CN101543589B - Compound pharmaceutical composition for curing virus diseases of animals and preparation method thereof - Google Patents
Compound pharmaceutical composition for curing virus diseases of animals and preparation method thereof Download PDFInfo
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- CN101543589B CN101543589B CN2008101027468A CN200810102746A CN101543589B CN 101543589 B CN101543589 B CN 101543589B CN 2008101027468 A CN2008101027468 A CN 2008101027468A CN 200810102746 A CN200810102746 A CN 200810102746A CN 101543589 B CN101543589 B CN 101543589B
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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Abstract
The invention provides a high-efficiency, rapid and safe compound pharmaceutical composition for curing virus diseases of animals and a preparation method thereof. The compound pharmaceutical composition comprises the following components of forsythia fruit, isatis root, bamboo leaf, scutellaria root, honeysuckle flower, isatis leaf, milkvetch root, longspur epimedium, glossy privet fruit, dried rehmannia root, red sage root, chuanxiong rhizome, dark plum, peppergrass, tendril-leaved fritillary bulb, tangerine peel, lilyturf root, liquorice and florfenicol. The pharmaceutical composition has the function of superactive antivirus, has strong antivirus and antibiosis actions, remarkable therapeutic effect, fast effect, complete treatment and no relapse, is not easy to generate drug resistance and can be effectively used for preventing and curing the virus diseases of animals. The compound pharmaceutical composition can be powder preparation formulation. The invention also provides feed containing the compound pharmaceutical composition.
Description
Technical field
The invention belongs to field of veterinary, relate to a kind of be used to prevent and treat animal viral disease, the bonded compound medicament composition of Chinese medicine and western medicine and preparation method thereof.
Background technology
China's livestock breeding industry develops rapidly towards the direction of intensification, scale, batch production, but along with the change of feeding manner, the continuous introduction of adventive and the frequent circulation of poultry, the generation of eqpidemic disease and extensively popular and complicated day by day.Wherein, the disease that is caused by viral infection is because of new sick generation, mixed infection, virus variation, the forbidding of chemical antiviral drugs on animal etc. make disease be difficult to control more.Cause the poultry mortality as viral diseases such as the high-fever syndrome that takes place in recent years, Porcine reproductive and respiratory syndrome, porcine circovirus infection, caused enormous economic loss to aquaculture, the sound development of livestock breeding industry in serious threat.
At present, the types of drugs that is used for the treatment of animal viral disease both at home and abroad is a lot, and the bonded compound medicine of Chinese medicine, Western medicine and Chinese medicine and western medicine is arranged.Wherein, the bonded compound medicine of Chinese medicine and western medicine is because of the conditioning human body that has Chinese herbal medicine concurrently, strong, the instant effect of resistance against diseases, toxic and side effects effect little, that do not produce advantage such as drug resistance and Western medicine that improves body and advantage such as easy to use, and is more and more to its research in recent years.But Chinese herbal medicine is different with effect because of its pharmacology with Western medicine, as prescription not science, compatibility is improper also may produce some harm, does not only reach the corresponding treatment effect, also can endanger the healthy of animal.Therefore, the bonded compound medicines of Chinese medicine and western medicine has only reasonable formula, science compatibility and the strict principle of medication of holding, and could bring into play the effect of medicine to greatest extent, and the effect that obtains bringing out the best in each other.
Summary of the invention
The present invention adopts Chinese medicine and western medicine in conjunction with the control animal viral disease, and the Chinese prescription thinking is detoxifcation, and directly antiviral stops virus absorption, suppresses virus multiplication, prevents to infect normal cell again; Tonification is set upright, by improving the indirect antiviral of immunity; Blood circulation promoting and blood stasis dispelling promotes tissue repair and regeneration; Clearing away heat-damp and promoting diuresis, eliminating evil; The spleen and stomach regulating.The effect of Western medicine is antibiotic, prevents secondary infection, reduces the death that secondary infection causes.The object of the present invention is to provide a kind of compound medicament composition of efficient, quick-acting, safe control animal viral disease.Compound medicament composition reasonable recipe of the present invention, with the animal is this, from comprehensive and whole angle, improvement by virus damage and interferential physiological status, the total quality that improves vital movement, enhancing body premunition, form and be unfavorable for the internal environment of virus replication, prevent the antibacterial deterioration disease of taking advantage of a weak point simultaneously, thereby reach the purpose of prevention and treatment viral disease.
