CN106361902A - Traditional Chinese medicine composition for preventing and treating livestock diarrhea and preparation method thereof - Google Patents
Traditional Chinese medicine composition for preventing and treating livestock diarrhea and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/85—Verbenaceae (Verbena family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/59—Menispermaceae (Moonseed family), e.g. hyperbaena or coralbead
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
Abstract
The invention provides a traditional Chinese medicine composition for preventing and treating livestock diarrhea. The traditional Chinese medicine composition is characterized by being prepared from the following medicine raw materials of Chinese pulsatilla roots, radix sophorae flavescentis, rhizoma coptidis, arrowshaped tinospora roots, atractylodes rhizomes, Chinese fevervine herbs, negundo chastetree fruits and paniculate microcos leaves. By the adoption of the traditional Chinese medicine compound preparation, in the process of large-scale pig raising, the diarrhea rate of suckling pigs can be lowered, the feed intake can be increased, the appetite can be enhanced, and the traditional Chinese medicine composition can be applied and popularized in large-scale pig farms.
Description
Technical field
The invention belongs to Chinese medicine compound field, it is related to a kind of Chinese medicine composition of preventing and treating diarrhea in livestock and preparation method thereof.
Background technology
Piglet diarrhea is one kind typically multifactor property disease under intensive pig production working condition, is current most serious
One of piglet diseases group, is also the major reason causing piglet dead, ranks first in pig industry harm.Piglet diarrhoea is often led
Cause that price of deed rate is relatively low, piglet survival ratio declines, poor growth, growth promoter are stagnated, or even death.Piglet diarrhea is caused to send out
The raw cause of disease is complicated, often shows as the result of many factors interaction, in intersecting mixed infection, leads to clinical diagnosises and preventing and treating
Difficult.Most of plants are all prevented by interpolation antibiotic in feedstuff or drinking-water or other chemicalses or treat
Piglet diarrhoea.But because choice of drug is improper, typically difficulty has positive effect, have even can due to antibiotic usage excessive and
Diarrhoea aggravation occurs.On the other hand, with the life-time service of these medicines, various problems have also highlighted out, as drug resistance
Produce etc..
Faced with this situation, most of plant uses chemical medicine or antibiotic, but this method easily leads to pigletss to be exempted from
Epidemic disease power declines, and the impact later stage fattens.Treatment by Chinese herbs disease focuses on treating both the principal and secondary aspects of a disease, has regulation and improve body while antibacterial
The characteristic of state, and green Chinese is natural, using safety, drug residue free.Therefore find a kind of highly effective and safe, improve immunity
The Chinese medicine compound that power, prevention pigletss are suffered from diarrhoea is extremely crucial.
Content of the invention
It is an object of the invention to provide a kind of highly effective and safe, improve feed intake, preventing and treating diarrhea in livestock Chinese medicine composition and
Its preparation method.
To achieve these goals, the technical solution adopted in the present invention is as follows:
A kind of preventing and treating diarrhea in livestock Chinese medicine composition it is characterised in that this Chinese medicine composition by following parts by weight crude drug
Be prepared from: 20-30 part Herba Paederiae, 20-30 part Radix Pulsatillae, 10-20 part Radix Sophorae Flavescentiss, 10-20 part Rhizoma Coptidis, 10-20 part Radix Tinosporae,
10-20 part Rhizoma Atractylodis, 10-20 part Fructus Viticis Negundo, 10-20 part Folium Microcoris paniculatae.
Further, the Chinese medicine composition of described preventing and treating diarrhea in livestock is it is characterised in that it is by following weight proportioning
Crude drug is prepared from: 22-28 part Herba Paederiae, 22-28 part Radix Pulsatillae, 12-18 part Radix Sophorae Flavescentiss, 12-18 part Rhizoma Coptidis, 12-18 part
Radix Tinosporae, 12-18 part Rhizoma Atractylodis, 2-18 part Fructus Viticis Negundo, 12-18 part Folium Microcoris paniculatae.
