CN109331079A - Veterinary Chinese medicinal composition, veterinary drug and its preparation method and application - Google Patents
Veterinary Chinese medicinal composition, veterinary drug and its preparation method and application Download PDFInfo
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- 239000000273 veterinary drug Substances 0.000 title claims abstract description 66
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- 229940079593 drug Drugs 0.000 claims abstract description 20
- 206010004016 Bacterial diarrhoea Diseases 0.000 claims abstract description 10
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/756—Phellodendron, e.g. corktree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
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- A—HUMAN NECESSITIES
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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Abstract
The present invention provides a kind of veterinary Chinese medicinal compositions, veterinary drug and its preparation method and application, are related to veterinary drug technical field, and the Chinese medicine composition is mainly made by the Chinese bulbul, the coptis, Cortex Phellodendri, the bark of ash, granatum, Poria cocos, Rhizoma Atractylodis Macrocephalae and Radix Glycyrrhizae.Wherein, the present invention is using the Chinese bulbul as monarch drug in a prescription, the coptis, Cortex Phellodendri are ministerial drug, it is again that assistant is allowed to medicine with the bark of ash, granatum, Poria cocos, Rhizoma Atractylodis Macrocephalae and Radix Glycyrrhizae, playing the obtained veterinary Chinese medicinal composition of compounding altogether by above-mentioned each bulk pharmaceutical chemicals has effects that clearing heat and detoxicating, invigorating the spleen to dry, inducing astrigency antidiarrheal, and then the problem of alleviate existing livestock-raising field calf bacterial diarrhea well.
Description
Technical field
The present invention relates to veterinary drug technical fields, more particularly, to a kind of veterinary Chinese medicinal composition, veterinary drug and its preparation
Methods and applications.
Background technique
Calf diarrhea is also known as calf and has loose bowels, and is a kind of gastrointestinal disease that calf often sends out, can occur throughout the year.Calf is normal
Start to fall ill within 2~3 days after birth, to the development of calf, grows, survives etc. and have a significant impact.Especially when jumpbogroup is raised,
For calf diarrhea incidence often as high as 90%~100%, the death rate reaches as high as 50% or more, supports already as China in recent years
The biggest threat of ox industry sustainable and stable development.
Calf diarrhea is as one of cattle-raising common disease and frequently-occurring disease, and clinical manifestation is mainly with paste, liquid or water
Sample, color have stench and foul smell based on yellow, lark, canescence excrement more, are mixed with the incomplete ziega of digestion, hair
Sick calf body temperature is normal or slightly increases, tired mind, and part defecation is in spurting, and dehydration occurs in course of disease elder and acid poisoning is existing
As.As intensive culture and mobility increase, calf diarrhea is at ascendant trend, and modern veterinary clinic is research shows that large intestine bar
The bacterium infections such as bacterium, salmonella may occur in which this disease.This disease course of disease is longer, easy recurrent exerbation, it is more refractory more, the calf death rate
It is high.Under existing rearing conditions, generally infected cattle is treated using antibiotic, but since antibiosis is abused for a long time by raising producer
The reason of element, causes bacterial drug resistance to increase, therapeutic effect is easy to repeatedly.
Therefore, unsatisfactory in view of existing treatment method, at this moment just need the Chinese medicine veterinary pharmacy traditional with China
Theory, using natural medicinal plants, research and develop it is a kind of with clearing heat and detoxicating, invigorating the spleen to dry, inducing astrigency antidiarrheal efficacy it is for animals
Chinese medicine composition, and then good the problem of alleviating calf bacterial diarrhea, become very necessary and urgent.
In view of this, the present invention is specifically proposed.
Summary of the invention
The first object of the present invention is to provide a kind of veterinary Chinese medicinal composition, and the veterinary Chinese medicinal composition has heat-clearing
The effect of removing toxic substances, invigorating the spleen to dry, inducing astrigency antidiarrheal, and then existing livestock-raising field calf bacterial diarrhea is alleviated well
Problem.
The second object of the present invention is to provide a kind of veterinary drug, the veterinary drug through inventor the traditional theory of Chinese veterinarian base
Research obtains on plinth, has effects that clearing heat and detoxicating, invigorating the spleen to dry, inducing astrigency antidiarrheal, has for damp and hot caused calf diarrhea
The effect prevented and treated well, at the same veterinary drug of the present invention be pure plant preparation, without any side effects and drug resistance,
It is suitable for the extensive prophylactic use in major vaccary.
The third object of the present invention is to provide a kind of preparation method of veterinary Chinese medicinal composition, the veterinary Chinese medicine group
The preparation method for closing object is simple, and complicated process equipment is not needed in preparation process, is easy to grasp, can be according to the quantity of calf
A large amount of or a small amount of preparations is carried out, application is facilitated.