The feedstuff that another object of the present invention is to provide the preparation method of this compound medicament composition and comprise this pharmaceutical composition.
The objective of the invention is to be achieved through the following technical solutions:
The invention provides a kind of compound medicament composition of preventing and treating animal viral disease, comprise Fructus Forsythiae in the said composition, Radix Isatidis, Folium Bambusae, Radix Scutellariae, Flos Lonicerae, Folium Isatidis, the Radix Astragali, Herba Epimedii, Fructus Ligustri Lucidi, the Radix Rehmanniae, Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong, Fructus Mume, Semen Lepidii (Semen Descurainiae), Bulbus Fritillariae Cirrhosae, Pericarpium Citri Reticulatae, Radix Ophiopogonis, Radix Glycyrrhizae, florfenicol, the weight proportion of mentioned component is: Fructus Forsythiae 8-30 part, Radix Isatidis 10-50 part, Folium Bambusae 8-30 part, Radix Scutellariae 5-30 part, Flos Lonicerae 5-25 part, Folium Isatidis 10-50 part, Radix Astragali 5-30 part, Herba Epimedii 8-30 part, Fructus Ligustri Lucidi 5-30 part, Radix Rehmanniae 5-30 part, Radix Salviae Miltiorrhizae 5-20 part, Rhizoma Chuanxiong 3-20 part, Fructus Mume 3-20 part, Semen Lepidii (Semen Descurainiae) 5-30 part, Bulbus Fritillariae Cirrhosae 3-30 part, Pericarpium Citri Reticulatae 3-30 part, Radix Ophiopogonis 5-30 part, Radix Glycyrrhizae 3-30 part, florfenicol 5-50 part.
Further, the weight proportion of each composition is in this compound medicament composition: Fructus Forsythiae 10-20 part, Radix Isatidis 15-30 part, Folium Bambusae 10-30 part, Radix Scutellariae 5-20 part, Flos Lonicerae 5-20 part, Folium Isatidis 15-40 part, Radix Astragali 5-20 part, Herba Epimedii 10-20 part, Fructus Ligustri Lucidi 6-20 part, Radix Rehmanniae 6-20 part, Radix Salviae Miltiorrhizae 5-15 part, Rhizoma Chuanxiong 3-15 part, Fructus Mume 3-15 part, Semen Lepidii (Semen Descurainiae) 5-20 part, Bulbus Fritillariae Cirrhosae 3-20 part, Pericarpium Citri Reticulatae 5-20 part, Radix Ophiopogonis 10-20 part, Radix Glycyrrhizae 3-20 part, florfenicol 10-30 part.
Further, the weight proportion of various compositions is in this compound medicament composition: Fructus Forsythiae 10-15 part, Radix Isatidis 15-30 part, Folium Bambusae 10-20 part, Radix Scutellariae 5-15 part, Flos Lonicerae 5-10 part, Folium Isatidis 10-30 part, Radix Astragali 5-15 part, Herba Epimedii 10-15 part, Fructus Ligustri Lucidi 8-15 part, Radix Rehmanniae 8-15 part, Radix Salviae Miltiorrhizae 5-10 part, Rhizoma Chuanxiong 3-10 part, Fructus Mume 3-10 part, Semen Lepidii (Semen Descurainiae) 5-10 part, Bulbus Fritillariae Cirrhosae 3-10 part, Pericarpium Citri Reticulatae 5-10 part, Radix Ophiopogonis 10-15 part, Radix Glycyrrhizae 5-10 part, florfenicol 15-30 part.
