CN102327378B - Medicinal composition for preventing and treating porcine myocarditis - Google Patents
Medicinal composition for preventing and treating porcine myocarditis Download PDFInfo
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- CN102327378B CN102327378B CN201110298904.3A CN201110298904A CN102327378B CN 102327378 B CN102327378 B CN 102327378B CN 201110298904 A CN201110298904 A CN 201110298904A CN 102327378 B CN102327378 B CN 102327378B
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Abstract
The invention relates to a medicinal composition for preventing and treating porcine myocarditis. The composition comprises the following raw materials or extracts of the raw materials or chemically-acceptable derivatives of the raw material extracts; and the composition comprises the following raw materials in part by weight: 100 parts of coptis root, 50-180 parts of astragalus, 50-150 parts of dangshen, 50-180 parts of Chinese angelica, 30-180 parts of root of rehmannia and 30-180 parts of liquoric root, on the basis, and further comprises but is not limited to one or more of golden cypress, white paeony root, baical skullcap root, cyrtomium fortune, honeysuckle flower, blackberry lily, dwarf lilyturf root, chinese magnoliavine fruit, cassia twig, Chinese yam and largehead atractylodes rhizome. The composition can be prepared into medicinally or pharmaceutically-acceptable physical forms such as powder, liquids, paste, particles, capsules and the like. The composition can be used for preventing and treating porcine myocarditis and lowering the death rate.
Description
Technical field
The present invention relates to a kind ofly for preventing and treat the pharmaceutical composition of porcine myocarditis, belong to animal and veterinary technical field of Chinese medicines, be mainly used in prevention and treatment porcine myocarditis, reduce mortality rate.
Background technology
In worldwide animal husbandry field, the even dead case of myocarditis causing because of viral infection such as foot and mouth disease increases increasingly, but never has more satisfactory medicine and scheme, is having a strong impact on the sound development of pig industry.In the worker in chemicals field is stymied by, the historical experience of Chinese medicine attracts much attention gradually.
Chinese medicine and compatibility thereof are advocated by conditioning, are regulated every function of body finally to make entirety realize coordinated development, without drug residue, can not develop immunity to drugs; Natural plants and extract component safety thereof, efficient, stable, controlled, utilizing natural plants and Chinese medicine instead of chemical medicine has been world trends.Therefore, research and utilization natural plant and Chinese medicine effectively prevent and treat porcine myocarditis, reduction mortality rate has been endowed more expectation.
Be familiar with myocarditis by Traditional Chinese medical theory, when being the card of evil resistance heart-yang, control when benefiting qi and raising yang, dispelling toxins and dredging collaterals.
Summary of the invention
The present invention aims to provide a kind of for preventing and treat the compositions of porcine myocarditis, and said composition is passed through for prevention and treatment porcine myocarditis, reduced mortality rate.
Of the present invention a kind of for preventing and treat the compositions of porcine myocarditis, the raw material that contains following parts by weight, or the extract of this raw material, or the derivant of the form of chemically can accepting of this raw extract, said raw material comprises its processed product; Composition and the parts by weight of described compositions are: 100 parts of Rhizoma Coptidis, 50～180 parts of the Radixs Astragali, 50～150 parts of Radix Codonopsis, 50～180 parts of Radix Angelicae Sinensis, 30～180 parts, the Radix Rehmanniae, 30～180 parts, Radix Glycyrrhizae.
Can increase as the case may be on the basis of the above but be not limited to one or more components of following parts by weight: 50～150 parts of Cortex Phellodendris, 50～150 parts of the Radix Paeoniae Albas, 30～180 parts of Radix Scutellariaes, 30～180 parts of Rhizoma Osmundae, 60～160 parts of Flos Loniceraes, 60～160 parts of Rhizoma Belamcandae, 30～180 parts of Radix Ophiopogonis, 30～180 parts of Fructus Schisandrae Chinensis, 60～120 parts of Ramulus Cinnamomi, 30～120 parts of Rhizoma Dioscoreaes, 30～120 parts of the Rhizoma Atractylodis Macrocephalaes.
The present composition can be prepared into medicine or the pharmaceutically acceptable physical aspects such as powder, liquid, paste, granule or capsule.Said composition is for prevention and treat porcine myocarditis, reduce mortality rate.
Compositions using method of the present invention and use amount are: after being pulverized and mixed evenly, mixing and use by 0.1～10.0% of complete feed weight; Or said composition is made to the forms such as liquid with water extraction, the content of medicinal liquid Chinese crude drug is: 1ml medicinal liquid is at least equivalent to 1g raw medicinal herbs, is watered 10kg～3000kg freely drinks to swinery by 1 Hydrargyri Oxydum Rubrum liquid.