The fourth object of the present invention is to provide the application of a kind of veterinary Chinese medicinal composition or veterinary drug, the veterinary Chinese medicine
Composition or veterinary drug can be widely applied to preparation and prevent and treat in calf bacterial diarrhea drug.
A kind of veterinary Chinese medicinal composition provided by the invention, in parts by weight, the Chinese medicine composition mainly by with
Lower component is made:
7~15 parts of the Chinese bulbul, 3~6 parts of the coptis, 3~6 parts of Cortex Phellodendri, 7~15 parts of the bark of ash, 3~6 parts of granatum, Poria cocos 7~
15 parts, 12~18 parts of Rhizoma Atractylodis Macrocephalae and 3~6 parts of Radix Glycyrrhizae.
Further, in parts by weight, the Chinese medicine composition is mainly made of the following components:
8~12 parts of the Chinese bulbul, 4~5 parts of the coptis, 4~5 parts of Cortex Phellodendri, 8~12 parts of the bark of ash, 4~5 parts of granatum, Poria cocos 8~
12 parts, 14~16 parts of Rhizoma Atractylodis Macrocephalae and 4~5 parts of Radix Glycyrrhizae.
Further, in parts by weight, the Chinese medicine composition is mainly made of the following components:
10 parts of the Chinese bulbul, 5 parts of the coptis, 5 parts of Cortex Phellodendri, 10 parts of the bark of ash, 5 parts of granatum, 10 parts of Poria cocos, 15 parts of Rhizoma Atractylodis Macrocephalae and Radix Glycyrrhizae
5 parts.
The veterinary drug that a kind of veterinary Chinese medicinal composition provided by the invention is prepared.
Further, the dosage form of the veterinary drug is oral administration solution.
A kind of preparation method of veterinary drug provided by the invention, the preparation method comprises the following steps:
Filtering and concentrating is made after the veterinary Chinese medicinal composition is decocted with water.
Further, the mass ratio of veterinary Chinese medicinal composition and water is 1:260~300 in the decoction process.
Further, the preparation method further includes the steps that impregnating veterinary Chinese medicinal composition before decoction.
A kind of above-mentioned veterinary Chinese medicinal composition provided by the invention or above-mentioned veterinary drug are in preparation prevention and treatment calf bacterium
Application in property anti-diarrhea drug.
Further, the veterinary drug gavages in diarrhea calf mouthful according to the dosage of daily 1ml/kg weight, continuous application 3
~5 days.
Compared with prior art, the invention has the benefit that
Veterinary Chinese medicinal composition provided by the invention, the Chinese medicine composition mainly by the Chinese bulbul, the coptis, Cortex Phellodendri, the bark of ash,
Granatum, Poria cocos, Rhizoma Atractylodis Macrocephalae and Radix Glycyrrhizae are made.Wherein, using the Chinese bulbul as monarch drug in a prescription, its pharmacological property of the Chinese bulbul is bitter, and taste is cold, has good
It is clearing heat and detoxicating, the effect of removing heat from the blood and relieve diarrhea, for causing the toxic-heat and blood stasis of calf diarrhea that there is good therapeutic effect.With the coptis,
Cortex Phellodendri is ministerial drug, and the coptis, Cortex Phellodendri are also the medicine of bitter cold, at the same there are also good eliminating dampness removing toxic substances the effect of, the present invention it is for animals in
Drug composition is using it as ministerial drug, and takes the function of its bitter-cold herbs easing dampness, and then increases the clearing heat and detoxicating work of the traditional chinese medicine composition of the invention
With；With the bark of ash, granatum, Poria cocos, Rhizoma Atractylodis Macrocephalae and Radix Glycyrrhizae be assistant be allowed to medicine, the bark of ash while pharmacological property bitter cold, also have inducing astrigency it
Function, but the inducing astrigency of the bark of ash will not influence disease and evil, but there are fine puckery intestines to stop for the functional activities of the body fluid that the inducing astrigency of selectivity is wandered away, granatum
It rushes down, stops blooding, the effect of expelling parasite, and then enhance the antidiarrheal effect of veterinary Chinese medicinal composition of the present invention, keep antidiarrheal more rapid；Fu
Siberian cocklebur, Rhizoma Atractylodis Macrocephalae mainly take the function of its invigorating spleen for diuresis, and then make its diuresis and defecate in fact, while enhancing the transporting function of calf taste
Can, restore diarrhea calf as early as possible.The present invention plays the veterinary Chinese medicinal composition that compounding obtains by above-mentioned each bulk pharmaceutical chemicals altogether to be had
The effect of clearing heat and detoxicating, invigorating the spleen to dry, inducing astrigency antidiarrheal, and then the bacillary abdomen of existing feeding field calf is alleviated well
The problem of rushing down.