Compound medicament composition of the present invention can be the other medicines dosage form, but the preferred powder of the present invention.
The present invention also provides the preparation method of the compound medicament composition of this control animal viral disease, it is characterized in that comprising the steps:
(1) taking by weighing following medicine is raw material: Fructus Forsythiae, Radix Isatidis, Folium Bambusae, Radix Scutellariae, Flos Lonicerae, Folium Isatidis, the Radix Astragali, Herba Epimedii, Fructus Ligustri Lucidi, the Radix Rehmanniae, Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong, Fructus Mume, Semen Lepidii (Semen Descurainiae), Bulbus Fritillariae Cirrhosae, Pericarpium Citri Reticulatae, Radix Ophiopogonis, Radix Glycyrrhizae, florfenicol;
(2) with each component oven dry, grinding and sieving takes by weighing the back by proportioning and mixes, and stirs, and makes powder, promptly.
The present invention also provides the feedstuff that comprises this compound medicament composition, and 1000-2000 gram compound medicament composition of the present invention is joined in 1000 kilograms of feedstuffs, can treat or prevent the viral disease of poultry.
The present invention has following advantage:
1) the present invention is the Chinese medicine and western medicine compound preparation, is this with the animal, from integral body, treating both the principal and secondary aspects of a disease;
2) pharmaceutical composition reasonable recipe of the present invention, science;
3) pharmaceutical composition antiviral antibacterial action of the present invention is strong, evident in efficacy, and effect rapidly, is not thoroughly recurred, and is difficult for producing drug resistance.
, it should be understood that described embodiment only is for the present invention is described, rather than limit the scope of the invention by any way more specific description the present invention by the following example.
The specific embodiment
Embodiment 1
8 parts of Fructus Forsythiaes, 10 parts of Radix Isatidis, 8 parts on Folium Bambusae, 5 parts of Radix Scutellariaes, 5 parts of Flos Loniceraes, 10 parts of Folium Isatidiss, 5 parts of the Radixs Astragali, 8 parts of Herba Epimedii, 5 parts of Fructus Ligustri Lucidi, 5 parts in the Radix Rehmanniae, 5 parts of Radix Salviae Miltiorrhizaes, 3 parts of Rhizoma Chuanxiongs, 3 parts of Fructus Mumes, 5 parts of Semen Lepidii (Semen Descurainiae)s, 3 parts of Bulbus Fritillariae Cirrhosae, 3 parts of Pericarpium Citri Reticulataes, 5 parts of Radix Ophiopogonis, 3 parts in Radix Glycyrrhizae, 5 parts of florfenicols, oven dry, pulverize, sieve, mix by said ratio, stir, make powder, promptly.
Embodiment 2
30 parts of Fructus Forsythiaes, 50 parts of Radix Isatidis, 30 parts on Folium Bambusae, 30 parts of Radix Scutellariaes, 25 parts of Flos Loniceraes, 50 parts of Folium Isatidiss, 30 parts of the Radixs Astragali, 30 parts of Herba Epimedii, 30 parts of Fructus Ligustri Lucidi, 30 parts in the Radix Rehmanniae, 20 parts of Radix Salviae Miltiorrhizaes, 20 parts of Rhizoma Chuanxiongs, 20 parts of Fructus Mumes, 30 parts of Semen Lepidii (Semen Descurainiae)s, 30 parts of Bulbus Fritillariae Cirrhosae, 30 parts of Pericarpium Citri Reticulataes, 30 parts of Radix Ophiopogonis, 30 parts in Radix Glycyrrhizae, 50 parts of florfenicols, oven dry, pulverize, sieve, mix by said ratio, stir, make powder, promptly.
