CN104623414A - Traditional Chinese medicine composition for treating nutritional obesity - Google Patents
Traditional Chinese medicine composition for treating nutritional obesity Download PDFInfo
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- CN104623414A CN104623414A CN201510058844.6A CN201510058844A CN104623414A CN 104623414 A CN104623414 A CN 104623414A CN 201510058844 A CN201510058844 A CN 201510058844A CN 104623414 A CN104623414 A CN 104623414A
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Abstract
The invention discloses a traditional Chinese medicine composition for treating nutritional obesity. The traditional Chinese medicine composition comprises the following raw material medicines: Angelica sinensis, hawthorn, radish seed, Radix Puerariae, chicken's gizzard-membrane, pumpkin, Chinese-date, white radish, Poria cocos, radix bupleuri, mint, immature bitter orange, rheum officinale, semen cassiae, Polygonum multiflorum, semen coicis, uncaria, herba epimedii, patrinia and liquorice. The traditional Chinese medicine composition aims at the symptoms of nutritional obesity, a mode of eliminating stagnation and regulating the body function is adopted, the body circulation is promoted, fat deposition is reduced, the five organs are effectively regulated, the organ functions are improved, digestion of fat and the like is enhanced, and finally the aims of treating both symptoms and root causes and treating the obesity are achieved.
Description
Technical field
The invention belongs to medical art, relate to a kind of Chinese medicine composition, be specifically related to a kind of Chinese medicine composition for the treatment of alimentary obesity.
Background technology
The fat difference according to the cause of disease, is divided into constitutional and Secondary Obesity two class usually, and wherein constitutional obesity is divided into again Simple Obesity and water, sodium retention obesity.Simple Obesity, according to the difference of the cause of disease, is divided into again constitutional obesity, alimentary obesity.In recent years, along with the raising day by day of people's living standard, occur that the crowd of alimentary obesity is in the swift and violent trend increased.
Alimentary obesity, is also called acquired (exogenous) fat, and after mostly appearing at 20 ~ 25 years old, due to supernutrition, picked-up heat exceedes needed for self various metabolic activity process; Or because physical exertion is very few or CBR, long-term heat exhaustion reduces and causes fat.It is mainly caused by adipocyte hypertrophy and adipose cell proliferation.Alimentary obesity and many chronic diseases, as hypertension, dyslipidemias, diabetes, hyperlipemia, sleep Apnea Syndrome etc., close relation, its serious threat mankind's is healthy.
Method of weight-reducing in the market
1. cut stomach method of weight-reducing abroad, stomach is cut 1/3rd and allow appetite tail off, its shortcoming is that people will through the misery of operation, later stomach sick as early gastric cancer just can not re-treatm ent.
2. quick weight-lossing liposuction procedures
People will experience the misery of operation equally, also will undertake a certain risk in operation, and what have causes lower extremity paralysis because performing the operation.
3. keep fit through sport
Keep fit through sport and under the guidance of doctor, will carry out according to own bodies situation, blindly motion, quantity of motion is crossed conference generation and is short of physical strength, the symptoms such as hematuria.
4. to go on a diet fat-reducing
Say in tcm health preserving that people is based on grain rice, five poultrys, five to dredge be auxiliary, and great majority fat-reducing does not eat staple food, or single thin dish, will cause malnutrition year in and year out, produce new Other diseases, as apositia, and brain atrophy.
5. antiperspirant steams fat-reducing
In overheated room, perspire in a large number, the just moisture content subtracted like this, a large amount of moisture loss of people is also disadvantageous to health.
6. Instrument defatting
Use instrument vibration help fat motion, but do not have allow fat motion, almost there is no effect.
7. fat fat-reducing is pinched in massage
Such fat-reducing effect is all right, but people will bear misery, and a lot of people can adhere to.
8. Acupancture
Acupuncture can nurse one's health health, accelerates metabolism, but a lot of people dare not attempt pin fear.
9. external preparation fat-reducing
Have two kinds: one to be Fructus Capsici extract at present, it is used on skin incomparably hot, and people is difficult to bear, very large to skin irritation.Two is Radix Et Rhizoma Rhei cream, and single rhubarb preparation can only play the effect of rushing down.
At present, western medical treatment alimentary obesity mainly adopts appetite suppressant, digests and assimilates blocade, increases the medicine of energy expenditure.All there is certain side effect in these medicines, meanwhile, its price is higher, need life-time service, and this can increase serious financial burden for patient undoubtedly.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine composition for the treatment of alimentary obesity, this Chinese medicine composition is made up of plurality of Chinese component, has no side effect, and cheap, effectively can reduce the financial burden of patient.
Above-mentioned purpose of the present invention is realized by following technical proposals:
Treat a Chinese medicine composition for alimentary obesity, the crude drug of described Chinese medicine composition is made up of Radix Angelicae Sinensis, Fructus Crataegi, Semen Raphani, Radix Puerariae, Endothelium Corneum Gigeriae Galli, Fructus Cucurbitae moschatae, Fructus Jujubae, white turnip, Poria, Radix Bupleuri, Herba Menthae, Fructus Aurantii Immaturus, Radix Et Rhizoma Rhei, Semen Cassiae, Radix Polygoni Multiflori, Semen Coicis, Ramulus Uncariae Cum Uncis, Herba Epimedii, Herba Patriniae and Radix Glycyrrhizae.
Further, raw material composition and the parts by weight of making described Chinese medicine composition are: Radix Angelicae Sinensis 9-13 part, Fructus Crataegi 2-4 part, Semen Raphani 6-8 part, Radix Puerariae 20-30 part, Endothelium Corneum Gigeriae Galli 16-25 part, Fructus Cucurbitae moschatae 4-7 part, Fructus Jujubae 12-18 part, white turnip 5-12 part, Poria 3-5 part, Radix Bupleuri 13-20 part, Herba Menthae 16-30 part, Fructus Aurantii Immaturus 30-50 part, Radix Et Rhizoma Rhei 15-20 part, Semen Cassiae 9-14 part, Radix Polygoni Multiflori 10-15 part, Semen Coicis 6-10 part, Ramulus Uncariae Cum Uncis 22-30 part, Herba Epimedii 7-10 part, Herba Patriniae 4-8 part, Radix Glycyrrhizae 5-8 part.
Further, described Chinese medicine composition makes mixture, tablet, oral liquid, capsule, granule, honeyed pill or drop pill.