Veterinary drug provided by the invention is prepared by above-mentioned veterinary Chinese medicinal composition, through inventor Chinese veterinarian tradition
Research obtains on the basis of theory, has effects that clearing heat and detoxicating, invigorating the spleen to dry, inducing astrigency antidiarrheal, for damp and hot caused calf
Diarrhea has the function of preventing and treating well, while veterinary drug of the present invention is pure plant preparation, without any side effects
And drug resistance, it is suitable for the extensive prophylactic use in major vaccary.
The preparation method of veterinary Chinese medicinal composition provided by the invention is simple, and complicated processing is not needed in preparation process and is set
It is standby, it is easy to grasp, a large amount of or a small amount of preparations can be carried out according to the quantity of calf, facilitate application.
Above-mentioned veterinary Chinese medicinal composition or veterinary drug provided by the invention can be widely applied to preparation and prevent and treat calf
In bacterial diarrhea drug.
Specific embodiment
Technical solution of the present invention is clearly and completely described below in conjunction with embodiment, it is clear that described reality
Applying example is a part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, the common skill in this field
Art personnel every other embodiment obtained without making creative work belongs to the model that the present invention protects
It encloses.
According to an aspect of the present invention, a kind of veterinary Chinese medicinal composition, in parts by weight, the Chinese medicine composition
Mainly it is made of the following components:
7~15 parts of the Chinese bulbul, 3~6 parts of the coptis, 3~6 parts of Cortex Phellodendri, 7~15 parts of the bark of ash, 3~6 parts of granatum, Poria cocos 7~
15 parts, 12~18 parts of Rhizoma Atractylodis Macrocephalae and 3~6 parts of Radix Glycyrrhizae.
Using antibiotic, to the method that calf diarrhea is treated, the effect is unsatisfactory in view of existing, and inventor passes through
The clinical manifestation of diarrhea calf is studied, mainly with paste, liquid or water sample, color is in yellow, lark, canescence excrement
It is main, there is stench and foul smell more, is mixed with the symptom for digesting incomplete ziega, inventor is recognized based on the traditional theory of Chinese veterinarian
Mostly be the gas cut and stomach caused outside calf by epidemic disease caused by damp-heat pathogen poison due to feeding condition is poor for calf diarrhea, it is strongly fragrant hold back in
Middle coke, retention and fumigation of damp-heat inside the body, qi and blood retardance, the malicious knot of mutually fighting of qi and blood and epidemic disease caused by damp-heat pathogen turn to purulence blood, and then the development of evil in febrile disease is not normal and diarrhea occurs；All
It is lower urgent because there is heat then to rush down in calf intestines, so damp-heat gluing each other then let out and it is not well caused by.Therefore pass through experimental study, inventor
Using the Chinese bulbul as monarch drug in a prescription, the coptis, Cortex Phellodendri are ministerial drug, take the function thirdly taste medicine bitter-cold herbs easing dampness, and with the bark of ash, granatum, Poria cocos, white
Art and Radix Glycyrrhizae be assistant be allowed to medicine, inducing astrigency antidiarrheal, and then diuresis and it is real defecate, to calf diarrhea carry out treatment achieve it is very good
Curative effect.
Veterinary Chinese medicinal composition provided by the invention, the Chinese medicine composition mainly by the Chinese bulbul, the coptis, Cortex Phellodendri, the bark of ash,
Granatum, Poria cocos, Rhizoma Atractylodis Macrocephalae and Radix Glycyrrhizae are made.Wherein, using the Chinese bulbul as monarch drug in a prescription, its pharmacological property of the Chinese bulbul is bitter, and taste is cold, has good
It is clearing heat and detoxicating, the effect of removing heat from the blood and relieve diarrhea, for causing the toxic-heat and blood stasis of calf diarrhea that there is good therapeutic effect.With the coptis,
Cortex Phellodendri is ministerial drug, and the coptis, Cortex Phellodendri are also the medicine of bitter cold, at the same there are also good eliminating dampness removing toxic substances the effect of, the present invention it is for animals in
Drug composition is using it as ministerial drug, and takes the function of its bitter-cold herbs easing dampness, and then increases the clearing heat and detoxicating work of the traditional chinese medicine composition of the invention
With；With the bark of ash, granatum, Poria cocos, Rhizoma Atractylodis Macrocephalae and Radix Glycyrrhizae be assistant be allowed to medicine, the bark of ash while pharmacological property bitter cold, also have inducing astrigency it
Function, but the inducing astrigency of the bark of ash will not influence disease and evil, but there are fine puckery intestines to stop for the functional activities of the body fluid that the inducing astrigency of selectivity is wandered away, granatum
It rushes down, stops blooding, the effect of expelling parasite, and then enhance the antidiarrheal effect of veterinary Chinese medicinal composition of the present invention, keep antidiarrheal more rapid；Fu
Siberian cocklebur, Rhizoma Atractylodis Macrocephalae mainly take the function of its invigorating spleen for diuresis, and then make its diuresis and defecate in fact, while enhancing the transporting function of calf taste
Can, restore diarrhea calf as early as possible.The present invention plays the veterinary Chinese medicinal composition that compounding obtains by above-mentioned each bulk pharmaceutical chemicals altogether to be had
The effect of clearing heat and detoxicating, invigorating the spleen to dry, inducing astrigency antidiarrheal, and then the bacillary abdomen of existing feeding field calf is alleviated well
The problem of rushing down.
