CN102327329A - Rhubarb-containing composition and application thereof - Google Patents

Rhubarb-containing composition and application thereof Download PDF

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Publication number
CN102327329A
CN102327329A CN201110291990A CN201110291990A CN102327329A CN 102327329 A CN102327329 A CN 102327329A CN 201110291990 A CN201110291990 A CN 201110291990A CN 201110291990 A CN201110291990 A CN 201110291990A CN 102327329 A CN102327329 A CN 102327329A
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China
Prior art keywords
parts
radix
composition
rhizoma rhei
compositions
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CN201110291990A
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Chinese (zh)
Inventor
刘易通
王庆福
李振天
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GUANGDONG ZIJIN ZHENGTIAN PHARMACEUTICAL CO Ltd
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GUANGDONG ZIJIN ZHENGTIAN PHARMACEUTICAL CO Ltd
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Priority to CN201110291990A priority Critical patent/CN102327329A/en
Publication of CN102327329A publication Critical patent/CN102327329A/en
Pending legal-status Critical Current

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Abstract

The invention relates to a rhubarb-containing composition and application thereof. The composition comprises the following raw materials or extracts of the raw materials or chemically-acceptable derivatives of the raw material extracts; the raw materials include processed products thereof; and the composition comprises 100 parts by weight of rhubarb, on the basis, and further comprises but is not limited to one or more of antifeverile dichroa root, Chinese thorowax root, sweet wormwood, rangooncreeper fruit, Chinese pulsatilla root, ash bark, lalang grass rhizome, hairyvein agrimonia herb and bud, beautyberry, moutan bark, elecampane inula root and liquoric root which can be added according to specific situations. The composition can be prepared into medicinally or pharmaceutically-acceptable physical forms such as powder, liquids, paste, particles, capsules and the like. The composition can be used for preventing and treating coccidiosis, relieving pathological injuries caused by coccidian, relieving the illnesses, and lowering economic loss.

