CN111588828A - Chinese medicinal preparation for treating new coronavirus and viral diseases, and its preparation method - Google Patents

Chinese medicinal preparation for treating new coronavirus and viral diseases, and its preparation method Download PDF

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CN111588828A
CN111588828A CN202010461885.0A CN202010461885A CN111588828A CN 111588828 A CN111588828 A CN 111588828A CN 202010461885 A CN202010461885 A CN 202010461885A CN 111588828 A CN111588828 A CN 111588828A
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chinese medicine
new coronavirus
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李燕
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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    • A61K36/238Saposhnikovia
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    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
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    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
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    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
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    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
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    • A61K36/725Ziziphus, e.g. jujube
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
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    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9068Zingiber, e.g. garden ginger
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    • A61K2236/30Extraction of the material
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    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

Abstract

The invention discloses a Chinese medicinal preparation for treating new coronavirus and viral diseases and a preparation method thereof, wherein the Chinese medicinal preparation is prepared from at least the following Chinese medicinal raw materials: mix-fried ephedra herb, almond, honeysuckle, gypsum, ginger, rhizoma atractylodis, oldenlandia diffusa, fructus aurantii, poria cocos, Chinese date, medicated leaven, divaricate saposhnikovia root, rheum officinale, cassia twig, platycodon grandiflorum, ligusticum chuanxiong hort, fineleaf schizonepeta herb, largehead atractylodes rhizome and honey-fried licorice root. The invention has reasonable compatibility, conforms to the specification of pharmacopoeia, is a pure Chinese medicinal prescription, has the effects of eliminating evil, nourishing stomach and not damaging stomach, has no side effect, treats both symptoms and root causes, has good curative effect on treating the early stage and the middle stage of novel coronavirus and suspected patients, has the clinically effective cure rate of 98 percent, can prevent the novel coronavirus, has good curative effect on treating epidemic viral infectious diseases, and has the effective cure rate of 98 percent. The prescription is convenient to take, free of peculiar smell and convenient to popularize and apply.

Description

Chinese medicinal preparation for treating new coronavirus and viral diseases, and its preparation method
Technical Field
The invention relates to the technical field of traditional Chinese medicine compositions, in particular to a traditional Chinese medicine preparation for treating new coronavirus and viral diseases and a preparation method thereof.
Background
The 2019 novel coronavirus is provisionally named 2019-nCoV coronavirus (new coronavirus for short) and is a new coronavirus strain discovered in human bodies in 2019. The symptoms of the virus are fever, hypodynamia, dry cough and gradual dyspnea, and severe patients show acute respiratory distress syndrome, septic shock, metabolic acidosis and blood coagulation dysfunction which are difficult to correct. The virus is confirmed to have a phenomenon of human transmission, and the latent period is infectious.
Because no medicine for effectively treating the novel coronavirus pneumonia exists at present, basic, supportive and symptomatic treatment is generally adopted in clinic. Taking a novel diagnosis and treatment scheme for coronavirus pneumonia (trial seventh edition) prepared by the national health and wellness Committee as a guiding principle, the medicine is selected according to clinical symptoms of patients, and antiviral drugs such as Reidcisvir, lopinavir, ritonavir, a-interferon and ribavirin, antifungal drugs and hormone drugs can be used. The treatment basis of the western medicines is as follows: the virus is killed. When the virus enters respiratory tract, the first meridian invaded by the virus is the solar meridian and simultaneously enters lung, the virus does not exist independently, the virus can be stuck on epithelial cells of lung to be latent at the initial stage, alveoli have virus, the virus has oxygen and body fluid nutrient substances in the lung and has life vitality, the virus is multiplied and gradually invades the lung function, some patients can suffer from fever, cough, lung body fluid is consumed to be invaded in the lung to be transformed into pneumonia, and the condition of some patients suffering from non-uniform fever further deteriorates direct lung failure.
According to the clinical manifestations and the pathogenic characteristics of the novel coronavirus pneumonia, the traditional Chinese medicine belongs to the category of epidemic febrile disease in the traditional Chinese medicine. In the pestilence treatise, it is said that the disease caused by fuwen epidemic is not wind, cold, summer-heat or damp, and there is a feeling of strange qi in the world. The epidemic toxin is mainly damp, most students consider that the name of the traditional Chinese medicine disease is 'damp toxin epidemic', and the students consider that the epidemic situation is accompanied by cold, damp and cold climate, and also can be called 'cold epidemic', but the key cause is not limited to 'damp toxin'.
The theory of traditional Chinese medicine is as follows: holistic concept, treatment based on syndrome differentiation. In the treatment of diseases, the mental state of the whole body, the circulation of qi and blood in the five zang-organs and six fu-organs, the relationship between them, the correspondence between heaven and earth, the change of seasons and the relationship between nature and nature are considered.
The epidemic situation in traditional Chinese medicine is as follows: including plague, epidemic, viral, and extremely contagious diseases are collectively called epidemic.