Rhizoma Coptidis bitter cold, goes heart-fire; The Radix Astragali, Radix Codonopsis yang invigorating are promoted blood circulation, tonification vigour; Radix Angelicae Sinensis, the Radix Rehmanniae etc. nourish heart hemopoietic invigorating the heart-YANG, promote cardiomyopathy repair fast; Radix Glycyrrhizae also has antivirus action.In addition, also can add the product of the heat clearing away YIN nourishing such as Cortex Phellodendri, the Radix Paeoniae Alba, Radix Scutellariae, Rhizoma Osmundae, Flos Lonicerae, Rhizoma Belamcandae, Radix Ophiopogonis, Fructus Schisandrae Chinensis, Ramulus Cinnamomi, Rhizoma Dioscoreae, the Rhizoma Atractylodis Macrocephalae to strengthen the merit of benefiting qi and raising yang, dispelling toxins and dredging collaterals.Therefore, for prevent and treat porcine myocarditis, reduce mortality rate there is positive realistic meaning.
Compositions of the present invention is through inspection, and its poisonous and harmful substance lead (pb), arsenic (As) content all do not exceed " two of Chinese veterinary pharmacopoeias " specified standard.
Detailed description of the invention
Below by embodiment, the present invention is described in further details, these embodiment are only used for illustrating the present invention, do not limit the scope of the invention.
Embodiment 1: 40 parts of Rhizoma Coptidis, 40 parts of the Radixs Astragali, 40 parts of Radix Codonopsis, 30 parts of Radix Angelicae Sinensis, 30 parts, the Radix Rehmanniae, 20 parts, Radix Glycyrrhizae.Above composition is for subsequent use after pulverizing or extracting, and the content of medicinal liquid Chinese crude drug is: 1ml medicinal liquid is at least equivalent to 1g raw medicinal herbs.
Embodiment 2: 40 parts of Rhizoma Coptidis, 30 parts of the Radixs Astragali, 30 parts of Radix Codonopsis, 30 parts of Radix Angelicae Sinensis, 30 parts, the Radix Rehmanniae, 20 parts, Radix Glycyrrhizae, 20 parts of Rhizoma Osmundae.The rear mix homogeneously of above composition pulverizing is for subsequent use or extraction is rear for subsequent use, and the content of medicinal liquid Chinese crude drug is: 1ml medicinal liquid is at least equivalent to 1g raw medicinal herbs.
Embodiment 3: 30 parts of Rhizoma Coptidis, 20 parts of the Radixs Astragali, 20 parts of Radix Codonopsis, 20 parts of Radix Angelicae Sinensis, 20 parts of Radix Ophiopogonis, 30 parts, the Radix Rehmanniae, 20 parts, Radix Glycyrrhizae, 20 parts of Rhizoma Osmundae.The rear mix homogeneously of above composition pulverizing is for subsequent use or extraction is rear for subsequent use, and the content of medicinal liquid Chinese crude drug is: 1ml medicinal liquid is at least equivalent to 1g raw medicinal herbs.
Embodiment 4: 30 parts of Rhizoma Coptidis, 20 parts of the Radixs Astragali, 20 parts of Radix Codonopsis, 20 parts of Radix Angelicae Sinensis, 10 parts, the Radix Rehmanniae, 20 parts of Radix Ophiopogonis, 20 parts of Fructus Schisandrae Chinensis, 20 parts of Rhizoma Osmundae, 20 parts of the Rhizoma Atractylodis Macrocephalaes, 20 parts, Radix Glycyrrhizae.The rear mix homogeneously of above composition pulverizing is for subsequent use or extraction is rear for subsequent use, and the content of medicinal liquid Chinese crude drug is: 1ml medicinal liquid is at least equivalent to 1g raw medicinal herbs.
Part test final report:
a kind of for preventing and treat the test report of the pharmaceutical composition of porcine myocarditis
Select and make a definite diagnosis 173 of pigletss that infect foot and mouth disease and cause myocarditic certain Animal Raising Zone, be divided at random two groups of A, B.Stable breeding, keeps clean, ventilates in time, makes a record.Complete feedstuff, timing is raised, freely drinks water, unified management.A group is test group, adds this extract and is watered 50kg by 1 Hydrargyri Oxydum Rubrum liquid and freely drinks to swinery; B group, for matched group, is made placebo with drinking water; In addition, two groups of A, B are all used in conjunction with fluorine Ben Nikao powder (by specification use) to control secondary infection, test continuous use 6 days simultaneously.By checking that the cardiomyopathy of dead pig judges myocarditic control degree.Above medicine is researched and developed laboratory by Guangdong Zijin Zhengtian Pharmaceutical Co., Ltd., positive sky-Hua Nongxin veterinary drug and is combined and provide.
