CN105412892A - Traditional Chinese medicine preparation for treating diarrhea of piglets and preparation method thereof - Google Patents

Traditional Chinese medicine preparation for treating diarrhea of piglets and preparation method thereof Download PDF

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Publication number
CN105412892A
CN105412892A CN201511024709.6A CN201511024709A CN105412892A CN 105412892 A CN105412892 A CN 105412892A CN 201511024709 A CN201511024709 A CN 201511024709A CN 105412892 A CN105412892 A CN 105412892A
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chinese medicine
preparation
radix
medicine preparation
grams
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陈世西
杜长海
史競
高飞
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BEIJING RESOURCE ASIA-PACIFIC FEED TECHNOLOGY Co Ltd
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BEIJING RESOURCE ASIA-PACIFIC FEED TECHNOLOGY Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9068Zingiber, e.g. garden ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233Bupleurum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/185Magnoliopsida (dicotyledons)
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • A61K36/344Codonopsis
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/538Schizonepeta
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    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
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    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
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    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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    • A61K36/714Aconitum (monkshood)
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    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

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Abstract

The invention provides a traditional Chinese medicine preparation for treating diarrhea of piglets and a preparation method thereof. The traditional Chinese medicine preparation is mainly prepared from, by weight, 9-11 parts of radix aconiti carmichaeli, 11-13 parts of rhizoma zingiberis, 5-8 parts of cassia twigs, 14-16 parts of roasted rhizoma atractylodis macrocephalae, 15-20 parts of Chinese dates, 4-6 parts of liquorice, 8-10 parts of radix paeoniae alba, 5-7 parts of radix bupleuri, 11-13 parts of poria cocos, 11-13 parts of schizonepeta, 5-7 parts of radices sileris and 7-9 parts of codonopsis pilosula. The traditional Chinese medicine preparation is targeted to solve the problem that the piglets are cold in body and weak, body functions of the piglets are made to recover through the features that the traditional Chinese medicine preparation is capable of expelling cold and tonifying yang, and the purpose of curing diarrhea and vomit is achieved.

Description

A kind of Chinese medicine preparation for the treatment of piglet diarrhea and preparation method thereof
Technical field
The present invention relates to field of veterinary, in particular to Chinese medicine preparation that a kind of son for the treatment of is rushed down and preparation method thereof.
Background technology
Since 2010, annual winter, season in spring two, swept across a lot of pig farms in the whole nation with suckling pig vomiting, the high epidemic disease for cardinal symptom of diarrhoea, rapid onset, death rate, the safety in production on pig farm and the economic benefit of investor of raising pigs in serious threat.Usually there is vomiting in 12 hours in newborn piglet, starts diarrhoea after birth subsequently, and feces is often in yellow, brown, white etc., color differs, feces is smelt as of rotten fish, and body surface is abound with the butyrous feces of sticky hands, after diarrhoea spirit depressed, suffer from abdominal pain, dewater, die of exhaustion and die.Dissect the severe haemorrhage of visible piglet gastrointestinal tract, gastric content is frozen into milk sample, little enteral be full of yellow liquid and expand, intestinal tube is thinning, intestinal epithelial cell comes off, small intestinal, large mesenteric lymph node marrow sample swell or hyporrhea, liver enlargement, quality is hardening crisp, gollbladder dilation wall thin and in have yellow to brown bile, other internal organs have no obvious pathological changes.The diarrhoea course of disease of piglet mostly is 3-8 days, piglet mortality rate 100% after morbidity.Existing Drug therapy, abdominal cavity fluid-supplement therapy lay particular emphasis on and extend the piglet course of disease, effectively can not cure this disease of newborn piglet.
Summary of the invention
The first object of the present invention is to provide a kind of Chinese medicine preparation for the treatment of piglet diarrhea, in order to cure newborn piglet diarrhea disease, improves the survival rate of newborn piglet.
The second object of the present invention is the manufacture method providing a kind of above-mentioned Chinese medicine preparation, and Making programme is simple, can shorten the fabrication cycle of Chinese medicine preparation.