The evil in traditional Chinese medicine is as follows: all pathogenic factors are generally called pathogens.
The principle of traditional Chinese medicine treatment is as follows: gives an outlet for pathogenic factors (viruses) and discharges the viruses out of the body.
The invention treats both symptoms and root causes of acute diseases, and the traditional Chinese medicine preparation treats both principal and secondary aspects of diseases.
Disclosure of Invention
In order to solve the defects in the prior art, the invention provides a traditional Chinese medicine preparation for treating new coronavirus and viral diseases and a preparation method thereof.
The Chinese medicinal preparation of the invention is expressed according to the symptoms of the novel coronavirus epidemic disease: exterior cold and interior heat syndrome, and its onset symptoms in the human body in sequence: asthenia, general weakness, headache, general pain; cough, dry throat, yellow sputum; a series of symptoms such as fever, shortness of breath, pneumonia, high fever and the like provide a prescription: exterior-interior relieving, heat-clearing and detoxicating, and resisting virus. The traditional Chinese medicine prescription: the method of sweating discharges the virus inhaled by the lung out of the body along with sweat, which is equivalent to instantly replacing the body fluid of the lung infected with the virus and simultaneously replenishing the body fluid of the lung, which is equivalent to instantly cleaning the lung once (which is equivalent to washing the lung in western medicine). Further has effects of relieving fever, clearing lung-heat, recovering appetite, and descending to digestive tract to discharge virus part out of body through stool and urine to cure diseases.
In order to achieve the purpose, the technical scheme of the invention is as follows:
a traditional Chinese medicine preparation for treating new coronavirus and viral diseases comprises the following traditional Chinese medicine raw materials by weight: 3-230 g of mix-fried ephedra herb, 5-250 g of almond, 10-360 g of honeysuckle flower, 10-360 g of gypsum, 3-230 g of ginger, 10-360 g of rhizoma atractylodis, 10-360 g of oldenlandia diffusa, 5-250 g of fructus aurantii, 10-360 g of poria cocos, 10-500 g of Chinese date, 10-500 g of medicated leaven, 10-360 g of divaricate saposhnikovia root, 5-250 g of rheum officinale, 10-360 g of cassia twig, 12-380 g of platycodon grandiflorum, 5-250 g of ligusticum chuanxiong hort, 3-230 g of schizonepeta, 10-230 g of bighead atractylodes rhizome and 6-280 g of honey-fried licorice root.
Preferably, the traditional Chinese medicine composition comprises the following traditional Chinese medicine raw materials by weight: 10-120 g of mix-fried ephedra, 20-150 g of almond, 30-100 g of honeysuckle, 30-120 g of gypsum, 10-120 g of ginger, 30-180 g of rhizoma atractylodis, 30-160 g of oldenlandia diffusa, 20-150 g of fructus aurantii, 30-150 g of poria cocos, 30-300 g of Chinese date, 20-200 g of medicated leaven, 20-180 g of radix sileris, 20-120 g of rheum officinale, 20-200 g of cassia twig, 30-330 g of platycodon grandiflorum, 20-200 g of ligusticum chuanxiong hort, 10-100 g of schizonepeta, 30-200 g of rhizoma atractylodis macrocephalae and 20-230 g of honey-fried licorice root.
Preferably, the traditional Chinese medicine composition comprises the following traditional Chinese medicine raw materials by weight: 10g of mix-fried ephedra herb, 30g of almond, 30g of honeysuckle, 35g of gypsum, 20g of ginger, 30g of rhizoma atractylodis, 30g of spreading hedyotis herb, 25g of fructus aurantii, 40g of tuckahoe, 80g of Chinese date, 20g of medicated leaven, 35g of radix sileris, 40g of rhubarb, 30g of cassia twig, 30g of platycodon grandiflorum, 35g of ligusticum chuanxiong hort, 20g of schizonepeta, 40g of bighead atractylodes rhizome and 30g of honey-fried licorice root.
Preferably, the product form of the traditional Chinese medicine preparation is one of the following dosage forms: decoction, granule, and watered pill.
Preferably, the preparation method of the decoction comprises the following steps: weighing the traditional Chinese medicines according to the weight parts, adding clear water which is 10-15 times of the total weight of the raw materials, firstly soaking for 30-50 min, then boiling with strong fire, slightly boiling for 10-30 min, and then filtering to obtain a liquid; putting the medicinal residues into clear water with the weight 8-15 times of the total weight of the raw material medicines, boiling with strong fire, decocting with slow fire for 15-25 min, and filtering to obtain a filtrate; then putting the dregs into clear water with the weight 6-10 times of the total weight of the raw materials, boiling with strong fire, decocting with slow fire for 10-25 min, and filtering to obtain a filtrate; mixing the three decoctions, and packaging the mixed decoctions into 200ml bags.