Further, the Chinese medicine composition of described preventing and treating diarrhea in livestock is it is characterised in that it is by following weight proportioning
Crude drug be prepared from: 24-26 part Herba Paederiae, 24-26 part Radix Pulsatillae, 14-16 part Radix Sophorae Flavescentiss, 14-16 part Rhizoma Coptidis, 14-16
Part Radix Tinosporae, 14-16 Rhizoma Atractylodis, 14-16 part Fructus Viticis Negundo, 14-16 part Folium Microcoris paniculatae.
Further, described preventing and treating diarrhea in livestock Chinese medicine composition it is characterised in that: described Chinese medicine composition is scattered
Agent, capsule, oral liquid, granule, pill or tablet.
Present invention also offers the preparation method of the Chinese medicine composition of described preventing and treating diarrhea in livestock is it is characterised in that step
As follows:
1) Herba Paederiae, the Radix Pulsatillae, Radix Sophorae Flavescentiss, Rhizoma Coptidis, Radix Tinosporae, Fructus Viticis Negundo and the Folium Microcoris paniculatae of recipe quantity are weighed, add weight is 8-15
The alcohol reflux of times amount water or 40%-70% 2-3 time, each 1-2 hour, united extraction liquid, filters, is evaporated to relatively
1.20 ~ 1.28(50 DEG C of density), drying under reduced pressure become dry cream；
2) dry cream and Rhizoma Atractylodis are respectively crushed into fine powder, cross 100 mesh sieves, add appropriate amount of auxiliary materials, mix, prepare capsule, granule
Agent or tablet.
Further, in step 1), weigh the Herba Paederiae of recipe quantity, the Radix Pulsatillae, Radix Sophorae Flavescentiss, Rhizoma Coptidis, Radix Tinosporae, Fructus Viticis Negundo and
Folium Microcoris paniculatae, the alcohol reflux for 10-12 times amount water or 50%-60% for the add weight 2 times, each 1-2 hour.
Medicine composition and analysis:
The Radix Pulsatillae: cold in nature；Return stomach, large intestine channel；Radix Pulsatillae medical value is high, finds out there is description from above-mentioned history tree monograph more.
The traditional Chinese medical science thinks, the Radix Pulsatillae has heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery, improving eyesight, effect of removing dampness and killing parasites；Cure mainly pyretic toxicity dysentery, epistaxis, blood
Hemorrhoid, leukorrhagia, pudendal pruritus, ulcerative carbuncle, the disease such as scrofula.
Radix Sophorae Flavescentiss: heat clearing and damp drying, parasite killing, diuresis.For hematodiarrhoea, have blood in stool, jaundice urine retention, leucorrhea with red and white discharge, swelling of the vulva pudendal pruritus, wet
Rash, eczema, skin pruritus, scabies leprosy, external treatment trichomonal vaginitis.
Rhizoma Coptidis: Rhizoma Coptidis have a very strong antibacterial action, suppression staphylococcus aureuses, Hemolytic streptococcuss, streptococcus pneumoniae,
Meningococcus, dysentery bacterium, anthrax bacillus etc..Also there is antiviral, protozoacide acts on.In addition Rhizoma Coptidis also have Detoxication,
As resisted bacteriotoxin, reduce staphylococcus aureus coagulase, hemolysin potency, reduce colibacillary virulence etc..And
Antiinflammatory, antipyretic effect.
Radix Tinosporae: the dried root of menispermaceous plantss limacia sagittata or Radix Tinosporae.Bitter in the mouth, cold in nature.Return lung, large intestine channel.Effect:
Heat-clearing and toxic substances removing, sore-throat relieving, pain relieving.For laryngopharynx swelling and pain, carbuncle furunculosis, have loose bowels, dysentery, epigastric pain." book on Chinese herbal medicine is new again ": YIN nourishing fall
Fire, slakes thirst and help produce saliva." property of medicine is examined ": removing toxic substances.Throat numbness is anxious, and erosion of mucous membrane of the oral cavity preferably takes.Cellulitis carbuncle carbuncle on the back, snakes and scorpions insect bite, mill applies.Control ophthalmalgia, ear
Swollen, cough due to heat, haze miasma, tell nosebleed, all outer diseases.