Further, described Chinese medicine composition is prepared according to following method:
(1) get white turnip 10 parts, the fritter being cut into 4-5cm long adds the fiery fried dry of white vinegar, smashs to pieces, for subsequent use;
(2), after Radix Puerariae is cleaned, pull out after being soaked in water 15-30 minute, dry after section, smash powdered to pieces, for subsequent use;
(3) depend on that pine torch is placed in pot low baking temperature and fries slowly, have cracker when Semen Cassiae is micro-, slightly play drum, inner in yellow, and overflow fragrance; Then, by Semen Cassiae taking the dish out of the pot cools to room temperature then; Finally, the cool Semen Cassiae to room temperature being placed in medicine mortar smashs to pieces for subsequent use;
(4) by step (1), (2), (3) after raw material for subsequent use and other crude drug fully mix, add the 10-12 water doubly of medical material gross weight, soak 30-60 minute, decoct 2 times, each 2-3 hour, filter, merging filtrate, filtrate reduced in volume is to the extractum of relative density 1.1-1.2, this relative density is the testing result under 60-65 degree Celsius, adding ethanol to alcohol content is 75% (v/v), leave standstill 30-40 hour, get supernatant, recovery ethanol concentrates, add water to 1000ml, stir evenly, subpackage, flowing steam sterilization 35min, obtain mixture.
Further, described Chinese medicine composition is prepared according to following method:
(1) get white turnip 10 parts, the fritter being cut into 4-5cm long adds the fiery fried dry of white vinegar, smashs to pieces, for subsequent use;
(2), after Radix Puerariae is cleaned, pull out after being soaked in water 15-30 minute, dry after section, smash powdered to pieces, for subsequent use;
(3) depend on that pine torch is placed in pot low baking temperature and fries slowly, have cracker when Semen Cassiae is micro-, slightly play drum, inner in yellow, and overflow fragrance; Then, by Semen Cassiae taking the dish out of the pot cools to room temperature then; Finally, the cool Semen Cassiae to room temperature being placed in medicine mortar smashs to pieces for subsequent use;
(4) after the raw material for subsequent use of step (1), (2), (3) and other crude drug fully being mixed, add the 10-15 water doubly of medical material gross weight, soak 60-100 minute, decoct 2 times, each 1 hour, filter, merging filtrate, filtrate reduced in volume is to the extractum of relative density 1.25, and this relative density is the testing result under 60-65 degree Celsius, adding ethanol to alcohol content is 85% (v/v), leave standstill 24 hours, get supernatant, reclaim ethanol to concentrated, vacuum drying, granulation, namely tabletting obtains tablet.
Further, described Chinese medicine composition is prepared according to following method:
(1) get white turnip 10 parts, the fritter being cut into 4-5cm long adds the fiery fried dry of white vinegar, smashs to pieces, for subsequent use;
(2), after Radix Puerariae is cleaned, pull out after being soaked in water 15-30 minute, dry after section, smash powdered to pieces, for subsequent use;
(3) depend on that pine torch is placed in pot low baking temperature and fries slowly, have cracker when Semen Cassiae is micro-, slightly play drum, inner in yellow, and overflow fragrance; Then, by Semen Cassiae taking the dish out of the pot cools to room temperature then; Finally, the cool Semen Cassiae to room temperature being placed in medicine mortar smashs to pieces for subsequent use;
(4) after the raw material for subsequent use of step (1), (2), (3) and other crude drug fully being mixed, add the 8-10 water doubly of medical material gross weight, soak 45-60 minute, decoct 4 times, each 1.5-2 hour, filter, merging filtrate, filtrate reduced in volume is to the extractum of relative density 1.2, this relative density is the testing result under 60-65 degree Celsius, adding ethanol to alcohol content is 90% (v/v), leaves standstill 24 hours, gets supernatant, reclaim ethanol to concentrated, vacuum drying, granulates, encapsulated.
Further, described Chinese medicine composition is prepared according to following method:
(1) get white turnip 10 parts, the fritter being cut into 4-5cm long adds the fiery fried dry of white vinegar, smashs to pieces, for subsequent use;
(2), after Radix Puerariae is cleaned, pull out after being soaked in water 15-30 minute, dry after section, smash powdered to pieces, for subsequent use;
(3) depend on that pine torch is placed in pot low baking temperature and fries slowly, have cracker when Semen Cassiae is micro-, slightly play drum, inner in yellow, and overflow fragrance; Then, by Semen Cassiae taking the dish out of the pot cools to room temperature then; Finally, the cool Semen Cassiae to room temperature being placed in medicine mortar smashs to pieces for subsequent use;
(4) after the raw material for subsequent use of step (1), (2), (3) and other crude drug fully being mixed, add 6-10 times of water gaging of medical material gross weight, decoct 2-3 hour, leach medicine juice; Add 6-10 times of water gaging again, decoct 0.5-2 hour, leach medicine juice; Merge secondary decocting liquid, leave standstill, leaching supernatant, concentrated, let cool, add concentrated solution 2-3 times amount ethanol, stir precipitates overnight; Get supernatant, be concentrated into thick extractum; Add pharmaceutic adjuvant, vacuum drying, pulverize and granulate, dry, granulate, obtains 20g granule, and subpackage 10g/ bag, obtains granule.
Further, described Chinese medicine composition is prepared according to following method:
(1) get white turnip 10 parts, the fritter being cut into 4-5cm long adds the fiery fried dry of white vinegar, smashs to pieces, for subsequent use;
(2), after Radix Puerariae is cleaned, pull out after being soaked in water 15-30 minute, dry after section, smash powdered to pieces, for subsequent use;
(3) depend on that pine torch is placed in pot low baking temperature and fries slowly, have cracker when Semen Cassiae is micro-, slightly play drum, inner in yellow, and overflow fragrance; Then, by Semen Cassiae taking the dish out of the pot cools to room temperature then; Finally, the cool Semen Cassiae to room temperature being placed in medicine mortar smashs to pieces for subsequent use;
(4) after the raw material for subsequent use of step (1), (2), (3) and other crude drug fully being mixed, add 6-9 times of water gaging of medical material gross weight, decoct 2-3 hour, leach medicine juice; Add 6-10 times of water gaging again, decoct 0.5-2 hour, leach medicine juice; Merge secondary decocting liquid, leave standstill, leaching supernatant, concentrated, let cool, add concentrated solution 2-3 times amount ethanol, stir precipitates overnight; Get supernatant, be concentrated into thick extractum; Add suitable pharmaceutical aids, make oral liquid.
The Chinese medicine composition for the treatment of alimentary obesity provided by the present invention, it for raw material, gives full play to the property of medicine of each component with common Chinese herbal medicine:
Fructus Crataegi is the fruit of Flos Rosae Multiflorae tannin plant Fructus Crataegi or Crataegi cuneatae, its acid, sweet, tepor, enters spleen, stomach, Liver Channel, have help digestion long-pending, dissipating blood stasis blood, diuresis, effect of antidiarrheal.After human body takes Fructus Crataegi, the activity of enzyme in stomach can be increased, promote food digestion, circulation of qi promoting dissipating blood stasis, be beneficial to the meat that disappears and amass.