Preferably, the preparation method of the water pill comprises the following steps: weighing the traditional Chinese medicines according to the formula, processing according to a conventional method, mixing, drying, crushing to 0.4-0.6 cm, sieving to obtain fine powder, adding a proper amount of water, and shaking to prepare the water pills.
The invention also aims to provide the application of the traditional Chinese medicine preparation in the medicines for treating the new coronavirus.
The invention also aims to provide the application of the traditional Chinese medicine preparation in medicines for treating viral diseases, infectious diseases and epidemic diseases.
Preferably, the viral disease is a viral cold or a respiratory viral infection and the infectious disease is a bacterial cold.
The raw materials in the formula of the invention have the following effects:
the moxibustion ephedra herb and the cassia twig are pungent, warm and divergent medicines, and have the function of dispersing virus pathogenic qi in vitro; gypsum Fibrosum and radix et rhizoma Rhei is purgative and cold-type medicine (with balanced cold and heat), and has effect in expelling virus; the bighead atractylodes rhizome and the poria cocos are medicines for invigorating stomach and eliminating dampness, and have the functions of tonifying spleen, eliminating dampness and improving gastrointestinal functions; the Chinese dates and the medicated leaven are medicines for nourishing the stomach, tonifying qi and helping digestion, and have the functions of tonifying the stomach and qi and protecting the spleen and the stomach; the divaricate saposhnikovia root and the fineleaf schizonepeta herb are medicines for dispelling wind and dispersing wind evil, and can dispel all wind evil in vivo and in vitro; honeysuckle and glossogyne haplocalyx are heat-clearing and detoxifying medicines, and can dispel all internal fire toxin; the atractylodes rhizome and the bitter orange are medicines for regulating qi and activating collaterals, and the functions of the atractylodes rhizome and the bitter orange can dredge qi activity in human bodies so that the medicine can reach pathogenic factors; the ligusticum wallichii and the platycodon grandiflorum are medicines for regulating qi and promoting qi circulation, and the functions of the medicines can dredge qi of upper and lower triple energizers and tail ends of limbs of a human body, so that the qi of the whole body is smooth, and the medicine property can reach the pathogenic part; the ginger and the almond are medicines for relieving cough, moistening lung and warming lung, and have the functions of repairing the lung invaded by virus, relieving cough, moistening lung, warming lung, nourishing lung and recovering normal lung function; the prepared licorice root is a medicine for tonifying qi, moistening lung and relieving cough, and the effect of the prepared licorice root can coordinate the properties of the medicines, so that the traditional Chinese medicines coordinate the medicine properties, the cold and heat of the medicine properties can not tonify and purge too much or too little, the medicine properties are balanced, and the healthy qi of a human body can not be injured. The Chinese medicinal preparation prepared by mutually matching the raw materials can treat novel coronavirus, can treat pestilence and epidemic viral diseases such as influenza, can remove virus and prevent internal heat from rebounding, and has the function of protecting stomach.
Compared with the prior art, the invention has the following technical effects:
the traditional Chinese medicine preparation formula is prepared by referring to the reduction and cutting of the Daqinglong decoction in the Shangqing treatise on the typhoid fever of the classical book of Zhang Zhongjing of traditional Chinese medicine, has reasonable compatibility of medicines, conforms to the regulations of pharmacopoeia, is a pure traditional Chinese medicine formula, has the effects of eliminating evil, nourishing stomach and not damaging stomach, has no side effect, treats both symptoms and root causes, has good curative effect on treating the early and middle stages of novel coronavirus and suspected patients, has the clinically effective cure rate as high as 98 percent, can prevent the novel coronavirus (if suspected to be contacted with the novel coronavirus), and has good curative effect on treating influenza, viral diseases and infectious diseases such as viral cold fever, bacterial cold, acute upper respiratory tract infection, respiratory tract virus infection, influenza, gastrointestinal type cold fever, exogenous fever with food retention and fever or influenza without fever and other infectious diseases, the effective cure rate is as high as 98 percent. The prescription is convenient to take, free of peculiar smell and convenient to popularize and apply.
Detailed Description
The present invention will be further illustrated with reference to the following specific examples.
The Chinese medicinal preparation comprises the following components: modified Daqinglong Tang; daqinglong decoction comes from Shang Han Lun. The properties, the channels, the efficacies and the main treatment functions of a single Chinese medicament are as follows:
roasting ephedra: pungent-warm exterior-releasing herbs, property-flavor entering meridian: it is pungent, slightly bitter and warm in property and enters lung and bladder meridians. The efficacy is as follows: induce sweating to relieve exterior syndrome, ventilate lung and relieve asthma, induce diuresis to alleviate edema. The main treatment is as follows: can be used for treating wind-cold type common cold, cough, asthma, edema, rheumatalgia, dorsal furuncle, and phlegm nodule. The function is as follows: has the functions of resisting inflammation, relieving asthma, inducing sweat, promoting urination and resisting pathogenic microorganisms.