Rhizoma Atractylodis: acrid in the mouth, hardship, warm in nature.Returns spleen, stomach, Liver Channel.Drying damp and strengthening spleen, expelling wind and cold, improving eyesight.For retention of dampness in middle-JIAO, gastral cavity
Distention and fullness in the abdomen, has loose bowels, edema, and tinea pedis flaccidity is knitted, rheumatic arthralgia, anemofrigid cold, and eyes dusk is puckery.Rhizome contains volatile oil about 5～9%, mainly
Composition is atractylol, hinesol, sagittol etc..Rhizoma Atractylodis can suppress multiple enteropahtogenic microganism growths, to escherichia coli, intestinal
The pathogen such as scorching Salmonella, staphylococcus aureuses, Pseudomonas aeruginosa have significantly suppression and deactivation.
Folium Microcoris paniculatae, the dried leaves of Tiliaceae plant Microcos paniculata.Sour in the mouth, cool in nature.Returns spleen, stomach.Effect: relieving dyspepsia, clearly
Diarrhea of heat type is wet.For eating accumulation, cold, fever, jaundice due to damp-heat etc..
Fructus Viticis Negundo: for the fruit of Verbenaceae five-leaved chaste tree.Acrid in the mouth is bitter, warm in nature.Indication: wind-dispelling, expectorant, circulation of qi promoting,
Pain relieving.Cure cold, cough, asthma, migratory arthralgia, malaria, stomachache, hernia, anal fistula." Yuhuan will ": removing stagnancy of indigested food and making QI downward." Guangzhou plant
Will ": wind-dispelling, clearing away phlegm, antitussive." Nanning City's medicine will ": " warming the meridian dissipating blood stasis, expelling pathogenic factors from muscles by diaphoresis.Cure cold, malaria, asthma." " Sichuan
Chinese medicinal herbal ": nourishing the liver removes wind, promoting the circulation of QI to relieve pain.The hiccup due to cold that cures the wound is inverse, cough with asthma, dyspepsia, and inguinal hernia and anal fistula life are managed.
Herba Paederiae, acrid in the mouth, hardship, warm in nature.Return liver, spleen channel.Indication: circulation of qi promoting removing blood stasis；Xiao Ji Zhi Tong.Main vim and vigour are pained；
Eating accumulation；Abdominal distention；Amenorrhea due to stagnation of blood；Dysmenorrhea；Lump in the abdomen tumor mass in the abdomen；Traumatic injury.Pharmacological action: 1. antitumor action: chicken
Dung rattan plays the role of directly to kill oncocyte；2 antibacterial actions: Herba Paederiae volatile oil test tube interior energy suppression staphylococcus aureuses, β-
The growth of Hemolytic streptococcuss, escherichia coli, Bacillus typhi, vibrio cholera etc.；The effect of 3 leukocyte increasings；4 antiinflammatory actions
Deng.
The invention has the beneficial effects as follows:
The invention provides a kind of pharmaceutical composition of preventing and treating piglet diarrhea, and it is theoretical, in heat clearing away to provide Traditional Chinese Medicine veterinary
Prepare under removing dampness antidiarrheal, the prescription foundation of strengthening the spleen to promote digestion and control principle, it not only has good clearing away heat and eliminating dampness and stops
Rush down, strengthening the spleen to promote digestion the effects such as, but also have that clinical efficacy is obvious, side effect is low, noresidue, be not likely to produce drug resistance, cost
The features such as cheap, easy to use, for piglet diarrhea, there is good prevention and treatment effect.Using this kind of compound Chinese medicinal preparation
Pigletss diarrhea rate can be reduced during large scale of pig farm, improve feed intake, appetite strengthening, can push away in large scale of pig farm factory
Wide application.The dysentery relieving of its medicine, effect of antidiarrheal is extremely notable, and is safe to animal subject, reliably.