Embodiment 3
10 parts of Fructus Forsythiaes, 15 parts of Radix Isatidis, 10 parts on Folium Bambusae, 5 parts of Radix Scutellariaes, 5 parts of Flos Loniceraes, 15 parts of Folium Isatidiss, 5 parts of the Radixs Astragali, 10 parts of Herba Epimedii, 6 parts of Fructus Ligustri Lucidi, 6 parts in the Radix Rehmanniae, 5 parts of Radix Salviae Miltiorrhizaes, 3 parts of Rhizoma Chuanxiongs, 3 parts of Fructus Mumes, 5 parts of Semen Lepidii (Semen Descurainiae)s, 3 parts of Bulbus Fritillariae Cirrhosae, 5 parts of Pericarpium Citri Reticulataes, 10 parts of Radix Ophiopogonis, 3 parts in Radix Glycyrrhizae, 10 parts of florfenicols, oven dry, pulverize, sieve, mix by said ratio, stir, make powder, promptly.
Embodiment 4
20 parts of Fructus Forsythiaes, 30 parts of Radix Isatidis, 30 parts on Folium Bambusae, 20 parts of Radix Scutellariaes, 20 parts of Flos Loniceraes, 40 parts of Folium Isatidiss, 20 parts of the Radixs Astragali, 20 parts of Herba Epimedii, 20 parts of Fructus Ligustri Lucidi, 20 parts in the Radix Rehmanniae, 15 parts of Radix Salviae Miltiorrhizaes, 15 parts of Rhizoma Chuanxiongs, 15 parts of Fructus Mumes, 20 parts of Semen Lepidii (Semen Descurainiae)s, 20 parts of Bulbus Fritillariae Cirrhosae, 20 parts of Pericarpium Citri Reticulataes, 20 parts of Radix Ophiopogonis, 20 parts in Radix Glycyrrhizae, 30 parts of florfenicols, oven dry, pulverize, sieve, mix by said ratio, stir, make powder, promptly.
Embodiment 5
10 parts of Fructus Forsythiaes, 15 parts of Radix Isatidis, 10 parts on Folium Bambusae, 5 parts of Radix Scutellariaes, 5 parts of Flos Loniceraes, 10 parts of Folium Isatidiss, 5 parts of the Radixs Astragali, 10 parts of Herba Epimedii, 8 parts of Fructus Ligustri Lucidi, 8 parts in the Radix Rehmanniae, 5 parts of Radix Salviae Miltiorrhizaes, 3 parts of Rhizoma Chuanxiongs, 3 parts of Fructus Mumes, 5 parts of Semen Lepidii (Semen Descurainiae)s, 3 parts of Bulbus Fritillariae Cirrhosae, 5 parts of Pericarpium Citri Reticulataes, 10 parts of Radix Ophiopogonis, 5 parts in Radix Glycyrrhizae, 15 parts of florfenicols, oven dry, pulverize, sieve, mix by said ratio, stir, make powder, promptly.
Embodiment 6
15 parts of Fructus Forsythiaes, 30 parts of Radix Isatidis, 20 parts on Folium Bambusae, 15 parts of Radix Scutellariaes, 10 parts of Flos Loniceraes, 30 parts of Folium Isatidiss, 15 parts of the Radixs Astragali, 15 parts of Herba Epimedii, 15 parts of Fructus Ligustri Lucidi, 15 parts in the Radix Rehmanniae, 10 parts of Radix Salviae Miltiorrhizaes, 10 parts of Rhizoma Chuanxiongs, 10 parts of Fructus Mumes, 10 parts of Semen Lepidii (Semen Descurainiae)s, 10 parts of Bulbus Fritillariae Cirrhosae, 10 parts of Pericarpium Citri Reticulataes, 15 parts of Radix Ophiopogonis, 10 parts in Radix Glycyrrhizae, 30 parts of florfenicols, oven dry, pulverize, sieve, mix by said ratio, stir, make powder, promptly.