Almond: the Chinese traditional medicine for treating cough has the following properties and flavors: slightly warm, sweet in flavor, entering lung and large intestine meridians. The efficacy is as follows: relieve cough and asthma, moisten intestines to relieve constipation. The main treatment is as follows: can be used for treating cough, asthma, intestinal dryness and constipation. The function is as follows: has antiasthmatic, lung moistening, lung function improving, immunity improving, and antitumor effects.
Honeysuckle flower: chinese herbs in Gui Qing Jie category, the nature, flavor and channel tropism: sweet and cold in nature, it enters lung, stomach and large intestine meridians. The efficacy is as follows: clearing away heat and toxic material, and dispelling wind and heat. The main treatment is as follows: can be used for treating affection of exogenous wind-heat, epidemic febrile disease, fever, carbuncle, swelling, sore and ulcer, sore throat, and dysentery due to toxic heat. The function is as follows: anti-inflammatory, detoxicating, protecting liver, and regulating immunity.
Gypsum: the Chinese herbs entering qi-clearing and fire-purging herbs have the following properties: sweet, bitter and cold in nature; it enters lung and stomach meridians. The efficacy is as follows: clear heat and purge fire, relieve restlessness and quench thirst. The main treatment is as follows: can be used for treating warm, high fever, polydipsia, cough due to lung heat, stomach fire, headache, and gingival swelling and pain. The function is as follows: has antiinflammatory, analgesic, and antipyretic effects.
Ginger: the interior-warming traditional Chinese medicines have the following properties, flavors and meridians-entering: pungent and hot herbs enter spleen, stomach, heart and lung meridians. The efficacy is as follows: warming the middle energizer to dispel cold, restoring yang to activate collaterals, warming the lung to resolve retained fluid. The main treatment is as follows: can be used for treating abdominal cold pain, emesis, diarrhea, yang exhaustion, cold limbs, slight phlegm, retained fluid, cough and asthma. The function is as follows: has effects of resisting inflammation, relieving pain, tranquilizing mind, and enhancing anoxia tolerance and blood coagulation resistance.
Rhizoma atractylodis: the traditional Chinese medicines for relaxing tendons and activating collaterals have the following properties and flavors: pungent, bitter and warm; it enters spleen and stomach meridians. The efficacy is as follows: eliminating dampness, invigorating spleen, removing filth, and dispelling pathogenic wind and dampness. The main treatment is as follows: can be used for treating damp stagnation, abdominal distention, emesis, wind-cold swelling and pain, common cold due to wind-cold evil, and night blindness. The function is as follows: has antibacterial, hepatoprotective, antiarrhythmic, and blood sugar lowering effects.
White hop: the heat-clearing and detoxifying traditional Chinese medicines have the following properties and flavors: sweet, bland and slightly cold, entering lung, large intestine, bladder, small intestine and stomach meridians. The functions are as follows: clearing away heat and toxic material, resolving carbuncle, dispersing pathogen accumulation, inducing diuresis and removing dampness. The main treatment is as follows: lung abscess, intestinal abscess, sore, furuncle, swelling and pain, snake venom bite. The function is as follows: it can be used for treating gastric cancer, pulmonary abscess, intestinal abscess, damp-heat-toxin, cancer and tumor.
Fructus aurantii: the Chinese herbs of qi regulating type, property, flavor and meridian tropism: bitter, pungent and slightly cold; it enters spleen, stomach and large intestine meridians. The efficacy is as follows: break qi and remove food retention, resolve phlegm and remove abdominal mass. The main treatment is as follows: can be used for treating abdominal pain, constipation, dysentery, abdominal distention, thoracic obstruction, uterine prolapse, gastroptosis, proctoptosis, and food stagnation.
Tuckahoe, poria cocos: the diuresis and edema-relieving traditional Chinese medicines have the characteristics of flavor and meridian tropism: sweet and light taste, mild in nature; it enters heart, spleen and kidney meridians. The efficacy is as follows: induce diuresis to infiltrate water, invigorate spleen and tranquilize mind. The main treatment is as follows: used for edema diarrhea, dysuria, phlegm and fluid retention, palpitation and insomnia, and has the following effects: regulating immunity, resisting aging, resisting pathogenic microorganism, resisting tumor, promoting urination, and tonifying heart.
Chinese date: qi-tonifying traditional Chinese medicines, property, flavor and channel tropism: sweet taste and warm nature; it enters spleen, stomach and heart meridians. The efficacy is as follows: tonify middle-jiao and Qi, nourish blood and soothe nerves, and moderate drug property. The main treatment is as follows: can be used for treating weakness of spleen and stomach, anorexia, loose stool, blood deficiency, sallow complexion, and female viscera dryness.
Medicated leaven: digestion-promoting traditional Chinese medicines with the property and taste: sweet, pungent and warm; it enters spleen and stomach meridians. The efficacy is as follows: promote digestion, regulate stomach, stop diarrhea and relieve exterior syndrome. The main treatment is as follows: gastrointestinal symptoms caused by cold due to abdominal distention and fullness due to indigestion. The function is as follows: can promote secretion of digestive juice.