In order to realize above-mentioned purpose of the present invention, spy by the following technical solutions:
Treat a Chinese medicine preparation for piglet diarrhea, make primarily of following raw material: by weight,
Radix Aconiti Lateralis Preparata 9-11 part; Rhizoma Zingiberis 11-13 part; Ramulus Cinnamomi 5-8 part; Rhizoma Atractylodis Macrocephalae (parched) 14-16 part;
Fructus Jujubae 15-20 part; Radix Glycyrrhizae 4-6 part; Radix Paeoniae Alba 8-10 part; Radix Bupleuri 5-7 part;
Poria 11-13 part; Herba Schizonepetae 11-13 part; Radix Saposhnikoviae 5-7 part; Radix Codonopsis 7-9 part.
Radix Aconiti Lateralis Preparata is the processed goods of the daughter root of ranunculaceae plant Aconitum carmichjaelii Debx..Pungent, sweet, hot greatly.GUIXIN, kidney, spleen channel.Mend fire supporing yang, dispersing cold for relieving pain.For YANG-depletion collapse, cold extremities faint pulse, deficiency of heart-YANG, obstruction of qi in the chest and cardialgia, deficiency and coldness is vomited and diarrhoea, kidney yang deficiency, YIN-cold edema, yang deficiency diseases caused by exogenous pathogenic factor, arthralgia due to cold-dampnes.
Rhizoma Zingiberis is the dry rhizome of zingiber.Excavate rear removing fibrous root and silt, dry.Pungent, heat.Return spleen, stomach, kidney, the heart, lung meridian.Cure mainly warming spleen and stomach for dispelling cold, recuperating depleted YANG is promoted blood circulation, warming the lung to resolve fluid-retention, and for coldness and pain in the epigastrium, vomiting is had loose bowels.
Ramulus Cinnamomi is the dry twig of canella Cortex Cinnamomi.Except defoliation after gathering, dry.Acrid, sweet, warm.GUIXIN, lung, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI.For cold in blood amenorrhea, arthralgia, phlegm retention, edema.
Rhizoma Atractylodis Macrocephalae (parched) is the dry rhizome of the feverfew Rhizoma Atractylodis Macrocephalae.Excavate rear removing silt, dry or dry, then remove fibrous root.Bitter, sweet, temperature.Return spleen, stomach warp.Cure mainly invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation.
Fructus Jujubae is the dry mature fruit of Rhamnaceae plant Fructus Jujubae.Gather during fruit maturation in autumn, dry.Sweet, temperature.Return spleen, stomach, heart channel.Cure mainly invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind.For insufficiency of the spleen lack of appetite, weak loose stool.
Radix Glycyrrhizae is the dry root welding technology of glycyrrhizic legume, Glycyrrhiza inflata Bat. or Glycyrrhiza glabra L..Excavate rear removing fibrous root, dry.Sweet, flat.GUIXIN, lung, spleen, stomach warp.Cure mainly invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion is strong.
The Radix Paeoniae Alba is the dry root of ranunculaceae plant Radix Paeoniae.After excavating, clean, remove end to end and radicula, put in boiling water and boil rear removing crust, dry.Return liver, spleen channel.Cure mainly astringing YIN to stop sweating, easing the affected liver to relieve pain, suppressing liver-YANG, for blood deficiency and yellow complexion.
Radix Bupleuri is the dry root of umbelliferae bupleurum or Radix Bupeuri Scorzonerfolii..Spring, Qiu Erji excavate, removing stem and leaf and silt, dry.
Poria is the dry sclerotia of On Polyporaceae Poria.After excavating, removing silt, dries in the shade.Cure mainly promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.For edema oliguria, insufficiency of the spleen lack of appetite, has loose bowels in loose stool.
Herba Schizonepetae is the dry aerial parts of labiate Herba Schizonepetae, and it has the effect of the loose wind that induces sweat.Tap, remove impurity, dry.
Radix Saposhnikoviae is the dry root of umbelliferae Saposhnikovia divaricata, and it has expelling pathogenic wind from the body surface, removing dampness to relieve pain, relieving convulsion.Excavate the root of plant, removing fibrous root and silt, dry.