Embodiment 7
This traditional Chinese compound medicine compositions is prepared as follows and obtains:
1) takes by weighing following raw materials according: 12 parts of Fructus Forsythiaes, 12 parts of Radix Isatidis, 15 parts on Folium Bambusae, 10 parts of Radix Scutellariaes, 8 parts of Flos Loniceraes, 20 parts of Folium Isatidiss, 10 parts of the Radixs Astragali, 12 parts of Herba Epimedii, 10 parts of Fructus Ligustri Lucidi, 10 parts in the Radix Rehmanniae, 8 parts of Radix Salviae Miltiorrhizaes, 8 parts of Rhizoma Chuanxiongs, 8 parts of Fructus Mumes, 8 parts of Semen Lepidii (Semen Descurainiae)s, 8 parts of Bulbus Fritillariae Cirrhosae, 8 parts of Pericarpium Citri Reticulataes, 12 parts of Radix Ophiopogonis, 8 parts in Radix Glycyrrhizae, 20 parts of florfenicols;
2) with each component oven dry, sieve after crushed, take by weighing the back by proportioning and mix, stir, make powder, promptly.
Observing 1 pair of pig wean of example back multisystemic exhaustion syndrome therapeutic effect observes
Certain pig farm, area, Jiujiang, Jiangxi Province, lassitude appears in wean back piglet group, the phenomenon of being off one's feed, only heating of pig, dyspnea, cough, sneeze, palor, jaundice, diarrhoea, poor growth, body surface lymph node, particularly inguinal lymph nodes enlargement.Infect the pig wean back multisystemic exhaustion syndrome that causes for pig circular ring virus II type after diagnosing.
Adopt the compound medicament composition of the embodiment of the invention 1 to treat.Above-mentioned sick pig is divided into 2 groups at random, every group 120, the 1st group of compound medicament composition treatment that gives embodiment 1 adopts the drinking-water medication to give the compound medicament composition of embodiment 1, get compound medicament composition 200 grams that 10 kilograms of 80 ℃ of hot water add embodiment 1, soak twice, each 45 minutes, merge medicinal liquid twice, thin up to 100 kilogram, medicinal liquid is drunk for pig, and the medicinal residues spice is fed, continuous use 7 days; The 2nd group is the blank group, does not add any medicine in the feedstuff.Result of the test sees Table 1.
Table 1 treatment pig wean back multisystemic exhaustion syndrome result of the test
| Group | Size of animal | Cure a number | Cure rate | A dead number | Mortality rate |
| The 1st group | 120 | 97 | 80.8％ | 8 | 6.7％ |
| The 2nd group | 120 | 16 | 13.3％ | 36 | 30％ |
Result of the test shows that the compound medicament composition of embodiment 1 has excellent curative to pig wean back multisystemic exhaustion syndrome, and significantly better than the blank group, difference is (P＜0.01) extremely significantly.
Observe the preventive effect observation that 2 couples of pig circular ring virus II of example type infects
Select Beijing to have the large-scale pig farm of pig circular ring virus II type infection morbidity history to carry out prophylactic tria, evaluation effect.
Piglet after 2000 wean on this pig farm is divided into two groups at random, and wherein one group is the medicine group, by the compound medicament composition that adds 1 kilogram of embodiment 2 in the feedstuff per ton, and logotype 7 days, another group is not added any medicine for the blank group in the feedstuff.Experimental observation 30 days, result of the test sees Table 2.
The result of the test that table 2 prevention pig circular ring virus II type infects
| Group | Size of animal | A morbidity number | Sickness rate |
| The medicine group | 1000 | 20 | 2％ |
| The blank group | 1000 | 276 | 27.6％ |
Result of the test shows that the compound medicament composition prevention pig circular ring virus II type of embodiment 2 infects effective percentage and reaches 98%, has the effect that good preventing pig circular ring virus II type infects, and compares significant difference (P＜0.05) with the blank group.