The above-mentioned Chinese bulbul is typical but typical but non-limiting preferred embodiment are as follows: 7 parts, 8 parts, 9 parts, 10 parts, 11 parts,
12 parts, 13 parts, 14 parts and 15 parts；Above-mentioned coptis typical case but typical but non-limiting preferred embodiment are as follows: 3 parts, 4 parts, 5 parts
With 6 parts；Above-mentioned Cortex Phellodendri typical case but typical but non-limiting preferred embodiment are as follows: 3 parts, 4 parts, 5 parts and 6 parts；The above-mentioned bark of ash
Typical but typical but non-limiting preferred embodiment are as follows: 7 parts, 8 parts, 9 parts, 10 parts, 11 parts, 12 parts, 13 parts, 14 parts and 15
Part；Above-mentioned granatum typical case but typical but non-limiting preferred embodiment are as follows: 3 parts, 4 parts, 5 parts and 6 parts；Above-mentioned Poria cocos allusion quotation
Type but typical but non-limiting preferred embodiment are as follows: 7 parts, 8 parts, 9 parts, 10 parts, 11 parts, 12 parts, 13 parts, 14 parts and 15
Part；Above-mentioned Rhizoma Atractylodis Macrocephalae typical case but typical but non-limiting preferred embodiment are as follows: 12 parts, 13 parts, 14 parts, 15 parts, 16 parts, 17 parts
With 18 parts；Above-mentioned Radix Glycyrrhizae typical case but typical but non-limiting preferred embodiment are as follows: 3 parts, 4 parts, 5 parts and 6 parts.
In the preferred embodiment of the present invention, in parts by weight, the Chinese medicine composition is mainly by following
Component is made:
8~12 parts of the Chinese bulbul, 4~5 parts of the coptis, 4~5 parts of Cortex Phellodendri, 8~12 parts of the bark of ash, 4~5 parts of granatum, Poria cocos 8~
12 parts, 14~16 parts of Rhizoma Atractylodis Macrocephalae and 4~5 parts of Radix Glycyrrhizae.
In above-mentioned preferred embodiment, in parts by weight, the Chinese medicine composition is mainly made of the following components:
10 parts of the Chinese bulbul, 5 parts of the coptis, 5 parts of Cortex Phellodendri, 10 parts of the bark of ash, 5 parts of granatum, 10 parts of Poria cocos, 15 parts of Rhizoma Atractylodis Macrocephalae and Radix Glycyrrhizae
5 parts.
In the present invention, by the further adjustment and optimization to each component raw material dosage ratio, to advanced optimize
The drug effect of veterinary Chinese medicinal composition of the present invention.
According to an aspect of the present invention, a kind of veterinary drug that veterinary Chinese medicinal composition is prepared.
Veterinary drug provided by the invention is prepared by above-mentioned veterinary Chinese medicinal composition, through inventor Chinese veterinarian tradition
Research obtains on the basis of theory, has effects that clearing heat and detoxicating, invigorating the spleen to dry, inducing astrigency antidiarrheal, for damp and hot caused calf
Diarrhea has the function of preventing and treating well, while veterinary drug of the present invention is pure plant preparation, without any side effects
And drug resistance, it is suitable for the extensive prophylactic use in major vaccary.
In the preferred embodiment of the present invention, the dosage form of the veterinary drug is oral administration solution.
As a preferred embodiment, the dosage form of above-mentioned veterinary drug is oral administration solution, oral administration solution is more conducive to and feed
Mix is carried out, thus the feeding of more conducively calf, the palatability of drug is preferable.
Preferably, it can be to draw with white sugar during feeding, be added in feed, and then neutralize the bitter taste of veterinary drug.
According to an aspect of the present invention, a kind of preparation method of veterinary drug, the preparation method comprises the following steps: by institute
Filtering and concentrating after veterinary Chinese medicinal composition is decocted with water is stated to be made.
The preparation method of veterinary Chinese medicinal composition provided by the invention is simple, and complicated processing is not needed in preparation process and is set
It is standby, it is easy to grasp, a large amount of or a small amount of preparations can be carried out according to the quantity of calf, facilitate application.