Semen Raphani has another name called trailing plants white chessman, Semen Raphani etc., is the mature seed of crucifer Radix Raphani.It has the de-swelling that helps digestion, effect of lowering the adverse-rising QI to resolve phlegm, is mainly used in retention of food and drink, abdominal distention, constipation, stagnant dysentery, expectorant stops up and breath with cough.Effect of its de-swelling that helps digestion is remarkable, has the title of " rush wall fall wall ".
Endothelium Corneum Gigeriae Galli is sweet, flat, returns spleen, stomach, small intestinal, urinary bladder channel, has effect of strengthening the spleen to promote digestion, only incontinence of urine, the inducing decomposition of calculi, is mainly used in food stagnation and does not disappear, vomiting dysentery, infantile malnutrition etc.
Fructus Cucurbitae moschatae is sweet, warm, enters spleen, stomach warp, has warming middle-JIAO and relieving asthma, effect of parasite killing removing toxic substances.Fructus Cucurbitae moschatae has the effect of invigorating the spleen and regulating the stomach, can play the effect of invigorating the spleen and replenishing QI.
Fructus Jujubae has another name called dry Fructus Jujubae, U.S. Fructus Jujubae, good Fructus Jujubae, Fructus Jujubae, and be the mature fruit of Li Ke plant Fructus Jujubae, its property is sweet, warm, enters spleen, stomach warp.It has spleen reinforcing stomach function regulating, supplementing QI for promoting the production of body fluid, tune battalion defend, blood fat reducing, anticancer effect, can be used in treating weakness of the spleen and stomach, fatigue and weakness, blood deficiency and yellow complexion, mind is uneasy.
White turnip, have another name called Radix Raphani, reed Fu, warm ancient name for Chinese cabbage, soil shortcake, its property acrid, sweet, cool, enters lung, stomach warp, has and eliminate indigestion and phlegm, effect of therapeutic method to keep the adverse QI flowing downwards alleviating distention in middle-JIAO.Containing mustard oil and amylase in white turnip, therefore there is acid, can be aid digestion, increase appetite; Wherein also containing a certain amount of crude fibre, can promote gastrointestinal peristalsis, tonneau is defecated; Also there is relieving cough and resolving phlegm effect simultaneously, to infectious disease such as flu, meningitis, diphtheria, have certain preventive effect.
Poria: sweet in the mouth, light, property are put down, can eliminating dampness and diuresis; Invigorating the spleen and regulating the stomach; Mind tranquilizing and the heart calming.Cure mainly dysuria; Edema distension; Phlegm retention cough with dyspnea; Vomiting; Insufficiency of the spleen lack of appetite; Have loose bowels; Palpitation and restlessness; Insomnia forgetfulness; Seminal emission nebulousurine.
Radix Bupleuri: bitter, is slightly cold.Return liver, gallbladder meridian.Function cures mainly: reconciling superficies and interior, soothing the liver, yang invigorating.For cold, fever, alternate attack of chill and fever, distending pain in the chest and hypochondrium, menoxenia, sub-official's prolapsus, proctoptosis.Application: 1. for the disease such as alternate attack of chill and fever, cold, fever.Treatment is evil in few sun, alternate attack of chill and fever, and normal being equal to Radix Scutellariae, the Rhizoma Pinelliae is used; Cure cold heating, with Radix Puerariae, Gypsum Fibrosum, Radix Scutellariae compatibility.2. for depression of liver-QI, the pain over the hypochondriac region, menoxenia etc.With the medicine such as Radix Angelicae Sinensis, the Radix Paeoniae Alba, Rhizoma Cyperi, Radix Curcumae with using.3. for diseases such as collapse of QI, chronic diarrhea proctoptosis, uterine prolapses.Join Radix Codonopsis, the Radix Astragali, Rhizoma Cimicifugae etc.
Radix Glycyrrhizae: sweet in the mouth, returns 12 warps.There is removing toxic substances, eliminate the phlegm, pain relieving, spasmolytic is so that the pharmacological action such as anticancer.In the traditional Chinese medical science, Radix Glycyrrhizae invigorating the spleen and replenishing QI, grows and coughs lung moistening, and emergency is detoxified, and is in harmonious proportion hundred medicines.
Herba Menthae: acrid in the mouth, cool in nature.Return lung, Liver Channel, have and disperse wind heat, clearing throat, rash is detoxified, dispersing the stagnated live-QI to relieve the stagnation of QI and the effect such as antipruritic, be applicable to the disease such as cold, fever, headache, laryngopharynx swelling and pain, lossless, wind-fire acute conjunctivitis, rubella, skin are itched, colic, dysentery and scrofula, external has slight analgesic effect, for neuralgia etc.
Fructus Aurantii Immaturus: temperature; Bitter, pungent, sour; Return spleen, stomach warp.Dispelling the stagnated QI removing food stagnancy, loose painful abdominal mass of reducing phlegm.Stop in stagnant, feeling of fullness distending pain, heavy after dysentery, constipation, the stagnant vapour lock thoracic obstruction of expectorant, blocked-up chest, gastroptosis, proctoptosis, uterine prolapse.
Radix Et Rhizoma Rhei: be the root welding technology of polygonum rheum palmatum, Rheum tanguticum or Rheum officinale.Nature and flavor: bitter, cold.Gui Jing: stomach warp; Large intestine channel; Liver Channel; Spleen channel; Effect: attack stagnant; Clearing away damp-heat; Pathogenic fire purging; Removing heat from blood; Blood stasis dispelling; Removing toxic substances.Chemical composition: be mainly anthraquinone derivative, mainly comprises anthraquinone glycoside and dianthracene quinone glycoside.Sennoside A, B, C, D, E, F is had in dianthracene quinone glycoside; The aglycon of sequestered has chrysophanol, chrysophanic acid, emodin, aloe-emodin, physcione etc.Pharmacological action: Radix Et Rhizoma Rhei can increase enterokinesia, suppresses enteral moisture absorption, and promote defecation, Radix Et Rhizoma Rhei has anti-infectious function, all have inhibitory action to multiple Grain-positive and negative bacteria, infected by influenza also has inhibitory action, also has hemostasis in addition, protect the liver, blood pressure lowering, reduce serum cholesterol effect.