Specific embodiment
Based on the embodiment in the present invention, those of ordinary skill in the art are obtained under the premise of not making creative work
The every other embodiment obtaining, broadly falls into the scope of protection of the invention.
Embodiment 1
A kind of Herbal compound capsule agent improving feed intake, reducing diarrhea rate, comprising: 25 parts of Radix Pulsatillaes, 15 parts of Radix Sophorae Flavescentiss, 15 parts of Huangs
Even, 15 parts of Radix Tinosporaes, 15 parts of Rhizoma Atractylodis, 25 parts of Herba Paederiaes, 15 parts of Fructus Viticis Negundo, 15 parts of Folium Microcoris paniculataes.Its concrete preparation method is as follows:
1) Herba Paederiae, the Radix Pulsatillae, Radix Sophorae Flavescentiss, Rhizoma Coptidis, Radix Tinosporae, Fructus Viticis Negundo and the Folium Microcoris paniculatae of recipe quantity are weighed, add weight is 12 times
Amount decocting boils 3 times, 1 hour every time, and united extraction liquid filters, is evaporated to relative density 1.25(50 DEG C), drying under reduced pressure becomes
Dry cream；
2) dry cream and Rhizoma Atractylodis are respectively crushed into fine powder, cross 100 mesh sieves, add appropriate amount of auxiliary materials, mix, prepare granule, be dried, fill
Dress, obtains final product capsule.
Embodiment 2
A kind of Herbal compound capsule agent, granule or tablet improving feed intake, reducing diarrhea rate, comprising: 20 portions of Radix Pulsatillaes, 10
Part Radix Sophorae Flavescentiss, 10 parts of Rhizoma Coptidis, 10 parts of Radix Tinosporaes, 10 parts of Rhizoma Atractylodis, 20 parts of Herba Paederiaes, 10 parts of Fructus Viticis Negundo, 10 parts of Folium Microcoris paniculataes.
Its concrete preparation method is as follows:
Weigh Herba Paederiae, the Radix Pulsatillae, Radix Sophorae Flavescentiss, Rhizoma Coptidis, Rhizoma Atractylodis, Radix Tinosporae, Fructus Viticis Negundo and the Folium Microcoris paniculatae of recipe quantity, add weight is 10
The alcohol reflux of times amount 60% 2 times, 1 hour every time, united extraction liquid, filters, is evaporated to relative density 1.20(50
DEG C), drying under reduced pressure become dry cream, pulverize, cross 100 mesh sieves, add appropriate amount of auxiliary materials, plus appropriate amount of ethanol makes granule, prepare capsule,
Granule or tablet.
Embodiment 3
A kind of Chinese medicine compound powder improving feed intake, reducing diarrhea rate: weigh each crude drug, 30 parts of hoary hairs by following weight
Father-in-law, 20 parts of Radix Sophorae Flavescentiss, 20 parts of Rhizoma Coptidis, 20 parts of Radix Tinosporaes, 20 parts of Rhizoma Atractylodis, 30 parts of Herba Paederiaes, 20 parts of Fructus Viticis Negundo, 20 parts of Folium Microcoris paniculataes.Will
After above-mentioned each crude drug is pulverized, cross 80 mesh sieves, subpackage, obtain final product.
Illustrate that the present invention prevents the beneficial effect of the Chinese medicine compound of pigletss diarrhoea below by way of concrete test example.
Test example 1
1 materials and methods
1.1 trial drug
Test drug: by happy people's peace (Beijing) development in science and technology company limited provide.
Comparison medicine: ciprofloxacin injection.