In the preferred embodiment of the present invention, in the decoction process veterinary Chinese medicinal composition and water mass ratio
For 1:260~300.
Implementation method as one preferred, the mass ratio of veterinary Chinese medicinal composition and water is 1 in above-mentioned decoction process:
260；1:270；1:280；1:290；1:300.
Preferably, the decoction can be for twice, each time be 1~2 hour.
In the preferred embodiment of the present invention, the preparation method further includes combining before decoction to veterinary Chinese medicine
The step of object is impregnated.
As a preferred embodiment, above-mentioned preparation method further includes carrying out before decoction to veterinary Chinese medicinal composition
The step of immersion, the time of the immersion are 0.5~1 hour.
Preferably, the veterinary drug preparation method specifically includes the following steps:
(a), veterinary Chinese medicinal composition is weighed by above-mentioned mass fraction and be soaked in pure water 0.5~1 hour, the beast
Mass ratio with Chinese medicine composition and pure water is 1:260~300；
(b), veterinary Chinese medicinal composition is decocted with soak after impregnating, is first boiled by intense fire, rear mild fire boiling decocts 1~2
Hour, then with the strainer filtering of 100 meshes, it is spare to obtain filtrate A；
(c), pure water is added in filtered veterinary Chinese medicinal composition according to the method for step (b) again and carries out secondary decoct
It boils, obtains liquor B, mild fire boiling boiling down is reduced to the 20% of original volume after filtrate A and liquor B are merged, and obtains the veterinary drug.
According to an aspect of the present invention, a kind of above-mentioned veterinary Chinese medicinal composition or above-mentioned veterinary drug are prevented and treated in preparation
Application in calf bacterial diarrhea drug.
Above-mentioned veterinary Chinese medicinal composition or veterinary drug provided by the invention can be widely applied to preparation and prevent and treat calf
In bacterial diarrhea drug.
In the preferred embodiment of the present invention, the veterinary drug is gavaged according to the dosage of daily 1ml/kg weight in abdomen
It rushes down in calf mouthful, continuous application 3~5 days.
Technical solution of the present invention is described further below in conjunction with embodiment and comparative example.
Embodiment 1
A kind of veterinary Chinese medicinal composition, according to weight grams meter, the Chinese medicine composition is mainly made of the following components:
Chinese bulbul 7g, coptis 3g, Cortex Phellodendri 3g, bark of ash 7g, granatum 6g, Poria cocos 15g, Rhizoma Atractylodis Macrocephalae 18g and Radix Glycyrrhizae 6g；
A kind of veterinary drug, the veterinary drug are prepared by above-mentioned veterinary Chinese medicinal composition, and the preparation method of the veterinary drug is specific
The following steps are included:
(a), above-mentioned veterinary Chinese medicinal composition is soaked in pure water 0.5~1 hour first, the quality of the pure water
For 1500ml；
(b), veterinary Chinese medicinal composition is decocted with soak after impregnating, is first boiled by intense fire, rear mild fire boiling decocts 1~2
Hour, then with the strainer filtering of 100 meshes, it is spare to obtain filtrate A；
(c), pure water is added in filtered veterinary Chinese medicinal composition according to the method for step (b) again and carries out secondary decoct
It boils, obtains liquor B, mild fire boiling boiling down is reduced to 500ml after filtrate A and liquor B are merged, and obtains the veterinary drug.
Embodiment 2
A kind of veterinary Chinese medicinal composition, according to weight grams meter, the Chinese medicine composition is mainly made of the following components:
Chinese bulbul 15g, coptis 6g, Cortex Phellodendri 6g, bark of ash 15g, granatum 3g, Poria cocos 7g, Rhizoma Atractylodis Macrocephalae 12g and Radix Glycyrrhizae 3g；
A kind of veterinary drug, the veterinary drug are prepared by above-mentioned veterinary Chinese medicinal composition, and the preparation method of the veterinary drug is the same as real
Apply example 1.
Embodiment 3
A kind of veterinary Chinese medicinal composition, according to weight grams meter, the Chinese medicine composition is mainly made of the following components:
8 parts of the Chinese bulbul, 4 parts of the coptis, 4 parts of Cortex Phellodendri, 12 parts of the bark of ash, 5 parts of granatum, 12 parts of Poria cocos, 16 parts of Rhizoma Atractylodis Macrocephalae and Radix Glycyrrhizae 5
Part；
A kind of veterinary drug, the veterinary drug are prepared by above-mentioned veterinary Chinese medicinal composition, and the preparation method of the veterinary drug is the same as real
Apply example 1.