Observing 3 pairs of high fever syndrome of pigs therapeutic effect of example observes
Pig farm, Sichuan Province sow and market pig sudden onset, body temperature 41-42 ℃, appetite descends, and drinking-water reduces, and the pig lethargy that has did not rise in 4-7 days, and the urine jaundice is suffered from diarrhoea after the first constipation, nervous symptoms is arranged before dead.Cuing open inspection as seen has tangible deteriorated blood symptom, pulmonary interstitial edema, and liver becomes, and gastric mucosa has ulcer, and the kidney enlargement has the petechia, hydrothorax.Tentative diagnosis is a high fever syndrome of pigs.
200 sows and 3000 market pigs to morbidity are treated, be divided into sow group and market pig group, adopt the drinking-water medication to give the compound medicament composition of embodiment 3, get compound medicament composition 200 grams that 10 kilograms of 80 ℃ of hot water add embodiment 3, soak twice, each 45 minutes, merge medicinal liquid twice, thin up to 100 kilogram, medicinal liquid is drunk for pig, and the medicinal residues spice is fed; Treatment is 7 days continuously.The 8th day viewing test result, result of the test sees Table 3.
Table 3 treatment high fever syndrome of pigs result of the test
| Group | Size of animal | Cure a number | Cure rate |
| The sow group | 200 | 172 | 86.0％ |
| The market pig group | 3000 | 2644 | 88.1％ |
Result of the test shows that the compound medicament composition of embodiment 3 has notable therapeutic effect to high fever syndrome of pigs.
Observing the preventive effect of 4 pairs of high fever syndrome of pigs of example observes
Select Beijing to have the large-scale pig farm of high fever syndrome of pigs morbidity history to carry out prophylactic tria, evaluation effect.
The 500 head growth growing and fattening pigs on this pig farm are divided into two groups at random, wherein one group is the pharmaceutical feed group, prevent and treat the feedstuff of animal viral disease, added the compound medicament composition of embodiment 5 in this feedstuff, addition is that feedstuff per ton adds 1 kilogram of compound medicament composition, adopt the pulsed medication, medication every month 7 days was used 3 months continuously; Another group only gives normal diet for the blank group, does not add any medicine in the feedstuff.Result of the test sees Table 4.
Table 4 pig high fever syndrome prevention result of the test
| Group | Size of animal | A morbidity animal number | Sickness rate (%) | Dead animal head number | Mortality rate (%) |
| The pharmaceutical feed group | 250 | 21 | 8.4 | 10 | 4 |
| The blank group | 250 | 120 | 48 | 65 | 26 |
Result of the test shows that the M ﹠ M of medicine group significantly is lower than blank group (P＜0.05), and the prevention effective percentage reaches 91.6%, and the compound medicament composition of embodiment 5 has significant preventive effect to high fever syndrome of pigs.
Observe example 5
Use the compound medicament composition control pig circular ring virus II type of embodiment 6 to infect on 16785 pigs in 16 pig farms, Sichuan Province, the prevention effective percentage reaches more than 90.8%, and the treatment effective percentage reaches more than 85.5%.Result of the test shows that the compound medicament composition of embodiment 6 can effectively be prevented and treated pig circular ring virus II type and infect.
