CN102697946B - Medicine for controlling sow breeding difficulty and improving productivity - Google Patents

Medicine for controlling sow breeding difficulty and improving productivity Download PDF

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CN102697946B
CN102697946B CN201210140134.4A CN201210140134A CN102697946B CN 102697946 B CN102697946 B CN 102697946B CN 201210140134 A CN201210140134 A CN 201210140134A CN 102697946 B CN102697946 B CN 102697946B
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sow
medicine
radix
breeding difficulty
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CN102697946A (en
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郑铁锁
萧子慈
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GUANGZHOU HESHENGTANG ANIMAL PHARMACEUTICAL CO Ltd
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GUANGZHOU HESHENGTANG ANIMAL PHARMACEUTICAL CO Ltd
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Abstract

The invention discloses a medicine for controlling sow breeding difficulty and improving productivity. The medicine comprises the components in parts by weight as follows: 10 to 30 parts of glabrous sarcandra glabrous herb, 20 to 60 parts of radix fici simplicissimae, 12 to 30 parts of eucommia ulmoides oliv, 15 to 35 parts of radix scutellariae, 10 to 40 parts of bighead atractylodes rhizome, 10 to 30 parts of radix rehmanniae preparata, 5 to 20 parts of liquorice, 10 to 30 parts of isatis root, and 15 to 35 parts of glossy privet fruit. According to the invention, the traditional Chinese medicines replace antibiotics and antiviral drugs to control the sow breeding difficulty and improve the productivity of the sow; and a medicine with high efficiency and without residues and medicine resistance and side effect is provided for the pig industry. The medicine disclosed by the invention can be widely used for controlling the sow breeding difficulty and improving the productivity of the sow, as well as promoting the sustainable health development of the pig industry.