Embodiment 4
A kind of veterinary Chinese medicinal composition, according to weight grams meter, the Chinese medicine composition is mainly made of the following components:
12 parts of the Chinese bulbul, 5 parts of the coptis, 5 parts of Cortex Phellodendri, 8 parts of the bark of ash, 4 parts of granatum, 8 parts of Poria cocos, 14 parts of Rhizoma Atractylodis Macrocephalae and Radix Glycyrrhizae 4
Part；
A kind of veterinary drug, the veterinary drug are prepared by above-mentioned veterinary Chinese medicinal composition, and the preparation method of the veterinary drug is the same as real
Apply example 1.
Embodiment 5
A kind of veterinary Chinese medicinal composition, according to weight grams meter, the Chinese medicine composition is mainly made of the following components:
10 parts of the Chinese bulbul, 5 parts of the coptis, 5 parts of Cortex Phellodendri, 10 parts of the bark of ash, 5 parts of granatum, 10 parts of Poria cocos, 15 parts of Rhizoma Atractylodis Macrocephalae and Radix Glycyrrhizae
5 parts；
A kind of veterinary drug, the veterinary drug are prepared by above-mentioned veterinary Chinese medicinal composition, and the preparation method of the veterinary drug is the same as real
Apply example 1.
Comparative example 1
A kind of veterinary Chinese medicinal composition, according to weight grams meter, the Chinese medicine composition is mainly made of the following components:
Chinese bulbul 18g, coptis 10g, Cortex Phellodendri 2g, bark of ash 17g, granatum 2g, Poria cocos 17g, Rhizoma Atractylodis Macrocephalae 10g and Radix Glycyrrhizae 7g；
A kind of veterinary drug, the veterinary drug are prepared by above-mentioned veterinary Chinese medicinal composition, and the preparation method of the veterinary drug is the same as real
Apply example 1.
As different from Example 5, the content of each component is not mentioned this comparative example in the present invention in veterinary Chinese medicinal composition
For in the range of.
Comparative example 2
This comparative example is not in addition to including granatum in veterinary Chinese medicinal composition, remaining is the same as embodiment 5.
Comparative example 3
This comparative example is not in addition to including Poria cocos, Rhizoma Atractylodis Macrocephalae in veterinary Chinese medicinal composition, remaining is the same as embodiment 5.
Experimental example 1
To show that veterinary Chinese medicinal composition of the present invention has effects that clearing heat and detoxicating, invigorating the spleen to dry, inducing astrigency antidiarrheal, and then very
It is good the problem of alleviating existing feeding field calf bacterial diarrhea.Inventor Henan Zhumadian, Nanyang, Xuchang and
The four large-scale vaccary in Zhengzhou carries out using test veterinary drug made from veterinary Chinese medicinal composition of the present invention.
Concrete application method are as follows: between 1~June in 2018 in above-mentioned vaccary, calf diarrhea occurs after birth in 1 monthly age
The calf of illness, mainly with paste, liquid or water sample, color is in yellow, lark, canescence excrement for the calf diarrhea clinical manifestation
Just based on, there is stench and foul smell more, be mixed with the incomplete ziega of digestion, morbidity calf body temperature is normal or slightly increases, essence
Refreshing burnout, part defecation is in spurting, is counted totally 177.
9 experimental groups are divided into, experimental group 1~8 every group 20, experimental group 9 includes other 17 as control.It is wherein real
It tests group 1~8 to treat diarrhea calf using the veterinary drug that Examples 1 to 5 and comparative example 1~3 are prepared, according to daily
The dosage of 1ml/kg weight gavage in diarrhea calf mouthful, continuous application 5 days.Experimental group 9 using traditional antibiotic method into
Row treatment.
The judgment criteria of therapeutic effect is as follows:
Cure: calf diarrhea symptom completely disappears, and mental status restores good, and calf feeding restores normal, weight recovery
Arm's length standard；
Effective: calf diarrhea symptom disappears substantially, and calf feeding restores normal, and weight is slightly light compared with arm's length standard, body shape
During condition is gradually recovered, after the later period raises 60 days, normal level is fully achieved；
Effective: calf diarrhea symptom has larger improvement, and calf feeding restores normal, and weight is slightly light compared with arm's length standard, rear
It is final to eliminate after phase raises 60 days；
Invalid: dead or calf diarrhea symptom does not improve；
Cure rate=(curing number+effective number)/experiment sum * 100%；
Total effective rate=(curing number+effective number+significant figure)/experiment sum * 100%.
Table 1: the result of each processing group treatment calf diarrhea
As seen from the above table, the above-mentioned veterinary drug being prepared using Examples 1 to 5 treats diarrhea calf, total effective
Rate is 100%, and cure rate illustrates that veterinary Chinese medicinal composition of the present invention has clearing heat and detoxicating, invigorating the spleen to dry, inducing astrigency 90% or more
The effect of antidiarrheal, and then the problem of alleviate existing feeding field calf bacterial diarrhea well, and use tradition anti-
The calf cure rate of raw extract for treating is only 75%, and effective percentage is only 80%.