Radix Angelicae Sinensis: sweet, pungent, temperature, returns liver, heart spleen channel.Tonifying blood and regulating menstruation, promoting blood circulation and stopping pain, loosening bowel to relieve constipation.Chemical composition: containing nopinene in Radix Angelicae Sinensis, australene, the neutral oil compositions such as camphene.Containing p-methylbenzyl alcohol, the acid-soluble oil compositions such as 5-methoxyl group-2,3-xylenols, organic acid, saccharide, vitamin, aminoacid etc.Pharmacological action: Radix Angelicae Sinensis volatile oil can to antiadrenergic drug-pituitrin or histamine to the excitation in uterus, and eumenol has significantly expansion isolated guinea pig coronary effect, increases coronary flow.
Semen Cassiae bitter in the mouth, sweet, salty, cold nature, enters liver, kidney, large intestine channel; Loosening bowel to relieve constipation, blood fat reducing improving eyesight, treatment constipation and hyperlipidemia, hypertension.Liver heat removing and eyesight improving, diuretic relieving constipation, has laxative action, reducing blood pressure and blood fat.
Radix Polygoni Multiflori bitter in the mouth, sweet; Puckery, slightly warm in nature, returns liver, kidney channel.Mainly contain nourishing the blood and yin, loosening bowel to relieve constipation, preventing the attack (or recurrence) of malaria, dispel the wind, detoxify.Cure mainly blood deficiency Light-headedness, cardiopalmus, insomnia, the soreness of the waist and knees of the hepatic and renal YIN deficiency, early whitening of beard and hair, tinnitus, seminal emission, dryness of the intestine constipation, chronic malaria body void, rubella pruritus, carbuncle sore, scrofula, hemorrhoid etc.
Semen Coicis, sweet in the mouth, light, cold nature.Return spleen, stomach, lung meridian.Energy promoting diuresis to eliminate damp pathogen, damp eliminating eliminating impediment, invigorating the spleen to arrest diarrhea, clearing away heat and discharging pus.Cure mainly dysuria, edema, beriberi, arthralgia chiefly caused by damp pathogen contracture, hygropyrexia from the beginning of and the card such as diarrhea due to hypofunction of the spleen, lung abscess, acute appendicitis.
Radix Puerariae, sweet in the mouth, pungent, cool in nature.Enter spleen, stomach warp.There is yang invigorating expelling pathogenic factors from muscles, rash antidiarrheal, effect that relieving restlessness is only warm.For typhoid fever, warm headache stiffness of the nape, dysphoria with smothery sensation is quenched one's thirst, and has loose bowels, dysentery, and skin eruption is not saturating, hypertension, and angina pectoris is deaf.Be used for Hypertension neck pain, angina pectoris clinically, but also there is hypoglycemic activity.
Ramulus Uncariae Cum Uncis, sweet in the mouth, cool in nature.Enter liver, heart channel.Energy heat clearing away suppressing the hyperactive liver, relieve dizziness, high fever, infantile convulsions, epilepsy, etc. arresting convulsion.Cure mainly pediatric epilepsy scared Chi Zong, adult's slight Hypertension, dizzy, dizzy, married woman's eclamposia.Its pharmacological action has sedation and hypotensive effect.
Herba Epimedii, acrid in the mouth, sweet, warm in nature, return Liver Channel, kidney channel.Energy kidney-replenishing, bone and muscle strengthening, wind-damp dispelling.For impotence and seminal emission, muscles and bones flaccidity is soft, rheumatic arthralgia, numbness contracture; Climacteric hypertension.
Herba Patriniae: pungent, bitter, be slightly cold, enters stomach, large intestine, Liver Channel, heat-clearing and toxic substances removing, clots absorbing evacuation of pus.
This Chinese medicine composition is made up of Radix Angelicae Sinensis, Fructus Crataegi, Semen Raphani, Radix Puerariae, Endothelium Corneum Gigeriae Galli, Fructus Cucurbitae moschatae, Fructus Jujubae, white turnip, Poria, Radix Bupleuri, Herba Menthae, Fructus Aurantii Immaturus, Radix Et Rhizoma Rhei, Semen Cassiae, Radix Polygoni Multiflori, Semen Coicis, Ramulus Uncariae Cum Uncis, Herba Epimedii, Herba Patriniae, Radix Glycyrrhizae.Long-pending, the dissipating blood stasis blood of hawthorn digesting in side, Semen Raphani helps digestion effect of de-swelling, lowering the adverse-rising QI to resolve phlegm, Endothelium Corneum Gigeriae Galli strengthening the spleen to promote digestion, only incontinence of urine, the inducing decomposition of calculi, Fructus Cucurbitae moschatae invigorating the spleen and regulating the stomach, invigorating the spleen and replenishing QI, Fructus Jujubae spleen reinforcing stomach function regulating, supplementing QI for promoting the production of body fluid, tune battalion defends, blood fat reducing, white turnip eliminates indigestion and phlegm, the therapeutic method to keep the adverse QI flowing downwards is wide, monarch drug in Fructus Crataegi, Semen Raphani, Endothelium Corneum Gigeriae Galli, Fructus Cucurbitae moschatae, Fructus Jujubae, the white turnip side of being; Poria eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, Radix Bupleuri reconciling superficies and interior, soothing the liver, yang invigorating, Fructus Aurantii Immaturus dispelling the stagnated QI removing food stagnancy, loose painful abdominal mass of reducing phlegm, Chinese angelica blood supplementing regulating menstruation, promoting blood circulation and stopping pain, loosening bowel to relieve constipation, Semen Coicis promoting diuresis to eliminate damp pathogen, damp eliminating eliminating impediment, invigorating the spleen to arrest diarrhea, clearing away heat and discharging pus, Radix Polygoni Multiflori nourishing the blood and yin, loosening bowel to relieve constipation, preventing the attack (or recurrence) of malaria, dispel the wind, detoxify, Poria, Radix Bupleuri, Fructus Aurantii Immaturus, Radix Angelicae Sinensis, Semen Coicis, Radix Polygoni Multiflori are ministerial drug altogether; Herba Menthae disperses wind heat, clearing throat, rash removing toxic substances, and Radix Et Rhizoma Rhei attacks stagnant, clearing away damp-heat, pathogenic fire purging, removing heat from blood, blood stasis dispelling, removing toxic substances, Semen Cassiae loosening bowel to relieve constipation, blood fat reducing improving eyesight, Radix Puerariae yang invigorating expelling pathogenic factors from muscles, rash antidiarrheal, relieving restlessness is temperature only, also has hypoglycemic activity, Herba Epimedii kidney-replenishing, bone and muscle strengthening, wind-damp dispelling, Herba Patriniae heat-clearing and toxic substances removing, clots absorbing evacuation of pus, Herba Menthae, Radix Et Rhizoma Rhei, Semen Cassiae, Radix Puerariae, Herba Epimedii, Herba Patriniae are adjuvant drug; Ramulus Uncariae Cum Uncis heat clearing away suppressing the hyperactive liver, relieve dizziness, high fever, infantile convulsions, epilepsy, etc. arresting convulsion, Radix Glycyrrhizae invigorating the spleen and replenishing QI, grows and cough lung moistening, and emergency is detoxified, and is in harmonious proportion hundred medicines, and Ramulus Uncariae Cum Uncis, Radix Glycyrrhizae are for making medicine.All medicines share the effect reaching clearing away liver fire and reducing fat, function of spleen and stomach regulating, kidney tonifying nourishing the liver, use safety, convenient, no dependence, not only alimentary obesity tool is had significant therapeutic effect, and can also have good auxiliary therapeutic action at the other diseases such as blood pressure lowering, blood fat reducing.