Wind prevention: the Chinese herbs with pungent and warm properties for relieving exterior syndrome, property and flavor enter meridians: pungent, sweet and slightly warm; it enters bladder, liver and spleen meridians. The efficacy is as follows: dispel wind and relieve exterior syndrome, alleviate pain and relieve spasm. The main treatment is as follows: can be used for treating exterior syndrome due to exogenous pathogenic factor, rheumatalgia, and common cold. The function is as follows: increasing resistance and immunity, resisting bacteria, relieving inflammation, relieving pain, relieving fever, and improving sleep.
Rhubarb: purgative herbs, property, flavor and channel tropism: bitter and cold; it enters stomach, large intestine, liver and pericardium meridians. The functions are as follows: purging pathogenic accumulation, clearing heat and purging fire, cooling blood and removing toxicity, activating blood and dispelling stasis. The main treatment is as follows: intestinal stagnation, constipation, hematemesis, epistaxis, conjunctival congestion, pharyngalgia, jaundice due to damp-heat, stranguria, gingival swelling and pain, pyocutaneous disease due to heat-toxin, scald due to water and fire, blood stasis, amenorrhea, and traumatic injury. The function is as follows: regulating immunity, reducing blood lipid, lowering blood pressure, resisting pathogenic microorganism, improving cardiovascular function, promoting urination, stopping bleeding, purging, protecting liver, and preventing and treating gastropathy and duodenal ulcer. Rhubarb, radix et rhizoma Rhei, due to its strong action of descending with sex, can wash intestines and stomach, push old and refresh, and has the effect of cutting off and taking the gate, so it is called: "general". Has the functions of clearing heat, constipation due to heat accumulation, coma and delirium (speaking, a murmur), clearing hollow viscera and heat, and eliminating heat accumulation. Heat accumulation in the intestines and stomach, yin fluid burn, constipation, and increased water circulation. Dysentery due to heat, damp-heat, accumulation in the intestinal tract, diarrhea with difficulty, bloody pus in stool, heat-purging and stagnation-removing, heat accumulation and yangming, heat descending, postpartum blood stasis, blood stasis and amenorrhea, diuresis and stranguria relieving.
Cassia twig: the pungent-warm exterior-releasing herbs have the following property-flavor effects: pungent, sweet and warm; it enters heart, lung and bladder meridians. The efficacy is as follows: induce sweating to release exterior, warm meridians and activate yang. The main treatment is as follows: can be used for treating wind-cold exterior syndrome, arthralgia due to wind-cold-dampness, arthralgia, edema, phlegm retention, thoracic obstruction, palpitation, amenorrhea due to stagnation, dysmenorrhea, and abdominal pain. The function is as follows: has antiinflammatory, antipyretic, analgesic, anticonvulsive, antiallergic, and pathogenic microorganism resisting effects.
Balloon flower: the herbs which can resolve phlegm enter meridians: bitter, pungent and mild; it enters lung meridian. The efficacy is as follows: expelling pus, dispersing lung qi, relieving sore throat, and eliminating phlegm. The main treatment is as follows: can be used for treating lung abscess, emesis, cough, excessive phlegm, pharyngalgia, and aphonia. The function is as follows: relieving cough, resisting ulcer, resisting inflammation, relieving fever, relieving pain, eliminating phlegm, reducing blood lipid, and lowering blood sugar.
Ligusticum wallichii: chinese herbs entering blood circulation and removing blood stasis, property and flavor entering meridian: warming and pungent; it enters liver, gallbladder and heart meridians. The efficacy is as follows: promoting blood circulation, activating qi-flowing, dispelling pathogenic wind and relieving pain. The main treatment is as follows: can be used for treating general pain, pain of chest, thoracic obstruction, pyocutaneous disease, swelling and pain, headache, rheumatalgia, and menoxenia. The function is as follows: regulating immunity, relieving asthma, resisting tumor, inhibiting platelet aggregation, improving renal and pulmonary functions, and improving cardiovascular function.
Herba schizonepetae: pungent-warm exterior-releasing herbs, property-flavor entering meridian: pungent and mild-warm; it enters lung and liver meridians. The efficacy is as follows: dispel wind, relieve exterior syndrome, promote eruption and stop bleeding. The main treatment is as follows: can be used for treating exterior syndrome due to exogenous pathogenic factors, rubella pruritus, measles without adequate eruption, pyocutaneous disease, swelling and pain, and hemorrhage. The function is as follows: has antiinflammatory, antipyretic, analgesic, hemostatic, and smooth muscle exciting effects.
