CN102327378A - Medicinal composition for preventing and treating porcine myocarditis - Google Patents
Medicinal composition for preventing and treating porcine myocarditis Download PDFInfo
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- CN102327378A CN102327378A CN201110298904A CN201110298904A CN102327378A CN 102327378 A CN102327378 A CN 102327378A CN 201110298904 A CN201110298904 A CN 201110298904A CN 201110298904 A CN201110298904 A CN 201110298904A CN 102327378 A CN102327378 A CN 102327378A
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Abstract
The invention relates to a medicinal composition for preventing and treating porcine myocarditis. The composition comprises the following raw materials or extracts of the raw materials or chemically-acceptable derivatives of the raw material extracts; and the composition comprises the following raw materials in part by weight: 100 parts of coptis root, 50-180 parts of astragalus, 50-150 parts of dangshen, 50-180 parts of Chinese angelica, 30-180 parts of root of rehmannia and 30-180 parts of liquoric root, on the basis, and further comprises but is not limited to one or more of golden cypress, white paeony root, baical skullcap root, cyrtomium fortune, honeysuckle flower, blackberry lily, dwarf lilyturf root, chinese magnoliavine fruit, cassia twig, Chinese yam and largehead atractylodes rhizome. The composition can be prepared into medicinally or pharmaceutically-acceptable physical forms such as powder, liquids, paste, particles, capsules and the like. The composition can be used for preventing and treating porcine myocarditis and lowering the death rate.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition that is used to prevent and treat Cor Sus domestica myositis, belong to the animal and veterinary technical field of Chinese medicines, be mainly used in prevention and treatment Cor Sus domestica myositis, reduce mortality rate.
Background technology
In worldwide animal husbandry field, the myocarditis even the dead case that cause because of viral infection such as foot and mouth disease increase day by day, but never have more satisfactory medicine and scheme, are having a strong impact on the sound development of pig industry.In the worker in chemicals field was stymied by, the historical experience of Chinese medicine caused people's attention gradually.
Chinese medicine and compatibility thereof advocate finally to make the whole coordinated development that realizes through conditioning, each item function of regulating body, no drug residue, can not develop immunity to drugs; Natural plants and extract component safety thereof, efficient, stable, controlled, utilizing natural plants and Chinese medicine instead of chemical medicine has been world trends.Therefore, research and utilization natural plant and Chinese medicine effectively prevent and treat Cor Sus domestica myositis, the reduction mortality rate has been endowed more expectation.
Be familiar with myocarditis with Traditional Chinese medical theory,, control when benefiting qi and raising yang, dispelling toxins and dredging collaterals when the card that is evil resistance heart-yang.
Summary of the invention
The present invention aims to provide a kind of compositions that is used to prevent and treat Cor Sus domestica myositis, and said composition is through being used for prevention and treatment Cor Sus domestica myositis, reducing mortality rate.
A kind of compositions that is used to prevent and treat Cor Sus domestica myositis of the present invention contains the raw material of following parts by weight, the perhaps extract of this raw material, and the perhaps derivant of the form of chemically can accepting of this raw extract, said raw material comprises its processed product; The composition and the parts by weight of described compositions are: 100 parts of Rhizoma Coptidis, 50～180 parts of the Radixs Astragali, 50～150 parts of Radix Codonopsis, 50～180 parts of Radix Angelicae Sinensis, 30～180 parts in the Radix Rehmanniae, 30～180 parts in Radix Glycyrrhizae.
Can increase as the case may be on the basis of the above but be not limited to one or more components of following parts by weight: 50～150 parts of Cortex Phellodendris, 50～150 parts of the Radix Paeoniae Albas, 30～180 parts of Radix Scutellariaes; 30～180 parts of Rhizoma Osmundae, 60～160 parts of Flos Loniceraes, 60～160 parts of Rhizoma Belamcandae; 30～180 parts of Radix Ophiopogonis, 30～180 parts of Fructus Schisandrae Chinensis, 60～120 parts of Ramulus Cinnamomi; 30～120 parts of Rhizoma Dioscoreaes, 30～120 parts of the Rhizoma Atractylodis Macrocephalaes.