Description

A kind of composition and use thereof that contains Radix Et Rhizoma Rhei
Technical field
The present invention relates to a kind of composition and use thereof that contains Radix Et Rhizoma Rhei and belong to the animal and veterinary technical field, be mainly used in prevention and treat coccidiosis, alleviate pathologic damage that coccidiosis causes and mitigate the disease, reduction economic loss.
Background technology
In worldwide animal husbandry field; Annual nearly 10,000,000,000 dollars of the economic loss that pathologic damage causes dead or production capacity to descend causing takes place because of infecting coccidiosis; Though the annual medicine that is used for anticoccidial surpasses multi-million dollar; Such as various kinds such as Amprolium, sulfonamides, diclazuril, Toltrazuril, horse degree mycins; But still can not avoid because of infecting the loss that coccidiosis brings, and these medicines have mostly, and safety range is little, the risk of high residue, directly influences food safety, threaten human health.So countries in the world have turned to the development and research of pure natural plant medicine and Chinese medicine one after another.
Chinese medicine and compatibility thereof advocate finally to make the whole coordinated development that realizes through conditioning, each item function of regulating body, no drug residue, can not develop immunity to drugs; Natural plants and extract component safety thereof, efficient, stable, controlled, utilizing natural plants and Chinese medicine instead of chemical medicine has been world trends.Therefore, the effectively anti-system of research and utilization natural plant and Chinese medicine coccidiosis, alleviate pathologic damage that coccidiosis causes, reduce because of infecting the economic loss that coccidiosis brings and be endowed more expectation.
Be familiar with coccidiosis with Traditional Chinese medical theory,, control when purging FU-organs detoxifcation, removing mass clots absorbing when being the epidemic disease poison card in strongly fragrant.Radix Et Rhizoma Rhei bitter in the mouth cold in nature is gone into spleen, stomach, large intestine channel, belongs to cathartic drug, purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, removing mass clots absorbing is arranged, push away the old new merit that causes, and often controls excess-heat, furunculosis and so on.In addition; The article that also can add the hemostasis of parasite killing such as Radix Dichroae, Radix Bupleuri, Herba Artemisiae Annuae, Fructus Quisqualis, the Radix Pulsatillae, Cortex Fraxini, Rhizoma Imperatae, Herba Agrimoniae, Folium Callicarpae Formosanae, Cortex Moutan, Radix Inulae, Radix Glycyrrhizae, circulation of qi promoting removing food stagnancy are with purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, the removing mass clots absorbing of strengthening realizing Radix Et Rhizoma Rhei, push away the old new merit that causes.Therefore,, be used to prevent and treat coccidiosis, alleviate the pathologic damage that coccidiosis causes and have active operation significance as main component with the derivant that chemically can accept form that contains Radix Et Rhizoma Rhei or its extract, extract.
Summary of the invention
The present invention aims to provide a kind of composition and use thereof that contains Radix Et Rhizoma Rhei, and said composition is through prevention and treat coccidiosis, alleviate pathologic damage that coccidiosis causes and mitigate the disease, reduction economic loss.
A kind of composition and use thereof that contains Radix Et Rhizoma Rhei of the present invention contains the raw material of following parts by weight, perhaps this raw material=extract, the perhaps derivant of the form of chemically can accepting of this raw extract, said raw material comprises its processed product; The composition and the parts by weight of described compositions are: 100 parts of Radix Et Rhizoma Rhei.
Can increase as the case may be on this basis but be not limited to following parts by weight one or more components: 50~150 parts of Radix Dichroaes, 50~150 parts of Radix Bupleuri, 50~150 parts of Herba Artemisiae Annuaes; 60~120 parts of Fructus Quisqualis, 60~120 parts of the Radix Pulsatillaes, 60~100 parts of Cortex Fraxinis; 50~150 parts of Rhizoma Imperataes, 50~150 parts of Herba Agrimoniaes, Folium Callicarpae Formosanae 70~110; 50~150 parts of Cortex Moutans, 50~150 parts of Radix Inulaes, 50~150 parts in Radix Glycyrrhizae.
The present composition can be prepared into medicine or pharmaceutically acceptable physical aspects such as powder, liquid, paste, granule or capsule, and said composition is used for through prevention and treats coccidiosis, alleviates pathologic damage that coccidiosis causes and mitigate the disease, reduction economic loss.
Compositions method for using according to the invention and use amount are: press 0.1~10.0% of complete feed weight behind the compositions pulverizing mix homogeneously and mix use; Or said composition processed form such as liquid with water extraction, the content of medicinal liquid Chinese crude drug is: the 1ml medicinal liquid is equivalent to the 1g raw medicinal herbs at least, converts water 10kg~3000kg by 1 Hydrargyri Oxydum Rubrum liquid and freely drinks for the chicken crowd.
Compositions of the present invention has the merit of purging heat and dredging bowels, removing heat from blood removing blood stasis, detoxifcation parasite killing, can be through prevention and treat coccidiosis, alleviate pathologic damage that coccidiosis causes and mitigate the disease, reduction economic loss.
Compositions of the present invention is through check, and its poisonous and harmful substance plumbous (pb), arsenic (As) content all do not surpass " two ones of Chinese veterinary drug allusion quotations " specified standard.
The specific embodiment
Through embodiment the present invention is explained further details below, these embodiment only are used for explaining the present invention, do not limit the scope of the invention.
Embodiment 1: 100 parts of Radix Et Rhizoma Rhei.Above composition is pulverized or extracts behind the medicinal liquid subsequent use, and the content of medicinal liquid Chinese crude drug is: the 1ml medicinal liquid is equivalent to the 1g raw medicinal herbs at least.
Embodiment 2: 10 parts of Radix Et Rhizoma Rhei, 20 parts of Radix Bupleuri, 30 parts of Radix Dichroaes.It is subsequent use or extract behind the medicinal liquid subsequent usely that above composition is pulverized the back mix homogeneously, and the content of medicinal liquid Chinese crude drug is: the 1ml medicinal liquid is equivalent to the 1g raw medicinal herbs at least.
Embodiment 3: 20 parts of Radix Et Rhizoma Rhei, 20 parts of Radix Bupleuri, 30 parts of Radix Dichroaes, 20 parts of Cortex Moutans, 10 parts in Radix Glycyrrhizae.It is subsequent use or extract behind the medicinal liquid subsequent usely that above composition is pulverized the back mix homogeneously, and the content of medicinal liquid Chinese crude drug is: the 1ml medicinal liquid is equivalent to the 1g raw medicinal herbs at least.
Embodiment 4: 20 parts of Radix Et Rhizoma Rhei, 30 parts of Radix Dichroaes, 20 parts of Radix Bupleuri, 20 parts of Cortex Moutans, 20 parts of Herba Artemisiae Annuaes, 10 parts of Rhizoma Imperataes.It is subsequent use or extract behind the medicinal liquid subsequent usely that above composition is pulverized the back mix homogeneously, and the content of medicinal liquid Chinese crude drug is: the 1ml medicinal liquid is equivalent to the 1g raw medicinal herbs at least.
The part test final report:
The test report that contains the composition and use thereof of Radix Et Rhizoma Rhei
Select for use certain to make a definite diagnosis 3700 of chickling that infect coccidiosis, 60 of random chooses are as blank, and all the other are equally divided into two groups of A, B.Online flat supporting keeps clean, notes ventilating, and carries out record.Feedstuff is prepared basal diet with reference to NRC feeding of broiler standard, and free choice feeding is freely drunk water, unified management.The A group is added this extract (being produced jointly by the positive day pharmaceutcal corporation, Ltd of Guangdong Zijin, herbal medicine engineering and technological research development centre, Guangdong Province), converts water 0.5kg by 1ml and freely drinks; The B group is 0.5% solution of diclazuril group (being provided by veterinary drug engineering and technological research development centre, Heyuan City), converts water 5kg by medicinal liquid 1ml and freely drinks; The C group is the blank group.
Table 1 A, B, three groups of treatments of C comparative test result
Figure 524879DEST_PATH_IMAGE001
Can find out that by table 1 used this kind to contain the sick chicken of the combination treatment of Radix Et Rhizoma Rhei, dead quantity obviously descended since the 3rd day; Feed intake is obviously recovered; The hemafecia color just took a turn for the better after the medication in second day to some extent, four days basic end of medicine for treatment, and effect is superior to matched group.Therefore explain that this kind compositions has the merit of purging heat and dredging bowels, removing heat from blood removing blood stasis, detoxifcation parasite killing, can be through prevention and treat coccidiosis, alleviate pathologic damage that coccidiosis causes and mitigate the disease, reduction economic loss.