The dry root that Radix Codonopsis is Campanulaceae Radix Codonopsis, element spends Radix Codonopsis or radix codonpsis tangshen.Excavate, clean, dry.Cure mainly invigorating the spleen and replenishing QI, spleen invigorating lung benefiting, for deficiency of the spleen and lung, cardiopalmus of breathing hard, dyspnea due to deficiency is coughed.
Preferably, the Chinese medicine system for the treatment of piglet diarrhea is made primarily of following raw material: by weight,
Radix Aconiti Lateralis Preparata 10-11 part; Rhizoma Zingiberis 12-13 part; Ramulus Cinnamomi 7-8 part; Rhizoma Atractylodis Macrocephalae (parched) 15-16 part;
Fructus Jujubae 18-20 part; Radix Glycyrrhizae 5-6 part; Radix Paeoniae Alba 8-10 part; Radix Bupleuri 6-7 part;
Poria 12-13 part; Herba Schizonepetae 12-13 part; Radix Saposhnikoviae 5-7 part; Radix Codonopsis 7-9 part.
Newborn piglet intestinal growth imperfection, physical function is low, easily disease occurs, particularly suffers from diarrhoea.The dialectical theory analysis of veterinary's Chinese materia medica is thought, the main cause of newborn piglet diarrhoea, vomiting is congenital insufficiency of kidney-YANG, and dampness-heat of the liver causes dysfunction of acting as a pivot, and then occurs vomiting and dirarrhea.Therefore, regulate piglet physical function, kidney-replenishing, liver damp of dispelling, can treat diarrhea disease.
Radix Aconiti Lateralis Preparata, the Rhizoma Atractylodis Macrocephalae, Fructus Jujubae can dispel the gas of the YIN-cold of spleen kidney, and Ramulus Cinnamomi warms up liver and gall, thus the heat of Sheng Yangming, institute thinks monarch drug.
The Radix Paeoniae Alba, Radix Bupleuri depressed liver-energy dispersing and QI regulating, relieve depression of liver-QI, by the catharsis to irritability, contribute to the rising of spleen and stomach function and the secretion of bile, to keep normal digestion, absorption function, enable piglet obtain energy from food, thus improve immunocompetence and resistance against diseases.Piglet is because suffering from diarrhoea, vomitting and dewater in a large number, and its metabolic system secretion vassopressin causes its minimizing of urinating, and then causes the pent-up in vivo such as dirt, cold.Poria can diuresis decorporation, by urinating the discharge such as evil to the refuse in piglet body, poison, thus reaches the effect of cleaning Excretory system.The strong spleen lung of Radix Codonopsis, promotes piglet self internal organs and metabolic system function, facilitating digestion born fluid, supplements diarrhoea, vomits the moisture lost.So the Radix Paeoniae Alba, Radix Bupleuri, Poria, Radix Codonopsis are ministerial drug.
Radix Glycyrrhizae can nourishing YIN empty, weak, can also be in harmonious proportion the property of medicine of each medicine simultaneously, avoid the property of medicine of medicine excessively strong, so adjuvant drug.
Piglet by raw gas invasion and attack and assemble at body surface, then because of heresy victory weakened body resistance cause in pathogenic factor in the exterior invade in.Remove the cold of liver,kidney,spleen with medicine, utilize the Herba Schizonepetae of anti-pathogenic factor in the exterior and Radix Saposhnikoviae, Rhizoma Zingiberis thoroughly to be dispelled by the raw gas in piglet health, further after treatment effect, prevents from invading in raw recurrence simultaneously.So Herba Schizonepetae and Radix Saposhnikoviae, Rhizoma Zingiberis is for making medicine.
Prescription temperature compensation yang invigorating, promotes damp and falls to body surface foreign promotion, thus reach and dispel raw gas, regulate piglet physical function, realizes the object of curing diarrhoea, symptoms of emesis.
Preferably, the Chinese medicine preparation of described treatment piglet diarrhea is oral liquid.