Table 1 A, two groups for the treatment of comparative test result of B
| Project | A | B |
| The test initial stage (head) | 86 | 87 |
| Test latter stage (head) | 72 | 69 |
| Survival percentage ratio | 83．7% | 79．3% |
| Death toll (head) | 14 | 18 |
| Myocarditis morbidity quantity (head) | 6 | 13 |
| Lethal myocarditis percentage ratio | 42．9% | 72．2% |
As can be seen from Table 1, used the piglets of this kind of compositions treatment, survival rate is apparently higher than matched group and the myocarditis sickness rate of dead pig is starkly lower than matched group.This illustrates that this kind of compositions can, by preventing and treating porcine myocarditis incidence rate and reduce mortality rate, improve survival rate and productivity effect.
Claims (3)
1. for preventing and treat a pharmaceutical composition for porcine myocarditis, it is characterized in that described compositions is made up of the component of following parts by weight: 100 parts of Rhizoma Coptidis, 50～180 parts of the Radixs Astragali, 50～150 parts of Radix Codonopsis, 50～180 parts of Radix Angelicae Sinensis, 30～180 parts, the Radix Rehmanniae, 30～180 parts, Radix Glycyrrhizae.
2. for preventing and treat a pharmaceutical composition for porcine myocarditis, it is characterized in that described compositions is made up of the component of following parts by weight: 40 parts of Rhizoma Coptidis, 30 parts of the Radixs Astragali, 30 parts of Radix Codonopsis, 30 parts of Radix Angelicae Sinensis, 30 parts, the Radix Rehmanniae, 20 parts, Radix Glycyrrhizae, 20 parts of Rhizoma Osmundae.
3. one kind for preventing and treat the pharmaceutical composition of porcine myocarditis, it is characterized in that described compositions is made up of the component of following parts by weight: 30 parts of Rhizoma Coptidis, 20 parts of the Radixs Astragali, 20 parts of Radix Codonopsis, 20 parts of Radix Angelicae Sinensis, 10 parts, the Radix Rehmanniae, 20 parts of Radix Ophiopogonis, 20 parts of Fructus Schisandrae Chinensis, 20 parts of Rhizoma Osmundae, 20 parts of the Rhizoma Atractylodis Macrocephalaes, 20 parts, Radix Glycyrrhizae.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201110298904.3A CN102327378B (en) | 2011-09-29 | 2011-09-29 | Medicinal composition for preventing and treating porcine myocarditis |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201110298904.3A CN102327378B (en) | 2011-09-29 | 2011-09-29 | Medicinal composition for preventing and treating porcine myocarditis |
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| Publication Number | Publication Date |
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| CN102327378A CN102327378A (en) | 2012-01-25 |
| CN102327378B true CN102327378B (en) | 2014-07-09 |
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Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102697946B (en) * | 2012-05-08 | 2014-03-26 | 广州市和生堂动物药业有限公司 | Medicine for controlling sow breeding difficulty and improving productivity |
| CN103432457B (en) * | 2013-08-19 | 2014-10-22 | 马世爱 | Chinese medicine preparation for treating viral myocarditis |
| CN104147346B (en) * | 2014-07-28 | 2018-06-05 | 山东中医药大学附属医院 | It is a kind of to treat the anginal Chinese medicine compound prescription of coronary artery diffusivity lesion |
| CN105983050A (en) * | 2015-02-02 | 2016-10-05 | 北京大北农动物保健科技有限责任公司 | Pharmaceutical composition of radix astragali pulse-activating drink, preparation method of pharmaceutical composition and feed |
| CN105535198B (en) * | 2016-01-29 | 2020-03-31 | 青岛信诺邦生物科技有限公司 | Traditional Chinese medicine composition for treating poultry hydropericardium |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1136444A (en) * | 1995-05-22 | 1996-11-27 | 王希亚 | Medicine for curing coronary heart disease |
| CN1559470A (en) * | 2004-03-01 | 2005-01-05 | 王原成 | Chinese patent drug for livestock |
| CN101181505A (en) * | 2007-12-05 | 2008-05-21 | 荣玉明 | Chinese medicine prescription for cardiac disease as well as manufacturing method |
| CN101683116A (en) * | 2008-09-23 | 2010-03-31 | 张松灿 | Pure traditional Chinese medicine feed additive |
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- 2011-09-29 CN CN201110298904.3A patent/CN102327378B/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1136444A (en) * | 1995-05-22 | 1996-11-27 | 王希亚 | Medicine for curing coronary heart disease |
| CN1559470A (en) * | 2004-03-01 | 2005-01-05 | 王原成 | Chinese patent drug for livestock |
| CN101181505A (en) * | 2007-12-05 | 2008-05-21 | 荣玉明 | Chinese medicine prescription for cardiac disease as well as manufacturing method |
| CN101683116A (en) * | 2008-09-23 | 2010-03-31 | 张松灿 | Pure traditional Chinese medicine feed additive |
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