Description

A kind of medicine of preventing and treating sow breeding difficulty, improving fertility performance
Technical field
The present invention relates to a kind of veterinary drug, be specifically related to a kind of medicine of preventing and treating sow breeding difficulty, improving fertility performance.
Background technology
At home and abroad, there is generation in various degree in every place of raising pigs and has the Reproduction Disorder of sow.According to some countries, the loss that sow miscarriage, stillbirth etc. cause accounts for 1/4th of suckling pig.China in different regions, the loss that causes of different pig farm, different year is not quite identical, but loss piglet is comparatively common 1/4th left and right, and indivedual local piglet loss rates reach 40%, even 80% above person also has generation, has often caused the piglet tomography in a period.The loss because of sow breeding difficulty disease, pig industry being caused is as can be seen here very huge.
The cause of disease that causes sow breeding difficulty disease generally can be divided into the non-infectious and large class of infectiousness two.The noninfectious cause of disease mainly refers to environment, nutrition, factor that stress aspect, but this is not the main cause that causes sow breeding difficulty disease.The communicable cause of disease refers to by special pathogen caused, be the main cause that causes sow breeding difficulty, known that the virus that causes sow breeding difficulty has parvovirus (PPV), pseudorabies virus (PRV), Japanese B encephalitis virus (JEV), swine fever virus (HCV), pig breeding and respiratory complication (PRRS), influenza virus (ISV), adenovirus (MAV) etc. at present.Aspect bacteria pathogeny, there are Brucella, Listeria monocytogenes, corynebacterium, Streptococcus suis, bacillus rhusiopathiae suis, campylobacter fetus etc.Some parasitic disease occur as arch insect infection, leptospira, chlamydia, eperythrozoon suis etc. also all can cause breeding difficulty.
Sow breeding difficulty main manifestations is that replacement gilt reaches after sexual maturity, body maturation non-estrus or sow (comprising primiparity and multiparity) postweaning estrus interval extends, non-estrus; Sow Repeat breeding; In-pig embryonic death, miscarriage, the weak tire of product, mummy tire or stillborn fetus, sow generation metritis, mastitis, agalactia syndrome etc.Breeding difficulty is to cause sow to eliminate topmost factor, also makes the sow state in non-gestation, non-suckling in a long time, has had a strong impact on the economic benefit of large-scale pig farm.
At present, for sow Reproduction Disorder, also well do not prevent and Therapeutic Method, be mainly by strengthening feeding and management, immune vaccine, use antibiotic, antiviral, hormone medicine prevents and treat, but effect is unsatisfactory, or often there is pig breeding dysfunction disease.
Summary of the invention
The object of the present invention is to provide a kind of medicine of preventing and treating sow breeding difficulty, improving fertility performance, by Chinese medicine substitute antibiotics and antiviral treatment sow breeding difficulty, for pig industry a kind of efficient, noresidue is provided, without drug resistance and the medicine that has no side effect.
For achieving the above object, the present invention adopts following technical scheme:
A kind of medicine of preventing and treating sow breeding difficulty, improving fertility performance, the parts by weight of its each component consist of: Herba Pileae Scriptae 10-30 part, Herba Fici Simplicissimae 20-60 part, Cortex Eucommiae 12-30 part, Radix Scutellariae 15-35 part, Rhizoma Atractylodis Macrocephalae 10-40 part, Radix Rehmanniae Preparata 10-30 part, Radix Glycyrrhizae 5-20 part, Radix Isatidis 10-30 part, Fructus Ligustri Lucidi 15-35 part.
The parts by weight of this each component of medicine consist of: Herba Pileae Scriptae 15-20 part, Herba Fici Simplicissimae 30-50 part, Cortex Eucommiae 15-18 part, Radix Scutellariae 20-30 part, Rhizoma Atractylodis Macrocephalae 25-30 part, Radix Rehmanniae Preparata 20-25 part, Radix Glycyrrhizae 10-15 part, Radix Isatidis 20-25 part, Fructus Ligustri Lucidi 20-30 part.
Described medicine can be made powder or granule.
Powder preparation method: Herba Pileae Scriptae, Herba Fici Simplicissimae, the Cortex Eucommiae, Radix Scutellariae, the Rhizoma Atractylodis Macrocephalae, Radix Rehmanniae Preparata, Radix Isatidis, Fructus Ligustri Lucidi and Radix Glycyrrhizae are taken in proportion, pulverize, cross 100-300 mesh sieve, mix homogeneously, subpackage.
Process for producing granula: add 8-12 times of purified water to soak 2-5 hour Herba Pileae Scriptae, Herba Fici Simplicissimae, the Cortex Eucommiae, Radix Scutellariae, the Rhizoma Atractylodis Macrocephalae, Radix Rehmanniae Preparata, Radix Isatidis, Fructus Ligustri Lucidi and Radix Glycyrrhizae, extract 2 times, extract 2-3 hour the 1st time, extract 1-2 hour the 2nd time, high speed centrifugation, is concentrated to relative density 1.05-1.25 by medicinal liquid, add adjuvant, dry, granulate, subpackage.Putting shady and cool dry place preserves.
Know-why of the present invention: Herba Pileae Scriptae: bitter, pungent, flat, GUIXIN, Liver Channel, clearing away heat and cooling blood, the speckle removing of invigorating blood circulation, dispelling wind and removing obstruction in the collateral, cure mainly dysentery, influenza etc.
Herba Fici Simplicissimae: sweet, tepor, returns spleen, lung meridian.Invigorating the spleen for eliminating dampness, promoting the circulation of QI and reducing phlegm, relaxing muscles and tendons and activating QI and blood in the collateral.For insufficiency of the spleen edema; Lack of appetite is unable; Cough; Puerperal agalactia; Rheumatic arthralgia; Edema; Hepatitis; Traumatic injury
The Cortex Eucommiae: sweet, micro-pungent, temperature.Return liver, kidney channel.Invigorating the liver and kidney, bone and muscle strengthening, antiabortive.For lumbago due to renal deficiency, rheumatic arthralgia, frequent fetal movement.
Radix Scutellariae: hardship, cold.Return lung, gallbladder, large intestine channel.Heat clearing and damp drying, eliminating fire and detoxication, antiabortive.For damp-heat dysentery, cough, skin ulcer Huang, jaundice and frequent fetal movement.
The Rhizoma Atractylodis Macrocephalae: sweet, bitter, temperature.Return spleen, stomach warp.Spleen reinforcing stomach function regulating, dampness diuretic, strengthening superficial resistance to stop perspiration, antiabortive.For diarrhea due to hypofunction of the spleen, edema, spontaneous perspiration, frequent fetal movement.
Radix Rehmanniae Preparata: sweet, be slightly cold.GUIXIN, liver, kidney channel.Nourishing YIN and supplementing blood, beneficial essence is filled out marrow.For syndrome of deficiency of blood, deficiency of kidney yin.
Radix Glycyrrhizae: sweet, flat.Return 12 warps.Invigorating the spleen and replenishing QI, expelling phlegm for arresting cough, and middle emergency, removing toxic substances, the mediation property of medicine.For weakness of the spleen and stomach, cough with asthma, sore and toxic, laryngopharynx swelling and pain, poisoning.
Radix Isatidis: hardship, cold.GUIXIN, lung meridian.Heat-clearing and toxic substances removing, removing heat from blood, sore-throat relieving.For diseases caused by exogenous pathogenic factor pathogenic wind-warm epidemic disease, pyretic toxicity ecchymosis, dysentery, laryngopharynx swelling and pain.
Fructus Ligustri Lucidi: sweet, micro-hardship, flat.Return liver, kidney channel.Nourishing the liver and kidney, strengthening waist and knee.For the hepatic and renal YIN deficiency, fever due to yin deficiency.