Meanwhile in 1 veterinary Chinese medicinal composition of comparative example each component content not in range provided by the present invention, and
Comparative example 2 does not include granatum, comparative example 3 does not include Poria cocos, veterinary drug made from Rhizoma Atractylodis Macrocephalae, is unable to reach corresponding treatment effect yet
Fruit.
In addition, inventor adopts to show that veterinary drug produced by the present invention can play good prevention effect to calf diarrhea
The veterinary drug being prepared with embodiment 5, between above-mentioned 4 vaccaries calf being born 7~September in 2018 the 2nd day after birth
Carried out that preventative perfusion is primary every 1 day, every calf is gavaged by the veterinary drug amount of daily 1ml/kg weight, continuously gavages 5
Secondary, carrying out the calf of preventative medication through later observation, there is no the symptoms of calf diarrhea, then the raising of 60 days postmenstruations to see
It examines, normal level is fully achieved in the preventative calf taken, generates in the entire experiment process without any side effect.
Finally, it should be noted that the above embodiments are only used to illustrate the technical solution of the present invention., rather than its limitations；To the greatest extent
Pipe present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that: its according to
So be possible to modify the technical solutions described in the foregoing embodiments, or to some or all of the technical features into
Row equivalent replacement；And these are modified or replaceed, various embodiments of the present invention technology that it does not separate the essence of the corresponding technical solution
The range of scheme.
Claims (10)
1. a kind of veterinary Chinese medicinal composition, which is characterized in that in parts by weight, the Chinese medicine composition is mainly by with the following group
Divide and be made: 7~15 parts of the Chinese bulbul, 3~6 parts of the coptis, 3~6 parts of Cortex Phellodendri, 7~15 parts of the bark of ash, 3~6 parts of granatum, Poria cocos 7~15
Part, 12~18 parts of Rhizoma Atractylodis Macrocephalae and 3~6 parts of Radix Glycyrrhizae.
2. veterinary Chinese medicinal composition according to claim 1, which is characterized in that in parts by weight, the Chinese medicine group
It closes object to be mainly made of the following components: 8~12 parts of the Chinese bulbul, 4~5 parts of the coptis, 4~5 parts of Cortex Phellodendri, 8~12 parts of the bark of ash, granatum
4~5 parts, 8~12 parts of Poria cocos, 14~16 parts of Rhizoma Atractylodis Macrocephalae and 4~5 parts of Radix Glycyrrhizae.
3. veterinary Chinese medicinal composition according to claim 1, which is characterized in that in parts by weight, the Chinese medicine group
It closes object to be mainly made of the following components: 10 parts of the Chinese bulbul, 5 parts of the coptis, 5 parts of Cortex Phellodendri, 10 parts of the bark of ash, 5 parts of granatum, Poria cocos 10
Part, 15 parts of Rhizoma Atractylodis Macrocephalae and 5 parts of Radix Glycyrrhizae.
4. the veterinary drug that a kind of any one according to claim 1~3 veterinary Chinese medicinal composition is prepared.
5. veterinary drug according to claim 4, which is characterized in that the dosage form of the veterinary drug is oral administration solution.
6. a kind of preparation method of veterinary drug according to claim 4, which is characterized in that the preparation method includes following step
It is rapid:
Filtering and concentrating is made after the veterinary Chinese medicinal composition is decocted with water.
7. the preparation method of veterinary drug according to claim 6, which is characterized in that veterinary Chinese medicinal composition in the decoction process
Mass ratio with water is 1:260~300.
8. the preparation method of veterinary drug according to claim 6, which is characterized in that the preparation method further includes right before decoction
The step of veterinary Chinese medicinal composition is impregnated.
9. veterinary drug described in a kind of veterinary Chinese medicinal compositions described in any item according to claim 1~3 or claim 4,5 exists
Preparation prevents and treats the application in calf bacterial diarrhea drug.