Due to the digestive tract function imperfection of newborn piglet, digestive system is fragile, and food is searched for food inconvenience, and its food mostly is liquid food.When newborn piglet suffer from diarrhoea, the disease of vomitting time, the more difficult administration of solid drugs, oral liquid is more convenient for gavaging.
A preparation method for the Chinese medicine preparation of above-mentioned treatment piglet diarrhea, comprises the following steps:
Weigh each raw material, with soak by water, collect decocting liquid.
This preparation method flow process is simple, handled easily, and cost that can be lower, prepares medicine fast.
Preferably, the method for described decoction is: decoct repeatedly, each decoction 30-40 minute.
Repeatedly decoct and can more fully the active ingredient in filtering residue be made full use of, reduce the waste of medicine.
Preferably, after described weighing and before described decoction, also comprise: be soaked in water 30 ~ 60 minutes.
By soaking, raw material fully absorbs moisture, its cell expansion and then break, thus release cells content, so that active ingredient is dissolved in the water, improve the utilization rate of active ingredient.
Preferably, water temperature during described immersion is 60 ~ 80 DEG C.
After medical material absorbs moisture, its cell expansion is heated simultaneously, thus the speed that raising crude drug cell breaks.Soak at the water of said temperature, active ingredient dissolubility improves, and can improve further active ingredient extraction effect.
Preferably, after described weighing and before described immersion, also comprise: by broken section of described raw material pulverizing to 3 ~ 10cm.
Raw material after pulverizing, its cellularity more destroyed, broken section contacts fully with water, to soak efficiency higher, thus to be more conducive to the active ingredient in medicine to extracting.
Preferably, also comprise after described collection decocting liquid: sterilization.
The function of newborn piglet intestinal is unsound, and resistivity is to external world weak, is easily subject to the infection of antibacterial.Sterilization processing to make in raw material bacterial content reduce, and avoids that antibacterial enters intestine of young pigs and other causes the problem of disease.
Preferably, the method for described sterilization is decocting liquid 10 ~ 30 minutes described in the ultraviolet radiation utilizing 200 ~ 260nm wavelength.
Ultraviolet can realize contactless disinfecting action, thus avoids the problem of secondary pollution preparation.Ultraviolet directly acts on the molecular structure of antibacterial, makes it dead, thus reaches better bactericidal effect.Ultraviolet in above-mentioned wave-length coverage has higher bactericidal action, and germicidal efficiency is higher.Ultraviolet irradiation overlong time then wastes energy, and the too short then bactericidal effect of irradiation time reduces, and can obtain sterilization and energy-saving effect preferably at above-mentioned time range.
Preferably, the method boiled described in is: intense fire boils, and then uses slow fire boiling 30 ~ 90 minutes.
Intense fire boils and makes temperature reach 90 ~ 110 DEG C, and slow fire boiling makes temperature reach 50 ~ 70 DEG C of intense fires.Boil and the active ingredient in medicine can be made to dissociate out from medicine fast, fully and be dissolved in the water.Slow fire slowly decocts and various active ingredient is interacted fully, avoids water by the problem that rapid evaporation causes medical material to be burned and active ingredient is destroyed simultaneously.
Beneficial effect of the present invention:
The invention provides a kind of Chinese medicinal formulae for the treatment of piglet diarrhea, the cure rate of piglet diarrhea can be significantly improved.This Chinese medicinal formulae is according to veterinary's theories of Chinese materia medica, and determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, for bringing out stagnation of QI knot raw in the cause of disease-piglet body of piglet diarrhea, failure of kidney-YANG, dampness-heat of the liver, by kidney-replenishing, warming the spleen sun, the healing of warm liver and gall realization to disease.
Detailed description of the invention
Below in conjunction with embodiment, embodiment of the present invention are described in detail, but it will be understood to those of skill in the art that the following example only for illustration of the present invention, and should not be considered as limiting the scope of the invention.Unreceipted actual conditions person in embodiment, the condition of conveniently conditioned disjunction manufacturer suggestion is carried out.Agents useful for same or the unreceipted production firm person of instrument, be and can buy by commercially available the conventional products obtained.