Chinese medicine composition of the present invention, take Herba Pileae Scriptae, Radix Isatidis, Radix Scutellariae is principal agent, heat-clearing and toxic substances removing, removing heat from blood; Herba Fici Simplicissimae, the Cortex Eucommiae, the Rhizoma Atractylodis Macrocephalae are ministerial drug, drying damp and strengthening spleen, antiabortive; Radix Rehmanniae Preparata, Fructus Ligustri Lucidi are adjuvant drug, nourishing the liver and kidney, nourishing YIN and supplementing blood; Radix Glycyrrhizae is for making medicine, is in harmonious proportion the property of medicine.All medicines above, jointly bring into play eliminating pathogenic factor for supporting vital QI, promote oestrus of sow, prevent miscarriage antiabortive, strengthen the effects such as milking sow lactation ability.
The present invention compares and has following advantage with other products:
1, the present invention is directed to and cause sow common factors and symptom science compatibility, in compositions, contain the various active materials such as polysaccharide, saponin, organic acid, alkaloid, synergism performance drug effect, there is heat-clearing and toxic substances removing, invigorating the spleen and replenishing QI, nourishing the liver and kidney, bone and muscle strengthening, nourish blood enrich blood, anti-stress, enhancing human body immunity function and prevent the effects such as reproductive system disease, to prevention and treatment sow breeding difficulty, improve sow production performance and have good effect.
2,, to farrowing sow not, promoting the sexual maturity of animals and promoting gravidity, improves conception rate.To farrowing sow, the preventing miscarriage of preventing miscarriage, prevents miscarriage or stillborn fetus or mummy tire, and protection intestinal mucosa, strengthens intestinal protective barrier, improves the mobility of small intestinal, prevents constipation.For nursing sow, increase serum colostrum protein, lactose, antibody and growth factor content, the generation of control mastitis, agalactia syndrome and metritis disease, strengthens milking capacity, improve milk quality and ablactational baby pig body weight etc., avoid piglet that diarrhoea and dead occurs.
The specific embodiment
Embodiment 1:
A kind of medicine of preventing and treating sow breeding difficulty, improving fertility performance, the parts by weight of its each component consist of: Herba Pileae Scriptae 15, Herba Fici Simplicissimae 50, the Cortex Eucommiae 18, Radix Scutellariae 20, the Rhizoma Atractylodis Macrocephalae 30, Radix Rehmanniae Preparata 25, Radix Glycyrrhizae 10, Radix Isatidis 25, Fructus Ligustri Lucidi 30, through pulverizing, make powder.
Preparation method: above-mentioned Chinese medicine is pulverized, crossed 300 mesh sieves, mix homogeneously, subpackage, obtains.
Example 2:
A kind of medicine of preventing and treating sow breeding difficulty, improving fertility performance, the parts by weight of its each component consist of: by Herba Pileae Scriptae 20, Herba Fici Simplicissimae 30, the Cortex Eucommiae 15, Radix Scutellariae 30, the Rhizoma Atractylodis Macrocephalae 25, Radix Rehmanniae Preparata 20, Radix Glycyrrhizae 15, Radix Isatidis 25, Fructus Ligustri Lucidi 20, through extracting, concentrate, being dried granulation agent.
Preparation method: add 10 times of purified water to soak 3 hours above-mentioned Chinese crude drug, 100 ℃ are extracted 2 times, extract 2 hours for the 1st time, extract 1.5 hours for the 2nd time, high speed centrifugation is removed precipitation, cryogenic vacuum is concentrated into 1: 1 (medicinal liquid: medical material), concentrated medicament relative density is 1.10 (80 ℃ of surveys), adds glucose and cyclodextrin, dry, granulation, 1g is equivalent to containing crude drug 2g, subpackage.
Test determination result of use:
Test 1
Pig farm, Sihui, Guangdong, 300 of the numerous sows of energy, pig farm boss reflection, has part sow to be difficult for becoming pregnant, and easily miscarries, or give birth to weak tire, stillborn fetus after becoming pregnant in mid trimester of pregnancy or later stage, gives birth to piglet and easily suffers from diarrhoea, and survival rate is low, to pig farm, causes heavy losses.After going and finding out what's going on, advise that pig farm boss uses the Chinese medicinal composition granules provided by the invention whole audience sow of feeding, the addition according to 0.5% adds in feedstuff, mixed feeding, and first trimester is used 1 time every month, each 10 days.By 0.2% addition, feed every month later, after use, obtain remarkable result, after 3 months, no longer include sow and miscarry, the piglet survival ratio that after 6 months, sow gives birth to reaches 96%, seldom has suckling pig to suffer from diarrhoea, and after wean, piglet is strong, fur is ruddy, light.
Test 2
In Guangdong, a plurality of sows field, Guangxi, choose expected date of confinement, parity (3-5 tire), body condition is close, the length that is in a good state of health is white * Yorkshire sow, totally 300, be divided at random two groups, test group, at the sow gestation initial stage, feed and be added with Chinese medicine composition composition powders provided by the invention, addition is 0.5%, be that 5kg Chinese powder medicine adds in 1000kg feedstuff, matched group, do not add Chinese powder medicine of the present invention, other is identical with test group, be used in conjunction 10 days, regularly use 10 days every month later, just before giving birth front 10 days of sow and 10 days puerperal re-use, weanling sow is used 7 days, after conceived, using method is with noted earlier, it uses 3 parity, during each piglet 21 age in days, wean.Prevention sow Reproduction Disorder and raising sow production performance are obtained to obvious preventive effect.Test data adopts SPSS13.0 software to carry out T check, and result represents with meansigma methods.The results are shown in Table 1
The effect of table 1 Chinese medicine composition prevention sow breeding difficulty, raising fertility performance
Figure BSA00000713350900051
Figure BSA00000713350900061
Test 3
A plurality of sows field in Guangdong Province, choose expected date of confinement, parity (3-5 tire), body condition close, the length that is in a good state of health is white * Yorkshire sow, totally 500, be divided at random two groups, test group, sow, within antenatal 1 week, starting to feed is added with Chinese medicinal composition granules provided by the invention, and addition is 0.5%, and 5kg Chinese medicine granules adds in 1000kg feedstuff, be used in conjunction 14 days, matched group, does not add Chinese powder medicine of the present invention, within antenatal 7 days, in feedstuff, adds florfenicol, add tylosin 7 days puerperal in feedstuff, and other is identical with test group.Piglet is weaned when 28 age in days.Chinese powder medicine of the present invention is obtained obvious preventive effect to prevention sow Reproduction Disorder and raising sow production performance.Test data adopts SPSS13.0 software to carry out T check, and result represents with meansigma methods.The results are shown in Table 2
The effect of a table 2 Chinese medicine composition prevention sow breeding difficulty, raising fertility performance
Above result in clinical application shows, Chinese medicine composition provided by the invention is to control sow mastitis and metritis, increase sow lactation amount, raising piglet survival rate and piglet birth are heavy and weaning weight, reduction prevention of sow constipation rate, abortion ratio, piglet diarrhea rate, the postweaning estrus of shortening sow are become pregnant interval time, demonstrates there is to significant effect control sow breeding difficulty, raising sow production performance aspect.