Claims (4)

1. a compositions that contains Radix Et Rhizoma Rhei is characterized in that said compositions contains the raw material of following parts by weight, the perhaps extract of this raw material, and the perhaps derivant of the form of chemically can accepting of this raw extract, said raw material comprises its processed product; The composition and the parts by weight of described compositions are: 100 parts of Radix Et Rhizoma Rhei.
2. a kind of compositions that contains Radix Et Rhizoma Rhei according to claim 1 is characterized in that said composition also can add but is not limited to the raw material of following one or more parts by weight: 50~150 parts of Radix Dichroaes, 50~150 parts of Radix Bupleuri, 50~150 parts of Herba Artemisiae Annuaes; 60~120 parts of Fructus Quisqualis, 60~120 parts of the Radix Pulsatillaes, 60~100 parts of Cortex Fraxinis; 50~150 parts of Rhizoma Imperataes, 50~150 parts of Herba Agrimoniaes, Folium Callicarpae Formosanae 70~110; 50~150 parts of Cortex Moutans, 50~150 parts of Radix Inulaes, 50~150 parts in Radix Glycyrrhizae.
3. according to claim 1 and the 2 described compositionss that contain Radix Et Rhizoma Rhei, it is characterized in that said composition can be prepared into medicine or pharmaceutically acceptable physical aspects such as powder, liquid, paste, granule or capsule.
4. according to claim 1 and 2 described a kind of compositionss that contain Radix Et Rhizoma Rhei, it is characterized in that mixing use by 0.1~10.0% of complete feed weight after compositions is pulverized mix homogeneously; Or said composition processed form such as liquid with water extraction, the content of medicinal liquid Chinese crude drug is: the 1ml medicinal liquid is equivalent to the 1g raw medicinal herbs at least, converts water 10kg~3000kg by 1 Hydrargyri Oxydum Rubrum liquid and freely drinks for the chicken crowd.
CN201110291990A 2011-09-30 2011-09-30 Rhubarb-containing composition and application thereof Pending CN102327329A (en)

Priority Applications (1)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102885914A (en) * 2012-10-30 2013-01-23 天津生机集团股份有限公司 Traditional Chinese medicine oral liquid for treating chicken coccidiosis and preparation method thereof
CN103142766A (en) * 2013-04-02 2013-06-12 河北工程大学 Medicine for controlling coccidiosis in rabbits
CN106344678A (en) * 2016-10-10 2017-01-25 扬中牧乐药业有限公司 Traditional Chinese medicine composition for treating chicken coccidiosis and preparation method thereof
CN106692337A (en) * 2016-12-16 2017-05-24 中科植源康(北京)医学研究所有限公司 Chinese herbal medicine composition for improving animal palatability and preparation method and application thereof in replacing antibiotic, and pig feed composition

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
闫桂云供稿: "临床信息四则", 《畜牧兽医科技信息》 *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102885914A (en) * 2012-10-30 2013-01-23 天津生机集团股份有限公司 Traditional Chinese medicine oral liquid for treating chicken coccidiosis and preparation method thereof
CN103142766A (en) * 2013-04-02 2013-06-12 河北工程大学 Medicine for controlling coccidiosis in rabbits
CN103142766B (en) * 2013-04-02 2014-09-03 河北工程大学 Medicine for controlling coccidiosis in rabbits
CN106344678A (en) * 2016-10-10 2017-01-25 扬中牧乐药业有限公司 Traditional Chinese medicine composition for treating chicken coccidiosis and preparation method thereof
CN106692337A (en) * 2016-12-16 2017-05-24 中科植源康(北京)医学研究所有限公司 Chinese herbal medicine composition for improving animal palatability and preparation method and application thereof in replacing antibiotic, and pig feed composition

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Application publication date: 20120125