1.2 experimental animal
The Landrace of 1.3 kilograms about of 5 age in days providing for Beijing herding company and the bi-crossbreeding of Large White.Totally 120
Head pig, is randomly divided into three groups, every group 40, is treated using preparation embodiment 1 and embodiment 2 and control drug respectively.System
Standby embodiment 1 or 2 medicines, in 1g medicine, addition 10ml is boiled puts in warm water, after stirring evenly, gavages, daily 2 times, is used in conjunction 2
My god.Matched group is ciprofloxacin injection, 5mg, intramuscular injection, and one time a day, is used in conjunction 2 days.
Efficacy determination:
Recovery from illness: through treatment, ill piglet spirit is normal, sucks the breast or food is normal, formed stools, neither too hard, nor too soft, color and abnormal smells from the patient
Normally, clinical symptoms are wholly absent, and recover normal.
Effective: through treatment, the ill piglet mental status takes a turn for the better, and appetite strengthens, and fecal character takes a turn for the better, wherein moisture substantially subtracts
Few, clinical symptom remission.
Invalid: through treatment, ill piglet spirit, appetite no take a turn for the better, fecal character no takes a turn for the better, aggravation or use other instead
Drug therapy, in addition dead.
1.3 experimental results:
1.3.1 pigletss production performance changes
Every repetition average weight gain is counted according to the situation of weighing that each repeats pig, the results are shown in Table 1.
Table 1 early stage pigletss production performance/head, kg
| Group | Starting weight | End weight | Daily gain (adg) |
| Treatment group 1 | 1.36±0.05 | 8.48±0.03 | 0.28 |
| Treatment group 2 | 1.40±0.01 | 8.84±0.02 | 0.30 |
| Matched group | 1.38±0.02 | 7.89±0.01 | 0.26 |
As can be seen from Table 1, the 2 groups of daily gains for the treatment of group 1 and treatment group adding Chinese medicine compound are higher than matched group, thus may be used
See, the Chinese medicine compound adding the present invention can improve the feed intake of pigletss.
The degree 1.3.1 pigletss are suffered from diarrhoea
The total effective rate of embodiment 1 medicine and experimental example 2 medicine is respectively 97.5% and 100.0%, and matched group is 83.3%, test
Group is compared with matched group, and test group is higher than matched group.The cure rate of embodiment 1 medicine and embodiment 2 medicine is respectively 92.5% He
92.5%, matched group is 73.3%, and test group is compared with matched group, and cure rate is significantly raised, illustrates that this medicine has relatively to diarrhea of pigs
Good therapeutical effect, it is to the therapeutical effect of piglet diarrhea the results detailed in Table 2.
The diarrhoea degree therapeutic outcome of table 2 pigletss
| Group | Number of cases | Recovery from illness | Effectively | Invalid | Effective percentage % |
| Treatment group 1 | 40 | 37 | 2 | 1 | 97.50% |
| Treatment group 2 | 40 | 37 | 3 | 0 | 100.0% |
| Matched group | 30 | 22 | 3 | 5 | 83.33% |
1.4 conclusions:
Prevention pigletss diarrhoea is the difficult point of aquaculture, and the result of this test shows, adds Chinese medicine compound and can improve feed intake, significantly
Reduce diarrhea rate, the dysentery relieving of its medicine, effect of antidiarrheal is extremely notable, and is safe to animal subject, reliably.
Claims (7)
1. a kind of preventing and treating diarrhea in livestock Chinese medicine composition it is characterised in that this Chinese medicine composition by following parts by weight raw material
Medicine is prepared from: 20-30 part Herba Paederiae, 20-30 part Radix Pulsatillae, 10-20 part Radix Sophorae Flavescentiss, 10-20 part Rhizoma Coptidis, 10-20 part gold fruit
Olive, 10-20 part Rhizoma Atractylodis, 10-20 part Fructus Viticis Negundo, 10-20 part Folium Microcoris paniculatae.