Claims (1)

1. prevent and treat sow breeding difficulty for one kind, improve the medicine of fertility performance, it is characterized in that: this medicine is made by following methods: the parts by weight of its each component consist of: by Herba Pileae Scriptae 20, Herba Fici Simplicissimae 30, the Cortex Eucommiae 15, Radix Scutellariae 30, the Rhizoma Atractylodis Macrocephalae 25, Radix Rehmanniae Preparata 20, Radix Glycyrrhizae 15, Radix Isatidis 25, Fructus Ligustri Lucidi 20, add 10 times of purified water to soak 3 hours above-mentioned Chinese crude drug, 100 ℃ are extracted 2 times, extract 2 hours for the 1st time, extract 1.5 hours for the 2nd time, high speed centrifugation is removed precipitation, cryogenic vacuum is concentrated into medicinal liquid and medical material ratio is 1:1, concentrated medicament is 1.10 80 ℃ of relative densities, add glucose and cyclodextrin, dry, granulation, 1g is equivalent to containing crude drug 2g, subpackage.
CN201210140134.4A 2012-05-08 2012-05-08 Medicine for controlling sow breeding difficulty and improving productivity Expired - Fee Related CN102697946B (en)

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CN102987116B (en) * 2012-10-08 2014-01-08 安徽长风农牧科技有限公司 Feed additive for improving reproductive performance of multiparous sow
CN105379979A (en) * 2015-11-22 2016-03-09 衡阳市富矿饲料添加剂有限公司 Chinese herbal medicine additive capable of prolonging productive life of breeding sow and preparation method thereof
CN109924344A (en) * 2017-12-15 2019-06-25 颜小淋 A kind of lactating sow feed and its feeding method

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