides a kind of result of use good, has a broad antifungal spectrum, the important composition of medication anti-inflammation easily.
For solving the problems of the technologies described above, the technical solution used in the present invention is as follows:
A Chinese medicine composition for anti-inflammation, the mass parts of described Chinese medicine composition is composed as follows: Radix Et Rhizoma Rhei 10-50 part, Folium Nelumbinis extract 15-30 part, Herba Menthae 10-50 part, Flos Lonicerae 5-20 part, Herba Andrographis 2-8 part, Herba Portulacae 5-30 part, Herba Houttuyniae 4-15 part, Folium Artemisiae Argyi 2-10 part, Pulvis Talci 3-8 part, extract of willow bark 2-6 part, pine needle powder 3-8 part; Chloride ion nertralizer 0.2-0.8 part, heavy metal chelant 0.1-0.3 part.
Further, described Radix Et Rhizoma Rhei, Herba Menthae, Flos Lonicerae, Herba Andrographis, Herba Portulacae, Herba Houttuyniae, Folium Artemisiae Argyi are traditional Chinese medicinal extract powder.
Further, the preparation method of described traditional Chinese medicinal extract powder is as follows:
(1) get Radix Et Rhizoma Rhei 10-50 part, Herba Menthae 10-50 part, Flos Lonicerae 5-20 part, Herba Andrographis 2-8 part, Herba Portulacae 5-30 part, Herba Houttuyniae 4-15 part, Folium Artemisiae Argyi 2-10 part, chopping, is placed in 40% ethanol and extracts, and after extracting 24h, filter to get filtrate A, collects filtering residue;
(2) ethanol filtering residue collected in step (1) being placed in 40% extracts, and after extracting 24h, filter to get filtrate B;
(3) mix centrifugal by filtrate A and liquor B, get supernatant, reclaiming ethanol is 4.5-5.5:1 to medicine liquid volume and medical material weight ratio, obtains traditional Chinese medicinal extract powder after spraying dry.
Further, the extracting method that described Folium Nelumbinis extract adopts is: pulverized by Folium Nelumbinis, then with 95% ethanol carry out immersions 24h after, filtration, filtrate obtains Folium Nelumbinis extract after concentrating.
Further, the method that described extract of willow bark adopts adds 8 times of water gagings by loading in extraction pot after bark of willow truncate, and boil 2 hours, steam pressure is 1MPa process, filters, obtain the first filtrate and filtering residue; Filtering residue adds 6 times of water gagings again, boils 1 hour, and steam pressure is 1MPa process, filters, and obtains the second filtrate and filtering residue respectively; Filtering residue discards; By the first filtrate, the second filtrate mixes and is concentrated into D is that namely 1.22-1.25 obtains extract extractum.
Further, sodium thiosulfate selected by described chloride ion nertralizer.
Further, described heavy metal chelant selects disodiumedetate.
Further, the mass parts of described Chinese medicine composition is composed as follows: Radix Et Rhizoma Rhei 30 parts, Folium Nelumbinis extract 20 parts, Herba Menthae 30 parts, Flos Lonicerae 15 parts, Herba Andrographis 5 parts, Herba Portulacae 18 parts, Herba Houttuyniae 10 parts, Folium Artemisiae Argyi 6 parts, Pulvis Talci 5 parts, extract of willow bark 4 parts, pine needle powder 5 parts; Chloride ion nertralizer 0.5 part, heavy metal chelant 0.2 part.
Further, described Chinese medicine composition is capsule.
The beneficial effect of technical scheme of the present invention is adopted to be:
1, with the addition of Folium Nelumbinis extract in the present invention, use together with Herba Menthae, Flos Lonicerae, improve the anti-inflammation effect of Chinese medicine composition, Folium Nelumbinis is used for compared with Weight-lossing hypolipemic medicine with traditional, in the present invention, Folium Nelumbinis extract is used for anti-inflammation compositions, expand the medicinal scope of Folium Nelumbinis extract, and with low cost, drug effect is obvious;
2, with the addition of extract of willow bark in the present invention, use composite with Folium Nelumbinis extract, there is significant anti-inflammation advantage, effectively can also prevent animal respiratory, breeding difficulty disease, palatability is strong, can promote the appetite of animal, natural, have no drug resistance, have no side effect.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention will be further described.