Embodiment 1
Present embodiments provide a kind of Chinese medicine preparation for the treatment of piglet diarrhea, comprise following component:
Radix Aconiti Lateralis Preparata 9 grams; Rhizoma Zingiberis 11 grams; Ramulus Cinnamomi 5 grams; Rhizoma Atractylodis Macrocephalae (parched) 14 grams;
15 grams, Fructus Jujubae; 4 grams, Radix Glycyrrhizae; The Radix Paeoniae Alba 8 grams; Radix Bupleuri 5 grams;
11 grams, Poria; Herba Schizonepetae 11 grams; Radix Saposhnikoviae 5 grams; Radix Codonopsis 7 grams.
The preparation method of above-mentioned Chinese medicine preparation is as follows:
According to each raw material of above-mentioned weight weighing, decoct 30 minutes by 0.5 kg of water, collect decocting liquid, the Chinese medicine preparation of piglet diarrhea must be treated.Said preparation is oral agents, wait dry in the air cool after, directly piglet is gavaged, gavages three times, each 3 milliliters every day.Preparing the remaining medicinal residues of medicine juice can admix in nursing sow material, by gavaging piglet, the diarrhea and vomiting problem of sow suckling Synergistic treatment piglet.
Embodiment 2
Present embodiments provide a kind of Chinese medicine preparation for the treatment of piglet diarrhea, comprise following component:
Radix Aconiti Lateralis Preparata 11 grams; Rhizoma Zingiberis 13 grams; Ramulus Cinnamomi 8 grams; Rhizoma Atractylodis Macrocephalae (parched) 16 grams;
20 grams, Fructus Jujubae; 6 grams, Radix Glycyrrhizae; The Radix Paeoniae Alba 10 grams; Radix Bupleuri 7 grams;
13 grams, Poria; Herba Schizonepetae 13 grams; Radix Saposhnikoviae 7 grams; Radix Codonopsis 9 grams.
According to each raw material of above-mentioned weight weighing, decoct 46 minutes by 1 kg of water, collect decocting liquid, the Chinese medicine preparation of piglet diarrhea must be treated.Said preparation is oral agents, wait dry in the air cool after, directly piglet is gavaged, gavages three times, each 3 milliliters every day.
Embodiment 3
Present embodiments provide a kind of Chinese medicine preparation for the treatment of piglet diarrhea, comprise following component:
Radix Aconiti Lateralis Preparata 10 grams; Rhizoma Zingiberis 12 grams; Ramulus Cinnamomi 6 grams; Rhizoma Atractylodis Macrocephalae (parched) 15 grams;
17 grams, Fructus Jujubae; 5 grams, Radix Glycyrrhizae; The Radix Paeoniae Alba 9 grams; Radix Bupleuri 6 grams;
12 grams, Poria; Herba Schizonepetae 12 grams; Radix Saposhnikoviae 6 grams; Radix Codonopsis 8 grams.
According to each raw material of above-mentioned weight weighing, decoct 34 minutes by 1.5 kg of water, collect decocting liquid, the Chinese medicine preparation of piglet diarrhea must be treated.Said preparation is oral agents, wait dry in the air cool after, directly piglet is gavaged, gavages three times, each 3 milliliters every day.
Embodiment 4
Present embodiments provide a kind of Chinese medicine preparation for the treatment of piglet diarrhea, comprise following component:
Radix Aconiti Lateralis Preparata 10 grams; Rhizoma Zingiberis 11 grams; Ramulus Cinnamomi 6 grams; Rhizoma Atractylodis Macrocephalae (parched) 14 grams;
17 grams, Fructus Jujubae; 5 grams, Radix Glycyrrhizae; The Radix Paeoniae Alba 10 grams; Radix Bupleuri 6 grams;
13 grams, Poria; Herba Schizonepetae 12 grams; Radix Saposhnikoviae 6 grams; Radix Codonopsis 8 grams.
First, according to each raw material of above-mentioned weight weighing, decoct 30 minutes by 0.9 kg of water, after cooling, decoct 30 minutes again, collect decocting liquid, be i.e. the Chinese medicine preparation of obtained treatment piglet diarrhea.Said preparation is oral agents, wait dry in the air cool after, directly piglet is gavaged, gavages three times, each 3 milliliters every day.