The present composition can be prepared into medicine or pharmaceutically acceptable physical aspects such as powder, liquid, paste, granule or capsule.Said composition is used for prevention and treatment Cor Sus domestica myositis, reduces mortality rate.
Compositions method for using according to the invention and use amount are: press 0.1～10.0% of complete feed weight behind the pulverizing mix homogeneously and mix use; Or said composition processed form such as liquid with water extraction, the content of medicinal liquid Chinese crude drug is: the 1ml medicinal liquid is equivalent to the 1g raw medicinal herbs at least, converts water 10kg～3000kg by 1 Hydrargyri Oxydum Rubrum liquid and freely drinks for swinery.
The Rhizoma Coptidis bitter cold is gone heart-fire; The Radix Astragali, Radix Codonopsis yang invigorating are promoted blood circulation, tonification vigour; Radix Angelicae Sinensis, the Radix Rehmanniae etc. nourish heart the hemopoietic invigorating the heart-YANG, promote cardiomyopathy to repair fast; Radix Glycyrrhizae also has antivirus action.The article that in addition, also can add heat clearing away YIN nourishing such as Cortex Phellodendri, the Radix Paeoniae Alba, Radix Scutellariae, Rhizoma Osmundae, Flos Lonicerae, Rhizoma Belamcandae, Radix Ophiopogonis, Fructus Schisandrae Chinensis, Ramulus Cinnamomi, Rhizoma Dioscoreae, the Rhizoma Atractylodis Macrocephalae are to strengthen the merit of benefiting qi and raising yang, dispelling toxins and dredging collaterals.Therefore, be used for prevention and treatment Cor Sus domestica myositis, reduce mortality rate and have active operation significance.
Compositions of the present invention is through check, and its poisonous and harmful substance plumbous (pb), arsenic (As) content all do not surpass " two ones of Chinese veterinary drug allusion quotations " specified standard.
The specific embodiment
Through embodiment the present invention is explained further details below, these embodiment only are used for explaining the present invention, do not limit the scope of the invention.
Embodiment 1: 40 parts of Rhizoma Coptidis, 40 parts of the Radixs Astragali, 40 parts of Radix Codonopsis, 30 parts of Radix Angelicae Sinensis, 30 parts in the Radix Rehmanniae, 20 parts in Radix Glycyrrhizae.It is subsequent use that the back is pulverized or extracted to above composition, and the content of medicinal liquid Chinese crude drug is: the 1ml medicinal liquid is equivalent to the 1g raw medicinal herbs at least.
Embodiment 2: 40 parts of Rhizoma Coptidis, 30 parts of the Radixs Astragali, 30 parts of Radix Codonopsis, 30 parts of Radix Angelicae Sinensis, 30 parts in the Radix Rehmanniae, 20 parts in Radix Glycyrrhizae, 20 parts of Rhizoma Osmundae.Above composition pulverizing back mix homogeneously is subsequent use or the extraction back is subsequent use, and the content of medicinal liquid Chinese crude drug is: the 1ml medicinal liquid is equivalent to the 1g raw medicinal herbs at least.
Embodiment 3: 30 parts of Rhizoma Coptidis, 20 parts of the Radixs Astragali, 20 parts of Radix Codonopsis, 20 parts of Radix Angelicae Sinensis, 20 parts of Radix Ophiopogonis, 30 parts in the Radix Rehmanniae, 20 parts in Radix Glycyrrhizae, 20 parts of Rhizoma Osmundae.Above composition pulverizing back mix homogeneously is subsequent use or the extraction back is subsequent use, and the content of medicinal liquid Chinese crude drug is: the 1ml medicinal liquid is equivalent to the 1g raw medicinal herbs at least.
Embodiment 4: 30 parts of Rhizoma Coptidis, 20 parts of the Radixs Astragali, 20 parts of Radix Codonopsis, 20 parts of Radix Angelicae Sinensis, 10 parts in the Radix Rehmanniae, 20 parts of Radix Ophiopogonis, 20 parts of Fructus Schisandrae Chinensis, 20 parts of Rhizoma Osmundae, 20 parts of the Rhizoma Atractylodis Macrocephalaes, 20 parts in Radix Glycyrrhizae.Above composition pulverizing back mix homogeneously is subsequent use or the extraction back is subsequent use, and the content of medicinal liquid Chinese crude drug is: the 1ml medicinal liquid is equivalent to the 1g raw medicinal herbs at least.