At present, mainly with Western medicine or operations in treating obesity on market, adopt the fat that disappears to be main, but Western medicine side effect is large more, and easily rebounds; There is certain risk in operative treatment, costly.The present invention is directed to alimentary obesity symptom, adopt the stagnant mode with regulating body function to combine that disappears, promote body-internal-circulation on the one hand, reduce the deposition of fat, the five internal organs are effectively regulated simultaneously, improve organ function, strengthen the digestion to fat etc., finally reach treating both the principal and secondary aspects of a disease, the object that treatment is fat.Formula of the present invention is reasonable, and therapeutic effect is good, has no side effect to human body, and cost is low, can effective relieve patient ' s burden.
Detailed description of the invention
For making the object of the embodiment of the present invention, technical scheme and advantage clearly, below in conjunction with embodiment, technical scheme of the present invention is clearly and completely described.Obviously, described embodiment is a part of the present invention, instead of whole embodiments.Based on described embodiments of the invention, the every other embodiment that those of ordinary skill in the art obtain under without the need to the prerequisite of creative work, all belongs to the scope of protection of the invention.Except as otherwise noted, the percent of the amount of alcohol in the present invention is percentage by volume, and v/v represents the volume ratio of solution.
Embodiment 1:
A kind of Chinese medicine composition for the treatment of alimentary obesity of the present invention, gets following traditional Chinese medicine raw medicine: Radix Angelicae Sinensis 9 parts, Fructus Crataegi 2 parts, Semen Raphani 8 parts, Radix Puerariae 25 parts, Endothelium Corneum Gigeriae Galli 20 parts, 4 parts, Fructus Cucurbitae moschatae, 16 parts, Fructus Jujubae, white turnip 10 parts, 4 parts, Poria, Radix Bupleuri 20 parts, Herba Menthae 28 parts, Fructus Aurantii Immaturus 50 parts, Radix Et Rhizoma Rhei 15 parts, Semen Cassiae 14 parts, Radix Polygoni Multiflori 12 parts, Semen Coicis 10 parts, Ramulus Uncariae Cum Uncis 25 parts, Herba Epimedii 7 parts, Herba Patriniae 8 parts, 8 parts, Radix Glycyrrhizae.
Preparation method is:
(1) get white turnip 10 parts, be cut into the long fritter of 4-5cm add white vinegar fire fry in, smash to pieces, for subsequent use;
(2), after Radix Puerariae is cleaned, pull out after being soaked in water 15-30 minute, dry after section, smash powdered to pieces, for subsequent use;
(3) depend on that pine torch is placed in pot low baking temperature and fries slowly, have cracker when Semen Cassiae is micro-, slightly play drum, inner in yellow, and overflow fragrance; Then, by Semen Cassiae taking the dish out of the pot cools to room temperature then; Finally, the cool Semen Cassiae to room temperature being placed in medicine mortar smashs to pieces for subsequent use;
(4) by step (1), (2), (3) after raw material for subsequent use and other crude drug fully mix, add the 10-12 water doubly of medical material gross weight, soak 30-60 minute, decoct 2 times, each 2-3 hour, filter, merging filtrate, filtrate reduced in volume is to the extractum of relative density 1.1-1.2, this relative density is the testing result under 60-65 degree Celsius, adding ethanol to alcohol content is 75% (v/v), leave standstill 30-40 hour, get supernatant, recovery ethanol concentrates, add water to 1000ml, stir evenly, subpackage, flowing steam sterilization 35min, obtain mixture.
Embodiment 2:
A kind of Chinese medicine composition for the treatment of alimentary obesity of the present invention, gets following traditional Chinese medicine raw medicine: Radix Angelicae Sinensis 13 parts, Fructus Crataegi 4 parts, Semen Raphani 8 parts, Radix Puerariae 20 parts, Endothelium Corneum Gigeriae Galli 18 parts, 5 parts, Fructus Cucurbitae moschatae, 12 parts, Fructus Jujubae, white turnip 5 parts, 3.5 parts, Poria, Radix Bupleuri 16 parts, Herba Menthae 30 parts, Fructus Aurantii Immaturus 30 parts, Radix Et Rhizoma Rhei 18 parts, Semen Cassiae 9 parts, Radix Polygoni Multiflori 10 parts, Semen Coicis 6 parts, Ramulus Uncariae Cum Uncis 22 parts, Herba Epimedii 10 parts, Herba Patriniae 4 parts, 5 parts, Radix Glycyrrhizae.
Preparation method is:
(1) get white turnip 10 parts, the fritter being cut into 4-5cm long adds the fiery fried dry of white vinegar, smashs to pieces, for subsequent use;
(2), after Radix Puerariae is cleaned, pull out after being soaked in water 15-30 minute, dry after section, smash powdered to pieces, for subsequent use;
(3) depend on that pine torch is placed in pot low baking temperature and fries slowly, have cracker when Semen Cassiae is micro-, slightly play drum, inner in yellow, and overflow fragrance; Then, by Semen Cassiae taking the dish out of the pot cools to room temperature then; Finally, the cool Semen Cassiae to room temperature being placed in medicine mortar smashs to pieces for subsequent use;
(4) after the raw material for subsequent use of step (1), (2), (3) and other crude drug fully being mixed, add the 10-15 water doubly of medical material gross weight, soak 60-100 minute, decoct 2 times, each 1 hour, filter, merging filtrate, filtrate reduced in volume is to the extractum of relative density 1.25, and this relative density is the testing result under 60-65 degree Celsius, adding ethanol to alcohol content is 85% (v/v), leave standstill 24 hours, get supernatant, reclaim ethanol to concentrated, vacuum drying, granulation, namely tabletting obtains tablet.