Embodiment 5
Present embodiments provide a kind of Chinese medicine preparation for the treatment of piglet diarrhea, comprise following component:
Radix Aconiti Lateralis Preparata 7 grams; Rhizoma Zingiberis 12 grams; Ramulus Cinnamomi 6 grams; Rhizoma Atractylodis Macrocephalae (parched) 15 grams;
15 grams, Fructus Jujubae; 5 grams, Radix Glycyrrhizae; The Radix Paeoniae Alba 9 grams; Radix Bupleuri 6 grams;
12 grams, Poria; Herba Schizonepetae 12 grams; Radix Saposhnikoviae 6; Radix Codonopsis 8 grams.
First, according to each raw material of above-mentioned weight weighing, 30 minutes are soaked by 0.7 kg of water.
Secondly, then boil with high heat (water temperature reaches 95 ± 2 DEG C), and then with slow fire boiling 30 minutes (water temperature reaches 50 ± 3 DEG C), collect decocting liquid, be i.e. the Chinese medicine preparation of obtained treatment piglet diarrhea.Said preparation is oral agents, wait dry in the air cool after, directly piglet is gavaged, gavages three times, each 3 milliliters every day.
Embodiment 6
Present embodiments provide a kind of Chinese medicine preparation for the treatment of piglet diarrhea, comprise following component:
Radix Aconiti Lateralis Preparata 11 grams; Rhizoma Zingiberis 11 grams; Ramulus Cinnamomi 7 grams; Rhizoma Atractylodis Macrocephalae (parched) 15 grams;
17 grams, Fructus Jujubae; 5 grams, Radix Glycyrrhizae; The Radix Paeoniae Alba 8 grams; Radix Bupleuri 6 grams;
11 grams, Poria; Herba Schizonepetae 13 grams; Radix Saposhnikoviae 7; Radix Codonopsis 9 grams.
First, according to each raw material of above-mentioned weight weighing, raw material is cut into broken section of 10cm.
Secondly, with broken section of the water soaking 57 minutes of 0.5 kilogram, 72 DEG C.
Again, after above-mentioned immersion completes, first boil with high heat (water temperature reaches 100 ± 5 DEG C), then use slow fire boiling 30 minutes (water temperature reaches 55 ± 2 DEG C), collect decocting liquid.
Finally, with the ultraviolet radiation decocting liquid 10 minutes of 210 ± 30nm wavelength, i.e. the Chinese medicine preparation of obtained treatment piglet diarrhea.Said preparation is oral agents, wait dry in the air cool after, directly piglet is gavaged, gavages three times, each 3 milliliters every day.
Embodiment 7
Present embodiments provide a kind of Chinese medicine preparation for the treatment of piglet diarrhea, comprise following component:
Radix Aconiti Lateralis Preparata 9 grams; Rhizoma Zingiberis 13 grams; Ramulus Cinnamomi 7 grams; Rhizoma Atractylodis Macrocephalae (parched) 14 grams;
18 grams, Fructus Jujubae; 6 grams, Radix Glycyrrhizae; The Radix Paeoniae Alba 9 grams; Radix Bupleuri 5 grams;
13 grams, Poria; Herba Schizonepetae 13 grams; Radix Saposhnikoviae 5; Radix Codonopsis 7 grams.
First, according to each raw material of above-mentioned weight weighing, with broken section of the water soaking 57 minutes of 1.6 kilograms, 74 DEG C.
Secondly, after above-mentioned immersion completes, first boil with high heat, then use slow fire boiling 67 minutes, collect decocting liquid.
Finally, with the ultraviolet radiation decocting liquid 30 minutes of 240 ± 20nm wavelength, i.e. the Chinese medicine preparation of obtained treatment piglet diarrhea.Said preparation is oral agents, wait dry in the air cool after, directly piglet is gavaged, gavages three times, each 3 milliliters every day.