The part test final report:
A kind of test report that is used to prevent and treat the pharmaceutical composition of Cor Sus domestica myositis
Select for use make a definite diagnosis infect foot and mouth disease cause myocarditic certain culture 173 of the pigletss of sub-district, be divided into two groups of A, B at random.Stable breeding keeps clean, in time ventilates, and carries out record.Complete feedstuff is regularly raised, and freely drinks water unified management.A group is test group, adds this extract and converts water 50kg by 1 Hydrargyri Oxydum Rubrum liquid and freely drink for swinery; The B group is made placebo for matched group with drinking water; In addition, A, B all are used fluorine Ben Nikao powder (by specification use) with the control secondary infection, test continuous use 6 days for two groups simultaneously.Cardiomyopathy through checking dead pig is judged myocarditic control degree.Above medicine is researched and developed laboratory by Guangdong Zijin positive day pharmaceutcal corporation, Ltd, positive sky-Hua Nongxin veterinary drug and is united and provide.
Table 1 A, two groups of treatments of B comparative test result
| Project | A | B |
| The test initial stage (head) | 86 | 87 |
| Test latter stage (head) | 72 | 69 |
| Survival percentage ratio | 83．7% | 79．3% |
| Death toll (head) | 14 | 18 |
| Myocarditis morbidity quantity (head) | 6 | 13 |
| Lethal myocarditis percentage ratio | 42．9% | 72．2% |
Can be found out by table 1, use the piglets of this kind combination treatment, survival rate is apparently higher than matched group and the myocarditis sickness rate of dead pig is starkly lower than matched group.This this kind of explanation compositions can reduce mortality rate through prevention and treatment Cor Sus domestica myositis incidence rate, improves survival rate and productivity effect.
Claims (4)
1. pharmaceutical composition that is used to prevent and treat Cor Sus domestica myositis; It is characterized in that said compositions contains the raw material of following parts by weight; The perhaps extract of this raw material, the perhaps derivant of the form of chemically can accepting of this raw extract, said raw material comprises its processed product; The composition and the parts by weight of described compositions are: 100 parts of Rhizoma Coptidis, 50～180 parts of the Radixs Astragali, 50～150 parts of Radix Codonopsis, 50～180 parts of Radix Angelicae Sinensis, 30～180 parts in the Radix Rehmanniae, 30～180 parts in Radix Glycyrrhizae.
2. according to the said a kind of pharmaceutical composition that is used to prevent and treat Cor Sus domestica myositis of claim 1, it is characterized in that said composition also can add but is not limited to the raw material of following one or more parts by weight: 50～150 parts of Cortex Phellodendris, 50～150 parts of the Radix Paeoniae Albas; 30～180 parts of Radix Scutellariaes, 30～180 parts of Rhizoma Osmundae, 60～160 parts of Flos Loniceraes; 60～160 parts of Rhizoma Belamcandae, 30～180 parts of Radix Ophiopogonis, 30～180 parts of Fructus Schisandrae Chinensis; 60～120 parts of Ramulus Cinnamomi, 30～120 parts of Rhizoma Dioscoreaes, 30～120 parts of the Rhizoma Atractylodis Macrocephalaes.
3. according to claim 1 and 2 described a kind of pharmaceutical compositions that are used to prevent and treat Cor Sus domestica myositis, it is characterized in that said composition can be prepared into medicine or pharmaceutically acceptable physical aspects such as powder, liquid, paste, granule or capsule.