A Chinese medicine composition for anti-inflammation, the mass parts of described Chinese medicine composition is composed as follows: Radix Et Rhizoma Rhei 10-50 part, Folium Nelumbinis extract 15-30 part, Herba Menthae 10-50 part, Flos Lonicerae 5-20 part, Herba Andrographis 2-8 part, Herba Portulacae 5-30 part, Herba Houttuyniae 4-15 part, Folium Artemisiae Argyi 2-10 part, Pulvis Talci 3-8 part, extract of willow bark 2-6 part, pine needle powder 3-8 part; Chloride ion nertralizer 0.2-0.8 part, heavy metal chelant 0.1-0.3 part.
Described Radix Et Rhizoma Rhei, Herba Menthae, Flos Lonicerae, Herba Andrographis, Herba Portulacae, Herba Houttuyniae, Folium Artemisiae Argyi are traditional Chinese medicinal extract powder.
The preparation method of described traditional Chinese medicinal extract powder is as follows:
(1) get Radix Et Rhizoma Rhei 10-50 part, Herba Menthae 10-50 part, Flos Lonicerae 5-20 part, Herba Andrographis 2-8 part, Herba Portulacae 5-30 part, Herba Houttuyniae 4-15 part, Folium Artemisiae Argyi 2-10 part, chopping, is placed in 40% ethanol and extracts, and after extracting 24h, filter to get filtrate A, collects filtering residue;
(2) ethanol filtering residue collected in step (1) being placed in 40% extracts, and after extracting 24h, filter to get filtrate B;
(3) mix centrifugal by filtrate A and liquor B, get supernatant, reclaiming ethanol is 4.5-5.5:1 to medicine liquid volume and medical material weight ratio, obtains traditional Chinese medicinal extract powder after spraying dry.
The extracting method that described Folium Nelumbinis extract adopts is: pulverized by Folium Nelumbinis, then with 95% ethanol carry out immersions 24h after, filtration, filtrate obtains Folium Nelumbinis extract after concentrating.
The method that described extract of willow bark adopts adds 8 times of water gagings by loading in extraction pot after bark of willow truncate, and boil 2 hours, steam pressure is 1MPa process, filters, obtain the first filtrate and filtering residue; Filtering residue adds 6 times of water gagings again, boils 1 hour, and steam pressure is 1MPa process, filters, and obtains the second filtrate and filtering residue respectively; Filtering residue discards; By the first filtrate, the second filtrate mixes and is concentrated into D is that namely 1.22-1.25 obtains extract extractum.
Sodium thiosulfate selected by described chloride ion nertralizer.
Described heavy metal chelant selects disodiumedetate.
Described Chinese medicine composition is capsule.
The raw material composition of embodiment 1-6 and data are in table 1.
Embodiment 3 is preferred forms.
Application test example:
1, experimental animal
Get the chickling that 300 growing ways are close, after feeding 14 days with complete feed, randomly draw wherein 60 as a control group, other 240 are divided into 6 groups of test group at random, are denoted as 1 group, 2 groups, 3 groups, 4 groups, 5 groups, 6 groups respectively; Inject 1.0 hundred million escherichia coli respectively to got 300 chickens, do not take remedy measures after matched group inoculation, test group 1-6 group is fed Chinese medicine composition obtained in embodiment 1-6 respectively, feeds continuously 5 days, observation therapeutic effect.
Although above-described embodiment describes in detail technical scheme of the present invention, but technical scheme of the present invention is not limited to above embodiment, when not departing from thought of the present invention and aim, claims limited range of the present invention all will be fallen into any change that technical scheme of the present invention is done.
Claims (9)
1. a Chinese medicine composition for anti-inflammation, is characterized in that the mass parts of described Chinese medicine composition is composed as follows: Radix Et Rhizoma Rhei 10-50 part, Folium Nelumbinis extract 15-30 part, Herba Menthae 10-50 part, Flos Lonicerae 5-20 part, Herba Andrographis 2-8 part, Herba Portulacae 5-30 part, Herba Houttuyniae 4-15 part, Folium Artemisiae Argyi 2-10 part, Pulvis Talci 3-8 part, extract of willow bark 2-6 part, pine needle powder 3-8 part; Chloride ion nertralizer 0.2-0.8 part, heavy metal chelant 0.1-0.3 part.
2. the Chinese medicine composition of a kind of anti-inflammation according to claim 1, is characterized in that: described Radix Et Rhizoma Rhei, Herba Menthae, Flos Lonicerae, Herba Andrographis, Herba Portulacae, Herba Houttuyniae, Folium Artemisiae Argyi are traditional Chinese medicinal extract powder.