2. the Chinese medicine composition of preventing and treating diarrhea in livestock according to claim 1 is it is characterised in that it is by following weight proportioning
Crude drug be prepared from: 22-28 part Herba Paederiae, 22-28 part Radix Pulsatillae, 12-18 part Radix Sophorae Flavescentiss, 12-18 part Rhizoma Coptidis, 12-18
Part Radix Tinosporae, 12-18 part Rhizoma Atractylodis, 2-18 part Fructus Viticis Negundo, 12-18 part Folium Microcoris paniculatae.
3. the Chinese medicine composition of preventing and treating diarrhea in livestock according to claim 1 is it is characterised in that it is by following weight proportioning
Crude drug be prepared from: 24-26 part Herba Paederiae, 24-26 part Radix Pulsatillae, 14-16 part Radix Sophorae Flavescentiss, 14-16 part Rhizoma Coptidis, 14-16
Part Radix Tinosporae, 14-16 Rhizoma Atractylodis, 14-16 part Fructus Viticis Negundo, 14-16 part Folium Microcoris paniculatae.
4. the Chinese medicine composition according to the arbitrary described preventing and treating diarrhea in livestock of claim 1-3 it is characterised in that: described Chinese medicine group
Compound is powder, capsule, oral liquid, granule, pill or tablet.
5. a kind of preparation method of the Chinese medicine composition of preventing and treating diarrhea in livestock as claimed in claim 4 is it is characterised in that step
As follows:
1) Herba Paederiae, the Radix Pulsatillae, Radix Sophorae Flavescentiss, Rhizoma Coptidis, Radix Tinosporae, Fructus Viticis Negundo and the Folium Microcoris paniculatae of recipe quantity are weighed, add weight is 8-15
The alcohol reflux of times amount water or 40%-70% 2-3 time, each 1-2 hour, united extraction liquid, filters, is evaporated to relatively
1.20 ~ 1.28(50 DEG C of density), drying under reduced pressure become dry cream；
2) dry cream and Rhizoma Atractylodis are respectively crushed into fine powder, cross 100 mesh sieves, add appropriate amount of auxiliary materials, mix, prepare capsule, granule
Agent or tablet.
6. according to claim 5 preventing and treating diarrhea in livestock Chinese medicine composition preparation method it is characterised in that: step 1)
In, weigh Herba Paederiae, the Radix Pulsatillae, Radix Sophorae Flavescentiss, Rhizoma Coptidis, Radix Tinosporae, Fructus Viticis Negundo and the Folium Microcoris paniculatae of recipe quantity, add weight is 10-12 times
The alcohol reflux of amount water or 50%-60% 2 times, each 1-2 hour.
7. a kind of Chinese medicine composition of preventing and treating diarrhea in livestock according to claim 1 is used for treating in preparation or prevents domestic animal
Application in the medicine of diarrhoea.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN115721677A (en) * | 2022-12-22 | 2023-03-03 | 北京生泰尔科技股份有限公司 | Traditional Chinese medicine composition for preventing and treating bacterial diarrhea of calves and preparation method and application thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105497878A (en) * | 2015-12-31 | 2016-04-20 | 中悦民安（北京）科技发展有限公司 | Compound preparation for treating animal diarrhea and preparation method of compound preparation |
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- 2016-10-20 CN CN201610912762.8A patent/CN106361902A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105497878A (en) * | 2015-12-31 | 2016-04-20 | 中悦民安（北京）科技发展有限公司 | Compound preparation for treating animal diarrhea and preparation method of compound preparation |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115721677A (en) * | 2022-12-22 | 2023-03-03 | 北京生泰尔科技股份有限公司 | Traditional Chinese medicine composition for preventing and treating bacterial diarrhea of calves and preparation method and application thereof |
| CN115721677B (en) * | 2022-12-22 | 2023-10-31 | 北京生泰尔科技股份有限公司 | Traditional Chinese medicine composition for preventing and treating calf bacterial diarrhea, and preparation method and application thereof |
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Application publication date: 20170201 |