4. according to claim 1 and 2 described a kind of pharmaceutical compositions that are used to prevent and treat Cor Sus domestica myositis, it is characterized in that the method for using of said compositions and use amount are: press 0.1～10.0% of complete feed weight behind the compositions pulverizing mix homogeneously and mix use; Or said composition processed form such as liquid with water extraction, the content of medicinal liquid Chinese crude drug is: the 1ml medicinal liquid is equivalent to the 1g raw medicinal herbs at least, converts water 10kg～3000kg by 1 Hydrargyri Oxydum Rubrum liquid and freely drinks for swinery.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201110298904.3A CN102327378B (en) | 2011-09-29 | 2011-09-29 | Medicinal composition for preventing and treating porcine myocarditis |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201110298904.3A CN102327378B (en) | 2011-09-29 | 2011-09-29 | Medicinal composition for preventing and treating porcine myocarditis |
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| CN102327378A true CN102327378A (en) | 2012-01-25 |
| CN102327378B CN102327378B (en) | 2014-07-09 |
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| CN201110298904.3A Expired - Fee Related CN102327378B (en) | 2011-09-29 | 2011-09-29 | Medicinal composition for preventing and treating porcine myocarditis |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102697946A (en) * | 2012-05-08 | 2012-10-03 | 广州市和生堂动物药业有限公司 | Medicine for controlling sow breeding difficulty and improving productivity |
| CN103432457A (en) * | 2013-08-19 | 2013-12-11 | 马世爱 | Chinese medicine preparation for treating viral myocarditis |
| CN104147346A (en) * | 2014-07-28 | 2014-11-19 | 山东中医药大学附属医院 | Traditional Chinese medicinal compound for treating coronary diffuse lesion angina |
| CN105535198A (en) * | 2016-01-29 | 2016-05-04 | 青岛信诺邦生物科技有限公司 | Traditional Chinese medicine composition for treating poultry hydropericardium |
| CN105983050A (en) * | 2015-02-02 | 2016-10-05 | 北京大北农动物保健科技有限责任公司 | Pharmaceutical composition of radix astragali pulse-activating drink, preparation method of pharmaceutical composition and feed |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1136444A (en) * | 1995-05-22 | 1996-11-27 | 王希亚 | Medicine for curing coronary heart disease |
| CN1559470A (en) * | 2004-03-01 | 2005-01-05 | 王原成 | Chinese patent drug for livestock |
| CN101181505A (en) * | 2007-12-05 | 2008-05-21 | 荣玉明 | Chinese medicine prescription for cardiac disease as well as manufacturing method |
| CN101683116A (en) * | 2008-09-23 | 2010-03-31 | 张松灿 | Pure traditional Chinese medicine feed additive |
-
2011
- 2011-09-29 CN CN201110298904.3A patent/CN102327378B/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1136444A (en) * | 1995-05-22 | 1996-11-27 | 王希亚 | Medicine for curing coronary heart disease |
| CN1559470A (en) * | 2004-03-01 | 2005-01-05 | 王原成 | Chinese patent drug for livestock |
| CN101181505A (en) * | 2007-12-05 | 2008-05-21 | 荣玉明 | Chinese medicine prescription for cardiac disease as well as manufacturing method |
| CN101683116A (en) * | 2008-09-23 | 2010-03-31 | 张松灿 | Pure traditional Chinese medicine feed additive |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102697946A (en) * | 2012-05-08 | 2012-10-03 | 广州市和生堂动物药业有限公司 | Medicine for controlling sow breeding difficulty and improving productivity |
| CN102697946B (en) * | 2012-05-08 | 2014-03-26 | 广州市和生堂动物药业有限公司 | Medicine for controlling sow breeding difficulty and improving productivity |
| CN103432457A (en) * | 2013-08-19 | 2013-12-11 | 马世爱 | Chinese medicine preparation for treating viral myocarditis |
| CN103432457B (en) * | 2013-08-19 | 2014-10-22 | 马世爱 | Chinese medicine preparation for treating viral myocarditis |
| CN104147346A (en) * | 2014-07-28 | 2014-11-19 | 山东中医药大学附属医院 | Traditional Chinese medicinal compound for treating coronary diffuse lesion angina |
| CN105983050A (en) * | 2015-02-02 | 2016-10-05 | 北京大北农动物保健科技有限责任公司 | Pharmaceutical composition of radix astragali pulse-activating drink, preparation method of pharmaceutical composition and feed |
| CN105535198A (en) * | 2016-01-29 | 2016-05-04 | 青岛信诺邦生物科技有限公司 | Traditional Chinese medicine composition for treating poultry hydropericardium |
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| CN102327378B (en) | 2014-07-09 |
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