Claims (6)
1. compound medicament composition of preventing and treating the domestic animal viral disease, it is characterized in that by Fructus Forsythiae, Radix Isatidis, Folium Bambusae, Radix Scutellariae, Flos Lonicerae, Folium Isatidis, the Radix Astragali, Herba Epimedii, Fructus Ligustri Lucidi, the Radix Rehmanniae, Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong, Fructus Mume, Semen Lepidii (Semen Descurainiae), Bulbus Fritillariae Cirrhosae, Pericarpium Citri Reticulatae, Radix Ophiopogonis, Radix Glycyrrhizae, florfenicol is formed, and the weight proportion of mentioned component is: Fructus Forsythiae 8-30 part, Radix Isatidis 10-50 part, Folium Bambusae 8-30 part, Radix Scutellariae 5-30 part, Flos Lonicerae 5-25 part, Folium Isatidis 10-50 part, Radix Astragali 5-30 part, Herba Epimedii 8-30 part, Fructus Ligustri Lucidi 5-30 part, Radix Rehmanniae 5-30 part, Radix Salviae Miltiorrhizae 5-20 part, Rhizoma Chuanxiong 3-20 part, Fructus Mume 3-20 part, Semen Lepidii (Semen Descurainiae) 5-30 part, Bulbus Fritillariae Cirrhosae 3-30 part, Pericarpium Citri Reticulatae 3-30 part, Radix Ophiopogonis 5-30 part, Radix Glycyrrhizae 3-30 part, florfenicol 5-50 part.
2. the compound medicament composition of the described control of claim 1 domestic animal viral disease is characterized in that the weight proportion of mentioned component is: Fructus Forsythiae 10-20 part, Radix Isatidis 15-30 part, Folium Bambusae 10-30 part, Radix Scutellariae 5-20 part, Flos Lonicerae 5-20 part, Folium Isatidis 15-40 part, Radix Astragali 5-20 part, Herba Epimedii 10-20 part, Fructus Ligustri Lucidi 6-20 part, Radix Rehmanniae 6-20 part, Radix Salviae Miltiorrhizae 5-15 part, Rhizoma Chuanxiong 3-15 part, Fructus Mume 3-15 part, Semen Lepidii (Semen Descurainiae) 5-20 part, Bulbus Fritillariae Cirrhosae 3-20 part, Pericarpium Citri Reticulatae 5-20 part, Radix Ophiopogonis 10-20 part, Radix Glycyrrhizae 3-20 part, florfenicol 10-30 part.
3. the compound medicament composition of the described control of claim 1 domestic animal viral disease is characterized in that weight proportion is: Fructus Forsythiae 10-15 part, Radix Isatidis 15-30 part, Folium Bambusae 10-20 part, Radix Scutellariae 5-15 part, Flos Lonicerae 5-10 part, Folium Isatidis 10-30 part, Radix Astragali 5-15 part, Herba Epimedii 10-15 part, Fructus Ligustri Lucidi 8-15 part, Radix Rehmanniae 8-15 part, Radix Salviae Miltiorrhizae 5-10 part, Rhizoma Chuanxiong 3-10 part, Fructus Mume 3-10 part, Semen Lepidii (Semen Descurainiae) 5-10 part, Bulbus Fritillariae Cirrhosae 3-10 part, Pericarpium Citri Reticulatae 5-10 part, Radix Ophiopogonis 10-15 part, Radix Glycyrrhizae 5-10 part, florfenicol 15-30 part.
4. the compound medicament composition of each described control domestic animal viral disease of claim 1-3 is characterized in that it is a kind of powder.
5. the preparation method as the compound medicament composition of each described control domestic animal viral disease of claim 1-4 is characterized in that comprising the steps:
(1) taking by weighing following medicine is raw material: Fructus Forsythiae, Radix Isatidis, Folium Bambusae, Radix Scutellariae, Flos Lonicerae, Folium Isatidis, the Radix Astragali, Herba Epimedii, Fructus Ligustri Lucidi, the Radix Rehmanniae, Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong, Fructus Mume, Semen Lepidii (Semen Descurainiae), Bulbus Fritillariae Cirrhosae, Pericarpium Citri Reticulatae, Radix Ophiopogonis, Radix Glycyrrhizae, florfenicol;
(2) with each component oven dry, grinding and sieving takes by weighing the back by proportioning and mixes, and stirs, and makes powder, promptly.
6. a feedstuff of preventing and treating the domestic animal viral disease is characterized in that containing in this feedstuff each described compound medicament composition of claim 1-4, and its content is the compound medicament composition that comprises the 1000-2000 gram in per 1000 kilograms of feedstuffs.
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