White atractylodes rhizome: qi-tonifying traditional Chinese medicines, property, flavor and channel tropism: bitter, sweet and warm; it enters spleen and stomach meridians. The efficacy is as follows: tonify qi, invigorate spleen, dry dampness, induce diuresis, arrest sweating and prevent abortion. The main treatment is as follows: can be used for treating spleen qi deficiency, anorexia, loose stool, phlegm retention, edema, exterior deficiency, spontaneous perspiration, and threatened abortion. The function is as follows: regulating immunity, resisting tumor, protecting liver, lowering blood sugar, lowering blood pressure, resisting pathogenic microorganism, and promoting urination.
Honey-fried licorice root: the Chinese herbs entering qi tonics have the following properties: sweet and mild; it enters heart, spleen, lung and stomach meridians. The efficacy is as follows: invigorating spleen and replenishing qi, moistening lung for arresting cough, clearing away heat and toxic material, relieving spasm and pain, and alleviating drug property.
The main treatment is as follows: can be used for treating weakness of spleen and stomach, short breath, debilitation, cardiopalmus, cough, little phlegm, toxic heat, pyocutaneous disease, drug and food poisoning, toxic substance removing, abdominal pain, and limb spasm pain.
The novel coronavirus invades the respiratory system of a human body for 96 hours (four days) and enters lung epithelial cells to destroy protein layer and propagate, so the Chinese medicinal decoction is taken within 96 hours, and the virus can be effectively discharged out of the body in time through the sweating method (sweating) and the lower method (defecation) of the traditional Chinese medicine, thereby effectively playing the roles of epidemic prevention and control.
Epidemic diseases, viral diseases and infectious diseases have the symptoms, the incubation period is short (1-3 days), and the treatment method is the same as the above. Namely the Chinese medicine says that the different diseases are treated at the same time.
Example 1
A traditional Chinese medicine preparation for treating new coronavirus and viral diseases comprises the following traditional Chinese medicine raw materials by weight: 10g of mix-fried ephedra herb, 30g of almond, 30g of honeysuckle, 35g of gypsum, 20g of ginger, 30g of rhizoma atractylodis, 30g of spreading hedyotis herb, 25g of fructus aurantii, 40g of tuckahoe, 80g of Chinese date, 20g of medicated leaven, 35g of radix sileris, 40g of rhubarb, 30g of cassia twig, 30g of platycodon grandiflorum, 35g of ligusticum chuanxiong hort, 20g of schizonepeta, 40g of bighead atractylodes rhizome and 30g of honey-fried licorice root. Processing the above Chinese medicinal materials by conventional method, mixing, drying, pulverizing to 0.4cm, sieving to obtain fine powder, adding appropriate amount of water, and shaking to obtain watered pill.
Example 2
This example differs from example 1 in that:
raw materials: 120g of mix-fried ephedra herb, 120g of almond, 100g of honeysuckle, 10g of gypsum, 10g of ginger, 180g of rhizoma atractylodis, 60g of spreading hedyotis herb, 150g of fructus aurantii, 30g of tuckahoe, 100g of Chinese date, 150g of medicated leaven, 180g of radix sileris, 50g of rhubarb, 30g of cassia twig, 30g of platycodon grandiflorum, 20g of ligusticum chuanxiong hort, 100g of schizonepeta, 180g of bighead atractylodes rhizome and 200g of honey-fried licorice root.
Example 3
This example differs from example 1 in that:
raw materials: 10g of mix-fried ephedra herb, 50g of almond, 30g of honeysuckle, 95g of gypsum, 20g of ginger, 30g of rhizoma atractylodis, 120g of oldenlandia diffusa, 100g of fructus aurantii, 40g of poria cocos, 180g of Chinese date, 200g of medicated leaven, 35g of radix sileris, 20g of rheum officinale, 30g of cassia twig, 30g of platycodon grandiflorum, 85g of ligusticum chuanxiong hort, 80g of schizonepeta, 10g of bighead atractylodes rhizome and 60g of honey-fried.
Example 4
This example differs from example 1 in that:
raw materials: 3g of mix-fried ephedra herb, 30g of almond, 120g of honeysuckle, 120g of gypsum, 120g of ginger, 150g of rhizoma atractylodis, 130g of spreading hedyotis herb, 25g of fructus aurantii, 140g of tuckahoe, 90g of Chinese date, 30g of medicated leaven, 135g of radix sileris, 15g of rhubarb, 120g of cassia twig, 30g of platycodon grandiflorum, 135g of ligusticum chuanxiong hort, 30g of schizonepeta, 30g of bighead atractylodes rhizome and 20g of honey-fried licorice root.
And (3) clinical trials:
the beneficial effects of the traditional Chinese medicine preparation are further illustrated by clinical curative effect observation experiments.
Firstly, the applicable population of the formula of the invention is as follows:
(1) has asthma, dyspnea, cough, high fever, asthenia and ache all over, and the hospital diagnosis result is the early or middle stage patient of the novel coronavirus;
(2) no asthma, cough, high fever, hypodynamia and ache all over, and the diagnosis result in hospital is the suspected patient of the novel coronavirus;
(3) dyspnea, physical weakness and listlessness, and the hospital diagnosis result shows that the patient is a severe patient with the novel coronavirus, and the prescription of the invention is not easy to take;
(4) fever due to viral cold, bacterial cold, acute upper respiratory infection, influenza, gastrointestinal type common cold, fever due to exogenous pathogenic fever, food stagnation, or fever due to common cold.