Embodiment 3:
A kind of Chinese medicine composition for the treatment of alimentary obesity of the present invention, gets following traditional Chinese medicine raw medicine: Radix Angelicae Sinensis 10 parts, Fructus Crataegi 3 parts, Semen Raphani 6 parts, Radix Puerariae 20 parts, Endothelium Corneum Gigeriae Galli 16 parts, 7 parts, Fructus Cucurbitae moschatae, 18 parts, Fructus Jujubae, white turnip 6 parts, 3 parts, Poria, Radix Bupleuri 18 parts, Herba Menthae 18 parts, Fructus Aurantii Immaturus 40 parts, Radix Et Rhizoma Rhei 20 parts, Semen Cassiae 12 parts, Radix Polygoni Multiflori 15 parts, Semen Coicis 12 parts, Ramulus Uncariae Cum Uncis 28 parts, Herba Epimedii 8 parts, Herba Patriniae 5 parts, 3 parts, Radix Glycyrrhizae.
Preparation method is:
(1) get white turnip 10 parts, the fritter being cut into 4-5cm long adds the fiery fried dry of white vinegar, smashs to pieces, for subsequent use;
(2), after Radix Puerariae is cleaned, pull out after being soaked in water 15-30 minute, dry after section, smash powdered to pieces, for subsequent use;
(3) depend on that pine torch is placed in pot low baking temperature and fries slowly, have cracker when Semen Cassiae is micro-, slightly play drum, inner in yellow, and overflow fragrance; Then, by Semen Cassiae taking the dish out of the pot cools to room temperature then; Finally, the cool Semen Cassiae to room temperature being placed in medicine mortar smashs to pieces for subsequent use;
(4) after the raw material for subsequent use of step (1), (2), (3) and other crude drug fully being mixed, add the 8-10 water doubly of medical material gross weight, soak 45-60 minute, decoct 4 times, each 1.5-2 hour, filter, merging filtrate, filtrate reduced in volume is to the extractum of relative density 1.2, this relative density is the testing result under 60-65 degree Celsius, adding ethanol to alcohol content is 90% (v/v), leaves standstill 24 hours, gets supernatant, reclaim ethanol to concentrated, vacuum drying, granulates, encapsulated.
Embodiment 4:
A kind of Chinese medicine composition for the treatment of alimentary obesity of the present invention, gets following traditional Chinese medicine raw medicine: Radix Angelicae Sinensis 11 parts, Fructus Crataegi 2 parts, Semen Raphani 8 parts, Radix Puerariae 30 parts, Endothelium Corneum Gigeriae Galli 25 parts, 6 parts, Fructus Cucurbitae moschatae, 13 parts, Fructus Jujubae, white turnip 12 parts, 5 parts, Poria, Radix Bupleuri 13 parts, Herba Menthae 23 parts, Fructus Aurantii Immaturus 35 parts, Radix Et Rhizoma Rhei 16 parts, Semen Cassiae 14 parts, Radix Polygoni Multiflori 13 parts, Semen Coicis 8 parts, Ramulus Uncariae Cum Uncis 30 parts, Herba Epimedii 9 parts, Herba Patriniae 6 parts, 7 parts, Radix Glycyrrhizae.
Preparation method is:
(1) get white turnip 10 parts, the fritter being cut into 4-5cm long adds the fiery fried dry of white vinegar, smashs to pieces, for subsequent use;
(2), after Radix Puerariae is cleaned, pull out after being soaked in water 15-30 minute, dry after section, smash powdered to pieces, for subsequent use;
(3) depend on that pine torch is placed in pot low baking temperature and fries slowly, have cracker when Semen Cassiae is micro-, slightly play drum, inner in yellow, and overflow fragrance; Then, by Semen Cassiae taking the dish out of the pot cools to room temperature then; Finally, the cool Semen Cassiae to room temperature being placed in medicine mortar smashs to pieces for subsequent use;
(4) after the raw material for subsequent use of step (1), (2), (3) and other crude drug fully being mixed, add 6-10 times of water gaging of medical material gross weight, decoct 2-3 hour, leach medicine juice; Add 6-10 times of water gaging again, decoct 0.5-2 hour, leach medicine juice; Merge secondary decocting liquid, leave standstill, leaching supernatant, concentrated, let cool, add concentrated solution 2-3 times amount ethanol, stir precipitates overnight; Get supernatant, be concentrated into thick extractum; Add pharmaceutic adjuvant (conventionally selecting pharmaceutic adjuvant), vacuum drying, pulverize and granulate, dry, granulate, obtains 20g granule, and subpackage 10g/ bag, obtains granule.
Embodiment 5:
A kind of Chinese medicine composition for the treatment of alimentary obesity of the present invention, gets following traditional Chinese medicine raw medicine: Radix Angelicae Sinensis 12 parts, Fructus Crataegi 4 parts, Semen Raphani 7 parts, Radix Puerariae 28 parts, Endothelium Corneum Gigeriae Galli 22 parts, 4 parts, Fructus Cucurbitae moschatae, 15 parts, Fructus Jujubae, white turnip 5 parts, 3 parts, Poria, Radix Bupleuri 14 parts, Herba Menthae 16 parts, Fructus Aurantii Immaturus 45 parts, Radix Et Rhizoma Rhei 19 parts, Semen Cassiae 11 parts, Radix Polygoni Multiflori 14 parts, Semen Coicis 9 parts, Ramulus Uncariae Cum Uncis 23 parts, Herba Epimedii 7 parts, Herba Patriniae 7 parts, 8 parts, Radix Glycyrrhizae.
Preparation method is:
(1) get white turnip 10 parts, the fritter being cut into 4-5cm long adds the fiery fried dry of white vinegar, smashs to pieces, for subsequent use;
(2), after Radix Puerariae is cleaned, pull out after being soaked in water 15-30 minute, dry after section, smash powdered to pieces, for subsequent use;
(3) depend on that pine torch is placed in pot low baking temperature and fries slowly, have cracker when Semen Cassiae is micro-, slightly play drum, inner in yellow, and overflow fragrance; Then, by Semen Cassiae taking the dish out of the pot cools to room temperature then; Finally, the cool Semen Cassiae to room temperature being placed in medicine mortar smashs to pieces for subsequent use;
(4) after the raw material for subsequent use of step (1), (2), (3) and other crude drug fully being mixed, add 6-9 times of water gaging of medical material gross weight, decoct 2-3 hour, leach medicine juice; Add 6-10 times of water gaging again, decoct 0.5-2 hour, leach medicine juice; Merge secondary decocting liquid, leave standstill, leaching supernatant, concentrated, let cool, add concentrated solution 2-3 times amount ethanol, stir precipitates overnight; Get supernatant, be concentrated into thick extractum; Add suitable pharmaceutical aids (conventionally selecting pharmaceutic adjuvant), can be made into oral liquid.