Embodiment 8
Present embodiments provide a kind of Chinese medicine preparation for the treatment of piglet diarrhea, comprise following component:
Radix Aconiti Lateralis Preparata 11 grams; Rhizoma Zingiberis 12 grams; Ramulus Cinnamomi 5 grams; Rhizoma Atractylodis Macrocephalae (parched) 15 grams;
19 grams, Fructus Jujubae; 4 grams, Radix Glycyrrhizae; The Radix Paeoniae Alba 8 grams; Radix Bupleuri 7 grams;
12 grams, Poria; Herba Schizonepetae 11 grams; Radix Saposhnikoviae 5; Radix Codonopsis 8 grams.
First, according to each raw material of above-mentioned weight weighing, with broken section of the water soaking 46 minutes of 1 kilogram, 60 DEG C.
Secondly, after above-mentioned immersion completes, first boil with high heat (water temperature reaches 105 ± 5 DEG C), then use slow fire boiling 90 minutes (water temperature reaches 66 ± 4 DEG C), collect decocting liquid.
Finally, with the ultraviolet radiation decocting liquid 30 minutes of 220 ± 30nm wavelength, i.e. the Chinese medicine preparation of obtained treatment piglet diarrhea.Said preparation is oral agents, wait dry in the air cool after, directly piglet is gavaged, gavages three times, each 3 milliliters every day.
Test example 1
Pig farm, Baoding Region, Hebei province, livestock on hand sow: 300, at the beginning of 2015 3 months, there is vomiting within 12-36 hour in the pig that farrows in delivery room, suffer from diarrhoea immediately, feces is yellow water sample, part Lycoperdon polymorphum Vitt pasty state after birth.Sick pig whole body is seriously polluted, become thin, dewater until dead, and coordinate abdominal cavity fluid infusion (normal saline of 0.9%) with antibiotic (ceftiofur), all invalid, mortality rate 100%, the course of disease is 3-8 days.
Once there is vomiting and diarrhoea in delivery room mid-March newborn pigs, then gavage the medicine juice that in the present invention, embodiment 5 obtains, medicine juice directly gavages piglet.Every hair sick newborn piglet fills with three times every day, each filling about 3 milliliters, continuous irrigation 3 days.Altogether a 60 nest-672 delivery room morbidity newborn piglet is treated at the end of four months.
Therapeutic outcome: cure 551, cure rate is 82%.Effectively but the piglet of not curing proceeds treatment, every day three times, each 3 milliliters gavage, and cures 87, total cure rate is 95%, superseded 34.
Clinical efficacy standard used in example of more than treating is:
Cure: in three days, symptom of diarrhea disappears, the clinical symptoms such as stool colour, feed intake recovers normal.
Effective: clinical symptom disappearance in three days, the character such as feces are normal, and appetite recovers poor.
Invalid: in three days, clinical symptoms does not disappear, and appetite is poor, the state of an illness is also in development, change, even death.
The foregoing is only the preferred embodiments of the present invention, be not limited to the present invention, for a person skilled in the art, the present invention can have various modifications and variations.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.

Claims (10)

1. treat a Chinese medicine preparation for piglet diarrhea, it is characterized in that, make primarily of following raw material: by weight,
Radix Aconiti Lateralis Preparata 9-11 part; Rhizoma Zingiberis 11-13 part; Ramulus Cinnamomi 5-8 part; Rhizoma Atractylodis Macrocephalae (parched) 14-16 part;
Fructus Jujubae 15-20 part; Radix Glycyrrhizae 4-6 part; Radix Paeoniae Alba 8-10 part; Radix Bupleuri 5-7 part;
Poria 11-13 part; Herba Schizonepetae 11-13 part; Radix Saposhnikoviae 5-7 part; Radix Codonopsis 7-9 part.
2. the Chinese medicine preparation for the treatment of piglet diarrhea according to claim 1, is characterized in that, makes: by weight primarily of following raw material,
Radix Aconiti Lateralis Preparata 10-11 part; Rhizoma Zingiberis 12-13 part; Ramulus Cinnamomi 7-8 part; Rhizoma Atractylodis Macrocephalae (parched) 15-16 part;
Fructus Jujubae 18-20 part; Radix Glycyrrhizae 5-6 part; Radix Paeoniae Alba 8-10 part; Radix Bupleuri 6-7 part;
Poria 12-13 part; Herba Schizonepetae 12-13 part; Radix Saposhnikoviae 5-7 part; Radix Codonopsis 7-9 part.