10. the application of veterinary drug according to claim 9, which is characterized in that the veterinary drug is according to daily 1ml/kg weight
Dosage gavages in diarrhea calf mouthful, and continuous application 3~5 days.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110279771A (en) * | 2019-06-21 | 2019-09-27 | 广西壮族自治区药用植物园 | A kind of Chinese medicine pre-mixing agent and preparation method thereof for preventing and treating bamboo rat diarrhea |
| CN112843138A (en) * | 2021-03-13 | 2021-05-28 | 中国农业科学院兰州畜牧与兽药研究所 | Traditional Chinese medicine composition for preventing and treating calf damp-heat diarrhea and preparation method and application thereof |
| CN114796336A (en) * | 2022-03-24 | 2022-07-29 | 山东畜牧兽医职业学院 | Traditional Chinese medicine composition for preventing and assisting in treating infectious bovine gastroenteritis |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102579682A (en) * | 2012-03-09 | 2012-07-18 | 李承平 | Medicine combination for clearing away heat and toxic material |
| CN103007216A (en) * | 2012-11-25 | 2013-04-03 | 荣成市崖头美全口腔诊所 | Chinese medicinal composition for treating chronic diarrhea |
| CN103893299A (en) * | 2012-12-28 | 2014-07-02 | 党彬 | Pure traditional Chinese medicine preparation for treating infantile diarrhea |
| CN103893344A (en) * | 2014-02-14 | 2014-07-02 | 四川英格瑞生物科技有限公司 | Chinese medicinal submicron powder for treating piglet's yellow-white dysentery and preparation method thereof |
| CN104606664A (en) * | 2015-02-13 | 2015-05-13 | 安徽恒源药业有限公司 | Anti-diarrheal traditional Chinese medicine powder for poultry |
| CN107970374A (en) * | 2017-12-21 | 2018-05-01 | 霍山县中医院 | Treat the Chinese medicinal formulae of chronic diarrhea |
| CN108524594A (en) * | 2018-04-03 | 2018-09-14 | 何洁 | Invigorating the spleen herbal medicine tea composition, invigorating the spleen herbal medicine tea formulation and preparation method thereof |
| CN108686021A (en) * | 2018-08-15 | 2018-10-23 | 福建傲农生物科技集团股份有限公司 | A kind of plant fermentation object and preparation method thereof of prevention diarrhea of pigs |
| CN108904769A (en) * | 2018-08-09 | 2018-11-30 | 紫云自治县翔锋种养殖农民专业合作社 | A kind of pharmaceutical composition and preparation method thereof for treating Black Hills sheep dysentery |
-
2018
- 2018-12-18 CN CN201811551909.0A patent/CN109331079A/en active Pending
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102579682A (en) * | 2012-03-09 | 2012-07-18 | 李承平 | Medicine combination for clearing away heat and toxic material |
| CN103007216A (en) * | 2012-11-25 | 2013-04-03 | 荣成市崖头美全口腔诊所 | Chinese medicinal composition for treating chronic diarrhea |
| CN103893299A (en) * | 2012-12-28 | 2014-07-02 | 党彬 | Pure traditional Chinese medicine preparation for treating infantile diarrhea |
| CN103893344A (en) * | 2014-02-14 | 2014-07-02 | 四川英格瑞生物科技有限公司 | Chinese medicinal submicron powder for treating piglet's yellow-white dysentery and preparation method thereof |
| CN104606664A (en) * | 2015-02-13 | 2015-05-13 | 安徽恒源药业有限公司 | Anti-diarrheal traditional Chinese medicine powder for poultry |
| CN107970374A (en) * | 2017-12-21 | 2018-05-01 | 霍山县中医院 | Treat the Chinese medicinal formulae of chronic diarrhea |
| CN108524594A (en) * | 2018-04-03 | 2018-09-14 | 何洁 | Invigorating the spleen herbal medicine tea composition, invigorating the spleen herbal medicine tea formulation and preparation method thereof |
| CN108904769A (en) * | 2018-08-09 | 2018-11-30 | 紫云自治县翔锋种养殖农民专业合作社 | A kind of pharmaceutical composition and preparation method thereof for treating Black Hills sheep dysentery |
| CN108686021A (en) * | 2018-08-15 | 2018-10-23 | 福建傲农生物科技集团股份有限公司 | A kind of plant fermentation object and preparation method thereof of prevention diarrhea of pigs |
Non-Patent Citations (2)
| Title |
|---|
| 徐倩倩等: "白头翁汤方及其单味药水提取液对猪、鸡大肠杆菌体外抑菌活性的测定", 《黑龙江畜牧兽医》 * |
| 杨森等: "中草药对仔猪下痢的防治效果", 《陕西农业科学》 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110279771A (en) * | 2019-06-21 | 2019-09-27 | 广西壮族自治区药用植物园 | A kind of Chinese medicine pre-mixing agent and preparation method thereof for preventing and treating bamboo rat diarrhea |
| CN112843138A (en) * | 2021-03-13 | 2021-05-28 | 中国农业科学院兰州畜牧与兽药研究所 | Traditional Chinese medicine composition for preventing and treating calf damp-heat diarrhea and preparation method and application thereof |
| CN114796336A (en) * | 2022-03-24 | 2022-07-29 | 山东畜牧兽医职业学院 | Traditional Chinese medicine composition for preventing and assisting in treating infectious bovine gastroenteritis |
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