Secondly, the taking method and the notice:
the taking method comprises the following steps: water pills: it is administered orally, twice daily, 20g each time.
Decoction: the medicine is decocted in water for oral administration twice a day, one bag is respectively taken in the morning and evening, and the volume is 210 ml/bag, and the medicine is taken warmly. The medicine can be taken by more than 8 months for women and infants in lactation period, the women in lactation period can be cured, and the infants can be cured by breast feeding.
Note that: it is contraindicated for the elderly, asthenia, hyperhidrosis, aversion to wind, sleepiness, diarrhea due to spleen deficiency, hypertension, heart disease, pregnant women, liver disease, and nephropathy. Forbidding during medicine taking: tobacco, wine, pungent, seafood, greasy, tonic, etc.
Third, the therapeutic effect
By 26 days 2 months, the formulation prepared in example 1 was used in 211 new coronary virus infection cases of pneumonia confirmed in 11 cities, four provinces, and by comprehensively observing changes in symptoms such as asthenia, fever, cough, pharyngalgia, and imaging, the data show that: 211 patients are effective after taking the medicine, and the effective cure rate is 98.01 percent. Wherein, after the 51 patients take the medicine, the symptoms are stable and not aggravated, and account for about 23.31 percent of the total observed cases; symptoms of 102 patients are obviously improved, accounting for about 48.57% of total observed cases; symptoms of 48 patients disappeared, accounting for about 22.75% of the total observed cases; 10 patients were released from quarantine or discharge and accounted for approximately 4.73% of total observed cases.
The preparation prepared in example 1 is also taken by 104 patients clinically diagnosed with bacterial cold and influenza, and the effective cure rate is 98.12% after taking for three days.
Typical cases are:
1. the patient is cured by Wangzhi, a woman is 19 years old, has cough and asthma, fever of 39 degrees, fatigue and ache all over, cold and nasal discharge, the diagnosis result in a hospital is novel coronavirus pneumonia, after the western medicines are taken ineffectively, the patient is cured by taking the traditional Chinese medicine prescription for three days, the body temperature of the patient is recovered to be normal of 36.5 degrees, the asthma is disappeared, the cough is relieved, the fatigue and ache all over are absent all over, and the patient is cured to be in a healthy state all over five days. The medicine can be cured for several months without repeated treatment.
2. The patients are male and 38 years old, fever is 39.2 degrees, cough and general pain are caused, the diagnosis result of the hospital is that the patients are suspected to have the novel coronavirus, the patients are improved one day by taking the traditional Chinese medicine formula, the body temperature is 37.2 degrees, the cough is reduced, the general pain is reduced, the body temperature is normal to 36.5 degrees after the patients take the traditional Chinese medicine formula for the second day, the patients have better cough, and the patients are recovered to be in a healthy state after the patients take the traditional Chinese medicine formula for the third day. The medicine can be cured for several months without repeated treatment.
3. The patient with the novel coronavirus pneumonia is diagnosed as a result of a hospital diagnosis, after the western medicine is invalid, the patient is improved after taking the traditional Chinese medicine prescription for one day, the body temperature is 37.3 degrees, the patient has no asthma and cough, the body ache of the patient is relieved, the patient is cured and recovered in a healthy state after taking the traditional Chinese medicine prescription for 36.9 degrees and slight cough after taking the traditional Chinese medicine for the second day and 36.5 degrees after taking the traditional Chinese medicine for the third day. The medicine can be cured for several months without repeated treatment.
4. In the case of Tang Dynasty, women are 62 years old, fever is 38.6 degrees, cough and asthma, general fatigue and pain, cold, watery nasal discharge and diarrhea are caused, the hospital diagnosis result shows that the patients with the novel coronavirus pneumonia have the symptoms of novel coronavirus pneumonia, after western medicines are not taken, the traditional Chinese medicine formula is taken for three days, the body temperature is 37.2, the asthma disappears, the cough is relieved, the cold and watery nasal discharge are not caused, the general fatigue and pain are not caused, and the health state is recovered after five days. The medicine can be cured for several months without repeated treatment.
5. Li Yi, male and 42 years old, fever 39.2 degrees, symptoms of high fever, hypodynamia, headache, general muscle and joint ache, respiratory symptoms of light, running nose, cough and sneeze, hospital diagnosis result is influenza (contagious), body temperature of 36.5 days after taking the traditional Chinese medicine preparation, recovery and health state. The medicine can be cured for several months without repeated treatment.