3. a preparation method for the Chinese medicine preparation for the treatment of piglet diarrhea according to claim 1, is characterized in that, comprise the following steps:
Weigh each raw material, with soak by water, collect decocting liquid.
4. the preparation method of the Chinese medicine preparation for the treatment of piglet diarrhea according to claim 3, is characterized in that, the method for described decoction is: decoct repeatedly, each decoction 30-40 minute.
5. the preparation method of the Chinese medicine preparation for the treatment of piglet diarrhea according to claim 3, is characterized in that, after described weighing and before described decoction, also comprises: be soaked in water 30 ~ 60 minutes.
6. the preparation method of the Chinese medicine preparation for the treatment of piglet diarrhea according to claim 5, is characterized in that, water temperature during described immersion is 60 ~ 80 DEG C.
7. the preparation method of the Chinese medicine preparation of the treatment piglet diarrhea according to claim 5 or 6, is characterized in that, after described weighing and before described immersion, also comprises: by broken section of described raw material pulverizing to 3 ~ 10cm.
8. the preparation method of the Chinese medicine preparation for the treatment of piglet diarrhea according to claim 3, is characterized in that, also comprises after collecting decocting liquid: sterilization.
9. the preparation method of the Chinese medicine preparation for the treatment of piglet diarrhea according to claim 8, is characterized in that, the method for described sterilization is decocting liquid 10 ~ 30 minutes described in the ultraviolet radiation utilizing 200 ~ 260nm wavelength.
10. the preparation method of the Chinese medicine preparation for the treatment of piglet diarrhea according to claim 3, is characterized in that, the method for described decoction is: intense fire boils, then slow fire boiling 30 ~ 90 minutes.
CN201511024709.6A 2015-12-30 2015-12-30 Traditional Chinese medicine preparation for treating diarrhea of piglets and preparation method thereof Pending CN105412892A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107050416A (en) * 2017-05-22 2017-08-18 安徽万和沣生物科技有限公司 Pure Chinese herbal medicine composition of pig vomiting and diarrhoea and preparation method thereof caused by a kind of prevention and control cold-evil plague
CN109893642A (en) * 2019-04-16 2019-06-18 重庆市畜牧科学院 The Chinese medicine composition for treating grice diarrhoea
CN110420301A (en) * 2019-08-13 2019-11-08 济源市畜产品质量监测检验中心 A kind of Chinese medicine composition and preparation method thereof for treating post-weaning diarrhea in piglet
CN116672397A (en) * 2023-06-09 2023-09-01 河南中医药大学 Traditional Chinese medicine composition for preventing and controlling African swine fever as well as synergistic process and application thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
杨松波: "附子理中汤加减治疗慢性腹泻70例", 《内蒙古中医药》 *
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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107050416A (en) * 2017-05-22 2017-08-18 安徽万和沣生物科技有限公司 Pure Chinese herbal medicine composition of pig vomiting and diarrhoea and preparation method thereof caused by a kind of prevention and control cold-evil plague
CN109893642A (en) * 2019-04-16 2019-06-18 重庆市畜牧科学院 The Chinese medicine composition for treating grice diarrhoea
CN110420301A (en) * 2019-08-13 2019-11-08 济源市畜产品质量监测检验中心 A kind of Chinese medicine composition and preparation method thereof for treating post-weaning diarrhea in piglet
CN110420301B (en) * 2019-08-13 2022-05-17 济源市畜产品质量监测检验中心 Traditional Chinese medicine composition for treating piglet weaning diarrhea and preparation method thereof
CN116672397A (en) * 2023-06-09 2023-09-01 河南中医药大学 Traditional Chinese medicine composition for preventing and controlling African swine fever as well as synergistic process and application thereof
CN116672397B (en) * 2023-06-09 2024-05-17 河南中医药大学 Traditional Chinese medicine composition for preventing and treating African swine fever as well as synergistic process and application thereof

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Application publication date: 20160323