In addition, the Chinese medicine composition of the described treatment alimentary obesity of above-described embodiment 1-5 also can adopt conventional method to be prepared into the different pharmaceutical such as honeyed pill, drop pill version.
Acute toxicity test:
Get rat 40, be divided into 2 groups at random by body weight: granule group takes granule prepared by the embodiment of the present invention 4, and fasting is after 12 hours, by the dose gastric infusion of 10g/kg, every day twice, matched group takes distilled water, three times on the one, to observation post administration 14 days, none is dead for rat, and main organs no abnormality seen also has no other obviously extremely, within 14th day, put to death and cut open inspection part rat, perusal main organs no abnormality seen.
Six months long term toxicity tests: weigh weekly once during administration, every day claims appetite, without dead or moribund animals, measures the indexs such as rat body weight, cardiac function, liver function, renal function, electrocardiogram, administration group compares with matched group respectively, shows no obvious abnormalities.The internal organs such as the pathological examination heart, liver,kidney,spleen, lung, Stomach duodenum, large intestine, small intestinal, adrenal gland and genitals, administration group compares with matched group respectively, is showed no obvious toxic and changes.Above result points out this Chinese medicine composition safety non-toxic, can be used for clinical.
Clinical trial:
In order to verify the effect of Chinese medicine composition of the present invention, in January, 2012 in JIUYUE ,-2013, under the guidance of Shandong internal medicine in hospital expert, the routine alimentary obesity patient of outpatient service place Stochastic choice 300, Mild Obesity 60 example, central obesity 154 example, severe simple obesity 86 example, age in 16-34 year, 26.1 years old mean age.300 routine patients are divided into six groups at random, and concrete classified data is as follows:
The clinical physical data of table 1:
Diagnosis and criterion of therapeutical effect:
Diagnostic criteria: according to " practical internal medicine " regulation, 20% [standard body weight=(height-100) cm × 0.9] of the body weight that is above standard or Body Mass Index are greater than 24.
Fat division and criterion of therapeutical effect: with reference to national combination of Chinese and Western medicine obesity in 1987
The Simple Obesity curative effect judging standard that research seminar is determined.
Mild Obesity: be above standard body weight 20 ~ 30%.
Central obesity: be above standard body weight 30 ~ 50%.
Severe simple obesity: the body weight that is above standard is greater than 50%.
Curative effect judging standard is:
Effective: weight loss >=10kg, waistline minimizing >=10cm.
Effective: weight loss >=3kg, waistline minimizing >=4cm.
Invalid: weight loss < 3kg, waistline reduces < 4cm.
Therapeutic Method; 1-5 group takes the medicine of embodiment of the present invention 1-5, is equivalent to crude drug 12 grams at every turn, every day sooner or later twice one after each meal, matched group is not taken medicine, treatment group 1-5 group and matched group to diet, move all without particular/special requirement.Statistics fat-reducing result after one month, the results are shown in Table 2:
The comparison (%) of the clinical each group of curative effect of table 2
| Group | Number of cases N | Effective | Effectively | Invalid | Total effective rate (%) |
| Embodiment 1 | 50 | 8 | 33 | 9 | 82％ |
| Embodiment 2 | 50 | 9 | 32 | 9 | 82％ |
| Embodiment 3 | 50 | 8 | 35 | 7 | 86％ |
| Embodiment 4 | 50 | 11 | 30 | 9 | 82％ |
| Embodiment 5 | 50 | 10 | 32 | 8 | 84％ |
| Matched group | 50 | 0 | 0 | 0 | 0％ |
Take in process, treatment group embodiment 1-5 is without any side effects, without untoward reaction such as vomitting, suffer from diarrhoea, be nervous.
As can be seen from Table 2, the treatment group of each embodiment 1-5 is apparently higher than matched group on fat-reducing effect, and total effective rate is at least 82%.Illustrate that Chinese medicine composition provided by the invention has significantly treatment and control action for alimentary obesity.
Last it is noted that above embodiment is only in order to illustrate technical scheme of the present invention, be not intended to limit; Although with reference to previous embodiment to invention has been detailed description, those of ordinary skill in the art is to be understood that: it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature; And these amendments or replacement, do not make the essence of appropriate technical solution depart from the scope of various embodiments of the present invention technical scheme.
Claims (8)
1. treat a Chinese medicine composition for alimentary obesity, it is characterized in that: the crude drug of described Chinese medicine composition is made up of Radix Angelicae Sinensis, Fructus Crataegi, Semen Raphani, Radix Puerariae, Endothelium Corneum Gigeriae Galli, Fructus Cucurbitae moschatae, Fructus Jujubae, white turnip, Poria, Radix Bupleuri, Herba Menthae, Fructus Aurantii Immaturus, Radix Et Rhizoma Rhei, Semen Cassiae, Radix Polygoni Multiflori, Semen Coicis, Ramulus Uncariae Cum Uncis, Herba Epimedii, Herba Patriniae and Radix Glycyrrhizae.
2. the Chinese medicine composition for the treatment of alimentary obesity according to claim 1, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine composition are: Radix Angelicae Sinensis 9-13 part, Fructus Crataegi 2-4 part, Semen Raphani 6-8 part, Radix Puerariae 20-30 part, Endothelium Corneum Gigeriae Galli 16-25 part, Fructus Cucurbitae moschatae 4-7 part, Fructus Jujubae 12-18 part, white turnip 5-12 part, Poria 3-5 part, Radix Bupleuri 13-20 part, Herba Menthae 16-30 part, Fructus Aurantii Immaturus 30-50 part, Radix Et Rhizoma Rhei 15-20 part, Semen Cassiae 9-14 part, Radix Polygoni Multiflori 10-15 part, Semen Coicis 6-10 part, Ramulus Uncariae Cum Uncis 22-30 part, Herba Epimedii 7-10 part, Herba Patriniae 4-8 part, Radix Glycyrrhizae 5-8 part.
3. the Chinese medicine composition for the treatment of alimentary obesity according to claim 1 and 2, is characterized in that: described Chinese medicine composition makes mixture, tablet, oral liquid, capsule, granule, honeyed pill or drop pill.