3. the Chinese medicine composition of a kind of anti-inflammation according to claim 2, is characterized in that the preparation method of described traditional Chinese medicinal extract powder is as follows:
(1) get Radix Et Rhizoma Rhei 10-50 part, Herba Menthae 10-50 part, Flos Lonicerae 5-20 part, Herba Andrographis 2-8 part, Herba Portulacae 5-30 part, Herba Houttuyniae 4-15 part, Folium Artemisiae Argyi 2-10 part, chopping, is placed in 40% ethanol and extracts, and after extracting 24h, filter to get filtrate A, collects filtering residue;
(2) ethanol filtering residue collected in step (1) being placed in 40% extracts, and after extracting 24h, filter to get filtrate B;
(3) mix centrifugal by filtrate A and liquor B, get supernatant, reclaiming ethanol is 4.5-5.5:1 to medicine liquid volume and medical material weight ratio, obtains traditional Chinese medicinal extract powder after spraying dry.
4. the Chinese medicine composition of a kind of anti-inflammation according to claim 1, it is characterized in that the extracting method that described Folium Nelumbinis extract adopts is: pulverized by Folium Nelumbinis, then with 95% ethanol carry out immersion 24h after, filter, after filtrate is concentrated, obtain Folium Nelumbinis extract.
5. the Chinese medicine composition of a kind of anti-inflammation according to claim 1, it is characterized in that the method that described extract of willow bark adopts adds 8 times of water gagings by loading in extraction pot after bark of willow truncate, boil 2 hours, steam pressure is 1MPa process, filter, obtain the first filtrate and filtering residue; Filtering residue adds 6 times of water gagings again, boils 1 hour, and steam pressure is 1MPa process, filters, and obtains the second filtrate and filtering residue respectively; Filtering residue discards; By the first filtrate, the second filtrate mixes and is concentrated into D is that namely 1.22-1.25 obtains extract extractum.
6. the Chinese medicine composition of a kind of anti-inflammation according to claim 1, is characterized in that: sodium thiosulfate selected by described chloride ion nertralizer.
7. the Chinese medicine composition of a kind of anti-inflammation according to claim 1, is characterized in that: described heavy metal chelant selects disodiumedetate.
8. the Chinese medicine composition of a kind of anti-inflammation according to claim 1, is characterized in that the mass parts of described Chinese medicine composition is composed as follows: Radix Et Rhizoma Rhei 30 parts, Folium Nelumbinis extract 20 parts, Herba Menthae 30 parts, Flos Lonicerae 15 parts, Herba Andrographis 5 parts, Herba Portulacae 18 parts, Herba Houttuyniae 10 parts, Folium Artemisiae Argyi 6 parts, Pulvis Talci 5 parts, extract of willow bark 4 parts, pine needle powder 5 parts; Chloride ion nertralizer 0.5 part, heavy metal chelant 0.2 part.
9. the Chinese medicine composition of a kind of anti-inflammation according to any one of claim 1-8, is characterized in that: described Chinese medicine composition is capsule.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104489329A (en) * | 2014-12-14 | 2015-04-08 | 河南联合英伟饲料有限公司 | Drug-core type feed particle for resisting canine bacterial diseases and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102038881A (en) * | 2010-12-17 | 2011-05-04 | 天津康莱森生物科技集团有限公司 | Traditional Chinese medicine composition with antibacterial and antiphlogistic effect |
| KR20110050793A (en) * | 2009-11-09 | 2011-05-17 | 이화숙 | Composition for preventing and treating nose disease comprising extract of star anis and aroma oil as active ingredients |
| CN103392921A (en) * | 2013-07-19 | 2013-11-20 | 句容市科兴畜禽养殖基地 | Traditional Chinese medicinal additive composition for chicken feed for cooling in summer and application thereof |
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- 2015-05-23 CN CN201510273724.8A patent/CN104873621A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20110050793A (en) * | 2009-11-09 | 2011-05-17 | 이화숙 | Composition for preventing and treating nose disease comprising extract of star anis and aroma oil as active ingredients |
| CN102038881A (en) * | 2010-12-17 | 2011-05-04 | 天津康莱森生物科技集团有限公司 | Traditional Chinese medicine composition with antibacterial and antiphlogistic effect |
| CN103392921A (en) * | 2013-07-19 | 2013-11-20 | 句容市科兴畜禽养殖基地 | Traditional Chinese medicinal additive composition for chicken feed for cooling in summer and application thereof |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104489329A (en) * | 2014-12-14 | 2015-04-08 | 河南联合英伟饲料有限公司 | Drug-core type feed particle for resisting canine bacterial diseases and preparation method thereof |
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Application publication date: 20150902 |