6. In the traditional Chinese medicine formula, the body temperature of a woman is 36.5 in three days, and the woman is recovered to be in a healthy state after taking the traditional Chinese medicine formula for three days. The medicine can be cured for several months without repeated treatment.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.

Claims (9)

1. The traditional Chinese medicine preparation for treating the new coronavirus and the viral diseases is characterized by comprising the following traditional Chinese medicine raw materials by weight: 3-230 g of mix-fried ephedra herb, 5-250 g of almond, 10-360 g of honeysuckle flower, 10-360 g of gypsum, 3-230 g of ginger, 10-360 g of rhizoma atractylodis, 10-360 g of oldenlandia diffusa, 5-250 g of fructus aurantii, 10-360 g of poria cocos, 10-500 g of Chinese date, 10-500 g of medicated leaven, 10-360 g of divaricate saposhnikovia root, 5-250 g of rheum officinale, 10-360 g of cassia twig, 12-380 g of platycodon grandiflorum, 5-250 g of ligusticum chuanxiong hort, 3-230 g of schizonepeta, 10-230 g of bighead atractylodes rhizome and 6-280 g of honey-fried licorice root.
2. The traditional Chinese medicine preparation for treating the new coronavirus and the viral disease as claimed in claim 1, which is characterized by comprising the following traditional Chinese medicine raw materials in parts by weight: 10-120 g of mix-fried ephedra, 20-150 g of almond, 30-100 g of honeysuckle, 30-120 g of gypsum, 10-120 g of ginger, 30-180 g of rhizoma atractylodis, 30-160 g of oldenlandia diffusa, 20-150 g of fructus aurantii, 30-150 g of poria cocos, 30-300 g of Chinese date, 20-200 g of medicated leaven, 20-180 g of radix sileris, 20-120 g of rheum officinale, 20-200 g of cassia twig, 30-330 g of platycodon grandiflorum, 20-200 g of ligusticum chuanxiong hort, 10-100 g of schizonepeta, 30-200 g of rhizoma atractylodis macrocephalae and 20-230 g of honey-fried licorice root.
3. The traditional Chinese medicine preparation for treating the new coronavirus and the viral disease as claimed in claim 1 or 2, which is characterized by comprising the following traditional Chinese medicine raw materials by weight: 10g of mix-fried ephedra herb, 30g of almond, 30g of honeysuckle, 35g of gypsum, 20g of ginger, 30g of rhizoma atractylodis, 30g of spreading hedyotis herb, 25g of fructus aurantii, 40g of tuckahoe, 80g of Chinese date, 20g of medicated leaven, 35g of radix sileris, 40g of rhubarb, 30g of cassia twig, 30g of platycodon grandiflorum, 35g of ligusticum chuanxiong hort, 20g of schizonepeta, 40g of bighead atractylodes rhizome and 30g of honey-fried licorice root.
4. The Chinese materia medica preparation for treating the new coronavirus and the viral disease as claimed in any one of claims 1 to 3, wherein the product form of the Chinese materia medica preparation is one of the following dosage forms: decoction, granule, and watered pill.
5. The traditional Chinese medicine preparation for treating the new coronavirus and the viral disease as claimed in claim 4, wherein when the traditional Chinese medicine preparation is a decoction, the preparation method comprises the following steps: weighing the traditional Chinese medicines according to the weight parts, adding clear water which is 10-15 times of the total weight of the raw materials, firstly soaking for 30-50 min, then boiling with strong fire, slightly boiling for 10-30 min, and then filtering to obtain a liquid; putting the medicinal residues into clear water with the weight 8-15 times of the total weight of the raw material medicines, boiling with strong fire, decocting with slow fire for 15-25 min, and filtering to obtain a filtrate; then putting the dregs into clear water with the weight 6-10 times of the total weight of the raw materials, boiling with strong fire, decocting with slow fire for 10-25 min, and filtering to obtain a filtrate; mixing the three decoctions, and packaging the mixed decoctions into 200ml bags.
6. The Chinese medicinal preparation for treating the new coronavirus and the viral disease as claimed in claim 4, wherein when the Chinese medicinal preparation is a watered pill, the preparation method comprises the following steps: weighing the traditional Chinese medicines according to the formula, processing according to a conventional method, mixing, drying, crushing to 0.4-0.6 cm, sieving to obtain fine powder, adding a proper amount of water, and shaking to prepare the watered pill.
7. The use of a Chinese medicinal preparation as claimed in any one of claims 1 to 4 in the manufacture of a medicament for the treatment of a new coronavirus.
8. The use of the Chinese medicinal preparation of any one of claims 1 to 4 in the preparation of medicaments for treating viral diseases, infectious diseases and epidemic diseases.
9. The use of claim 8, wherein the viral disease is a viral cold or a respiratory viral infection and the infectious disease is a bacterial cold.
CN202010461885.0A 2020-05-27 2020-05-27 Chinese medicinal preparation for treating new coronavirus and viral diseases, and its preparation method Pending CN111588828A (en)

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Application publication date: 20200828