4. the Chinese medicine composition for the treatment of alimentary obesity according to claim 2, is characterized in that: described Chinese medicine composition is prepared according to following method:
(1) get white turnip 10 parts, the fritter being cut into 4-5cm long adds the fiery fried dry of white vinegar, smashs to pieces, for subsequent use;
(2), after Radix Puerariae is cleaned, pull out after being soaked in water 15-30 minute, dry after section, smash powdered to pieces, for subsequent use;
(3) depend on that pine torch is placed in pot low baking temperature and fries slowly, have cracker when Semen Cassiae is micro-, slightly play drum, inner in yellow, and overflow fragrance; Then, by Semen Cassiae taking the dish out of the pot cools to room temperature then; Finally, the cool Semen Cassiae to room temperature being placed in medicine mortar smashs to pieces for subsequent use;
(4) by step (1), (2), (3) after raw material for subsequent use and other crude drug fully mix, add the 10-12 water doubly of medical material gross weight, soak 30-60 minute, decoct 2 times, each 2-3 hour, filter, merging filtrate, filtrate reduced in volume is to the extractum of relative density 1.1-1.2, this relative density is the testing result under 60-65 degree Celsius, adding ethanol to alcohol content is 75% (v/v), leave standstill 30-40 hour, get supernatant, recovery ethanol concentrates, add water to 1000ml, stir evenly, subpackage, flowing steam sterilization 35min, obtain mixture.
5. the Chinese medicine composition for the treatment of alimentary obesity according to claim 2, is characterized in that: described Chinese medicine composition is prepared according to following method:
(1) get white turnip 10 parts, the fritter being cut into 4-5cm long adds the fiery fried dry of white vinegar, smashs to pieces, for subsequent use;
(2), after Radix Puerariae is cleaned, pull out after being soaked in water 15-30 minute, dry after section, smash powdered to pieces, for subsequent use;
(3) depend on that pine torch is placed in pot low baking temperature and fries slowly, have cracker when Semen Cassiae is micro-, slightly play drum, inner in yellow, and overflow fragrance; Then, by Semen Cassiae taking the dish out of the pot cools to room temperature then; Finally, the cool Semen Cassiae to room temperature being placed in medicine mortar smashs to pieces for subsequent use;
(4) after the raw material for subsequent use of step (1), (2), (3) and other crude drug fully being mixed, add the 10-15 water doubly of medical material gross weight, soak 60-100 minute, decoct 2 times, each 1 hour, filter, merging filtrate, filtrate reduced in volume is to the extractum of relative density 1.25, and this relative density is the testing result under 60-65 degree Celsius, adding ethanol to alcohol content is 85% (v/v), leave standstill 24 hours, get supernatant, reclaim ethanol to concentrated, vacuum drying, granulation, namely tabletting obtains tablet.
6. the Chinese medicine composition for the treatment of alimentary obesity according to claim 2, is characterized in that: described Chinese medicine composition is prepared according to following method:
(1) get white turnip 10 parts, the fritter being cut into 4-5cm long adds the fiery fried dry of white vinegar, smashs to pieces, for subsequent use;
(2), after Radix Puerariae is cleaned, pull out after being soaked in water 15-30 minute, dry after section, smash powdered to pieces, for subsequent use;
(3) depend on that pine torch is placed in pot low baking temperature and fries slowly, have cracker when Semen Cassiae is micro-, slightly play drum, inner in yellow, and overflow fragrance; Then, by Semen Cassiae taking the dish out of the pot cools to room temperature then; Finally, the cool Semen Cassiae to room temperature being placed in medicine mortar smashs to pieces for subsequent use;
(4) after the raw material for subsequent use of step (1), (2), (3) and other crude drug fully being mixed, add the 8-10 water doubly of medical material gross weight, soak 45-60 minute, decoct 4 times, each 1.5-2 hour, filter, merging filtrate, filtrate reduced in volume is to the extractum of relative density 1.2, this relative density is the testing result under 60-65 degree Celsius, adding ethanol to alcohol content is 90% (v/v), leaves standstill 24 hours, gets supernatant, reclaim ethanol to concentrated, vacuum drying, granulates, encapsulated.
7. the Chinese medicine composition for the treatment of alimentary obesity according to claim 2, is characterized in that: described Chinese medicine composition is prepared according to following method:
(1) get white turnip 10 parts, the fritter being cut into 4-5cm long adds the fiery fried dry of white vinegar, smashs to pieces, for subsequent use;
(2), after Radix Puerariae is cleaned, pull out after being soaked in water 15-30 minute, dry after section, smash powdered to pieces, for subsequent use;
(3) depend on that pine torch is placed in pot low baking temperature and fries slowly, have cracker when Semen Cassiae is micro-, slightly play drum, inner in yellow, and overflow fragrance; Then, by Semen Cassiae taking the dish out of the pot cools to room temperature then; Finally, the cool Semen Cassiae to room temperature being placed in medicine mortar smashs to pieces for subsequent use;
(4) after the raw material for subsequent use of step (1), (2), (3) and other crude drug fully being mixed, add 6-10 times of water gaging of medical material gross weight, decoct 2-3 hour, leach medicine juice; Add 6-10 times of water gaging again, decoct 0.5-2 hour, leach medicine juice; Merge secondary decocting liquid, leave standstill, leaching supernatant, concentrated, let cool, add concentrated solution 2-3 times amount ethanol, stir precipitates overnight; Get supernatant, be concentrated into thick extractum; Add pharmaceutic adjuvant, vacuum drying, pulverize and granulate, dry, granulate, obtains 20g granule, and subpackage 10g/ bag, obtains granule.
8. the Chinese medicine composition for the treatment of alimentary obesity according to claim 2, is characterized in that: described Chinese medicine composition is prepared according to following method:
(1) get white turnip 10 parts, the fritter being cut into 4-5cm long adds the fiery fried dry of white vinegar, smashs to pieces, for subsequent use;
(2), after Radix Puerariae is cleaned, pull out after being soaked in water 15-30 minute, dry after section, smash powdered to pieces, for subsequent use;
(3) depend on that pine torch is placed in pot low baking temperature and fries slowly, have cracker when Semen Cassiae is micro-, slightly play drum, inner in yellow, and overflow fragrance; Then, by Semen Cassiae taking the dish out of the pot cools to room temperature then; Finally, the cool Semen Cassiae to room temperature being placed in medicine mortar smashs to pieces for subsequent use;
(4) after the raw material for subsequent use of step (1), (2), (3) and other crude drug fully being mixed, add 6-9 times of water gaging of medical material gross weight, decoct 2-3 hour, leach medicine juice; Add 6-10 times of water gaging again, decoct 0.5-2 hour, leach medicine juice; Merge secondary decocting liquid, leave standstill, leaching supernatant, concentrated, let cool, add concentrated solution 2-3 times amount ethanol, stir precipitates overnight; Get supernatant, be concentrated into thick extractum; Add suitable pharmaceutical aids, make oral liquid.
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| CN107519275A (en) * | 2017-06-28 | 2017-12-29 | 邢侠 | Chinese medicine composition for lowering blood-fat and reducing weight and preparation method thereof |
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